FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0903, 168 aa 1>>>pF1KE0903 168 - 168 aa - 168 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6692+/-0.000961; mu= 0.0191+/- 0.055 mean_var=228.1245+/-53.155, 0's: 0 Z-trim(109.7): 174 B-trim: 0 in 0/51 Lambda= 0.084916 statistics sampled from 10872 (11067) to 10872 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.73), E-opt: 0.2 (0.34), width: 16 Scan time: 1.700 The best scores are: opt bits E(32554) CCDS75774.1 STK3 gene_id:6788|Hs108|chr8 ( 380) 766 106.6 1.7e-23 CCDS47900.1 STK3 gene_id:6788|Hs108|chr8 ( 491) 764 106.5 2.4e-23 CCDS59108.1 STK3 gene_id:6788|Hs108|chr8 ( 519) 703 99.0 4.3e-21 CCDS13341.1 STK4 gene_id:6789|Hs108|chr20 ( 487) 687 97.1 1.6e-20 >>CCDS75774.1 STK3 gene_id:6788|Hs108|chr8 (380 aa) initn: 803 init1: 765 opt: 766 Z-score: 535.4 bits: 106.6 E(32554): 1.7e-23 Smith-Waterman score: 766; 96.0% identity (97.6% similar) in 124 aa overlap (1-123:1-124) 10 20 30 40 50 60 pF1KE0 MEQPPAPKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 MEQPPAPKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPV 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 ESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTG-F :::::::::::::::::::::::::::::::::::::::::::::::::::::::::. : CCDS75 ESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTAIF 70 80 90 100 110 120 120 130 140 150 160 pF1KE0 LTDTTEGSASCDLRMDLTLFHLGAEFLHYLLLYEADPLSCVFSLLVFSV . : CCDS75 MIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIKNAKPVSILRDLI 130 140 150 160 170 180 >>CCDS47900.1 STK3 gene_id:6788|Hs108|chr8 (491 aa) initn: 764 init1: 764 opt: 764 Z-score: 532.8 bits: 106.5 E(32554): 2.4e-23 Smith-Waterman score: 770; 83.2% identity (86.6% similar) in 149 aa overlap (1-149:1-140) 10 20 30 40 50 60 pF1KE0 MEQPPAPKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MEQPPAPKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTGFL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 ESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKT--- 70 80 90 100 110 130 140 150 160 pF1KE0 TDTTEGSASCDLRMDLTLFHLGAEFLHYLLLYEADPLSCVFSLLVFSV : . :. : : :.::.. CCDS47 --LIEDEIATILKSTLK----GLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQL 120 130 140 150 160 170 >>CCDS59108.1 STK3 gene_id:6788|Hs108|chr8 (519 aa) initn: 703 init1: 703 opt: 703 Z-score: 492.1 bits: 99.0 E(32554): 4.3e-21 Smith-Waterman score: 709; 82.3% identity (85.8% similar) in 141 aa overlap (9-149:37-168) 10 20 30 pF1KE0 MEQPPAPKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSY :::::::::::::::::::::::::::::: CCDS59 SGITICLRNGAASVFKKKEWSTQGEENKQDSKLKKLSEDSLTKQPEEVFDVLEKLGEGSY 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 GSVFKAIHKESGQVVAIKQVPVESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 GSVFKAIHKESGQVVAIKQVPVESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIV 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 MEYCGAGSVSDIIRLRNKTGFLTDTTEGSASCDLRMDLTLFHLGAEFLHYLLLYEADPLS ::::::::::::::::::: : . :. : : :.::.. CCDS59 MEYCGAGSVSDIIRLRNKT-----LIEDEIATILKSTLK----GLEYLHFMRKIHRDIKA 130 140 150 160 170 160 pF1KE0 CVFSLLVFSV CCDS59 GNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGI 180 190 200 210 220 230 >>CCDS13341.1 STK4 gene_id:6789|Hs108|chr20 (487 aa) initn: 687 init1: 687 opt: 687 Z-score: 481.8 bits: 97.1 E(32554): 1.6e-20 Smith-Waterman score: 697; 77.6% identity (86.0% similar) in 143 aa overlap (7-149:10-143) 10 20 30 40 50 pF1KE0 MEQPPAPKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQ :. .::::.::::::::::::::::::::::::::.::::::.::.::::: CCDS13 METVQLRNPPRRQLKKLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 VPVESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKT :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: CCDS13 VPVESDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKT 70 80 90 100 110 120 120 130 140 150 160 pF1KE0 GFLTDTTEGSASCDLRMDLTLFHLGAEFLHYLLLYEADPLSCVFSLLVFSV :: . :. : : :.::.. CCDS13 -----LTEDEIATILQSTLK----GLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVA 130 140 150 160 170 CCDS13 GQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMR 180 190 200 210 220 230 168 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:25:09 2016 done: Sat Nov 5 04:25:09 2016 Total Scan time: 1.700 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]