FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0915, 263 aa 1>>>pF1KE0915 263 - 263 aa - 263 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5434+/-0.000808; mu= 13.2721+/- 0.048 mean_var=61.6781+/-12.390, 0's: 0 Z-trim(107.0): 27 B-trim: 0 in 0/48 Lambda= 0.163309 statistics sampled from 9281 (9305) to 9281 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.665), E-opt: 0.2 (0.286), width: 16 Scan time: 2.040 The best scores are: opt bits E(32554) CCDS9584.1 PSMB5 gene_id:5693|Hs108|chr14 ( 263) 1750 420.6 5.4e-118 CCDS45084.1 PSMB5 gene_id:5693|Hs108|chr14 ( 203) 1122 272.6 1.5e-73 CCDS45083.1 PSMB5 gene_id:5693|Hs108|chr14 ( 160) 1078 262.2 1.6e-70 CCDS4757.1 PSMB8 gene_id:5696|Hs108|chr6 ( 276) 1010 246.3 1.7e-65 CCDS4756.1 PSMB8 gene_id:5696|Hs108|chr6 ( 272) 1009 246.0 2e-65 CCDS41923.1 PSMB11 gene_id:122706|Hs108|chr14 ( 300) 771 190.0 1.7e-48 CCDS11056.1 PSMB6 gene_id:5694|Hs108|chr17 ( 239) 343 89.1 3.1e-18 CCDS4759.1 PSMB9 gene_id:5698|Hs108|chr6 ( 219) 313 82.0 3.8e-16 CCDS73944.1 PSMB6 gene_id:5694|Hs108|chr17 ( 213) 293 77.3 9.7e-15 CCDS6855.1 PSMB7 gene_id:5695|Hs108|chr9 ( 277) 294 77.6 1e-14 CCDS10853.1 PSMB10 gene_id:5699|Hs108|chr16 ( 273) 280 74.3 1e-13 >>CCDS9584.1 PSMB5 gene_id:5693|Hs108|chr14 (263 aa) initn: 1750 init1: 1750 opt: 1750 Z-score: 2231.8 bits: 420.6 E(32554): 5.4e-118 Smith-Waterman score: 1750; 100.0% identity (100.0% similar) in 263 aa overlap (1-263:1-263) 10 20 30 40 50 60 pF1KE0 MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 TTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 TTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 QCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 QCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 SGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 SGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVRE 190 200 210 220 230 240 250 260 pF1KE0 DGWIRVSSDNVADLHEKYSGSTP ::::::::::::::::::::::: CCDS95 DGWIRVSSDNVADLHEKYSGSTP 250 260 >>CCDS45084.1 PSMB5 gene_id:5693|Hs108|chr14 (203 aa) initn: 1122 init1: 1122 opt: 1122 Z-score: 1434.0 bits: 272.6 E(32554): 1.5e-73 Smith-Waterman score: 1122; 100.0% identity (100.0% similar) in 168 aa overlap (1-168:1-168) 10 20 30 40 50 60 pF1KE0 MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 TTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 TTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 QCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRI :::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 QCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPVSEVLCLKPKSF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 SGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVRE CCDS45 GMYLFCGCAERIGNMARPLLRGQ 190 200 >>CCDS45083.1 PSMB5 gene_id:5693|Hs108|chr14 (160 aa) initn: 1078 init1: 1078 opt: 1078 Z-score: 1379.7 bits: 262.2 E(32554): 1.6e-70 Smith-Waterman score: 1078; 100.0% identity (100.0% similar) in 160 aa overlap (104-263:1-160) 80 90 100 110 120 130 pF1KE0 AADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERI :::::::::::::::::::::::::::::: CCDS45 MAGGAADCSFWERLLARQCRIYELRNKERI 10 20 30 140 150 160 170 180 190 pF1KE0 SVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 SVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVY 40 50 60 70 80 90 200 210 220 230 240 250 pF1KE0 AYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 AYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVAD 100 110 120 130 140 150 260 pF1KE0 LHEKYSGSTP :::::::::: CCDS45 LHEKYSGSTP 160 >>CCDS4757.1 PSMB8 gene_id:5696|Hs108|chr6 (276 aa) initn: 1028 init1: 1009 opt: 1010 Z-score: 1289.2 bits: 246.3 E(32554): 1.7e-65 Smith-Waterman score: 1010; 62.0% identity (83.9% similar) in 242 aa overlap (17-258:31-271) 10 20 30 40 pF1KE0 MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGW : .... :. : : : ... . . : CCDS47 MALLDVCGAPRGQRPESALPVAGSGRRSDPGHYSFSMRSPELAL-PRGMQPTEFFQSLGG 10 20 30 40 50 50 60 70 80 90 100 pF1KE0 GVPEEPGIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAG .. ::: ::::::::::.::::.:.::::.::.::.. :.:::::::::::::.: CCDS47 DGERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSG 60 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 GAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKR ::::..::::::..::.: ::: :::::.::::::.::. ::.:::::::.:::::::. CCDS47 CAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKK 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 GPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRD :::::::: .:.:.:: ::.:::..::::::: :: .: :.::::.:::: ::.:: CCDS47 GPGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRD 180 190 200 210 220 230 230 240 250 260 pF1KE0 AYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSGSTP .::::.::.::..::::..: : .:.:: ..: CCDS47 SYSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ 240 250 260 270 >>CCDS4756.1 PSMB8 gene_id:5696|Hs108|chr6 (272 aa) initn: 1028 init1: 1009 opt: 1009 Z-score: 1288.1 bits: 246.0 E(32554): 2e-65 Smith-Waterman score: 1009; 70.2% identity (90.2% similar) in 205 aa overlap (54-258:63-267) 30 40 50 60 70 80 pF1KE0 RADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGTTTLAFKFRHGVIVAADSRATAGA ::: ::::::::::.::::.:.::::.::. CCDS47 LPTPVSSGCPGLEPTEFFQSLGGDGERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGS 40 50 60 70 80 90 90 100 110 120 130 140 pF1KE0 YIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLA ::.. :.:::::::::::::.: ::::..::::::..::.: ::: :::::.::::::. CCDS47 YISALRVNKVIEINPYLLGTMSGCAADCQYWERLLAKECRLYYLRNGERISVSAASKLLS 100 110 120 130 140 150 150 160 170 180 190 200 pF1KE0 NMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYS ::. ::.:::::::.:::::::.:::::::: .:.:.:: ::.:::..::::::: :: CCDS47 NMMCQYRGMGLSMGSMICGWDKKGPGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYR 160 170 180 190 200 210 210 220 230 240 250 260 pF1KE0 YDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSGSTP .: :.::::.:::: ::.::.::::.::.::..::::..: : .:.:: ..: CCDS47 PNLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ 220 230 240 250 260 270 >>CCDS41923.1 PSMB11 gene_id:122706|Hs108|chr14 (300 aa) initn: 790 init1: 763 opt: 771 Z-score: 984.3 bits: 190.0 E(32554): 1.7e-48 Smith-Waterman score: 786; 52.7% identity (77.9% similar) in 222 aa overlap (43-255:24-245) 20 30 40 50 60 pF1KE0 VNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPE--EP-------GIEMLHGTTTL : ::.::. .: : .. :::::: CCDS41 MALQDVCKWQSPDTQGPSPHLPRAGGWAVPRGCDPQTFLQIHGPRLAHGTTTL 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 AFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCR ::.::::::.:::.:.. :.:.: . ::: .. .:::: .: .:::. : :.: :. : CCDS41 AFRFRHGVIAAADTRSSCGSYVACPASCKVIPVHQHLLGTTSGTSADCATWYRVLQRELR 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 IYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGA . :::. . :::.:.:::. :. ::.:. : ..: .::::. :: :.:: :.:.:..: CCDS41 LRELREGQLPSVASAAKLLSAMMSQYRGLDLCVATALCGWDRSGPELFYVYSDGTRLQGD 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 TFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGW ::::::: :::::.:::: ::. ...:: ::: :. .::.:::::::.:.:.::::.:: CCDS41 IFSVGSGSPYAYGVLDRGYRYDMSTQEAYALARCAVAHATHRDAYSGGSVDLFHVRESGW 180 190 200 210 220 230 250 260 pF1KE0 IRVSSDNVADLHEKYSGSTP .:: ... :. CCDS41 EHVSRSDACVLYVELQKLLEPEPEEDASHAHPEPATAHRAAEDRELSVGPGEVTPGDSRM 240 250 260 270 280 290 >>CCDS11056.1 PSMB6 gene_id:5694|Hs108|chr17 (239 aa) initn: 318 init1: 262 opt: 343 Z-score: 441.0 bits: 89.1 E(32554): 3.1e-18 Smith-Waterman score: 343; 32.2% identity (60.0% similar) in 205 aa overlap (43-242:14-217) 20 30 40 50 60 pF1KE0 VNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWG----VPEEPGIEMLHGTTTLAFKFR ::.:: .:. . :. ::: .: .: CCDS11 MAATLLAARGAGPAPAWGPEAFTPDWESREVSTGTTIMAVQFD 10 20 30 40 70 80 90 100 110 120 pF1KE0 HGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELR ::...::::.:.:.:::.... :. :. .. .:.::: . .. : .. .. CCDS11 GGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 NKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVG .: : .:..:. .: :.:. : : .: ::: . : : :. . .:..: CCDS11 LNEPPLVHTAASLFKEMCYRYR-EDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIG 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE0 -SGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVS ::: : :: .: : . :. ... :. : ::. :::.. : . :.: CCDS11 GSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRLAAIAESGVERQV 170 180 190 200 210 220 250 260 pF1KE0 SDNVADLHEKYSGSTP CCDS11 LLGDQIPKFAVATLPPA 230 >>CCDS4759.1 PSMB9 gene_id:5698|Hs108|chr6 (219 aa) initn: 326 init1: 155 opt: 313 Z-score: 403.4 bits: 82.0 E(32554): 3.8e-16 Smith-Waterman score: 313; 30.2% identity (60.0% similar) in 205 aa overlap (39-242:2-202) 10 20 30 40 50 60 pF1KE0 RPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGTTTLAFKFR : .:: .:. : :. ::: .: .: CCDS47 MLRAGAPTGDLPRA-G-EVHTGTTIMAVEFD 10 20 70 80 90 100 110 120 pF1KE0 HGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELR ::....:::..:: ..... :. .. . ...:.::: . . : : ... .. CCDS47 GGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADMAAYQLELHGIE 30 40 50 60 70 80 130 140 150 160 170 180 pF1KE0 NKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVG .: : ::.... :. :.:. :: :. :::.: : : . :. .. :..: CCDS47 LEEPPLVLAAANVVRNISYKYR-EDLSAHLMVAGWDQREGGQVY-GTLGGMLTRQPFAIG 90 100 110 120 130 140 190 200 210 220 230 240 pF1KE0 -SGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVS :::.. :: .: .:. . :. .. :: : ::. :::.. : . : CCDS47 GSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVIYLVTITAAGVDHRV 150 160 170 180 190 200 250 260 pF1KE0 SDNVADLHEKYSGSTP CCDS47 ILGNELPKFYDE 210 >>CCDS73944.1 PSMB6 gene_id:5694|Hs108|chr17 (213 aa) initn: 260 init1: 204 opt: 293 Z-score: 378.1 bits: 77.3 E(32554): 9.7e-15 Smith-Waterman score: 293; 31.1% identity (60.1% similar) in 183 aa overlap (43-220:14-195) 20 30 40 50 60 pF1KE0 VNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWG----VPEEPGIEMLHGTTTLAFKFR ::.:: .:. . :. ::: .: .: CCDS73 MAATLLAARGAGPAPAWGPEAFTPDWESREVSTGTTIMAVQFD 10 20 30 40 70 80 90 100 110 120 pF1KE0 HGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELR ::...::::.:.:.:::.... :. :. .. .:.::: . .. : .. .. CCDS73 GGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 NKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVG .: : .:..:. .: :.:. : : .: ::: . : : :. . .:..: CCDS73 LNEPPLVHTAASLFKEMCYRYR-EDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIG 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE0 -SGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVS ::: : :: .: : . :. ... :.. CCDS73 GSGSSYIYGYVDATYREGMTKEECLQFTANAFFFYPQLSLWPWSGMAPVEE 170 180 190 200 210 250 260 pF1KE0 SDNVADLHEKYSGSTP >>CCDS6855.1 PSMB7 gene_id:5695|Hs108|chr9 (277 aa) initn: 232 init1: 125 opt: 294 Z-score: 377.5 bits: 77.6 E(32554): 1e-14 Smith-Waterman score: 294; 28.8% identity (65.5% similar) in 177 aa overlap (59-235:43-218) 30 40 50 60 70 80 pF1KE0 DLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQ ::: . .. :....::.::: : .:.. CCDS68 GFSFDNCRRNAVLEADFAKRGYKLPKVRKTGTTIAGVVYKDGIVLGADTRATEGMVVADK 20 30 40 50 60 70 90 100 110 120 130 140 pF1KE0 TVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQ . .:. :.: . :: ::: .. .:.. . ... : . . :..:...: .:... CCDS68 NCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVVTANRMLKQMLFR 80 90 100 110 120 130 150 160 170 180 190 200 pF1KE0 YKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEV :.:. .. . .. : : :: :: . .:. . ..::::. :..:.. . :.: CCDS68 YQGY-IGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEE 140 150 160 170 180 190 210 220 230 240 250 260 pF1KE0 EQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSGSTP :.: .:. .:: . . : ::. ..: CCDS68 EEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNKLDFLRPYTVPNKKGTRLGRYRCEKGT 200 210 220 230 240 250 263 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:29:01 2016 done: Sat Nov 5 04:29:02 2016 Total Scan time: 2.040 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]