FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0924, 343 aa 1>>>pF1KE0924 343 - 343 aa - 343 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4162+/-0.000781; mu= 14.1448+/- 0.047 mean_var=174.1678+/-35.847, 0's: 0 Z-trim(114.4): 181 B-trim: 0 in 0/53 Lambda= 0.097183 statistics sampled from 14723 (14940) to 14723 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.792), E-opt: 0.2 (0.459), width: 16 Scan time: 3.010 The best scores are: opt bits E(32554) CCDS5797.1 PAX4 gene_id:5078|Hs108|chr7 ( 343) 2389 346.5 1.9e-95 CCDS31451.1 PAX6 gene_id:5080|Hs108|chr11 ( 422) 630 100.0 3.7e-21 CCDS65043.1 PAX5 gene_id:5079|Hs108|chr9 ( 348) 586 93.7 2.4e-19 CCDS46399.1 PAX8 gene_id:7849|Hs108|chr2 ( 398) 586 93.8 2.6e-19 CCDS65042.1 PAX5 gene_id:5079|Hs108|chr9 ( 319) 582 93.1 3.3e-19 CCDS42735.1 PAX8 gene_id:7849|Hs108|chr2 ( 287) 566 90.8 1.5e-18 CCDS41561.1 PAX2 gene_id:5076|Hs108|chr10 ( 394) 565 90.9 2e-18 CCDS7499.1 PAX2 gene_id:5076|Hs108|chr10 ( 396) 565 90.9 2e-18 CCDS42736.1 PAX8 gene_id:7849|Hs108|chr2 ( 321) 558 89.8 3.4e-18 CCDS46398.1 PAX8 gene_id:7849|Hs108|chr2 ( 450) 558 89.9 4.2e-18 CCDS65044.1 PAX5 gene_id:5079|Hs108|chr9 ( 295) 552 88.9 5.8e-18 CCDS65045.1 PAX5 gene_id:5079|Hs108|chr9 ( 324) 551 88.8 6.8e-18 CCDS65046.1 PAX5 gene_id:5079|Hs108|chr9 ( 328) 542 87.5 1.6e-17 CCDS65047.1 PAX5 gene_id:5079|Hs108|chr9 ( 357) 542 87.6 1.7e-17 CCDS65048.1 PAX5 gene_id:5079|Hs108|chr9 ( 362) 542 87.6 1.7e-17 CCDS6607.1 PAX5 gene_id:5079|Hs108|chr9 ( 391) 542 87.6 1.8e-17 CCDS9662.1 PAX9 gene_id:5083|Hs108|chr14 ( 341) 483 79.3 5.2e-15 CCDS74709.1 PAX1 gene_id:5075|Hs108|chr20 ( 457) 480 79.0 8.3e-15 CCDS13146.2 PAX1 gene_id:5075|Hs108|chr20 ( 534) 480 79.1 9.2e-15 CCDS44075.1 PAX7 gene_id:5081|Hs108|chr1 ( 518) 470 77.7 2.4e-14 CCDS46522.1 PAX3 gene_id:5077|Hs108|chr2 ( 483) 468 77.4 2.8e-14 CCDS2451.1 PAX3 gene_id:5077|Hs108|chr2 ( 206) 453 74.8 7e-14 CCDS46523.1 PAX3 gene_id:5077|Hs108|chr2 ( 215) 453 74.8 7.2e-14 CCDS2450.1 PAX3 gene_id:5077|Hs108|chr2 ( 403) 456 75.6 7.9e-14 CCDS2449.1 PAX3 gene_id:5077|Hs108|chr2 ( 407) 456 75.6 8e-14 CCDS42826.1 PAX3 gene_id:5077|Hs108|chr2 ( 479) 456 75.7 8.8e-14 CCDS42825.1 PAX3 gene_id:5077|Hs108|chr2 ( 484) 456 75.7 8.9e-14 CCDS2448.1 PAX3 gene_id:5077|Hs108|chr2 ( 505) 456 75.7 9.1e-14 CCDS44074.1 PAX7 gene_id:5081|Hs108|chr1 ( 505) 449 74.7 1.8e-13 CCDS186.1 PAX7 gene_id:5081|Hs108|chr1 ( 520) 449 74.7 1.8e-13 CCDS31452.1 PAX6 gene_id:5080|Hs108|chr11 ( 436) 421 70.7 2.5e-12 >>CCDS5797.1 PAX4 gene_id:5078|Hs108|chr7 (343 aa) initn: 2389 init1: 2389 opt: 2389 Z-score: 1827.2 bits: 346.5 E(32554): 1.9e-95 Smith-Waterman score: 2389; 99.7% identity (99.7% similar) in 343 aa overlap (1-343:1-343) 10 20 30 40 50 60 pF1KE0 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRYYRTGVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS57 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRYYRTGVLE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSVSSINRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS57 PKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSVSSINRVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 RALQEDQGLPCTRLRSPAVLAPAVLTPHSGSETPRGTHPGTGHRNRTIFSPSQAEALEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS57 RALQEDQGLPCTRLRSPAVLAPAVLTPHSGSETPRGTHPGTGHRNRTIFSPSQAEALEKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 FQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGLTVPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS57 FQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGLTVPR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 VAPGIISAQQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACLKPCWGHLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS57 VAPGIISAQQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACLKPCWGHLP 250 260 270 280 290 300 310 320 330 340 pF1KE0 PQPNSLDSGLLCLPCPSSHCPLASLSGSQALLWPGCPLLYGLE :::::::::::::::::::: :::::::::::::::::::::: CCDS57 PQPNSLDSGLLCLPCPSSHCHLASLSGSQALLWPGCPLLYGLE 310 320 330 340 >>CCDS31451.1 PAX6 gene_id:5080|Hs108|chr11 (422 aa) initn: 935 init1: 618 opt: 630 Z-score: 493.3 bits: 100.0 E(32554): 3.7e-21 Smith-Waterman score: 821; 42.1% identity (60.7% similar) in 387 aa overlap (1-341:8-366) 10 20 30 40 50 pF1KE0 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRY .:::::.:::::::: .:::.::.:: :: :::::::::.::::::::::::: CCDS31 MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 YRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSV :.:: ..:..:::::::.::: ::..::: : :::..:::::. .: .::.::.:. ::: CCDS31 YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 70 80 90 100 110 120 120 130 140 150 160 pF1KE0 SSINRVLRAL-QEDQGLPCTRLRSPAVLAPAVLTPHSGSETPR-GTHPGTG--------- :::::::: : .: : . . . . :. ..:: : : .:::. CCDS31 SSINRVLRNLASEKQQMGADGMYDKLRM----LNGQTGSWGTRPGWYPGTSVPGQPTQDG 130 140 150 160 170 170 180 pF1KE0 ----------------------------------HRNRTIFSPSQAEALEKEFQRGQYPD .:::: :. : :::::::.: .::: CCDS31 CQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPD 180 190 200 210 220 230 190 200 210 220 230 240 pF1KE0 SVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGLTVPRVAPGIISA :: .::. .::: ..::::::::::::.:::. . . :. ..: : ::. CCDS31 VFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRR-----QASNTPSHIP--ISS 240 250 260 270 280 250 260 270 280 290 300 pF1KE0 QQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACLKPCWGHLPPQPN-SLD . : .. : .: : .... .:: : .. :::.:. .. CCDS31 SFS----TSVYQPIPQPTTPVS---SFTSGSMLGRTDTA----LTNTYSALPPMPSFTMA 290 300 310 320 330 310 320 330 340 pF1KE0 SGLLCLPCPSSHCPLASLSGSQALLWPGCPLLYGLE ..: : :. : ..: . . : : . : CCDS31 NNLPMQP------PVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTT 340 350 360 370 380 390 CCDS31 STGLISPGVSVPVQVPGSEPDMSQYWPRLQ 400 410 420 >>CCDS65043.1 PAX5 gene_id:5079|Hs108|chr9 (348 aa) initn: 578 init1: 531 opt: 586 Z-score: 460.9 bits: 93.7 E(32554): 2.4e-19 Smith-Waterman score: 586; 38.2% identity (61.8% similar) in 322 aa overlap (1-308:20-325) 10 20 30 40 pF1KE0 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKV .:::::.:::::::: .::.::.:: .:.::::::: :.: CCDS65 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 SNGCVSKILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCA :.:::::::::::.:: ..: ::::::..::: :: .::. : . :..:::::. .: : CCDS65 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLA 70 80 90 100 110 120 110 120 130 140 150 pF1KE0 EGLCTQDKTPSVSSINRVLRA-LQE--DQGLPCTRLRSPAVLAPAVLTPHS--GSETPRG : .: .: .::::::::..:. .:. .: .: . .: .. : . :: : . : CCDS65 ERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASS-HSIGIQESPVPNGHSLPGRDFLRK 130 140 150 160 170 160 170 180 190 200 210 pF1KE0 THPGTGHRNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAK : .:. .: :.:.. :.: .: : . .: ::.:.. .: . CCDS65 QMRGD------LFTQQQLEVLDRVFERQHYSDIFT----TTEPIKPEQTTE--YSAMASL 180 190 200 210 220 220 230 240 250 260 270 pF1KE0 WRRQEKLKWEMQLPG-ASQGLTVP--RVAPGIISAQQSPGSVPTAALPALEPLGPSCYQL . .: .. : :. : .:: . : . . . . ..: : . : : . :. CCDS65 AGGLDDMKANLASPTPADIGSSVPGPQSYPIVTGRDLASTTLPGYP-PHVPPAGQGSYSA 230 240 250 260 270 280 280 290 300 310 320 pF1KE0 CWATA--PERCLSDTP---PK-ACLKPCWGHLPPQPNSLDSGLLCLPCPSSHCPLASLSG :. : .: .: :. . . : :.:. : : CCDS65 PTLTGMVPGSEFSGSPYSHPQYSSYNDSWRF--PNPGLLGSPYYYSAAARGAAPPAAATA 290 300 310 320 330 340 330 340 pF1KE0 SQALLWPGCPLLYGLE CCDS65 YDRH >>CCDS46399.1 PAX8 gene_id:7849|Hs108|chr2 (398 aa) initn: 619 init1: 533 opt: 586 Z-score: 460.3 bits: 93.8 E(32554): 2.6e-19 Smith-Waterman score: 587; 36.8% identity (55.6% similar) in 383 aa overlap (1-321:13-385) 10 20 30 40 pF1KE0 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSK .::::: :::::::: .::.:: :: .:.::::::: :.::.::::: CCDS46 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 ILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQD ::::::.:: ..: ::::::..::: :: .:.. : . :..:::::. .: :::.: .: CCDS46 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND 70 80 90 100 110 120 110 120 130 140 150 pF1KE0 KTPSVSSINRVLRA-LQEDQGLP---C--TRLRSPA-VLAP--AVLTPHSGSETPRGT-- .::::::::..:. .:. .:: : :. ::. .: : :: :.: . :. CCDS46 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY 130 140 150 160 170 180 160 170 180 pF1KE0 ---------HPGTGHRN--------------------------RT-IFSPSQAEALEKEF .::. .:. :: :: . : :: : CCDS46 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF 190 200 210 220 230 240 190 200 210 220 230 pF1KE0 QRGQYPDSVARGKLATATS--LPEDTVRVWFSNRRAKWR-RQEKLKWEMQLPGASQGLTV .: .::.. : . . . . : . ... .: . : .. : : CCDS46 ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNL-----STHQTY 250 260 270 280 290 240 250 260 270 280 290 pF1KE0 PRVA--PGIISAQQSPGSVPTAALPALEP-LG-----PSCYQLCWATAPERCLSDTPPKA : :: : : ....::: :. .: : : : :: : .: :: :: : . CCDS46 PVVAAPPFWICSKSAPGSRPSMPFPMLPPCTGSSRARPSSQGERWW-GP-RC-PDTHPTS 300 310 320 330 340 350 300 310 320 330 340 pF1KE0 CLKPC-WGHLPPQPNSL---DSGLLCLPCPSSHCPLASLSGSQALLWPGCPLLYGLE : . .:: :.. . . : .: . : CCDS46 --PPADRAAMPPLPSQAWWQEVNTLAMPMATPPTPPTARPGASPTPAC 360 370 380 390 >>CCDS65042.1 PAX5 gene_id:5079|Hs108|chr9 (319 aa) initn: 557 init1: 531 opt: 582 Z-score: 458.3 bits: 93.1 E(32554): 3.3e-19 Smith-Waterman score: 582; 40.5% identity (64.5% similar) in 279 aa overlap (1-271:20-284) 10 20 30 40 pF1KE0 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKV .:::::.:::::::: .::.::.:: .:.::::::: :.: CCDS65 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 SNGCVSKILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCA :.:::::::::::.:: ..: ::::::..::: :: .::. : . :..:::::. .: : CCDS65 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLA 70 80 90 100 110 120 110 120 130 140 150 pF1KE0 EGLCTQDKTPSVSSINRVLRA-LQE--DQGLPCTRLRSPAVLAPAVLTPHS--GSETPRG : .: .: .::::::::..:. .:. .: .: . .: .. : . :: : . : CCDS65 ERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASS-HSIGIQESPVPNGHSLPGRDFLRK 130 140 150 160 170 160 170 180 190 200 210 pF1KE0 THPGTGHRNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAK : .:. .: :.:.. :.: .: : . .: ::.:.. .: . CCDS65 QMRGD------LFTQQQLEVLDRVFERQHYSDIFT----TTEPIKPEQTTE--YSAMASL 180 190 200 210 220 220 230 240 250 260 270 pF1KE0 WRRQEKLKWEMQLPG-ASQGLTVP--RVAPGIISAQQSPGSVPTAALPALEPLGPSCYQL . .: .. : :. : .:: . : . . . . ..: : . : : . : CCDS65 AGGLDDMKANLASPTPADIGSSVPGPQSYPIVTGRDLASTTLPGYP-PHVPPAGQGSYSA 230 240 250 260 270 280 280 290 300 310 320 330 pF1KE0 CWATAPERCLSDTPPKACLKPCWGHLPPQPNSLDSGLLCLPCPSSHCPLASLSGSQALLW CCDS65 PTLTGMVPGSPYYYSAAARGAAPPAAATAYDRH 290 300 310 >>CCDS42735.1 PAX8 gene_id:7849|Hs108|chr2 (287 aa) initn: 604 init1: 533 opt: 566 Z-score: 446.7 bits: 90.8 E(32554): 1.5e-18 Smith-Waterman score: 566; 39.1% identity (64.6% similar) in 274 aa overlap (1-268:13-274) 10 20 30 40 pF1KE0 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSK .::::: :::::::: .::.:: :: .:.::::::: :.::.::::: CCDS42 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 ILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQD ::::::.:: ..: ::::::..::: :: .:.. : . :..:::::. .: :::.: .: CCDS42 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 KTPSVSSINRVLRA-LQEDQGLPCTRLRSPAVLAPA-VLTPHSG---SETPRGTHPGTGH .::::::::..:. .:. .:: . :.:. .: : :. :.:.. :. . CCDS42 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE0 RNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRV-WFSNRRAKWRRQEK ... .: . ..... .. . ...: :. .:. :: :.. CCDS42 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFS--------QHH 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 LKWEMQLPGASQGLTVPRVAPGIISAQQSPGSVPTAALPALEPLGPSCYQLCWATAPERC :. .. : : ..:. ...: : : :.: : : CCDS42 LE-PLECPFERQHYPEAYASPSHTKGEQE---VNTLAMPMATPPTPPTARPGASPTPAC 240 250 260 270 280 290 300 310 320 330 340 pF1KE0 LSDTPPKACLKPCWGHLPPQPNSLDSGLLCLPCPSSHCPLASLSGSQALLWPGCPLLYGL >>CCDS41561.1 PAX2 gene_id:5076|Hs108|chr10 (394 aa) initn: 637 init1: 550 opt: 565 Z-score: 444.4 bits: 90.9 E(32554): 2e-18 Smith-Waterman score: 565; 39.6% identity (64.9% similar) in 285 aa overlap (1-280:20-291) 10 20 30 40 pF1KE0 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKV .:::::.:::::::: .::.::.:: .:.::::::: :.: CCDS41 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 SNGCVSKILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCA :.:::::::::::.:: ..: ::::::..::: :: .::. : . :..:::::. .: : CCDS41 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 EGLCTQDKTPSVSSINRVLRALQEDQGLPCTRLRSPAVLAPA-VLTPHSGSETPRGTHPG ::.: .: .::::::::..:. .. : . .: ::. ...: ..: : : CCDS41 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTAS--P----PV 130 140 150 160 170 170 180 190 200 210 pF1KE0 TGHRNRTIFSPSQAEAL---EKEFQRGQYPDSVARGKLATATSLPE-DTVRVWFSNRRAK .. : . : : : ... .. . ..:..:.. .. : :..: . CCDS41 SSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFT 180 190 200 210 220 230 220 230 240 250 260 270 pF1KE0 WRRQEKLKWEMQLPGASQGLTVPRVAPGIISAQQSPGSVPTAALPALEPLGPSCYQLCWA .. : : .. :. . : ... : : : . :.: : :.:. . : : . CCDS41 QQQLEALDRVFERPSYPD---VFQASEHIKSEQGNEYSLP-ALTPGLDEVKSS---LSAS 240 250 260 270 280 280 290 300 310 320 330 pF1KE0 TAPERCLSDTPPKACLKPCWGHLPPQPNSLDSGLLCLPCPSSHCPLASLSGSQALLWPGC : :: CCDS41 TNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGN 290 300 310 320 330 340 >>CCDS7499.1 PAX2 gene_id:5076|Hs108|chr10 (396 aa) initn: 658 init1: 550 opt: 565 Z-score: 444.4 bits: 90.9 E(32554): 2e-18 Smith-Waterman score: 596; 35.4% identity (58.6% similar) in 362 aa overlap (1-300:20-373) 10 20 30 40 pF1KE0 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKV .:::::.:::::::: .::.::.:: .:.::::::: :.: CCDS74 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 SNGCVSKILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCA :.:::::::::::.:: ..: ::::::..::: :: .::. : . :..:::::. .: : CCDS74 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 70 80 90 100 110 120 110 120 130 140 150 pF1KE0 EGLCTQDKTPSVSSINRVLRALQEDQGLPC-----TRLRSPA-VLAPAVLTP--HSGSET ::.: .: .::::::::..:. .. : : . .:. ...:.. .: :.:. CCDS74 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND 130 140 150 160 170 180 160 170 pF1KE0 PRGTHPGTG------------HRNRTI-------------------------FSPSQAEA : :.. .: .:.. . :. .: :: CCDS74 PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA 190 200 210 220 230 240 180 190 200 210 220 pF1KE0 LEKEFQRGQYPDSVA-----RGKLATATSLPE-----DTVRVWFSNRRAKWRRQEKLKWE :.. :.: .::: ... .. ::: : :. .: . ... CCDS74 LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNP-ELGSNVSGT 250 260 270 280 290 230 240 250 260 270 pF1KE0 MQLPGAS----QGLTVPRVAPGIISAQQSPGSVPTAALPALEP---LGPSCYQLCWATAP . : .. . :.: : . . : :: ::..: .. : .::: . . : CCDS74 QTYPVVTGRDMASTTLPGYPPHVPPTGQ--GSYPTSTLAGMVPEAAVGPSSSLM---SKP 300 310 320 330 340 350 280 290 300 310 320 330 pF1KE0 ERCLSDTPPKACLKPCWGHLPPQPNSLDSGLLCLPCPSSHCPLASLSGSQALLWPGCPLL : :...:: :..: . : CCDS74 GRKLAEVPP--CVQPTGASSPATRTATPSTRPTTRLGDSATPPY 360 370 380 390 >>CCDS42736.1 PAX8 gene_id:7849|Hs108|chr2 (321 aa) initn: 604 init1: 533 opt: 558 Z-score: 440.1 bits: 89.8 E(32554): 3.4e-18 Smith-Waterman score: 565; 38.3% identity (62.4% similar) in 303 aa overlap (1-290:13-311) 10 20 30 40 pF1KE0 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSK .::::: :::::::: .::.:: :: .:.::::::: :.::.::::: CCDS42 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 ILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQD ::::::.:: ..: ::::::..::: :: .:.. : . :..:::::. .: :::.: .: CCDS42 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 KTPSVSSINRVLRA-LQEDQGLPCTRLRSPAVLAPA-VLTPHSG---SETPRGTHPGTGH .::::::::..:. .:. .:: . :.:. .: : :. :.:.. :. . CCDS42 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY 130 140 150 160 170 180 170 180 190 200 210 pF1KE0 RNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRV-WFSNRRAK-----W ... .: . ..... .. . ...: :. .:. ::... . . CCDS42 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE0 RRQEKLKWEMQLPGASQGLTVPRVAPGIISAQQSPGSVPTAALPALEPLGPSC--YQLCW .::. . :. ..: : : . : : : : :. :: :: .: CCDS42 ERQH-YPEAYASPSHTKGEQGERWW-GPRCPDTHPTS-PPADRAAMPPL-PSQAWWQEVN 250 260 270 280 290 280 290 300 310 320 330 pF1KE0 ATAPERCLSDTPPKACLKPCWGHLPPQPNSLDSGLLCLPCPSSHCPLASLSGSQALLWPG . : ::: : CCDS42 TLAMPMATPPTPPTARPGASPTPAC 300 310 320 >>CCDS46398.1 PAX8 gene_id:7849|Hs108|chr2 (450 aa) initn: 582 init1: 533 opt: 558 Z-score: 438.5 bits: 89.9 E(32554): 4.2e-18 Smith-Waterman score: 558; 50.6% identity (74.7% similar) in 178 aa overlap (1-173:13-190) 10 20 30 40 pF1KE0 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSK .::::: :::::::: .::.:: :: .:.::::::: :.::.::::: CCDS46 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 ILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQD ::::::.:: ..: ::::::..::: :: .:.. : . :..:::::. .: :::.: .: CCDS46 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 KTPSVSSINRVLRA-LQEDQGLPCTRLRSPAVLAPA-VLTPHSG---SETPRGTHPGTGH .::::::::..:. .:. .:: . :.:. .: : :. :.:.. :. . CCDS46 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE0 RNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKL ... .: CCDS46 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF 190 200 210 220 230 240 343 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:31:20 2016 done: Sat Nov 5 04:31:21 2016 Total Scan time: 3.010 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]