FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0909, 225 aa 1>>>pF1KE0909 225 - 225 aa - 225 aa Library: /omim/omim.rfq.tfa 64369986 residues in 92320 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9231+/-0.000263; mu= 11.0212+/- 0.016 mean_var=75.0562+/-15.260, 0's: 0 Z-trim(119.5): 15 B-trim: 187 in 1/53 Lambda= 0.148041 statistics sampled from 35018 (35033) to 35018 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.762), E-opt: 0.2 (0.379), width: 16 Scan time: 3.580 The best scores are: opt bits E(92320) NP_001167 (OMIM: 602844) rho GDP-dissociation inhi ( 225) 1518 332.9 2.9e-91 NP_001172006 (OMIM: 601925,615244) rho GDP-dissoci ( 204) 793 178.0 1.1e-44 NP_004300 (OMIM: 601925,615244) rho GDP-dissociati ( 204) 793 178.0 1.1e-44 NP_001308351 (OMIM: 602843) rho GDP-dissociation i ( 201) 763 171.6 9.3e-43 NP_001308349 (OMIM: 602843) rho GDP-dissociation i ( 201) 763 171.6 9.3e-43 XP_024304747 (OMIM: 602843) rho GDP-dissociation i ( 201) 763 171.6 9.3e-43 NP_001308350 (OMIM: 602843) rho GDP-dissociation i ( 201) 763 171.6 9.3e-43 NP_001166 (OMIM: 602843) rho GDP-dissociation inhi ( 201) 763 171.6 9.3e-43 NP_001308352 (OMIM: 602843) rho GDP-dissociation i ( 201) 763 171.6 9.3e-43 NP_001288170 (OMIM: 601925,615244) rho GDP-dissoci ( 235) 625 142.1 7.9e-34 NP_001288169 (OMIM: 601925,615244) rho GDP-dissoci ( 235) 625 142.1 7.9e-34 NP_001288172 (OMIM: 601925,615244) rho GDP-dissoci ( 249) 563 128.9 8.1e-30 XP_011521876 (OMIM: 601925,615244) rho GDP-dissoci ( 249) 563 128.9 8.1e-30 NP_001288171 (OMIM: 601925,615244) rho GDP-dissoci ( 337) 491 113.6 4.5e-25 NP_001172007 (OMIM: 601925,615244) rho GDP-dissoci ( 160) 456 106.0 4.1e-23 >>NP_001167 (OMIM: 602844) rho GDP-dissociation inhibito (225 aa) initn: 1518 init1: 1518 opt: 1518 Z-score: 1760.0 bits: 332.9 E(92320): 2.9e-91 Smith-Waterman score: 1518; 100.0% identity (100.0% similar) in 225 aa overlap (1-225:1-225) 10 20 30 40 50 60 pF1KE0 MLGLDACELGAQLLELLRLALCARVLLADKEGGPPAVDEVLDEAVPEYRAPGRKSLLEIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLGLDACELGAQLLELLRLALCARVLLADKEGGPPAVDEVLDEAVPEYRAPGRKSLLEIR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 QLDPDDRSLAKYKRVLLGPLPPAVDPSLPNVQVTRLTLLSEQAPGPVVMDLTGDLAVLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLDPDDRSLAKYKRVLLGPLPPAVDPSLPNVQVTRLTLLSEQAPGPVVMDLTGDLAVLKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 QVFVLKEGVDYRVKISFKVHREIVSGLKCLHHTYRRGLRVDKTVYMVGSYGPSAQEYEFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVFVLKEGVDYRVKISFKVHREIVSGLKCLHHTYRRGLRVDKTVYMVGSYGPSAQEYEFV 130 140 150 160 170 180 190 200 210 220 pF1KE0 TPVEEAPRGALVRGPYLVVSLFTDDDRTHHLSWEWGLCICQDWKD ::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPVEEAPRGALVRGPYLVVSLFTDDDRTHHLSWEWGLCICQDWKD 190 200 210 220 >>NP_001172006 (OMIM: 601925,615244) rho GDP-dissociatio (204 aa) initn: 792 init1: 792 opt: 793 Z-score: 923.8 bits: 178.0 E(92320): 1.1e-44 Smith-Waterman score: 793; 61.1% identity (83.2% similar) in 190 aa overlap (36-225:15-204) 10 20 30 40 50 60 pF1KE0 ACELGAQLLELLRLALCARVLLADKEGGPPAVDEVLDEAVPEYRAPGRKSLLEIRQLDPD :... :: .:. :..::. ::..:: : NP_001 MAEQEPTAEQLAQIAAENEEDEHSVNYKPPAQKSIQEIQELDKD 10 20 30 40 70 80 90 100 110 120 pF1KE0 DRSLAKYKRVLLGPLPPAVDPSLPNVQVTRLTLLSEQAPGPVVMDLTGDLAVLKDQVFVL :.:: :::..::: . ..::..::: :: :::. .::::. .:::::: .: : ::: NP_001 DESLRKYKEALLGRVAVSADPNVPNVVVTGLTLVCSSAPGPLELDLTGDLESFKKQSFVL 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 KEGVDYRVKISFKVHREIVSGLKCLHHTYRRGLRVDKTVYMVGSYGPSAQEYEFVTPVEE ::::.::.::::.:.::::::.: ..::::.:...::: :::::::: :.::::.::::: NP_001 KEGVEYRIKISFRVNREIVSGMKYIQHTYRKGVKIDKTDYMVGSYGPRAEEYEFLTPVEE 110 120 130 140 150 160 190 200 210 220 pF1KE0 APRGALVRGPYLVVSLFTDDDRTHHLSWEWGLCICQDWKD ::.: :.:: : . : :::::.: ::::::.: : .:::: NP_001 APKGMLARGSYSIKSRFTDDDKTDHLSWEWNLTIKKDWKD 170 180 190 200 >>NP_004300 (OMIM: 601925,615244) rho GDP-dissociation i (204 aa) initn: 792 init1: 792 opt: 793 Z-score: 923.8 bits: 178.0 E(92320): 1.1e-44 Smith-Waterman score: 793; 61.1% identity (83.2% similar) in 190 aa overlap (36-225:15-204) 10 20 30 40 50 60 pF1KE0 ACELGAQLLELLRLALCARVLLADKEGGPPAVDEVLDEAVPEYRAPGRKSLLEIRQLDPD :... :: .:. :..::. ::..:: : NP_004 MAEQEPTAEQLAQIAAENEEDEHSVNYKPPAQKSIQEIQELDKD 10 20 30 40 70 80 90 100 110 120 pF1KE0 DRSLAKYKRVLLGPLPPAVDPSLPNVQVTRLTLLSEQAPGPVVMDLTGDLAVLKDQVFVL :.:: :::..::: . ..::..::: :: :::. .::::. .:::::: .: : ::: NP_004 DESLRKYKEALLGRVAVSADPNVPNVVVTGLTLVCSSAPGPLELDLTGDLESFKKQSFVL 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 KEGVDYRVKISFKVHREIVSGLKCLHHTYRRGLRVDKTVYMVGSYGPSAQEYEFVTPVEE ::::.::.::::.:.::::::.: ..::::.:...::: :::::::: :.::::.::::: NP_004 KEGVEYRIKISFRVNREIVSGMKYIQHTYRKGVKIDKTDYMVGSYGPRAEEYEFLTPVEE 110 120 130 140 150 160 190 200 210 220 pF1KE0 APRGALVRGPYLVVSLFTDDDRTHHLSWEWGLCICQDWKD ::.: :.:: : . : :::::.: ::::::.: : .:::: NP_004 APKGMLARGSYSIKSRFTDDDKTDHLSWEWNLTIKKDWKD 170 180 190 200 >>NP_001308351 (OMIM: 602843) rho GDP-dissociation inhib (201 aa) initn: 757 init1: 736 opt: 763 Z-score: 889.3 bits: 171.6 E(92320): 9.3e-43 Smith-Waterman score: 763; 57.8% identity (80.4% similar) in 199 aa overlap (31-225:3-201) 10 20 30 40 50 pF1KE0 MLGLDACELGAQLLELLRLALCARVLLADKEGGP-PAVDEVLDEAVP---EYRAPGRKSL : .: : :.: :. . .:. : .::: NP_001 MTEKAPEPHVEEDDDDELDSKLNYKPPPQKSL 10 20 30 60 70 80 90 100 110 pF1KE0 LEIRQLDPDDRSLAKYKRVLLGPLPPAVDPSLPNVQVTRLTLLSEQAPGPVVMDLTGDLA :....: ::.:: :::..::: : ..::. ::: ::::::. :.::::..::::::: NP_001 KELQEMDKDDESLIKYKKTLLGDGPVVTDPKAPNVVVTRLTLVCESAPGPITMDLTGDLE 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 VLKDQVFVLKEGVDYRVKISFKVHREIVSGLKCLHHTYRRGLRVDKTVYMVGSYGPSAQE .:: ...::::: .::::: :::.:.:::::: ..:::: :..:::...::::::: .: NP_001 ALKKETIVLKEGSEYRVKIHFKVNRDIVSGLKYVQHTYRTGVKVDKATFMVGSYGPRPEE 100 110 120 130 140 150 180 190 200 210 220 pF1KE0 YEFVTPVEEAPRGALVRGPYLVVSLFTDDDRTHHLSWEWGLCICQDWKD :::.:::::::.: :.:: : :.:::::. ::::::.: : ..: . NP_001 YEFLTPVEEAPKGMLARGTYHNKSFFTDDDKQDHLSWEWNLSIKKEWTE 160 170 180 190 200 >>NP_001308349 (OMIM: 602843) rho GDP-dissociation inhib (201 aa) initn: 757 init1: 736 opt: 763 Z-score: 889.3 bits: 171.6 E(92320): 9.3e-43 Smith-Waterman score: 763; 57.8% identity (80.4% similar) in 199 aa overlap (31-225:3-201) 10 20 30 40 50 pF1KE0 MLGLDACELGAQLLELLRLALCARVLLADKEGGP-PAVDEVLDEAVP---EYRAPGRKSL : .: : :.: :. . .:. : .::: NP_001 MTEKAPEPHVEEDDDDELDSKLNYKPPPQKSL 10 20 30 60 70 80 90 100 110 pF1KE0 LEIRQLDPDDRSLAKYKRVLLGPLPPAVDPSLPNVQVTRLTLLSEQAPGPVVMDLTGDLA :....: ::.:: :::..::: : ..::. ::: ::::::. :.::::..::::::: NP_001 KELQEMDKDDESLIKYKKTLLGDGPVVTDPKAPNVVVTRLTLVCESAPGPITMDLTGDLE 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 VLKDQVFVLKEGVDYRVKISFKVHREIVSGLKCLHHTYRRGLRVDKTVYMVGSYGPSAQE .:: ...::::: .::::: :::.:.:::::: ..:::: :..:::...::::::: .: NP_001 ALKKETIVLKEGSEYRVKIHFKVNRDIVSGLKYVQHTYRTGVKVDKATFMVGSYGPRPEE 100 110 120 130 140 150 180 190 200 210 220 pF1KE0 YEFVTPVEEAPRGALVRGPYLVVSLFTDDDRTHHLSWEWGLCICQDWKD :::.:::::::.: :.:: : :.:::::. ::::::.: : ..: . NP_001 YEFLTPVEEAPKGMLARGTYHNKSFFTDDDKQDHLSWEWNLSIKKEWTE 160 170 180 190 200 >>XP_024304747 (OMIM: 602843) rho GDP-dissociation inhib (201 aa) initn: 757 init1: 736 opt: 763 Z-score: 889.3 bits: 171.6 E(92320): 9.3e-43 Smith-Waterman score: 763; 57.8% identity (80.4% similar) in 199 aa overlap (31-225:3-201) 10 20 30 40 50 pF1KE0 MLGLDACELGAQLLELLRLALCARVLLADKEGGP-PAVDEVLDEAVP---EYRAPGRKSL : .: : :.: :. . .:. : .::: XP_024 MTEKAPEPHVEEDDDDELDSKLNYKPPPQKSL 10 20 30 60 70 80 90 100 110 pF1KE0 LEIRQLDPDDRSLAKYKRVLLGPLPPAVDPSLPNVQVTRLTLLSEQAPGPVVMDLTGDLA :....: ::.:: :::..::: : ..::. ::: ::::::. :.::::..::::::: XP_024 KELQEMDKDDESLIKYKKTLLGDGPVVTDPKAPNVVVTRLTLVCESAPGPITMDLTGDLE 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 VLKDQVFVLKEGVDYRVKISFKVHREIVSGLKCLHHTYRRGLRVDKTVYMVGSYGPSAQE .:: ...::::: .::::: :::.:.:::::: ..:::: :..:::...::::::: .: XP_024 ALKKETIVLKEGSEYRVKIHFKVNRDIVSGLKYVQHTYRTGVKVDKATFMVGSYGPRPEE 100 110 120 130 140 150 180 190 200 210 220 pF1KE0 YEFVTPVEEAPRGALVRGPYLVVSLFTDDDRTHHLSWEWGLCICQDWKD :::.:::::::.: :.:: : :.:::::. ::::::.: : ..: . XP_024 YEFLTPVEEAPKGMLARGTYHNKSFFTDDDKQDHLSWEWNLSIKKEWTE 160 170 180 190 200 >>NP_001308350 (OMIM: 602843) rho GDP-dissociation inhib (201 aa) initn: 757 init1: 736 opt: 763 Z-score: 889.3 bits: 171.6 E(92320): 9.3e-43 Smith-Waterman score: 763; 57.8% identity (80.4% similar) in 199 aa overlap (31-225:3-201) 10 20 30 40 50 pF1KE0 MLGLDACELGAQLLELLRLALCARVLLADKEGGP-PAVDEVLDEAVP---EYRAPGRKSL : .: : :.: :. . .:. : .::: NP_001 MTEKAPEPHVEEDDDDELDSKLNYKPPPQKSL 10 20 30 60 70 80 90 100 110 pF1KE0 LEIRQLDPDDRSLAKYKRVLLGPLPPAVDPSLPNVQVTRLTLLSEQAPGPVVMDLTGDLA :....: ::.:: :::..::: : ..::. ::: ::::::. :.::::..::::::: NP_001 KELQEMDKDDESLIKYKKTLLGDGPVVTDPKAPNVVVTRLTLVCESAPGPITMDLTGDLE 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 VLKDQVFVLKEGVDYRVKISFKVHREIVSGLKCLHHTYRRGLRVDKTVYMVGSYGPSAQE .:: ...::::: .::::: :::.:.:::::: ..:::: :..:::...::::::: .: NP_001 ALKKETIVLKEGSEYRVKIHFKVNRDIVSGLKYVQHTYRTGVKVDKATFMVGSYGPRPEE 100 110 120 130 140 150 180 190 200 210 220 pF1KE0 YEFVTPVEEAPRGALVRGPYLVVSLFTDDDRTHHLSWEWGLCICQDWKD :::.:::::::.: :.:: : :.:::::. ::::::.: : ..: . NP_001 YEFLTPVEEAPKGMLARGTYHNKSFFTDDDKQDHLSWEWNLSIKKEWTE 160 170 180 190 200 >>NP_001166 (OMIM: 602843) rho GDP-dissociation inhibito (201 aa) initn: 757 init1: 736 opt: 763 Z-score: 889.3 bits: 171.6 E(92320): 9.3e-43 Smith-Waterman score: 763; 57.8% identity (80.4% similar) in 199 aa overlap (31-225:3-201) 10 20 30 40 50 pF1KE0 MLGLDACELGAQLLELLRLALCARVLLADKEGGP-PAVDEVLDEAVP---EYRAPGRKSL : .: : :.: :. . .:. : .::: NP_001 MTEKAPEPHVEEDDDDELDSKLNYKPPPQKSL 10 20 30 60 70 80 90 100 110 pF1KE0 LEIRQLDPDDRSLAKYKRVLLGPLPPAVDPSLPNVQVTRLTLLSEQAPGPVVMDLTGDLA :....: ::.:: :::..::: : ..::. ::: ::::::. :.::::..::::::: NP_001 KELQEMDKDDESLIKYKKTLLGDGPVVTDPKAPNVVVTRLTLVCESAPGPITMDLTGDLE 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 VLKDQVFVLKEGVDYRVKISFKVHREIVSGLKCLHHTYRRGLRVDKTVYMVGSYGPSAQE .:: ...::::: .::::: :::.:.:::::: ..:::: :..:::...::::::: .: NP_001 ALKKETIVLKEGSEYRVKIHFKVNRDIVSGLKYVQHTYRTGVKVDKATFMVGSYGPRPEE 100 110 120 130 140 150 180 190 200 210 220 pF1KE0 YEFVTPVEEAPRGALVRGPYLVVSLFTDDDRTHHLSWEWGLCICQDWKD :::.:::::::.: :.:: : :.:::::. ::::::.: : ..: . NP_001 YEFLTPVEEAPKGMLARGTYHNKSFFTDDDKQDHLSWEWNLSIKKEWTE 160 170 180 190 200 >>NP_001308352 (OMIM: 602843) rho GDP-dissociation inhib (201 aa) initn: 757 init1: 736 opt: 763 Z-score: 889.3 bits: 171.6 E(92320): 9.3e-43 Smith-Waterman score: 763; 57.8% identity (80.4% similar) in 199 aa overlap (31-225:3-201) 10 20 30 40 50 pF1KE0 MLGLDACELGAQLLELLRLALCARVLLADKEGGP-PAVDEVLDEAVP---EYRAPGRKSL : .: : :.: :. . .:. : .::: NP_001 MTEKAPEPHVEEDDDDELDSKLNYKPPPQKSL 10 20 30 60 70 80 90 100 110 pF1KE0 LEIRQLDPDDRSLAKYKRVLLGPLPPAVDPSLPNVQVTRLTLLSEQAPGPVVMDLTGDLA :....: ::.:: :::..::: : ..::. ::: ::::::. :.::::..::::::: NP_001 KELQEMDKDDESLIKYKKTLLGDGPVVTDPKAPNVVVTRLTLVCESAPGPITMDLTGDLE 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 VLKDQVFVLKEGVDYRVKISFKVHREIVSGLKCLHHTYRRGLRVDKTVYMVGSYGPSAQE .:: ...::::: .::::: :::.:.:::::: ..:::: :..:::...::::::: .: NP_001 ALKKETIVLKEGSEYRVKIHFKVNRDIVSGLKYVQHTYRTGVKVDKATFMVGSYGPRPEE 100 110 120 130 140 150 180 190 200 210 220 pF1KE0 YEFVTPVEEAPRGALVRGPYLVVSLFTDDDRTHHLSWEWGLCICQDWKD :::.:::::::.: :.:: : :.:::::. ::::::.: : ..: . NP_001 YEFLTPVEEAPKGMLARGTYHNKSFFTDDDKQDHLSWEWNLSIKKEWTE 160 170 180 190 200 >>NP_001288170 (OMIM: 601925,615244) rho GDP-dissociatio (235 aa) initn: 624 init1: 624 opt: 625 Z-score: 728.9 bits: 142.1 E(92320): 7.9e-34 Smith-Waterman score: 625; 59.6% identity (84.6% similar) in 156 aa overlap (36-191:15-170) 10 20 30 40 50 60 pF1KE0 ACELGAQLLELLRLALCARVLLADKEGGPPAVDEVLDEAVPEYRAPGRKSLLEIRQLDPD :... :: .:. :..::. ::..:: : NP_001 MAEQEPTAEQLAQIAAENEEDEHSVNYKPPAQKSIQEIQELDKD 10 20 30 40 70 80 90 100 110 120 pF1KE0 DRSLAKYKRVLLGPLPPAVDPSLPNVQVTRLTLLSEQAPGPVVMDLTGDLAVLKDQVFVL :.:: :::..::: . ..::..::: :: :::. .::::. .:::::: .: : ::: NP_001 DESLRKYKEALLGRVAVSADPNVPNVVVTGLTLVCSSAPGPLELDLTGDLESFKKQSFVL 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 KEGVDYRVKISFKVHREIVSGLKCLHHTYRRGLRVDKTVYMVGSYGPSAQEYEFVTPVEE ::::.::.::::.:.::::::.: ..::::.:...::: :::::::: :.::::.::::: NP_001 KEGVEYRIKISFRVNREIVSGMKYIQHTYRKGVKIDKTDYMVGSYGPRAEEYEFLTPVEE 110 120 130 140 150 160 190 200 210 220 pF1KE0 APRGALVRGPYLVVSLFTDDDRTHHLSWEWGLCICQDWKD ::.:.. NP_001 APKGSISPSHPRPGFRRERSSHSPGPVVAPGRVRLLLRGGAGVWDARPRGGRAVLQPRCS 170 180 190 200 210 220 225 residues in 1 query sequences 64369986 residues in 92320 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Oct 24 21:45:55 2019 done: Thu Oct 24 21:45:56 2019 Total Scan time: 3.580 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]