Result of FASTA (omim) for
pF1KE0795
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0795, 358 aa
1>>>pF1KE0795 358 - 358 aa - 358 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.2023+/-0.000349; mu= 3.2883+/- 0.022
mean_var=184.1567+/-37.899, 0's: 0 Z-trim(121.1): 206 B-trim: 1729 in 2/55
Lambda= 0.094511
statistics sampled from 36841 (37197) to 36841 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.766), E-opt: 0.2 (0.436), width: 16
Scan time: 9.860
The best scores are: opt bits E(85289)
NP_004243 (OMIM: 604990,612287) Na(+)/H(+) exchang ( 358) 2370 335.1 1.4e-91
NP_001123484 (OMIM: 606553) Na(+)/H(+) exchange re ( 337) 999 148.2 2.6e-35
NP_004776 (OMIM: 606553) Na(+)/H(+) exchange regul ( 326) 998 148.0 2.8e-35
XP_016879384 (OMIM: 606553) PREDICTED: Na(+)/H(+) ( 281) 668 103.0 8.6e-22
NP_001239004 (OMIM: 606553) Na(+)/H(+) exchange re ( 224) 611 95.1 1.6e-19
XP_016879383 (OMIM: 606553) PREDICTED: Na(+)/H(+) ( 372) 610 95.2 2.6e-19
NP_001239002 (OMIM: 606553) Na(+)/H(+) exchange re ( 226) 598 93.4 5.4e-19
NP_001239005 (OMIM: 606553) Na(+)/H(+) exchange re ( 215) 597 93.2 5.7e-19
XP_005255759 (OMIM: 606553) PREDICTED: Na(+)/H(+) ( 342) 594 92.9 1.1e-18
XP_006721044 (OMIM: 606553) PREDICTED: Na(+)/H(+) ( 202) 568 89.2 8.5e-18
NP_001188255 (OMIM: 603831) Na(+)/H(+) exchange re ( 408) 482 77.7 5e-14
NP_079067 (OMIM: 607146) Na(+)/H(+) exchange regul ( 491) 426 70.2 1.1e-11
NP_001161940 (OMIM: 607146) Na(+)/H(+) exchange re ( 505) 426 70.2 1.2e-11
XP_011541307 (OMIM: 607146) PREDICTED: Na(+)/H(+) ( 506) 426 70.2 1.2e-11
XP_016873823 (OMIM: 607146) PREDICTED: Na(+)/H(+) ( 557) 426 70.2 1.3e-11
XP_011541302 (OMIM: 607146) PREDICTED: Na(+)/H(+) ( 571) 426 70.2 1.3e-11
XP_011541304 (OMIM: 607146) PREDICTED: Na(+)/H(+) ( 571) 426 70.2 1.3e-11
XP_011541303 (OMIM: 607146) PREDICTED: Na(+)/H(+) ( 571) 426 70.2 1.3e-11
XP_016856956 (OMIM: 603831) PREDICTED: Na(+)/H(+) ( 312) 313 54.6 3.5e-07
XP_011507920 (OMIM: 603831) PREDICTED: Na(+)/H(+) ( 508) 313 54.8 5.1e-07
XP_011507918 (OMIM: 603831) PREDICTED: Na(+)/H(+) ( 512) 313 54.8 5.1e-07
NP_001188254 (OMIM: 603831) Na(+)/H(+) exchange re ( 519) 313 54.8 5.2e-07
NP_002605 (OMIM: 603831) Na(+)/H(+) exchange regul ( 519) 313 54.8 5.2e-07
XP_016856953 (OMIM: 603831) PREDICTED: Na(+)/H(+) ( 519) 313 54.8 5.2e-07
XP_011507921 (OMIM: 603831) PREDICTED: Na(+)/H(+) ( 409) 302 53.2 1.2e-06
XP_016856954 (OMIM: 603831) PREDICTED: Na(+)/H(+) ( 409) 302 53.2 1.2e-06
XP_016856955 (OMIM: 603831) PREDICTED: Na(+)/H(+) ( 409) 302 53.2 1.2e-06
XP_005265623 (OMIM: 602625) PREDICTED: membrane-as (1479) 270 49.2 6.8e-05
XP_005265622 (OMIM: 602625) PREDICTED: membrane-as (1481) 270 49.2 6.8e-05
XP_011516796 (OMIM: 607084,607928,611383) PREDICTE ( 556) 259 47.4 9e-05
XP_011516793 (OMIM: 607084,607928,611383) PREDICTE ( 571) 259 47.4 9.1e-05
XP_011516794 (OMIM: 607084,607928,611383) PREDICTE ( 571) 259 47.4 9.1e-05
XP_011516791 (OMIM: 607084,607928,611383) PREDICTE ( 577) 259 47.4 9.2e-05
XP_011516790 (OMIM: 607084,607928,611383) PREDICTE ( 837) 259 47.6 0.00012
NP_001166896 (OMIM: 607084,607928,611383) whirlin ( 906) 259 47.6 0.00013
NP_056219 (OMIM: 607084,607928,611383) whirlin iso ( 907) 259 47.6 0.00013
XP_011516788 (OMIM: 607084,607928,611383) PREDICTE ( 917) 259 47.6 0.00013
XP_011516787 (OMIM: 607084,607928,611383) PREDICTE ( 918) 259 47.6 0.00013
XP_011516786 (OMIM: 607084,607928,611383) PREDICTE ( 918) 259 47.6 0.00013
XP_005265625 (OMIM: 602625) PREDICTED: membrane-as (1478) 260 47.9 0.00017
XP_006713473 (OMIM: 602625) PREDICTED: membrane-as (1479) 260 47.9 0.00017
XP_011532538 (OMIM: 602625) PREDICTED: membrane-as (1480) 260 47.9 0.00017
XP_016862987 (OMIM: 602625) PREDICTED: membrane-as (1490) 260 47.9 0.00017
XP_016862986 (OMIM: 602625) PREDICTED: membrane-as (1491) 260 47.9 0.00018
XP_005265621 (OMIM: 602625) PREDICTED: membrane-as (1491) 260 47.9 0.00018
XP_006713472 (OMIM: 602625) PREDICTED: membrane-as (1492) 260 47.9 0.00018
XP_006713471 (OMIM: 602625) PREDICTED: membrane-as (1492) 260 47.9 0.00018
XP_005265620 (OMIM: 602625) PREDICTED: membrane-as (1492) 260 47.9 0.00018
XP_006713470 (OMIM: 602625) PREDICTED: membrane-as (1493) 260 47.9 0.00018
XP_011510811 (OMIM: 601014) PREDICTED: disks large ( 554) 242 45.1 0.00045
>>NP_004243 (OMIM: 604990,612287) Na(+)/H(+) exchange re (358 aa)
initn: 2370 init1: 2370 opt: 2370 Z-score: 1764.9 bits: 335.1 E(85289): 1.4e-91
Smith-Waterman score: 2370; 100.0% identity (100.0% similar) in 358 aa overlap (1-358:1-358)
10 20 30 40 50 60
pF1KE0 MSADAAAGAPLPRLCCLEKGPNGYGFHLHGEKGKLGQYIRLVEPGSPAEKAGLLAGDRLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSADAAAGAPLPRLCCLEKGPNGYGFHLHGEKGKLGQYIRLVEPGSPAEKAGLLAGDRLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 EVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDEQLQKLGVQVREELLRAQEAPGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDEQLQKLGVQVREELLRAQEAPGQA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 EPPAAAEVQGAGNENEPREADKSHPEQRELRPRLCTMKKGPSGYGFNLHSDKSKPGQFIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EPPAAAEVQGAGNENEPREADKSHPEQRELRPRLCTMKKGPSGYGFNLHSDKSKPGQFIR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 SVDPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIRAGGDETKLLVVDRETDEFFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SVDPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIRAGGDETKLLVVDRETDEFFK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KCRVIPSQEHLNGPLPVPFTNGEIQKENSREALAEAALESPRPALVRSASSDTSEELNSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KCRVIPSQEHLNGPLPVPFTNGEIQKENSREALAEAALESPRPALVRSASSDTSEELNSQ
250 260 270 280 290 300
310 320 330 340 350
pF1KE0 DSPPKQDSTAPSSTSSSDPILDFNISLAMAKERAHQKRSSKRAPQMDWSKKNELFSNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DSPPKQDSTAPSSTSSSDPILDFNISLAMAKERAHQKRSSKRAPQMDWSKKNELFSNL
310 320 330 340 350
>>NP_001123484 (OMIM: 606553) Na(+)/H(+) exchange regula (337 aa)
initn: 1083 init1: 966 opt: 999 Z-score: 755.0 bits: 148.2 E(85289): 2.6e-35
Smith-Waterman score: 1104; 52.1% identity (72.0% similar) in 361 aa overlap (6-358:2-337)
10 20 30 40 50
pF1KE0 MSADAAAGAPL-PRLCCLEKGPNGYGFHLHGEKGKLGQYIRLVEPGSPAEKAGLLAGDRL
:: :: :::: : .: .:::::::::::. ::.:: :::::::: :.: :::::
NP_001 MAAPEPLRPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRL
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 VEVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDEQLQKLGVQVREELLRAQEA-PG
::::: ::: :::.:::.::.:. . .:::::: ::::.:.. . ::. ::.. :
NP_001 VEVNGVNVEGETHHQVVQRIKAVEGQTRLLVVDQETDEELRRRQLTCTEEM--AQRGLPP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 QAEP--PAAAEVQGAGNENEPREADKSHPEQRELRPRLCTMKKGPSGYGFNLHSDKSKPG
.: : .. ... .: . : : : :::::::: ..:::.:::::::::::.::
NP_001 AHDPWEPKPDWAHTGSHSSEAGKKDVSGP-LRELRPRLCHLRKGPQGYGFNLHSDKSRPG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 QFIRSVDPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIRAGGDETKLLVVDRETD
:.:::::: ::: ::::::::..:::: .:: .:..::..:.: ::..::::: :::
NP_001 QYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETD
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 EFFKKCRVIPSQEHLNGPLPVPFTNGEIQKENSREALAEAALESPRPALVRSASSDTSEE
: ::. :: :..::..:::: : ::: :: . ..:. .:.
NP_001 EHFKRLRVTPTEEHVEGPLPSPVTNGT------------------SPAQLNGGSACSSR-
240 250 260 270
300 310 320 330 340 350
pF1KE0 LNSQDSPPKQDSTAPSSTSSSDPILDFNISL----AMAKERAHQKRSSKRAPQMDWSKKN
.: : .. .: .:. ..::. . .. : : :::.:. : .::::::::..:
NP_001 ---SDLPGSDKDTEDGSAWKQDPFQESGLHLSPTAAEAKEKARAMRVNKRAPQMDWNRKR
280 290 300 310 320 330
pF1KE0 ELFSNL
:.:::.
NP_001 EIFSNF
>>NP_004776 (OMIM: 606553) Na(+)/H(+) exchange regulator (326 aa)
initn: 1083 init1: 966 opt: 998 Z-score: 754.5 bits: 148.0 E(85289): 2.8e-35
Smith-Waterman score: 1084; 52.1% identity (71.1% similar) in 357 aa overlap (6-358:2-326)
10 20 30 40 50
pF1KE0 MSADAAAGAPL-PRLCCLEKGPNGYGFHLHGEKGKLGQYIRLVEPGSPAEKAGLLAGDRL
:: :: :::: : .: .:::::::::::. ::.:: :::::::: :.: :::::
NP_004 MAAPEPLRPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRL
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 VEVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDEQLQKLGVQVREELLRAQEA-PG
::::: ::: :::.:::.::.:. . .:::::: ::::.:.. . ::. ::.. :
NP_004 VEVNGVNVEGETHHQVVQRIKAVEGQTRLLVVDQETDEELRRRQLTCTEEM--AQRGLPP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 QAEP--PAAAEVQGAGNENEPREADKSHPEQRELRPRLCTMKKGPSGYGFNLHSDKSKPG
.: : .. ... .: . : : : :::::::: ..:::.:::::::::::.::
NP_004 AHDPWEPKPDWAHTGSHSSEAGKKDVSGP-LRELRPRLCHLRKGPQGYGFNLHSDKSRPG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 QFIRSVDPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIRAGGDETKLLVVDRETD
:.:::::: ::: ::::::::..:::: .:: .:..::..:.: ::..::::: :::
NP_004 QYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETD
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 EFFKKCRVIPSQEHLNGPLPVPFTNGEIQKENSREALAEAALESPRPALVRSASSDTSEE
: ::. :: :..::..:::: : ::: :: . ..:. .:.
NP_004 EHFKRLRVTPTEEHVEGPLPSPVTNGT------------------SPAQLNGGSACSSR-
240 250 260 270
300 310 320 330 340 350
pF1KE0 LNSQDSPPKQDSTAPSSTSSSDPILDFNISLAMAKERAHQKRSSKRAPQMDWSKKNELFS
.: : .. .: :. : .. . : :::.:. : .::::::::..: :.::
NP_004 ---SDLPGSDKDTEESG-------LHLSPTAAEAKEKARAMRVNKRAPQMDWNRKREIFS
280 290 300 310 320
pF1KE0 NL
:.
NP_004 NF
>>XP_016879384 (OMIM: 606553) PREDICTED: Na(+)/H(+) exch (281 aa)
initn: 762 init1: 645 opt: 668 Z-score: 512.2 bits: 103.0 E(85289): 8.6e-22
Smith-Waterman score: 773; 46.6% identity (69.5% similar) in 292 aa overlap (74-358:15-281)
50 60 70 80 90 100
pF1KE0 PGSPAEKAGLLAGDRLVEVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDEQLQKLG
.::.::.:. . .:::::: ::::.:..
XP_016 MDACAHRDRQTENLKVVQRIKAVEGQTRLLVVDQETDEELRRRQ
10 20 30 40
110 120 130 140 150 160
pF1KE0 VQVREELLRAQEA-PGQAEP--PAAAEVQGAGNENEPREADKSHPEQRELRPRLCTMKKG
. ::. ::.. : .: : .. ... .: . : : : :::::::: ..::
XP_016 LTCTEEM--AQRGLPPAHDPWEPKPDWAHTGSHSSEAGKKDVSGP-LRELRPRLCHLRKG
50 60 70 80 90 100
170 180 190 200 210 220
pF1KE0 PSGYGFNLHSDKSKPGQFIRSVDPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIR
:.:::::::::::.:::.:::::: ::: ::::::::..:::: .:: .:..::..:.
XP_016 PQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIK
110 120 130 140 150 160
230 240 250 260 270 280
pF1KE0 AGGDETKLLVVDRETDEFFKKCRVIPSQEHLNGPLPVPFTNGEIQKENSREALAEAALES
: ::..::::: :::: ::. :: :..::..:::: : :::
XP_016 AREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGT-----------------
170 180 190 200
290 300 310 320 330
pF1KE0 PRPALVRSASSDTSEELNSQDSPPKQDSTAPSSTSSSDPILDFNISL----AMAKERAHQ
:: . ..:. .:. .: : .. .: .:. ..::. . .. : : :::.:.
XP_016 -SPAQLNGGSACSSR----SDLPGSDKDTEDGSAWKQDPFQESGLHLSPTAAEAKEKARA
210 220 230 240 250
340 350
pF1KE0 KRSSKRAPQMDWSKKNELFSNL
: .::::::::..: :.:::.
XP_016 MRVNKRAPQMDWNRKREIFSNF
260 270 280
>>NP_001239004 (OMIM: 606553) Na(+)/H(+) exchange regula (224 aa)
initn: 677 init1: 560 opt: 611 Z-score: 471.6 bits: 95.1 E(85289): 1.6e-19
Smith-Waterman score: 716; 49.4% identity (70.2% similar) in 245 aa overlap (118-358:5-224)
90 100 110 120 130 140
pF1KE0 LLVVDPETDEQLQKLGVQVREELLRAQEAPGQAEPPAAAEVQGAGNENEPREADKSHPEQ
:.: ::: : :: .. :.. : : :
NP_001 MARSGSATPPARA--PGAPPRSPPQRLDVSGP-L
10 20 30
150 160 170 180 190 200
pF1KE0 RELRPRLCTMKKGPSGYGFNLHSDKSKPGQFIRSVDPDSPAEASGLRAQDRIVEVNGVCM
:::::::: ..:::.:::::::::::.:::.:::::: ::: ::::::::..:::: .
NP_001 RELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNV
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE0 EGKQHGDVVSAIRAGGDETKLLVVDRETDEFFKKCRVIPSQEHLNGPLPVPFTNGEIQKE
:: .:..::..:.: ::..::::: :::: ::. :: :..::..:::: : :::
NP_001 EGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGT----
100 110 120 130 140
270 280 290 300 310 320
pF1KE0 NSREALAEAALESPRPALVRSASSDTSEELNSQDSPPKQDSTAPSSTSSSDPILDFNISL
:: . ..:. .:. .: : .. .: .:. ..::. . .. :
NP_001 --------------SPAQLNGGSACSSR----SDLPGSDKDTEDGSAWKQDPFQESGLHL
150 160 170 180
330 340 350
pF1KE0 ----AMAKERAHQKRSSKRAPQMDWSKKNELFSNL
: :::.:. : .::::::::..: :.:::.
NP_001 SPTAAEAKEKARAMRVNKRAPQMDWNRKREIFSNF
190 200 210 220
>>XP_016879383 (OMIM: 606553) PREDICTED: Na(+)/H(+) exch (372 aa)
initn: 677 init1: 560 opt: 610 Z-score: 467.8 bits: 95.2 E(85289): 2.6e-19
Smith-Waterman score: 696; 49.4% identity (68.9% similar) in 241 aa overlap (118-358:164-372)
90 100 110 120 130 140
pF1KE0 LLVVDPETDEQLQKLGVQVREELLRAQEAPGQAEPPAAAEVQGAGNENEPREADKSHPEQ
:.: ::: : :: .. :.. : : :
XP_016 GGSLGRPESSGHPGRTPATCCHCAAVMARSGSATPPARA--PGAPPRSPPQRLDVSGP-L
140 150 160 170 180 190
150 160 170 180 190 200
pF1KE0 RELRPRLCTMKKGPSGYGFNLHSDKSKPGQFIRSVDPDSPAEASGLRAQDRIVEVNGVCM
:::::::: ..:::.:::::::::::.:::.:::::: ::: ::::::::..:::: .
XP_016 RELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNV
200 210 220 230 240 250
210 220 230 240 250 260
pF1KE0 EGKQHGDVVSAIRAGGDETKLLVVDRETDEFFKKCRVIPSQEHLNGPLPVPFTNGEIQKE
:: .:..::..:.: ::..::::: :::: ::. :: :..::..:::: : :::
XP_016 EGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGT----
260 270 280 290 300
270 280 290 300 310 320
pF1KE0 NSREALAEAALESPRPALVRSASSDTSEELNSQDSPPKQDSTAPSSTSSSDPILDFNISL
:: . ..:. .:. .: : .. .: :. : .. .
XP_016 --------------SPAQLNGGSACSSR----SDLPGSDKDTEESG-------LHLSPTA
310 320 330 340
330 340 350
pF1KE0 AMAKERAHQKRSSKRAPQMDWSKKNELFSNL
: :::.:. : .::::::::..: :.:::.
XP_016 AEAKEKARAMRVNKRAPQMDWNRKREIFSNF
350 360 370
>>NP_001239002 (OMIM: 606553) Na(+)/H(+) exchange regula (226 aa)
initn: 677 init1: 560 opt: 598 Z-score: 461.9 bits: 93.4 E(85289): 5.4e-19
Smith-Waterman score: 703; 49.0% identity (69.6% similar) in 247 aa overlap (118-358:5-226)
90 100 110 120 130 140
pF1KE0 LLVVDPETDEQLQKLGVQVREELLRAQEAPGQAEPPAAAEVQGAGNENEPRE--ADKSHP
:.: ::: : :: .. :.. : : :
NP_001 MARSGSATPPARA--PGAPPRSPPQRLVQDVSGP
10 20 30
150 160 170 180 190 200
pF1KE0 EQRELRPRLCTMKKGPSGYGFNLHSDKSKPGQFIRSVDPDSPAEASGLRAQDRIVEVNGV
:::::::: ..:::.:::::::::::.:::.:::::: ::: ::::::::..::::
NP_001 -LRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQ
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE0 CMEGKQHGDVVSAIRAGGDETKLLVVDRETDEFFKKCRVIPSQEHLNGPLPVPFTNGEIQ
.:: .:..::..:.: ::..::::: :::: ::. :: :..::..:::: : :::
NP_001 NVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGT--
100 110 120 130 140
270 280 290 300 310 320
pF1KE0 KENSREALAEAALESPRPALVRSASSDTSEELNSQDSPPKQDSTAPSSTSSSDPILDFNI
:: . ..:. .:. .: : .. .: .:. ..::. . ..
NP_001 ----------------SPAQLNGGSACSSR----SDLPGSDKDTEDGSAWKQDPFQESGL
150 160 170 180
330 340 350
pF1KE0 SL----AMAKERAHQKRSSKRAPQMDWSKKNELFSNL
: : :::.:. : .::::::::..: :.:::.
NP_001 HLSPTAAEAKEKARAMRVNKRAPQMDWNRKREIFSNF
190 200 210 220
>>NP_001239005 (OMIM: 606553) Na(+)/H(+) exchange regula (215 aa)
initn: 677 init1: 560 opt: 597 Z-score: 461.5 bits: 93.2 E(85289): 5.7e-19
Smith-Waterman score: 683; 49.0% identity (68.3% similar) in 243 aa overlap (118-358:5-215)
90 100 110 120 130 140
pF1KE0 LLVVDPETDEQLQKLGVQVREELLRAQEAPGQAEPPAAAEVQGAGNENEPRE--ADKSHP
:.: ::: : :: .. :.. : : :
NP_001 MARSGSATPPARA--PGAPPRSPPQRLVQDVSGP
10 20 30
150 160 170 180 190 200
pF1KE0 EQRELRPRLCTMKKGPSGYGFNLHSDKSKPGQFIRSVDPDSPAEASGLRAQDRIVEVNGV
:::::::: ..:::.:::::::::::.:::.:::::: ::: ::::::::..::::
NP_001 -LRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQ
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE0 CMEGKQHGDVVSAIRAGGDETKLLVVDRETDEFFKKCRVIPSQEHLNGPLPVPFTNGEIQ
.:: .:..::..:.: ::..::::: :::: ::. :: :..::..:::: : :::
NP_001 NVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGT--
100 110 120 130 140
270 280 290 300 310 320
pF1KE0 KENSREALAEAALESPRPALVRSASSDTSEELNSQDSPPKQDSTAPSSTSSSDPILDFNI
:: . ..:. .:. .: : .. .: :. : ..
NP_001 ----------------SPAQLNGGSACSSR----SDLPGSDKDTEESG-------LHLSP
150 160 170 180
330 340 350
pF1KE0 SLAMAKERAHQKRSSKRAPQMDWSKKNELFSNL
. : :::.:. : .::::::::..: :.:::.
NP_001 TAAEAKEKARAMRVNKRAPQMDWNRKREIFSNF
190 200 210
>>XP_005255759 (OMIM: 606553) PREDICTED: Na(+)/H(+) exch (342 aa)
initn: 560 init1: 560 opt: 594 Z-score: 456.5 bits: 92.9 E(85289): 1.1e-18
Smith-Waterman score: 594; 61.9% identity (79.6% similar) in 147 aa overlap (118-262:164-307)
90 100 110 120 130 140
pF1KE0 LLVVDPETDEQLQKLGVQVREELLRAQEAPGQAEPPAAAEVQGAGNENEPRE--ADKSHP
:.: ::: : :: .. :.. : : :
XP_005 GGSLGRPESSGHPGRTPATCCHCAAVMARSGSATPPARA--PGAPPRSPPQRLVQDVSGP
140 150 160 170 180 190
150 160 170 180 190 200
pF1KE0 EQRELRPRLCTMKKGPSGYGFNLHSDKSKPGQFIRSVDPDSPAEASGLRAQDRIVEVNGV
:::::::: ..:::.:::::::::::.:::.:::::: ::: ::::::::..::::
XP_005 -LRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQ
200 210 220 230 240 250
210 220 230 240 250 260
pF1KE0 CMEGKQHGDVVSAIRAGGDETKLLVVDRETDEFFKKCRVIPSQEHLNGPLPVPFTNGEIQ
.:: .:..::..:.: ::..::::: :::: ::. :: :..::..:::: : :::
XP_005 NVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGTSP
260 270 280 290 300 310
270 280 290 300 310 320
pF1KE0 KENSREALAEAALESPRPALVRSASSDTSEELNSQDSPPKQDSTAPSSTSSSDPILDFNI
XP_005 AQLNGGSACSSRSDLPGSDKDTEEGPPSGVWD
320 330 340
>>XP_006721044 (OMIM: 606553) PREDICTED: Na(+)/H(+) exch (202 aa)
initn: 677 init1: 560 opt: 568 Z-score: 440.5 bits: 89.2 E(85289): 8.5e-18
Smith-Waterman score: 673; 50.5% identity (71.2% similar) in 222 aa overlap (141-358:4-202)
120 130 140 150 160 170
pF1KE0 LRAQEAPGQAEPPAAAEVQGAGNENEPREADKSHPEQRELRPRLCTMKKGPSGYGFNLHS
: : : :::::::: ..:::.::::::::
XP_006 MPEDVSGP-LRELRPRLCHLRKGPQGYGFNLHS
10 20 30
180 190 200 210 220 230
pF1KE0 DKSKPGQFIRSVDPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIRAGGDETKLLV
:::.:::.:::::: ::: ::::::::..:::: .:: .:..::..:.: ::..:::
XP_006 DKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLV
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE0 VDRETDEFFKKCRVIPSQEHLNGPLPVPFTNGEIQKENSREALAEAALESPRPALVRSAS
:: :::: ::. :: :..::..:::: : ::: :: . ..:
XP_006 VDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGT------------------SPAQLNGGS
100 110 120 130
300 310 320 330 340
pF1KE0 SDTSEELNSQDSPPKQDSTAPSSTSSSDPILDFNISL----AMAKERAHQKRSSKRAPQM
. .:. .: : .. .: .:. ..::. . .. : : :::.:. : .::::::
XP_006 ACSSR----SDLPGSDKDTEDGSAWKQDPFQESGLHLSPTAAEAKEKARAMRVNKRAPQM
140 150 160 170 180 190
350
pF1KE0 DWSKKNELFSNL
::..: :.:::.
XP_006 DWNRKREIFSNF
200
358 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 03:11:53 2016 done: Sat Nov 5 03:11:54 2016
Total Scan time: 9.860 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]