FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0796, 424 aa 1>>>pF1KE0796 424 - 424 aa - 424 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.2599+/-0.000588; mu= -11.4302+/- 0.035 mean_var=720.4071+/-160.373, 0's: 0 Z-trim(116.9): 700 B-trim: 0 in 0/58 Lambda= 0.047784 statistics sampled from 27596 (28474) to 27596 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.699), E-opt: 0.2 (0.334), width: 16 Scan time: 8.130 The best scores are: opt bits E(85289) NP_001129025 (OMIM: 606724) MAP kinase-interacting ( 424) 2847 212.2 2e-54 XP_006711063 (OMIM: 606724) PREDICTED: MAP kinase- ( 424) 2847 212.2 2e-54 XP_006711064 (OMIM: 606724) PREDICTED: MAP kinase- ( 418) 2780 207.6 4.8e-53 XP_006711065 (OMIM: 606724) PREDICTED: MAP kinase- ( 418) 2780 207.6 4.8e-53 XP_006711066 (OMIM: 606724) PREDICTED: MAP kinase- ( 418) 2780 207.6 4.8e-53 XP_016858144 (OMIM: 606724) PREDICTED: MAP kinase- ( 412) 2774 207.2 6.4e-53 XP_016858145 (OMIM: 606724) PREDICTED: MAP kinase- ( 412) 2774 207.2 6.4e-53 XP_016858143 (OMIM: 606724) PREDICTED: MAP kinase- ( 427) 2369 179.3 1.7e-44 XP_016858142 (OMIM: 606724) PREDICTED: MAP kinase- ( 427) 2369 179.3 1.7e-44 XP_016858141 (OMIM: 606724) PREDICTED: MAP kinase- ( 427) 2369 179.3 1.7e-44 XP_006711072 (OMIM: 606724) PREDICTED: MAP kinase- ( 369) 2359 178.5 2.5e-44 XP_006711070 (OMIM: 606724) PREDICTED: MAP kinase- ( 369) 2359 178.5 2.5e-44 XP_006711069 (OMIM: 606724) PREDICTED: MAP kinase- ( 369) 2359 178.5 2.5e-44 XP_016858146 (OMIM: 606724) PREDICTED: MAP kinase- ( 369) 2359 178.5 2.5e-44 XP_016858148 (OMIM: 606724) PREDICTED: MAP kinase- ( 347) 2275 172.7 1.3e-42 NP_945324 (OMIM: 606724) MAP kinase-interacting se ( 347) 2275 172.7 1.3e-42 XP_016858151 (OMIM: 606724) PREDICTED: MAP kinase- ( 341) 2208 168.0 3.2e-41 XP_016858150 (OMIM: 606724) PREDICTED: MAP kinase- ( 341) 2208 168.0 3.2e-41 XP_016858149 (OMIM: 606724) PREDICTED: MAP kinase- ( 341) 2208 168.0 3.2e-41 XP_016858152 (OMIM: 606724) PREDICTED: MAP kinase- ( 335) 2202 167.6 4.2e-41 NP_951009 (OMIM: 605069) MAP kinase-interacting se ( 465) 2018 155.1 3.3e-37 XP_006711077 (OMIM: 606724) PREDICTED: MAP kinase- ( 329) 2004 153.9 5.4e-37 XP_006711076 (OMIM: 606724) PREDICTED: MAP kinase- ( 329) 2004 153.9 5.4e-37 XP_016858153 (OMIM: 606724) PREDICTED: MAP kinase- ( 329) 2004 153.9 5.4e-37 XP_006711078 (OMIM: 606724) PREDICTED: MAP kinase- ( 329) 2004 153.9 5.4e-37 NP_060042 (OMIM: 605069) MAP kinase-interacting se ( 414) 1843 143.0 1.3e-33 XP_016858147 (OMIM: 606724) PREDICTED: MAP kinase- ( 350) 1797 139.7 1.1e-32 NP_003675 (OMIM: 606724) MAP kinase-interacting se ( 465) 1794 139.7 1.5e-32 XP_016858154 (OMIM: 606724) PREDICTED: MAP kinase- ( 292) 1787 138.9 1.6e-32 XP_016858155 (OMIM: 606724) PREDICTED: MAP kinase- ( 252) 1432 114.3 3.5e-25 XP_016858156 (OMIM: 606724) PREDICTED: MAP kinase- ( 252) 1432 114.3 3.5e-25 XP_016858157 (OMIM: 606724) PREDICTED: MAP kinase- ( 243) 933 79.9 7.7e-15 NP_003659 (OMIM: 606723) MAP kinase-activated prot ( 471) 527 52.4 2.9e-06 NP_620777 (OMIM: 606723) MAP kinase-activated prot ( 473) 527 52.4 2.9e-06 XP_016875620 (OMIM: 606723) PREDICTED: MAP kinase- ( 378) 517 51.5 4.2e-06 XP_016875619 (OMIM: 606723) PREDICTED: MAP kinase- ( 380) 517 51.5 4.2e-06 XP_016875618 (OMIM: 606723) PREDICTED: MAP kinase- ( 380) 517 51.5 4.2e-06 XP_016875617 (OMIM: 606723) PREDICTED: MAP kinase- ( 386) 517 51.5 4.3e-06 XP_016875616 (OMIM: 606723) PREDICTED: MAP kinase- ( 386) 517 51.5 4.3e-06 XP_016875614 (OMIM: 606723) PREDICTED: MAP kinase- ( 405) 517 51.6 4.4e-06 XP_016874016 (OMIM: 603606) PREDICTED: ribosomal p ( 398) 408 44.0 0.00079 NP_001287731 (OMIM: 603606) ribosomal protein S6 k ( 765) 410 44.6 0.001 NP_001305290 (OMIM: 603606) ribosomal protein S6 k ( 709) 408 44.4 0.0011 XP_005274437 (OMIM: 603606) PREDICTED: ribosomal p ( 717) 408 44.4 0.0011 NP_003933 (OMIM: 603606) ribosomal protein S6 kina ( 772) 408 44.5 0.0011 NP_001006945 (OMIM: 603606) ribosomal protein S6 k ( 766) 405 44.3 0.0013 XP_016873653 (OMIM: 607670) PREDICTED: serine/thre ( 378) 391 42.8 0.0017 XP_016873652 (OMIM: 607670) PREDICTED: serine/thre ( 378) 391 42.8 0.0017 XP_016873651 (OMIM: 607670) PREDICTED: serine/thre ( 378) 391 42.8 0.0017 XP_016873650 (OMIM: 607670) PREDICTED: serine/thre ( 419) 391 42.9 0.0018 >>NP_001129025 (OMIM: 606724) MAP kinase-interacting ser (424 aa) initn: 2847 init1: 2847 opt: 2847 Z-score: 1098.1 bits: 212.2 E(85289): 2e-54 Smith-Waterman score: 2847; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424) 10 20 30 40 50 60 pF1KE0 MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKGIAHRDLKPENILCES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKGIAHRDLKPENILCES 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 CDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 HISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 AAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSP 370 380 390 400 410 420 pF1KE0 PTAL :::: NP_001 PTAL >>XP_006711063 (OMIM: 606724) PREDICTED: MAP kinase-inte (424 aa) initn: 2847 init1: 2847 opt: 2847 Z-score: 1098.1 bits: 212.2 E(85289): 2e-54 Smith-Waterman score: 2847; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424) 10 20 30 40 50 60 pF1KE0 MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKGIAHRDLKPENILCES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKGIAHRDLKPENILCES 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 CDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 HISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 AAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSP 370 380 390 400 410 420 pF1KE0 PTAL :::: XP_006 PTAL >>XP_006711064 (OMIM: 606724) PREDICTED: MAP kinase-inte (418 aa) initn: 2780 init1: 2780 opt: 2780 Z-score: 1073.2 bits: 207.6 E(85289): 4.8e-53 Smith-Waterman score: 2780; 100.0% identity (100.0% similar) in 413 aa overlap (12-424:6-418) 10 20 30 40 50 60 pF1KE0 MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY ::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MQNIPEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKGIAHRDLKPENILCES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKGIAHRDLKPENILCES 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 PEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKR 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE0 CDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWA 240 250 260 270 280 290 310 320 330 340 350 360 pF1KE0 HISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLF 300 310 320 330 340 350 370 380 390 400 410 420 pF1KE0 AAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSP 360 370 380 390 400 410 pF1KE0 PTAL :::: XP_006 PTAL >>XP_006711065 (OMIM: 606724) PREDICTED: MAP kinase-inte (418 aa) initn: 2780 init1: 2780 opt: 2780 Z-score: 1073.2 bits: 207.6 E(85289): 4.8e-53 Smith-Waterman score: 2780; 100.0% identity (100.0% similar) in 413 aa overlap (12-424:6-418) 10 20 30 40 50 60 pF1KE0 MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY ::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MQNIPEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKGIAHRDLKPENILCES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKGIAHRDLKPENILCES 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 PEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKR 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE0 CDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWA 240 250 260 270 280 290 310 320 330 340 350 360 pF1KE0 HISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLF 300 310 320 330 340 350 370 380 390 400 410 420 pF1KE0 AAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSP 360 370 380 390 400 410 pF1KE0 PTAL :::: XP_006 PTAL >>XP_006711066 (OMIM: 606724) PREDICTED: MAP kinase-inte (418 aa) initn: 2780 init1: 2780 opt: 2780 Z-score: 1073.2 bits: 207.6 E(85289): 4.8e-53 Smith-Waterman score: 2780; 100.0% identity (100.0% similar) in 413 aa overlap (12-424:6-418) 10 20 30 40 50 60 pF1KE0 MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY ::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MQNIPEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKGIAHRDLKPENILCES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKGIAHRDLKPENILCES 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 PEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKR 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE0 CDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWA 240 250 260 270 280 290 310 320 330 340 350 360 pF1KE0 HISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLF 300 310 320 330 340 350 370 380 390 400 410 420 pF1KE0 AAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSP 360 370 380 390 400 410 pF1KE0 PTAL :::: XP_006 PTAL >>XP_016858144 (OMIM: 606724) PREDICTED: MAP kinase-inte (412 aa) initn: 2774 init1: 2774 opt: 2774 Z-score: 1071.1 bits: 207.2 E(85289): 6.4e-53 Smith-Waterman score: 2774; 100.0% identity (100.0% similar) in 412 aa overlap (13-424:1-412) 10 20 30 40 50 60 pF1KE0 MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY 10 20 30 40 70 80 90 100 110 120 pF1KE0 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKGIAHRDLKPENILCES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKGIAHRDLKPENILCES 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE0 PEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKR 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE0 CDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWA 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE0 HISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLF 290 300 310 320 330 340 370 380 390 400 410 420 pF1KE0 AAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSP 350 360 370 380 390 400 pF1KE0 PTAL :::: XP_016 PTAL 410 >>XP_016858145 (OMIM: 606724) PREDICTED: MAP kinase-inte (412 aa) initn: 2774 init1: 2774 opt: 2774 Z-score: 1071.1 bits: 207.2 E(85289): 6.4e-53 Smith-Waterman score: 2774; 100.0% identity (100.0% similar) in 412 aa overlap (13-424:1-412) 10 20 30 40 50 60 pF1KE0 MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY 10 20 30 40 70 80 90 100 110 120 pF1KE0 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKGIAHRDLKPENILCES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKGIAHRDLKPENILCES 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE0 PEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKR 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE0 CDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWA 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE0 HISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLF 290 300 310 320 330 340 370 380 390 400 410 420 pF1KE0 AAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSP 350 360 370 380 390 400 pF1KE0 PTAL :::: XP_016 PTAL 410 >>XP_016858143 (OMIM: 606724) PREDICTED: MAP kinase-inte (427 aa) initn: 2354 init1: 2354 opt: 2369 Z-score: 920.0 bits: 179.3 E(85289): 1.7e-44 Smith-Waterman score: 2369; 89.3% identity (93.8% similar) in 401 aa overlap (26-424:29-427) 10 20 30 40 50 pF1KE0 MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLP--GKFEDMYKLTSELL ....::.. .: :: .. . :... XP_016 MPPDPLRREWAFPLNGQRTSFHFKSSQKKKKEKKKKTPTTKSLCLLKRWAVANPFPSQMV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 GEGAYAKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFE :. . :: : .: ..:::::::::::::::::::::::::::::::::::::: XP_016 -TGGGRRSGGAGPLTPCQE-SLKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFE 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 DDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKGIAHRDLKPEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKGIAHRDLKPEN 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 ILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQAT 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 FYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFP 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 DKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTM 300 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 DLTLFAAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLTLFAAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRG 360 370 380 390 400 410 420 pF1KE0 EDRSPPTAL ::::::::: XP_016 EDRSPPTAL 420 >>XP_016858142 (OMIM: 606724) PREDICTED: MAP kinase-inte (427 aa) initn: 2354 init1: 2354 opt: 2369 Z-score: 920.0 bits: 179.3 E(85289): 1.7e-44 Smith-Waterman score: 2369; 89.3% identity (93.8% similar) in 401 aa overlap (26-424:29-427) 10 20 30 40 50 pF1KE0 MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLP--GKFEDMYKLTSELL ....::.. .: :: .. . :... XP_016 MPPDPLRREWAFPLNGQRTSFHFKSSQKKKKEKKKKTPTTKSLCLLKRWAVANPFPSQMV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 GEGAYAKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFE :. . :: : .: ..:::::::::::::::::::::::::::::::::::::: XP_016 -TGGGRRSGGAGPLTPCQE-SLKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFE 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 DDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKGIAHRDLKPEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKGIAHRDLKPEN 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 ILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQAT 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 FYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFP 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 DKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTM 300 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 DLTLFAAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLTLFAAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRG 360 370 380 390 400 410 420 pF1KE0 EDRSPPTAL ::::::::: XP_016 EDRSPPTAL 420 >>XP_016858141 (OMIM: 606724) PREDICTED: MAP kinase-inte (427 aa) initn: 2354 init1: 2354 opt: 2369 Z-score: 920.0 bits: 179.3 E(85289): 1.7e-44 Smith-Waterman score: 2369; 89.3% identity (93.8% similar) in 401 aa overlap (26-424:29-427) 10 20 30 40 50 pF1KE0 MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLP--GKFEDMYKLTSELL ....::.. .: :: .. . :... XP_016 MPPDPLRREWAFPLNGQRTSFHFKSSQKKKKEKKKKTPTTKSLCLLKRWAVANPFPSQMV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 GEGAYAKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFE :. . :: : .: ..:::::::::::::::::::::::::::::::::::::: XP_016 -TGGGRRSGGAGPLTPCQE-SLKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFE 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 DDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKGIAHRDLKPEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKGIAHRDLKPEN 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 ILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQAT 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 FYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFP 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 DKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTM 300 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 DLTLFAAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLTLFAAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRG 360 370 380 390 400 410 420 pF1KE0 EDRSPPTAL ::::::::: XP_016 EDRSPPTAL 420 424 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 21:29:33 2016 done: Sat Nov 5 21:29:35 2016 Total Scan time: 8.130 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]