Result of FASTA (ccds) for
pF1KE0778
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0778, 514 aa
1>>>pF1KE0778 514 - 514 aa - 514 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.3939+/-0.00151; mu= -2.2428+/- 0.086
mean_var=304.5797+/-72.709, 0's: 0 Z-trim(106.5): 643 B-trim: 212 in 1/50
Lambda= 0.073489
statistics sampled from 8260 (9035) to 8260 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.641), E-opt: 0.2 (0.278), width: 16
Scan time: 2.850
The best scores are: opt bits E(32554)
CCDS7789.1 STK33 gene_id:65975|Hs108|chr11 ( 514) 3341 368.9 7.5e-102
CCDS73254.1 STK33 gene_id:65975|Hs108|chr11 ( 473) 3062 339.3 5.7e-93
CCDS73253.1 STK33 gene_id:65975|Hs108|chr11 ( 327) 2144 241.8 8.7e-64
CCDS7092.1 CAMK1D gene_id:57118|Hs108|chr10 ( 357) 607 78.9 1.1e-14
CCDS7091.1 CAMK1D gene_id:57118|Hs108|chr10 ( 385) 607 78.9 1.1e-14
CCDS10851.1 PSKH1 gene_id:5681|Hs108|chr16 ( 424) 602 78.5 1.7e-14
CCDS81839.1 RPS6KA5 gene_id:9252|Hs108|chr14 ( 723) 598 78.3 3.3e-14
CCDS9893.1 RPS6KA5 gene_id:9252|Hs108|chr14 ( 802) 598 78.3 3.6e-14
CCDS2582.1 CAMK1 gene_id:8536|Hs108|chr3 ( 370) 585 76.6 5.4e-14
CCDS4103.1 CAMK4 gene_id:814|Hs108|chr5 ( 473) 567 74.8 2.4e-13
CCDS7336.1 CAMK2G gene_id:818|Hs108|chr10 ( 495) 561 74.2 3.9e-13
CCDS7337.1 CAMK2G gene_id:818|Hs108|chr10 ( 527) 561 74.2 4.1e-13
CCDS6240.1 PSKH2 gene_id:85481|Hs108|chr8 ( 385) 558 73.7 4.1e-13
CCDS73153.1 CAMK2G gene_id:818|Hs108|chr10 ( 539) 561 74.2 4.1e-13
CCDS31001.1 MAPKAPK2 gene_id:9261|Hs108|chr1 ( 400) 558 73.8 4.2e-13
CCDS7338.1 CAMK2G gene_id:818|Hs108|chr10 ( 556) 561 74.2 4.2e-13
CCDS12116.1 DAPK3 gene_id:1613|Hs108|chr19 ( 454) 553 73.3 6.6e-13
CCDS1466.1 MAPKAPK2 gene_id:9261|Hs108|chr1 ( 370) 549 72.8 7.7e-13
CCDS5489.1 CAMK2B gene_id:816|Hs108|chr7 ( 449) 543 72.2 1.4e-12
CCDS5488.1 CAMK2B gene_id:816|Hs108|chr7 ( 479) 543 72.3 1.4e-12
CCDS5487.1 CAMK2B gene_id:816|Hs108|chr7 ( 492) 543 72.3 1.5e-12
CCDS5486.1 CAMK2B gene_id:816|Hs108|chr7 ( 503) 543 72.3 1.5e-12
CCDS43573.1 CAMK2B gene_id:816|Hs108|chr7 ( 517) 543 72.3 1.5e-12
CCDS5485.1 CAMK2B gene_id:816|Hs108|chr7 ( 518) 543 72.3 1.5e-12
CCDS81286.1 RPS6KA1 gene_id:6195|Hs108|chr1 ( 719) 546 72.8 1.5e-12
CCDS284.1 RPS6KA1 gene_id:6195|Hs108|chr1 ( 735) 546 72.8 1.5e-12
CCDS30649.1 RPS6KA1 gene_id:6195|Hs108|chr1 ( 744) 546 72.8 1.5e-12
CCDS5484.1 CAMK2B gene_id:816|Hs108|chr7 ( 542) 543 72.3 1.6e-12
CCDS3704.1 CAMK2D gene_id:817|Hs108|chr4 ( 478) 540 71.9 1.8e-12
CCDS43263.1 CAMK2D gene_id:817|Hs108|chr4 ( 478) 540 71.9 1.8e-12
CCDS5483.1 CAMK2B gene_id:816|Hs108|chr7 ( 666) 543 72.4 1.8e-12
CCDS54797.1 CAMK2D gene_id:817|Hs108|chr4 ( 489) 540 71.9 1.8e-12
CCDS47127.1 CAMK2D gene_id:817|Hs108|chr4 ( 492) 540 71.9 1.8e-12
CCDS82950.1 CAMK2D gene_id:817|Hs108|chr4 ( 498) 540 72.0 1.8e-12
CCDS3703.1 CAMK2D gene_id:817|Hs108|chr4 ( 499) 540 72.0 1.8e-12
CCDS82948.1 CAMK2D gene_id:817|Hs108|chr4 ( 512) 540 72.0 1.9e-12
CCDS5525.1 PHKG1 gene_id:5260|Hs108|chr7 ( 387) 537 71.5 1.9e-12
CCDS82949.1 CAMK2D gene_id:817|Hs108|chr4 ( 533) 540 72.0 1.9e-12
CCDS10188.1 DAPK2 gene_id:23604|Hs108|chr15 ( 370) 536 71.4 2e-12
CCDS83147.1 RPS6KA2 gene_id:6196|Hs108|chr6 ( 644) 541 72.2 2e-12
CCDS5294.1 RPS6KA2 gene_id:6196|Hs108|chr6 ( 733) 541 72.2 2.2e-12
CCDS34570.1 RPS6KA2 gene_id:6196|Hs108|chr6 ( 741) 541 72.2 2.2e-12
CCDS83148.1 RPS6KA2 gene_id:6196|Hs108|chr6 ( 758) 541 72.2 2.3e-12
CCDS43386.1 CAMK2A gene_id:815|Hs108|chr5 ( 478) 536 71.5 2.4e-12
CCDS43387.1 CAMK2A gene_id:815|Hs108|chr5 ( 489) 536 71.5 2.4e-12
CCDS11213.1 ULK2 gene_id:9706|Hs108|chr17 (1036) 543 72.6 2.4e-12
CCDS43842.1 DAPK1 gene_id:1612|Hs108|chr9 (1430) 537 72.1 4.7e-12
CCDS14197.1 RPS6KA3 gene_id:6197|Hs108|chrX ( 740) 529 71.0 5.4e-12
CCDS13843.1 CHEK2 gene_id:11200|Hs108|chr22 ( 543) 518 69.7 9.8e-12
CCDS33629.1 CHEK2 gene_id:11200|Hs108|chr22 ( 586) 518 69.7 1e-11
>>CCDS7789.1 STK33 gene_id:65975|Hs108|chr11 (514 aa)
initn: 3341 init1: 3341 opt: 3341 Z-score: 1942.1 bits: 368.9 E(32554): 7.5e-102
Smith-Waterman score: 3341; 100.0% identity (100.0% similar) in 514 aa overlap (1-514:1-514)
10 20 30 40 50 60
pF1KE0 MADSGLDKKSTKCPDCSSASQKDVLCVCSSKTRVPPVLVVEMSQTSSIGSAESLISLERK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 MADSGLDKKSTKCPDCSSASQKDVLCVCSSKTRVPPVLVVEMSQTSSIGSAESLISLERK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KEKNINRDITSRKDLPSRTSNVERKASQQQWGRGNFTEGKVPHIRIENGAAIEEIYTFGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 KEKNINRDITSRKDLPSRTSNVERKASQQQWGRGNFTEGKVPHIRIENGAAIEEIYTFGR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 ILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 VFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 VFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 LENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 SQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 SQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 LMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 LMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 TEEKLKSYQPWGNVPDANYTSDEEEEKQSTAYEKQFPATSKDNFDMCSSSFTSSKLLPAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 TEEKLKSYQPWGNVPDANYTSDEEEEKQSTAYEKQFPATSKDNFDMCSSSFTSSKLLPAE
430 440 450 460 470 480
490 500 510
pF1KE0 IKGEMEKTPVTPSQGTATKYPAKSGALSRTKKKL
::::::::::::::::::::::::::::::::::
CCDS77 IKGEMEKTPVTPSQGTATKYPAKSGALSRTKKKL
490 500 510
>>CCDS73254.1 STK33 gene_id:65975|Hs108|chr11 (473 aa)
initn: 3062 init1: 3062 opt: 3062 Z-score: 1782.6 bits: 339.3 E(32554): 5.7e-93
Smith-Waterman score: 3062; 100.0% identity (100.0% similar) in 473 aa overlap (42-514:1-473)
20 30 40 50 60 70
pF1KE0 KCPDCSSASQKDVLCVCSSKTRVPPVLVVEMSQTSSIGSAESLISLERKKEKNINRDITS
::::::::::::::::::::::::::::::
CCDS73 MSQTSSIGSAESLISLERKKEKNINRDITS
10 20 30
80 90 100 110 120 130
pF1KE0 RKDLPSRTSNVERKASQQQWGRGNFTEGKVPHIRIENGAAIEEIYTFGRILGKGSFGIVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 RKDLPSRTSNVERKASQQQWGRGNFTEGKVPHIRIENGAAIEEIYTFGRILGKGSFGIVI
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE0 EATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQVFETPKKMYLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 EATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQVFETPKKMYLV
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE0 MELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 MELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLI
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE0 DDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 DDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGV
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE0 VMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 VMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRIT
280 290 300 310 320 330
380 390 400 410 420 430
pF1KE0 AKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPSTEEKLKSYQPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 AKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPSTEEKLKSYQPW
340 350 360 370 380 390
440 450 460 470 480 490
pF1KE0 GNVPDANYTSDEEEEKQSTAYEKQFPATSKDNFDMCSSSFTSSKLLPAEIKGEMEKTPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 GNVPDANYTSDEEEEKQSTAYEKQFPATSKDNFDMCSSSFTSSKLLPAEIKGEMEKTPVT
400 410 420 430 440 450
500 510
pF1KE0 PSQGTATKYPAKSGALSRTKKKL
:::::::::::::::::::::::
CCDS73 PSQGTATKYPAKSGALSRTKKKL
460 470
>>CCDS73253.1 STK33 gene_id:65975|Hs108|chr11 (327 aa)
initn: 2144 init1: 2144 opt: 2144 Z-score: 1258.6 bits: 241.8 E(32554): 8.7e-64
Smith-Waterman score: 2144; 100.0% identity (100.0% similar) in 327 aa overlap (188-514:1-327)
160 170 180 190 200 210
pF1KE0 KLLEREVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRW
::::::::::::::::::::::::::::::
CCDS73 MYLVMELCEDGELKEILDRKGHFSENETRW
10 20 30
220 230 240 250 260 270
pF1KE0 IIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 IIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSE
40 50 60 70 80 90
280 290 300 310 320 330
pF1KE0 AMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 AMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRK
100 110 120 130 140 150
340 350 360 370 380 390
pF1KE0 GELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 GELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEM
160 170 180 190 200 210
400 410 420 430 440 450
pF1KE0 MKEWKNNPESVEENTTEEKNKPSTEEKLKSYQPWGNVPDANYTSDEEEEKQSTAYEKQFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 MKEWKNNPESVEENTTEEKNKPSTEEKLKSYQPWGNVPDANYTSDEEEEKQSTAYEKQFP
220 230 240 250 260 270
460 470 480 490 500 510
pF1KE0 ATSKDNFDMCSSSFTSSKLLPAEIKGEMEKTPVTPSQGTATKYPAKSGALSRTKKKL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 ATSKDNFDMCSSSFTSSKLLPAEIKGEMEKTPVTPSQGTATKYPAKSGALSRTKKKL
280 290 300 310 320
>>CCDS7092.1 CAMK1D gene_id:57118|Hs108|chr10 (357 aa)
initn: 581 init1: 310 opt: 607 Z-score: 377.4 bits: 78.9 E(32554): 1.1e-14
Smith-Waterman score: 674; 39.6% identity (71.4% similar) in 273 aa overlap (112-384:19-282)
90 100 110 120 130 140
pF1KE0 VERKASQQQWGRGNFTEGKVPHIRIENGAAIEEIYTFGRILGKGSFGIVIEATDKETETK
:..:. : . :: :.:. :. : .: :
CCDS70 MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKL
10 20 30 40
150 160 170 180 190 200
pF1KE0 WAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELK
.:.: . : :: .. . .: :. .:...:::.:. ::...:.:...::::.: :::
CCDS70 FAVKCIPK-KALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELF
50 60 70 80 90 100
210 220 230 240 250 260
pF1KE0 EILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNI
. . .:: ..:... .:... .:. ::: ::::::: ::.. :. :....:
CCDS70 DRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQ--DEESKIM---
110 120 130 140 150 160
270 280 290 300 310 320
pF1KE0 KVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEP
..::::. : ......: : :::: :.::::.. . ::. : :::::. :.:: : :
CCDS70 -ISDFGLS-KMEGKGDVMSTA-CGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYP
170 180 190 200 210
330 340 350 360 370 380
pF1KE0 PFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWL
:: .. :::: : :.: .:.. :..::: ::. ...::. :: .: : .. . :.
CCDS70 PFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI
220 230 240 250 260 270
390 400 410 420 430 440
pF1KE0 TGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPSTEEKLKSYQPWGNVPDANYTS
.:.
CCDS70 AGDTALNKNIHESVSAQIRKNFAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSL
280 290 300 310 320 330
>>CCDS7091.1 CAMK1D gene_id:57118|Hs108|chr10 (385 aa)
initn: 581 init1: 310 opt: 607 Z-score: 377.0 bits: 78.9 E(32554): 1.1e-14
Smith-Waterman score: 674; 39.6% identity (71.4% similar) in 273 aa overlap (112-384:19-282)
90 100 110 120 130 140
pF1KE0 VERKASQQQWGRGNFTEGKVPHIRIENGAAIEEIYTFGRILGKGSFGIVIEATDKETETK
:..:. : . :: :.:. :. : .: :
CCDS70 MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKL
10 20 30 40
150 160 170 180 190 200
pF1KE0 WAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELK
.:.: . : :: .. . .: :. .:...:::.:. ::...:.:...::::.: :::
CCDS70 FAVKCIPK-KALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELF
50 60 70 80 90 100
210 220 230 240 250 260
pF1KE0 EILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNI
. . .:: ..:... .:... .:. ::: ::::::: ::.. :. :....:
CCDS70 DRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQ--DEESKIM---
110 120 130 140 150 160
270 280 290 300 310 320
pF1KE0 KVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEP
..::::. : ......: : :::: :.::::.. . ::. : :::::. :.:: : :
CCDS70 -ISDFGLS-KMEGKGDVMSTA-CGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYP
170 180 190 200 210
330 340 350 360 370 380
pF1KE0 PFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWL
:: .. :::: : :.: .:.. :..::: ::. ...::. :: .: : .. . :.
CCDS70 PFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI
220 230 240 250 260 270
390 400 410 420 430 440
pF1KE0 TGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPSTEEKLKSYQPWGNVPDANYTS
.:.
CCDS70 AGDTALNKNIHESVSAQIRKNFAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSL
280 290 300 310 320 330
>>CCDS10851.1 PSKH1 gene_id:5681|Hs108|chr16 (424 aa)
initn: 594 init1: 340 opt: 602 Z-score: 373.7 bits: 78.5 E(32554): 1.7e-14
Smith-Waterman score: 605; 33.8% identity (65.2% similar) in 290 aa overlap (100-388:82-362)
70 80 90 100 110 120
pF1KE0 TSRKDLPSRTSNVERKASQQQWGRGNFTEGKVPHIRIENGAAIEEIYTFGRILGKGSFGI
.: . : . . : . ..:.:::.
CCDS10 FPAASQYAHPCPGPPTAGHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSR
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 VIEATDKETETKWAIKKVN-KEKAGSSAVKLLEREVNILKSVKHEHIIHLEQVFETPKKM
:... . :. .::: .. : . : .. : :. .:. :.: .::.: .:::: ...
CCDS10 VVRVEHRATRQPYAIKMIETKYREGR---EVCESELRVLRRVRHANIIQLVEVFETQERV
120 130 140 150 160
190 200 210 220 230 240
pF1KE0 YLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKS
:.:::: ::: . . :: :.: .. ..: . ... ::: :.::::: ::..
CCDS10 YMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYH
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE0 SLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQCDIWS
:.. : .:::::: ... .. ....::::: :.::::. . :... :.:.
CCDS10 PGTDSK------IIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWA
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE0 IGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAH
.::. :.:: : :: ... .:.. : .:. . . : :.:. ::. . .:. :::.
CCDS10 LGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE0 RITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPSTEEKLKSY
:.:: . : . :... ::
CCDS10 RMTALQALRHPWVVSMAASSSMKNLHRSISQNLLKRASSRCQSTKSAQSTRSSRSTRSNK
350 360 370 380 390 400
>>CCDS81839.1 RPS6KA5 gene_id:9252|Hs108|chr14 (723 aa)
initn: 310 init1: 274 opt: 598 Z-score: 368.5 bits: 78.3 E(32554): 3.3e-14
Smith-Waterman score: 598; 32.1% identity (64.7% similar) in 368 aa overlap (122-480:353-699)
100 110 120 130 140 150
pF1KE0 GRGNFTEGKVPHIRIENGAAIEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEK
::.:::.: . . :... .:.: ..:.
CCDS81 RPGVTNVARSAMMKDSPFYQHYDLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKIISKRM
330 340 350 360 370 380
160 170 180 190 200 210
pF1KE0 AGSSAVKLLEREVNILKSVK-HEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHF
... ..:.. :: . : .:..:..::. . .::::: . ::: : . .: ::
CCDS81 EANT-----QKEITALKLCEGHPNIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHF
390 400 410 420 430
220 230 240 250 260 270
pF1KE0 SENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAV
::.:. .:...:.::....:. .:::::: ::.. . :.:. ::.::. :::.:
CCDS81 SETEASYIMRKLVSAVSHMHDVGVVHRDLKPENLL----FTDEND--NLEIKIIDFGFAR
440 450 460 470 480 490
280 290 300 310 320
pF1KE0 KKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLA-----
: .. :.. : : : :::... . :...::.::.::..: .: :. :: .
CCDS81 LKPPDNQP-LKTPCFTLHYAAPELLNQNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSL
500 510 520 530 540 550
330 340 350 360 370 380
pF1KE0 --SSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLT-
.: .... :.::.. ::. .:...:. ::.... :. ::: .:. . : :.::
CCDS81 TCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLLTVDPNKRLKMSGLRYNEWLQD
560 570 580 590 600 610
390 400 410 420 430 440
pF1KE0 GNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPSTEEKLKSYQPWGNVPDANYTSD
:..::: : . ... .. . : . :: . : : :: : ..
CCDS81 GSQLSS-NPLMTPDILGSSGAAVHTCVKATFHAFNKYKREGF--CLQ---NVDKAPLAKR
620 630 640 650 660
450 460 470 480 490 500
pF1KE0 EEEEKQSTAYEKQFPATSKDNFDMCSSSFTSSKLLPAEIKGEMEKTPVTPSQGTATKYPA
.. .: ::. : . .:... . ::: . .: :..
CCDS81 RKMKKTSTSTETR---SSSSESSHSSSSHSHGKTTPTKTLQPSNPADSNNPETLFQFSDS
670 680 690 700 710 720
510
pF1KE0 KSGALSRTKKKL
CCDS81 VA
>>CCDS9893.1 RPS6KA5 gene_id:9252|Hs108|chr14 (802 aa)
initn: 310 init1: 274 opt: 598 Z-score: 367.9 bits: 78.3 E(32554): 3.6e-14
Smith-Waterman score: 598; 32.1% identity (64.7% similar) in 368 aa overlap (122-480:432-778)
100 110 120 130 140 150
pF1KE0 GRGNFTEGKVPHIRIENGAAIEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEK
::.:::.: . . :... .:.: ..:.
CCDS98 RPGVTNVARSAMMKDSPFYQHYDLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKIISKRM
410 420 430 440 450 460
160 170 180 190 200 210
pF1KE0 AGSSAVKLLEREVNILKSVK-HEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHF
... ..:.. :: . : .:..:..::. . .::::: . ::: : . .: ::
CCDS98 EANT-----QKEITALKLCEGHPNIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHF
470 480 490 500 510
220 230 240 250 260 270
pF1KE0 SENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAV
::.:. .:...:.::....:. .:::::: ::.. . :.:. ::.::. :::.:
CCDS98 SETEASYIMRKLVSAVSHMHDVGVVHRDLKPENLL----FTDEND--NLEIKIIDFGFAR
520 530 540 550 560 570
280 290 300 310 320
pF1KE0 KKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLA-----
: .. :.. : : : :::... . :...::.::.::..: .: :. :: .
CCDS98 LKPPDNQP-LKTPCFTLHYAAPELLNQNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSL
580 590 600 610 620
330 340 350 360 370 380
pF1KE0 --SSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLT-
.: .... :.::.. ::. .:...:. ::.... :. ::: .:. . : :.::
CCDS98 TCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLLTVDPNKRLKMSGLRYNEWLQD
630 640 650 660 670 680
390 400 410 420 430 440
pF1KE0 GNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPSTEEKLKSYQPWGNVPDANYTSD
:..::: : . ... .. . : . :: . : : :: : ..
CCDS98 GSQLSS-NPLMTPDILGSSGAAVHTCVKATFHAFNKYKREGF--CLQ---NVDKAPLAKR
690 700 710 720 730 740
450 460 470 480 490 500
pF1KE0 EEEEKQSTAYEKQFPATSKDNFDMCSSSFTSSKLLPAEIKGEMEKTPVTPSQGTATKYPA
.. .: ::. : . .:... . ::: . .: :..
CCDS98 RKMKKTSTSTETR---SSSSESSHSSSSHSHGKTTPTKTLQPSNPADSNNPETLFQFSDS
750 760 770 780 790 800
510
pF1KE0 KSGALSRTKKKL
CCDS98 VA
>>CCDS2582.1 CAMK1 gene_id:8536|Hs108|chr3 (370 aa)
initn: 616 init1: 342 opt: 585 Z-score: 364.7 bits: 76.6 E(32554): 5.4e-14
Smith-Waterman score: 677; 39.0% identity (68.6% similar) in 290 aa overlap (99-384:3-279)
70 80 90 100 110 120
pF1KE0 ITSRKDLPSRTSNVERKASQQQWGRGNFTEGKVPHIRIENGAAIEEIYTFGRILGKGSFG
: : : ... :..:: : .:: :.:.
CCDS25 MLGAVEGPRWKQAEDIRDIYDFRDVLGTGAFS
10 20 30
130 140 150 160 170 180
pF1KE0 IVIEATDKETETKWAIKKVNKE----KAGSSAVKLLEREVNILKSVKHEHIIHLEQVFET
:: : ::.:. ::: . :: : :: .: :. .:...:: .:. :....:.
CCDS25 EVILAEDKRTQKLVAIKCIAKEALEGKEGS-----MENEIAVLHKIKHPNIVALDDIYES
40 50 60 70 80
190 200 210 220 230 240
pF1KE0 PKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENI
..::.:.: ::: . . .:: ..: .. .: .. .:. :::. ::::::: ::.
CCDS25 GGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENL
90 100 110 120 130 140
250 260 270 280 290 300
pF1KE0 MVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQC
. : .:....: ..::::. :. ..:...:::: :.::::.. . ::.
CCDS25 LYYS--LDEDSKIM----ISDFGLS--KMEDPGSVLSTACGTPGYVAPEVLAQKPYSKAV
150 160 170 180 190
310 320 330 340 350 360
pF1KE0 DIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKV
: :::::. :.:: : ::: .. :::: : :.: .:.. :..::: ::. ...::.
CCDS25 DCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEK
200 210 220 230 240 250
370 380 390 400 410 420
pF1KE0 DPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPSTEEK
:: .:.: .. :.. :..:.
CCDS25 DPEKRFTCEQALQHPWIAGDTALDKNIHQSVSEQIKKNFAKSKWKQAFNATAVVRHMRKL
260 270 280 290 300 310
>>CCDS4103.1 CAMK4 gene_id:814|Hs108|chr5 (473 aa)
initn: 365 init1: 215 opt: 567 Z-score: 353.0 bits: 74.8 E(32554): 2.4e-13
Smith-Waterman score: 567; 31.8% identity (65.6% similar) in 308 aa overlap (97-401:25-320)
70 80 90 100 110 120
pF1KE0 RDITSRKDLPSRTSNVERKASQQQWGRGNFTEGKVPHIRIE--NGAAIEEIYTFGRILGK
: . :: :. : :. ... ::.
CCDS41 MLKVTVPSCSASSCSSVTASAAPGTASLVPDYWIDGSNRDALSDFFEVESELGR
10 20 30 40 50
130 140 150 160 170 180
pF1KE0 GSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQVFET
:. .:: . .: :. .:.: ..: . :... :...: ..: .::.:...:::
CCDS41 GATSIVYRCKQKGTQKPYALKVLKK----TVDKKIVRTEIGVLLRLSHPNIIKLKEIFET
60 70 80 90 100 110
190 200 210 220 230 240
pF1KE0 PKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENI
: .. ::.:: ::: . . .::..:: .. .... :.::::.: ::::::: ::.
CCDS41 PTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENL
120 130 140 150 160 170
250 260 270 280 290 300
pF1KE0 MVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQC
. . : .:..::::. : . .......:::: : :::.. . :. .
CCDS41 LYATPAPDAP------LKIADFGLS--KIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEV
180 190 200 210 220
310 320 330 340 350 360
pF1KE0 DIWSIGVVMYMLLRGEPPFL-ASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMK
:.::.:.. :.:: : :: ... .:. : . : .: . :. .: ::.....:.
CCDS41 DMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIV
230 240 250 260 270 280
370 380 390 400 410 420
pF1KE0 VDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPSTEE
.:: .:.:. . :.. :.::. . :. .. . ..:.
CCDS41 LDPKKRLTTFQALQHPWVTGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSRLGSA
290 300 310 320 330 340
430 440 450 460 470 480
pF1KE0 KLKSYQPWGNVPDANYTSDEEEEKQSTAYEKQFPATSKDNFDMCSSSFTSSKLLPAEIKG
CCDS41 SSSHGSIQESHKASRDPSPIQDGNEDMKAIPEGEKIQGDGAQAAVKGAQAELMKVQALEK
350 360 370 380 390 400
514 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:26:09 2016 done: Sat Nov 5 18:26:10 2016
Total Scan time: 2.850 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]