FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0921, 282 aa
  1>>>pF1KE0921 282 - 282 aa - 282 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3341+/-0.000912; mu= 17.4869+/- 0.055
 mean_var=115.6554+/-23.168, 0's: 0 Z-trim(110.1): 53  B-trim: 0 in 0/52
 Lambda= 0.119259
 statistics sampled from 11319 (11367) to 11319 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.349), width:  16
 Scan time:  2.320

The best scores are:                                      opt bits E(32554)
CCDS10735.1 SIAH1 gene_id:6477|Hs108|chr16         ( 282) 1978 350.8 6.6e-97
CCDS32444.1 SIAH1 gene_id:6477|Hs108|chr16         ( 313) 1978 350.8 7.1e-97
CCDS3152.1 SIAH2 gene_id:6478|Hs108|chr3           ( 324) 1552 277.5 8.4e-75
CCDS41883.1 SIAH3 gene_id:283514|Hs108|chr13       ( 269)  636 119.8 2.1e-27


>>CCDS10735.1 SIAH1 gene_id:6477|Hs108|chr16              (282 aa)
 initn: 1978 init1: 1978 opt: 1978  Z-score: 1853.2  bits: 350.8 E(32554): 6.6e-97
Smith-Waterman score: 1978; 100.0% identity (100.0% similar) in 282 aa overlap (1-282:1-282)

               10        20        30        40        50        60
pF1KE0 MSRQTATALPTGTSKCPPSQRVPALTGTTASNNDLASLFECPVCFDYVLPPILQCQSGHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MSRQTATALPTGTSKCPPSQRVPALTGTTASNNDLASLFECPVCFDYVLPPILQCQSGHL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 VCSNCRPKLTCCPTCRGPLGSIRNLAMEKVANSVLFPCKYASSGCEITLPHTEKADHEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 VCSNCRPKLTCCPTCRGPLGSIRNLAMEKVANSVLFPCKYASSGCEITLPHTEKADHEEL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 CEFRPYSCPCPGASCKWQGSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 CEFRPYSCPCPGASCKWQGSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 MQSCFGFHFMLVLEKQEKYDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MQSCFGFHFMLVLEKQEKYDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATP
              190       200       210       220       230       240

              250       260       270       280  
pF1KE0 RSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISMC
       ::::::::::::::::::::::::::::::::::::::::::
CCDS10 RSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISMC
              250       260       270       280  

>>CCDS32444.1 SIAH1 gene_id:6477|Hs108|chr16              (313 aa)
 initn: 1978 init1: 1978 opt: 1978  Z-score: 1852.7  bits: 350.8 E(32554): 7.1e-97
Smith-Waterman score: 1978; 100.0% identity (100.0% similar) in 282 aa overlap (1-282:32-313)

                                             10        20        30
pF1KE0                               MSRQTATALPTGTSKCPPSQRVPALTGTTA
                                     ::::::::::::::::::::::::::::::
CCDS32 TGKATPPSLYSWRGVLFTCLPAARTRKRKEMSRQTATALPTGTSKCPPSQRVPALTGTTA
              10        20        30        40        50        60 

               40        50        60        70        80        90
pF1KE0 SNNDLASLFECPVCFDYVLPPILQCQSGHLVCSNCRPKLTCCPTCRGPLGSIRNLAMEKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 SNNDLASLFECPVCFDYVLPPILQCQSGHLVCSNCRPKLTCCPTCRGPLGSIRNLAMEKV
              70        80        90       100       110       120 

              100       110       120       130       140       150
pF1KE0 ANSVLFPCKYASSGCEITLPHTEKADHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLMH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 ANSVLFPCKYASSGCEITLPHTEKADHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLMH
             130       140       150       160       170       180 

              160       170       180       190       200       210
pF1KE0 QHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFFAIVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 QHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFFAIVQ
             190       200       210       220       230       240 

              220       230       240       250       260       270
pF1KE0 LIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 LIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAEN
             250       260       270       280       290       300 

              280  
pF1KE0 GNLGINVTISMC
       ::::::::::::
CCDS32 GNLGINVTISMC
             310   

>>CCDS3152.1 SIAH2 gene_id:6478|Hs108|chr3                (324 aa)
 initn: 1563 init1: 1243 opt: 1552  Z-score: 1456.4  bits: 277.5 E(32554): 8.4e-75
Smith-Waterman score: 1552; 77.6% identity (89.2% similar) in 286 aa overlap (5-282:37-322)

                                         10        20              
pF1KE0                           MSRQTATALPTGTSKCPPSQRV---PALTG----
                                     : .:   :.:  : .  :   :.  :    
CCDS31 TGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGP
         10        20        30        40        50        60      

        30        40        50        60        70        80       
pF1KE0 TTASNNDLASLFECPVCFDYVLPPILQCQSGHLVCSNCRPKLTCCPTCRGPLG-SIRNLA
       .. ....:.::::::::::::::::::::.:::::..:: ::.::::::: :  ::::::
CCDS31 VSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLA
         70        80        90       100       110       120      

         90       100       110       120       130       140      
pF1KE0 MEKVANSVLFPCKYASSGCEITLPHTEKADHEELCEFRPYSCPCPGASCKWQGSLDAVMP
       :::::..::::::::..:: .:: :::: .::..::.::::::::::::::::::.::: 
CCDS31 MEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMS
        130       140       150       160       170       180      

        150       160       170       180       190       200      
pF1KE0 HLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFF
       :::: ::::::::::::::::::::::::::::::::::: ::::::::::::.::::::
CCDS31 HLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFF
        190       200       210       220       230       240      

        210       220       230       240       250       260      
pF1KE0 AIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQL
       ::: :::::::::::::::::::.::::::::::::::.:.:.::::::::::::.::.:
CCDS31 AIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHL
        250       260       270       280       290       300      

        270       280    
pF1KE0 FAENGNLGINVTISMC  
       ::.::::::::::: :  
CCDS31 FADNGNLGINVTISTCCP
        310       320    

>>CCDS41883.1 SIAH3 gene_id:283514|Hs108|chr13            (269 aa)
 initn: 623 init1: 520 opt: 636  Z-score: 605.6  bits: 119.8 E(32554): 2.1e-27
Smith-Waterman score: 636; 52.3% identity (79.7% similar) in 172 aa overlap (109-280:90-258)

       80        90       100       110       120       130        
pF1KE0 LGSIRNLAMEKVANSVLFPCKYASSGCEITLPHTEKADHEELCEFRPYSCPCPGASCKWQ
                                     : : : . : .     :  : ::  ::.:.
CCDS41 QGSFHPHHLSHHHCHHRHHHHLRHHAHPHHLHHQEAGLHAN--PVTPCLCMCPLFSCQWE
      60        70        80        90       100         110       

      140       150       160       170       180       190        
pF1KE0 GSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEK
       : :..:.::: . :. .  ::: .:::::::..::. .::..:.::.: ::.:::.:::.
CCDS41 GRLEVVVPHLRQIHR-VDILQGAEIVFLATDMHLPAPADWIIMHSCLGHHFLLVLRKQER
       120       130        140       150       160       170      

      200       210       220       230       240       250        
pF1KE0 YDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLV
       ..:: :::: ..::::  ::. :.:::::: ..::: :::::::. : . ..: ..::::
CCDS41 HEGHPQFFATMMLIGTPTQADCFTYRLELNRNHRRLKWEATPRSVLECVDSVITDGDCLV
        180       190       200       210       220       230      

      260       270       280           
pF1KE0 FDTSIAQLFAENGNLGINVTISMC         
       ..::.::::..::.:.:...:.           
CCDS41 LNTSLAQLFSDNGSLAIGIAITATEVLPSEAEM
        240       250       260         




282 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 07:36:04 2016 done: Sat Nov  5 07:36:05 2016
 Total Scan time:  2.320 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]