FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0779, 348 aa 1>>>pF1KE0779 348 - 348 aa - 348 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.1456+/-0.000926; mu= 4.2887+/- 0.054 mean_var=284.7071+/-63.747, 0's: 0 Z-trim(114.1): 400 B-trim: 0 in 0/50 Lambda= 0.076011 statistics sampled from 14186 (14717) to 14186 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.79), E-opt: 0.2 (0.452), width: 16 Scan time: 3.230 The best scores are: opt bits E(32554) CCDS42631.1 SBK2 gene_id:646643|Hs108|chr19 ( 348) 2363 272.3 4.2e-73 CCDS74457.1 SBK3 gene_id:100130827|Hs108|chr19 ( 359) 771 97.7 1.5e-20 CCDS32416.1 SBK1 gene_id:388228|Hs108|chr16 ( 424) 734 93.8 2.9e-19 >>CCDS42631.1 SBK2 gene_id:646643|Hs108|chr19 (348 aa) initn: 2363 init1: 2363 opt: 2363 Z-score: 1425.8 bits: 272.3 E(32554): 4.2e-73 Smith-Waterman score: 2363; 99.4% identity (99.4% similar) in 348 aa overlap (1-348:1-348) 10 20 30 40 50 60 pF1KE0 MPGKQSEEGPAEAGASEDSEEEGLGGLTLEELQQGQEAARALEDMMTLSAQTLVRAEVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MPGKQSEEGPAEAGASEDSEEEGLGGLTLEELQQGQEAARALEDMMTLSAQTLVRAEVDE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 LYEEVRPLGQGRYGRVLLVTHRQKGTPLALKQLPKPRTSLRGFLYEFCVGLSLGAHSAIV ::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LYEEVRPLGQGCYGRVLLVTHRQKGTPLALKQLPKPRTSLRGFLYEFCVGLSLGAHSAIV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TAYGIGIESAHSYSFLTEPVLHGDLMAFIQPKVGLPQPAVHRCAAQLASALEYIHARGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 TAYGIGIESAHSYSFLTEPVLHGDLMAFIQPKVGLPQPAVHRCAAQLASALEYIHARGLV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 YRDLKPENVLVCDPACRRFKLTDFGHTRPRGTLLRLAGPPIPYTAPELCAPPPLPEGLPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 YRDLKPENVLVCDPACRRFKLTDFGHTRPRGTLLRLAGPPIPYTAPELCAPPPLPEGLPI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 QPALDAWALGVLLFCLLTGYFPWDRPLAEADPFYEDFLIWQASGQPRDRPQPWFGLAPAA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :: CCDS42 QPALDAWALGVLLFCLLTGYFPWDRPLAEADPFYEDFLIWQASGQPRDRPQPWFGLAAAA 250 260 270 280 290 300 310 320 330 340 pF1KE0 DALLRGLLDPHPRRRSAVIAIREHLGRPWRQREGEAEAVGAVEEEAGQ :::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 DALLRGLLDPHPRRRSAVIAIREHLGRPWRQREGEAEAVGAVEEEAGQ 310 320 330 340 >>CCDS74457.1 SBK3 gene_id:100130827|Hs108|chr19 (359 aa) initn: 746 init1: 284 opt: 771 Z-score: 482.2 bits: 97.7 E(32554): 1.5e-20 Smith-Waterman score: 771; 42.0% identity (65.7% similar) in 324 aa overlap (28-345:8-327) 10 20 30 40 50 pF1KE0 MPGKQSEEGPAEAGASEDSEEEGLGGLTLEELQQGQEAARALEDMMTLSAQ--TLVRAEV : :. . ...: ::. .. :... : ::. CCDS74 MERRASETPEDGDPEEDTATALQRLVELTTSRVTPVRSLR 10 20 30 40 60 70 80 90 100 110 pF1KE0 DELYEEVRPLGQGRYGRVLLVTHRQKGTPLALKQLPKPRTSLRGFLYEFCVGLSLGAHSA :. :. .: ::.: ::::::. .: : .::: : . . :: ::::: ..:: . CCDS74 DQ-YHLIRKLGSGSYGRVLLAQPHQGGPAVALKLLRRDLVLRSTFLREFCVGRCVSAHPG 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 IVTAYGIGIESAHSYSFLTEPVLHGDLMAFIQPKVGLPQPAVHRCAAQLASALEYIHARG .. . . ... . ..: : . ::: ...: . :::. :.: .::::.::...:.:: CCDS74 LLQTLAGPLQTPRYFAFAQEYAPCGDLSGMLQER-GLPELLVKRVVAQLAGALDFLHSRG 100 110 120 130 140 150 180 190 200 210 220 230 pF1KE0 LVYRDLKPENVLVCDPACRRFKLTDFGHTRPRGTLLRLAGPPIPYTAPELCAPPPLPEGL ::. :.::.:::: ::.: : : :.: :::.:. :.: . :::: : :. : CCDS74 LVHADVKPDNVLVFDPVCSRVALGDLGLTRPEGSPTPAPPVPLPTAPPELCLLLP-PDTL 160 170 180 190 200 210 240 250 260 270 280 290 pF1KE0 PIQPALDAWALGVLLFCLLTGYFPWDRPLAEADPFYEDFLIWQASG-QPRDRPQPWFGLA :..::.:.:.::::::: :. :::: :: .: .: : : .. :: . : :: .: CCDS74 PLRPAVDSWGLGVLLFCAATACFPWDVALAP-NPEFEAFAGWVTTKPQPPQPPPPWDQFA 220 230 240 250 260 270 300 310 320 330 340 pF1KE0 PAADALLRGLLDPHPRRRSAVIAIREHLGRPWR---QREGEAEAVGAVEEEAGQ : : :::.:::: :. :: .:. . :: : .::: . .:: : CCDS74 PPALALLQGLLDLDPETRSPPLAVLDFLGDDWGLQGNREGPGVLGSAVSYEDREEGGSSL 280 290 300 310 320 330 CCDS74 EEWTDEGDDSKSGGRTGTDGGAP 340 350 >>CCDS32416.1 SBK1 gene_id:388228|Hs108|chr16 (424 aa) initn: 713 init1: 539 opt: 734 Z-score: 459.5 bits: 93.8 E(32554): 2.9e-19 Smith-Waterman score: 734; 42.9% identity (69.6% similar) in 273 aa overlap (43-315:34-303) 20 30 40 50 60 70 pF1KE0 AGASEDSEEEGLGGLTLEELQQGQEAARALEDMMTLSAQTLVRAEVDELYEEVRPLGQGR :::..:. .::. ..: . :: :: ::.: CCDS32 GCPEPEPPRSLTCCGPGTAPGPGAGVPLLTEDMQALTLRTLAASDVTKHYELVRELGKGT 10 20 30 40 50 60 80 90 100 110 120 130 pF1KE0 YGRVLLVTHRQKGTPLALKQLPKPRTSLRGFLYEFCVGLSLGAHSAIVTAYGIGIESAHS ::.: ::... :: .::: . : .:.:..:: : . ::.. :. .. . .:. CCDS32 YGKVDLVVYKGTGTKMALKFVNKSKTKLKNFLREVSITNSLSSSPFIIKVFDVVFETEDC 70 80 90 100 110 120 140 150 160 170 180 190 pF1KE0 YSFLTEPVLHGDLMAFIQPKVGLPQPAVHRCAAQLASALEYIHARGLVYRDLKPENVLVC : : : . :::. .: :.::::. .:.::. ::. ::...:.: ::.::.::::::. CCDS32 YVFAQEYAPAGDLFDIIPPQVGLPEDTVKRCVQQLGLALDFMHGRQLVHRDIKPENVLLF 130 140 150 160 170 180 200 210 220 230 240 250 pF1KE0 DPACRRFKLTDFGHTRPRGTLLRLAGPPIPYTAPELCAPPPLPEGLPIQPALDAWALGVL : ::: ::.::: :: : .. .. :::::::.: .:: .. ..:.::.::: CCDS32 DRECRRVKLADFGMTRRVGCRVKRVSGTIPYTAPEVCQAGR-ADGLAVDTGVDVWAFGVL 190 200 210 220 230 240 260 270 280 290 300 310 pF1KE0 LFCLLTGYFPWDRPLAEADPFYEDFLIWQASGQPRDRPQPWFGLAPAADALLRGLLDPHP .::.::: :::. . :: :.:.:. :: . : :. : .. : ... :: .: CCDS32 IFCVLTGNFPWE-AASGADAFFEEFVRWQRGRLP-GLPSQWRRFTEPALRMFQRLLALEP 250 260 270 280 290 300 320 330 340 pF1KE0 RRRSAVIAIREHLGRPWRQREGEAEAVGAVEEEAGQ .:: CCDS32 ERRGPAKEVFRFLKHELTSELRRRPSHRARKPPGDRPPAAGPLRLEAPGPLKRTVLTESG 310 320 330 340 350 360 348 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 18:04:36 2016 done: Sat Nov 5 18:04:37 2016 Total Scan time: 3.230 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]