FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0911, 239 aa 1>>>pF1KE0911 239 - 239 aa - 239 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3710+/-0.000796; mu= 13.1936+/- 0.047 mean_var=56.4887+/-11.453, 0's: 0 Z-trim(106.6): 14 B-trim: 503 in 1/49 Lambda= 0.170645 statistics sampled from 9070 (9078) to 9070 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.279), width: 16 Scan time: 2.030 The best scores are: opt bits E(32554) CCDS9646.1 EGLN3 gene_id:112399|Hs108|chr14 ( 239) 1663 417.4 4.2e-117 CCDS1595.1 EGLN1 gene_id:54583|Hs108|chr1 ( 426) 1043 264.8 6.3e-71 CCDS12567.1 EGLN2 gene_id:112398|Hs108|chr19 ( 407) 1002 254.7 6.6e-68 CCDS76671.1 EGLN3 gene_id:112399|Hs108|chr14 ( 145) 850 217.2 4.7e-57 >>CCDS9646.1 EGLN3 gene_id:112399|Hs108|chr14 (239 aa) initn: 1663 init1: 1663 opt: 1663 Z-score: 2215.9 bits: 417.4 E(32554): 4.2e-117 Smith-Waterman score: 1663; 100.0% identity (100.0% similar) in 239 aa overlap (1-239:1-239) 10 20 30 40 50 60 pF1KE0 MPLGHIMRLDLEKIALEYIVPCLHEVGFCYLDNFLGEVVGDCVLERVKQLHCTGALRDGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 MPLGHIMRLDLEKIALEYIVPCLHEVGFCYLDNFLGEVVGDCVLERVKQLHCTGALRDGQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 LAGPRAGVSKRHLRGDQITWIGGNEEGCEAISFLLSLIDRLVLYCGSRLGKYYVKERSKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 LAGPRAGVSKRHLRGDQITWIGGNEEGCEAISFLLSLIDRLVLYCGSRLGKYYVKERSKA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 MVACYPGNGTGYVRHVDNPNGDGRCITCIYYLNKNWDAKLHGGILRIFPEGKSFIADVEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 MVACYPGNGTGYVRHVDNPNGDGRCITCIYYLNKNWDAKLHGGILRIFPEGKSFIADVEP 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 IFDRLLFFWSDRRNPHEVQPSYATRYAMTVWYFDAEERAEAKKKFRNLTRKTESALTED ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 IFDRLLFFWSDRRNPHEVQPSYATRYAMTVWYFDAEERAEAKKKFRNLTRKTESALTED 190 200 210 220 230 >>CCDS1595.1 EGLN1 gene_id:54583|Hs108|chr1 (426 aa) initn: 1032 init1: 854 opt: 1043 Z-score: 1386.9 bits: 264.8 E(32554): 6.3e-71 Smith-Waterman score: 1043; 64.3% identity (85.7% similar) in 224 aa overlap (2-225:181-403) 10 20 30 pF1KE0 MPLGHIMRLDLEKIALEYIVPCLHEVGFCYL : :. : :.::::::::... :.: . CCDS15 ARSSLFQEKANLYPPSNTPGDALSPGGGLRPNGQTKPLPALKLALEYIVPCMNKHGICVV 160 170 180 190 200 210 40 50 60 70 80 90 pF1KE0 DNFLGEVVGDCVLERVKQLHCTGALRDGQLAGPRAGVSKRHLRGDQITWIGGNEEGCEAI :.:::. .:. . ..:. :: :: . ::::.. .. :: .:::.:::: :.: :::.: CCDS15 DDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSK-DIRGDKITWIEGKEPGCETI 220 230 240 250 260 100 110 120 130 140 150 pF1KE0 SFLLSLIDRLVLYCGSRLGKYYVKERSKAMVACYPGNGTGYVRHVDNPNGDGRCITCIYY ..:.: .: :. .:...::.: .. :.:::::::::::::::::::::::::::.::::: CCDS15 GLLMSSMDDLIRHCNGKLGSYKINGRTKAMVACYPGNGTGYVRHVDNPNGDGRCVTCIYY 270 280 290 300 310 320 160 170 180 190 200 210 pF1KE0 LNKNWDAKLHGGILRIFPEGKSFIADVEPIFDRLLFFWSDRRNPHEVQPSYATRYAMTVW :::.::::. :::::::::::. .::.:: :::::::::::::::::::.::::::.::: CCDS15 LNKDWDAKVSGGILRIFPEGKAQFADIEPKFDRLLFFWSDRRNPHEVQPAYATRYAITVW 330 340 350 360 370 380 220 230 pF1KE0 YFDAEERAEAKKKFRNLTRKTESALTED ::::.:::.:: :. CCDS15 YFDADERARAKVKYLTGEKGVRVELNKPSDSVGKDVF 390 400 410 420 >>CCDS12567.1 EGLN2 gene_id:112398|Hs108|chr19 (407 aa) initn: 1025 init1: 820 opt: 1002 Z-score: 1332.6 bits: 254.7 E(32554): 6.6e-68 Smith-Waterman score: 1002; 61.9% identity (86.0% similar) in 215 aa overlap (12-226:175-388) 10 20 30 40 pF1KE0 MPLGHIMRLDLEKIALEYIVPCLHEVGFCYLDNFLGEVVGD :..::.:::::.. :.: :.::: ..: CCDS12 EREGGMSCSCSSGSGEASAGLMEEALPSAPERLALDYIVPCMRYYGICVKDSFLGAALGG 150 160 170 180 190 200 50 60 70 80 90 100 pF1KE0 CVLERVKQLHCTGALRDGQLAGPRAGVSKRHLRGDQITWIGGNEEGCEAISFLLSLIDRL :: .:. :. : ::::::.. :: . : .:::::.:. :.: ::..:. :.. .: . CCDS12 RVLAEVEALKRGGRLRDGQLVSQRA-IPPRSIRGDQIAWVEGHEPGCRSIGALMAHVDAV 210 220 230 240 250 260 110 120 130 140 150 160 pF1KE0 VLYCGSRLGKYYVKERSKAMVACYPGNGTGYVRHVDNPNGDGRCITCIYYLNKNWDAKLH . .:..:::.: .. :.::::::::::: :::::::::.:::::::::::::.:::.:.: CCDS12 IRHCAGRLGSYVINGRTKAMVACYPGNGLGYVRHVDNPHGDGRCITCIYYLNQNWDVKVH 270 280 290 300 310 320 170 180 190 200 210 220 pF1KE0 GGILRIFPEGKSFIADVEPIFDRLLFFWSDRRNPHEVQPSYATRYAMTVWYFDAEERAEA ::.:.:::::. .:..::.:::::.:::::::::::.:.::::::.:::::::.::: : CCDS12 GGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEVKPAYATRYAITVWYFDAKERAAA 330 340 350 360 370 380 230 pF1KE0 KKKFRNLTRKTESALTED : :.. CCDS12 KDKYQLASGQKGVQVPVSQPPTPT 390 400 >>CCDS76671.1 EGLN3 gene_id:112399|Hs108|chr14 (145 aa) initn: 845 init1: 845 opt: 850 Z-score: 1137.8 bits: 217.2 E(32554): 4.7e-57 Smith-Waterman score: 850; 94.6% identity (96.1% similar) in 129 aa overlap (111-239:17-145) 90 100 110 120 130 140 pF1KE0 IGGNEEGCEAISFLLSLIDRLVLYCGSRLGKYYVKERSKAMVACYPGNGTGYVRHVDNPN .: : .::::::::::::::::::::: CCDS76 MPLGHIMRLDLEKIALEYIVPCLHEAMVACYPGNGTGYVRHVDNPN 10 20 30 40 150 160 170 180 190 200 pF1KE0 GDGRCITCIYYLNKNWDAKLHGGILRIFPEGKSFIADVEPIFDRLLFFWSDRRNPHEVQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 GDGRCITCIYYLNKNWDAKLHGGILRIFPEGKSFIADVEPIFDRLLFFWSDRRNPHEVQP 50 60 70 80 90 100 210 220 230 pF1KE0 SYATRYAMTVWYFDAEERAEAKKKFRNLTRKTESALTED ::::::::::::::::::::::::::::::::::::::: CCDS76 SYATRYAMTVWYFDAEERAEAKKKFRNLTRKTESALTED 110 120 130 140 239 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:27:58 2016 done: Sat Nov 5 04:27:58 2016 Total Scan time: 2.030 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]