FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0930, 385 aa 1>>>pF1KE0930 385 - 385 aa - 385 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2282+/-0.000789; mu= 13.0596+/- 0.048 mean_var=93.2304+/-18.616, 0's: 0 Z-trim(109.4): 17 B-trim: 0 in 0/49 Lambda= 0.132830 statistics sampled from 10846 (10862) to 10846 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.334), width: 16 Scan time: 2.800 The best scores are: opt bits E(32554) CCDS54650.1 TFDP2 gene_id:7029|Hs108|chr3 ( 446) 2502 489.5 2.5e-138 CCDS54648.1 TFDP2 gene_id:7029|Hs108|chr3 ( 418) 2495 488.1 6e-138 CCDS43159.1 TFDP2 gene_id:7029|Hs108|chr3 ( 386) 2490 487.2 1.1e-137 CCDS54649.1 TFDP2 gene_id:7029|Hs108|chr3 ( 349) 2226 436.5 1.7e-122 CCDS54647.1 TFDP2 gene_id:7029|Hs108|chr3 ( 310) 2006 394.3 7.6e-110 CCDS9538.1 TFDP1 gene_id:7027|Hs108|chr13 ( 410) 1334 265.6 5.6e-71 CCDS14636.2 TFDP3 gene_id:51270|Hs108|chrX ( 405) 1011 203.7 2.4e-52 >>CCDS54650.1 TFDP2 gene_id:7029|Hs108|chr3 (446 aa) initn: 2502 init1: 2502 opt: 2502 Z-score: 2596.9 bits: 489.5 E(32554): 2.5e-138 Smith-Waterman score: 2502; 100.0% identity (100.0% similar) in 385 aa overlap (1-385:62-446) 10 20 30 pF1KE0 MIISTPQRLTSSGSVLIGSPYTPAPAMVTQ :::::::::::::::::::::::::::::: CCDS54 FVAFPVSNTNSPTKILPKTLGPINVNVGPQMIISTPQRLTSSGSVLIGSPYTPAPAMVTQ 40 50 60 70 80 90 40 50 60 70 80 90 pF1KE0 THIAEATGWVPGDRKRARKFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 THIAEATGWVPGDRKRARKFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSY 100 110 120 130 140 150 100 110 120 130 140 150 pF1KE0 NEVADELVSEFTNSNNHLAADSAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 NEVADELVSEFTNSNNHLAADSAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPT 160 170 180 190 200 210 160 170 180 190 200 210 pF1KE0 NSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPALNST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 NSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPALNST 220 230 240 250 260 270 220 230 240 250 260 270 pF1KE0 IQLPFIIINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 IQLPFIIINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSL 280 290 300 310 320 330 280 290 300 310 320 330 pF1KE0 EDLKLAKSLVPKALEGYITDISTGPSWLNQGLLLNSTQSVSNLDLTTGATLPQSSVNQGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 EDLKLAKSLVPKALEGYITDISTGPSWLNQGLLLNSTQSVSNLDLTTGATLPQSSVNQGL 340 350 360 370 380 390 340 350 360 370 380 pF1KE0 CLDAEVALATGQFLAPNSHQSSSAASHCSESRGETPCSFNDEDEEDDEEDSSSPE ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 CLDAEVALATGQFLAPNSHQSSSAASHCSESRGETPCSFNDEDEEDDEEDSSSPE 400 410 420 430 440 >>CCDS54648.1 TFDP2 gene_id:7029|Hs108|chr3 (418 aa) initn: 2495 init1: 2495 opt: 2495 Z-score: 2590.1 bits: 488.1 E(32554): 6e-138 Smith-Waterman score: 2495; 100.0% identity (100.0% similar) in 384 aa overlap (2-385:35-418) 10 20 30 pF1KE0 MIISTPQRLTSSGSVLIGSPYTPAPAMVTQT :::::::::::::::::::::::::::::: CCDS54 GIIFEAENKPSPGTESAGTFILDLSATSRTIISTPQRLTSSGSVLIGSPYTPAPAMVTQT 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 HIAEATGWVPGDRKRARKFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 HIAEATGWVPGDRKRARKFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSYN 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 EVADELVSEFTNSNNHLAADSAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 EVADELVSEFTNSNNHLAADSAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTN 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE0 SAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPALNSTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 SAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPALNSTI 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE0 QLPFIIINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 QLPFIIINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLE 250 260 270 280 290 300 280 290 300 310 320 330 pF1KE0 DLKLAKSLVPKALEGYITDISTGPSWLNQGLLLNSTQSVSNLDLTTGATLPQSSVNQGLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 DLKLAKSLVPKALEGYITDISTGPSWLNQGLLLNSTQSVSNLDLTTGATLPQSSVNQGLC 310 320 330 340 350 360 340 350 360 370 380 pF1KE0 LDAEVALATGQFLAPNSHQSSSAASHCSESRGETPCSFNDEDEEDDEEDSSSPE :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LDAEVALATGQFLAPNSHQSSSAASHCSESRGETPCSFNDEDEEDDEEDSSSPE 370 380 390 400 410 >>CCDS43159.1 TFDP2 gene_id:7029|Hs108|chr3 (386 aa) initn: 1775 init1: 1775 opt: 2490 Z-score: 2585.4 bits: 487.2 E(32554): 1.1e-137 Smith-Waterman score: 2490; 99.7% identity (99.7% similar) in 386 aa overlap (1-385:1-386) 10 20 30 40 50 60 pF1KE0 MIISTPQRLTSSGSVLIGSPYTPAPAMVTQTHIAEATGWVPGDRKRARKFIDSDFSESKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MIISTPQRLTSSGSVLIGSPYTPAPAMVTQTHIAEATGWVPGDRKRARKFIDSDFSESKR 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 SKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFTNSNNHLAADS-AYDQKNI :::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::: CCDS43 SKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFTNSNNHLAADSQAYDQKNI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 RRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 RRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQE 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 LLLQQIAFKNLVQRNRQNEQQNQGPPALNSTIQLPFIIINTSRKTVIDCSISSDKFEYLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LLLQQIAFKNLVQRNRQNEQQNQGPPALNSTIQLPFIIINTSRKTVIDCSISSDKFEYLF 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE0 NFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKLAKSLVPKALEGYITDISTGPSWLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 NFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKLAKSLVPKALEGYITDISTGPSWLN 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE0 QGLLLNSTQSVSNLDLTTGATLPQSSVNQGLCLDAEVALATGQFLAPNSHQSSSAASHCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 QGLLLNSTQSVSNLDLTTGATLPQSSVNQGLCLDAEVALATGQFLAPNSHQSSSAASHCS 310 320 330 340 350 360 360 370 380 pF1KE0 ESRGETPCSFNDEDEEDDEEDSSSPE :::::::::::::::::::::::::: CCDS43 ESRGETPCSFNDEDEEDDEEDSSSPE 370 380 >>CCDS54649.1 TFDP2 gene_id:7029|Hs108|chr3 (349 aa) initn: 2226 init1: 2226 opt: 2226 Z-score: 2312.7 bits: 436.5 E(32554): 1.7e-122 Smith-Waterman score: 2226; 100.0% identity (100.0% similar) in 343 aa overlap (43-385:7-349) 20 30 40 50 60 70 pF1KE0 GSVLIGSPYTPAPAMVTQTHIAEATGWVPGDRKRARKFIDSDFSESKRSKKGDKNGKGLR :::::::::::::::::::::::::::::: CCDS54 MLDPKCDRKRARKFIDSDFSESKRSKKGDKNGKGLR 10 20 30 80 90 100 110 120 130 pF1KE0 HFSMKVCEKVQRKGTTSYNEVADELVSEFTNSNNHLAADSAYDQKNIRRRVYDALNVLMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 HFSMKVCEKVQRKGTTSYNEVADELVSEFTNSNNHLAADSAYDQKNIRRRVYDALNVLMA 40 50 60 70 80 90 140 150 160 170 180 190 pF1KE0 MNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQ 100 110 120 130 140 150 200 210 220 230 240 250 pF1KE0 RNRQNEQQNQGPPALNSTIQLPFIIINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 RNRQNEQQNQGPPALNSTIQLPFIIINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIE 160 170 180 190 200 210 260 270 280 290 300 310 pF1KE0 VLKRMGMSFGLESGKCSLEDLKLAKSLVPKALEGYITDISTGPSWLNQGLLLNSTQSVSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 VLKRMGMSFGLESGKCSLEDLKLAKSLVPKALEGYITDISTGPSWLNQGLLLNSTQSVSN 220 230 240 250 260 270 320 330 340 350 360 370 pF1KE0 LDLTTGATLPQSSVNQGLCLDAEVALATGQFLAPNSHQSSSAASHCSESRGETPCSFNDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LDLTTGATLPQSSVNQGLCLDAEVALATGQFLAPNSHQSSSAASHCSESRGETPCSFNDE 280 290 300 310 320 330 380 pF1KE0 DEEDDEEDSSSPE ::::::::::::: CCDS54 DEEDDEEDSSSPE 340 >>CCDS54647.1 TFDP2 gene_id:7029|Hs108|chr3 (310 aa) initn: 2006 init1: 2006 opt: 2006 Z-score: 2085.6 bits: 394.3 E(32554): 7.6e-110 Smith-Waterman score: 2006; 100.0% identity (100.0% similar) in 310 aa overlap (76-385:1-310) 50 60 70 80 90 100 pF1KE0 RARKFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFTNSN :::::::::::::::::::::::::::::: CCDS54 MKVCEKVQRKGTTSYNEVADELVSEFTNSN 10 20 30 110 120 130 140 150 160 pF1KE0 NHLAADSAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 NHLAADSAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQR 40 50 60 70 80 90 170 180 190 200 210 220 pF1KE0 RIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPALNSTIQLPFIIINTSRKTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 RIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPALNSTIQLPFIIINTSRKTV 100 110 120 130 140 150 230 240 250 260 270 280 pF1KE0 IDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKLAKSLVPKALE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 IDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKLAKSLVPKALE 160 170 180 190 200 210 290 300 310 320 330 340 pF1KE0 GYITDISTGPSWLNQGLLLNSTQSVSNLDLTTGATLPQSSVNQGLCLDAEVALATGQFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 GYITDISTGPSWLNQGLLLNSTQSVSNLDLTTGATLPQSSVNQGLCLDAEVALATGQFLA 220 230 240 250 260 270 350 360 370 380 pF1KE0 PNSHQSSSAASHCSESRGETPCSFNDEDEEDDEEDSSSPE :::::::::::::::::::::::::::::::::::::::: CCDS54 PNSHQSSSAASHCSESRGETPCSFNDEDEEDDEEDSSSPE 280 290 300 310 >>CCDS9538.1 TFDP1 gene_id:7027|Hs108|chr13 (410 aa) initn: 1242 init1: 1028 opt: 1334 Z-score: 1387.8 bits: 265.6 E(32554): 5.6e-71 Smith-Waterman score: 1432; 60.9% identity (79.8% similar) in 386 aa overlap (1-385:62-408) 10 20 30 pF1KE0 MIISTPQRLTSSGSVLIGSPYTPAPAMVTQ ..:.:::: ..:.....:::.::. ...: CCDS95 VAVHPSTVNPLGKQLLPKTFGQSNVNIAQQVVIGTPQRPAASNTLVVGSPHTPSTHFASQ 40 50 60 70 80 90 40 50 60 70 80 90 pF1KE0 THIAEATGWVPGDRKRARKFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSY .. .... : : ::..::.::::::::::::::::::::::::: CCDS95 NQPSDSSPWSAG----------------KRNRKGEKNGKGLRHFSMKVCEKVQRKGTTSY 100 110 120 130 100 110 120 130 140 pF1KE0 NEVADELVSEFTNSNNH-LAADSAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLP ::::::::.::. ..:: : .:::::::::::::::::::::::::::::::::::::: CCDS95 NEVADELVAEFSAADNHILPNESAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLP 140 150 160 170 180 190 150 160 170 180 190 200 pF1KE0 TNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPALNS :::::::::::.:.:::.::::::..:::::.::::::::::::::. ::: . :: :: CCDS95 TNSAQECQNLEVERQRRLERIKQKQSQLQELILQQIAFKNLVQRNRHAEQQASRPPPPNS 200 210 220 230 240 250 210 220 230 240 250 260 pF1KE0 TIQLPFIIINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCS .:.:::::.:::.:::::::::.:::::::::::::::::::::::::::. :::::.:: CCDS95 VIHLPFIIVNTSKKTVIDCSISNDKFEYLFNFDNTFEIHDDIEVLKRMGMACGLESGSCS 260 270 280 290 300 310 270 280 290 300 310 320 pF1KE0 LEDLKLAKSLVPKALEGYITDISTGPSWLNQGLLLNSTQSVSNLDLTTGATLPQSSVNQG ::::.:.:::::::: :.:... : :...... :.:: :. . :....: CCDS95 AEDLKMARSLVPKALEPYVTEMAQGTV---GGVFITTAGSTSN-----GTRFSASDLTNG 320 330 340 350 360 330 340 350 360 370 380 pF1KE0 LCLDAEVALATGQFLAPNSHQSSSAASHCSESRGETPCSFNDEDEEDDEEDSSSPE :. ::: :: .:. : :: ::: :. ::.:.:.. . . : CCDS95 ----ADGMLAT-----------SSNGSQYSGSRVETPVSYVGEDDEEDDDFNENDEDD 370 380 390 400 410 >>CCDS14636.2 TFDP3 gene_id:51270|Hs108|chrX (405 aa) initn: 1071 init1: 856 opt: 1011 Z-score: 1053.4 bits: 203.7 E(32554): 2.4e-52 Smith-Waterman score: 1074; 50.1% identity (74.8% similar) in 385 aa overlap (1-383:57-399) 10 20 30 pF1KE0 MIISTPQRLTSSGSVLIGSPYTPAPAMVTQ ..:. ::: ..:. ..::: :. ...: CCDS14 VAVHTSTVNPLGKQLLPKTFGQSSVNIDQQVVIGMPQRPAASNIPVVGSPNPPSTHFASQ 30 40 50 60 70 80 40 50 60 70 80 pF1KE0 T-HIAEATGWVPGDRKRARKFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTS . : . :. .....::.::: :: ..:::: : :::::::: CCDS14 NQHSYSSPPWA-----------------GQHNRKGEKNGMGLCRLSMKVWETVQRKGTTS 90 100 110 120 90 100 110 120 130 140 pF1KE0 YNEVADELVSEFTNSNNHLAAD-SAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGL .::. :::..: ..:: . . :::: :::.::.::::::::::::::.:::.:::::: CCDS14 CQEVVGELVAKFRAASNHASPNESAYDVKNIKRRTYDALNVLMAMNIISREKKKIKWIGL 130 140 150 160 170 180 150 160 170 180 190 200 pF1KE0 PTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPALN :::::.::::..:.:.:.::::::...::.:.:::::::::: ::. :.: . : : CCDS14 TTNSAQNCQNLRVERQKRLERIKQKQSELQQLILQQIAFKNLVLRNQYVEEQVSQRPLPN 190 200 210 220 230 240 210 220 230 240 250 260 pF1KE0 STIQLPFIIINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKC :.:..:::::..:.::::.::::.:: ::::.:...:::::: ::: :::.::::::.: CCDS14 SVIHVPFIIISSSKKTVINCSISDDKSEYLFKFNSSFEIHDDTEVLMWMGMTFGLESGSC 250 260 270 280 290 300 270 280 290 300 310 320 pF1KE0 SLEDLKLAKSLVPKALEGYITDISTGPSWLNQGLLLNSTQSVSNLDLTTGATLPQSSVNQ : ::::.:..::::::: :.:... : . : ..... : :: :. : :.... CCDS14 SAEDLKMARNLVPKALEPYVTEMAQG----TFGGVFTTAGSRSN-----GTWLSASDLTN 310 320 330 340 350 360 330 340 350 360 370 380 pF1KE0 GLCLDAEVALATGQFLAPNSHQSSSAASHCSESRGETPCSFNDEDEEDDEEDSSSPE .: :. :: .::..:. : :: ::: . ..:.:::...:. : CCDS14 ---------IAIGM-LA-----TSSGGSQYSGSRVETP-AVEEEEEEDNNDDDLSENDED 370 380 390 400 CCDS14 D 385 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:33:49 2016 done: Sat Nov 5 04:33:50 2016 Total Scan time: 2.800 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]