FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0844, 301 aa 1>>>pF1KE0844 301 - 301 aa - 301 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7093+/-0.00044; mu= 12.5614+/- 0.027 mean_var=66.0252+/-13.807, 0's: 0 Z-trim(110.6): 81 B-trim: 1116 in 1/50 Lambda= 0.157841 statistics sampled from 18987 (19044) to 18987 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.588), E-opt: 0.2 (0.223), width: 16 Scan time: 6.540 The best scores are: opt bits E(85289) NP_065684 (OMIM: 605234) vomeronasal type-1 recept ( 353) 815 194.8 2.1e-49 NP_003982 (OMIM: 131244,277580,600155,600501) endo ( 436) 161 45.9 0.00017 NP_000106 (OMIM: 131244,277580,600155,600501) endo ( 442) 161 45.9 0.00017 NP_001116131 (OMIM: 131244,277580,600155,600501) e ( 442) 161 45.9 0.00017 NP_001188326 (OMIM: 131244,277580,600155,600501) e ( 532) 161 45.9 0.0002 NP_001718 (OMIM: 300107) bombesin receptor subtype ( 399) 148 42.9 0.0012 NP_795364 (OMIM: 613965) taste receptor type 2 mem ( 307) 140 41.1 0.0034 >>NP_065684 (OMIM: 605234) vomeronasal type-1 receptor 1 (353 aa) initn: 800 init1: 468 opt: 815 Z-score: 1008.0 bits: 194.8 E(85289): 2.1e-49 Smith-Waterman score: 815; 43.1% identity (70.6% similar) in 299 aa overlap (1-298:41-338) 10 20 pF1KE0 MASRYVAVGM-ILSQTVVGVLGSFSVLLHY :: : :. .: :: ::.::. .: : NP_065 PLMTRYFFLLFYSTDSSDLNENQHPLDFDEMAFGKVKSGISFLIQTGVGILGNSFLLCFY 20 30 40 50 60 70 30 40 50 60 70 80 pF1KE0 LSFYCTGCRLRSTDLIVKHLIVANFLALRCKGVPQTMAAFGVRYFLNALGCKLVFYLHRV . :: .:: ::::...: .:: ..: ::.::::::::..:.:: :::.::: ::: NP_065 NLILFTGHKLRPTDLILSQLALANSMVLFFKGIPQTMAAFGLKYLLNDTGCKFVFYYHRV 80 90 100 110 120 130 90 100 110 120 130 140 pF1KE0 GRGVSIGTTCLLSVFQVITVSSRKSRWAKLKEKAPKHVGFSVLLCWIVCMLVNIIFPMYV : ::..: :::. ::.: .. :: ..: ..:. . : :::: .:.: . : NP_065 GTRVSLSTICLLNGFQAIKLNPSICRWMEIKIRSPRFIDFCCLLCWAPHVLMNASVLLLV 140 150 160 170 180 190 150 160 170 180 190 200 pF1KE0 TGKWNYTNITVNEDLGYCSGGGNNKIAQTLRAMLLSFPDVLCLGLMLWVSSSMVCILHRH .: : : ..... :::: ...... .:.:.: :: . ::.:.:.:.::: .:.:: NP_065 NGPLNSKNSSAKNNYGYCSYKASKRFS-SLHAVLYFSPDFMSLGFMVWASGSMVFFLYRH 200 210 220 230 240 210 220 230 240 250 260 pF1KE0 KQRVQHIDRSNLSPRASPENRATQSILILVSTFVSSYTLSCLFQVCMALLDNPNSLLVNT ::.::: . :: : : : :::..:..:::.: :.. .. . ... ::.. .:.. NP_065 KQQVQHNHSNRLSCRPSQEARATHTIMVLVSSFFVFYSVHSFLTIWTTVVANPGQWIVTN 250 260 270 280 290 300 270 280 290 300 pF1KE0 SALMSVCFPTLSPFVLMSCDPSVYRFCFAWKR :.:.. :::. :::::. : . .:::: NP_065 SVLVASCFPARSPFVLIMSDTHISQFCFACRTRKTLFPNLVVMP 310 320 330 340 350 >>NP_003982 (OMIM: 131244,277580,600155,600501) endothel (436 aa) initn: 93 init1: 72 opt: 161 Z-score: 201.7 bits: 45.9 E(85289): 0.00017 Smith-Waterman score: 161; 22.0% identity (55.6% similar) in 304 aa overlap (16-297:113-397) 10 20 30 40 pF1KE0 MASRYVAVGMILSQTVVGVLGSFSVLLHYLSFYCTGCRLRSTDLI :.:..:. :.::. . : . : . ... NP_003 RTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGN-STLLRII--YKNKCMRNGPNIL 90 100 110 120 130 50 60 70 80 90 100 pF1KE0 VKHLIVANFLALRCKGVP-QTMAAFGVRYFLNALGCKLVFYLHRVGRGVSIGTTCLLSVF . : ....: . .: ... .. . ..: :::: ...... :... . : ::. NP_003 IASLALGDLLHI-VIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSID 140 150 160 170 180 190 110 120 130 140 150 160 pF1KE0 QVITVSSRKSRWAKLKE-KAPKHVGFSVLLCWIVCMLVNIIFPMYVTGKWNYTNITVNED . .:.: :...: .:: .. ..: :.: ... . : . .. ::.. NP_003 RYRAVAS----WSRIKGIGVPKWTAVEIVLIWVVSVVLAV--PEAI----GFDIITMDYK 200 210 220 230 240 170 180 190 200 210 pF1KE0 LGY---CSGGGNNKIA--QTLRAM----LLSFPDVLCLGLMLWVSSSMVCILHRHKQRVQ .: : .: : : .. :.:: : :.. . . :.: . :.:. .: NP_003 GSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQ 250 260 270 280 290 300 220 230 240 250 260 270 pF1KE0 HIDRSNLSPRASPENRATQSILILVSTFVSSYT---LSCLFQVCMALLDNPNSLLVNTSA ..:. : ....... :: .:. . :: .... . ..:: . : NP_003 IALNDHLKQR----REVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL-LSF 310 320 330 340 350 360 280 290 300 pF1KE0 LMSVCFPTLSPFVLMSC-DP-SVY----RF--CFAWKR :. . . .. : :: .: ..: :: :: NP_003 LLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKAGPHVGNKLVMLFSVNIECDGTVNQ 370 380 390 400 410 420 NP_003 NPTMWPERKSNNN 430 >>NP_000106 (OMIM: 131244,277580,600155,600501) endothel (442 aa) initn: 93 init1: 72 opt: 161 Z-score: 201.6 bits: 45.9 E(85289): 0.00017 Smith-Waterman score: 161; 22.0% identity (55.6% similar) in 304 aa overlap (16-297:113-397) 10 20 30 40 pF1KE0 MASRYVAVGMILSQTVVGVLGSFSVLLHYLSFYCTGCRLRSTDLI :.:..:. :.::. . : . : . ... NP_000 RTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGN-STLLRII--YKNKCMRNGPNIL 90 100 110 120 130 50 60 70 80 90 100 pF1KE0 VKHLIVANFLALRCKGVP-QTMAAFGVRYFLNALGCKLVFYLHRVGRGVSIGTTCLLSVF . : ....: . .: ... .. . ..: :::: ...... :... . : ::. NP_000 IASLALGDLLHI-VIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSID 140 150 160 170 180 190 110 120 130 140 150 160 pF1KE0 QVITVSSRKSRWAKLKE-KAPKHVGFSVLLCWIVCMLVNIIFPMYVTGKWNYTNITVNED . .:.: :...: .:: .. ..: :.: ... . : . .. ::.. NP_000 RYRAVAS----WSRIKGIGVPKWTAVEIVLIWVVSVVLAV--PEAI----GFDIITMDYK 200 210 220 230 240 170 180 190 200 210 pF1KE0 LGY---CSGGGNNKIA--QTLRAM----LLSFPDVLCLGLMLWVSSSMVCILHRHKQRVQ .: : .: : : .. :.:: : :.. . . :.: . :.:. .: NP_000 GSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQ 250 260 270 280 290 300 220 230 240 250 260 270 pF1KE0 HIDRSNLSPRASPENRATQSILILVSTFVSSYT---LSCLFQVCMALLDNPNSLLVNTSA ..:. : ....... :: .:. . :: .... . ..:: . : NP_000 IALNDHLKQR----REVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL-LSF 310 320 330 340 350 360 280 290 300 pF1KE0 LMSVCFPTLSPFVLMSC-DP-SVY----RF--CFAWKR :. . . .. : :: .: ..: :: :: NP_000 LLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSCLKF 370 380 390 400 410 420 NP_000 KANDHGYDNFRSSNKYSSS 430 440 >>NP_001116131 (OMIM: 131244,277580,600155,600501) endot (442 aa) initn: 93 init1: 72 opt: 161 Z-score: 201.6 bits: 45.9 E(85289): 0.00017 Smith-Waterman score: 161; 22.0% identity (55.6% similar) in 304 aa overlap (16-297:113-397) 10 20 30 40 pF1KE0 MASRYVAVGMILSQTVVGVLGSFSVLLHYLSFYCTGCRLRSTDLI :.:..:. :.::. . : . : . ... NP_001 RTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGN-STLLRII--YKNKCMRNGPNIL 90 100 110 120 130 50 60 70 80 90 100 pF1KE0 VKHLIVANFLALRCKGVP-QTMAAFGVRYFLNALGCKLVFYLHRVGRGVSIGTTCLLSVF . : ....: . .: ... .. . ..: :::: ...... :... . : ::. NP_001 IASLALGDLLHI-VIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSID 140 150 160 170 180 190 110 120 130 140 150 160 pF1KE0 QVITVSSRKSRWAKLKE-KAPKHVGFSVLLCWIVCMLVNIIFPMYVTGKWNYTNITVNED . .:.: :...: .:: .. ..: :.: ... . : . .. ::.. NP_001 RYRAVAS----WSRIKGIGVPKWTAVEIVLIWVVSVVLAV--PEAI----GFDIITMDYK 200 210 220 230 240 170 180 190 200 210 pF1KE0 LGY---CSGGGNNKIA--QTLRAM----LLSFPDVLCLGLMLWVSSSMVCILHRHKQRVQ .: : .: : : .. :.:: : :.. . . :.: . :.:. .: NP_001 GSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQ 250 260 270 280 290 300 220 230 240 250 260 270 pF1KE0 HIDRSNLSPRASPENRATQSILILVSTFVSSYT---LSCLFQVCMALLDNPNSLLVNTSA ..:. : ....... :: .:. . :: .... . ..:: . : NP_001 IALNDHLKQR----REVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL-LSF 310 320 330 340 350 360 280 290 300 pF1KE0 LMSVCFPTLSPFVLMSC-DP-SVY----RF--CFAWKR :. . . .. : :: .: ..: :: :: NP_001 LLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSCLKF 370 380 390 400 410 420 NP_001 KANDHGYDNFRSSNKYSSS 430 440 >>NP_001188326 (OMIM: 131244,277580,600155,600501) endot (532 aa) initn: 93 init1: 72 opt: 161 Z-score: 200.3 bits: 45.9 E(85289): 0.0002 Smith-Waterman score: 161; 22.0% identity (55.6% similar) in 304 aa overlap (16-297:203-487) 10 20 30 40 pF1KE0 MASRYVAVGMILSQTVVGVLGSFSVLLHYLSFYCTGCRLRSTDLI :.:..:. :.::. . : . : . ... NP_001 RTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGN-STLLRII--YKNKCMRNGPNIL 180 190 200 210 220 50 60 70 80 90 100 pF1KE0 VKHLIVANFLALRCKGVP-QTMAAFGVRYFLNALGCKLVFYLHRVGRGVSIGTTCLLSVF . : ....: . .: ... .. . ..: :::: ...... :... . : ::. NP_001 IASLALGDLLHI-VIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSID 230 240 250 260 270 280 110 120 130 140 150 160 pF1KE0 QVITVSSRKSRWAKLKE-KAPKHVGFSVLLCWIVCMLVNIIFPMYVTGKWNYTNITVNED . .:.: :...: .:: .. ..: :.: ... . : . .. ::.. NP_001 RYRAVAS----WSRIKGIGVPKWTAVEIVLIWVVSVVLAV--PEAI----GFDIITMDYK 290 300 310 320 330 170 180 190 200 210 pF1KE0 LGY---CSGGGNNKIA--QTLRAM----LLSFPDVLCLGLMLWVSSSMVCILHRHKQRVQ .: : .: : : .. :.:: : :.. . . :.: . :.:. .: NP_001 GSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQ 340 350 360 370 380 390 220 230 240 250 260 270 pF1KE0 HIDRSNLSPRASPENRATQSILILVSTFVSSYT---LSCLFQVCMALLDNPNSLLVNTSA ..:. : ....... :: .:. . :: .... . ..:: . : NP_001 IALNDHLKQR----REVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL-LSF 400 410 420 430 440 450 280 290 300 pF1KE0 LMSVCFPTLSPFVLMSC-DP-SVY----RF--CFAWKR :. . . .. : :: .: ..: :: :: NP_001 LLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSCLKF 460 470 480 490 500 510 NP_001 KANDHGYDNFRSSNKYSSS 520 530 >>NP_001718 (OMIM: 300107) bombesin receptor subtype-3 [ (399 aa) initn: 84 init1: 63 opt: 148 Z-score: 186.3 bits: 42.9 E(85289): 0.0012 Smith-Waterman score: 148; 20.7% identity (54.9% similar) in 304 aa overlap (5-299:51-332) 10 20 30 pF1KE0 MASRYVAVGMILSQTVVGVLGSFSVLLHYLSFYC :.. ..:.: ::.::. ..:.. :. NP_001 ESSSSVVSNDNTNKGWSGDNSPGIEALCAIYITYAVIIS---VGILGN-AILIKV--FFK 30 40 50 60 70 40 50 60 70 80 90 pF1KE0 TGCRLRSTDLIVKHLIVANFLAL-RCKGVPQT-MAAFGVRYFLNALGCKLVFYLHRVGRG : .... : ...: : : : : . : : .... .:::.. ... .. : NP_001 TKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEG--WLFGRIGCKVLSFIRLTSVG 80 90 100 110 120 130 100 110 120 130 140 pF1KE0 VSIGTTCLLSVFQVITVSSRKSRWAKLKEKAPKHVGFSVLL---C-WIVCMLVNIIFPMY ::. : .:: ..: . .: :. :... ... . : ::: :. . .. NP_001 VSVFTLTILS-------ADRYKAVVKPLERQPSNAILKTCVKAGCVWIVSMIFALPEAIF 140 150 160 170 180 150 160 170 180 190 200 pF1KE0 VTGKWNYTNITVNEDLGYCSGGG-NNKIAQTLRAML--LSFPDVLCLGLMLWVSSSMVCI .. ... . . : . :.. ..:. : ....: : : .. :... : .. NP_001 -SNVYTFRDPNKNMTFESCTSYPVSKKLLQEIHSLLCFLVFY-IIPLSIISVYYSLIART 190 200 210 220 230 240 210 220 230 240 250 260 pF1KE0 LHRHKQRVQHIDRSNLSPRASPENRATQSILILVSTFVSSYTLSCLFQVCMALLDNPNSL :.. . ..:. . ..: ....:.::. :. . . :. . .. .. NP_001 LYKSTLNIPTEEQSHARKQIESRKRIARTVLVLVALFALCWLPNHLLYLYHSFT---SQT 250 260 270 280 290 300 270 280 290 300 pF1KE0 LVNTSALMSVCFPTLSPFVLMSCDPSVYRFCFAWKR :. ::. . : .: :: . : : . : NP_001 YVDPSAMHFI-FTIFSR-VLAFSNSCVNPFALYWLSKSFQKHFKAQLFCCKAERPEPPVA 310 320 330 340 350 NP_001 DTSLTTLAVMGTVPGTGSIQMSEISVTSFTGCSVKQAEDRF 360 370 380 390 >>NP_795364 (OMIM: 613965) taste receptor type 2 member (307 aa) initn: 83 init1: 83 opt: 140 Z-score: 178.3 bits: 41.1 E(85289): 0.0034 Smith-Waterman score: 140; 23.1% identity (56.9% similar) in 260 aa overlap (38-286:40-284) 10 20 30 40 50 60 pF1KE0 VGMILSQTVVGVLGSFSVLLHYLSFYCTGCRLRSTDLIVKHLIVANFLALRCKGVPQTM- :: :.:. : .. : :. :. ... NP_795 VLLFSLLSLLGIAANGFIVLVLGREWLRYGRLLPLDMILISLGASRF-CLQLVGTVHNFY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 -AAFGVRYFLNALGCKLVFYLH-RVGRGVSIGTTCLLSVFQVITVSS-RKSRWAKLKEKA .: :.: ..:: . :.:: . .... :::. . ... .: . :: . NP_795 YSAQKVEYS-GGLG-RQFFHLHWHFLNSATFWFCSWLSVLFCVKIANITHSTFLWLKWRF 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 PKHVGFSVLLCWIVCMLVNIIFPMYVTGKWNYTNITVNEDLGYCSGGGNNKIAQ----TL : : . .: .. ......: . .. : .. . . : . :..: .: NP_795 PGWVPWLLLGSVLISFIITLLF--FWVNYPVYQEFLIRKFSGNMTYKWNTRIETYYFPSL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 RAMLLSFP-DVLCLGLMLWVSSSMVCILHRHKQRVQHIDRSNLSPRASPENRATQSILIL . .. :.: .:. ...:: ..: :.:: ::.:: .: .: .. ..:: .:.. NP_795 KLVIWSIPFSVFLVSIMLLINS-----LRRHTQRMQHNGHSLQDPSTQAHTRALKSLI-- 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 VSTFVSSYTLSCLFQVCMA--LLDNPNSLLVNTSALMSVCFPTLSPFVLMSCDPSVYRFC .:. :.:: : . : ... :.. . . .:. .. ::.:. NP_795 --SFLILYALSFLSLIIDAAKFISMQNDFYWPWQIAVYLCI-SVHPFILIFSNLKLRSVF 240 250 260 270 280 290 300 pF1KE0 FAWKR NP_795 SQLLLLARGFWVA 300 301 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 03:33:44 2016 done: Sat Nov 5 03:33:45 2016 Total Scan time: 6.540 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]