FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0913, 254 aa 1>>>pF1KE0913 254 - 254 aa - 254 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1798+/-0.000367; mu= 15.7304+/- 0.023 mean_var=81.9146+/-16.396, 0's: 0 Z-trim(113.7): 109 B-trim: 33 in 1/57 Lambda= 0.141708 statistics sampled from 23062 (23183) to 23062 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.272), width: 16 Scan time: 6.690 The best scores are: opt bits E(85289) NP_061984 (OMIM: 142860) HLA class II histocompati ( 254) 1707 358.6 6.2e-99 NP_291032 (OMIM: 142880) HLA class II histocompati ( 260) 998 213.7 2.7e-55 NP_001229453 (OMIM: 142880) HLA class II histocomp ( 260) 998 213.7 2.7e-55 NP_001229454 (OMIM: 142880) HLA class II histocomp ( 260) 998 213.7 2.7e-55 NP_002110 (OMIM: 142930) HLA class II histocompati ( 250) 943 202.4 6.4e-52 NP_002113 (OMIM: 146880,212750) HLA class II histo ( 255) 929 199.5 4.7e-51 NP_064440 (OMIM: 613503) HLA class II histocompati ( 255) 901 193.8 2.5e-49 XP_006715142 (OMIM: 146880,212750) PREDICTED: HLA ( 206) 714 155.5 6.9e-38 NP_006111 (OMIM: 142855) HLA class II histocompati ( 261) 339 78.9 9.8e-15 NP_002109 (OMIM: 142856) HLA class II histocompati ( 263) 263 63.4 4.7e-10 NP_002112 (OMIM: 142858) HLA class II histocompati ( 258) 254 61.5 1.7e-09 NP_001287719 (OMIM: 615161) HLA class II histocomp ( 264) 236 57.9 2.2e-08 XP_005249108 (OMIM: 615161) PREDICTED: HLA class I ( 275) 236 57.9 2.2e-08 XP_011512862 (OMIM: 615161) PREDICTED: HLA class I ( 256) 234 57.5 2.8e-08 NP_001230894 (OMIM: 126200,142857,180300,181000) m ( 266) 233 57.3 3.3e-08 NP_001185787 (OMIM: 615161) HLA class II histocomp ( 227) 228 56.2 6e-08 XP_011546040 (OMIM: 126200,142857,180300,181000) P ( 266) 225 55.6 1e-07 NP_620578 (OMIM: 104300,176100,176200,235200,61263 ( 325) 224 55.5 1.4e-07 NP_001287678 (OMIM: 104300,176100,176200,235200,61 ( 337) 224 55.5 1.4e-07 XP_011512845 (OMIM: 104300,176100,176200,235200,61 ( 348) 224 55.5 1.5e-07 NP_000401 (OMIM: 104300,176100,176200,235200,61263 ( 348) 224 55.5 1.5e-07 NP_620576 (OMIM: 104300,176100,176200,235200,61263 ( 260) 220 54.6 2.1e-07 NP_001230890 (OMIM: 123400,126200,212750,604305) H ( 269) 219 54.4 2.4e-07 NP_001230891 (OMIM: 123400,126200,212750,604305) H ( 261) 217 54.0 3.2e-07 NP_002114 (OMIM: 123400,126200,212750,604305) HLA ( 261) 217 54.0 3.2e-07 XP_011512863 (OMIM: 615161) PREDICTED: HLA class I ( 219) 216 53.7 3.2e-07 NP_002116 (OMIM: 604776) major histocompatibility ( 266) 215 53.6 4.3e-07 XP_011512864 (OMIM: 604776) PREDICTED: major histo ( 276) 215 53.6 4.4e-07 XP_016866306 (OMIM: 142871,600807) PREDICTED: HLA ( 246) 213 53.1 5.4e-07 XP_016866307 (OMIM: 142871,600807) PREDICTED: HLA ( 246) 213 53.1 5.4e-07 NP_072049 (OMIM: 612735) major histocompatibility ( 266) 209 52.4 1e-06 NP_002115 (OMIM: 126200,142857,180300,181000) majo ( 266) 209 52.4 1e-06 NP_620573 (OMIM: 104300,176100,176200,235200,61263 ( 256) 208 52.1 1.1e-06 XP_016866304 (OMIM: 143110) PREDICTED: HLA class I ( 228) 205 51.5 1.6e-06 NP_620579 (OMIM: 104300,176100,176200,235200,61263 ( 168) 202 50.7 1.9e-06 XP_016866303 (OMIM: 143110) PREDICTED: HLA class I ( 324) 205 51.6 2e-06 NP_061823 (OMIM: 143110) HLA class I histocompatib ( 346) 205 51.6 2.1e-06 XP_016866302 (OMIM: 143110) PREDICTED: HLA class I ( 388) 205 51.7 2.3e-06 XP_016866301 (OMIM: 143110) PREDICTED: HLA class I ( 420) 205 51.7 2.5e-06 XP_016866299 (OMIM: 143110) PREDICTED: HLA class I ( 435) 205 51.7 2.5e-06 NP_001091949 (OMIM: 143110) HLA class I histocompa ( 442) 205 51.7 2.6e-06 XP_016866300 (OMIM: 143110) PREDICTED: HLA class I ( 431) 198 50.3 6.8e-06 NP_620572 (OMIM: 104300,176100,176200,235200,61263 ( 242) 194 49.3 7.8e-06 NP_620577 (OMIM: 104300,176100,176200,235200,61263 ( 246) 194 49.3 7.9e-06 NP_620575 (OMIM: 104300,176100,176200,235200,61263 ( 334) 194 49.4 9.9e-06 XP_011512866 (OMIM: 143110) PREDICTED: HLA class I ( 343) 194 49.4 1e-05 NP_002107 (OMIM: 142800,608579) HLA class I histoc ( 365) 194 49.4 1.1e-05 NP_001229687 (OMIM: 142800,608579) HLA class I his ( 365) 194 49.4 1.1e-05 NP_004039 (OMIM: 105200,109700,241600) beta-2-micr ( 119) 188 47.8 1.1e-05 NP_005505 (OMIM: 106300,142830,608579) major histo ( 362) 190 48.6 1.9e-05 >>NP_061984 (OMIM: 142860) HLA class II histocompatibili (254 aa) initn: 1707 init1: 1707 opt: 1707 Z-score: 1897.1 bits: 358.6 E(85289): 6.2e-99 Smith-Waterman score: 1707; 100.0% identity (100.0% similar) in 254 aa overlap (1-254:1-254) 10 20 30 40 50 60 pF1KE0 MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 MAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 MAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 PVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 PVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 STEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFIIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 STEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFIIK 190 200 210 220 230 240 250 pF1KE0 GLRKSNAAERRGPL :::::::::::::: NP_061 GLRKSNAAERRGPL 250 >>NP_291032 (OMIM: 142880) HLA class II histocompatibili (260 aa) initn: 1002 init1: 976 opt: 998 Z-score: 1113.6 bits: 213.7 E(85289): 2.7e-55 Smith-Waterman score: 998; 59.9% identity (80.6% similar) in 247 aa overlap (8-254:14-260) 10 20 30 40 50 pF1KE0 MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSGEFMFDFDGD .: . .: :.: . . ::: .:: : : . .:::::.:: : NP_291 MRPEDRMFHIRAVILRALSLAFLLSLRGAGAIKADHVSTYAAFVQTHRPTGEFMFEFDED 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 EIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEV :.:.::. ::::::.:::::. ::::::.:::::. . ::. . .:::.: :: :::: NP_291 EMFYVDLDKKETVWHLEEFGQAFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEV 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 TVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFH ::. . :::: .::.::: :::: :::.::::: ::. :: ::.:..:::: :. :.::: NP_291 TVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFH 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 YLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIG :: :.::.:: :::::::::::.::::::: . : .:::::.:.:::::..::::::.: NP_291 YLTFVPSAEDFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVG 190 200 210 220 230 240 240 250 pF1KE0 TIFIIKGLRKSNAAERRGPL :..:::.::... . .: : NP_291 TVLIIKSLRSGHDPRAQGTL 250 260 >>NP_001229453 (OMIM: 142880) HLA class II histocompatib (260 aa) initn: 1002 init1: 976 opt: 998 Z-score: 1113.6 bits: 213.7 E(85289): 2.7e-55 Smith-Waterman score: 998; 59.9% identity (80.6% similar) in 247 aa overlap (8-254:14-260) 10 20 30 40 50 pF1KE0 MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSGEFMFDFDGD .: . .: :.: . . ::: .:: : : . .:::::.:: : NP_001 MRPEDRMFHIRAVILRALSLAFLLSLRGAGAIKADHVSTYAAFVQTHRPTGEFMFEFDED 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 EIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEV :.:.::. ::::::.:::::. ::::::.:::::. . ::. . .:::.: :: :::: NP_001 EMFYVDLDKKETVWHLEEFGQAFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEV 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 TVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFH ::. . :::: .::.::: :::: :::.::::: ::. :: ::.:..:::: :. :.::: NP_001 TVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFH 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 YLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIG :: :.::.:: :::::::::::.::::::: . : .:::::.:.:::::..::::::.: NP_001 YLTFVPSAEDFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVG 190 200 210 220 230 240 240 250 pF1KE0 TIFIIKGLRKSNAAERRGPL :..:::.::... . .: : NP_001 TVLIIKSLRSGHDPRAQGTL 250 260 >>NP_001229454 (OMIM: 142880) HLA class II histocompatib (260 aa) initn: 1002 init1: 976 opt: 998 Z-score: 1113.6 bits: 213.7 E(85289): 2.7e-55 Smith-Waterman score: 998; 59.9% identity (80.6% similar) in 247 aa overlap (8-254:14-260) 10 20 30 40 50 pF1KE0 MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSGEFMFDFDGD .: . .: :.: . . ::: .:: : : . .:::::.:: : NP_001 MRPEDRMFHIRAVILRALSLAFLLSLRGAGAIKADHVSTYAAFVQTHRPTGEFMFEFDED 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 EIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEV :.:.::. ::::::.:::::. ::::::.:::::. . ::. . .:::.: :: :::: NP_001 EMFYVDLDKKETVWHLEEFGQAFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEV 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 TVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFH ::. . :::: .::.::: :::: :::.::::: ::. :: ::.:..:::: :. :.::: NP_001 TVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFH 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 YLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIG :: :.::.:: :::::::::::.::::::: . : .:::::.:.:::::..::::::.: NP_001 YLTFVPSAEDFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVG 190 200 210 220 230 240 240 250 pF1KE0 TIFIIKGLRKSNAAERRGPL :..:::.::... . .: : NP_001 TVLIIKSLRSGHDPRAQGTL 250 260 >>NP_002110 (OMIM: 142930) HLA class II histocompatibili (250 aa) initn: 1000 init1: 887 opt: 943 Z-score: 1053.1 bits: 202.4 E(85289): 6.4e-52 Smith-Waterman score: 943; 54.7% identity (78.9% similar) in 247 aa overlap (1-246:1-247) 10 20 30 40 50 pF1KE0 MAISGVPVLGFFIIAVLMSAQESWAIKEEHV-IIQAEFYLNPDQSGEFMFDFDGDEIFHV ::. . :::: . .:.: ::. : : .:. :: . ::.: .:: ...: : NP_002 MALRAGLVLGFHTLMTLLSPQEAGATKADHMGSYGPAFYQSYGASGQFTHEFDEEQLFSV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 DMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTN :. :.:.:::: ::: :: :. ::.::.::. ::.:.:...::: . ::::.:::: . NP_002 DLKKSEAVWRLPEFGDFARFDPQGGLAGIAAIKAHLDILVERSNRSRAINVPPRVTVLPK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 SPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFL : ::: .::.:::..:.. :::.:.::::::. :: ::..: : . ::::::::::::. NP_002 SRVELGQPNILICIVDNIFPPVINITWLRNGQTVTEGVAQTSFYSQPDHLFRKFHYLPFV 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 PSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFII ::.::::::.::::::: :::.:::...: : :.. :..::::::..::::...::..:: NP_002 PSAEDVYDCQVEHWGLDAPLLRHWELQVPIPPPDAMETLVCALGLAIGLVGFLVGTVLII 190 200 210 220 230 240 240 250 pF1KE0 KGLRKSNAAERRGPL : :. NP_002 MGTYVSSVPR 250 >>NP_002113 (OMIM: 146880,212750) HLA class II histocomp (255 aa) initn: 931 init1: 913 opt: 929 Z-score: 1037.5 bits: 199.5 E(85289): 4.7e-51 Smith-Waterman score: 929; 53.3% identity (78.0% similar) in 255 aa overlap (1-254:1-255) 10 20 30 40 50 pF1KE0 MAISGVPVLGFFIIAVLMSAQESWAIKEEHVI-IQAEFYLNPDQSGEFMFDFDGDEIFHV : .. . .:: . ....:: . : .:: ...: ::.. .::::: :.: NP_002 MILNKALLLGALALTTVMSPCGGEDIVADHVASCGVNLYQFYGPSGQYTHEFDGDEQFYV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 DMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTN :. .:::.:: ::..:..:. :::: :.:: : ::.:: :: : : :: :::::... NP_002 DLERKETAWRWPEFSKFGGFDPQGALRNMAVAKHNLNIMIKRYNSTAATNEVPEVTVFSK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 SPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFL ::: : .::.:::..:.. :::::.::: ::. :: ::::: :: . :: : :. :: :: NP_002 SPVTLGQPNTLICLVDNIFPPVVNITWLSNGQSVTEGVSETSFLSKSDHSFFKISYLTFL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 PSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFII ::....:::.:::::::.::::::: . :.:. : ::.:::::::.:::.::..::.::: NP_002 PSADEIYDCKVEHWGLDQPLLKHWEPEIPAPMSELTETVVCALGLSVGLMGIVVGTVFII 190 200 210 220 230 240 240 250 pF1KE0 KGLRKSNAAERRGPL .:::. .:....::: NP_002 QGLRSVGASRHQGPL 250 >>NP_064440 (OMIM: 613503) HLA class II histocompatibili (255 aa) initn: 976 init1: 882 opt: 901 Z-score: 1006.6 bits: 193.8 E(85289): 2.5e-49 Smith-Waterman score: 901; 52.2% identity (77.3% similar) in 255 aa overlap (1-254:1-255) 10 20 30 40 50 pF1KE0 MAISGVPVLGFFIIAVLMSAQESWAIKEEHVI-IQAEFYLNPDQSGEFMFDFDGDEIFHV : .. . .:: . ....:: . : .:: ..:: . ::.. .::::: :.: NP_064 MILNKALLLGALALTAVMSPCGGEDIVADHVASYGVNFYQSHGPSGQYTHEFDGDEEFYV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 DMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTN :. :::::.: :..: ::. :.:: :.:: : .::.: ..:: : :: :::::... NP_064 DLETKETVWQLPMFSKFISFDPQSALRNMAVGKHTLEFMMRQSNSTAATNEVPEVTVFSK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 SPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFL :: : .::.:::..:.. :::::.::: ::. :: ::::: :: . :: : :. :: :: NP_064 FPVTLGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTFL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 PSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFII ::....:::.::::::::::::::: . :.:. : ::..::::::.:::.::..::.::: NP_064 PSADEIYDCKVEHWGLDEPLLKHWEPEIPAPMSELTETLVCALGLSVGLMGIVVGTVFII 190 200 210 220 230 240 240 250 pF1KE0 KGLRKSNAAERRGPL .:::. .:....: : NP_064 QGLRSVGASRHQGLL 250 >>XP_006715142 (OMIM: 146880,212750) PREDICTED: HLA clas (206 aa) initn: 716 init1: 698 opt: 714 Z-score: 801.2 bits: 155.5 E(85289): 6.9e-38 Smith-Waterman score: 714; 52.0% identity (75.0% similar) in 204 aa overlap (1-203:1-204) 10 20 30 40 50 pF1KE0 MAISGVPVLGFFIIAVLMSAQESWAIKEEHVI-IQAEFYLNPDQSGEFMFDFDGDEIFHV : .. . .:: . ....:: . : .:: ...: ::.. .::::: :.: XP_006 MILNKALLLGALALTTVMSPCGGEDIVADHVASCGVNLYQFYGPSGQYTHEFDGDEQFYV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 DMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTN :. .:::.:: ::..:..:. :::: :.:: : ::.:: :: : : :: :::::... XP_006 DLERKETAWRWPEFSKFGGFDPQGALRNMAVAKHNLNIMIKRYNSTAATNEVPEVTVFSK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 SPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFL ::: : .::.:::..:.. :::::.::: ::. :: ::::: :: . :: : :. :: :: XP_006 SPVTLGQPNTLICLVDNIFPPVVNITWLSNGQSVTEGVSETSFLSKSDHSFFKISYLTFL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 PSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFII ::....:::.:::::::.:::::: XP_006 PSADEIYDCKVEHWGLDQPLLKHWVE 190 200 >>NP_006111 (OMIM: 142855) HLA class II histocompatibili (261 aa) initn: 199 init1: 126 opt: 339 Z-score: 385.5 bits: 78.9 E(85289): 9.8e-15 Smith-Waterman score: 341; 28.9% identity (58.1% similar) in 246 aa overlap (13-239:14-252) 10 20 30 40 pF1KE0 MAISGVPVLGFFIIAVLMSAQESWAIKE-----------EHVIIQAEFYLNPDQSGEFM .. .: .:::. : .:..... . . . : . NP_006 MGHEQNQGAALLQMLPLLWLLPHSWAVPEAPTPMWPDDLQNHTFLHTVYCQDGSPSVGLS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 FDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKR-----SN .: :..: :.... : :: ::. .: . :: : :: : : .. .. NP_006 EAYDEDQLFFFDFSQNTRVPRLPEFADWA--QEQGDAPAILFDKEFCEWMIQQIGPKLDG 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 YTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFL :.. : . :.: .:.:. .::.:.::.... ::...:.: ... :: : . : :. NP_006 KIPVSRGFPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNWQHHSVPVE-GFGPT-FV 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 PREDHL-FRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAP-SPLP-ETTENVVC : : :. : :: : : :...: : : . .: .: . :: . :::.: NP_006 SAVDGLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYW---VPRNALPSDLLENVLC 180 190 200 210 220 230 230 240 250 pF1KE0 ALGLTVGLVGIIIGTIFIIKGLRKSNAAERRGPL .... .:..:::.: ..:: NP_006 GVAFGLGVLGIIVGIVLIIYFRKPCSGD 240 250 260 >>NP_002109 (OMIM: 142856) HLA class II histocompatibili (263 aa) initn: 241 init1: 137 opt: 263 Z-score: 301.5 bits: 63.4 E(85289): 4.7e-10 Smith-Waterman score: 263; 36.2% identity (59.1% similar) in 127 aa overlap (111-236:114-238) 90 100 110 120 130 140 pF1KE0 AQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPP :: : : ..: . ::: .: :.. : : NP_002 DTLMQRLRNGLQNCATHTQPFWGSLTNRTRPPSVQVAKTTPFNTREPVMLACYVWGFYPA 90 100 110 120 130 140 150 160 170 180 190 pF1KE0 VVNVTWLRNGKPVTTGVS-ETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPL :..:: .::: : : . . : : .. . .: . :: :.: : ::: : ::. NP_002 EVTITWRKNGKLVMPHSSAHKTAQPNGDWTYQTLSHLALTPSYGDTYTCVVEHTGAPEPI 150 160 170 180 190 200 200 210 220 230 240 250 pF1KE0 LKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFIIKGLRKSNAAERRGPL :. : . ::. .: . : :. : .::. . .:.: NP_002 LRDWT-PGLSPM-QTLKVSVSAVTLGLGLIIFSLGVISWRRAGHSSYTPLPGSNYSEGWH 210 220 230 240 250 260 NP_002 IS 254 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:28:27 2016 done: Sat Nov 5 04:28:28 2016 Total Scan time: 6.690 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]