FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0781, 350 aa 1>>>pF1KE0781 350 - 350 aa - 350 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2055+/-0.000927; mu= 11.2274+/- 0.055 mean_var=80.3515+/-15.598, 0's: 0 Z-trim(105.6): 78 B-trim: 54 in 1/51 Lambda= 0.143079 statistics sampled from 8429 (8509) to 8429 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.638), E-opt: 0.2 (0.261), width: 16 Scan time: 2.650 The best scores are: opt bits E(32554) CCDS1887.1 PLEK gene_id:5341|Hs108|chr2 ( 350) 2367 498.4 3.6e-141 CCDS9782.1 PLEK2 gene_id:26499|Hs108|chr14 ( 353) 859 187.2 1.8e-47 >>CCDS1887.1 PLEK gene_id:5341|Hs108|chr2 (350 aa) initn: 2367 init1: 2367 opt: 2367 Z-score: 2648.0 bits: 498.4 E(32554): 3.6e-141 Smith-Waterman score: 2367; 100.0% identity (100.0% similar) in 350 aa overlap (1-350:1-350) 10 20 30 40 50 60 pF1KE0 MEPKRIREGYLVKKGSVFNTWKPMWVVLLEDGIEFYKKKSDNSPKGMIPLKGSTLTSPCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 MEPKRIREGYLVKKGSVFNTWKPMWVVLLEDGIEFYKKKSDNSPKGMIPLKGSTLTSPCQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DFGKRMFVFKITTTKQQDHFFQAAFLEERDAWVRDIKKAIKCIEGGQKFARKSTRRSIRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 DFGKRMFVFKITTTKQQDHFFQAAFLEERDAWVRDIKKAIKCIEGGQKFARKSTRRSIRL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 PETIDLGALYLSMKDTEKGIKELNLEKDKKIFNHCFTGNCVIDWLVSNQSVRNRQEGLMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 PETIDLGALYLSMKDTEKGIKELNLEKDKKIFNHCFTGNCVIDWLVSNQSVRNRQEGLMI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ASSLLNEGYLQPAGDMSKSAVDGTAENPFLDNPDAFYYFPDSGFFCEENSSDDDVILKEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 ASSLLNEGYLQPAGDMSKSAVDGTAENPFLDNPDAFYYFPDSGFFCEENSSDDDVILKEE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 FRGVIIKQGCLLKQGHRRKNWKVRKFILREDPAYLHYYDPAGAEDPLGAIHLRGCVVTSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 FRGVIIKQGCLLKQGHRRKNWKVRKFILREDPAYLHYYDPAGAEDPLGAIHLRGCVVTSV 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 ESNSNGRKSEEENLFEIITADEVHYFLQAATPKERTEWIRAIQMASRTGK :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 ESNSNGRKSEEENLFEIITADEVHYFLQAATPKERTEWIRAIQMASRTGK 310 320 330 340 350 >>CCDS9782.1 PLEK2 gene_id:26499|Hs108|chr14 (353 aa) initn: 784 init1: 537 opt: 859 Z-score: 965.6 bits: 187.2 E(32554): 1.8e-47 Smith-Waterman score: 859; 38.8% identity (71.1% similar) in 353 aa overlap (1-343:1-350) 10 20 30 40 50 pF1KE0 MEPKRIREGYLVKKGSVFNTWKPMWVVLLEDGIEFYKKKSD---NSPKGMIPLKGSTLTS :: ..::.:::.: . ..:: : .: .. . .:: .. . ::: : : : :.: CCDS97 MEDGVLKEGFLVKRGHIVHNWKARWFILRQNTLVYYKLEGGRRVTPPKGRILLDGCTITC 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 PCQDFGKRMFVFKITTTKQQDHFFQAAFLEERDAWVRDIKKAIKCIEGGQKFARKSTRRS :: .. .: ...:. : . ..:..: ::::::. .: ::. . :. .: : : CCDS97 PCLEYENRPLLIKLKTQTSTEYFLEACSREERDAWAFEITGAIHAGQPGKVQQLHSLRNS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 IRLPETIDLGALYLSMKDTEKGIKEL-NLEKDKKIFNHCFTGNCVIDWLVSNQSVRNRQE ..:: :.: . .:.:.. ::. :.:. . ... : :. ..:::.::. . .: : CCDS97 FKLPPHISLHRIVDKMHDSNTGIRSSPNMEQGST-YKKTFLGSSLVDWLISNSFTASRLE 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 GLMIASSLLNEGYLQPAGDMSKSAV-DGTAENPFLDNPDAFYYFPDSGFFCEENSSDDDV .. .:: :..:..:.:.: : .:. .: . :::. :.: : .: . .. : ... CCDS97 AVTLASMLMEENFLRPVGVRSMGAIRSGDLAEQFLDDSTALYTFAES--YKKKISPKEEI 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 ILKE-EFRGVIIKQGCLLKQGHRRKNWKVRKFILREDPAYLHYYDPAGAED-PLGAIHLR :. :. :...::: : ::::.:::::::.:.::.:::.::::::. :. :.:.. :: CCDS97 SLSTVELSGTVVKQGYLAKQGHKRKNWKVRRFVLRKDPAFLHYYDPSKEENRPVGGFSLR 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 GCVVTSVESNS--NGRKSEEE-NLFEIITADEVHYFLQAATPKERTEWIRAIQMASRTGK : .:...:.:. .: :.. . :::..:: :..::..::.. ::.:::.::. CCDS97 GSLVSALEDNGVPTGVKGNVQGNLFKVITKDDTHYYIQASSKAERAEWIEAIKKLT 300 310 320 330 340 350 350 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 03:07:42 2016 done: Sat Nov 5 03:07:42 2016 Total Scan time: 2.650 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]