FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0787, 353 aa 1>>>pF1KE0787 353 - 353 aa - 353 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9834+/-0.00107; mu= 12.4772+/- 0.064 mean_var=87.0433+/-17.138, 0's: 0 Z-trim(104.7): 75 B-trim: 0 in 0/50 Lambda= 0.137470 statistics sampled from 7957 (8027) to 7957 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.631), E-opt: 0.2 (0.247), width: 16 Scan time: 2.670 The best scores are: opt bits E(32554) CCDS9782.1 PLEK2 gene_id:26499|Hs108|chr14 ( 353) 2335 473.4 1.2e-133 CCDS1887.1 PLEK gene_id:5341|Hs108|chr2 ( 350) 859 180.7 1.6e-45 >>CCDS9782.1 PLEK2 gene_id:26499|Hs108|chr14 (353 aa) initn: 2335 init1: 2335 opt: 2335 Z-score: 2512.7 bits: 473.4 E(32554): 1.2e-133 Smith-Waterman score: 2335; 100.0% identity (100.0% similar) in 353 aa overlap (1-353:1-353) 10 20 30 40 50 60 pF1KE0 MEDGVLKEGFLVKRGHIVHNWKARWFILRQNTLVYYKLEGGRRVTPPKGRILLDGCTITC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 MEDGVLKEGFLVKRGHIVHNWKARWFILRQNTLVYYKLEGGRRVTPPKGRILLDGCTITC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PCLEYENRPLLIKLKTQTSTEYFLEACSREERDAWAFEITGAIHAGQPGKVQQLHSLRNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 PCLEYENRPLLIKLKTQTSTEYFLEACSREERDAWAFEITGAIHAGQPGKVQQLHSLRNS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 FKLPPHISLHRIVDKMHDSNTGIRSSPNMEQGSTYKKTFLGSSLVDWLISNSFTASRLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 FKLPPHISLHRIVDKMHDSNTGIRSSPNMEQGSTYKKTFLGSSLVDWLISNSFTASRLEA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 VTLASMLMEENFLRPVGVRSMGAIRSGDLAEQFLDDSTALYTFAESYKKKISPKEEISLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 VTLASMLMEENFLRPVGVRSMGAIRSGDLAEQFLDDSTALYTFAESYKKKISPKEEISLS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 TVELSGTVVKQGYLAKQGHKRKNWKVRRFVLRKDPAFLHYYDPSKEENRPVGGFSLRGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 TVELSGTVVKQGYLAKQGHKRKNWKVRRFVLRKDPAFLHYYDPSKEENRPVGGFSLRGSL 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 VSALEDNGVPTGVKGNVQGNLFKVITKDDTHYYIQASSKAERAEWIEAIKKLT ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 VSALEDNGVPTGVKGNVQGNLFKVITKDDTHYYIQASSKAERAEWIEAIKKLT 310 320 330 340 350 >>CCDS1887.1 PLEK gene_id:5341|Hs108|chr2 (350 aa) initn: 784 init1: 537 opt: 859 Z-score: 930.7 bits: 180.7 E(32554): 1.6e-45 Smith-Waterman score: 859; 38.8% identity (71.1% similar) in 353 aa overlap (1-350:1-343) 10 20 30 40 50 60 pF1KE0 MEDGVLKEGFLVKRGHIVHNWKARWFILRQNTLVYYKLEGGRRVTPPKGRILLDGCTITC :: ..::.:::.: . ..:: : .: .. . .:: .. . ::: : : : :.: CCDS18 MEPKRIREGYLVKKGSVFNTWKPMWVVLLEDGIEFYKKKSD---NSPKGMIPLKGSTLTS 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 PCLEYENRPLLIKLKTQTSTEYFLEACSREERDAWAFEITGAIHAGQPGKVQQLHSLRNS :: .. .: ...:. : . ..:..: ::::::. .: ::. . :. .: : : CCDS18 PCQDFGKRMFVFKITTTKQQDHFFQAAFLEERDAWVRDIKKAIKCIEGGQKFARKSTRRS 60 70 80 90 100 110 130 140 150 160 170 pF1KE0 FKLPPHISLHRIVDKMHDSNTGIRSSPNMEQGST-YKKTFLGSSLVDWLISNSFTASRLE ..:: :.: . .:.:.. ::. :.:. . ... : :. ..:::.::. . .: : CCDS18 IRLPETIDLGALYLSMKDTEKGIKEL-NLEKDKKIFNHCFTGNCVIDWLVSNQSVRNRQE 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 AVTLASMLMEENFLRPVGVRSMGAIRSGDLAEQFLDDSTALYTFAES--YKKKISPKEEI .. .:: :..:..:.:.: : .:. .: . :::. :.: : .: . .. : ... CCDS18 GLMIASSLLNEGYLQPAGDMSKSAV-DGTAENPFLDNPDAFYYFPDSGFFCEENSSDDDV 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 SLSTVELSGTVVKQGYLAKQGHKRKNWKVRRFVLRKDPAFLHYYDPSKEENRPVGGFSLR :. :. :...::: : ::::.:::::::.:.::.:::.::::::. :. :.:.. :: CCDS18 ILKE-EFRGVIIKQGCLLKQGHRRKNWKVRKFILREDPAYLHYYDPAGAED-PLGAIHLR 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 GSLVSALEDNGVPTGVKGNVQGNLFKVITKDDTHYYIQASSKAERAEWIEAIKKLT : .:...:.:. .: :.. . :::..:: :..::..::.. ::.:::.::. CCDS18 GCVVTSVESNS--NGRKSE-EENLFEIITADEVHYFLQAATPKERTEWIRAIQMASRTGK 300 310 320 330 340 350 353 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 03:08:52 2016 done: Sat Nov 5 03:08:53 2016 Total Scan time: 2.670 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]