FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0910, 231 aa 1>>>pF1KE0910 231 - 231 aa - 231 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3303+/-0.00086; mu= 13.3362+/- 0.051 mean_var=56.6259+/-11.715, 0's: 0 Z-trim(105.3): 24 B-trim: 369 in 1/51 Lambda= 0.170438 statistics sampled from 8339 (8347) to 8339 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.643), E-opt: 0.2 (0.256), width: 16 Scan time: 1.730 The best scores are: opt bits E(32554) CCDS4481.1 NQO2 gene_id:4835|Hs108|chr6 ( 231) 1569 393.9 4.6e-110 CCDS10883.1 NQO1 gene_id:1728|Hs108|chr16 ( 274) 743 190.8 7.5e-49 CCDS75388.1 NQO2 gene_id:4835|Hs108|chr6 ( 193) 657 169.6 1.3e-42 CCDS32472.1 NQO1 gene_id:1728|Hs108|chr16 ( 240) 463 121.9 3.5e-28 CCDS32471.1 NQO1 gene_id:1728|Hs108|chr16 ( 236) 315 85.5 3.1e-17 CCDS67067.1 NQO1 gene_id:1728|Hs108|chr16 ( 202) 314 85.3 3.2e-17 >>CCDS4481.1 NQO2 gene_id:4835|Hs108|chr6 (231 aa) initn: 1569 init1: 1569 opt: 1569 Z-score: 2089.4 bits: 393.9 E(32554): 4.6e-110 Smith-Waterman score: 1569; 99.6% identity (100.0% similar) in 231 aa overlap (1-231:1-231) 10 20 30 40 50 60 pF1KE0 MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTL ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: CCDS44 MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 SNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFC 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 GFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ 190 200 210 220 230 >>CCDS10883.1 NQO1 gene_id:1728|Hs108|chr16 (274 aa) initn: 747 init1: 722 opt: 743 Z-score: 990.5 bits: 190.8 E(32554): 7.5e-49 Smith-Waterman score: 743; 48.9% identity (76.5% similar) in 221 aa overlap (1-221:1-221) 10 20 30 40 50 60 pF1KE0 MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTL :.:...::: ::.: ::: ..:..:. :...: :. ::::::::.: . ::::: : CCDS10 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRV ..: :.: .:. :::. :. ::. ::::.. :::::::::: ::.::::::::..:: CCDS10 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFC . ::. ..::.: ...: :.::.::::.. ::. :..:: .:::.: : :::: CCDS10 FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 GFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ ::.:: ::.... . . : .. .:..::..:: : :. CCDS10 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK 190 200 210 220 230 240 CCDS10 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK 250 260 270 >>CCDS75388.1 NQO2 gene_id:4835|Hs108|chr6 (193 aa) initn: 656 init1: 656 opt: 657 Z-score: 878.7 bits: 169.6 E(32554): 1.3e-42 Smith-Waterman score: 1199; 83.1% identity (83.5% similar) in 231 aa overlap (1-231:1-193) 10 20 30 40 50 60 pF1KE0 MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTL ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: CCDS75 MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRV ::::::::::::::::::::::::::::::::::::::::: CCDS75 SNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQ------------------- 70 80 90 100 130 140 150 160 170 180 pF1KE0 LCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFC ::::::::::::::::::::::::::::::::::::::::: CCDS75 -------------------GKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFC 110 120 130 140 190 200 210 220 230 pF1KE0 GFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 GFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ 150 160 170 180 190 >>CCDS32472.1 NQO1 gene_id:1728|Hs108|chr16 (240 aa) initn: 577 init1: 442 opt: 463 Z-score: 619.3 bits: 121.9 E(32554): 3.5e-28 Smith-Waterman score: 552; 41.6% identity (64.7% similar) in 221 aa overlap (1-221:1-187) 10 20 30 40 50 60 pF1KE0 MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTL :.:...::: ::.: ::: ..:..:. :...: :. ::::::::.: . ::::: : CCDS32 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRV ..: :.: .:. :::. :. ::. ::::.. :::::::::: ::.::::::::..:: CCDS32 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFC . ::. ..::.: :.. : :::: CCDS32 FIGEFAYTYAAMYDKG----------------------------------PFRSGILHFC 130 140 190 200 210 220 230 pF1KE0 GFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ ::.:: ::.... . . : .. .:..::..:: : :. CCDS32 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK 150 160 170 180 190 200 CCDS32 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK 210 220 230 240 >>CCDS32471.1 NQO1 gene_id:1728|Hs108|chr16 (236 aa) initn: 597 init1: 313 opt: 315 Z-score: 422.8 bits: 85.5 E(32554): 3.1e-17 Smith-Waterman score: 509; 39.8% identity (62.9% similar) in 221 aa overlap (1-221:1-183) 10 20 30 40 50 60 pF1KE0 MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTL :.:...::: ::.: ::: ..:..:. :...: :. ::::::::.: . ::::: : CCDS32 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRV ..: :.: .:. :::. :. ::. ::::.. ::::::: CCDS32 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQ------------------- 70 80 90 100 130 140 150 160 170 180 pF1KE0 LCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFC .: :.::.::::.. ::. :..:: .:::.: : :::: CCDS32 -------------------SKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC 110 120 130 140 190 200 210 220 230 pF1KE0 GFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ ::.:: ::.... . . : .. .:..::..:: : :. CCDS32 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK 150 160 170 180 190 200 CCDS32 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK 210 220 230 >>CCDS67067.1 NQO1 gene_id:1728|Hs108|chr16 (202 aa) initn: 474 init1: 314 opt: 314 Z-score: 422.6 bits: 85.3 E(32554): 3.2e-17 Smith-Waterman score: 314; 49.5% identity (74.8% similar) in 107 aa overlap (1-107:1-107) 10 20 30 40 50 60 pF1KE0 MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTL :.:...::: ::.: ::: ..:..:. :...: :. ::::::::.: . ::::: : CCDS67 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRV ..: :.: .:. :::. :. ::. ::::.. ::::::: . : CCDS67 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQSGILHFCGFQVLEPQLTYS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFC CCDS67 IGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMKKEVQDEEKNKKF 130 140 150 160 170 180 231 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:27:30 2016 done: Sat Nov 5 04:27:30 2016 Total Scan time: 1.730 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]