Result of FASTA (ccds) for
pF1KE0920
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0920, 313 aa
1>>>pF1KE0920 313 - 313 aa - 313 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.0684+/-0.00106; mu= -4.8816+/- 0.061
mean_var=229.9862+/-53.885, 0's: 0 Z-trim(109.5): 519 B-trim: 344 in 1/52
Lambda= 0.084571
statistics sampled from 10251 (10904) to 10251 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.711), E-opt: 0.2 (0.335), width: 16
Scan time: 2.720
The best scores are: opt bits E(32554)
CCDS4830.1 PIM1 gene_id:5292|Hs108|chr6 ( 313) 2158 276.5 1.8e-74
CCDS33678.1 PIM3 gene_id:415116|Hs108|chr22 ( 326) 1491 195.2 5.9e-50
CCDS14312.1 PIM2 gene_id:11040|Hs108|chrX ( 311) 1146 153.1 2.7e-37
CCDS1453.2 NUAK2 gene_id:81788|Hs108|chr1 ( 672) 510 75.7 1.1e-13
CCDS31892.1 NUAK1 gene_id:9891|Hs108|chr12 ( 661) 504 75.0 1.8e-13
CCDS12921.1 BRSK1 gene_id:84446|Hs108|chr19 ( 778) 488 73.1 8e-13
CCDS8347.1 SIK2 gene_id:23235|Hs108|chr11 ( 926) 478 71.9 2.1e-12
CCDS33575.1 SIK1 gene_id:150094|Hs108|chr21 ( 783) 476 71.6 2.2e-12
CCDS82645.1 LOC102724428 gene_id:102724428|Hs108|c ( 783) 476 71.6 2.2e-12
CCDS41590.1 BRSK2 gene_id:9024|Hs108|chr11 ( 668) 472 71.1 2.7e-12
CCDS58106.1 BRSK2 gene_id:9024|Hs108|chr11 ( 674) 472 71.1 2.8e-12
CCDS2545.1 PASK gene_id:23178|Hs108|chr2 (1323) 478 72.0 2.8e-12
CCDS58107.1 BRSK2 gene_id:9024|Hs108|chr11 ( 736) 472 71.1 3e-12
CCDS53651.1 MARK2 gene_id:2011|Hs108|chr11 ( 709) 457 69.3 1e-11
CCDS53650.1 MARK2 gene_id:2011|Hs108|chr11 ( 719) 457 69.3 1e-11
CCDS8051.2 MARK2 gene_id:2011|Hs108|chr11 ( 724) 457 69.3 1e-11
CCDS53649.1 MARK2 gene_id:2011|Hs108|chr11 ( 788) 457 69.3 1.1e-11
CCDS59123.1 MELK gene_id:9833|Hs108|chr9 ( 610) 454 68.8 1.2e-11
CCDS6606.1 MELK gene_id:9833|Hs108|chr9 ( 651) 454 68.9 1.2e-11
CCDS58759.1 PASK gene_id:23178|Hs108|chr2 (1330) 458 69.6 1.5e-11
CCDS43075.1 SNRK gene_id:54861|Hs108|chr3 ( 765) 452 68.7 1.7e-11
CCDS12658.1 MARK4 gene_id:57787|Hs108|chr19 ( 688) 448 68.2 2.1e-11
CCDS56097.1 MARK4 gene_id:57787|Hs108|chr19 ( 752) 448 68.2 2.3e-11
CCDS41665.1 MARK2 gene_id:2011|Hs108|chr11 ( 745) 443 67.6 3.5e-11
CCDS58108.1 BRSK2 gene_id:9024|Hs108|chr11 ( 766) 441 67.3 4.2e-11
CCDS362.1 TSSK3 gene_id:81629|Hs108|chr1 ( 268) 427 65.3 6.1e-11
CCDS55947.1 MARK3 gene_id:4140|Hs108|chr14 ( 713) 435 66.6 6.6e-11
CCDS41993.1 MARK3 gene_id:4140|Hs108|chr14 ( 729) 435 66.6 6.7e-11
CCDS45166.1 MARK3 gene_id:4140|Hs108|chr14 ( 744) 435 66.6 6.8e-11
CCDS45165.1 MARK3 gene_id:4140|Hs108|chr14 ( 753) 435 66.6 6.9e-11
CCDS73034.1 MARK1 gene_id:4139|Hs108|chr1 ( 780) 434 66.5 7.7e-11
CCDS31029.2 MARK1 gene_id:4139|Hs108|chr1 ( 795) 434 66.5 7.8e-11
CCDS73033.1 MARK1 gene_id:4139|Hs108|chr1 ( 796) 434 66.5 7.8e-11
CCDS60974.1 SIK3 gene_id:23387|Hs108|chr11 (1261) 438 67.1 7.9e-11
CCDS8379.2 SIK3 gene_id:23387|Hs108|chr11 (1321) 438 67.2 8.2e-11
>>CCDS4830.1 PIM1 gene_id:5292|Hs108|chr6 (313 aa)
initn: 2158 init1: 2158 opt: 2158 Z-score: 1450.4 bits: 276.5 E(32554): 1.8e-74
Smith-Waterman score: 2158; 100.0% identity (100.0% similar) in 313 aa overlap (1-313:1-313)
10 20 30 40 50 60
pF1KE0 MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLIL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 ERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 ELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 PFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 PFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETA
250 260 270 280 290 300
310
pF1KE0 EIHLHSLSPGPSK
:::::::::::::
CCDS48 EIHLHSLSPGPSK
310
>>CCDS33678.1 PIM3 gene_id:415116|Hs108|chr22 (326 aa)
initn: 1466 init1: 1155 opt: 1491 Z-score: 1010.3 bits: 195.2 E(32554): 5.9e-50
Smith-Waterman score: 1491; 69.5% identity (87.3% similar) in 315 aa overlap (1-309:1-313)
10 20 30 40 50
pF1KE0 MLLSKINSLAHLRAAPCNDLHATK-LAPGK-EKEPLESQYQVGPLLGSGGFGSVYSGIRV
:::::..::::: . : .: : :.: .:: .:. :::: .:::::::.::.: :.
CCDS33 MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 SDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSS--GFSGVIRLLDWFERPDSF
.:.::::.::: :.:...:: : .:. ::.:::::.::.. : :::::::::::::.:
CCDS33 ADGLPVAVKHVVKERVTEWGSL-GGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGF
70 80 90 100 110
120 130 140 150 160 170
pF1KE0 VLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILID
.:.::::::.:::::::::::::.: ::: :: ::: ::::::.:::.::::::::.:.:
CCDS33 LLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVD
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 LNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMV
: ::::::::::::::::::::::::::::::::::::::::::::.:::::.::::::
CCDS33 LRSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 CGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWM--QDVL
:::::::.::::.::...::.::: :::.::::::.::::.::....: :::: :
CCDS33 CGDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWMLGADGG
240 250 260 270 280 290
300 310
pF1KE0 LPQETAEIHLHSLSPGPSK
.: :. ...: .:.:
CCDS33 VP-ESCDLRLCTLDPDDVASTTSSSESL
300 310 320
>>CCDS14312.1 PIM2 gene_id:11040|Hs108|chrX (311 aa)
initn: 1143 init1: 907 opt: 1146 Z-score: 783.1 bits: 153.1 E(32554): 2.7e-37
Smith-Waterman score: 1146; 56.3% identity (77.2% similar) in 302 aa overlap (12-311:6-304)
10 20 30 40 50 60
pF1KE0 MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSD
:.. : : ::..: .:..:..:::::.::::.:..: :..:
CCDS14 MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRLTD
10 20 30 40 50
70 80 90 100 110
pF1KE0 NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSG--FSGVIRLLDWFERPDSFVL
: :::: . ..:. :. : ... :.::.:: ::..: :::::::::: ..:.:
CCDS14 RLQVAIKVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFML
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 ILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLN
.:::: :.:::::.:::.: : : .: :: ::. :..:::. ::.:::::::::::::
CCDS14 VLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 RGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCG
:: :::::::::::.: :::::::::::::::: :.::. :.::::::::::::::
CCDS14 RGCAKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 DIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQE
:::::.:.::..... : .:: .: ::: ::: .::.::..::: :::: : :
CCDS14 DIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQT---PAE
240 250 260 270 280 290
300 310
pF1KE0 TAEIHLHSLSPGPSK
. .. . .:.:
CCDS14 DVPLNPSKGGPAPLAWSLLP
300 310
>>CCDS1453.2 NUAK2 gene_id:81788|Hs108|chr1 (672 aa)
initn: 393 init1: 277 opt: 510 Z-score: 359.1 bits: 75.7 E(32554): 1.1e-13
Smith-Waterman score: 510; 36.0% identity (65.2% similar) in 267 aa overlap (31-290:90-347)
10 20 30 40 50 60
pF1KE0 MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSD
:. :. .:. ::.: .:.: .. . :
CCDS14 AAELARPLAEGLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVKKARESSG
60 70 80 90 100 110
70 80 90 100 110 120
pF1KE0 NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLIL
: :::: ..::.:.: .: . : :. ...... .: . . :: ...:...
CCDS14 RL-VAIKSIRKDKIKDEQDLMHIRR---EIEIMSSLN--HPHIIAIHEVFENSSKIVIVM
120 130 140 150 160 170
130 140 150 160 170 180
pF1KE0 ERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRG
: ::.:.:.:: :.:. :: :: :.. ::..::. :.:::.: ::::.: : :
CCDS14 EYASR-GDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDAN-G
180 190 200 210 220 230
190 200 210 220 230
pF1KE0 ELKLIDFGSGALLKDTVYTD-FDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGD
..:. ::: . : .. . . : :. .:. :: . . : : . ::::.::: .: :
CCDS14 NIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLLYILVHGT
240 250 260 270 280 290
240 250 260 270 280 290
pF1KE0 IPFE-HDEEIIRGQVF---FRQ--RVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDV
.::. ::..:. :. .:. . :. : :::: : . :. : :.:.. .: :.
CCDS14 MPFDGHDHKILVKQISNGAYREPPKPSDACG-LIRWLLMVNPTRRATLEDVASHWWVNWG
300 310 320 330 340 350
300 310
pF1KE0 LLPQETAEIHLHSLSPGPSK
CCDS14 YATRVGEQEAPHEGGHPGSDSARASMADWLRRSSRPLLENGAKVCSFFKQHAPGGGSTTP
360 370 380 390 400 410
>>CCDS31892.1 NUAK1 gene_id:9891|Hs108|chr12 (661 aa)
initn: 418 init1: 256 opt: 504 Z-score: 355.3 bits: 75.0 E(32554): 1.8e-13
Smith-Waterman score: 504; 35.0% identity (64.7% similar) in 266 aa overlap (31-290:48-306)
10 20 30 40 50 60
pF1KE0 MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSD
:. :. .:.. ::.: .:.: . . .
CCDS31 GAPGSPREAVAGATAALEPRKPHGVKRHHHKHNLKHRYELQETLGKGTYGKVKRATERFS
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE0 NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLIL
. :::: ..::.:.: .. . : :. ...... .: . . :: :..:.:.
CCDS31 GRVVAIKSIRKDKIKDEQDMVHIRR---EIEIMSSLN--HPHIISIYEVFENKDKIVIIM
80 90 100 110 120 130
130 140 150 160 170 180
pF1KE0 ERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRG
: .:.:.:.:: :.:. .: :: :.. ::..::. ::.:::.: ::::.: :
CCDS31 EYASK-GELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDN-C
140 150 160 170 180 190
190 200 210 220 230
pF1KE0 ELKLIDFGSGALL-KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGD
..:. ::: . : :: : :. .:. :: . . :.: . :.::.::: .: :
CCDS31 NIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLVYGT
200 210 220 230 240 250
240 250 260 270 280 290
pF1KE0 IPFE-HDEEIIRGQVF---FRQRVS-SECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVL
.::. :.. . :. .:. .. :. . :::: : . :. : :.:.: :: :.
CCDS31 MPFDGFDHKNLIRQISSGEYREPTQPSDARGLIRWMLMVNPDRRATIEDIANHWWVNWGY
260 270 280 290 300 310
300 310
pF1KE0 LPQETAEIHLHSLSPGPSK
CCDS31 KSSVCDCDALHDSESPLLARIIDWHHRSTGLQADTEAKMKGLAKPTTSEVMLERQRSLKK
320 330 340 350 360 370
>>CCDS12921.1 BRSK1 gene_id:84446|Hs108|chr19 (778 aa)
initn: 362 init1: 260 opt: 488 Z-score: 343.7 bits: 73.1 E(32554): 8e-13
Smith-Waterman score: 488; 31.8% identity (61.4% similar) in 280 aa overlap (22-289:14-284)
10 20 30 40 50
pF1KE0 MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPL-----LGSGGFGSVYSG
: .: . . : ..:: ::: ::.: : : :
CCDS12 MSSGAKEGGGGSPAYHLPHPHPHPPQHAQY-VGPYRLEKTLGKGQTGLVKLG
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 IRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDS
.. . :::: :.....:. . .: :...:: . :..: : .:
CCDS12 VHCITGQKVAIKIVNREKLSESVLM----KVEREIAILKLIEHPH--VLKLHDVYENKKY
60 70 80 90 100
120 130 140 150 160 170
pF1KE0 FVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILI
. :.::. .:::.....: : . ::.:: :.. :. ::. .. :::.: ::.:.
CCDS12 LYLVLEHVSG-GELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLL
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE0 DLNRGELKLIDFGSGAL-LKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYD
: ....... ::: ..: . :.. :. :. :: :. ..: :: : .:: :..:.
CCDS12 D-EKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFA
170 180 190 200 210 220
240 250 260 270 280
pF1KE0 MVCGDIPFEHD------EEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHP
.. : .::. : :.. :: . . . .:: :.: . ..: : ..:.::.::
CCDS12 LLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHP
230 240 250 260 270 280
290 300 310
pF1KE0 WMQDVLLPQETAEIHLHSLSPGPSK
:
CCDS12 WYLGGKHEPDPCLEPAPGRRVAMRSLPSNGELDPDVLESMASLGCFRDRERLHRELRSEE
290 300 310 320 330 340
>>CCDS8347.1 SIK2 gene_id:23235|Hs108|chr11 (926 aa)
initn: 364 init1: 265 opt: 478 Z-score: 336.1 bits: 71.9 E(32554): 2.1e-12
Smith-Waterman score: 486; 33.8% identity (62.5% similar) in 275 aa overlap (38-298:20-286)
10 20 30 40 50 60
pF1KE0 SLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIK
:.. ::.:.:. : : . . ::::
CCDS83 MVMADGPRHLQRGPVRVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIK
10 20 30 40
70 80 90 100 110 120
pF1KE0 HVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQ
..:... . : .. :: ..: .. .:.: . .: . . :. : .
CCDS83 IIDKSQL----DAVNLEKIYREVQIMKMLD--HPHIIKLYQVMETKSMLYLVTEYAKN-G
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 DLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDF
..::.....: :.: :: :::.: :: .::. ..:::.: ::.:.: : ..:. ::
CCDS83 EIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLD-NNMNIKIADF
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE0 GSGALLKD-TVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDE
: : ..:. . . . :. :. :: .. ..:.: . .::.:..:: .::: .::.
CCDS83 GFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPT
170 180 190 200 210 220
250 260 270 280 290
pF1KE0 -EIIRGQVF---FR--QRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWM-------QDV
:.: .:. :: .: .:.:::: :.: :: : :. .:..: :: . :
CCDS83 LPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQIKEHKWMLIEVPVQRPV
230 240 250 260 270 280
300 310
pF1KE0 LLPQETAEIHLHSLSPGPSK
: :::
CCDS83 LYPQEQENEPSIGEFNEQVLRLMHSLGIDQQKTIESLQNKSYNHFAAIYFLLVERLKSHR
290 300 310 320 330 340
>>CCDS33575.1 SIK1 gene_id:150094|Hs108|chr21 (783 aa)
initn: 303 init1: 273 opt: 476 Z-score: 335.8 bits: 71.6 E(32554): 2.2e-12
Smith-Waterman score: 476; 32.7% identity (64.0% similar) in 272 aa overlap (28-291:17-279)
10 20 30 40 50
pF1KE0 MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQ-YQVGPLLGSGGFGSVYSGIRVS
:..: ::. :.. ::.:.:. : . .
CCDS33 MVIMSEFSADPAGQGQGQQK-PLRVGFYDIERTLGKGNFAVVKLARHRV
10 20 30 40
60 70 80 90 100 110
pF1KE0 DNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLI
. :::: ..: :... : .. :: :.: .. .:.: . .: : . ..
CCDS33 TKTQVAIKIIDKTRLDS----SNLEKIYREVQLMKLLN--HPHIIKLYQVMETKDMLYIV
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE0 LERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNR
: . ..::..: : :.:. ::. :::.: ::..::. ..:::.: ::.:.: :
CCDS33 TEFAKN-GEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNM
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE0 GELKLIDFGSGALLKD-TVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCG
..:: ::: : . :. . . :. :. :: .. ..:.: . .::::..:: .:::
CCDS33 -DIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCG
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE0 DIPFEHD------EEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQD
..::. .....:. . .:..:. ::: :.. :. : :. .:..: ::.
CCDS33 SLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLVVDPARRITIAQIRQHRWMRA
230 240 250 260 270 280
300 310
pF1KE0 VLLPQETAEIHLHSLSPGPSK
CCDS33 EPCLPGPACPAFSAHSYTSNLGDYDEQALGIMQTLGVDRQRTVESLQNSSYNHFAAIYYL
290 300 310 320 330 340
>>CCDS82645.1 LOC102724428 gene_id:102724428|Hs108|chr21 (783 aa)
initn: 303 init1: 273 opt: 476 Z-score: 335.8 bits: 71.6 E(32554): 2.2e-12
Smith-Waterman score: 476; 32.7% identity (64.0% similar) in 272 aa overlap (28-291:17-279)
10 20 30 40 50
pF1KE0 MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQ-YQVGPLLGSGGFGSVYSGIRVS
:..: ::. :.. ::.:.:. : . .
CCDS82 MVIMSEFSADPAGQGQGQQK-PLRVGFYDIERTLGKGNFAVVKLARHRV
10 20 30 40
60 70 80 90 100 110
pF1KE0 DNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLI
. :::: ..: :... : .. :: :.: .. .:.: . .: : . ..
CCDS82 TKTQVAIKIIDKTRLDS----SNLEKIYREVQLMKLLN--HPHIIKLYQVMETKDMLYIV
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE0 LERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNR
: . ..::..: : :.:. ::. :::.: ::..::. ..:::.: ::.:.: :
CCDS82 TEFAKN-GEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNM
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE0 GELKLIDFGSGALLKD-TVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCG
..:: ::: : . :. . . :. :. :: .. ..:.: . .::::..:: .:::
CCDS82 -DIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCG
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE0 DIPFEHD------EEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQD
..::. .....:. . .:..:. ::: :.. :. : :. .:..: ::.
CCDS82 SLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLVVDPARRITIAQIRQHRWMRA
230 240 250 260 270 280
300 310
pF1KE0 VLLPQETAEIHLHSLSPGPSK
CCDS82 EPCLPGPACPAFSAHSYTSNLGDYDEQALGIMQTLGVDRQRTVESLQNSSYNHFAAIYYL
290 300 310 320 330 340
>>CCDS41590.1 BRSK2 gene_id:9024|Hs108|chr11 (668 aa)
initn: 340 init1: 270 opt: 472 Z-score: 334.1 bits: 71.1 E(32554): 2.7e-12
Smith-Waterman score: 472; 32.5% identity (60.9% similar) in 274 aa overlap (28-289:5-269)
10 20 30 40 50
pF1KE0 MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPL-----LGSGGFGSVYSG
::. ..:: ::: ::.: : : :
CCDS41 MTSTGKDGGAQHAQY-VGPYRLEKTLGKGQTGLVKLG
10 20 30
60 70 80 90 100 110
pF1KE0 IRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDS
.. :::: :.....:. . .: :...:: . :..: : .:
CCDS41 VHCVTCQKVAIKIVNREKLSESVLM----KVEREIAILKLIEHPH--VLKLHDVYENKKY
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE0 FVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILI
. :.::. .:::.....: : . ::.:: :.. :. ::. .. :::.: ::.:.
CCDS41 LYLVLEHVSG-GELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLL
100 110 120 130 140
180 190 200 210 220 230
pF1KE0 DLNRGELKLIDFGSGAL-LKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYD
: ....... ::: ..: . :.. :. :. :: :: ..: ::.: ::: :..:.
CCDS41 D-EKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFA
150 160 170 180 190 200
240 250 260 270 280
pF1KE0 MVCGDIPFEHD------EEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHP
.. : .::. : :.. :: . . . .:: :.: . . . : :.:.::.:
CCDS41 LLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHI
210 220 230 240 250 260
290 300 310
pF1KE0 WMQDVLLPQETAEIHLHSLSPGPSK
:
CCDS41 WYIGGKNEPEPEQPIPRKVQIRSLPSLEDIDPDVLDSMHSLGCFRDRNKLLQDLLSEEEN
270 280 290 300 310 320
313 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 04:30:46 2016 done: Sat Nov 5 04:30:46 2016
Total Scan time: 2.720 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]