FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0804, 289 aa 1>>>pF1KE0804 289 - 289 aa - 289 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.6336+/-0.000336; mu= 20.0438+/- 0.021 mean_var=85.1252+/-19.048, 0's: 0 Z-trim(116.3): 152 B-trim: 1699 in 2/51 Lambda= 0.139010 statistics sampled from 27141 (27318) to 27141 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.32), width: 16 Scan time: 7.360 The best scores are: opt bits E(85289) NP_001157849 (OMIM: 607234) mas-related G-protein ( 289) 1995 409.6 3.5e-114 NP_001034254 (OMIM: 607232) mas-related G-protein ( 312) 595 128.9 1.2e-29 NP_671732 (OMIM: 607227) mas-related G-protein cou ( 322) 546 119.1 1.1e-26 XP_011518184 (OMIM: 607229) PREDICTED: mas-related ( 322) 505 110.9 3.3e-24 NP_473372 (OMIM: 607229) mas-related G-protein cou ( 322) 505 110.9 3.3e-24 NP_473373 (OMIM: 607230) mas-related G-protein cou ( 322) 500 109.9 6.7e-24 NP_473371 (OMIM: 607228) mas-related G-protein cou ( 330) 483 106.5 7.2e-23 NP_001290544 (OMIM: 607228) mas-related G-protein ( 330) 483 106.5 7.2e-23 NP_944605 (OMIM: 607231) mas-related G-protein cou ( 321) 459 101.6 2e-21 NP_002368 (OMIM: 165180) proto-oncogene Mas [Homo ( 325) 369 83.6 5.5e-16 NP_443199 (OMIM: 607235) mas-related G-protein cou ( 378) 367 83.3 7.9e-16 XP_016872659 (OMIM: 607233) PREDICTED: mas-related ( 343) 361 82.0 1.7e-15 NP_001091985 (OMIM: 607233) mas-related G-protein ( 343) 361 82.0 1.7e-15 NP_659452 (OMIM: 607233) mas-related G-protein cou ( 343) 361 82.0 1.7e-15 NP_005284 (OMIM: 601908) G-protein coupled recepto ( 358) 189 47.6 4.3e-05 NP_001313404 (OMIM: 605246) C3a anaphylatoxin chem ( 482) 187 47.3 6.8e-05 NP_001313406 (OMIM: 605246) C3a anaphylatoxin chem ( 482) 187 47.3 6.8e-05 NP_004045 (OMIM: 605246) C3a anaphylatoxin chemota ( 482) 187 47.3 6.8e-05 NP_001497 (OMIM: 603195) probable G-protein couple ( 356) 183 46.3 9.8e-05 NP_002020 (OMIM: 136537) fMet-Leu-Phe receptor [Ho ( 350) 177 45.1 0.00022 NP_001180235 (OMIM: 136537) fMet-Leu-Phe receptor ( 350) 177 45.1 0.00022 NP_001243495 (OMIM: 601919) proteinase-activated r ( 352) 172 44.1 0.00045 NP_004092 (OMIM: 601919) proteinase-activated rece ( 374) 172 44.2 0.00047 XP_016874309 (OMIM: 602351) PREDICTED: chemokine-l ( 371) 163 42.4 0.0016 NP_004063 (OMIM: 602351) chemokine-like receptor 1 ( 371) 163 42.4 0.0016 NP_001135817 (OMIM: 602351) chemokine-like recepto ( 373) 163 42.4 0.0016 NP_001135816 (OMIM: 602351) chemokine-like recepto ( 373) 163 42.4 0.0016 NP_001135815 (OMIM: 602351) chemokine-like recepto ( 373) 163 42.4 0.0016 XP_011524989 (OMIM: 136539) PREDICTED: N-formyl pe ( 353) 162 42.1 0.0018 NP_002021 (OMIM: 136539) N-formyl peptide receptor ( 353) 162 42.1 0.0018 NP_001727 (OMIM: 113995) C5a anaphylatoxin chemota ( 350) 159 41.5 0.0027 NP_001005738 (OMIM: 136538) N-formyl peptide recep ( 351) 157 41.1 0.0036 XP_006723183 (OMIM: 136538) PREDICTED: N-formyl pe ( 351) 157 41.1 0.0036 XP_016882031 (OMIM: 136538) PREDICTED: N-formyl pe ( 351) 157 41.1 0.0036 NP_001453 (OMIM: 136538) N-formyl peptide receptor ( 351) 157 41.1 0.0036 NP_005290 (OMIM: 602043) 12-(S)-hydroxy-5,8,10,14- ( 319) 156 40.9 0.0039 XP_016884927 (OMIM: 300086) PREDICTED: lysophospha ( 370) 156 41.0 0.0043 XP_006724702 (OMIM: 300086) PREDICTED: lysophospha ( 370) 156 41.0 0.0043 XP_016884926 (OMIM: 300086) PREDICTED: lysophospha ( 370) 156 41.0 0.0043 XP_005262183 (OMIM: 300086) PREDICTED: lysophospha ( 370) 156 41.0 0.0043 NP_001264929 (OMIM: 300086) lysophosphatidic acid ( 370) 156 41.0 0.0043 NP_005287 (OMIM: 300086) lysophosphatidic acid rec ( 370) 156 41.0 0.0043 XP_005254102 (OMIM: 606922) PREDICTED: 2-oxoglutar ( 337) 155 40.7 0.0046 NP_001333125 (OMIM: 606922) 2-oxoglutarate recepto ( 337) 155 40.7 0.0046 NP_001333123 (OMIM: 606922) 2-oxoglutarate recepto ( 337) 155 40.7 0.0046 XP_005254100 (OMIM: 606922) PREDICTED: 2-oxoglutar ( 337) 155 40.7 0.0046 XP_011519379 (OMIM: 606922) PREDICTED: 2-oxoglutar ( 337) 155 40.7 0.0046 NP_001333126 (OMIM: 606922) 2-oxoglutarate recepto ( 337) 155 40.7 0.0046 XP_005254103 (OMIM: 606922) PREDICTED: 2-oxoglutar ( 337) 155 40.7 0.0046 XP_005254101 (OMIM: 606922) PREDICTED: 2-oxoglutar ( 337) 155 40.7 0.0046 >>NP_001157849 (OMIM: 607234) mas-related G-protein coup (289 aa) initn: 1995 init1: 1995 opt: 1995 Z-score: 2171.0 bits: 409.6 E(85289): 3.5e-114 Smith-Waterman score: 1995; 100.0% identity (100.0% similar) in 289 aa overlap (1-289:1-289) 10 20 30 40 50 60 pF1KE0 MFGLFGLWRTFDSVVFYLTLIVGLGGPVGNGLVLWNLGFRIKKGPFSIYLLHLAAADFLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFGLFGLWRTFDSVVFYLTLIVGLGGPVGNGLVLWNLGFRIKKGPFSIYLLHLAAADFLF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 LSCRVGFSVAQAALGAQDTLYFVLTFLWFAVGLWLLAAFSVERCLSDLFPACYQGCRPRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSCRVGFSVAQAALGAQDTLYFVLTFLWFAVGLWLLAAFSVERCLSDLFPACYQGCRPRH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 ASAVLCALVWTPTLPAVPLPANACGLLRNSACPLVCPRYHVASVTWFLVLARVAWTAGVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASAVLCALVWTPTLPAVPLPANACGLLRNSACPLVCPRYHVASVTWFLVLARVAWTAGVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LFVWVTCCSTRPRPRLYGIVLGALLLLFFCGLPSVFYWSLQPLLNFLLPVFSPLATLLAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFVWVTCCSTRPRPRLYGIVLGALLLLFFCGLPSVFYWSLQPLLNFLLPVFSPLATLLAC 190 200 210 220 230 240 250 260 270 280 pF1KE0 VNSSSKPLIYSGLGRQPGKREPLRSVLRRALGEGAELGARGQSLPMGLL ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNSSSKPLIYSGLGRQPGKREPLRSVLRRALGEGAELGARGQSLPMGLL 250 260 270 280 >>NP_001034254 (OMIM: 607232) mas-related G-protein coup (312 aa) initn: 597 init1: 228 opt: 595 Z-score: 653.2 bits: 128.9 E(85289): 1.2e-29 Smith-Waterman score: 595; 38.8% identity (63.6% similar) in 286 aa overlap (11-289:23-308) 10 20 30 40 pF1KE0 MFGLFGLWRTFDSVVFYLTLIVGLGGPVGNGLVLWNLGFRIKKGPFSI :. ... :: .:::: .::: ::: :. . ..::.: NP_001 MMEPREAGQHVGAANGAQEDVAFNLIILSLTEGLGLGGLLGNGAVLWLLSSNVYRNPFAI 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 YLLHLAAADFLFLSCRVGFSVAQAALGAQDTLYFV------LTFLWFAVGLWLLAAFSVE ::: .: ::..::.:.. : . : : :: : :. . ::: :::: ::: NP_001 YLLDVACADLIFLGCHMVAIVPDLLQGRLDFPGFVQTSLATLRFFCYIVGLSLLAAVSVE 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 RCLSDLFPACYQGCRPRHASAVLCALVWTPTLPAVPLPANACGLLRNSACPLVCPRYHVA .::. :::: :. :::: .. .:::.:. : : ..:: . . .: .. NP_001 QCLAALFPAWYSCRRPRHLTTCVCALTWALCLLLHLLLSGACTQFFGEPSRHLCRTLWLV 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE0 SVTWFLVLARVAWTAGVVLFVWVTCCSTRPRPRLY-GIVLGALLLLFFCGLPSVFYWSLQ ... . .: . :...:.. : :: :: . :..: ..::..::::: .:: . NP_001 AAVLLALLCCTMCGASLMLLLRVERGPQRPPPRGFPGLILLTVLLFLFCGLPFGIYWLSR 190 200 210 220 230 240 230 240 250 260 270 280 pF1KE0 PLLNFLLPVFSPLATLLACVNSSSKPLIYSGLGRQPGKREPLRSVLRRALGEGAELGARG :: .. : .. :.: :. ..::..: :: :.: ::: ::.::::. ::::: NP_001 NLLWYIPHYFYHFSFLMAAVHCAAKPVVYFCLGSAQGRRLPLRLVLQRALGDEAELGAVR 250 260 270 280 290 300 pF1KE0 QSLPMGLL .. ::. NP_001 ETSRRGLVDIAA 310 >>NP_671732 (OMIM: 607227) mas-related G-protein coupled (322 aa) initn: 543 init1: 214 opt: 546 Z-score: 599.9 bits: 119.1 E(85289): 1.1e-26 Smith-Waterman score: 546; 38.5% identity (64.0% similar) in 283 aa overlap (18-289:33-313) 10 20 30 40 pF1KE0 MFGLFGLWRTFDSVVFYLTLIVGLGGPVGNGLVLWNLGFRIKKGPFS :: ::.: : .::..::: :: :.... :: NP_671 PTISTLDTELTPINGTEETLCYKQTLSLTVLTCIVSLVGLTGNAVVLWLLGCRMRRNAFS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 IYLLHLAAADFLFLSCRVGFSV---AQAALGAQDTLYFVLTFLWFAVGLWLLAAFSVERC ::.:.:::::::::: :. .:. . . :: :. : .:: :: .:.: :.::: NP_671 IYILNLAAADFLFLSGRLIYSLLSFISIPHTISKILYPVMMFSYFA-GLSFLSAVSTERC 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 LSDLFPACYQGCRPRHASAVLCALVWTPTLPAVPLPANACGLLRNSACPLVCPRYHVASV :: :.: :. :: : :::.:.:.:. .: : ::.: ..: : .: NP_671 LSVLWPIWYRCHRPTHLSAVVCVLLWALSLLRSILEWMLCGFLFSGADSAWCQTSDFITV 130 140 150 160 170 180 170 180 190 200 210 pF1KE0 TWFLVLARVAWTAGVVLFVWVTCCSTR-PRPRLYGIVLGALLLLFFCGLPS-----VFYW .:.. : : ...::.. . : : . : ::: .: ..:....:::: .: : NP_671 AWLIFLCVVLCGSSLVLLIRILCGSRKIPLTRLYVTILLTVLVFLLCGLPFGIQFFLFLW 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE0 SLQPLLNFLLPVFSPLATLLACVNSSSKPLIYSGLG--RQPGKREPLRSVLRRALGEGAE .. . :. .. .:. .:::..:.:: .: :: .:. :. ::.::: ...: NP_671 -IHVDREVLFCHVHLVSIFLSALNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQDASE 250 260 270 280 290 300 280 pF1KE0 LGARGQSLPMGLL . : .:: .: NP_671 VDEGGGQLPEEILELSGSRLEQ 310 320 >>XP_011518184 (OMIM: 607229) PREDICTED: mas-related G-p (322 aa) initn: 498 init1: 208 opt: 505 Z-score: 555.5 bits: 110.9 E(85289): 3.3e-24 Smith-Waterman score: 505; 36.2% identity (63.5% similar) in 282 aa overlap (18-289:33-313) 10 20 30 40 pF1KE0 MFGLFGLWRTFDSVVFYLTLIVGLGGPVGNGLVLWNLGFRIKKGPFS :: ::.: . .::..::: :: :.... : XP_011 STIPVLGTELTPINGREETPCYKQTLSFTGLTCIVSLVALTGNAVVLWLLGCRMRRNAVS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 IYLLHLAAADFLFLSCRVGFS---VAQAALGAQDTLYFVLTFLWFAVGLWLLAAFSVERC ::.:.:.:::::::: .. : . . . : :.:: .: .:: .:.:.:.::: XP_011 IYILNLVAADFLFLSGHIICSPLRLINIRHPISKILSPVMTFPYF-IGLSMLSAISTERC 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 LSDLFPACYQGCRPRHASAVLCALVWTPTLPAVPLPANACGLLRNSACPLVCPRYHVASV :: :.: :. :::. :.:.:.:.:. .: : : .: ..: . : .. XP_011 LSILWPIWYHCRRPRYLSSVMCVLLWALSLLRSILEWMFCDFLFSGANSVWCETSDFITI 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE0 TWFLVLARVAWTAGVVLFVWVTCCSTR-PRPRLYGIVLGALLLLFFCGLPSVFYWSLQPL .:.. : : ...::.: . : : . : ::: .: ..:....:::: . :.: XP_011 AWLVFLCVVLCGSSLVLLVRILCGSRKMPLTRLYVTILLTVLVFLLCGLPFGIQWALFSR 190 200 210 220 230 240 230 240 250 260 270 pF1KE0 LNFLLPVF----SPLATLLACVNSSSKPLIYSGLG--RQPGKREPLRSVLRRALGEGAEL ... :. .. .:. .:::..:.:: .: :: .:. :. ::.::: . :. XP_011 IHLDWKVLFCHVHLVSIFLSALNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQDTPEV 250 260 270 280 290 300 280 pF1KE0 GARGQSLPMGLL : ::. : XP_011 DEGGGWLPQETLELSGSRLEQ 310 320 >>NP_473372 (OMIM: 607229) mas-related G-protein coupled (322 aa) initn: 498 init1: 208 opt: 505 Z-score: 555.5 bits: 110.9 E(85289): 3.3e-24 Smith-Waterman score: 505; 36.2% identity (63.5% similar) in 282 aa overlap (18-289:33-313) 10 20 30 40 pF1KE0 MFGLFGLWRTFDSVVFYLTLIVGLGGPVGNGLVLWNLGFRIKKGPFS :: ::.: . .::..::: :: :.... : NP_473 STIPVLGTELTPINGREETPCYKQTLSFTGLTCIVSLVALTGNAVVLWLLGCRMRRNAVS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 IYLLHLAAADFLFLSCRVGFS---VAQAALGAQDTLYFVLTFLWFAVGLWLLAAFSVERC ::.:.:.:::::::: .. : . . . : :.:: .: .:: .:.:.:.::: NP_473 IYILNLVAADFLFLSGHIICSPLRLINIRHPISKILSPVMTFPYF-IGLSMLSAISTERC 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 LSDLFPACYQGCRPRHASAVLCALVWTPTLPAVPLPANACGLLRNSACPLVCPRYHVASV :: :.: :. :::. :.:.:.:.:. .: : : .: ..: . : .. NP_473 LSILWPIWYHCRRPRYLSSVMCVLLWALSLLRSILEWMFCDFLFSGANSVWCETSDFITI 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE0 TWFLVLARVAWTAGVVLFVWVTCCSTR-PRPRLYGIVLGALLLLFFCGLPSVFYWSLQPL .:.. : : ...::.: . : : . : ::: .: ..:....:::: . :.: NP_473 AWLVFLCVVLCGSSLVLLVRILCGSRKMPLTRLYVTILLTVLVFLLCGLPFGIQWALFSR 190 200 210 220 230 240 230 240 250 260 270 pF1KE0 LNFLLPVF----SPLATLLACVNSSSKPLIYSGLG--RQPGKREPLRSVLRRALGEGAEL ... :. .. .:. .:::..:.:: .: :: .:. :. ::.::: . :. NP_473 IHLDWKVLFCHVHLVSIFLSALNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQDTPEV 250 260 270 280 290 300 280 pF1KE0 GARGQSLPMGLL : ::. : NP_473 DEGGGWLPQETLELSGSRLEQ 310 320 >>NP_473373 (OMIM: 607230) mas-related G-protein coupled (322 aa) initn: 504 init1: 204 opt: 500 Z-score: 550.1 bits: 109.9 E(85289): 6.7e-24 Smith-Waterman score: 500; 37.4% identity (62.9% similar) in 278 aa overlap (18-285:33-309) 10 20 30 40 pF1KE0 MFGLFGLWRTFDSVVFYLTLIVGLGGPVGNGLVLWNLGFRIKKGPFS :: :..: : .::..::: ::.:.... : NP_473 PTVPVFGTKLTPINGREETPCYNQTLSFTVLTCIISLVGLTGNAVVLWLLGYRMRRNAVS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 IYLLHLAAADFLFLSC---RVGFSVAQAALGAQDTLYFVLTFLWFAVGLWLLAAFSVERC ::.:.:::::::::: :. . . . . . : :.:: .:. :: .:.:.:.::: NP_473 IYILNLAAADFLFLSFQIIRLPLRLINISHLIRKILVSVMTFPYFT-GLSMLSAISTERC 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 LSDLFPACYQGCRPRHASAVLCALVWTPTLPAVPLPANACGLLRNSACPLVCPRYHVASV :: :.: :. :: : :::.:.:.: .: : : .: ..: : : NP_473 LSVLWPIWYRCRRPTHLSAVVCVLLWGLSLLFSMLEWRFCDFLFSGADSSWCETSDFIPV 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE0 TWFLVLARVAWTAGVVLFVWVTCCSTR-PRPRLYGIVLGALLLLFFCGLPSVFYWSLQPL .:.. : : ....::.: . : : . : ::: .: ..:....:::: . .: NP_473 AWLIFLCVVLCVSSLVLLVRILCGSRKMPLTRLYVTILLTVLVFLLCGLPFGILGALIYR 190 200 210 220 230 240 230 240 250 260 270 pF1KE0 LNFLLPVFSPLATL----LACVNSSSKPLIYSGLG--RQPGKREPLRSVLRRALGEGAEL ... : :. . : :. .:::..:.:: .: :: .:. :. ::.::: . :. NP_473 MHLNLEVLYCHVYLVCMSLSSLNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQDKPEV 250 260 270 280 290 300 280 pF1KE0 GARGQSLPMGLL .:: NP_473 DKGEGQLPEESLELSGSRLGP 310 320 >>NP_473371 (OMIM: 607228) mas-related G-protein coupled (330 aa) initn: 504 init1: 211 opt: 483 Z-score: 531.5 bits: 106.5 E(85289): 7.2e-23 Smith-Waterman score: 502; 36.1% identity (65.3% similar) in 277 aa overlap (17-277:35-310) 10 20 30 40 pF1KE0 MFGLFGLWRTFDSVVFYLTLIVGLGGPVGNGLVLWNLGFRIKKGPF .: :...: : ::::.::: ::::.... : NP_473 TPAWGTESTTVNGNDQALLLLCGKETLIPVFLILFIALVGLVGNGFVLWLLGFRMRRNAF 10 20 30 40 50 60 50 60 70 80 90 pF1KE0 SIYLLHLAAADFLFL-----SCRVGFSVAQAALGAQDTLYF--VLTFLWFAVGLWLLAAF :.:.: ::.:::::: .: : .: ... . .: :.: ..: :: .:.. NP_473 SVYVLSLAGADFLFLCFQIINCLVYLSNFFCSISINFPSFFTTVMTCAYLA-GLSMLSTV 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 SVERCLSDLFPACYQGCRPRHASAVLCALVWTPTLPAVPLPANACGLLRNSACPLVCPRY :.::::: :.: :. :::: :::.:.:.:. .: : .. ::.: ... : . NP_473 STERCLSVLWPIWYRCRRPRHLSAVVCVLLWALSLLLSILEGKFCGFLFSDGDSGWCQTF 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE0 HVASVTWFLVLARVAWTAGVVLFVWVTCCSTR-PRPRLYGIVLGALLLLFFCGLPSVFYW ...:.. : : ....:.: . : : : ::: .: ..:....:::: . : NP_473 DFITAAWLIFLFMVLCGSSLALLVRILCGSRGLPLTRLYLTILLTVLVFLLCGLPFGIQW 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE0 SLQPLL----NFLLPVFSPLATLLACVNSSSKPLIYSGLG---RQPGKREP-LRSVLRRA : . . :. . :....:. .:::..:.:: .: .: ..: :. .:.:: NP_473 FLILWIWKDSDVLFCHIHPVSVVLSSLNSSANPIIYFFVGSFRKQWRLQQPILKLALQRA 250 260 270 280 290 300 280 pF1KE0 LGEGAELGARGQSLPMGLL : . ::. NP_473 LQDIAEVDHSEGCFRQGTPEMSRSSLV 310 320 330 >>NP_001290544 (OMIM: 607228) mas-related G-protein coup (330 aa) initn: 504 init1: 211 opt: 483 Z-score: 531.5 bits: 106.5 E(85289): 7.2e-23 Smith-Waterman score: 502; 36.1% identity (65.3% similar) in 277 aa overlap (17-277:35-310) 10 20 30 40 pF1KE0 MFGLFGLWRTFDSVVFYLTLIVGLGGPVGNGLVLWNLGFRIKKGPF .: :...: : ::::.::: ::::.... : NP_001 TPAWGTESTTVNGNDQALLLLCGKETLIPVFLILFIALVGLVGNGFVLWLLGFRMRRNAF 10 20 30 40 50 60 50 60 70 80 90 pF1KE0 SIYLLHLAAADFLFL-----SCRVGFSVAQAALGAQDTLYF--VLTFLWFAVGLWLLAAF :.:.: ::.:::::: .: : .: ... . .: :.: ..: :: .:.. NP_001 SVYVLSLAGADFLFLCFQIINCLVYLSNFFCSISINFPSFFTTVMTCAYLA-GLSMLSTV 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 SVERCLSDLFPACYQGCRPRHASAVLCALVWTPTLPAVPLPANACGLLRNSACPLVCPRY :.::::: :.: :. :::: :::.:.:.:. .: : .. ::.: ... : . NP_001 STERCLSVLWPIWYRCRRPRHLSAVVCVLLWALSLLLSILEGKFCGFLFSDGDSGWCQTF 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE0 HVASVTWFLVLARVAWTAGVVLFVWVTCCSTR-PRPRLYGIVLGALLLLFFCGLPSVFYW ...:.. : : ....:.: . : : : ::: .: ..:....:::: . : NP_001 DFITAAWLIFLFMVLCGSSLALLVRILCGSRGLPLTRLYLTILLTVLVFLLCGLPFGIQW 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE0 SLQPLL----NFLLPVFSPLATLLACVNSSSKPLIYSGLG---RQPGKREP-LRSVLRRA : . . :. . :....:. .:::..:.:: .: .: ..: :. .:.:: NP_001 FLILWIWKDSDVLFCHIHPVSVVLSSLNSSANPIIYFFVGSFRKQWRLQQPILKLALQRA 250 260 270 280 290 300 280 pF1KE0 LGEGAELGARGQSLPMGLL : . ::. NP_001 LQDIAEVDHSEGCFRQGTPEMSRSSLV 310 320 330 >>NP_944605 (OMIM: 607231) mas-related G-protein coupled (321 aa) initn: 411 init1: 191 opt: 459 Z-score: 505.7 bits: 101.6 E(85289): 2e-21 Smith-Waterman score: 486; 37.5% identity (66.9% similar) in 293 aa overlap (14-287:29-315) 10 20 30 40 pF1KE0 MFGLFGLWRTFDSVVFYLTLIVGLGGPVGNGLVLWNLGFRIKKGP :. :.... : : .::..:.: ::::....: NP_944 MNQTLNSSGTVESALNYSRGSTVHTAYLVLSSLAMFTCLCGMAGNSMVIWLLGFRMHRNP 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 FSIYLLHLAAADFLFL-SCRVGFSV-AQAALGAQDTLYFVLT-FLWFA--VGLWLLAAFS : ::.:.:::::.::: : .:. .: ... : .. .. ...:: ::: ::.:.: NP_944 FCIYILNLAAADLLFLFSMASTLSLETQPLVNTTDKVHELMKRLMYFAYTVGLSLLTAIS 70 80 90 100 110 120 110 120 130 140 150 pF1KE0 VERCLSDLFPACYQGCRPRHASAVLCALVWTPTLPAVPLPANACG-LLRNSACPLVCPRY ..:::: ::: .. :::: :: .:.:.:: : : .. :. .:. . : : NP_944 TQRCLSVLFPIWFKCHRPRHLSAWVCGLLWTLCLLMNGLTSSFCSKFLKFNED--RCFRV 130 140 150 160 170 160 170 180 190 200 210 pF1KE0 HVASVTWFL-VLARVAWTAGVVLFVWVTCCST--RPRP-RLYGIVLGALLLLFFCGLPSV ..... .. ::. : ....::::: : : .: ::. .::...:....:.:: NP_944 DMVQAALIMGVLTPVMTLSSLTLFVWVRRSSQQWRRQPTRLFVVVLASVLVFLICSLPLS 180 190 200 210 220 230 220 230 240 250 260 pF1KE0 FYW------SLQPLLNFLLPVFSPLATLLACVNSSSKPLIYSGLGRQPGKREPLRS---V .:: :: : .. : :: :. : . :.::..:.:: .: . ..: : :: : NP_944 IYWFVLYWLSLPPEMQVL--CFS-LSRLSSSVSSSANPVIYFLVGSRRSHRLPTRSLGTV 240 250 260 270 280 290 270 280 pF1KE0 LRRALGEGAELGARGQSLPMGLL :..:: : :: . :.. .: NP_944 LQQALREEPELEG-GETPTVGTNEMGA 300 310 320 >>NP_002368 (OMIM: 165180) proto-oncogene Mas [Homo sapi (325 aa) initn: 330 init1: 160 opt: 369 Z-score: 408.0 bits: 83.6 E(85289): 5.5e-16 Smith-Waterman score: 369; 29.1% identity (59.6% similar) in 285 aa overlap (14-282:34-312) 10 20 30 40 pF1KE0 MFGLFGLWRTFDSVVFYLTLIVGLGGPVGNGLVLWNLGFRIKK .: .. . .. : : ::..:: : ::... NP_002 SNVTSFVVEEPTNISTGRNASVGNAHRQIPIVHWVIMSISPVGFVENGILLWFLCFRMRR 10 20 30 40 50 60 50 60 70 80 90 pF1KE0 GPFSIYLLHLAAADFLFLSCRVGFSVAQA-----ALGAQDTLYFV-LTFLW-FAVGLWLL .::..:. ::. ::. .: : .:. : . : :. . .:::. . .::.:: NP_002 NPFTVYITHLSIADISLLFCIFILSIDYALDYELSSGHYYTIVTLSVTFLFGYNTGLYLL 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 AAFSVERCLSDLFPACYQGCRPRHASAVLCALVWTPTLPAVPLPANAC------GLLRNS .:.::::::: :.: :. ::.. ::..:::.:. . .. . : . ::. NP_002 TAISVERCLSVLYPIWYRCHRPKYQSALVCALLWALSCLVTTMEYVMCIDREEESHSRND 130 140 150 160 170 180 160 170 180 190 200 pF1KE0 ACPLVCPRYHVASVTWFLVLARVAWTAGVVLFVWVTCCS-TRPRPRLYGIVLGALLLLFF : : . : :::.. . .....: : . . . .:: ... ....... NP_002 -CRAVIIFIAILS---FLVFTPLMLVSSTILVVKIRKNTWASHSSKLYIVIMVTIIIFLI 190 200 210 220 230 210 220 230 240 250 260 pF1KE0 CGLPSVFYWSLQPLLNFLLPVFSPLATLLACVNSSSKPLIYSGLGRQPGKR--EPLRSVL ..: . . : . . .. :.. .:::..:.:: .: . :: : :. :: NP_002 FAMPMRLLYLLYYEYWSTFGNLHHISLLFSTINSSANPFIYFFVGSSKKKRFKESLKVVL 240 250 260 270 280 290 270 280 pF1KE0 RRALGEGAELGARGQSLPMGLL ::. . :. : : NP_002 TRAFKD--EMQPRRQKDNCNTVTVETVV 300 310 320 289 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 03:14:11 2016 done: Sat Nov 5 03:14:12 2016 Total Scan time: 7.360 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]