FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0935, 418 aa 1>>>pF1KE0935 418 - 418 aa - 418 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9909+/-0.000709; mu= 22.9571+/- 0.044 mean_var=324.8606+/-66.825, 0's: 0 Z-trim(111.1): 2101 B-trim: 94 in 2/52 Lambda= 0.071158 statistics sampled from 17274 (19631) to 17274 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.553), E-opt: 0.2 (0.23), width: 16 Scan time: 6.330 The best scores are: opt bits E(85289) NP_653291 (OMIM: 615600) zinc finger protein 582 i ( 517) 1791 199.0 2.3e-50 NP_001307300 (OMIM: 615600) zinc finger protein 58 ( 548) 1791 199.0 2.4e-50 NP_001316584 (OMIM: 194528) zinc finger protein 25 ( 455) 1317 150.2 9.9e-36 NP_001316578 (OMIM: 194528) zinc finger protein 25 ( 460) 1309 149.4 1.8e-35 XP_011517656 (OMIM: 194528) PREDICTED: zinc finger ( 460) 1309 149.4 1.8e-35 NP_001316576 (OMIM: 194528) zinc finger protein 25 ( 460) 1309 149.4 1.8e-35 NP_001316577 (OMIM: 194528) zinc finger protein 25 ( 460) 1309 149.4 1.8e-35 NP_001316582 (OMIM: 194528) zinc finger protein 25 ( 456) 1308 149.3 1.9e-35 NP_001316581 (OMIM: 194528) zinc finger protein 25 ( 456) 1308 149.3 1.9e-35 NP_001316583 (OMIM: 194528) zinc finger protein 25 ( 456) 1308 149.3 1.9e-35 NP_659448 (OMIM: 194528) zinc finger protein 25 is ( 456) 1308 149.3 1.9e-35 NP_001316579 (OMIM: 194528) zinc finger protein 25 ( 456) 1308 149.3 1.9e-35 NP_001316580 (OMIM: 194528) zinc finger protein 25 ( 456) 1308 149.3 1.9e-35 NP_689839 (OMIM: 603974) zinc finger protein 92 is ( 586) 1303 149.0 2.9e-35 NP_003432 (OMIM: 194648,615226) zinc finger protei ( 474) 1267 145.1 3.5e-34 XP_016864080 (OMIM: 194648,615226) PREDICTED: zinc ( 534) 1267 145.2 3.7e-34 NP_001278534 (OMIM: 194500) zinc finger protein 2 ( 438) 1263 144.6 4.6e-34 NP_066574 (OMIM: 194500) zinc finger protein 2 iso ( 425) 1260 144.3 5.6e-34 NP_001152765 (OMIM: 603984) zinc finger protein 73 ( 536) 1243 142.8 2e-33 XP_006722660 (OMIM: 603984) PREDICTED: zinc finger ( 550) 1243 142.8 2e-33 XP_011525901 (OMIM: 603984) PREDICTED: zinc finger ( 550) 1243 142.8 2e-33 XP_005259754 (OMIM: 603984) PREDICTED: zinc finger ( 551) 1243 142.8 2.1e-33 XP_011525900 (OMIM: 603984) PREDICTED: zinc finger ( 551) 1243 142.8 2.1e-33 XP_011525788 (OMIM: 608640) PREDICTED: zinc finger ( 436) 1217 139.9 1.2e-32 NP_001309757 (OMIM: 608640) zinc finger protein 46 ( 475) 1217 140.0 1.2e-32 NP_001309755 (OMIM: 608640) zinc finger protein 46 ( 509) 1217 140.0 1.3e-32 NP_001309756 (OMIM: 608640) zinc finger protein 46 ( 509) 1217 140.0 1.3e-32 XP_016882959 (OMIM: 608640) PREDICTED: zinc finger ( 519) 1217 140.1 1.3e-32 NP_001309754 (OMIM: 608640) zinc finger protein 46 ( 532) 1217 140.1 1.3e-32 NP_001309752 (OMIM: 608640) zinc finger protein 46 ( 532) 1217 140.1 1.3e-32 NP_001284552 (OMIM: 608640) zinc finger protein 46 ( 540) 1217 140.1 1.3e-32 NP_001309750 (OMIM: 608640) zinc finger protein 46 ( 557) 1217 140.1 1.3e-32 NP_694989 (OMIM: 608640) zinc finger protein 461 i ( 563) 1217 140.1 1.3e-32 NP_001316586 (OMIM: 194528) zinc finger protein 25 ( 420) 1201 138.2 3.7e-32 XP_011517658 (OMIM: 194528) PREDICTED: zinc finger ( 420) 1201 138.2 3.7e-32 NP_001316591 (OMIM: 194528) zinc finger protein 25 ( 420) 1201 138.2 3.7e-32 NP_001316587 (OMIM: 194528) zinc finger protein 25 ( 420) 1201 138.2 3.7e-32 NP_001316588 (OMIM: 194528) zinc finger protein 25 ( 420) 1201 138.2 3.7e-32 NP_001316593 (OMIM: 194528) zinc finger protein 25 ( 420) 1201 138.2 3.7e-32 NP_001316589 (OMIM: 194528) zinc finger protein 25 ( 420) 1201 138.2 3.7e-32 NP_001316585 (OMIM: 194528) zinc finger protein 25 ( 420) 1201 138.2 3.7e-32 NP_001316592 (OMIM: 194528) zinc finger protein 25 ( 420) 1201 138.2 3.7e-32 NP_001316590 (OMIM: 194528) zinc finger protein 25 ( 420) 1201 138.2 3.7e-32 NP_001287880 (OMIM: 603971) zinc finger protein 91 (1159) 1201 139.2 5.3e-32 XP_016881831 (OMIM: 614275) PREDICTED: zinc finger ( 434) 1180 136.1 1.7e-31 XP_016881832 (OMIM: 614275) PREDICTED: zinc finger ( 434) 1180 136.1 1.7e-31 NP_001035939 (OMIM: 614275) zinc finger protein 56 ( 499) 1180 136.2 1.8e-31 XP_011524814 (OMIM: 614275) PREDICTED: zinc finger ( 499) 1180 136.2 1.8e-31 NP_689690 (OMIM: 614275) zinc finger protein 565 [ ( 499) 1180 136.2 1.8e-31 XP_011524816 (OMIM: 614275) PREDICTED: zinc finger ( 499) 1180 136.2 1.8e-31 >>NP_653291 (OMIM: 615600) zinc finger protein 582 isofo (517 aa) initn: 5571 init1: 1768 opt: 1791 Z-score: 1025.1 bits: 199.0 E(85289): 2.3e-50 Smith-Waterman score: 1791; 58.5% identity (81.3% similar) in 417 aa overlap (1-417:1-417) 10 20 30 40 50 60 pF1KE0 MAQESVMFSDVSVDFSQEEWECLNDDQRDLYRDVMLENYSNLVSMGHSISKPNVISYLEQ :. : .: ::.. ::::::. : :::::::::::.::::::.: ..:::.:::.::: NP_653 MSLGSELFRDVAIVFSQEEWQWLAPAQRDLYRDVMLETYSNLVSLGLAVSKPDVISFLEQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 GKEPWLADRELTRGQWPVLESRCETKKLFLKKEIYEIESTQWEIMEKLTRRDFQCSSFRD :::::...: .. : :::::: .::.:: :...::.:: ::::::.:: ..::::.: NP_653 GKEPWMVERVVSGGLCPVLESRYDTKELFPKQHVYEVESPQWEIMESLTSYGLECSSFQD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 DWECNRQFKKELGSQGGHFNQLVFTHEDLPTLSHHPSFTLQQIINSKKKFCASKEYRKTF :::: :: .. :. ::.:... ::..::...: :.:. : :....: . .. :: : NP_653 DWECRNQFDRQQGNPDRHFHQMIIRHEEMPTFDQHASLTFYQKIHTREKPFGYNKCRKDF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 RHGSQFATHEIIHTIEKPYECKECGKSFRHPSRLTHHQKIHTGKKPFECKECGKTFICGS . . .:. :.: ::::.::::::.:.. ::: .:..::.::::.:::::::.: :: NP_653 WQKELLINHQGIYTNEKPYKCKECGKAFKYGSRLIQHENIHSGKKPYECKECGKAFNSGS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 DLTRHHRIHTGEKPYECKECGKAFSSGSNFTRHQRIHTGEKPYECKECGKAFSSGSNFTQ .. .:.:.::::::::::.: :::: .:.. .::: :::::::.::::::::. :.. NP_653 NFIQHQRVHTGEKPYECKDCEKAFSRSSQLIEHQRTHTGEKPYQCKECGKAFNRISHLKV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 HQRIHTGEKPYECKECGNAFSQSSQLIKHQRIHTGEKPYECKECEKAFRSGSDLTRHQRI : ::::::::: :::::..::. ::::.:: .:::.: :::::: ::: .:: : ::::: NP_653 HYRIHTGEKPYACKECGKTFSHRSQLIQHQTVHTGRKLYECKECGKAFNQGSTLIRHQRI 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 HTGEKPYECKICGKAYSQSSQLISHHRIHTSEKPYEYRECGKNFNYDPQLIQHQNLYW ::::::::::.::::. :::: .:.::::.::::. . ::. :. .: : .. NP_653 HTGEKPYECKVCGKAFRVSSQLKQHQRIHTGEKPYQCKVCGRAFKRVSHLTVHYRIHTGE 370 380 390 400 410 420 NP_653 KPYECKECGKAFSHCSQLIHHQVIHTEKKPYEYKECEKTLSHDSTTVQPQRMHNRETHVN 430 440 450 460 470 480 >>NP_001307300 (OMIM: 615600) zinc finger protein 582 is (548 aa) initn: 5571 init1: 1768 opt: 1791 Z-score: 1024.9 bits: 199.0 E(85289): 2.4e-50 Smith-Waterman score: 1791; 58.5% identity (81.3% similar) in 417 aa overlap (1-417:32-448) 10 20 30 pF1KE0 MAQESVMFSDVSVDFSQEEWECLNDDQRDL :. : .: ::.. ::::::. : :::: NP_001 DPLALPSQDSALPQERNQKEDLSALEILKVMSLGSELFRDVAIVFSQEEWQWLAPAQRDL 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 YRDVMLENYSNLVSMGHSISKPNVISYLEQGKEPWLADRELTRGQWPVLESRCETKKLFL :::::::.::::::.: ..:::.:::.::::::::...: .. : :::::: .::.:: NP_001 YRDVMLETYSNLVSLGLAVSKPDVISFLEQGKEPWMVERVVSGGLCPVLESRYDTKELFP 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 KKEIYEIESTQWEIMEKLTRRDFQCSSFRDDWECNRQFKKELGSQGGHFNQLVFTHEDLP :...::.:: ::::::.:: ..::::.::::: :: .. :. ::.:... ::..: NP_001 KQHVYEVESPQWEIMESLTSYGLECSSFQDDWECRNQFDRQQGNPDRHFHQMIIRHEEMP 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE0 TLSHHPSFTLQQIINSKKKFCASKEYRKTFRHGSQFATHEIIHTIEKPYECKECGKSFRH :...: :.:. : :....: . .. :: : . . .:. :.: ::::.::::::.:.. NP_001 TFDQHASLTFYQKIHTREKPFGYNKCRKDFWQKELLINHQGIYTNEKPYKCKECGKAFKY 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE0 PSRLTHHQKIHTGKKPFECKECGKTFICGSDLTRHHRIHTGEKPYECKECGKAFSSGSNF ::: .:..::.::::.:::::::.: ::.. .:.:.::::::::::.: :::: .:.. NP_001 GSRLIQHENIHSGKKPYECKECGKAFNSGSNFIQHQRVHTGEKPYECKDCEKAFSRSSQL 250 260 270 280 290 300 280 290 300 310 320 330 pF1KE0 TRHQRIHTGEKPYECKECGKAFSSGSNFTQHQRIHTGEKPYECKECGNAFSQSSQLIKHQ .::: :::::::.::::::::. :.. : ::::::::: :::::..::. ::::.:: NP_001 IEHQRTHTGEKPYQCKECGKAFNRISHLKVHYRIHTGEKPYACKECGKTFSHRSQLIQHQ 310 320 330 340 350 360 340 350 360 370 380 390 pF1KE0 RIHTGEKPYECKECEKAFRSGSDLTRHQRIHTGEKPYECKICGKAYSQSSQLISHHRIHT .:::.: :::::: ::: .:: : :::::::::::::::.::::. :::: .:.:::: NP_001 TVHTGRKLYECKECGKAFNQGSTLIRHQRIHTGEKPYECKVCGKAFRVSSQLKQHQRIHT 370 380 390 400 410 420 400 410 pF1KE0 SEKPYEYRECGKNFNYDPQLIQHQNLYW .::::. . ::. :. .: : .. NP_001 GEKPYQCKVCGRAFKRVSHLTVHYRIHTGEKPYECKECGKAFSHCSQLIHHQVIHTEKKP 430 440 450 460 470 480 >>NP_001316584 (OMIM: 194528) zinc finger protein 25 iso (455 aa) initn: 2287 init1: 1289 opt: 1317 Z-score: 762.5 bits: 150.2 E(85289): 9.9e-36 Smith-Waterman score: 1317; 47.4% identity (69.2% similar) in 416 aa overlap (3-414:5-416) 10 20 30 40 50 pF1KE0 MAQESVMFSDVSVDFSQEEWECLNDDQRDLYRDVMLENYSNLVSMGHSISKPNVISYL : : ..:: :.:..:::. :. :: ::.::::::::.:::.:. ..:::.. : NP_001 MNKFQGPVTLKDVIVEFTKEEWKLLTPAQRTLYKDVMLENYSHLVSVGYHVNKPNAVFKL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 EQGKEPWLADRELTRGQWPVLESRCETKKLFLKKEIYEIESTQWEIMEKLTRRDFQCSSF .::::::. . :. . .: : : . . . ... . .. . .: . : NP_001 KQGKEPWILEVEFPHRGFPDLWSIHDLEARYQESQAGNSRNGELTKHQKTHTTEKACEC- 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 RDDWECNRQFKKE---LGSQGGHFNQLVFTHEDL-PTLSHHPSFTLQQIINSKKKFCASK ::.. : .. . : : . . . ..:.. .. .: :... : : NP_001 ---KECGKFFCQKSALIVHQHTHSKGKSYDCDKCGKSFSKNEDLIRHQKIHTRDKTYECK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 EYRKTFRHGSQFATHEIIHTIEKPYECKECGKSFRHPSRLTHHQKIHTGKKPFECKECGK : .: : : :... : :. ::::::..: ::: . .::.::: :::.::::: :::: NP_001 ECKKIFYHLSSLSRHLRTHAGEKPYECNQCEKSFYQKPHLTEHQKTHTGEKPFECTECGK 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 TFICGSDLTRHHRIHTGEKPYECKECGKAFSSGSNFTRHQRIHTGEKPYECKECGKAFSS : . : :.. :::::::::::::::::. :..: :::.:::::::.:::::: :: NP_001 FFYVKAYLMVHQKTHTGEKPYECKECGKAFSQKSHLTVHQRMHTGEKPYKCKECGKFFSR 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 GSNFTQHQRIHTGEKPYECKECGNAFSQSSQLIKHQRIHTGEKPYECKECEKAFRSGSDL .:.. ::: :::::::::::: . : :.: : ::: ::::::.::..: :.: ::: NP_001 NSHLKTHQRSHTGEKPYECKECRKCFYQKSALTVHQRTHTGEKPFECNKCGKTFYYKSDL 300 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 TRHQRIHTGEKPYECKICGKAYSQSSQLISHHRIHTSEKPYEYRECGKNFNYDPQLIQHQ :.::: ::::::::: :::... .: : :.: ::.:::: .::::.:. ..: :: NP_001 TKHQRKHTGEKPYECTECGKSFAVNSVLRLHQRTHTGEKPYACKECGKSFSQKSHFIIHQ 360 370 380 390 400 410 pF1KE0 NLYW NP_001 RKHTGEKPYECQECGETFIQKSQLTAHQKTHTKKRNAEK 420 430 440 450 >>NP_001316578 (OMIM: 194528) zinc finger protein 25 iso (460 aa) initn: 2057 init1: 1059 opt: 1309 Z-score: 758.0 bits: 149.4 E(85289): 1.8e-35 Smith-Waterman score: 1309; 47.5% identity (69.6% similar) in 425 aa overlap (1-414:7-421) 10 20 30 40 50 pF1KE0 MAQESVMFSDVSVDFSQEEWECLNDDQRDLYRDVMLENYSNLVSMGHSISKPNV .:. : ..:: :.:..:::. :. :: ::.::::::::.:::.:. ..:::. NP_001 MWNQPCIARGPVTLKDVIVEFTKEEWKLLTPAQRTLYKDVMLENYSHLVSVGYHVNKPNA 10 20 30 40 50 60 60 70 80 90 100 pF1KE0 ISYLEQGKEPWLADRELT-RG----QWPV--LESRCETKKLFLKKEIYEIESTQWEIMEK . :.::::::. . :. :: : . ::.: . .. ... :. . : . NP_001 VFKLKQGKEPWILEVEFPHRGFPEDLWSIHDLEARYQESQAGNSRN-GELTKHQ---KTH 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 LTRRDFQCSSFRDDWECNRQFKKE---LGSQGGHFNQLVFTHEDL-PTLSHHPSFTLQQI :.. .:. ::.. : .. . : : . . . ..:.. .. .: NP_001 TTEKACECK------ECGKFFCQKSALIVHQHTHSKGKSYDCDKCGKSFSKNEDLIRHQK 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 INSKKKFCASKEYRKTFRHGSQFATHEIIHTIEKPYECKECGKSFRHPSRLTHHQKIHTG :... : :: .: : : :... : :. ::::::..: ::: . .::.::: ::: NP_001 IHTRDKTYECKECKKIFYHLSSLSRHLRTHAGEKPYECNQCEKSFYQKPHLTEHQKTHTG 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 KKPFECKECGKTFICGSDLTRHHRIHTGEKPYECKECGKAFSSGSNFTRHQRIHTGEKPY .::::: :::: : . : :.. :::::::::::::::::. :..: :::.::::::: NP_001 EKPFECTECGKFFYVKAYLMVHQKTHTGEKPYECKECGKAFSQKSHLTVHQRMHTGEKPY 240 250 260 270 280 290 290 300 310 320 330 340 pF1KE0 ECKECGKAFSSGSNFTQHQRIHTGEKPYECKECGNAFSQSSQLIKHQRIHTGEKPYECKE .:::::: :: .:.. ::: :::::::::::: . : :.: : ::: ::::::.::.. NP_001 KCKECGKFFSRNSHLKTHQRSHTGEKPYECKECRKCFYQKSALTVHQRTHTGEKPFECNK 300 310 320 330 340 350 350 360 370 380 390 400 pF1KE0 CEKAFRSGSDLTRHQRIHTGEKPYECKICGKAYSQSSQLISHHRIHTSEKPYEYRECGKN : :.: ::::.::: ::::::::: :::... .: : :.: ::.:::: .::::. NP_001 CGKTFYYKSDLTKHQRKHTGEKPYECTECGKSFAVNSVLRLHQRTHTGEKPYACKECGKS 360 370 380 390 400 410 410 pF1KE0 FNYDPQLIQHQNLYW :. ..: :: NP_001 FSQKSHFIIHQRKHTGEKPYECQECGETFIQKSQLTAHQKTHTKKRNAEK 420 430 440 450 460 >>XP_011517656 (OMIM: 194528) PREDICTED: zinc finger pro (460 aa) initn: 2057 init1: 1059 opt: 1309 Z-score: 758.0 bits: 149.4 E(85289): 1.8e-35 Smith-Waterman score: 1309; 47.5% identity (69.6% similar) in 425 aa overlap (1-414:7-421) 10 20 30 40 50 pF1KE0 MAQESVMFSDVSVDFSQEEWECLNDDQRDLYRDVMLENYSNLVSMGHSISKPNV .:. : ..:: :.:..:::. :. :: ::.::::::::.:::.:. ..:::. XP_011 MWNQPCIARGPVTLKDVIVEFTKEEWKLLTPAQRTLYKDVMLENYSHLVSVGYHVNKPNA 10 20 30 40 50 60 60 70 80 90 100 pF1KE0 ISYLEQGKEPWLADRELT-RG----QWPV--LESRCETKKLFLKKEIYEIESTQWEIMEK . :.::::::. . :. :: : . ::.: . .. ... :. . : . XP_011 VFKLKQGKEPWILEVEFPHRGFPEDLWSIHDLEARYQESQAGNSRN-GELTKHQ---KTH 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 LTRRDFQCSSFRDDWECNRQFKKE---LGSQGGHFNQLVFTHEDL-PTLSHHPSFTLQQI :.. .:. ::.. : .. . : : . . . ..:.. .. .: XP_011 TTEKACECK------ECGKFFCQKSALIVHQHTHSKGKSYDCDKCGKSFSKNEDLIRHQK 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 INSKKKFCASKEYRKTFRHGSQFATHEIIHTIEKPYECKECGKSFRHPSRLTHHQKIHTG :... : :: .: : : :... : :. ::::::..: ::: . .::.::: ::: XP_011 IHTRDKTYECKECKKIFYHLSSLSRHLRTHAGEKPYECNQCEKSFYQKPHLTEHQKTHTG 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 KKPFECKECGKTFICGSDLTRHHRIHTGEKPYECKECGKAFSSGSNFTRHQRIHTGEKPY .::::: :::: : . : :.. :::::::::::::::::. :..: :::.::::::: XP_011 EKPFECTECGKFFYVKAYLMVHQKTHTGEKPYECKECGKAFSQKSHLTVHQRMHTGEKPY 240 250 260 270 280 290 290 300 310 320 330 340 pF1KE0 ECKECGKAFSSGSNFTQHQRIHTGEKPYECKECGNAFSQSSQLIKHQRIHTGEKPYECKE .:::::: :: .:.. ::: :::::::::::: . : :.: : ::: ::::::.::.. XP_011 KCKECGKFFSRNSHLKTHQRSHTGEKPYECKECRKCFYQKSALTVHQRTHTGEKPFECNK 300 310 320 330 340 350 350 360 370 380 390 400 pF1KE0 CEKAFRSGSDLTRHQRIHTGEKPYECKICGKAYSQSSQLISHHRIHTSEKPYEYRECGKN : :.: ::::.::: ::::::::: :::... .: : :.: ::.:::: .::::. XP_011 CGKTFYYKSDLTKHQRKHTGEKPYECTECGKSFAVNSVLRLHQRTHTGEKPYACKECGKS 360 370 380 390 400 410 410 pF1KE0 FNYDPQLIQHQNLYW :. ..: :: XP_011 FSQKSHFIIHQRKHTGEKPYECQECGETFIQKSQLTAHQKTHTKKRNAEK 420 430 440 450 460 >>NP_001316576 (OMIM: 194528) zinc finger protein 25 iso (460 aa) initn: 2057 init1: 1059 opt: 1309 Z-score: 758.0 bits: 149.4 E(85289): 1.8e-35 Smith-Waterman score: 1309; 47.5% identity (69.6% similar) in 425 aa overlap (1-414:7-421) 10 20 30 40 50 pF1KE0 MAQESVMFSDVSVDFSQEEWECLNDDQRDLYRDVMLENYSNLVSMGHSISKPNV .:. : ..:: :.:..:::. :. :: ::.::::::::.:::.:. ..:::. NP_001 MWNQPCIARGPVTLKDVIVEFTKEEWKLLTPAQRTLYKDVMLENYSHLVSVGYHVNKPNA 10 20 30 40 50 60 60 70 80 90 100 pF1KE0 ISYLEQGKEPWLADRELT-RG----QWPV--LESRCETKKLFLKKEIYEIESTQWEIMEK . :.::::::. . :. :: : . ::.: . .. ... :. . : . NP_001 VFKLKQGKEPWILEVEFPHRGFPEDLWSIHDLEARYQESQAGNSRN-GELTKHQ---KTH 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 LTRRDFQCSSFRDDWECNRQFKKE---LGSQGGHFNQLVFTHEDL-PTLSHHPSFTLQQI :.. .:. ::.. : .. . : : . . . ..:.. .. .: NP_001 TTEKACECK------ECGKFFCQKSALIVHQHTHSKGKSYDCDKCGKSFSKNEDLIRHQK 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 INSKKKFCASKEYRKTFRHGSQFATHEIIHTIEKPYECKECGKSFRHPSRLTHHQKIHTG :... : :: .: : : :... : :. ::::::..: ::: . .::.::: ::: NP_001 IHTRDKTYECKECKKIFYHLSSLSRHLRTHAGEKPYECNQCEKSFYQKPHLTEHQKTHTG 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 KKPFECKECGKTFICGSDLTRHHRIHTGEKPYECKECGKAFSSGSNFTRHQRIHTGEKPY .::::: :::: : . : :.. :::::::::::::::::. :..: :::.::::::: NP_001 EKPFECTECGKFFYVKAYLMVHQKTHTGEKPYECKECGKAFSQKSHLTVHQRMHTGEKPY 240 250 260 270 280 290 290 300 310 320 330 340 pF1KE0 ECKECGKAFSSGSNFTQHQRIHTGEKPYECKECGNAFSQSSQLIKHQRIHTGEKPYECKE .:::::: :: .:.. ::: :::::::::::: . : :.: : ::: ::::::.::.. NP_001 KCKECGKFFSRNSHLKTHQRSHTGEKPYECKECRKCFYQKSALTVHQRTHTGEKPFECNK 300 310 320 330 340 350 350 360 370 380 390 400 pF1KE0 CEKAFRSGSDLTRHQRIHTGEKPYECKICGKAYSQSSQLISHHRIHTSEKPYEYRECGKN : :.: ::::.::: ::::::::: :::... .: : :.: ::.:::: .::::. NP_001 CGKTFYYKSDLTKHQRKHTGEKPYECTECGKSFAVNSVLRLHQRTHTGEKPYACKECGKS 360 370 380 390 400 410 410 pF1KE0 FNYDPQLIQHQNLYW :. ..: :: NP_001 FSQKSHFIIHQRKHTGEKPYECQECGETFIQKSQLTAHQKTHTKKRNAEK 420 430 440 450 460 >>NP_001316577 (OMIM: 194528) zinc finger protein 25 iso (460 aa) initn: 2057 init1: 1059 opt: 1309 Z-score: 758.0 bits: 149.4 E(85289): 1.8e-35 Smith-Waterman score: 1309; 47.5% identity (69.6% similar) in 425 aa overlap (1-414:7-421) 10 20 30 40 50 pF1KE0 MAQESVMFSDVSVDFSQEEWECLNDDQRDLYRDVMLENYSNLVSMGHSISKPNV .:. : ..:: :.:..:::. :. :: ::.::::::::.:::.:. ..:::. NP_001 MWNQPCIARGPVTLKDVIVEFTKEEWKLLTPAQRTLYKDVMLENYSHLVSVGYHVNKPNA 10 20 30 40 50 60 60 70 80 90 100 pF1KE0 ISYLEQGKEPWLADRELT-RG----QWPV--LESRCETKKLFLKKEIYEIESTQWEIMEK . :.::::::. . :. :: : . ::.: . .. ... :. . : . NP_001 VFKLKQGKEPWILEVEFPHRGFPEDLWSIHDLEARYQESQAGNSRN-GELTKHQ---KTH 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 LTRRDFQCSSFRDDWECNRQFKKE---LGSQGGHFNQLVFTHEDL-PTLSHHPSFTLQQI :.. .:. ::.. : .. . : : . . . ..:.. .. .: NP_001 TTEKACECK------ECGKFFCQKSALIVHQHTHSKGKSYDCDKCGKSFSKNEDLIRHQK 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 INSKKKFCASKEYRKTFRHGSQFATHEIIHTIEKPYECKECGKSFRHPSRLTHHQKIHTG :... : :: .: : : :... : :. ::::::..: ::: . .::.::: ::: NP_001 IHTRDKTYECKECKKIFYHLSSLSRHLRTHAGEKPYECNQCEKSFYQKPHLTEHQKTHTG 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 KKPFECKECGKTFICGSDLTRHHRIHTGEKPYECKECGKAFSSGSNFTRHQRIHTGEKPY .::::: :::: : . : :.. :::::::::::::::::. :..: :::.::::::: NP_001 EKPFECTECGKFFYVKAYLMVHQKTHTGEKPYECKECGKAFSQKSHLTVHQRMHTGEKPY 240 250 260 270 280 290 290 300 310 320 330 340 pF1KE0 ECKECGKAFSSGSNFTQHQRIHTGEKPYECKECGNAFSQSSQLIKHQRIHTGEKPYECKE .:::::: :: .:.. ::: :::::::::::: . : :.: : ::: ::::::.::.. NP_001 KCKECGKFFSRNSHLKTHQRSHTGEKPYECKECRKCFYQKSALTVHQRTHTGEKPFECNK 300 310 320 330 340 350 350 360 370 380 390 400 pF1KE0 CEKAFRSGSDLTRHQRIHTGEKPYECKICGKAYSQSSQLISHHRIHTSEKPYEYRECGKN : :.: ::::.::: ::::::::: :::... .: : :.: ::.:::: .::::. NP_001 CGKTFYYKSDLTKHQRKHTGEKPYECTECGKSFAVNSVLRLHQRTHTGEKPYACKECGKS 360 370 380 390 400 410 410 pF1KE0 FNYDPQLIQHQNLYW :. ..: :: NP_001 FSQKSHFIIHQRKHTGEKPYECQECGETFIQKSQLTAHQKTHTKKRNAEK 420 430 440 450 460 >>NP_001316582 (OMIM: 194528) zinc finger protein 25 iso (456 aa) initn: 2057 init1: 1059 opt: 1308 Z-score: 757.5 bits: 149.3 E(85289): 1.9e-35 Smith-Waterman score: 1308; 47.8% identity (69.5% similar) in 423 aa overlap (3-414:5-417) 10 20 30 40 50 pF1KE0 MAQESVMFSDVSVDFSQEEWECLNDDQRDLYRDVMLENYSNLVSMGHSISKPNVISYL : : ..:: :.:..:::. :. :: ::.::::::::.:::.:. ..:::.. : NP_001 MNKFQGPVTLKDVIVEFTKEEWKLLTPAQRTLYKDVMLENYSHLVSVGYHVNKPNAVFKL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 EQGKEPWLADRELT-RG----QWPV--LESRCETKKLFLKKEIYEIESTQWEIMEKLTRR .::::::. . :. :: : . ::.: . .. ... :. . : . :.. NP_001 KQGKEPWILEVEFPHRGFPEDLWSIHDLEARYQESQAGNSRN-GELTKHQ---KTHTTEK 70 80 90 100 110 120 130 140 150 160 pF1KE0 DFQCSSFRDDWECNRQFKKE---LGSQGGHFNQLVFTHEDL-PTLSHHPSFTLQQIINSK .:. ::.. : .. . : : . . . ..:.. .. .: :... NP_001 ACECK------ECGKFFCQKSALIVHQHTHSKGKSYDCDKCGKSFSKNEDLIRHQKIHTR 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 KKFCASKEYRKTFRHGSQFATHEIIHTIEKPYECKECGKSFRHPSRLTHHQKIHTGKKPF : :: .: : : :... : :. ::::::..: ::: . .::.::: :::.::: NP_001 DKTYECKECKKIFYHLSSLSRHLRTHAGEKPYECNQCEKSFYQKPHLTEHQKTHTGEKPF 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 ECKECGKTFICGSDLTRHHRIHTGEKPYECKECGKAFSSGSNFTRHQRIHTGEKPYECKE :: :::: : . : :.. :::::::::::::::::. :..: :::.:::::::.::: NP_001 ECTECGKFFYVKAYLMVHQKTHTGEKPYECKECGKAFSQKSHLTVHQRMHTGEKPYKCKE 240 250 260 270 280 290 290 300 310 320 330 340 pF1KE0 CGKAFSSGSNFTQHQRIHTGEKPYECKECGNAFSQSSQLIKHQRIHTGEKPYECKECEKA ::: :: .:.. ::: :::::::::::: . : :.: : ::: ::::::.::..: :. NP_001 CGKFFSRNSHLKTHQRSHTGEKPYECKECRKCFYQKSALTVHQRTHTGEKPFECNKCGKT 300 310 320 330 340 350 350 360 370 380 390 400 pF1KE0 FRSGSDLTRHQRIHTGEKPYECKICGKAYSQSSQLISHHRIHTSEKPYEYRECGKNFNYD : ::::.::: ::::::::: :::... .: : :.: ::.:::: .::::.:. NP_001 FYYKSDLTKHQRKHTGEKPYECTECGKSFAVNSVLRLHQRTHTGEKPYACKECGKSFSQK 360 370 380 390 400 410 410 pF1KE0 PQLIQHQNLYW ..: :: NP_001 SHFIIHQRKHTGEKPYECQECGETFIQKSQLTAHQKTHTKKRNAEK 420 430 440 450 >>NP_001316581 (OMIM: 194528) zinc finger protein 25 iso (456 aa) initn: 2057 init1: 1059 opt: 1308 Z-score: 757.5 bits: 149.3 E(85289): 1.9e-35 Smith-Waterman score: 1308; 47.8% identity (69.5% similar) in 423 aa overlap (3-414:5-417) 10 20 30 40 50 pF1KE0 MAQESVMFSDVSVDFSQEEWECLNDDQRDLYRDVMLENYSNLVSMGHSISKPNVISYL : : ..:: :.:..:::. :. :: ::.::::::::.:::.:. ..:::.. : NP_001 MNKFQGPVTLKDVIVEFTKEEWKLLTPAQRTLYKDVMLENYSHLVSVGYHVNKPNAVFKL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 EQGKEPWLADRELT-RG----QWPV--LESRCETKKLFLKKEIYEIESTQWEIMEKLTRR .::::::. . :. :: : . ::.: . .. ... :. . : . :.. NP_001 KQGKEPWILEVEFPHRGFPEDLWSIHDLEARYQESQAGNSRN-GELTKHQ---KTHTTEK 70 80 90 100 110 120 130 140 150 160 pF1KE0 DFQCSSFRDDWECNRQFKKE---LGSQGGHFNQLVFTHEDL-PTLSHHPSFTLQQIINSK .:. ::.. : .. . : : . . . ..:.. .. .: :... NP_001 ACECK------ECGKFFCQKSALIVHQHTHSKGKSYDCDKCGKSFSKNEDLIRHQKIHTR 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 KKFCASKEYRKTFRHGSQFATHEIIHTIEKPYECKECGKSFRHPSRLTHHQKIHTGKKPF : :: .: : : :... : :. ::::::..: ::: . .::.::: :::.::: NP_001 DKTYECKECKKIFYHLSSLSRHLRTHAGEKPYECNQCEKSFYQKPHLTEHQKTHTGEKPF 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 ECKECGKTFICGSDLTRHHRIHTGEKPYECKECGKAFSSGSNFTRHQRIHTGEKPYECKE :: :::: : . : :.. :::::::::::::::::. :..: :::.:::::::.::: NP_001 ECTECGKFFYVKAYLMVHQKTHTGEKPYECKECGKAFSQKSHLTVHQRMHTGEKPYKCKE 240 250 260 270 280 290 290 300 310 320 330 340 pF1KE0 CGKAFSSGSNFTQHQRIHTGEKPYECKECGNAFSQSSQLIKHQRIHTGEKPYECKECEKA ::: :: .:.. ::: :::::::::::: . : :.: : ::: ::::::.::..: :. NP_001 CGKFFSRNSHLKTHQRSHTGEKPYECKECRKCFYQKSALTVHQRTHTGEKPFECNKCGKT 300 310 320 330 340 350 350 360 370 380 390 400 pF1KE0 FRSGSDLTRHQRIHTGEKPYECKICGKAYSQSSQLISHHRIHTSEKPYEYRECGKNFNYD : ::::.::: ::::::::: :::... .: : :.: ::.:::: .::::.:. NP_001 FYYKSDLTKHQRKHTGEKPYECTECGKSFAVNSVLRLHQRTHTGEKPYACKECGKSFSQK 360 370 380 390 400 410 410 pF1KE0 PQLIQHQNLYW ..: :: NP_001 SHFIIHQRKHTGEKPYECQECGETFIQKSQLTAHQKTHTKKRNAEK 420 430 440 450 >>NP_001316583 (OMIM: 194528) zinc finger protein 25 iso (456 aa) initn: 2057 init1: 1059 opt: 1308 Z-score: 757.5 bits: 149.3 E(85289): 1.9e-35 Smith-Waterman score: 1308; 47.8% identity (69.5% similar) in 423 aa overlap (3-414:5-417) 10 20 30 40 50 pF1KE0 MAQESVMFSDVSVDFSQEEWECLNDDQRDLYRDVMLENYSNLVSMGHSISKPNVISYL : : ..:: :.:..:::. :. :: ::.::::::::.:::.:. ..:::.. : NP_001 MNKFQGPVTLKDVIVEFTKEEWKLLTPAQRTLYKDVMLENYSHLVSVGYHVNKPNAVFKL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 EQGKEPWLADRELT-RG----QWPV--LESRCETKKLFLKKEIYEIESTQWEIMEKLTRR .::::::. . :. :: : . ::.: . .. ... :. . : . :.. NP_001 KQGKEPWILEVEFPHRGFPEDLWSIHDLEARYQESQAGNSRN-GELTKHQ---KTHTTEK 70 80 90 100 110 120 130 140 150 160 pF1KE0 DFQCSSFRDDWECNRQFKKE---LGSQGGHFNQLVFTHEDL-PTLSHHPSFTLQQIINSK .:. ::.. : .. . : : . . . ..:.. .. .: :... NP_001 ACECK------ECGKFFCQKSALIVHQHTHSKGKSYDCDKCGKSFSKNEDLIRHQKIHTR 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 KKFCASKEYRKTFRHGSQFATHEIIHTIEKPYECKECGKSFRHPSRLTHHQKIHTGKKPF : :: .: : : :... : :. ::::::..: ::: . .::.::: :::.::: NP_001 DKTYECKECKKIFYHLSSLSRHLRTHAGEKPYECNQCEKSFYQKPHLTEHQKTHTGEKPF 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 ECKECGKTFICGSDLTRHHRIHTGEKPYECKECGKAFSSGSNFTRHQRIHTGEKPYECKE :: :::: : . : :.. :::::::::::::::::. :..: :::.:::::::.::: NP_001 ECTECGKFFYVKAYLMVHQKTHTGEKPYECKECGKAFSQKSHLTVHQRMHTGEKPYKCKE 240 250 260 270 280 290 290 300 310 320 330 340 pF1KE0 CGKAFSSGSNFTQHQRIHTGEKPYECKECGNAFSQSSQLIKHQRIHTGEKPYECKECEKA ::: :: .:.. ::: :::::::::::: . : :.: : ::: ::::::.::..: :. NP_001 CGKFFSRNSHLKTHQRSHTGEKPYECKECRKCFYQKSALTVHQRTHTGEKPFECNKCGKT 300 310 320 330 340 350 350 360 370 380 390 400 pF1KE0 FRSGSDLTRHQRIHTGEKPYECKICGKAYSQSSQLISHHRIHTSEKPYEYRECGKNFNYD : ::::.::: ::::::::: :::... .: : :.: ::.:::: .::::.:. NP_001 FYYKSDLTKHQRKHTGEKPYECTECGKSFAVNSVLRLHQRTHTGEKPYACKECGKSFSQK 360 370 380 390 400 410 410 pF1KE0 PQLIQHQNLYW ..: :: NP_001 SHFIIHQRKHTGEKPYECQECGETFIQKSQLTAHQKTHTKKRNAEK 420 430 440 450 418 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 20:22:50 2016 done: Sat Nov 5 20:22:51 2016 Total Scan time: 6.330 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]