FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0783, 352 aa 1>>>pF1KE0783 352 - 352 aa - 352 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.8085+/-0.000297; mu= 5.2689+/- 0.019 mean_var=165.4885+/-35.765, 0's: 0 Z-trim(121.8): 116 B-trim: 2104 in 1/54 Lambda= 0.099699 statistics sampled from 38699 (38849) to 38699 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.791), E-opt: 0.2 (0.455), width: 16 Scan time: 8.970 The best scores are: opt bits E(85289) NP_116244 (OMIM: 608349) hematopoietic SH2 domain- ( 352) 2423 360.1 4.3e-99 NP_001278203 (OMIM: 608349) hematopoietic SH2 doma ( 295) 1927 288.7 1.1e-77 XP_011526691 (OMIM: 608349) PREDICTED: hematopoiet ( 272) 1858 278.7 1e-74 XP_011526689 (OMIM: 608349) PREDICTED: hematopoiet ( 325) 1348 205.4 1.4e-52 XP_011526690 (OMIM: 608349) PREDICTED: hematopoiet ( 325) 1348 205.4 1.4e-52 XP_011526688 (OMIM: 608349) PREDICTED: hematopoiet ( 405) 1348 205.5 1.7e-52 XP_011526692 (OMIM: 608349) PREDICTED: hematopoiet ( 187) 1090 168.1 1.4e-41 XP_016882892 (OMIM: 608349) PREDICTED: hematopoiet ( 218) 1089 168.0 1.7e-41 XP_016882891 (OMIM: 608349) PREDICTED: hematopoiet ( 225) 1089 168.0 1.8e-41 XP_016882893 (OMIM: 608349) PREDICTED: hematopoiet ( 176) 877 137.5 2.2e-32 NP_001154915 (OMIM: 604514) SH2 domain-containing ( 361) 344 61.0 4.6e-09 NP_001154914 (OMIM: 604514) SH2 domain-containing ( 371) 344 61.0 4.7e-09 XP_016858253 (OMIM: 604514) PREDICTED: SH2 domain- ( 385) 344 61.1 4.8e-09 NP_003966 (OMIM: 604514) SH2 domain-containing pro ( 389) 344 61.1 4.9e-09 NP_001154916 (OMIM: 604514) SH2 domain-containing ( 389) 344 61.1 4.9e-09 XP_006711678 (OMIM: 604514) PREDICTED: SH2 domain- ( 395) 344 61.1 4.9e-09 NP_001167631 (OMIM: 614968) SH2 domain-containing ( 409) 273 50.9 6e-06 XP_011542912 (OMIM: 614968) PREDICTED: SH2 domain- ( 427) 273 50.9 6.2e-06 XP_016869218 (OMIM: 614968) PREDICTED: SH2 domain- ( 427) 273 50.9 6.2e-06 NP_001167630 (OMIM: 614968) SH2 domain-containing ( 454) 273 50.9 6.5e-06 NP_071354 (OMIM: 614968) SH2 domain-containing pro ( 454) 273 50.9 6.5e-06 XP_016858255 (OMIM: 604514) PREDICTED: SH2 domain- ( 377) 255 48.2 3.4e-05 XP_016858254 (OMIM: 604514) PREDICTED: SH2 domain- ( 381) 255 48.2 3.4e-05 NP_001154913 (OMIM: 604514) SH2 domain-containing ( 399) 255 48.3 3.6e-05 XP_016858256 (OMIM: 604514) PREDICTED: SH2 domain- ( 309) 253 47.9 3.6e-05 XP_016858252 (OMIM: 604514) PREDICTED: SH2 domain- ( 401) 255 48.3 3.6e-05 XP_016858251 (OMIM: 604514) PREDICTED: SH2 domain- ( 405) 255 48.3 3.6e-05 >>NP_116244 (OMIM: 608349) hematopoietic SH2 domain-cont (352 aa) initn: 2423 init1: 2423 opt: 2423 Z-score: 1900.0 bits: 360.1 E(85289): 4.3e-99 Smith-Waterman score: 2423; 100.0% identity (100.0% similar) in 352 aa overlap (1-352:1-352) 10 20 30 40 50 60 pF1KE0 MTEAGKLPLPLPPRLDWFVHTQMGQLAQDGVPEWFHGAISREDAENLLESQPLGSFLIRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 MTEAGKLPLPLPPRLDWFVHTQMGQLAQDGVPEWFHGAISREDAENLLESQPLGSFLIRV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRREL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 SHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRREL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEEASPKPVLCHQSKERKPSAEMNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 LTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEEASPKPVLCHQSKERKPSAEMNR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ITTKEATSSCPPKSPLGETRQKLWRSLKMLPERGQRVRQQLKSHLATVNLSSLLDVRRST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 ITTKEATSSCPPKSPLGETRQKLWRSLKMLPERGQRVRQQLKSHLATVNLSSLLDVRRST 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 VISGPGTGKGSQDHSGDPTSGDRGYTDPCVATSLKSPSQPQAPKDRKVPTRKAERSVSCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 VISGPGTGKGSQDHSGDPTSGDRGYTDPCVATSLKSPSQPQAPKDRKVPTRKAERSVSCI 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 EVTPGDRSWHQMVVRALSSQESKPEHQGLAEPENDQLPEEYQQPPPFAPGYC :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 EVTPGDRSWHQMVVRALSSQESKPEHQGLAEPENDQLPEEYQQPPPFAPGYC 310 320 330 340 350 >>NP_001278203 (OMIM: 608349) hematopoietic SH2 domain-c (295 aa) initn: 1927 init1: 1927 opt: 1927 Z-score: 1515.5 bits: 288.7 E(85289): 1.1e-77 Smith-Waterman score: 1927; 99.6% identity (100.0% similar) in 281 aa overlap (72-352:15-295) 50 60 70 80 90 100 pF1KE0 EDAENLLESQPLGSFLIRVSHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHTS .::::::::::::::::::::::::::::: NP_001 MRGSRMSQPPQCLRRAQSSCCHFMVKLLDDGTFMIPGEKVAHTS 10 20 30 40 110 120 130 140 150 160 pF1KE0 LDALVTFHQQKPIEPRRELLTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEEASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDALVTFHQQKPIEPRRELLTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEEASP 50 60 70 80 90 100 170 180 190 200 210 220 pF1KE0 KPVLCHQSKERKPSAEMNRITTKEATSSCPPKSPLGETRQKLWRSLKMLPERGQRVRQQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPVLCHQSKERKPSAEMNRITTKEATSSCPPKSPLGETRQKLWRSLKMLPERGQRVRQQL 110 120 130 140 150 160 230 240 250 260 270 280 pF1KE0 KSHLATVNLSSLLDVRRSTVISGPGTGKGSQDHSGDPTSGDRGYTDPCVATSLKSPSQPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSHLATVNLSSLLDVRRSTVISGPGTGKGSQDHSGDPTSGDRGYTDPCVATSLKSPSQPQ 170 180 190 200 210 220 290 300 310 320 330 340 pF1KE0 APKDRKVPTRKAERSVSCIEVTPGDRSWHQMVVRALSSQESKPEHQGLAEPENDQLPEEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APKDRKVPTRKAERSVSCIEVTPGDRSWHQMVVRALSSQESKPEHQGLAEPENDQLPEEY 230 240 250 260 270 280 350 pF1KE0 QQPPPFAPGYC ::::::::::: NP_001 QQPPPFAPGYC 290 >>XP_011526691 (OMIM: 608349) PREDICTED: hematopoietic S (272 aa) initn: 1858 init1: 1858 opt: 1858 Z-score: 1462.3 bits: 278.7 E(85289): 1e-74 Smith-Waterman score: 1858; 100.0% identity (100.0% similar) in 272 aa overlap (81-352:1-272) 60 70 80 90 100 110 pF1KE0 QPLGSFLIRVSHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQ :::::::::::::::::::::::::::::: XP_011 MVKLLDDGTFMIPGEKVAHTSLDALVTFHQ 10 20 30 120 130 140 150 160 170 pF1KE0 QKPIEPRRELLTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEEASPKPVLCHQSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QKPIEPRRELLTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEEASPKPVLCHQSK 40 50 60 70 80 90 180 190 200 210 220 230 pF1KE0 ERKPSAEMNRITTKEATSSCPPKSPLGETRQKLWRSLKMLPERGQRVRQQLKSHLATVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERKPSAEMNRITTKEATSSCPPKSPLGETRQKLWRSLKMLPERGQRVRQQLKSHLATVNL 100 110 120 130 140 150 240 250 260 270 280 290 pF1KE0 SSLLDVRRSTVISGPGTGKGSQDHSGDPTSGDRGYTDPCVATSLKSPSQPQAPKDRKVPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSLLDVRRSTVISGPGTGKGSQDHSGDPTSGDRGYTDPCVATSLKSPSQPQAPKDRKVPT 160 170 180 190 200 210 300 310 320 330 340 350 pF1KE0 RKAERSVSCIEVTPGDRSWHQMVVRALSSQESKPEHQGLAEPENDQLPEEYQQPPPFAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKAERSVSCIEVTPGDRSWHQMVVRALSSQESKPEHQGLAEPENDQLPEEYQQPPPFAPG 220 230 240 250 260 270 pF1KE0 YC :: XP_011 YC >>XP_011526689 (OMIM: 608349) PREDICTED: hematopoietic S (325 aa) initn: 1633 init1: 1335 opt: 1348 Z-score: 1064.8 bits: 205.4 E(85289): 1.4e-52 Smith-Waterman score: 1559; 76.9% identity (81.2% similar) in 325 aa overlap (81-352:1-325) 60 70 80 90 100 110 pF1KE0 QPLGSFLIRVSHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQ :::::::::::::::::::::::::::::: XP_011 MVKLLDDGTFMIPGEKVAHTSLDALVTFHQ 10 20 30 120 130 140 pF1KE0 QKPIEPRRELLTQPCRQ-------------------KDPA-----------NVDYEDLFL ::::::::::::::::. : :: .: . ..: XP_011 QKPIEPRRELLTQPCRRIPQTWITRISSSTPTQWPRKLPARCLPLRSGLPKSVPQNPIYL 40 50 60 70 80 90 150 160 170 pF1KE0 Y---------SNAVAEE------------AACPVSAPE--EASPKPVLCHQSKERKPSAE . :..:. : . :...: .::::::::::::::::::: XP_011 WVYMLPGCLSSQTVSSERLETPSGLFAFASPTPLKGPAILKASPKPVLCHQSKERKPSAE 100 110 120 130 140 150 180 190 200 210 220 230 pF1KE0 MNRITTKEATSSCPPKSPLGETRQKLWRSLKMLPERGQRVRQQLKSHLATVNLSSLLDVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNRITTKEATSSCPPKSPLGETRQKLWRSLKMLPERGQRVRQQLKSHLATVNLSSLLDVR 160 170 180 190 200 210 240 250 260 270 280 290 pF1KE0 RSTVISGPGTGKGSQDHSGDPTSGDRGYTDPCVATSLKSPSQPQAPKDRKVPTRKAERSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSTVISGPGTGKGSQDHSGDPTSGDRGYTDPCVATSLKSPSQPQAPKDRKVPTRKAERSV 220 230 240 250 260 270 300 310 320 330 340 350 pF1KE0 SCIEVTPGDRSWHQMVVRALSSQESKPEHQGLAEPENDQLPEEYQQPPPFAPGYC ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCIEVTPGDRSWHQMVVRALSSQESKPEHQGLAEPENDQLPEEYQQPPPFAPGYC 280 290 300 310 320 >>XP_011526690 (OMIM: 608349) PREDICTED: hematopoietic S (325 aa) initn: 1633 init1: 1335 opt: 1348 Z-score: 1064.8 bits: 205.4 E(85289): 1.4e-52 Smith-Waterman score: 1559; 76.9% identity (81.2% similar) in 325 aa overlap (81-352:1-325) 60 70 80 90 100 110 pF1KE0 QPLGSFLIRVSHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQ :::::::::::::::::::::::::::::: XP_011 MVKLLDDGTFMIPGEKVAHTSLDALVTFHQ 10 20 30 120 130 140 pF1KE0 QKPIEPRRELLTQPCRQ-------------------KDPA-----------NVDYEDLFL ::::::::::::::::. : :: .: . ..: XP_011 QKPIEPRRELLTQPCRRIPQTWITRISSSTPTQWPRKLPARCLPLRSGLPKSVPQNPIYL 40 50 60 70 80 90 150 160 170 pF1KE0 Y---------SNAVAEE------------AACPVSAPE--EASPKPVLCHQSKERKPSAE . :..:. : . :...: .::::::::::::::::::: XP_011 WVYMLPGCLSSQTVSSERLETPSGLFAFASPTPLKGPAILKASPKPVLCHQSKERKPSAE 100 110 120 130 140 150 180 190 200 210 220 230 pF1KE0 MNRITTKEATSSCPPKSPLGETRQKLWRSLKMLPERGQRVRQQLKSHLATVNLSSLLDVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNRITTKEATSSCPPKSPLGETRQKLWRSLKMLPERGQRVRQQLKSHLATVNLSSLLDVR 160 170 180 190 200 210 240 250 260 270 280 290 pF1KE0 RSTVISGPGTGKGSQDHSGDPTSGDRGYTDPCVATSLKSPSQPQAPKDRKVPTRKAERSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSTVISGPGTGKGSQDHSGDPTSGDRGYTDPCVATSLKSPSQPQAPKDRKVPTRKAERSV 220 230 240 250 260 270 300 310 320 330 340 350 pF1KE0 SCIEVTPGDRSWHQMVVRALSSQESKPEHQGLAEPENDQLPEEYQQPPPFAPGYC ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCIEVTPGDRSWHQMVVRALSSQESKPEHQGLAEPENDQLPEEYQQPPPFAPGYC 280 290 300 310 320 >>XP_011526688 (OMIM: 608349) PREDICTED: hematopoietic S (405 aa) initn: 2198 init1: 1335 opt: 1348 Z-score: 1063.5 bits: 205.5 E(85289): 1.7e-52 Smith-Waterman score: 1969; 80.5% identity (84.1% similar) in 384 aa overlap (22-352:22-405) 10 20 30 40 50 60 pF1KE0 MTEAGKLPLPLPPRLDWFVHTQMGQLAQDGVPEWFHGAISREDAENLLESQPLGSFLIRV ::::::::::::::::::::::::::::::::::::::: XP_011 MTEAGKLPLPLPPRLDWFVHTQMGQLAQDGVPEWFHGAISREDAENLLESQPLGSFLIRV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRREL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRREL 70 80 90 100 110 120 130 140 pF1KE0 LTQPCRQ-------------------KDPA-----------NVDYEDLFLY--------- ::::::. : :: .: . ..:. XP_011 LTQPCRRIPQTWITRISSSTPTQWPRKLPARCLPLRSGLPKSVPQNPIYLWVYMLPGCLS 130 140 150 160 170 180 150 160 170 180 pF1KE0 SNAVAEE------------AACPVSAPE--EASPKPVLCHQSKERKPSAEMNRITTKEAT :..:. : . :...: .::::::::::::::::::::::::::::: XP_011 SQTVSSERLETPSGLFAFASPTPLKGPAILKASPKPVLCHQSKERKPSAEMNRITTKEAT 190 200 210 220 230 240 190 200 210 220 230 240 pF1KE0 SSCPPKSPLGETRQKLWRSLKMLPERGQRVRQQLKSHLATVNLSSLLDVRRSTVISGPGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSCPPKSPLGETRQKLWRSLKMLPERGQRVRQQLKSHLATVNLSSLLDVRRSTVISGPGT 250 260 270 280 290 300 250 260 270 280 290 300 pF1KE0 GKGSQDHSGDPTSGDRGYTDPCVATSLKSPSQPQAPKDRKVPTRKAERSVSCIEVTPGDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GKGSQDHSGDPTSGDRGYTDPCVATSLKSPSQPQAPKDRKVPTRKAERSVSCIEVTPGDR 310 320 330 340 350 360 310 320 330 340 350 pF1KE0 SWHQMVVRALSSQESKPEHQGLAEPENDQLPEEYQQPPPFAPGYC ::::::::::::::::::::::::::::::::::::::::::::: XP_011 SWHQMVVRALSSQESKPEHQGLAEPENDQLPEEYQQPPPFAPGYC 370 380 390 400 >>XP_011526692 (OMIM: 608349) PREDICTED: hematopoietic S (187 aa) initn: 1090 init1: 1090 opt: 1090 Z-score: 867.6 bits: 168.1 E(85289): 1.4e-41 Smith-Waterman score: 1090; 97.5% identity (98.8% similar) in 162 aa overlap (1-162:1-162) 10 20 30 40 50 60 pF1KE0 MTEAGKLPLPLPPRLDWFVHTQMGQLAQDGVPEWFHGAISREDAENLLESQPLGSFLIRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTEAGKLPLPLPPRLDWFVHTQMGQLAQDGVPEWFHGAISREDAENLLESQPLGSFLIRV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRREL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRREL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEEASPKPVLCHQSKERKPSAEMNR :::::::::::::::::::::::::::::::::::::: . . XP_011 LTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEERTSQKCSSKSYLLMGLHAPWLP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ITTKEATSSCPPKSPLGETRQKLWRSLKMLPERGQRVRQQLKSHLATVNLSSLLDVRRST XP_011 FQSDCEL >>XP_016882892 (OMIM: 608349) PREDICTED: hematopoietic S (218 aa) initn: 1112 init1: 1089 opt: 1089 Z-score: 865.9 bits: 168.0 E(85289): 1.7e-41 Smith-Waterman score: 1089; 100.0% identity (100.0% similar) in 158 aa overlap (1-158:1-158) 10 20 30 40 50 60 pF1KE0 MTEAGKLPLPLPPRLDWFVHTQMGQLAQDGVPEWFHGAISREDAENLLESQPLGSFLIRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTEAGKLPLPLPPRLDWFVHTQMGQLAQDGVPEWFHGAISREDAENLLESQPLGSFLIRV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRREL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRREL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEEASPKPVLCHQSKERKPSAEMNR :::::::::::::::::::::::::::::::::::::: XP_016 LTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEETESCFVDQAGVEWHSLGSLQPP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ITTKEATSSCPPKSPLGETRQKLWRSLKMLPERGQRVRQQLKSHLATVNLSSLLDVRRST XP_016 PPRFKRFSCLSLLSSWDYRPPQSQSCVTNQRKGSRQQR 190 200 210 >>XP_016882891 (OMIM: 608349) PREDICTED: hematopoietic S (225 aa) initn: 1112 init1: 1089 opt: 1089 Z-score: 865.7 bits: 168.0 E(85289): 1.8e-41 Smith-Waterman score: 1089; 100.0% identity (100.0% similar) in 158 aa overlap (1-158:1-158) 10 20 30 40 50 60 pF1KE0 MTEAGKLPLPLPPRLDWFVHTQMGQLAQDGVPEWFHGAISREDAENLLESQPLGSFLIRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTEAGKLPLPLPPRLDWFVHTQMGQLAQDGVPEWFHGAISREDAENLLESQPLGSFLIRV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRREL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRREL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEEASPKPVLCHQSKERKPSAEMNR :::::::::::::::::::::::::::::::::::::: XP_016 LTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEETESCFVDQAGVEWHSLGSLQPP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ITTKEATSSCPPKSPLGETRQKLWRSLKMLPERGQRVRQQLKSHLATVNLSSLLDVRRST XP_016 PPRFKRFSCLSLLSSWDYRCVLIFVFLVETGFHHVGQTGLKPLTS 190 200 210 220 >>XP_016882893 (OMIM: 608349) PREDICTED: hematopoietic S (176 aa) initn: 901 init1: 877 opt: 877 Z-score: 702.4 bits: 137.5 E(85289): 2.2e-32 Smith-Waterman score: 877; 99.2% identity (100.0% similar) in 127 aa overlap (1-127:1-127) 10 20 30 40 50 60 pF1KE0 MTEAGKLPLPLPPRLDWFVHTQMGQLAQDGVPEWFHGAISREDAENLLESQPLGSFLIRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTEAGKLPLPLPPRLDWFVHTQMGQLAQDGVPEWFHGAISREDAENLLESQPLGSFLIRV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRREL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRREL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEEASPKPVLCHQSKERKPSAEMNR ::::::. XP_016 LTQPCRRIPQTWITRISSSTPTQWPRKLPARCLPLRRPPQSQSCVTNQRKGSRQQR 130 140 150 160 170 352 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 18:40:06 2016 done: Sat Nov 5 18:40:08 2016 Total Scan time: 8.970 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]