FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0843, 353 aa 1>>>pF1KE0843 353 - 353 aa - 353 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8271+/-0.000446; mu= 19.0199+/- 0.028 mean_var=63.2031+/-13.033, 0's: 0 Z-trim(109.9): 88 B-trim: 0 in 0/51 Lambda= 0.161326 statistics sampled from 18070 (18146) to 18070 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.557), E-opt: 0.2 (0.213), width: 16 Scan time: 7.020 The best scores are: opt bits E(85289) NP_065684 (OMIM: 605234) vomeronasal type-1 recept ( 353) 2389 565.0 8.8e-161 NP_076411 (OMIM: 604790) taste receptor type 2 mem ( 317) 214 58.7 2e-08 XP_011515565 (OMIM: 188545) PREDICTED: thyrotropin ( 398) 160 46.3 0.00014 NP_003292 (OMIM: 188545) thyrotropin-releasing hor ( 398) 160 46.3 0.00014 NP_076408 (OMIM: 604793) taste receptor type 2 mem ( 318) 156 45.2 0.00023 NP_795364 (OMIM: 613965) taste receptor type 2 mem ( 307) 140 41.5 0.0029 NP_076407 (OMIM: 604794) taste receptor type 2 mem ( 309) 134 40.1 0.0078 NP_001718 (OMIM: 300107) bombesin receptor subtype ( 399) 134 40.2 0.0095 >>NP_065684 (OMIM: 605234) vomeronasal type-1 receptor 1 (353 aa) initn: 2389 init1: 2389 opt: 2389 Z-score: 3007.5 bits: 565.0 E(85289): 8.8e-161 Smith-Waterman score: 2389; 100.0% identity (100.0% similar) in 353 aa overlap (1-353:1-353) 10 20 30 40 50 60 pF1KE0 MVGDTLKLLSPLMTRYFFLLFYSTDSSDLNENQHPLDFDEMAFGKVKSGISFLIQTGVGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 MVGDTLKLLSPLMTRYFFLLFYSTDSSDLNENQHPLDFDEMAFGKVKSGISFLIQTGVGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 LGNSFLLCFYNLILFTGHKLRPTDLILSQLALANSMVLFFKGIPQTMAAFGLKYLLNDTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 LGNSFLLCFYNLILFTGHKLRPTDLILSQLALANSMVLFFKGIPQTMAAFGLKYLLNDTG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 CKFVFYYHRVGTRVSLSTICLLNGFQAIKLNPSICRWMEIKIRSPRFIDFCCLLCWAPHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 CKFVFYYHRVGTRVSLSTICLLNGFQAIKLNPSICRWMEIKIRSPRFIDFCCLLCWAPHV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LMNASVLLLVNGPLNSKNSSAKNNYGYCSYKASKRFSSLHAVLYFSPDFMSLGFMVWASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 LMNASVLLLVNGPLNSKNSSAKNNYGYCSYKASKRFSSLHAVLYFSPDFMSLGFMVWASG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 SMVFFLYRHKQQVQHNHSNRLSCRPSQEARATHTIMVLVSSFFVFYSVHSFLTIWTTVVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 SMVFFLYRHKQQVQHNHSNRLSCRPSQEARATHTIMVLVSSFFVFYSVHSFLTIWTTVVA 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 NPGQWIVTNSVLVASCFPARSPFVLIMSDTHISQFCFACRTRKTLFPNLVVMP ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 NPGQWIVTNSVLVASCFPARSPFVLIMSDTHISQFCFACRTRKTLFPNLVVMP 310 320 330 340 350 >>NP_076411 (OMIM: 604790) taste receptor type 2 member (317 aa) initn: 110 init1: 63 opt: 214 Z-score: 272.4 bits: 58.7 E(85289): 2e-08 Smith-Waterman score: 214; 24.0% identity (55.9% similar) in 304 aa overlap (44-334:3-289) 20 30 40 50 60 70 pF1KE0 TRYFFLLFYSTDSSDLNENQHPLDFDEMAFGKVKSGISF--LIQTGVGILGNSFLLCFYN : .:: ..: ... .: :::::. NP_076 MGGVIKSIFTFVLIVEFIIGNLGNSFIALVNC 10 20 30 80 90 100 110 120 130 pF1KE0 LILFTGHKLRPTDLILSQLALAN-SMVLFFKGIPQTMAAFGLKYLLNDTGCKFVFYYHRV . :.:. .: ::. ::.. :.: .. : ...: . .. ... : NP_076 IDWVKGRKISSVDRILTALAISRISLVWLIFG-SWCVSVFFPALFATEKMFRMLTNIWTV 40 50 60 70 80 90 140 150 160 170 180 pF1KE0 GTRVSLSTICLLNGFQAIKL-NPSICRWMEIKIRSPRFIDFCCLLCWAPHVLMNASVLLL .. :. :. : .:. : : .. .: : . . . :: . ...: . : NP_076 INHFSVWLATGLGTFYFLKIANFSNSIFLYLKWRVKKVV-LVLLLVTSVFLFLNIA---L 100 110 120 130 140 190 200 210 220 230 240 pF1KE0 VNGPLNSKNSSAKNNYGYCSYKASK--RFSSL----HAVLYFSPDFMSLGFMVWASGSMV .: .:.. .. . : :: .:. ::::: .:. : : .::.... .. NP_076 INIHINASINGYRRNKT-CSSDSSNFTRFSSLIVLTSTVFIFIPFTLSLAMFLL----LI 150 160 170 180 190 200 250 260 270 280 290 300 pF1KE0 FFLYRHKQQVQHNHSNRLSCRPSQEARATHTIMVLVSSFFVFYSVHS---FLTIWTTVVA : ...:....: :. ..: : .: : . : .::..:.. : :...::. NP_076 FSMWKHRKKMQ--HTVKISGDASTKA---HRGVKSVITFFLLYAIFSLSFFISVWTSERL 210 220 230 240 250 310 320 330 340 350 pF1KE0 NPGQWIVTNSVLVASCFPARSPFVLIMSDTHISQFCFACRTRKTLFPNLVVMP . . :... . .: .:. :::... .. : NP_076 EENLIILSQVMGMA--YPSCHSCVLILGNKKLRQASLSVLLWLRYMFKDGEPSGHKEFRE 260 270 280 290 300 310 NP_076 SS >>XP_011515565 (OMIM: 188545) PREDICTED: thyrotropin-rel (398 aa) initn: 137 init1: 86 opt: 160 Z-score: 203.1 bits: 46.3 E(85289): 0.00014 Smith-Waterman score: 173; 21.8% identity (52.1% similar) in 357 aa overlap (27-347:7-345) 10 20 30 40 50 pF1KE0 MVGDTLKLLSPLMTRYFFLLFYSTDSSDLNENQ-HPLDFDEMAFGKVKSGISFLIQTGVG :.::..: .: . . .: . . :: :.: XP_011 MENETVSELNQTQLQPRAVVALEY-QVVTILLVLIICGLG 10 20 30 60 70 80 90 100 110 pF1KE0 ILGNSFLLCFYNLILFTGHKLRPTDLILSQLALANSMVLFFKGIPQTMAAFGLKYLLNDT :.:: ... ... : : ::. : .::.:. ::: :.:. .. ... . . XP_011 IVGNIMVVL---VVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYV 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 GCKFVFYYHRVGTRVSLSTICLLNGFQAIKLNPSICRWMEIKI-----RSPRFIDFCCLL :: . : . .: .: : ...: .:. .::. .. .. :. ..: : XP_011 GCLCITYLQYLGINASS---CSITAF-TIERYIAICHPIKAQFLCTFSRAKKIIIFV--- 100 110 120 130 140 180 190 200 210 220 pF1KE0 CWAPHVLMNASVLLLVNGPLNSKNSSAKNNYGYCSYKASKRFSSL-----HAVLYFSPDF :: :. ..:.. ... ... . :.:: :. . : .:.: : XP_011 -WAFTSLYCMLWFFLLDLNISTYKDAIVIS---CGYKISRNYYSPIYLMDFGVFYVVP-- 150 160 170 180 190 200 230 240 250 260 270 pF1KE0 MSLGFMVWASGSMVFFL-------------YRHKQQVQH-----NHSNR-LSCRPSQEAR : :. .... . ..:: ... . :. : ::: .. :.. . XP_011 MILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSRKQ 210 220 230 240 250 260 280 290 300 310 320 pF1KE0 ATHTIMVLVSSFFVFYSVHSFLTIWTTVVANPGQ--WIVTNSVLVASCFPARSPFVL-IM .:. . :.: : ... . :.. .. ...: : :.. . : .: . .: XP_011 VTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLM 270 280 290 300 310 320 330 340 350 pF1KE0 SDTHISQF---CFACRTRKTLFPNLVVMP :. . : : :. . : : XP_011 SQKFRAAFRKLC-NCKQKPTEKPANYSVALNYSVIKESDHFSTELDDITVTDTYLSATKV 330 340 350 360 370 380 >>NP_003292 (OMIM: 188545) thyrotropin-releasing hormone (398 aa) initn: 137 init1: 86 opt: 160 Z-score: 203.1 bits: 46.3 E(85289): 0.00014 Smith-Waterman score: 173; 21.8% identity (52.1% similar) in 357 aa overlap (27-347:7-345) 10 20 30 40 50 pF1KE0 MVGDTLKLLSPLMTRYFFLLFYSTDSSDLNENQ-HPLDFDEMAFGKVKSGISFLIQTGVG :.::..: .: . . .: . . :: :.: NP_003 MENETVSELNQTQLQPRAVVALEY-QVVTILLVLIICGLG 10 20 30 60 70 80 90 100 110 pF1KE0 ILGNSFLLCFYNLILFTGHKLRPTDLILSQLALANSMVLFFKGIPQTMAAFGLKYLLNDT :.:: ... ... : : ::. : .::.:. ::: :.:. .. ... . . NP_003 IVGNIMVVL---VVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYV 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 GCKFVFYYHRVGTRVSLSTICLLNGFQAIKLNPSICRWMEIKI-----RSPRFIDFCCLL :: . : . .: .: : ...: .:. .::. .. .. :. ..: : NP_003 GCLCITYLQYLGINASS---CSITAF-TIERYIAICHPIKAQFLCTFSRAKKIIIFV--- 100 110 120 130 140 180 190 200 210 220 pF1KE0 CWAPHVLMNASVLLLVNGPLNSKNSSAKNNYGYCSYKASKRFSSL-----HAVLYFSPDF :: :. ..:.. ... ... . :.:: :. . : .:.: : NP_003 -WAFTSLYCMLWFFLLDLNISTYKDAIVIS---CGYKISRNYYSPIYLMDFGVFYVVP-- 150 160 170 180 190 200 230 240 250 260 270 pF1KE0 MSLGFMVWASGSMVFFL-------------YRHKQQVQH-----NHSNR-LSCRPSQEAR : :. .... . ..:: ... . :. : ::: .. :.. . NP_003 MILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSRKQ 210 220 230 240 250 260 280 290 300 310 320 pF1KE0 ATHTIMVLVSSFFVFYSVHSFLTIWTTVVANPGQ--WIVTNSVLVASCFPARSPFVL-IM .:. . :.: : ... . :.. .. ...: : :.. . : .: . .: NP_003 VTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLM 270 280 290 300 310 320 330 340 350 pF1KE0 SDTHISQF---CFACRTRKTLFPNLVVMP :. . : : :. . : : NP_003 SQKFRAAFRKLC-NCKQKPTEKPANYSVALNYSVIKESDHFSTELDDITVTDTYLSATKV 330 340 350 360 370 380 >>NP_076408 (OMIM: 604793) taste receptor type 2 member (318 aa) initn: 137 init1: 73 opt: 156 Z-score: 199.4 bits: 45.2 E(85289): 0.00023 Smith-Waterman score: 156; 22.0% identity (52.6% similar) in 304 aa overlap (45-332:4-292) 20 30 40 50 60 70 pF1KE0 RYFFLLFYSTDSSDLNENQHPLDFDEMAFGKVKSGISFLI--QTGVGILGNSFLLCFYNL ::.. . :: . .::::::.:. . NP_076 MADKVQTTLLFLAVGEFSVGILGNAFIGLVNCM 10 20 30 80 90 100 110 120 130 pF1KE0 ILFTGHKLRPTDLILSQLALANSMVLFFKGIPQTMAAFGLKYLLNDTGCKFVFYYHRVGT .:. ::::..::.. .: . . .. . ... .. . . NP_076 DWVKKRKIASIDLILTSLAISRICLLCVILLDCFILVLYPDVYATGKEMRIIDFFWTLTN 40 50 60 70 80 90 140 150 160 170 180 pF1KE0 RVSLSTICLLNGFQAIKL----NPSICRWMEIKIRSPRFIDFCCLLCWAPHVLMNASVLL ..:. :. . .:. .: . :: : : : :.. : : . :... . NP_076 HLSIWFATCLSIYYFFKIGNFFHP-LFLWM--KWRIDRVISWILLGCVVLSVFISLPATE 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE0 LVNGPLN-SKNSSAKNNYGY-C-----SYKASKRFSSLHAVLYFSPDFMSLGFMVWASGS .:. . ... :.: . : .. ..: : .: ..: : .::. :. NP_076 NLNADFRFCVKAKRKTNLTWSCRVNKTQHASTKLFLNLATLLPFCVCLMSF-FL------ 160 170 180 190 200 250 260 270 280 290 pF1KE0 MVFFLYRHKQQVQHNHSNRLSCR-PSQEA--RATHTIMVLVSSFFVFYSVHSFLTIWTTV ... : :: ...: . .. :: :: :: :: .... .. :...: ::: .. NP_076 LILSLRRHIRRMQLSATG---CRDPSTEAHVRALKAVISFLLLFIAYYL--SFLIATSSY 210 220 230 240 250 300 310 320 330 340 350 pF1KE0 VANPGQWIVTNSVLVASCFPARSPFVLIMSDTHISQFCFACRTRKTLFPNLVVMP . : . .: .:. :.::...... NP_076 FMPETELAVIFGESIALIYPSSHSFILILGNNKLRHASLKVIWKVMSILKGRKFQQHKQI 260 270 280 290 300 310 >>NP_795364 (OMIM: 613965) taste receptor type 2 member (307 aa) initn: 79 init1: 53 opt: 140 Z-score: 179.5 bits: 41.5 E(85289): 0.0029 Smith-Waterman score: 140; 23.4% identity (52.2% similar) in 299 aa overlap (52-332:13-290) 30 40 50 60 70 80 pF1KE0 YSTDSSDLNENQHPLDFDEMAFGKVKSGISFLIQTGVGILGNSFLLCFYNLILFTGHKLR : . . .:: .:.:.. . . .: NP_795 MQAALTAFFVLLFSLLSLLGIAANGFIVLVLGREWLRYGRLL 10 20 30 40 90 100 110 120 130 140 pF1KE0 PTDLILSQLALANSMVLFFKGIPQTMAAFGLKYLLNDTGCKFVFYYHRVGTRVSLSTIC- : :.:: .:. :. . : . : ... . : . . :. : . .: NP_795 PLDMILISLG-ASRFCLQLVGTVHNFYYSAQKVEYSGGLGRQFFHLHWHFLNSATFWFCS 50 60 70 80 90 100 150 160 170 180 190 pF1KE0 LLNGFQAIKL-NPSICRWMEIKIRSPRFIDFCCLLCWAPHVLMNASVLLL---VNGPLNS :. . .:. : . .. .: : : .. . : ::.. . :: :: :. NP_795 WLSVLFCVKIANITHSTFLWLKWRFPGWVPWLLL----GSVLISFIITLLFFWVNYPVY- 110 120 130 140 150 200 210 220 230 240 pF1KE0 KNSSAKNNYGYCSYKASKRFSSLHAVLYFSPDFMSLGFMVWASGSMVFF---------LY .. .. : .:: . :. . :. : :: ...:. ::. : NP_795 QEFLIRKFSGNMTYKWNTRIET-----YYFP---SLKLVIWSIPFSVFLVSIMLLINSLR 160 170 180 190 200 250 260 270 280 290 300 pF1KE0 RHKQQVQHN-HSNRLSCRPSQEARATHTIMVLVSSFFVFYSVHSFLTIWTTV---VANPG :: :..::: :: . :: .:. :... :.: :...:.. :::.. . .. . NP_795 RHTQRMQHNGHSLQ---DPSTQAH-TRALKSLIS-FLILYAL-SFLSLIIDAAKFISMQN 210 220 230 240 250 260 310 320 330 340 350 pF1KE0 QWIVTNSVLVASCFPARSPFVLIMSDTHISQFCFACRTRKTLFPNLVVMP .. .. : :. .. ::.::.:. .. NP_795 DFYWPWQIAVYLCISVH-PFILIFSNLKLRSVFSQLLLLARGFWVA 270 280 290 300 >>NP_076407 (OMIM: 604794) taste receptor type 2 member (309 aa) initn: 100 init1: 59 opt: 134 Z-score: 171.9 bits: 40.1 E(85289): 0.0078 Smith-Waterman score: 134; 21.9% identity (52.6% similar) in 302 aa overlap (58-340:19-303) 30 40 50 60 70 80 pF1KE0 DLNENQHPLDFDEMAFGKVKSGISFLIQTGVGILGNSFLLCFYNLILFTGHKLRPTDLIL .:::::... . . .:. .: :: NP_076 MFSPADNIFIILITGEFILGILGNGYIALVNWIDWIKKKKISTVDYIL 10 20 30 40 90 100 110 120 130 140 pF1KE0 SQLALANSMVLFFKGIPQTMAAFGLKYLLN-DTGCK-----FVFYYHRVGTRVSLSTICL ..:..: .. ..:.. :. .:: :. : .: . .. ... NP_076 TNLVIARICLI------SVMVVNGIVIVLNPDVYTKNKQQIVIFTFWTFANYLNMWITTC 50 60 70 80 90 100 150 160 170 180 190 pF1KE0 LNGFQAIKLNPS---ICRWMEIKIRSPRFIDFCCLLCWAPHVLMN--ASVLLLVNGPLNS :: : .:. : . :.. :: . . : :.: .:.. :...: . ... NP_076 LNVFYFLKIASSSHPLFLWLKWKI--DMVVHWILLGCFAISLLVSLIAAIVLSCDYRFHA 110 120 130 140 150 160 200 210 220 230 240 250 pF1KE0 KNSSAKNNYGYCSYKASKRFSSLHAVLYFS--PDFMSL-GFMVWASGSMVFFLYRHKQQV . .: . . : : :. : ..:: .:.. .: :.:: .:. NP_076 IAKHKRNITEMFHVSKIPYFEPLTLFNLFAIVPFIVSLISFFL-----LVRSLWRHTKQI 170 180 190 200 210 260 270 280 290 300 310 pF1KE0 QHNHSNRLSCRPSQEA--RATHTIMVLVSSFFVFYSVHSFLTIWTTVVANPGQWIVTNSV . .. : :: :. :: .:. .. ::..: . :.: .. .... . : . NP_076 KLYATG--SRDPSTEVHVRAIKTMTSFIFFFFLYY-ISSILMTFSYLMTKY-KLAVEFGE 220 230 240 250 260 270 320 330 340 350 pF1KE0 LVASCFPARSPFVLIMSDTHISQ-FC--FACRTRKTLFPNLVVMP ..: .: ..::. .... : : ..:: NP_076 IAAILYPLGHSLILIVLNNKLRQTFVRMLTCRKIACMI 280 290 300 >>NP_001718 (OMIM: 300107) bombesin receptor subtype-3 [ (399 aa) initn: 107 init1: 46 opt: 134 Z-score: 170.3 bits: 40.2 E(85289): 0.0095 Smith-Waterman score: 134; 20.8% identity (56.2% similar) in 322 aa overlap (50-347:52-356) 20 30 40 50 60 70 pF1KE0 LFYSTDSSDLNENQHPLDFDEMAFGKVKSGISFLIQTGVGILGNSFLLCFYNLILFTGHK :.. . .::::::..:. ..: .. NP_001 SSSSVVSNDNTNKGWSGDNSPGIEALCAIYITYAVIISVGILGNAILI----KVFFKTKS 30 40 50 60 70 80 90 100 110 120 130 pF1KE0 LRPT-DLILSQLALANSMVLFFKGIPQTMAAFGLK-YLLNDTGCKFVFYYHRVGTRVSLS .. . ......::... ..:.. .: . . . .:.. ::: . . . ... ::. NP_001 MQTVPNIFITSLAFGD-LLLLLTCVPVDATHYLAEGWLFGRIGCKVLSFIRLTSVGVSVF 80 90 100 110 120 130 140 150 160 170 180 190 pF1KE0 TICLLNG--FQAIKLNPSICRWMEIKIRSPRFIDFCCLL-C-WAPHVLMNASVLLLVNGP :. .:.. ..:. ..: .: . : .. : : : ... .. : NP_001 TLTILSADRYKAV-VKP-----LE-RQPSNAILKTCVKAGCVWIVSMIFALPEAIFSN-V 140 150 160 170 180 200 210 220 230 240 250 pF1KE0 LNSKNSSAKNNYGYC-SYKASKRF-SSLHAVLYFSPDFM-SLGFMVWASGSMVFFLYRHK . .. . . .. : :: .::.. . .:..: : .. :... . .. ::. NP_001 YTFRDPNKNMTFESCTSYPVSKKLLQEIHSLLCFLVFYIIPLSIISVYYSLIARTLYKST 190 200 210 220 230 240 260 270 280 290 300 pF1KE0 QQVQHNHSNRLSCRPSQEARATHTIMVLVSSF-------FVFYSVHSFLTIWTTVVANPG .. ..... . .. : ..:..:::. : ..: ::: : : : . NP_001 LNIPTEEQSHARKQIESRKRIARTVLVLVALFALCWLPNHLLYLYHSF-TSQTYVDPSAM 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 QWIVT--NSVLV--ASCFPARSPFVLI-MSDTHISQF---CFACRTRKTLFPNLVVMP ..: : . ::. :: .::.: .: . ..: : :.... : NP_001 HFIFTIFSRVLAFSNSCV---NPFALYWLSKSFQKHFKAQLFCCKAERPEPPVADTSLTT 310 320 330 340 350 360 NP_001 LAVMGTVPGTGSIQMSEISVTSFTGCSVKQAEDRF 370 380 390 353 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 03:33:07 2016 done: Sat Nov 5 03:33:08 2016 Total Scan time: 7.020 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]