Result of FASTA (omim) for
pF1KE0841
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0841, 342 aa
1>>>pF1KE0841 342 - 342 aa - 342 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6109+/-0.0005; mu= 20.3629+/- 0.031
mean_var=102.4452+/-26.908, 0's: 0 Z-trim(109.3): 541 B-trim: 2039 in 2/48
Lambda= 0.126715
statistics sampled from 16714 (17480) to 16714 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.54), E-opt: 0.2 (0.205), width: 16
Scan time: 7.500
The best scores are: opt bits E(85289)
NP_444508 (OMIM: 606927) trace amine-associated re ( 342) 2255 423.6 3.1e-118
NP_778237 (OMIM: 608923) trace amine-associated re ( 345) 1880 355.0 1.4e-97
NP_778227 (OMIM: 608282) trace amine-associated re ( 348) 1625 308.4 1.5e-83
NP_003958 (OMIM: 607405) trace amine-associated re ( 337) 1019 197.6 3.3e-50
NP_612200 (OMIM: 609333) trace amine-associated re ( 339) 920 179.5 9.2e-45
NP_001028252 (OMIM: 604849) trace amine-associated ( 351) 851 166.9 5.9e-41
NP_055441 (OMIM: 604849) trace amine-associated re ( 306) 800 157.5 3.5e-38
XP_016868585 (OMIM: 104221) PREDICTED: alpha-1A ad ( 317) 407 85.7 1.5e-16
NP_001035262 (OMIM: 602164) 5-hydroxytryptamine re ( 360) 405 85.4 2.1e-16
NP_955525 (OMIM: 602164) 5-hydroxytryptamine recep ( 378) 405 85.4 2.1e-16
NP_001035259 (OMIM: 602164) 5-hydroxytryptamine re ( 387) 405 85.4 2.2e-16
NP_000861 (OMIM: 602164) 5-hydroxytryptamine recep ( 388) 405 85.4 2.2e-16
XP_011542713 (OMIM: 104221) PREDICTED: alpha-1A ad ( 324) 404 85.1 2.2e-16
NP_001273339 (OMIM: 602164) 5-hydroxytryptamine re ( 411) 405 85.5 2.2e-16
NP_001035263 (OMIM: 602164) 5-hydroxytryptamine re ( 428) 405 85.5 2.3e-16
XP_011542714 (OMIM: 104221) PREDICTED: alpha-1A ad ( 308) 403 84.9 2.4e-16
NP_001309433 (OMIM: 104221) alpha-1A adrenergic re ( 342) 403 85.0 2.6e-16
NP_001309432 (OMIM: 104221) alpha-1A adrenergic re ( 370) 403 85.0 2.7e-16
NP_001309431 (OMIM: 104221) alpha-1A adrenergic re ( 372) 403 85.0 2.7e-16
XP_006716356 (OMIM: 104221) PREDICTED: alpha-1A ad ( 429) 403 85.1 3e-16
NP_150645 (OMIM: 104221) alpha-1A adrenergic recep ( 429) 403 85.1 3e-16
NP_150647 (OMIM: 104221) alpha-1A adrenergic recep ( 455) 403 85.2 3.1e-16
NP_000671 (OMIM: 104221) alpha-1A adrenergic recep ( 466) 403 85.2 3.1e-16
XP_006716355 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475) 403 85.2 3.2e-16
NP_150646 (OMIM: 104221) alpha-1A adrenergic recep ( 475) 403 85.2 3.2e-16
XP_016868584 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475) 403 85.2 3.2e-16
XP_016868583 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475) 403 85.2 3.2e-16
NP_071640 (OMIM: 142703) histamine H2 receptor iso ( 359) 383 81.4 3.4e-15
XP_006714928 (OMIM: 142703) PREDICTED: histamine H ( 362) 383 81.4 3.4e-15
NP_001124527 (OMIM: 142703) histamine H2 receptor ( 397) 383 81.4 3.6e-15
XP_005265961 (OMIM: 142703) PREDICTED: histamine H ( 422) 383 81.5 3.7e-15
XP_016864915 (OMIM: 142703) PREDICTED: histamine H ( 422) 383 81.5 3.7e-15
XP_011532851 (OMIM: 142703) PREDICTED: histamine H ( 422) 383 81.5 3.7e-15
XP_006714927 (OMIM: 142703) PREDICTED: histamine H ( 422) 383 81.5 3.7e-15
XP_011532850 (OMIM: 142703) PREDICTED: histamine H ( 422) 383 81.5 3.7e-15
NP_057624 (OMIM: 605569) probable G-protein couple ( 423) 377 80.4 7.9e-15
NP_000854 (OMIM: 182131) 5-hydroxytryptamine recep ( 390) 375 79.9 9.8e-15
NP_000672 (OMIM: 104210) alpha-2A adrenergic recep ( 465) 375 80.1 1.1e-14
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 374 79.9 1.2e-14
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin ( 528) 374 79.9 1.3e-14
NP_000855 (OMIM: 182133) 5-hydroxytryptamine recep ( 377) 370 79.0 1.8e-14
NP_001265427 (OMIM: 102776) adenosine receptor A2a ( 412) 369 78.9 2.2e-14
NP_000666 (OMIM: 102776) adenosine receptor A2a [H ( 412) 369 78.9 2.2e-14
NP_001265426 (OMIM: 102776) adenosine receptor A2a ( 412) 369 78.9 2.2e-14
NP_001265428 (OMIM: 102776) adenosine receptor A2a ( 412) 369 78.9 2.2e-14
NP_001265429 (OMIM: 102776) adenosine receptor A2a ( 412) 369 78.9 2.2e-14
NP_000015 (OMIM: 109690,600807,601665) beta-2 adre ( 413) 369 78.9 2.2e-14
NP_000673 (OMIM: 104260,607876) alpha-2B adrenergi ( 450) 367 78.6 2.9e-14
XP_005264808 (OMIM: 182134) PREDICTED: 5-hydroxytr ( 366) 362 77.5 4.9e-14
NP_001309138 (OMIM: 182134) 5-hydroxytryptamine re ( 366) 362 77.5 4.9e-14
>>NP_444508 (OMIM: 606927) trace amine-associated recept (342 aa)
initn: 2255 init1: 2255 opt: 2255 Z-score: 2243.6 bits: 423.6 E(85289): 3.1e-118
Smith-Waterman score: 2255; 100.0% identity (100.0% similar) in 342 aa overlap (1-342:1-342)
10 20 30 40 50 60
pF1KE0 MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 QLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 QLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 HLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 HLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 SALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 SALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 SESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 SESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAY
250 260 270 280 290 300
310 320 330 340
pF1KE0 YNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE
::::::::::::::::::::::::::::::::::::::::::
NP_444 YNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE
310 320 330 340
>>NP_778237 (OMIM: 608923) trace amine-associated recept (345 aa)
initn: 1890 init1: 1870 opt: 1880 Z-score: 1873.0 bits: 355.0 E(85289): 1.4e-97
Smith-Waterman score: 1880; 79.6% identity (92.7% similar) in 343 aa overlap (1-342:1-343)
10 20 30 40 50
pF1KE0 MTSNFSQPV-VQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHF
:.:: : : ::::: .:::::.. :.::::::::: .:.::..:::::::::: :.:::
NP_778 MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 KQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSV
::::::::::.::::::::::::::: :::::::::::::: .:::.:.::::::::::.
NP_778 KQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 LHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEEL
.::::: :::::.::::::: :::::::::::::::::::: :::::::::: :::::::
NP_778 FHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEEL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 VSALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVES
.::::.:::: .:.:.::: ::: :::::..:::::..:::.:..:: :::.:.::.::
NP_778 SDALNCIGGCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTES
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE0 SSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSA
:::::: :::.:::::::::::::.::.::::::..: ::::::::.::: ::::::: :
NP_778 SSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCA
250 260 270 280 290 300
300 310 320 330 340
pF1KE0 YYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE
:::::::::::::::::::::::.:..:.::: ::.:..:: :
NP_778 YYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI
310 320 330 340
>>NP_778227 (OMIM: 608282) trace amine-associated recept (348 aa)
initn: 1657 init1: 1596 opt: 1625 Z-score: 1621.1 bits: 308.4 E(85289): 1.5e-83
Smith-Waterman score: 1625; 67.6% identity (89.8% similar) in 343 aa overlap (1-342:1-343)
10 20 30 40 50
pF1KE0 MTSNFSQP-VVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHF
:..:::: .:.:::..:: :::.:::::: : :::....::..::.::::::: ..:::
NP_778 MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 KQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSV
::::.::::::::::::::::::::: :: ::.:::::::: ..: .:.: :..::..:.
NP_778 KQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 LHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEEL
.::: : .::::.:::::.: :::::::::::: .::.. .::: ..::::.:..:.:::
NP_778 FHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEEL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 VSALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVES
: ::.:::::: ..:.:::. :::::::...:...::::::.::.:: :::.:.:...:
NP_778 VVALTCVGGCQAPLNQNWVLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE0 SSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSA
:::::: ::::::::::::::... ::..::::: :: .:::.:.:.:: :.::: : .
NP_778 SSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCV
250 260 270 280 290 300
300 310 320 330 340
pF1KE0 YYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE
::::::::::::.:: :: ::::::.:: ::...::: .:: :
NP_778 YYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVETD
310 320 330 340
>>NP_003958 (OMIM: 607405) trace amine-associated recept (337 aa)
initn: 1063 init1: 690 opt: 1019 Z-score: 1022.5 bits: 197.6 E(85289): 3.3e-50
Smith-Waterman score: 1019; 44.1% identity (73.7% similar) in 331 aa overlap (12-342:16-337)
10 20 30 40 50
pF1KE0 MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSV
.::. ::::: .: .. : ....: : . : :. :.::..: .:
NP_003 MRAVFIQGAEEHPAAFCYQ-VNGSCPRTVHTLGIQLVIYLACAAGMLIIVLGNVFVAFAV
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LHFKQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCY
.:: ::.:::::. ::: ::...:. :. .: .:.:::::.:: .: ::. :. ::
NP_003 SYFKALHTPTNFLLLSLALADMFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 SSVLHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGL
.:..::::: :::. .. :::.: .:::: :. : ..: .: .:.. .:: : . :
NP_003 TSIFHLCFISIDRHCAICDPLLYPSKFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 EELVSALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSK
. . . :::.::..... : ..: :::.: :.:: :: :::..: .:: .: : :..
NP_003 SQWLEEMPCVGSCQLLLNKFWGWLNFPLFFVPCLIMISLYVKIFVVATRQAQQITTLSKS
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 VESSSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICC
. .. ::.:::::::::..: ... :::.:.: ..:... :.:: ...:
NP_003 LAGA--------AKHERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFI
240 250 260 270 280 290
300 310 320 330 340
pF1KE0 WSAYYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE
: ::.::: ::.::.. : :::::.:: :: :.. .. :..:. :
NP_003 WFAYFNSACNPIIYVFSYQWFRKALKLTLSQKVFSPQTRTVDLYQE
300 310 320 330
>>NP_612200 (OMIM: 609333) trace amine-associated recept (339 aa)
initn: 887 init1: 481 opt: 920 Z-score: 924.7 bits: 179.5 E(85289): 9.2e-45
Smith-Waterman score: 920; 39.3% identity (71.4% similar) in 336 aa overlap (9-342:1-336)
10 20 30 40 50 60
pF1KE0 MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFK
.. .:.. .: ::... .: :. ::. . . : .. :::.:..:. :::
NP_612 MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFK
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 QLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVL
:::.:::.:: :.: .:::.: :: .::::..: ::::: :: .:. :. . .:..
NP_612 QLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIF
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 HLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELV
:: :: :::: .: ::: : .:... : . : .:: .: ... .... .: : ::.
NP_612 HLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIY
120 130 140 150 160 170
190 200 210 220 230
pF1KE0 -SALNCVGGCQIIVSQGWVLIDFLL-FFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVE
. ..: :::... :. .. :. :.:: .:. .: .:.::::.:: : ...:..
NP_612 YKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQ
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 SSSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWS
. : . ..::::.::::... .:.: : :. . ..: :. .. : . .. :
NP_612 IGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWF
240 250 260 270 280 290
300 310 320 330 340
pF1KE0 AYYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE
.: ::..::..::.::::::::.:..: : ... .:: .::::
NP_612 GYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
300 310 320 330
>>NP_001028252 (OMIM: 604849) trace amine-associated rec (351 aa)
initn: 846 init1: 516 opt: 851 Z-score: 856.3 bits: 166.9 E(85289): 5.9e-41
Smith-Waterman score: 851; 38.5% identity (68.6% similar) in 322 aa overlap (13-332:25-337)
10 20 30 40
pF1KE0 MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSL-LAVF
: : : :: :. : : :: .:. : ::. ...:
NP_001 MAVSSEQHELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYS-FMAGSIFITIF
10 20 30 40 50
50 60 70 80 90 100
pF1KE0 GNLLVMTSVLHFKQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLH
::: .. :. .:::::.:::::: :.: .:::.: :.: .::.:.::.::::: :: ..
NP_001 GNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIY
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE0 SCCDVAFCYSSVLHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVF
:. . .:..::: . :::. .. ::.:.::.:. : . . : .: ... .:
NP_001 YSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVV
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE0 YTGVNDDGLEELVSALNCVGGCQIIVSQGWVLIDFLL-FFIPTLVMIILYSKIFLIAKQQ
.. . ::.: . : ..: .. .. : :. :: : .:. .:.::: .....
NP_001 FSEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKH
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE0 AIKIETTSSKVESSSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFL
: ... :. . .: :...:::::::... .:.. :.: ::.: :..:
NP_001 A-------HAINNLRENQNNQV-KKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE0 TPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE
::. ... : .:.::. :::::..::::::.:.: :: : ....
NP_001 TPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
300 310 320 330 340 350
>>NP_055441 (OMIM: 604849) trace amine-associated recept (306 aa)
initn: 801 init1: 471 opt: 800 Z-score: 806.6 bits: 157.5 E(85289): 3.5e-38
Smith-Waterman score: 800; 37.9% identity (69.8% similar) in 298 aa overlap (37-332:3-292)
10 20 30 40 50 60
pF1KE0 QPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSL-LAVFGNLLVMTSVLHFKQLHSP
.: ::. ...:::: .. :. .:::::.:
NP_055 MYSFMAGSIFITIFGNLAMIISISYFKQLHTP
10 20 30
70 80 90 100 110 120
pF1KE0 TNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFI
::::: :.: .:::.: :.: .::.:.::.::::: :: .. :. . .:..::: .
NP_055 TNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE0 CIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNC
:::. .. ::.:.::.:. : . . : .: ... .: .. . ::.: . :
NP_055 AIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILVAC
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE0 VGGCQIIVSQGWVLIDFLL-FFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESSSESY
..: .. .. : :. :: : .:. .:.::: .....: ... :.
NP_055 SSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHA-------HAINNLRENQ
160 170 180 190 200
250 260 270 280 290 300
pF1KE0 KIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSA
. .: :...:::::::... .:.. :.: ::.: :..: ::. ... : .:.::.
NP_055 NNQV-KKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNST
210 220 230 240 250 260
310 320 330 340
pF1KE0 MNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE
:::::..::::::.:.: :: : ....
NP_055 CNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
270 280 290 300
>>XP_016868585 (OMIM: 104221) PREDICTED: alpha-1A adrene (317 aa)
initn: 411 init1: 294 opt: 407 Z-score: 418.1 bits: 85.7 E(85289): 1.5e-16
Smith-Waterman score: 428; 31.4% identity (57.8% similar) in 287 aa overlap (18-273:11-288)
10 20 30 40 50
pF1KE0 MTSNFSQPVVQLCYEDVNGSCIETPYSPG-SRVILYTAFSFGSLL-AVFGNLLVMTSVLH
...: . : . :..:: .. : .: .:.::.::. ::
XP_016 MVFLSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVAC
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 FKQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSS
..::: :.. :..:: ::.:. ::. :: . : . : :: ::.. . :: : .:
XP_016 HRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTAS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 VLHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYS-GAVFYTGVNDDGLE
.. ::.: ::::: :. :: : : : . . . : : :. : : .: : .
XP_016 IMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLF-------GWR
120 130 140 150 160
180 190 200 210 220 230
pF1KE0 ELVSALNCVGGCQIIVSQGWVLIDFL-LFFIPTLVMIILYSKIFLIAKQQAIKIETTSSK
. . . . ::: :.::.. : :..: .....: .....::... ... .
XP_016 QPAPEDETI--CQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKT
170 180 190 200 210 220
240 250 260
pF1KE0 VESSSESYKIRVAK---------------------------RERKAAKTLGVTVLAFVIS
.:.::. .:. . ::.:::::::..: ::.
XP_016 DKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLC
230 240 250 260 270 280
270 280 290 300 310 320
pF1KE0 WLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLILSGDV
:::.
XP_016 WLPFFLVMPIGKKMKKLKVPWPEEGHRRKLTLS
290 300 310
>>NP_001035262 (OMIM: 602164) 5-hydroxytryptamine recept (360 aa)
initn: 461 init1: 206 opt: 405 Z-score: 415.6 bits: 85.4 E(85289): 2.1e-16
Smith-Waterman score: 583; 32.1% identity (64.5% similar) in 327 aa overlap (16-328:5-330)
10 20 30 40 50 60
pF1KE0 MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFK
:.: : : .. .:.: : .: :.:..::::::..: .
NP_001 MDKLDANVSS-EEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDR
10 20 30 40
70 80 90 100 110
pF1KE0 QLHS-PTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSV
::.. ::..:.::: ::.::.: :: :. .. :.. : .: :: ... :: . .:.
NP_001 QLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASI
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE0 LHLCFICIDRYIVVT-DPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEE
.::: : .::: .. .:::: .:.: .. .. :..: : .. : :. :. .
NP_001 FHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIID
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE0 LVSA--LNCVGG---CQIIVSQGWVLI-DFLLFFIPTLVMIILYSKIFLIAKQQAIKIE-
:. .: .. : ..:.. ... . . :.:: :.:.. : .:.. ::..: .:.
NP_001 LIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQM
170 180 190 200 210 220
240 250 260 270 280
pF1KE0 -----TTSSKVESSSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFL
..: . .:..... . . : :::::: . . : . : :. : ..: :. .
NP_001 LQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYT
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE0 TPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE
.:. .. : .: ::..::..::.. ::.:. .:: :
NP_001 VPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCST
290 300 310 320 330 340
NP_001 TTINGSTHVLRF
350 360
>>NP_955525 (OMIM: 602164) 5-hydroxytryptamine receptor (378 aa)
initn: 438 init1: 206 opt: 405 Z-score: 415.3 bits: 85.4 E(85289): 2.1e-16
Smith-Waterman score: 583; 32.1% identity (64.5% similar) in 327 aa overlap (16-328:5-330)
10 20 30 40 50 60
pF1KE0 MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFK
:.: : : .. .:.: : .: :.:..::::::..: .
NP_955 MDKLDANVSS-EEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDR
10 20 30 40
70 80 90 100 110
pF1KE0 QLHS-PTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSV
::.. ::..:.::: ::.::.: :: :. .. :.. : .: :: ... :: . .:.
NP_955 QLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASI
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE0 LHLCFICIDRYIVVT-DPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEE
.::: : .::: .. .:::: .:.: .. .. :..: : .. : :. :. .
NP_955 FHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIID
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE0 LVSA--LNCVGG---CQIIVSQGWVLI-DFLLFFIPTLVMIILYSKIFLIAKQQAIKIE-
:. .: .. : ..:.. ... . . :.:: :.:.. : .:.. ::..: .:.
NP_955 LIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQM
170 180 190 200 210 220
240 250 260 270 280
pF1KE0 -----TTSSKVESSSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFL
..: . .:..... . . : :::::: . . : . : :. : ..: :. .
NP_955 LQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYT
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE0 TPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE
.:. .. : .: ::..::..::.. ::.:. .:: :
NP_955 VPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCST
290 300 310 320 330 340
NP_955 TTINGSTHVLSGCSPVSSFLLLFCNRPVPV
350 360 370
342 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 03:32:31 2016 done: Sat Nov 5 03:32:32 2016
Total Scan time: 7.500 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]