Result of FASTA (omim) for
pF1KE0924
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0924, 343 aa
1>>>pF1KE0924 343 - 343 aa - 343 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6423+/-0.00033; mu= 12.9064+/- 0.021
mean_var=181.4565+/-37.283, 0's: 0 Z-trim(121.6): 288 B-trim: 136 in 2/52
Lambda= 0.095211
statistics sampled from 38087 (38479) to 38087 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.782), E-opt: 0.2 (0.451), width: 16
Scan time: 9.630
The best scores are: opt bits E(85289)
NP_006184 (OMIM: 125853,167413,612225,612227) pair ( 343) 2389 339.9 4.9e-93
XP_011514578 (OMIM: 125853,167413,612225,612227) P ( 351) 2389 339.9 4.9e-93
NP_001297088 (OMIM: 106210,120430,136520,148190,16 ( 401) 630 98.3 2.9e-20
NP_001245394 (OMIM: 106210,120430,136520,148190,16 ( 422) 630 98.4 3e-20
NP_001245393 (OMIM: 106210,120430,136520,148190,16 ( 422) 630 98.4 3e-20
NP_001121084 (OMIM: 106210,120430,136520,148190,16 ( 422) 630 98.4 3e-20
NP_000271 (OMIM: 106210,120430,136520,148190,16555 ( 422) 630 98.4 3e-20
NP_001267483 (OMIM: 167414,615545) paired box prot ( 348) 586 92.2 1.8e-18
NP_039246 (OMIM: 167415,218700) paired box protein ( 398) 586 92.3 1.9e-18
XP_016860368 (OMIM: 167415,218700) PREDICTED: pair ( 402) 586 92.3 1.9e-18
NP_001267482 (OMIM: 167414,615545) paired box prot ( 319) 582 91.6 2.4e-18
XP_011510094 (OMIM: 167415,218700) PREDICTED: pair ( 455) 574 90.7 6.5e-18
XP_016860367 (OMIM: 167415,218700) PREDICTED: pair ( 459) 574 90.7 6.6e-18
NP_054698 (OMIM: 167415,218700) paired box protein ( 287) 566 89.4 1e-17
NP_000269 (OMIM: 120330,167409,191830,616002) pair ( 394) 565 89.4 1.4e-17
NP_003979 (OMIM: 120330,167409,191830,616002) pair ( 396) 565 89.4 1.4e-17
NP_003980 (OMIM: 120330,167409,191830,616002) pair ( 409) 565 89.4 1.4e-17
XP_016871777 (OMIM: 120330,167409,191830,616002) P ( 424) 565 89.4 1.5e-17
NP_001291498 (OMIM: 120330,167409,191830,616002) p ( 425) 565 89.4 1.5e-17
XP_016871776 (OMIM: 120330,167409,191830,616002) P ( 427) 565 89.5 1.5e-17
XP_016871775 (OMIM: 120330,167409,191830,616002) P ( 440) 565 89.5 1.5e-17
NP_003978 (OMIM: 120330,167409,191830,616002) pair ( 417) 560 88.8 2.3e-17
NP_003981 (OMIM: 120330,167409,191830,616002) pair ( 432) 560 88.8 2.4e-17
NP_039247 (OMIM: 167415,218700) paired box protein ( 321) 558 88.3 2.4e-17
XP_016871774 (OMIM: 120330,167409,191830,616002) P ( 448) 560 88.8 2.4e-17
XP_016871773 (OMIM: 120330,167409,191830,616002) P ( 463) 560 88.8 2.5e-17
XP_011510096 (OMIM: 167415,218700) PREDICTED: pair ( 387) 558 88.4 2.7e-17
NP_003457 (OMIM: 167415,218700) paired box protein ( 450) 558 88.5 3e-17
NP_001267479 (OMIM: 167414,615545) paired box prot ( 295) 552 87.5 4e-17
NP_001267478 (OMIM: 167414,615545) paired box prot ( 324) 551 87.4 4.7e-17
XP_011510095 (OMIM: 167415,218700) PREDICTED: pair ( 444) 546 86.9 9.2e-17
XP_011510093 (OMIM: 167415,218700) PREDICTED: pair ( 500) 546 86.9 1e-16
XP_011510092 (OMIM: 167415,218700) PREDICTED: pair ( 507) 546 86.9 1e-16
NP_001267481 (OMIM: 167414,615545) paired box prot ( 328) 542 86.2 1.1e-16
NP_001267476 (OMIM: 167414,615545) paired box prot ( 357) 542 86.2 1.2e-16
NP_001267477 (OMIM: 167414,615545) paired box prot ( 362) 542 86.2 1.2e-16
XP_005251538 (OMIM: 167414,615545) PREDICTED: pair ( 390) 542 86.2 1.2e-16
NP_057953 (OMIM: 167414,615545) paired box protein ( 391) 542 86.2 1.2e-16
XP_011516199 (OMIM: 167414,615545) PREDICTED: pair ( 409) 542 86.3 1.3e-16
XP_011516198 (OMIM: 167414,615545) PREDICTED: pair ( 410) 542 86.3 1.3e-16
XP_016871778 (OMIM: 120330,167409,191830,616002) P ( 374) 538 85.7 1.8e-16
XP_016871772 (OMIM: 120330,167409,191830,616002) P ( 483) 538 85.8 2.1e-16
XP_016871771 (OMIM: 120330,167409,191830,616002) P ( 483) 538 85.8 2.1e-16
XP_016871770 (OMIM: 120330,167409,191830,616002) P ( 496) 538 85.8 2.1e-16
NP_006185 (OMIM: 167416,604625) paired box protein ( 341) 483 78.1 3.1e-14
NP_001244025 (OMIM: 167411,615560) paired box prot ( 457) 480 77.8 5e-14
NP_006183 (OMIM: 167411,615560) paired box protein ( 534) 480 77.9 5.6e-14
NP_039236 (OMIM: 167410,268220) paired box protein ( 518) 470 76.5 1.4e-13
NP_001120838 (OMIM: 122880,148820,193500,268220,60 ( 483) 468 76.2 1.6e-13
NP_039230 (OMIM: 122880,148820,193500,268220,60659 ( 206) 453 73.7 4e-13
>>NP_006184 (OMIM: 125853,167413,612225,612227) paired b (343 aa)
initn: 2389 init1: 2389 opt: 2389 Z-score: 1791.3 bits: 339.9 E(85289): 4.9e-93
Smith-Waterman score: 2389; 99.7% identity (99.7% similar) in 343 aa overlap (1-343:1-343)
10 20 30 40 50 60
pF1KE0 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRYYRTGVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRYYRTGVLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSVSSINRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSVSSINRVL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 RALQEDQGLPCTRLRSPAVLAPAVLTPHSGSETPRGTHPGTGHRNRTIFSPSQAEALEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RALQEDQGLPCTRLRSPAVLAPAVLTPHSGSETPRGTHPGTGHRNRTIFSPSQAEALEKE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 FQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGLTVPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGLTVPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 VAPGIISAQQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACLKPCWGHLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VAPGIISAQQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACLKPCWGHLP
250 260 270 280 290 300
310 320 330 340
pF1KE0 PQPNSLDSGLLCLPCPSSHCPLASLSGSQALLWPGCPLLYGLE
:::::::::::::::::::: ::::::::::::::::::::::
NP_006 PQPNSLDSGLLCLPCPSSHCHLASLSGSQALLWPGCPLLYGLE
310 320 330 340
>>XP_011514578 (OMIM: 125853,167413,612225,612227) PREDI (351 aa)
initn: 2389 init1: 2389 opt: 2389 Z-score: 1791.2 bits: 339.9 E(85289): 4.9e-93
Smith-Waterman score: 2389; 99.7% identity (99.7% similar) in 343 aa overlap (1-343:9-351)
10 20 30 40 50
pF1KE0 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGR
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MHQDGISSMNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 YYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 VSSINRVLRALQEDQGLPCTRLRSPAVLAPAVLTPHSGSETPRGTHPGTGHRNRTIFSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSSINRVLRALQEDQGLPCTRLRSPAVLAPAVLTPHSGSETPRGTHPGTGHRNRTIFSPS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 QAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGA
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE0 SQGLTVPRVAPGIISAQQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQGLTVPRVAPGIISAQQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACL
250 260 270 280 290 300
300 310 320 330 340
pF1KE0 KPCWGHLPPQPNSLDSGLLCLPCPSSHCPLASLSGSQALLWPGCPLLYGLE
:::::::::::::::::::::::::::: ::::::::::::::::::::::
XP_011 KPCWGHLPPQPNSLDSGLLCLPCPSSHCHLASLSGSQALLWPGCPLLYGLE
310 320 330 340 350
>>NP_001297088 (OMIM: 106210,120430,136520,148190,165550 (401 aa)
initn: 873 init1: 618 opt: 630 Z-score: 484.8 bits: 98.3 E(85289): 2.9e-20
Smith-Waterman score: 812; 42.5% identity (60.6% similar) in 381 aa overlap (1-336:8-372)
10 20 30 40 50
pF1KE0 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRY
.:::::.:::::::: .:::.::.:: :: :::::::::.:::::::::::::
NP_001 MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 YRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSV
:.:: ..:..:::::::.::: ::..::: : :::..:::::. .: .::.::.:. :::
NP_001 YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV
70 80 90 100 110 120
120 130 140 150 160
pF1KE0 SSINRVLRAL-QEDQGLPCTRLRSPAVLAPAVLTPHSGSETPR-GTHPGTG---------
:::::::: : .: : . . . . :. ..:: : : .:::.
NP_001 SSINRVLRNLASEKQQMGADGMYDKLRM----LNGQTGSWGTRPGWYPGTSVPGQPTQDG
130 140 150 160 170
170 180
pF1KE0 ----------------------------------HRNRTIFSPSQAEALEKEFQRGQYPD
.:::: :. : :::::::.: .:::
NP_001 CQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPD
180 190 200 210 220 230
190 200 210 220 230 240
pF1KE0 SVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGLTVPRVAPGIISA
:: .::. .::: ..::::::::::::.:::. . . . . . .: .. .. ..
NP_001 VFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPS-HIP-ISSSFSTS
240 250 260 270 280 290
250 260 270 280 290 300
pF1KE0 QQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACLKPCWGHLPPQPNSLDS
.: ::. . .. : . :: : :: . ..:: : .. .
NP_001 VYQPIPQPTTPVSSFTS-GSMLGRT--DTALTNTYSALPPMPSFTMA-NNLPMQVSAAGG
300 310 320 330 340 350
310 320 330 340
pF1KE0 GLLCLPCPSSHCPLASLSGSQALLWPGCPLLYGLE
:: : : . : :: :. ::
NP_001 GLHN-PGPR---EVRSGSGPADLI--GCVCTLESFSHYSDWLDQSSRRQSIPSLLSD
360 370 380 390 400
>>NP_001245394 (OMIM: 106210,120430,136520,148190,165550 (422 aa)
initn: 935 init1: 618 opt: 630 Z-score: 484.5 bits: 98.4 E(85289): 3e-20
Smith-Waterman score: 821; 42.1% identity (60.7% similar) in 387 aa overlap (1-341:8-366)
10 20 30 40 50
pF1KE0 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRY
.:::::.:::::::: .:::.::.:: :: :::::::::.:::::::::::::
NP_001 MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 YRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSV
:.:: ..:..:::::::.::: ::..::: : :::..:::::. .: .::.::.:. :::
NP_001 YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV
70 80 90 100 110 120
120 130 140 150 160
pF1KE0 SSINRVLRAL-QEDQGLPCTRLRSPAVLAPAVLTPHSGSETPR-GTHPGTG---------
:::::::: : .: : . . . . :. ..:: : : .:::.
NP_001 SSINRVLRNLASEKQQMGADGMYDKLRM----LNGQTGSWGTRPGWYPGTSVPGQPTQDG
130 140 150 160 170
170 180
pF1KE0 ----------------------------------HRNRTIFSPSQAEALEKEFQRGQYPD
.:::: :. : :::::::.: .:::
NP_001 CQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPD
180 190 200 210 220 230
190 200 210 220 230 240
pF1KE0 SVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGLTVPRVAPGIISA
:: .::. .::: ..::::::::::::.:::. . . :. ..: : ::.
NP_001 VFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRR-----QASNTPSHIP--ISS
240 250 260 270 280
250 260 270 280 290 300
pF1KE0 QQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACLKPCWGHLPPQPN-SLD
. : .. : .: : .... .:: : .. :::.:. ..
NP_001 SFS----TSVYQPIPQPTTPVS---SFTSGSMLGRTDTA----LTNTYSALPPMPSFTMA
290 300 310 320 330
310 320 330 340
pF1KE0 SGLLCLPCPSSHCPLASLSGSQALLWPGCPLLYGLE
..: : :. : ..: . . : : . :
NP_001 NNLPMQP------PVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTT
340 350 360 370 380 390
NP_001 STGLISPGVSVPVQVPGSEPDMSQYWPRLQ
400 410 420
>>NP_001245393 (OMIM: 106210,120430,136520,148190,165550 (422 aa)
initn: 935 init1: 618 opt: 630 Z-score: 484.5 bits: 98.4 E(85289): 3e-20
Smith-Waterman score: 821; 42.1% identity (60.7% similar) in 387 aa overlap (1-341:8-366)
10 20 30 40 50
pF1KE0 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRY
.:::::.:::::::: .:::.::.:: :: :::::::::.:::::::::::::
NP_001 MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 YRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSV
:.:: ..:..:::::::.::: ::..::: : :::..:::::. .: .::.::.:. :::
NP_001 YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV
70 80 90 100 110 120
120 130 140 150 160
pF1KE0 SSINRVLRAL-QEDQGLPCTRLRSPAVLAPAVLTPHSGSETPR-GTHPGTG---------
:::::::: : .: : . . . . :. ..:: : : .:::.
NP_001 SSINRVLRNLASEKQQMGADGMYDKLRM----LNGQTGSWGTRPGWYPGTSVPGQPTQDG
130 140 150 160 170
170 180
pF1KE0 ----------------------------------HRNRTIFSPSQAEALEKEFQRGQYPD
.:::: :. : :::::::.: .:::
NP_001 CQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPD
180 190 200 210 220 230
190 200 210 220 230 240
pF1KE0 SVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGLTVPRVAPGIISA
:: .::. .::: ..::::::::::::.:::. . . :. ..: : ::.
NP_001 VFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRR-----QASNTPSHIP--ISS
240 250 260 270 280
250 260 270 280 290 300
pF1KE0 QQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACLKPCWGHLPPQPN-SLD
. : .. : .: : .... .:: : .. :::.:. ..
NP_001 SFS----TSVYQPIPQPTTPVS---SFTSGSMLGRTDTA----LTNTYSALPPMPSFTMA
290 300 310 320 330
310 320 330 340
pF1KE0 SGLLCLPCPSSHCPLASLSGSQALLWPGCPLLYGLE
..: : :. : ..: . . : : . :
NP_001 NNLPMQP------PVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTT
340 350 360 370 380 390
NP_001 STGLISPGVSVPVQVPGSEPDMSQYWPRLQ
400 410 420
>>NP_001121084 (OMIM: 106210,120430,136520,148190,165550 (422 aa)
initn: 935 init1: 618 opt: 630 Z-score: 484.5 bits: 98.4 E(85289): 3e-20
Smith-Waterman score: 821; 42.1% identity (60.7% similar) in 387 aa overlap (1-341:8-366)
10 20 30 40 50
pF1KE0 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRY
.:::::.:::::::: .:::.::.:: :: :::::::::.:::::::::::::
NP_001 MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 YRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSV
:.:: ..:..:::::::.::: ::..::: : :::..:::::. .: .::.::.:. :::
NP_001 YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV
70 80 90 100 110 120
120 130 140 150 160
pF1KE0 SSINRVLRAL-QEDQGLPCTRLRSPAVLAPAVLTPHSGSETPR-GTHPGTG---------
:::::::: : .: : . . . . :. ..:: : : .:::.
NP_001 SSINRVLRNLASEKQQMGADGMYDKLRM----LNGQTGSWGTRPGWYPGTSVPGQPTQDG
130 140 150 160 170
170 180
pF1KE0 ----------------------------------HRNRTIFSPSQAEALEKEFQRGQYPD
.:::: :. : :::::::.: .:::
NP_001 CQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPD
180 190 200 210 220 230
190 200 210 220 230 240
pF1KE0 SVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGLTVPRVAPGIISA
:: .::. .::: ..::::::::::::.:::. . . :. ..: : ::.
NP_001 VFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRR-----QASNTPSHIP--ISS
240 250 260 270 280
250 260 270 280 290 300
pF1KE0 QQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACLKPCWGHLPPQPN-SLD
. : .. : .: : .... .:: : .. :::.:. ..
NP_001 SFS----TSVYQPIPQPTTPVS---SFTSGSMLGRTDTA----LTNTYSALPPMPSFTMA
290 300 310 320 330
310 320 330 340
pF1KE0 SGLLCLPCPSSHCPLASLSGSQALLWPGCPLLYGLE
..: : :. : ..: . . : : . :
NP_001 NNLPMQP------PVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTT
340 350 360 370 380 390
NP_001 STGLISPGVSVPVQVPGSEPDMSQYWPRLQ
400 410 420
>>NP_000271 (OMIM: 106210,120430,136520,148190,165550,19 (422 aa)
initn: 935 init1: 618 opt: 630 Z-score: 484.5 bits: 98.4 E(85289): 3e-20
Smith-Waterman score: 821; 42.1% identity (60.7% similar) in 387 aa overlap (1-341:8-366)
10 20 30 40 50
pF1KE0 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRY
.:::::.:::::::: .:::.::.:: :: :::::::::.:::::::::::::
NP_000 MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 YRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSV
:.:: ..:..:::::::.::: ::..::: : :::..:::::. .: .::.::.:. :::
NP_000 YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV
70 80 90 100 110 120
120 130 140 150 160
pF1KE0 SSINRVLRAL-QEDQGLPCTRLRSPAVLAPAVLTPHSGSETPR-GTHPGTG---------
:::::::: : .: : . . . . :. ..:: : : .:::.
NP_000 SSINRVLRNLASEKQQMGADGMYDKLRM----LNGQTGSWGTRPGWYPGTSVPGQPTQDG
130 140 150 160 170
170 180
pF1KE0 ----------------------------------HRNRTIFSPSQAEALEKEFQRGQYPD
.:::: :. : :::::::.: .:::
NP_000 CQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPD
180 190 200 210 220 230
190 200 210 220 230 240
pF1KE0 SVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGLTVPRVAPGIISA
:: .::. .::: ..::::::::::::.:::. . . :. ..: : ::.
NP_000 VFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRR-----QASNTPSHIP--ISS
240 250 260 270 280
250 260 270 280 290 300
pF1KE0 QQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACLKPCWGHLPPQPN-SLD
. : .. : .: : .... .:: : .. :::.:. ..
NP_000 SFS----TSVYQPIPQPTTPVS---SFTSGSMLGRTDTA----LTNTYSALPPMPSFTMA
290 300 310 320 330
310 320 330 340
pF1KE0 SGLLCLPCPSSHCPLASLSGSQALLWPGCPLLYGLE
..: : :. : ..: . . : : . :
NP_000 NNLPMQP------PVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTT
340 350 360 370 380 390
NP_000 STGLISPGVSVPVQVPGSEPDMSQYWPRLQ
400 410 420
>>NP_001267483 (OMIM: 167414,615545) paired box protein (348 aa)
initn: 578 init1: 531 opt: 586 Z-score: 452.8 bits: 92.2 E(85289): 1.8e-18
Smith-Waterman score: 586; 38.2% identity (61.8% similar) in 322 aa overlap (1-308:20-325)
10 20 30 40
pF1KE0 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKV
.:::::.:::::::: .::.::.:: .:.::::::: :.:
NP_001 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 SNGCVSKILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCA
:.:::::::::::.:: ..: ::::::..::: :: .::. : . :..:::::. .: :
NP_001 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLA
70 80 90 100 110 120
110 120 130 140 150
pF1KE0 EGLCTQDKTPSVSSINRVLRA-LQE--DQGLPCTRLRSPAVLAPAVLTPHS--GSETPRG
: .: .: .::::::::..:. .:. .: .: . .: .. : . :: : . :
NP_001 ERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASS-HSIGIQESPVPNGHSLPGRDFLRK
130 140 150 160 170
160 170 180 190 200 210
pF1KE0 THPGTGHRNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAK
: .:. .: :.:.. :.: .: : . .: ::.:.. .: .
NP_001 QMRGD------LFTQQQLEVLDRVFERQHYSDIFT----TTEPIKPEQTTE--YSAMASL
180 190 200 210 220
220 230 240 250 260 270
pF1KE0 WRRQEKLKWEMQLPG-ASQGLTVP--RVAPGIISAQQSPGSVPTAALPALEPLGPSCYQL
. .: .. : :. : .:: . : . . . . ..: : . : : . :.
NP_001 AGGLDDMKANLASPTPADIGSSVPGPQSYPIVTGRDLASTTLPGYP-PHVPPAGQGSYSA
230 240 250 260 270 280
280 290 300 310 320
pF1KE0 CWATA--PERCLSDTP---PK-ACLKPCWGHLPPQPNSLDSGLLCLPCPSSHCPLASLSG
:. : .: .: :. . . : :.:. : :
NP_001 PTLTGMVPGSEFSGSPYSHPQYSSYNDSWRF--PNPGLLGSPYYYSAAARGAAPPAAATA
290 300 310 320 330 340
330 340
pF1KE0 SQALLWPGCPLLYGLE
NP_001 YDRH
>>NP_039246 (OMIM: 167415,218700) paired box protein Pax (398 aa)
initn: 619 init1: 533 opt: 586 Z-score: 452.1 bits: 92.3 E(85289): 1.9e-18
Smith-Waterman score: 587; 36.8% identity (55.6% similar) in 383 aa overlap (1-321:13-385)
10 20 30 40
pF1KE0 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSK
.::::: :::::::: .::.:: :: .:.::::::: :.::.:::::
NP_039 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 ILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQD
::::::.:: ..: ::::::..::: :: .:.. : . :..:::::. .: :::.: .:
NP_039 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND
70 80 90 100 110 120
110 120 130 140 150
pF1KE0 KTPSVSSINRVLRA-LQEDQGLP---C--TRLRSPA-VLAP--AVLTPHSGSETPRGT--
.::::::::..:. .:. .:: : :. ::. .: : :: :.: . :.
NP_039 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY
130 140 150 160 170 180
160 170 180
pF1KE0 ---------HPGTGHRN--------------------------RT-IFSPSQAEALEKEF
.::. .:. :: :: . : :: :
NP_039 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF
190 200 210 220 230 240
190 200 210 220 230
pF1KE0 QRGQYPDSVARGKLATATS--LPEDTVRVWFSNRRAKWR-RQEKLKWEMQLPGASQGLTV
.: .::.. : . . . . : . ... .: . : .. : :
NP_039 ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNL-----STHQTY
250 260 270 280 290
240 250 260 270 280 290
pF1KE0 PRVA--PGIISAQQSPGSVPTAALPALEP-LG-----PSCYQLCWATAPERCLSDTPPKA
: :: : : ....::: :. .: : : : :: : .: :: :: : .
NP_039 PVVAAPPFWICSKSAPGSRPSMPFPMLPPCTGSSRARPSSQGERWW-GP-RC-PDTHPTS
300 310 320 330 340 350
300 310 320 330 340
pF1KE0 CLKPC-WGHLPPQPNSL---DSGLLCLPCPSSHCPLASLSGSQALLWPGCPLLYGLE
: . .:: :.. . . : .: . :
NP_039 --PPADRAAMPPLPSQAWWQEVNTLAMPMATPPTPPTARPGASPTPAC
360 370 380 390
>>XP_016860368 (OMIM: 167415,218700) PREDICTED: paired b (402 aa)
initn: 619 init1: 533 opt: 586 Z-score: 452.1 bits: 92.3 E(85289): 1.9e-18
Smith-Waterman score: 586; 36.6% identity (60.0% similar) in 350 aa overlap (1-337:13-346)
10 20 30 40
pF1KE0 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSK
.::::: :::::::: .::.:: :: .:.::::::: :.::.:::::
XP_016 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 ILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQD
::::::.:: ..: ::::::..::: :: .:.. : . :..:::::. .: :::.: .:
XP_016 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 KTPSVSSINRVLRA-LQEDQGLPCTRLRSPAVLAPA-VLTPHSG---SETPRGTHPGTGH
.::::::::..:. .:. .:: . :.:. .: : :. :.:.. :. .
XP_016 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE0 RNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRV-WFSNRRAKWRRQEK
... .: . ..... .. . ...: :. .:. :: :..
XP_016 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFS--------QHH
190 200 210 220 230
230 240 250 260 270 280
pF1KE0 LKWEMQLPGASQGLTVPRVAPGIISAQQSPGSVPTAALPALEP-LGPSCYQLCWATAPE-
:. .. : : ..:. ...: : : :: :. : . : ...:
XP_016 LE-PLECPFERQHYPEAYASPSHTKGEQ--GLYP---LPLLNSTLDDGKATLTPSNTPLG
240 250 260 270 280
290 300 310 320 330
pF1KE0 RCLS--DTPPKACLKPCWGHLPPQPNSLDSGLLCL--PCPSSHCPLASLSGSQALLW-PG
: :: .: : . : : :.: : . . :: .: : .: . : :
XP_016 RNLSTHQTYPVVAAPPFWICSKSAPGSRPSMPFPMLPPCTGSSRARPSSQGER--WWGPR
290 300 310 320 330 340
340
pF1KE0 CPLLYGLE
::
XP_016 CPDTHPTSPPADRAAMPPLPSQAWWQVRRGPAGRGALQRGSIGARWDTRSKRHTVPYS
350 360 370 380 390 400
343 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 04:31:21 2016 done: Sat Nov 5 04:31:23 2016
Total Scan time: 9.630 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]