FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0803, 312 aa 1>>>pF1KE0803 312 - 312 aa - 312 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.5210+/-0.000305; mu= 20.7226+/- 0.019 mean_var=73.7154+/-16.767, 0's: 0 Z-trim(117.5): 144 B-trim: 1721 in 1/48 Lambda= 0.149381 statistics sampled from 29418 (29624) to 29418 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.347), width: 16 Scan time: 7.770 The best scores are: opt bits E(85289) NP_001034254 (OMIM: 607232) mas-related G-protein ( 312) 2143 470.7 1.7e-132 XP_011518184 (OMIM: 607229) PREDICTED: mas-related ( 322) 665 152.2 1.3e-36 NP_473372 (OMIM: 607229) mas-related G-protein cou ( 322) 665 152.2 1.3e-36 NP_671732 (OMIM: 607227) mas-related G-protein cou ( 322) 657 150.5 4.3e-36 NP_001290544 (OMIM: 607228) mas-related G-protein ( 330) 649 148.8 1.5e-35 NP_473371 (OMIM: 607228) mas-related G-protein cou ( 330) 649 148.8 1.5e-35 NP_944605 (OMIM: 607231) mas-related G-protein cou ( 321) 642 147.2 4.1e-35 NP_473373 (OMIM: 607230) mas-related G-protein cou ( 322) 634 145.5 1.3e-34 NP_001157849 (OMIM: 607234) mas-related G-protein ( 289) 595 137.1 4.2e-32 XP_016872659 (OMIM: 607233) PREDICTED: mas-related ( 343) 551 127.7 3.4e-29 NP_001091985 (OMIM: 607233) mas-related G-protein ( 343) 551 127.7 3.4e-29 NP_659452 (OMIM: 607233) mas-related G-protein cou ( 343) 551 127.7 3.4e-29 NP_002368 (OMIM: 165180) proto-oncogene Mas [Homo ( 325) 495 115.6 1.4e-25 NP_443199 (OMIM: 607235) mas-related G-protein cou ( 378) 473 110.9 4.2e-24 NP_001313404 (OMIM: 605246) C3a anaphylatoxin chem ( 482) 196 51.3 4.6e-06 NP_004045 (OMIM: 605246) C3a anaphylatoxin chemota ( 482) 196 51.3 4.6e-06 NP_001313406 (OMIM: 605246) C3a anaphylatoxin chem ( 482) 196 51.3 4.6e-06 NP_005284 (OMIM: 601908) G-protein coupled recepto ( 358) 193 50.5 5.9e-06 NP_001727 (OMIM: 113995) C5a anaphylatoxin chemota ( 350) 188 49.4 1.2e-05 NP_003941 (OMIM: 602779) proteinase-activated rece ( 385) 183 48.4 2.7e-05 XP_011525038 (OMIM: 609949) PREDICTED: C5a anaphyl ( 337) 177 47.0 6.2e-05 NP_001258679 (OMIM: 609949) C5a anaphylatoxin chem ( 337) 177 47.0 6.2e-05 NP_060955 (OMIM: 609949) C5a anaphylatoxin chemota ( 337) 177 47.0 6.2e-05 NP_001258678 (OMIM: 609949) C5a anaphylatoxin chem ( 337) 177 47.0 6.2e-05 NP_005294 (OMIM: 603820) free fatty acid receptor ( 300) 173 46.1 0.0001 NP_001180235 (OMIM: 136537) fMet-Leu-Phe receptor ( 350) 160 43.4 0.0008 NP_002020 (OMIM: 136537) fMet-Leu-Phe receptor [Ho ( 350) 160 43.4 0.0008 NP_002021 (OMIM: 136539) N-formyl peptide receptor ( 353) 157 42.8 0.0013 XP_011524989 (OMIM: 136539) PREDICTED: N-formyl pe ( 353) 157 42.8 0.0013 XP_016874309 (OMIM: 602351) PREDICTED: chemokine-l ( 371) 156 42.6 0.0015 NP_004063 (OMIM: 602351) chemokine-like receptor 1 ( 371) 156 42.6 0.0015 NP_001135815 (OMIM: 602351) chemokine-like recepto ( 373) 156 42.6 0.0015 NP_001135816 (OMIM: 602351) chemokine-like recepto ( 373) 156 42.6 0.0015 NP_001135817 (OMIM: 602351) chemokine-like recepto ( 373) 156 42.6 0.0015 NP_005290 (OMIM: 602043) 12-(S)-hydroxy-5,8,10,14- ( 319) 154 42.1 0.0018 NP_001005738 (OMIM: 136538) N-formyl peptide recep ( 351) 153 41.9 0.0023 NP_001453 (OMIM: 136538) N-formyl peptide receptor ( 351) 153 41.9 0.0023 XP_016882031 (OMIM: 136538) PREDICTED: N-formyl pe ( 351) 153 41.9 0.0023 XP_006723183 (OMIM: 136538) PREDICTED: N-formyl pe ( 351) 153 41.9 0.0023 NP_001171147 (OMIM: 601404) ovarian cancer G-prote ( 365) 151 41.5 0.0032 NP_003476 (OMIM: 601404) ovarian cancer G-protein ( 365) 151 41.5 0.0032 XP_005268167 (OMIM: 601404) PREDICTED: ovarian can ( 375) 151 41.5 0.0032 XP_011535500 (OMIM: 601404) PREDICTED: ovarian can ( 375) 151 41.5 0.0032 XP_005268168 (OMIM: 601404) PREDICTED: ovarian can ( 375) 151 41.5 0.0032 XP_011535501 (OMIM: 601404) PREDICTED: ovarian can ( 375) 151 41.5 0.0032 XP_006720325 (OMIM: 601404) PREDICTED: ovarian can ( 375) 151 41.5 0.0032 XP_011535498 (OMIM: 601404) PREDICTED: ovarian can ( 375) 151 41.5 0.0032 XP_005268169 (OMIM: 601404) PREDICTED: ovarian can ( 375) 151 41.5 0.0032 XP_011535499 (OMIM: 601404) PREDICTED: ovarian can ( 375) 151 41.5 0.0032 NP_005289 (OMIM: 602174) probable G-protein couple ( 361) 150 41.3 0.0036 >>NP_001034254 (OMIM: 607232) mas-related G-protein coup (312 aa) initn: 2143 init1: 2143 opt: 2143 Z-score: 2499.9 bits: 470.7 E(85289): 1.7e-132 Smith-Waterman score: 2143; 100.0% identity (100.0% similar) in 312 aa overlap (1-312:1-312) 10 20 30 40 50 60 pF1KE0 MMEPREAGQHVGAANGAQEDVAFNLIILSLTEGLGLGGLLGNGAVLWLLSSNVYRNPFAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MMEPREAGQHVGAANGAQEDVAFNLIILSLTEGLGLGGLLGNGAVLWLLSSNVYRNPFAI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 YLLDVACADLIFLGCHMVAIVPDLLQGRLDFPGFVQTSLATLRFFCYIVGLSLLAAVSVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLLDVACADLIFLGCHMVAIVPDLLQGRLDFPGFVQTSLATLRFFCYIVGLSLLAAVSVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 QCLAALFPAWYSCRRPRHLTTCVCALTWALCLLLHLLLSGACTQFFGEPSRHLCRTLWLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QCLAALFPAWYSCRRPRHLTTCVCALTWALCLLLHLLLSGACTQFFGEPSRHLCRTLWLV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 AAVLLALLCCTMCGASLMLLLRVERGPQRPPPRGFPGLILLTVLLFLFCGLPFGIYWLSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAVLLALLCCTMCGASLMLLLRVERGPQRPPPRGFPGLILLTVLLFLFCGLPFGIYWLSR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 NLLWYIPHYFYHFSFLMAAVHCAAKPVVYFCLGSAQGRRLPLRLVLQRALGDEAELGAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLLWYIPHYFYHFSFLMAAVHCAAKPVVYFCLGSAQGRRLPLRLVLQRALGDEAELGAVR 250 260 270 280 290 300 310 pF1KE0 ETSRRGLVDIAA :::::::::::: NP_001 ETSRRGLVDIAA 310 >>XP_011518184 (OMIM: 607229) PREDICTED: mas-related G-p (322 aa) initn: 568 init1: 411 opt: 665 Z-score: 778.2 bits: 152.2 E(85289): 1.3e-36 Smith-Waterman score: 665; 39.1% identity (67.3% similar) in 297 aa overlap (8-296:9-301) 10 20 30 40 50 pF1KE0 MMEPREAGQHVGAANGAQEDVAFN--LIILSLTEGLGLGGLLGNGAVLWLLSSNVYRNP : .. :: .: .. : . .:: ..: .: ::..:::::. . :: XP_011 MDSTIPVLGTELTPINGREETPCYKQTLSFTGLTCIVSLVALTGNAVVLWLLGCRMRRNA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 FAIYLLDVACADLIFLGCHMVAIVPDLLQGRLDFPGFVQTSLATLRFFCYIVGLSLLAAV .::.:... ::..::. :.. :.. : : .. :. . : :..:::.:.:. XP_011 VSIYILNLVAADFLFLSGHIICSPLRLINIR--HP--ISKILSPVMTFPYFIGLSMLSAI 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 SVEQCLAALFPAWYSCRRPRHLTTCVCALTWALCLLLHLLLSGACTQFFGEPSRHLCRTL :.:.::. :.: :: :::::.:.. .:.: ::: :: .: : .:. . :.: XP_011 STERCLSILWPIWYHCRRPRYLSSVMCVLLWALSLLRSILEWMFCDFLFSGANSVWCETS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 WLVAAVLLALLCCTMCGASLMLLLRVERGPQRPPPRGFPGLILLTVLLFLFCGLPFGIYW ... . :..:: ..::.::.::.:. : .. : . ::::::.::.::::::: : XP_011 DFITIAWLVFLCVVLCGSSLVLLVRILCGSRKMPLTRLYVTILLTVLVFLLCGLPFGIQW 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 --LSR-NLLWYIPHYFYHF-SFLMAAVHCAAKPVVYFCLGSAQGR--RLPLRLVLQRALG .:: .: : . :. :....:.. .:.:..:: .:: . : : :.::::::: XP_011 ALFSRIHLDWKVLFCHVHLVSIFLSALNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQ 240 250 260 270 280 290 300 310 pF1KE0 DEAELGAVRETSRRGLVDIAA : :. XP_011 DTPEVDEGGGWLPQETLELSGSRLEQ 300 310 320 >>NP_473372 (OMIM: 607229) mas-related G-protein coupled (322 aa) initn: 568 init1: 411 opt: 665 Z-score: 778.2 bits: 152.2 E(85289): 1.3e-36 Smith-Waterman score: 665; 39.1% identity (67.3% similar) in 297 aa overlap (8-296:9-301) 10 20 30 40 50 pF1KE0 MMEPREAGQHVGAANGAQEDVAFN--LIILSLTEGLGLGGLLGNGAVLWLLSSNVYRNP : .. :: .: .. : . .:: ..: .: ::..:::::. . :: NP_473 MDSTIPVLGTELTPINGREETPCYKQTLSFTGLTCIVSLVALTGNAVVLWLLGCRMRRNA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 FAIYLLDVACADLIFLGCHMVAIVPDLLQGRLDFPGFVQTSLATLRFFCYIVGLSLLAAV .::.:... ::..::. :.. :.. : : .. :. . : :..:::.:.:. NP_473 VSIYILNLVAADFLFLSGHIICSPLRLINIR--HP--ISKILSPVMTFPYFIGLSMLSAI 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 SVEQCLAALFPAWYSCRRPRHLTTCVCALTWALCLLLHLLLSGACTQFFGEPSRHLCRTL :.:.::. :.: :: :::::.:.. .:.: ::: :: .: : .:. . :.: NP_473 STERCLSILWPIWYHCRRPRYLSSVMCVLLWALSLLRSILEWMFCDFLFSGANSVWCETS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 WLVAAVLLALLCCTMCGASLMLLLRVERGPQRPPPRGFPGLILLTVLLFLFCGLPFGIYW ... . :..:: ..::.::.::.:. : .. : . ::::::.::.::::::: : NP_473 DFITIAWLVFLCVVLCGSSLVLLVRILCGSRKMPLTRLYVTILLTVLVFLLCGLPFGIQW 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 --LSR-NLLWYIPHYFYHF-SFLMAAVHCAAKPVVYFCLGSAQGR--RLPLRLVLQRALG .:: .: : . :. :....:.. .:.:..:: .:: . : : :.::::::: NP_473 ALFSRIHLDWKVLFCHVHLVSIFLSALNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQ 240 250 260 270 280 290 300 310 pF1KE0 DEAELGAVRETSRRGLVDIAA : :. NP_473 DTPEVDEGGGWLPQETLELSGSRLEQ 300 310 320 >>NP_671732 (OMIM: 607227) mas-related G-protein coupled (322 aa) initn: 593 init1: 396 opt: 657 Z-score: 768.9 bits: 150.5 E(85289): 4.3e-36 Smith-Waterman score: 657; 39.4% identity (68.8% similar) in 292 aa overlap (15-296:16-301) 10 20 30 40 50 pF1KE0 MMEPREAGQHVGAANGAQEDVAFN--LIILSLTEGLGLGGLLGNGAVLWLLSSNVYRNP ::..: . .. : . :: ..: :: ::..:::::. . :: NP_671 MDPTISTLDTELTPINGTEETLCYKQTLSLTVLTCIVSLVGLTGNAVVLWLLGCRMRRNA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 FAIYLLDVACADLIFLGCHMVAIVPDLLQGRLDFPGFVQTSLATLRFFCYIVGLSLLAAV :.::.:..: ::..::. ... : . ...: .. : . .: :..:::.:.:: NP_671 FSIYILNLAAADFLFLSGRLIYS----LLSFISIPHTISKILYPVMMFSYFAGLSFLSAV 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 SVEQCLAALFPAWYSCRRPRHLTTCVCALTWALCLLLHLLLSGACTQFFGEPSRHLCRTL :.:.::..:.: :: :.:: ::.. ::.: ::: :: .: : .:. . :.: NP_671 STERCLSVLWPIWYRCHRPTHLSAVVCVLLWALSLLRSILEWMLCGFLFSGADSAWCQTS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 WLVAAVLLALLCCTMCGASLMLLLRVERGPQRPPPRGFPGLILLTVLLFLFCGLPFGIYW ..... : .:: ..::.::.::.:. : .. : . ::::::.::.::::::: . NP_671 DFITVAWLIFLCVVLCGSSLVLLIRILCGSRKIPLTRLYVTILLTVLVFLLCGLPFGIQF 180 190 200 210 220 230 240 250 260 270 280 pF1KE0 LSRNLLW-YIPH--YFYHF---SFLMAAVHCAAKPVVYFCLGSAQGR--RLPLRLVLQRA . .:: .. . : : :....:.. .:.:..:: .:: . : : :.:::::: NP_671 FL--FLWIHVDREVLFCHVHLVSIFLSALNSSANPIIYFFVGSFRQRQNRQNLKLVLQRA 240 250 260 270 280 290 290 300 310 pF1KE0 LGDEAELGAVRETSRRGLVDIAA : : .:. NP_671 LQDASEVDEGGGQLPEEILELSGSRLEQ 300 310 320 >>NP_001290544 (OMIM: 607228) mas-related G-protein coup (330 aa) initn: 664 init1: 548 opt: 649 Z-score: 759.5 bits: 148.8 E(85289): 1.5e-35 Smith-Waterman score: 649; 39.2% identity (66.8% similar) in 301 aa overlap (25-311:31-325) 10 20 30 40 50 pF1KE0 MMEPREAGQHVGAANGAQEDVAFNLIILSLTEGLGLGGLLGNGAVLWLLSSNVY :: . : ..: ::.::: :::::. . NP_001 MDPTTPAWGTESTTVNGNDQALLLLCGKETLIPVFLILFIALVGLVGNGFVLWLLGFRMR 10 20 30 40 50 60 60 70 80 90 100 pF1KE0 RNPFAIYLLDVACADLIFLGCHMVAIVPDLLQG-----RLDFPGFVQTSLATLRFFC-YI :: :..:.:..: ::..:: : .. :.. ..::.: : .. : :. NP_001 RNAFSVYVLSLAGADFLFL-CFQIINCLVYLSNFFCSISINFPSFFTTVMT-----CAYL 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 VGLSLLAAVSVEQCLAALFPAWYSCRRPRHLTTCVCALTWALCLLLHLLLSGACTQFFGE .:::.:..::.:.::..:.: :: :::::::.. ::.: ::: ::: .: . : .:.. NP_001 AGLSMLSTVSTERCLSVLWPIWYRCRRPRHLSAVVCVLLWALSLLLSILEGKFCGFLFSD 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 PSRHLCRTLWLVAAVLLALLCCTMCGASLMLLLRVERGPQRPPPRGFPGLILLTVLLFLF . :.:. ...:. : .: ..::.:: ::.:. : . : . ::::::.::. NP_001 GDSGWCQTFDFITAAWLIFLFMVLCGSSLALLVRILCGSRGLPLTRLYLTILLTVLVFLL 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 CGLPFGIYWLSRNLLWYIPHYFY-HF---SFLMAAVHCAAKPVVYFCLGSAQGR-RL--P ::::::: :. .: .. :. : ...... .:.:..:: .:: . . :: : NP_001 CGLPFGIQWFLILWIWKDSDVLFCHIHPVSVVLSSLNSSANPIIYFFVGSFRKQWRLQQP 240 250 260 270 280 290 290 300 310 pF1KE0 -LRLVLQRALGDEAELGAVRETSRRGLVDIAA :.:.::::: : ::. . :.: ... NP_001 ILKLALQRALQDIAEVDHSEGCFRQGTPEMSRSSLV 300 310 320 330 >>NP_473371 (OMIM: 607228) mas-related G-protein coupled (330 aa) initn: 664 init1: 548 opt: 649 Z-score: 759.5 bits: 148.8 E(85289): 1.5e-35 Smith-Waterman score: 649; 39.2% identity (66.8% similar) in 301 aa overlap (25-311:31-325) 10 20 30 40 50 pF1KE0 MMEPREAGQHVGAANGAQEDVAFNLIILSLTEGLGLGGLLGNGAVLWLLSSNVY :: . : ..: ::.::: :::::. . NP_473 MDPTTPAWGTESTTVNGNDQALLLLCGKETLIPVFLILFIALVGLVGNGFVLWLLGFRMR 10 20 30 40 50 60 60 70 80 90 100 pF1KE0 RNPFAIYLLDVACADLIFLGCHMVAIVPDLLQG-----RLDFPGFVQTSLATLRFFC-YI :: :..:.:..: ::..:: : .. :.. ..::.: : .. : :. NP_473 RNAFSVYVLSLAGADFLFL-CFQIINCLVYLSNFFCSISINFPSFFTTVMT-----CAYL 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 VGLSLLAAVSVEQCLAALFPAWYSCRRPRHLTTCVCALTWALCLLLHLLLSGACTQFFGE .:::.:..::.:.::..:.: :: :::::::.. ::.: ::: ::: .: . : .:.. NP_473 AGLSMLSTVSTERCLSVLWPIWYRCRRPRHLSAVVCVLLWALSLLLSILEGKFCGFLFSD 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 PSRHLCRTLWLVAAVLLALLCCTMCGASLMLLLRVERGPQRPPPRGFPGLILLTVLLFLF . :.:. ...:. : .: ..::.:: ::.:. : . : . ::::::.::. NP_473 GDSGWCQTFDFITAAWLIFLFMVLCGSSLALLVRILCGSRGLPLTRLYLTILLTVLVFLL 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 CGLPFGIYWLSRNLLWYIPHYFY-HF---SFLMAAVHCAAKPVVYFCLGSAQGR-RL--P ::::::: :. .: .. :. : ...... .:.:..:: .:: . . :: : NP_473 CGLPFGIQWFLILWIWKDSDVLFCHIHPVSVVLSSLNSSANPIIYFFVGSFRKQWRLQQP 240 250 260 270 280 290 290 300 310 pF1KE0 -LRLVLQRALGDEAELGAVRETSRRGLVDIAA :.:.::::: : ::. . :.: ... NP_473 ILKLALQRALQDIAEVDHSEGCFRQGTPEMSRSSLV 300 310 320 330 >>NP_944605 (OMIM: 607231) mas-related G-protein coupled (321 aa) initn: 627 init1: 318 opt: 642 Z-score: 751.5 bits: 147.2 E(85289): 4.1e-35 Smith-Waterman score: 642; 38.6% identity (66.6% similar) in 308 aa overlap (16-312:20-321) 10 20 30 40 50 pF1KE0 MMEPREAGQHVGAANGAQEDVAFNLIILSLTEGLGLGGLLGNGAVLWLLSSNVYRN :. .:. :.. ::. : :. ::. :.:::. ..:: NP_944 MNQTLNSSGTVESALNYSRGSTVHTAY-LVLSSLAMFTCLCGMAGNSMVIWLLGFRMHRN 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 PFAIYLLDVACADLIFLGCHMVAIVPDLLQGRLDFPGFVQTSLATLRFFCYIVGLSLLAA :: ::.:..: :::.:: :.. . : .. :. . : .: : ::::::.: NP_944 PFCIYILNLAAADLLFL-FSMASTLSLETQPLVNTTDKVHELMKRLMYFAYTVGLSLLTA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 VSVEQCLAALFPAWYSCRRPRHLTTCVCALTWALCLLLHLLLSGACTQFFGEPSRHLCRT .:...::..::: :..:.:::::.. ::.: :.::::.. : :. :..:. . :. NP_944 ISTQRCLSVLFPIWFKCHRPRHLSAWVCGLLWTLCLLMNGLTSSFCSKFLKFNEDRCFRV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 LWLVAAVLLALLCCTMCGASLMLLLRVERGPQ---RPPPRGFPGLILLTVLLFLFCGLPF . ::.....: .: .:: :.. :.:. : : : : : ..: .::.::.:.::. NP_944 DMVQAALIMGVLTPVMTLSSLTLFVWVRRSSQQWRRQPTRLFV-VVLASVLVFLICSLPL 180 190 200 210 220 230 240 250 260 270 280 pF1KE0 GIYWLSRNLLWY-IPHYF----YHFSFLMAAVHCAAKPVVYFCLGSAQGRRLPLR---LV .:::. : : .: . . .: : ..: .:.::.:: .:: ...::: : : NP_944 SIYWFV--LYWLSLPPEMQVLCFSLSRLSSSVSSSANPVIYFLVGSRRSHRLPTRSLGTV 240 250 260 270 280 290 290 300 310 pF1KE0 LQRALGDEAELGAVRETSRRGLVDIAA ::.:: .: :: . :: : ...: NP_944 LQQALREEPELEG-GETPTVGTNEMGA 300 310 320 >>NP_473373 (OMIM: 607230) mas-related G-protein coupled (322 aa) initn: 571 init1: 408 opt: 634 Z-score: 742.1 bits: 145.5 E(85289): 1.3e-34 Smith-Waterman score: 634; 37.9% identity (65.8% similar) in 298 aa overlap (8-296:9-301) 10 20 30 40 50 pF1KE0 MMEPREAGQHVGAANGAQEDVAFN--LIILSLTEGLGLGGLLGNGAVLWLLSSNVYRNP : .. :: .: .: : . :: ..: :: ::..:::::. . :: NP_473 MDPTVPVFGTKLTPINGREETPCYNQTLSFTVLTCIISLVGLTGNAVVLWLLGYRMRRNA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 FAIYLLDVACADLIFLGCHMVAIVPDLLQGRLDFPGFVQTSLATLRFFCYIVGLSLLAAV .::.:..: ::..::. ... . : : ... ... :... : :..:::.:.:. NP_473 VSIYILNLAAADFLFLSFQIIRL-PLRL---INISHLIRKILVSVMTFPYFTGLSMLSAI 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 SVEQCLAALFPAWYSCRRPRHLTTCVCALTWALCLLLHLLLSGACTQFFGEPSRHLCRTL :.:.::..:.: :: :::: ::.. ::.: :.: ::. .: : .:. . :.: NP_473 STERCLSVLWPIWYRCRRPTHLSAVVCVLLWGLSLLFSMLEWRFCDFLFSGADSSWCETS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 WLVAAVLLALLCCTMCGASLMLLLRVERGPQRPPPRGFPGLILLTVLLFLFCGLPFGI-- .. .. : .:: ..: .::.::.:. : .. : . ::::::.::.::::::: NP_473 DFIPVAWLIFLCVVLCVSSLVLLVRILCGSRKMPLTRLYVTILLTVLVFLLCGLPFGILG 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 ---YWLSRNLLWYIPHYFYHFSFLMAAVHCAAKPVVYFCLGSAQGR--RLPLRLVLQRAL : . :: : : . ..... .:.:..:: .:: . : : :.::::::: NP_473 ALIYRMHLNLEVLYCHV-YLVCMSLSSLNSSANPIIYFFVGSFRQRQNRQNLKLVLQRAL 240 250 260 270 280 290 300 310 pF1KE0 GDEAELGAVRETSRRGLVDIAA :. :. NP_473 QDKPEVDKGEGQLPEESLELSGSRLGP 300 310 320 >>NP_001157849 (OMIM: 607234) mas-related G-protein coup (289 aa) initn: 597 init1: 228 opt: 595 Z-score: 697.3 bits: 137.1 E(85289): 4.2e-32 Smith-Waterman score: 595; 38.8% identity (63.6% similar) in 286 aa overlap (23-308:11-289) 10 20 30 40 50 60 pF1KE0 MMEPREAGQHVGAANGAQEDVAFNLIILSLTEGLGLGGLLGNGAVLWLLSSNVYRNPFAI :. ... :: .:::: .::: ::: :. . ..::.: NP_001 MFGLFGLWRTFDSVVFYLTLIVGLGGPVGNGLVLWNLGFRIKKGPFSI 10 20 30 40 70 80 90 100 110 120 pF1KE0 YLLDVACADLIFLGCHMVAIVPDLLQGRLDFPGFVQTSLATLRFFCYIVGLSLLAAVSVE ::: .: ::..::.:.. : . : : :: : :. . ::: :::: ::: NP_001 YLLHLAAADFLFLSCRVGFSVAQAALGAQDTLYFV------LTFLWFAVGLWLLAAFSVE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 QCLAALFPAWYSCRRPRHLTTCVCALTWALCLLLHLLLSGACTQFFGEPSRHLCRTLWLV .::. :::: :. :::: .. .:::.:. : : ..:: . . .: .. NP_001 RCLSDLFPACYQGCRPRHASAVLCALVWTPTLPAVPLPANACGLLRNSACPLVCPRYHVA 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE0 AAVLLALLCCTMCGASLMLLLRVERGPQRPPPRGFPGLILLTVLLFLFCGLPFGIYWLSR ... . .: . :...:.. : :: :: . :..: ..::..::::: .:: . NP_001 SVTWFLVLARVAWTAGVVLFVWVTCCSTRPRPRLY-GIVLGALLLLFFCGLPSVFYWSLQ 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE0 NLLWYIPHYFYHFSFLMAAVHCAAKPVVYFCLGSAQGRRLPLRLVLQRALGDEAELGAVR :: .. : .. :.: :. ..::..: :: :.: ::: ::.::::. ::::: NP_001 PLLNFLLPVFSPLATLLACVNSSSKPLIYSGLGRQPGKREPLRSVLRRALGEGAELGARG 230 240 250 260 270 280 310 pF1KE0 ETSRRGLVDIAA .. ::. NP_001 QSLPMGLL >>XP_016872659 (OMIM: 607233) PREDICTED: mas-related G-p (343 aa) initn: 515 init1: 368 opt: 551 Z-score: 645.1 bits: 127.7 E(85289): 3.4e-29 Smith-Waterman score: 551; 39.6% identity (64.5% similar) in 273 aa overlap (34-297:54-321) 10 20 30 40 50 60 pF1KE0 PREAGQHVGAANGAQEDVAFNLIILSLTEGLGLGGLLGNGAVLWLLSSNVYRNPFAIYLL : : ::.::: :::... .. ::::.::.: XP_016 APELYSRGFLTIEQIAMLPPPAVMNYIFLLLCLCGLVGNGLVLWFFGFSIKRNPFSIYFL 30 40 50 60 70 80 70 80 90 100 110 120 pF1KE0 DVACADLIFLGCHMVAIVPDLLQGRLD-FPGFVQTSLATLRFFCYIVGLSLLAAVSVEQC .: ::. .: . : . . : : : .... .: . ...:.::: :::.:.: XP_016 HLASADVGYLFSKAVFSILNT-GGFLGTFADYIRSVCRVLGLCMFLTGVSLLPAVSAERC 90 100 110 120 130 140 130 140 150 160 170 180 pF1KE0 LAALFPAWYSCRRPRHLTTCVCALTWALCLLLHLLLSGACTQFFGEPSRHL-CRTLWLVA ...::::: :::..:.. :::: :.: ::. : . :. :.:. . :: . . XP_016 ASVIFPAWYWRRRPKRLSAVVCALLWVLSLLVTCLHNYFCV-FLGRGAPGAACRHMDIFL 150 160 170 180 190 200 190 200 210 220 230 pF1KE0 AVLLALLCCT-MCGASLMLLLRVE-RGPQRPPPRGFPGLILLTVLLFLFCGLPFGIYWLS ..:: :::: : : :.:.:: :. .: . .:: : .:: .. .:: :. XP_016 GILLFLLCCPLMVLPCLALILHVECRARRRQRSAKLNHVILAMVSVFLVSSIYLGIDWF- 210 220 230 240 250 260 240 250 260 270 280 290 pF1KE0 RNLLWY--IPHYFYHF-SFLMAAVHCAAKPVVYFCLGSAQGRRL--PLRLVLQRALGDEA :.: :: : .. . : .. .:::.::: : ...:: :::.:.:::: : : XP_016 --LFWVFQIPAPFPEYVTDLCICINSSAKPIVYFLAGRDKSQRLWEPLRVVFQRALRDGA 270 280 290 300 310 300 310 pF1KE0 ELGAVRETSRRGLVDIAA ::: XP_016 ELGEAGGSTPNTVTMEMQCPPGNAS 320 330 340 312 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 03:13:38 2016 done: Sat Nov 5 03:13:39 2016 Total Scan time: 7.770 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]