FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0932, 411 aa 1>>>pF1KE0932 411 - 411 aa - 411 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.9982+/-0.000424; mu= 12.0655+/- 0.026 mean_var=176.5542+/-37.506, 0's: 0 Z-trim(117.0): 24 B-trim: 875 in 2/54 Lambda= 0.096524 statistics sampled from 28609 (28633) to 28609 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.336), width: 16 Scan time: 8.890 The best scores are: opt bits E(85289) NP_068780 (OMIM: 108985,189967) transcriptional en ( 426) 2784 399.9 6.1e-111 NP_003204 (OMIM: 601714) transcriptional enhancer ( 434) 2137 309.8 8.1e-84 XP_006723491 (OMIM: 601729) PREDICTED: transcripti ( 434) 1608 236.2 1.2e-61 NP_958851 (OMIM: 601714) transcriptional enhancer ( 305) 1529 225.0 2e-58 NP_003205 (OMIM: 603170) transcriptional enhancer ( 435) 1513 222.9 1.2e-57 NP_958849 (OMIM: 601714) transcriptional enhancer ( 391) 1434 211.9 2.2e-54 XP_011525706 (OMIM: 601729) PREDICTED: transcripti ( 441) 1119 168.1 3.9e-41 XP_011525708 (OMIM: 601729) PREDICTED: transcripti ( 228) 687 107.6 3.2e-23 XP_011525707 (OMIM: 601729) PREDICTED: transcripti ( 231) 681 106.8 5.8e-23 XP_006723492 (OMIM: 601729) PREDICTED: transcripti ( 261) 676 106.2 1e-22 NP_001243591 (OMIM: 601729) transcriptional enhanc ( 319) 676 106.2 1.2e-22 XP_005259391 (OMIM: 601729) PREDICTED: transcripti ( 411) 676 106.4 1.4e-22 NP_003589 (OMIM: 601729) transcriptional enhancer ( 447) 676 106.4 1.5e-22 XP_011525705 (OMIM: 601729) PREDICTED: transcripti ( 450) 676 106.4 1.5e-22 NP_001243587 (OMIM: 601729) transcriptional enhanc ( 450) 676 106.4 1.5e-22 NP_001243588 (OMIM: 601729) transcriptional enhanc ( 450) 676 106.4 1.5e-22 NP_001243590 (OMIM: 601729) transcriptional enhanc ( 451) 676 106.4 1.5e-22 NP_001243589 (OMIM: 601729) transcriptional enhanc ( 451) 676 106.4 1.5e-22 XP_006723487 (OMIM: 601729) PREDICTED: transcripti ( 451) 676 106.4 1.5e-22 XP_011525703 (OMIM: 601729) PREDICTED: transcripti ( 454) 676 106.4 1.5e-22 XP_011525701 (OMIM: 601729) PREDICTED: transcripti ( 454) 676 106.4 1.5e-22 XP_011525704 (OMIM: 601729) PREDICTED: transcripti ( 454) 676 106.4 1.5e-22 XP_011525700 (OMIM: 601729) PREDICTED: transcripti ( 454) 676 106.4 1.5e-22 XP_011525702 (OMIM: 601729) PREDICTED: transcripti ( 454) 676 106.4 1.5e-22 >>NP_068780 (OMIM: 108985,189967) transcriptional enhanc (426 aa) initn: 2784 init1: 2784 opt: 2784 Z-score: 2112.8 bits: 399.9 E(85289): 6.1e-111 Smith-Waterman score: 2784; 100.0% identity (100.0% similar) in 411 aa overlap (1-411:16-426) 10 20 30 40 pF1KE0 MERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIIL ::::::::::::::::::::::::::::::::::::::::::::: NP_068 MEPSSWSGSESPAENMERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIIL 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 SDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQTAKDKALQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 SDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQTAKDKALQ 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 HMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDVKPFVQQAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 HMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDVKPFVQQAY 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE0 PIQPAVTAPIPGFEPASAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPDSYNKHLFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 PIQPAVTAPIPGFEPASAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPDSYNKHLFV 190 200 210 220 230 240 230 240 250 260 270 280 pF1KE0 HIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 HIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQD 250 260 270 280 290 300 290 300 310 320 330 340 pF1KE0 DAGAFYGVTSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 DAGAFYGVTSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCE 310 320 330 340 350 360 350 360 370 380 390 400 pF1KE0 YMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 YMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHI 370 380 390 400 410 420 410 pF1KE0 YRLVKD :::::: NP_068 YRLVKD >>NP_003204 (OMIM: 601714) transcriptional enhancer fact (434 aa) initn: 2102 init1: 1953 opt: 2137 Z-score: 1625.7 bits: 309.8 E(85289): 8.1e-84 Smith-Waterman score: 2137; 77.2% identity (90.5% similar) in 412 aa overlap (5-411:28-434) 10 20 30 pF1KE0 MERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPP :.. ::::::::::::::::::::::::::::: NP_003 MEGTAGTITSNEWSSPTSPEGSTASGGSQALDKPIDNDAEGVWSPDIEQSFQEALAIYPP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 CGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQ :::::::::::::::::::::::::::::::::::::::::::::::::.:....::::: NP_003 CGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKAREIQAKLKDQ 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 TAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDV .::::::: :::::::::.::::.:....: : :.. ::: : . :: :.:.:: NP_003 AAKDKALQSMAAMSSAQIISATAFHSSMALA--RGPGRPAVSGFWQGALP-GQAGTSHDV 130 140 150 160 170 160 170 180 190 200 210 pF1KE0 KPFVQQAYPIQPAVTAPIPGFEPASAPAPS-----VPAWQGRSIGTTKLRLVEFSAFLEQ ::: ::.: .:: . :.:::: ..:::: .: :::::....:: ..:::::::: NP_003 KPFSQQTYAVQPPL--PLPGFESPAGPAPSPSAPPAPPWQGRSVASSKLWMLEFSAFLEQ 180 190 200 210 220 230 220 230 240 250 260 270 pF1KE0 QRDPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFL :.:::.::::::::::... ::::: ::.::::::::::::::::::.:: .::.::::: NP_003 QQDPDTYNKHLFVHIGQSSPSYSDPYLEAVDIRQIYDKFPEKKGGLKDLFERGPSNAFFL 240 250 260 270 280 290 280 290 300 310 320 330 pF1KE0 VKFWADLNCNIQDDAGAFYGVTSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENG :::::::: ::.:....::::.::::: ::: .:::::::::::::::::::::::.::: NP_003 VKFWADLNTNIEDEGSSFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENG 300 310 320 330 340 350 340 350 360 370 380 390 pF1KE0 RFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVF .. :::.:::.:::::::::::::::::::::::::::::: :::::::::::::.: :: NP_003 HYSYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVF 360 370 380 390 400 410 400 410 pF1KE0 EVSNSEHGAQHHIYRLVKD ::: ::::::::::::::. NP_003 EVSASEHGAQHHIYRLVKE 420 430 >>XP_006723491 (OMIM: 601729) PREDICTED: transcriptional (434 aa) initn: 1675 init1: 640 opt: 1608 Z-score: 1227.6 bits: 236.2 E(85289): 1.2e-61 Smith-Waterman score: 1677; 64.3% identity (78.5% similar) in 428 aa overlap (5-411:30-434) 10 20 30 pF1KE0 MERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIY :..: ::::::::::::::::::::: XP_006 MGEPRAGAALDDGSGWTGSEEGSEEGTGGSEGAGGDGGPDAEGVWSPDIEQSFQEALAIY 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 PPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::...:::: XP_006 PPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLK 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 DQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAP---GFWPGMIQTGQPG ::..::::.: ::.:::::..:: ... ::: :: : : :: : .: : XP_006 DQVSKDKAFQTMATMSSAQLISAPSLQAKLG------PTGPQASELFQFWSG--GSGPPW 130 140 150 160 170 160 170 180 190 200 pF1KE0 SSQDVKPFVQQAYPIQPAVTAP---IPGFEPASA------PAPSVPAWQGRSIGTTKLRL . ::::: : :. ..: : .::.:: .: :.:: ::::.:..::..:.: XP_006 NVPDVKPFSQT--PFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQL 180 190 200 210 220 230 210 220 230 240 250 260 pF1KE0 VEFSAFLEQQRDPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFG ::::::.: :::..::::::.. : . : :::::.::::::::::::::.::. XP_006 VEFSAFVEPPDAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYD 240 250 260 270 280 290 270 280 290 300 310 pF1KE0 KGPQNAFFLVKFWADLNCNIQ-DDAGA--------FYGVTSQYESSENMTVTCSTKVCSF .:: .:::::::::::: . . ..::: ::::.::::: :.::.:::.: XP_006 RGPPHAFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLTCSSK---- 300 310 320 330 340 320 330 340 350 360 370 pF1KE0 GKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILL :: :..:.::::::. :::::::..::.:::..:::.::::::::::::: XP_006 ---------TERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQ 350 360 370 380 390 380 390 400 410 pF1KE0 VVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD ::::::::: ::: : :::::.::.::::::::::.: XP_006 VVTNRDTQELLLCTAYVFEVSTSERGAQHHIYRLVRD 400 410 420 430 >>NP_958851 (OMIM: 601714) transcriptional enhancer fact (305 aa) initn: 1498 init1: 1349 opt: 1529 Z-score: 1170.0 bits: 225.0 E(85289): 2e-58 Smith-Waterman score: 1529; 73.0% identity (88.1% similar) in 311 aa overlap (107-411:1-305) 80 90 100 110 120 130 pF1KE0 SHIQVLARRKSRDFHSKLKDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLP-GIPRPTF :::::::::.::::.:....: : : NP_958 MAAMSSAQIISATAFHSSMALARG---PGR 10 20 140 150 160 170 180 190 pF1KE0 PGAPGFWPGMIQTGQPGSSQDVKPFVQQAYPIQPAVTAPIPGFEPASAPAPS-----VPA :.. ::: : . :: :.:.::::: ::.: .:: . :.:::: ..:::: .: NP_958 PAVSGFWQGALP-GQAGTSHDVKPFSQQTYAVQPPL--PLPGFESPAGPAPSPSAPPAPP 30 40 50 60 70 80 200 210 220 230 240 250 pF1KE0 WQGRSIGTTKLRLVEFSAFLEQQRDPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDK :::::....:: ..:::::::::.:::.::::::::::... ::::: ::.::::::::: NP_958 WQGRSVASSKLWMLEFSAFLEQQQDPDTYNKHLFVHIGQSSPSYSDPYLEAVDIRQIYDK 90 100 110 120 130 140 260 270 280 290 300 310 pF1KE0 FPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDAGAFYGVTSQYESSENMTVTCSTK :::::::::.:: .::.::::::::::::: ::.:....::::.::::: ::: .::::: NP_958 FPEKKGGLKDLFERGPSNAFFLVKFWADLNTNIEDEGSSFYGVSSQYESPENMIITCSTK 150 160 170 180 190 200 320 330 340 350 360 370 pF1KE0 VCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENF ::::::::::::::::::.:::.. :::.:::.::::::::::::::::::::::::::: NP_958 VCSFGKQVVEKVETEYARYENGHYSYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENF 210 220 230 240 250 260 380 390 400 410 pF1KE0 TILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD ::: :::::::::::::.: ::::: ::::::::::::::. NP_958 TILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVKE 270 280 290 300 >>NP_003205 (OMIM: 603170) transcriptional enhancer fact (435 aa) initn: 1869 init1: 1242 opt: 1513 Z-score: 1156.1 bits: 222.9 E(85289): 1.2e-57 Smith-Waterman score: 2011; 73.1% identity (87.9% similar) in 413 aa overlap (9-411:24-435) 10 20 30 40 pF1KE0 MERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIIL :: .::::::::::::::::::::::::::::::::: NP_003 MASNSWNASSSPGEAREDGPEGLDKGLDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIIL 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 SDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLK----DQTAKD :::::::::::::::::::::::::::::::::::::::.: :... .: ::..:: NP_003 SDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREYQVGIKAMNLDQVSKD 70 80 90 100 110 120 110 120 130 140 150 pF1KE0 KALQHMAAMSSAQIVSATAIHNKLGLPG-IPRPTFPGAPGFWPGMIQTGQ-PGSSQDVKP :::: ::.:::::::::....::.. :. .:. .: . :: . :: :: :::.:: NP_003 KALQSMASMSSAQIVSASVLQNKFSPPSPLPQAVFSTSSRFWSSPPLLGQQPGPSQDIKP 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE0 FVQQAYPIQPAVTAPIPGFEPASAPAPS----VPAWQGRSIGTTKLRLVEFSAFLEQQRD :.: :::::: . . ..:: :: :: ::.:: :.:....:::.:.:::.: ::: NP_003 FAQPAYPIQPPLPPTLSSYEPL-APLPSAAASVPVWQDRTIASSRLRLLEYSAFMEVQRD 190 200 210 220 230 220 230 240 250 260 270 pF1KE0 PDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKF ::.:.::::::::..: ..::: ::.::.:::::::::::::::::. ::: :::::::: NP_003 PDTYSKHLFVHIGQTNPAFSDPPLEAVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKF 240 250 260 270 280 290 280 290 300 310 320 330 pF1KE0 WADLNCNIQDDAGAFYGVTSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFV ::::: .::. ::::::.::: :...::.. :::::::::::::::::::::.:::::: NP_003 WADLNSTIQEGPGAFYGVSSQYSSADSMTISVSTKVCSFGKQVVEKVETEYARLENGRFV 300 310 320 330 340 350 340 350 360 370 380 390 pF1KE0 YRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVS :::.:::::::::::::::::::::::::::::::::: :::.::.::::: .: ::::: NP_003 YRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTSRDSQETLLVIAFVFEVS 360 370 380 390 400 410 400 410 pF1KE0 NSEHGAQHHIYRLVKD .::::::::.:.:::: NP_003 TSEHGAQHHVYKLVKD 420 430 >>NP_958849 (OMIM: 601714) transcriptional enhancer fact (391 aa) initn: 1946 init1: 1284 opt: 1434 Z-score: 1097.2 bits: 211.9 E(85289): 2.2e-54 Smith-Waterman score: 1886; 70.6% identity (81.8% similar) in 412 aa overlap (5-411:28-391) 10 20 30 pF1KE0 MERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPP :.. ::::::::::::::::::::::::::::: NP_958 MEGTAGTITSNEWSSPTSPEGSTASGGSQALDKPIDNDAEGVWSPDIEQSFQEALAIYPP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 CGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQ :::::::::::::::::::::::::::::::::::::::::::::::::.:....::: NP_958 CGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKAREIQAKLK-- 70 80 90 100 110 100 110 120 130 140 150 pF1KE0 TAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDV :: : . :: :.:.:: NP_958 -------------------------------------------FWQGALP-GQAGTSHDV 120 130 160 170 180 190 200 210 pF1KE0 KPFVQQAYPIQPAVTAPIPGFEPASAPAPS-----VPAWQGRSIGTTKLRLVEFSAFLEQ ::: ::.: .:: . :.:::: ..:::: .: :::::....:: ..:::::::: NP_958 KPFSQQTYAVQPPL--PLPGFESPAGPAPSPSAPPAPPWQGRSVASSKLWMLEFSAFLEQ 140 150 160 170 180 190 220 230 240 250 260 270 pF1KE0 QRDPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFL :.:::.::::::::::... ::::: ::.::::::::::::::::::.:: .::.::::: NP_958 QQDPDTYNKHLFVHIGQSSPSYSDPYLEAVDIRQIYDKFPEKKGGLKDLFERGPSNAFFL 200 210 220 230 240 250 280 290 300 310 320 330 pF1KE0 VKFWADLNCNIQDDAGAFYGVTSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENG :::::::: ::.:....::::.::::: ::: .:::::::::::::::::::::::.::: NP_958 VKFWADLNTNIEDEGSSFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENG 260 270 280 290 300 310 340 350 360 370 380 390 pF1KE0 RFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVF .. :::.:::.:::::::::::::::::::::::::::::: :::::::::::::.: :: NP_958 HYSYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVF 320 330 340 350 360 370 400 410 pF1KE0 EVSNSEHGAQHHIYRLVKD ::: ::::::::::::::. NP_958 EVSASEHGAQHHIYRLVKE 380 390 >>XP_011525706 (OMIM: 601729) PREDICTED: transcriptional (441 aa) initn: 1661 init1: 512 opt: 1119 Z-score: 859.5 bits: 168.1 E(85289): 3.9e-41 Smith-Waterman score: 1653; 63.4% identity (77.6% similar) in 429 aa overlap (5-411:30-441) 10 20 30 pF1KE0 MERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIY :..: ::::::::::::::::::::: XP_011 MGEPRAGAALDDGSGWTGSEEGSEEGTGGSEGAGGDGGPDAEGVWSPDIEQSFQEALAIY 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 PPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::...:::: XP_011 PPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLK 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 ----DQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQP ::..::::.: ::.:::::..:: ... ::: : :: : .: : XP_011 ALNVDQVSKDKAFQTMATMSSAQLISAPSLQAKLGPTGPQVVQASELFQFWSG--GSGPP 130 140 150 160 170 160 170 180 190 200 pF1KE0 GSSQDVKPFVQQAYPIQPAVTAP---IPGFEPASA------PAPSVPAWQGRSIGTTKLR . ::::: : :. ..: : .::.:: .: :.:: ::::.:..::..:. XP_011 WNVPDVKPFSQT--PFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQ 180 190 200 210 220 230 210 220 230 240 250 260 pF1KE0 LVEFSAFLEQQRDPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELF :::::::.: :::..::::::.. : . : :::::.::::::::::::::.::. XP_011 LVEFSAFVEPPDAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELY 240 250 260 270 280 290 270 280 290 300 310 pF1KE0 GKGPQNAFFLVKFWADLNCNIQ-DDAGA--------FYGVTSQYESSENMTVTCSTKVCS .:: .:::::::::::: . . ..::: ::::.::::: :.::.:::.: XP_011 DRGPPHAFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLTCSSK--- 300 310 320 330 340 350 320 330 340 350 360 370 pF1KE0 FGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTIL :: :..:.::::::. :::::::..::.:::..:::.::::::::::::: XP_011 ----------TERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTIL 360 370 380 390 400 380 390 400 410 pF1KE0 LVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD ::::::::: ::: : :::::.::.::::::::::.: XP_011 QVVTNRDTQELLLCTAYVFEVSTSERGAQHHIYRLVRD 410 420 430 440 >>XP_011525708 (OMIM: 601729) PREDICTED: transcriptional (228 aa) initn: 657 init1: 512 opt: 687 Z-score: 537.9 bits: 107.6 E(85289): 3.2e-23 Smith-Waterman score: 687; 59.0% identity (71.2% similar) in 212 aa overlap (5-209:30-228) 10 20 30 pF1KE0 MERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIY :..: ::::::::::::::::::::: XP_011 MGEPRAGAALDDGSGWTGSEEGSEEGTGGSEGAGGDGGPDAEGVWSPDIEQSFQEALAIY 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 PPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::...:::: XP_011 PPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLK 70 80 90 100 110 120 100 110 120 130 140 pF1KE0 ----DQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAP---GFWPGMIQT ::..::::.: ::.:::::..:: ... ::: :: : : :: : . XP_011 ALNVDQVSKDKAFQTMATMSSAQLISAPSLQAKLG------PTGPQASELFQFWSG--GS 130 140 150 160 170 150 160 170 180 190 200 pF1KE0 GQPGSSQDVKPFVQQAYPIQPAVTAPIPGFEPASAPAPSVPAWQGRSIGTTKLRLVEFSA : : . ::::: : :. ..: : . :. : .: : : ... : : . XP_011 GPPWNVPDVKPFSQT--PFTLSLTPPSTDL-PGRNSFPEAP--QQISPNVSLARTVSHGH 180 190 200 210 220 210 220 230 240 250 260 pF1KE0 FLEQQRDPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQN : XP_011 F >>XP_011525707 (OMIM: 601729) PREDICTED: transcriptional (231 aa) initn: 661 init1: 512 opt: 681 Z-score: 533.3 bits: 106.8 E(85289): 5.8e-23 Smith-Waterman score: 681; 58.4% identity (70.8% similar) in 209 aa overlap (5-209:30-231) 10 20 30 pF1KE0 MERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIY :..: ::::::::::::::::::::: XP_011 MGEPRAGAALDDGSGWTGSEEGSEEGTGGSEGAGGDGGPDAEGVWSPDIEQSFQEALAIY 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 PPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::...:::: XP_011 PPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLK 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 ----DQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQP ::..::::.: ::.:::::..:: ... ::: : :: : .: : XP_011 ALNVDQVSKDKAFQTMATMSSAQLISAPSLQAKLGPTGPQVVQASELFQFWSG--GSGPP 130 140 150 160 170 160 170 180 190 200 210 pF1KE0 GSSQDVKPFVQQAYPIQPAVTAPIPGFEPASAPAPSVPAWQGRSIGTTKLRLVEFSAFLE . ::::: : :. ..: : . :. : .: : : ... : : . : XP_011 WNVPDVKPFSQT--PFTLSLTPPSTDL-PGRNSFPEAP--QQISPNVSLARTVSHGHF 180 190 200 210 220 230 220 230 240 250 260 270 pF1KE0 QQRDPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFF >>XP_006723492 (OMIM: 601729) PREDICTED: transcriptional (261 aa) initn: 1117 init1: 667 opt: 676 Z-score: 528.9 bits: 106.2 E(85289): 1e-22 Smith-Waterman score: 1107; 68.0% identity (84.6% similar) in 247 aa overlap (174-411:15-261) 150 160 170 180 190 200 pF1KE0 GMIQTGQPGSSQDVKPFVQQAYPIQPAVTAPIPGFEPASAPAPSVPAWQGRSIGTTKLRL : .. : :.:: ::::.:..::..:.: XP_006 MATSNCKGGWERYEPPQALSPLPPPTPSPPAWQARGLGTARLQL 10 20 30 40 210 220 230 240 250 260 pF1KE0 VEFSAFLEQQRDPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFG ::::::.: :::..::::::.. : . : :::::.::::::::::::::.::. XP_006 VEFSAFVEPPDAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYD 50 60 70 80 90 100 270 280 290 300 310 pF1KE0 KGPQNAFFLVKFWADLNCNIQ-DDAGA--------FYGVTSQYESSENMTVTCSTKVCSF .:: .:::::::::::: . . ..::: ::::.::::: :.::.:::.::::: XP_006 RGPPHAFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLTCSSKVCSF 110 120 130 140 150 160 320 330 340 350 360 370 pF1KE0 GKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILL ::::::::::: :..:.::::::. :::::::..::.:::..:::.::::::::::::: XP_006 GKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQ 170 180 190 200 210 220 380 390 400 410 pF1KE0 VVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD ::::::::: ::: : :::::.::.::::::::::.: XP_006 VVTNRDTQELLLCTAYVFEVSTSERGAQHHIYRLVRD 230 240 250 260 411 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:35:06 2016 done: Sat Nov 5 04:35:08 2016 Total Scan time: 8.890 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]