FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0925, 328 aa 1>>>pF1KE0925 328 - 328 aa - 328 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5235+/-0.00101; mu= 10.3228+/- 0.061 mean_var=87.8902+/-16.879, 0's: 0 Z-trim(105.4): 24 B-trim: 0 in 0/51 Lambda= 0.136806 statistics sampled from 8400 (8412) to 8400 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.624), E-opt: 0.2 (0.258), width: 16 Scan time: 1.940 The best scores are: opt bits E(32554) CCDS55668.1 UCHL5 gene_id:51377|Hs108|chr1 ( 328) 2159 436.1 1.8e-122 CCDS1378.1 UCHL5 gene_id:51377|Hs108|chr1 ( 329) 2147 433.8 9.4e-122 CCDS55669.1 UCHL5 gene_id:51377|Hs108|chr1 ( 316) 2082 420.9 6.6e-118 CCDS55670.1 UCHL5 gene_id:51377|Hs108|chr1 ( 326) 2076 419.7 1.5e-117 CCDS2853.1 BAP1 gene_id:8314|Hs108|chr3 ( 729) 583 125.2 1.6e-28 CCDS9453.1 UCHL3 gene_id:7347|Hs108|chr13 ( 230) 299 69.0 4.3e-12 >>CCDS55668.1 UCHL5 gene_id:51377|Hs108|chr1 (328 aa) initn: 2159 init1: 2159 opt: 2159 Z-score: 2312.2 bits: 436.1 E(32554): 1.8e-122 Smith-Waterman score: 2159; 100.0% identity (100.0% similar) in 328 aa overlap (1-328:1-328) 10 20 30 40 50 60 pF1KE0 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 GEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 FDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 FDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 QLAEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 QLAEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLK 250 260 270 280 290 300 310 320 pF1KE0 TLAEHQQLIPLVEKAKEKQNAKKAQETK :::::::::::::::::::::::::::: CCDS55 TLAEHQQLIPLVEKAKEKQNAKKAQETK 310 320 >>CCDS1378.1 UCHL5 gene_id:51377|Hs108|chr1 (329 aa) initn: 1669 init1: 1639 opt: 2147 Z-score: 2299.3 bits: 433.8 E(32554): 9.4e-122 Smith-Waterman score: 2147; 99.7% identity (99.7% similar) in 329 aa overlap (1-328:1-329) 10 20 30 40 50 60 pF1KE0 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 GEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 GEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 FDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 FDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQR 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 QLAEE-PMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELL ::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 QLAEEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELL 250 260 270 280 290 300 300 310 320 pF1KE0 KTLAEHQQLIPLVEKAKEKQNAKKAQETK ::::::::::::::::::::::::::::: CCDS13 KTLAEHQQLIPLVEKAKEKQNAKKAQETK 310 320 >>CCDS55669.1 UCHL5 gene_id:51377|Hs108|chr1 (316 aa) initn: 2108 init1: 2082 opt: 2082 Z-score: 2230.3 bits: 420.9 E(32554): 6.6e-118 Smith-Waterman score: 2082; 99.7% identity (100.0% similar) in 316 aa overlap (1-316:1-316) 10 20 30 40 50 60 pF1KE0 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 GEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 FDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 FDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 QLAEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 QLAEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLK 250 260 270 280 290 300 310 320 pF1KE0 TLAEHQQLIPLVEKAKEKQNAKKAQETK ::::::::::::::.: CCDS55 TLAEHQQLIPLVEKGK 310 >>CCDS55670.1 UCHL5 gene_id:51377|Hs108|chr1 (326 aa) initn: 2076 init1: 2076 opt: 2076 Z-score: 2223.7 bits: 419.7 E(32554): 1.5e-117 Smith-Waterman score: 2076; 100.0% identity (100.0% similar) in 314 aa overlap (1-314:1-314) 10 20 30 40 50 60 pF1KE0 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 GEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 FDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 FDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 QLAEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 QLAEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLK 250 260 270 280 290 300 310 320 pF1KE0 TLAEHQQLIPLVEKAKEKQNAKKAQETK :::::::::::::: CCDS55 TLAEHQQLIPLVEKFEKHFEKTLLGK 310 320 >>CCDS2853.1 BAP1 gene_id:8314|Hs108|chr3 (729 aa) initn: 725 init1: 149 opt: 583 Z-score: 625.5 bits: 125.2 E(32554): 1.6e-28 Smith-Waterman score: 644; 40.8% identity (68.2% similar) in 289 aa overlap (4-272:2-284) 10 20 30 40 50 60 pF1KE0 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP : : : .:::::.:: :.. :: .:.:::::..:. . ::.:.:::::: CCDS28 MNKG-WLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKC---QGPVYGFIFLFKWIE 10 20 30 40 50 70 80 90 100 110 pF1KE0 GEEPA---------GSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETL .. ::..:. ....:::.:.: :.:::.:..::::::. .: :: :: CCDS28 ERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCS--SVDLGPTL 60 70 80 90 100 110 120 130 140 150 160 pF1KE0 SEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTK----TSAKEEDAFHFVS :..:.:...:. :: :..:. . ..::: :: . .. : .... .:::::: CCDS28 SRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVS 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 YVPVNGRLYELDGLREGPIDLGACNQDD-WISAVRPVIEKRIQKYSEGE----IRFNLMA :::..:::.:::::. ::: : ..:. : . .: :: .:: . :: ::::::: CCDS28 YVPITGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMA 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 IVSDRKMIYEQKIAELQ--RQLAEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRY .: ::.. :: .. :. :: . : .. .. ::.. .....: :: CCDS28 VVPDRRIKYEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSASNKS 240 250 260 270 280 290 290 300 310 320 pF1KE0 KIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAKEKQNAKKAQETK CCDS28 PLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTP 300 310 320 330 340 350 >>CCDS9453.1 UCHL3 gene_id:7347|Hs108|chr13 (230 aa) initn: 177 init1: 98 opt: 299 Z-score: 330.6 bits: 69.0 E(32554): 4.3e-12 Smith-Waterman score: 299; 29.4% identity (62.3% similar) in 228 aa overlap (8-223:6-227) 10 20 30 40 50 pF1KE0 MTGNAGEWCLMESDPGVFTELIKGFGCRGA-QVEEIWSLEPENFEKL-KPVHGLIFLF-- : .:..: : ....: .: . : ......:: . . .:: ....:: CCDS94 MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPI 10 20 30 40 50 60 70 80 90 100 pF1KE0 --KWQ----PGEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHL--G :.. :: : :: ....: ::.:.:::.: ... .. : ... .:. : CCDS94 TEKYEVFRTEEEEKIKSQGQDVT-SSVYFMKQTISNACGTIGLIHAIAN-NKDKMHFESG 60 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 ETLSEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSY ::..: : : :.. .. : : :.:: .:.. :.. . : : :. .::.. CCDS94 STLKKFLEESVSMSPEERARYLENYDAIRVTHETSAHEGQTE---APSIDEKVDLHFIAL 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 VPVNGRLYELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRK : :.:.:::::: . ::. : ... . . : .: ... . :.::: .:. CCDS94 VHVDGHLYELDGRKPFPINHGETSDETLLEDAIEVCKKFMER-DPDELRFNAIALSAA 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 MIYEQKIAELQRQLAEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRK 328 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:31:59 2016 done: Sat Nov 5 04:31:59 2016 Total Scan time: 1.940 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]