FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0916, 287 aa 1>>>pF1KE0916 287 - 287 aa - 287 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6669+/-0.000299; mu= 5.5123+/- 0.019 mean_var=153.0139+/-30.148, 0's: 0 Z-trim(122.4): 31 B-trim: 2 in 1/59 Lambda= 0.103683 statistics sampled from 40347 (40385) to 40347 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.803), E-opt: 0.2 (0.474), width: 16 Scan time: 8.580 The best scores are: opt bits E(85289) NP_064567 (OMIM: 606564) protein TMEPAI isoform a ( 287) 1989 308.4 9.9e-84 NP_954638 (OMIM: 606564) protein TMEPAI isoform b ( 252) 1741 271.3 1.3e-72 NP_001242905 (OMIM: 606564) protein TMEPAI isoform ( 259) 1739 271.0 1.6e-72 NP_954639 (OMIM: 606564) protein TMEPAI isoform c ( 237) 1667 260.2 2.7e-69 NP_954640 (OMIM: 606564) protein TMEPAI isoform c ( 237) 1667 260.2 2.7e-69 XP_016881450 (OMIM: 606571) PREDICTED: low-density ( 290) 1138 181.2 2.1e-45 NP_001003674 (OMIM: 606571) low-density lipoprotei ( 269) 1122 178.7 1e-44 XP_006722417 (OMIM: 606571) PREDICTED: low-density ( 306) 1121 178.6 1.3e-44 NP_852146 (OMIM: 606571) low-density lipoprotein r ( 306) 1121 178.6 1.3e-44 XP_005258197 (OMIM: 606571) PREDICTED: low-density ( 306) 1121 178.6 1.3e-44 XP_006722416 (OMIM: 606571) PREDICTED: low-density ( 306) 1121 178.6 1.3e-44 XP_011524039 (OMIM: 606571) PREDICTED: low-density ( 259) 1119 178.3 1.4e-44 XP_016881452 (OMIM: 606571) PREDICTED: low-density ( 259) 1119 178.3 1.4e-44 XP_016881453 (OMIM: 606571) PREDICTED: low-density ( 259) 1119 178.3 1.4e-44 XP_016881458 (OMIM: 606571) PREDICTED: low-density ( 229) 1047 167.5 2.2e-41 XP_016881459 (OMIM: 606571) PREDICTED: low-density ( 229) 1047 167.5 2.2e-41 XP_016881457 (OMIM: 606571) PREDICTED: low-density ( 229) 1047 167.5 2.2e-41 XP_016881456 (OMIM: 606571) PREDICTED: low-density ( 229) 1047 167.5 2.2e-41 XP_011524040 (OMIM: 606571) PREDICTED: low-density ( 229) 1047 167.5 2.2e-41 NP_001263178 (OMIM: 606571) low-density lipoprotei ( 229) 1047 167.5 2.2e-41 XP_016881460 (OMIM: 606571) PREDICTED: low-density ( 229) 1047 167.5 2.2e-41 XP_016881455 (OMIM: 606571) PREDICTED: low-density ( 229) 1047 167.5 2.2e-41 XP_016881454 (OMIM: 606571) PREDICTED: low-density ( 229) 1047 167.5 2.2e-41 NP_001263180 (OMIM: 606571) low-density lipoprotei ( 208) 890 144.0 2.3e-34 XP_016881461 (OMIM: 606571) PREDICTED: low-density ( 211) 854 138.6 9.9e-33 NP_001003675 (OMIM: 606571) low-density lipoprotei ( 251) 854 138.6 1.1e-32 XP_016881451 (OMIM: 606571) PREDICTED: low-density ( 272) 854 138.7 1.2e-32 NP_852147 (OMIM: 606571) low-density lipoprotein r ( 288) 854 138.7 1.3e-32 >>NP_064567 (OMIM: 606564) protein TMEPAI isoform a [Hom (287 aa) initn: 1989 init1: 1989 opt: 1989 Z-score: 1624.2 bits: 308.4 E(85289): 9.9e-84 Smith-Waterman score: 1989; 100.0% identity (100.0% similar) in 287 aa overlap (1-287:1-287) 10 20 30 40 50 60 pF1KE0 MHRLMGVNSTAAAAAGQPNVSCTCNCKRSLFQSMEITELEFVQIIIIVVVMMVMVVVITC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 MHRLMGVNSTAAAAAGQPNVSCTCNCKRSLFQSMEITELEFVQIIIIVVVMMVMVVVITC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 LLSHYKLSARSFISRHSQGRRREDALSSEGCLWPSESTVSGNGIPEPQVYAPPRPTDRLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 LLSHYKLSARSFISRHSQGRRREDALSSEGCLWPSESTVSGNGIPEPQVYAPPRPTDRLA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VPPFAQRERFHRFQPTYPYLQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 VPPFAQRERFHRFQPTYPYLQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ESVRAPPNRTIFDSDLMDSARLGGPCPPSSNSGISATCYGSGGRMEGPPPTYSEVIGHYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 ESVRAPPNRTIFDSDLMDSARLGGPCPPSSNSGISATCYGSGGRMEGPPPTYSEVIGHYP 190 200 210 220 230 240 250 260 270 280 pF1KE0 GSSFQHQQSSGPPSLLEGTRLHHTHIAPLESAAIWSKEKDKQKGHPL ::::::::::::::::::::::::::::::::::::::::::::::: NP_064 GSSFQHQQSSGPPSLLEGTRLHHTHIAPLESAAIWSKEKDKQKGHPL 250 260 270 280 >>NP_954638 (OMIM: 606564) protein TMEPAI isoform b [Hom (252 aa) initn: 1741 init1: 1741 opt: 1741 Z-score: 1424.6 bits: 271.3 E(85289): 1.3e-72 Smith-Waterman score: 1741; 99.2% identity (100.0% similar) in 252 aa overlap (36-287:1-252) 10 20 30 40 50 60 pF1KE0 GVNSTAAAAAGQPNVSCTCNCKRSLFQSMEITELEFVQIIIIVVVMMVMVVVITCLLSHY ..:::::::::::::::::::::::::::: NP_954 MAELEFVQIIIIVVVMMVMVVVITCLLSHY 10 20 30 70 80 90 100 110 120 pF1KE0 KLSARSFISRHSQGRRREDALSSEGCLWPSESTVSGNGIPEPQVYAPPRPTDRLAVPPFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_954 KLSARSFISRHSQGRRREDALSSEGCLWPSESTVSGNGIPEPQVYAPPRPTDRLAVPPFA 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 QRERFHRFQPTYPYLQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNRESVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_954 QRERFHRFQPTYPYLQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNRESVRA 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE0 PPNRTIFDSDLMDSARLGGPCPPSSNSGISATCYGSGGRMEGPPPTYSEVIGHYPGSSFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_954 PPNRTIFDSDLMDSARLGGPCPPSSNSGISATCYGSGGRMEGPPPTYSEVIGHYPGSSFQ 160 170 180 190 200 210 250 260 270 280 pF1KE0 HQQSSGPPSLLEGTRLHHTHIAPLESAAIWSKEKDKQKGHPL :::::::::::::::::::::::::::::::::::::::::: NP_954 HQQSSGPPSLLEGTRLHHTHIAPLESAAIWSKEKDKQKGHPL 220 230 240 250 >>NP_001242905 (OMIM: 606564) protein TMEPAI isoform d [ (259 aa) initn: 1739 init1: 1739 opt: 1739 Z-score: 1422.8 bits: 271.0 E(85289): 1.6e-72 Smith-Waterman score: 1739; 100.0% identity (100.0% similar) in 250 aa overlap (38-287:10-259) 10 20 30 40 50 60 pF1KE0 NSTAAAAAGQPNVSCTCNCKRSLFQSMEITELEFVQIIIIVVVMMVMVVVITCLLSHYKL :::::::::::::::::::::::::::::: NP_001 MPAIPAHGAELEFVQIIIIVVVMMVMVVVITCLLSHYKL 10 20 30 70 80 90 100 110 120 pF1KE0 SARSFISRHSQGRRREDALSSEGCLWPSESTVSGNGIPEPQVYAPPRPTDRLAVPPFAQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SARSFISRHSQGRRREDALSSEGCLWPSESTVSGNGIPEPQVYAPPRPTDRLAVPPFAQR 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 ERFHRFQPTYPYLQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNRESVRAPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERFHRFQPTYPYLQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNRESVRAPP 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE0 NRTIFDSDLMDSARLGGPCPPSSNSGISATCYGSGGRMEGPPPTYSEVIGHYPGSSFQHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NRTIFDSDLMDSARLGGPCPPSSNSGISATCYGSGGRMEGPPPTYSEVIGHYPGSSFQHQ 160 170 180 190 200 210 250 260 270 280 pF1KE0 QSSGPPSLLEGTRLHHTHIAPLESAAIWSKEKDKQKGHPL :::::::::::::::::::::::::::::::::::::::: NP_001 QSSGPPSLLEGTRLHHTHIAPLESAAIWSKEKDKQKGHPL 220 230 240 250 >>NP_954639 (OMIM: 606564) protein TMEPAI isoform c prec (237 aa) initn: 1667 init1: 1667 opt: 1667 Z-score: 1365.1 bits: 260.2 E(85289): 2.7e-69 Smith-Waterman score: 1667; 100.0% identity (100.0% similar) in 237 aa overlap (51-287:1-237) 30 40 50 60 70 80 pF1KE0 SCTCNCKRSLFQSMEITELEFVQIIIIVVVMMVMVVVITCLLSHYKLSARSFISRHSQGR :::::::::::::::::::::::::::::: NP_954 MMVMVVVITCLLSHYKLSARSFISRHSQGR 10 20 30 90 100 110 120 130 140 pF1KE0 RREDALSSEGCLWPSESTVSGNGIPEPQVYAPPRPTDRLAVPPFAQRERFHRFQPTYPYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_954 RREDALSSEGCLWPSESTVSGNGIPEPQVYAPPRPTDRLAVPPFAQRERFHRFQPTYPYL 40 50 60 70 80 90 150 160 170 180 190 200 pF1KE0 QHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNRESVRAPPNRTIFDSDLMDSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_954 QHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNRESVRAPPNRTIFDSDLMDSA 100 110 120 130 140 150 210 220 230 240 250 260 pF1KE0 RLGGPCPPSSNSGISATCYGSGGRMEGPPPTYSEVIGHYPGSSFQHQQSSGPPSLLEGTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_954 RLGGPCPPSSNSGISATCYGSGGRMEGPPPTYSEVIGHYPGSSFQHQQSSGPPSLLEGTR 160 170 180 190 200 210 270 280 pF1KE0 LHHTHIAPLESAAIWSKEKDKQKGHPL ::::::::::::::::::::::::::: NP_954 LHHTHIAPLESAAIWSKEKDKQKGHPL 220 230 >>NP_954640 (OMIM: 606564) protein TMEPAI isoform c prec (237 aa) initn: 1667 init1: 1667 opt: 1667 Z-score: 1365.1 bits: 260.2 E(85289): 2.7e-69 Smith-Waterman score: 1667; 100.0% identity (100.0% similar) in 237 aa overlap (51-287:1-237) 30 40 50 60 70 80 pF1KE0 SCTCNCKRSLFQSMEITELEFVQIIIIVVVMMVMVVVITCLLSHYKLSARSFISRHSQGR :::::::::::::::::::::::::::::: NP_954 MMVMVVVITCLLSHYKLSARSFISRHSQGR 10 20 30 90 100 110 120 130 140 pF1KE0 RREDALSSEGCLWPSESTVSGNGIPEPQVYAPPRPTDRLAVPPFAQRERFHRFQPTYPYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_954 RREDALSSEGCLWPSESTVSGNGIPEPQVYAPPRPTDRLAVPPFAQRERFHRFQPTYPYL 40 50 60 70 80 90 150 160 170 180 190 200 pF1KE0 QHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNRESVRAPPNRTIFDSDLMDSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_954 QHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNRESVRAPPNRTIFDSDLMDSA 100 110 120 130 140 150 210 220 230 240 250 260 pF1KE0 RLGGPCPPSSNSGISATCYGSGGRMEGPPPTYSEVIGHYPGSSFQHQQSSGPPSLLEGTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_954 RLGGPCPPSSNSGISATCYGSGGRMEGPPPTYSEVIGHYPGSSFQHQQSSGPPSLLEGTR 160 170 180 190 200 210 270 280 pF1KE0 LHHTHIAPLESAAIWSKEKDKQKGHPL ::::::::::::::::::::::::::: NP_954 LHHTHIAPLESAAIWSKEKDKQKGHPL 220 230 >>XP_016881450 (OMIM: 606571) PREDICTED: low-density lip (290 aa) initn: 821 init1: 559 opt: 1138 Z-score: 936.2 bits: 181.2 E(85289): 2.1e-45 Smith-Waterman score: 1138; 64.0% identity (81.6% similar) in 272 aa overlap (15-285:25-288) 10 20 30 40 50 pF1KE0 MHRLMGVNSTAAAAAGQPNVSCTCNCKRSLFQSMEITELEFVQIIIIVVV :.. : . . .: :. :. .:::::.:::::::: XP_016 MLSQEPGGRERAKRGAAHRKRWREAAELNGGLSREC--SVHGSIAVTELEFAQIIIIVVV 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 MMVMVVVITCLLSHYKLSARSFISRHSQGRRREDALSSEGCLWPSESTVSGNGIPEPQVY . ::::::.:::.:::.:.::::.: .:.:::::.: .:::::::.:.. : : .. XP_016 VTVMVVVIVCLLNHYKVSTRSFINRPNQSRRREDGLPQEGCLWPSDSAAPRLGASE--IM 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 APPRPTDRLAVPPFAQRERFHRFQPTYPYLQHEIDLPPTISLSDGEEPPPYQGPCTLQLR :: ::...: : ::.:: ::::::::.:::::::::::::::::::::::::::::: XP_016 HAPRSRDRFTAPSFIQRDRFSRFQPTYPYVQHEIDLPPTISLSDGEEPPPYQGPCTLQLR 120 130 140 150 160 170 180 190 200 210 220 pF1KE0 DPEQQLELNRESVRAPPNRTIFDSDLMDSARL-GGPCPPSSNSGISATCYGSGGRMEGPP :::::.::::::::::::::::::::.: : ::::::::::::::. .:.::::::: XP_016 DPEQQMELNRESVRAPPNRTIFDSDLIDIAMYSGGPCPPSSNSGISASTCSSNGRMEGPP 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 PTYSEVIGHYPGSSFQHQQSSGPPSLLEGTRLHHTHIAPLESAAIWSKEKDKQKGHPL ::::::.::.::.:: :.: :. .:.::. . ::. . : ::.. :. XP_016 PTYSEVMGHHPGASFLHHQRSNAH---RGSRLQFQQNNA-ESTIVPIKGKDRKPGNLV 240 250 260 270 280 290 >>NP_001003674 (OMIM: 606571) low-density lipoprotein re (269 aa) initn: 821 init1: 559 opt: 1122 Z-score: 923.7 bits: 178.7 E(85289): 1e-44 Smith-Waterman score: 1122; 65.6% identity (83.0% similar) in 259 aa overlap (28-285:17-267) 10 20 30 40 50 60 pF1KE0 MHRLMGVNSTAAAAAGQPNVSCTCNCKRSLFQSMEITELEFVQIIIIVVVMMVMVVVITC ..:: .. .::::.::::::::. ::::::.: NP_001 MSSDHLNNSTLKEAQFKDLF--LKKAELEFAQIIIIVVVVTVMVVVIVC 10 20 30 40 70 80 90 100 110 120 pF1KE0 LLSHYKLSARSFISRHSQGRRREDALSSEGCLWPSESTVSGNGIPEPQVYAPPRPTDRLA ::.:::.:.::::.: .:.:::::.: .:::::::.:.. : : .. :: ::.. NP_001 LLNHYKVSTRSFINRPNQSRRREDGLPQEGCLWPSDSAAPRLGASE--IMHAPRSRDRFT 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 VPPFAQRERFHRFQPTYPYLQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNR .: : ::.:: ::::::::.:::::::::::::::::::::::::::::::::::.:::: NP_001 APSFIQRDRFSRFQPTYPYVQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQMELNR 110 120 130 140 150 160 190 200 210 220 230 pF1KE0 ESVRAPPNRTIFDSDLMDSARL-GGPCPPSSNSGISATCYGSGGRMEGPPPTYSEVIGHY ::::::::::::::::.: : ::::::::::::::. .:.:::::::::::::.::. NP_001 ESVRAPPNRTIFDSDLIDIAMYSGGPCPPSSNSGISASTCSSNGRMEGPPPTYSEVMGHH 170 180 190 200 210 220 240 250 260 270 280 pF1KE0 PGSSFQHQQSSGPPSLLEGTRLHHTHIAPLESAAIWSKEKDKQKGHPL ::.:: :.: :. .:.::. . ::. . : ::.. :. NP_001 PGASFLHHQRSNAH---RGSRLQFQQNNA-ESTIVPIKGKDRKPGNLV 230 240 250 260 >>XP_006722417 (OMIM: 606571) PREDICTED: low-density lip (306 aa) initn: 821 init1: 559 opt: 1121 Z-score: 922.1 bits: 178.6 E(85289): 1.3e-44 Smith-Waterman score: 1121; 67.2% identity (83.6% similar) in 250 aa overlap (37-285:61-304) 10 20 30 40 50 60 pF1KE0 VNSTAAAAAGQPNVSCTCNCKRSLFQSMEITELEFVQIIIIVVVMMVMVVVITCLLSHYK .::::.::::::::. ::::::.:::.::: XP_006 VCNQQNDCGDNSDEENCLLVTEHPPPGIFNSELEFAQIIIIVVVVTVMVVVIVCLLNHYK 40 50 60 70 80 90 70 80 90 100 110 120 pF1KE0 LSARSFISRHSQGRRREDALSSEGCLWPSESTVSGNGIPEPQVYAPPRPTDRLAVPPFAQ .:.::::.: .:.:::::.: .:::::::.:.. : : .. :: ::...: : : XP_006 VSTRSFINRPNQSRRREDGLPQEGCLWPSDSAAPRLGASE--IMHAPRSRDRFTAPSFIQ 100 110 120 130 140 130 140 150 160 170 180 pF1KE0 RERFHRFQPTYPYLQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNRESVRAP :.:: ::::::::.:::::::::::::::::::::::::::::::::::.:::::::::: XP_006 RDRFSRFQPTYPYVQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQMELNRESVRAP 150 160 170 180 190 200 190 200 210 220 230 240 pF1KE0 PNRTIFDSDLMDSARL-GGPCPPSSNSGISATCYGSGGRMEGPPPTYSEVIGHYPGSSFQ ::::::::::.: : ::::::::::::::. .:.:::::::::::::.::.::.:: XP_006 PNRTIFDSDLIDIAMYSGGPCPPSSNSGISASTCSSNGRMEGPPPTYSEVMGHHPGASFL 210 220 230 240 250 260 250 260 270 280 pF1KE0 HQQSSGPPSLLEGTRLHHTHIAPLESAAIWSKEKDKQKGHPL :.: :. .:.::. . ::. . : ::.. :. XP_006 HHQRSNAH---RGSRLQFQQ-NNAESTIVPIKGKDRKPGNLV 270 280 290 300 >>NP_852146 (OMIM: 606571) low-density lipoprotein recep (306 aa) initn: 821 init1: 559 opt: 1121 Z-score: 922.1 bits: 178.6 E(85289): 1.3e-44 Smith-Waterman score: 1121; 67.2% identity (83.6% similar) in 250 aa overlap (37-285:61-304) 10 20 30 40 50 60 pF1KE0 VNSTAAAAAGQPNVSCTCNCKRSLFQSMEITELEFVQIIIIVVVMMVMVVVITCLLSHYK .::::.::::::::. ::::::.:::.::: NP_852 VCNQQNDCGDNSDEENCLLVTEHPPPGIFNSELEFAQIIIIVVVVTVMVVVIVCLLNHYK 40 50 60 70 80 90 70 80 90 100 110 120 pF1KE0 LSARSFISRHSQGRRREDALSSEGCLWPSESTVSGNGIPEPQVYAPPRPTDRLAVPPFAQ .:.::::.: .:.:::::.: .:::::::.:.. : : .. :: ::...: : : NP_852 VSTRSFINRPNQSRRREDGLPQEGCLWPSDSAAPRLGASE--IMHAPRSRDRFTAPSFIQ 100 110 120 130 140 130 140 150 160 170 180 pF1KE0 RERFHRFQPTYPYLQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNRESVRAP :.:: ::::::::.:::::::::::::::::::::::::::::::::::.:::::::::: NP_852 RDRFSRFQPTYPYVQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQMELNRESVRAP 150 160 170 180 190 200 190 200 210 220 230 240 pF1KE0 PNRTIFDSDLMDSARL-GGPCPPSSNSGISATCYGSGGRMEGPPPTYSEVIGHYPGSSFQ ::::::::::.: : ::::::::::::::. .:.:::::::::::::.::.::.:: NP_852 PNRTIFDSDLIDIAMYSGGPCPPSSNSGISASTCSSNGRMEGPPPTYSEVMGHHPGASFL 210 220 230 240 250 260 250 260 270 280 pF1KE0 HQQSSGPPSLLEGTRLHHTHIAPLESAAIWSKEKDKQKGHPL :.: :. .:.::. . ::. . : ::.. :. NP_852 HHQRSNAH---RGSRLQFQQ-NNAESTIVPIKGKDRKPGNLV 270 280 290 300 >>XP_005258197 (OMIM: 606571) PREDICTED: low-density lip (306 aa) initn: 821 init1: 559 opt: 1121 Z-score: 922.1 bits: 178.6 E(85289): 1.3e-44 Smith-Waterman score: 1121; 67.2% identity (83.6% similar) in 250 aa overlap (37-285:61-304) 10 20 30 40 50 60 pF1KE0 VNSTAAAAAGQPNVSCTCNCKRSLFQSMEITELEFVQIIIIVVVMMVMVVVITCLLSHYK .::::.::::::::. ::::::.:::.::: XP_005 VCNQQNDCGDNSDEENCLLVTEHPPPGIFNSELEFAQIIIIVVVVTVMVVVIVCLLNHYK 40 50 60 70 80 90 70 80 90 100 110 120 pF1KE0 LSARSFISRHSQGRRREDALSSEGCLWPSESTVSGNGIPEPQVYAPPRPTDRLAVPPFAQ .:.::::.: .:.:::::.: .:::::::.:.. : : .. :: ::...: : : XP_005 VSTRSFINRPNQSRRREDGLPQEGCLWPSDSAAPRLGASE--IMHAPRSRDRFTAPSFIQ 100 110 120 130 140 130 140 150 160 170 180 pF1KE0 RERFHRFQPTYPYLQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNRESVRAP :.:: ::::::::.:::::::::::::::::::::::::::::::::::.:::::::::: XP_005 RDRFSRFQPTYPYVQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQMELNRESVRAP 150 160 170 180 190 200 190 200 210 220 230 240 pF1KE0 PNRTIFDSDLMDSARL-GGPCPPSSNSGISATCYGSGGRMEGPPPTYSEVIGHYPGSSFQ ::::::::::.: : ::::::::::::::. .:.:::::::::::::.::.::.:: XP_005 PNRTIFDSDLIDIAMYSGGPCPPSSNSGISASTCSSNGRMEGPPPTYSEVMGHHPGASFL 210 220 230 240 250 260 250 260 270 280 pF1KE0 HQQSSGPPSLLEGTRLHHTHIAPLESAAIWSKEKDKQKGHPL :.: :. .:.::. . ::. . : ::.. :. XP_005 HHQRSNAH---RGSRLQFQQ-NNAESTIVPIKGKDRKPGNLV 270 280 290 300 287 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:29:36 2016 done: Sat Nov 5 04:29:37 2016 Total Scan time: 8.580 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]