FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0937, 428 aa 1>>>pF1KE0937 428 - 428 aa - 428 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.9165+/-0.000363; mu= -11.7521+/- 0.023 mean_var=399.2262+/-82.771, 0's: 0 Z-trim(125.1): 149 B-trim: 914 in 2/60 Lambda= 0.064190 statistics sampled from 47806 (47985) to 47806 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.827), E-opt: 0.2 (0.563), width: 16 Scan time: 12.280 The best scores are: opt bits E(85289) NP_001107595 (OMIM: 311040) ETS domain-containing ( 428) 2899 282.0 2e-75 NP_005220 (OMIM: 311040) ETS domain-containing pro ( 428) 2899 282.0 2e-75 XP_016884828 (OMIM: 311040) PREDICTED: ETS domain- ( 428) 2899 282.0 2e-75 XP_005245008 (OMIM: 600246) PREDICTED: ETS domain- ( 431) 701 78.5 3.8e-14 NP_001964 (OMIM: 600246) ETS domain-containing pro ( 431) 701 78.5 3.8e-14 XP_005245007 (OMIM: 600246) PREDICTED: ETS domain- ( 431) 701 78.5 3.8e-14 XP_016856069 (OMIM: 600246) PREDICTED: ETS domain- ( 413) 653 74.0 7.9e-13 NP_001244097 (OMIM: 311040) ETS domain-containing ( 95) 608 69.3 4.6e-12 NP_068567 (OMIM: 600246) ETS domain-containing pro ( 405) 515 61.2 5.5e-09 NP_005221 (OMIM: 600247) ETS domain-containing pro ( 407) 495 59.4 2e-08 XP_006719338 (OMIM: 600247) PREDICTED: ETS domain- ( 407) 495 59.4 2e-08 NP_059991 (OMIM: 607150) protein FEV [Homo sapiens ( 238) 395 49.9 8.1e-06 XP_011533253 (OMIM: 189973) PREDICTED: ETS-related ( 560) 395 50.2 1.6e-05 NP_001138825 (OMIM: 189973) ETS-related transcript ( 595) 395 50.2 1.6e-05 XP_011533252 (OMIM: 189973) PREDICTED: ETS-related ( 619) 395 50.3 1.7e-05 XP_005266334 (OMIM: 189973) PREDICTED: ETS-related ( 619) 395 50.3 1.7e-05 XP_016875901 (OMIM: 189973) PREDICTED: ETS-related ( 619) 395 50.3 1.7e-05 XP_016875898 (OMIM: 189973) PREDICTED: ETS-related ( 619) 395 50.3 1.7e-05 XP_016875902 (OMIM: 189973) PREDICTED: ETS-related ( 619) 395 50.3 1.7e-05 NP_758961 (OMIM: 189973) ETS-related transcription ( 619) 395 50.3 1.7e-05 XP_016875899 (OMIM: 189973) PREDICTED: ETS-related ( 619) 395 50.3 1.7e-05 XP_016875900 (OMIM: 189973) PREDICTED: ETS-related ( 619) 395 50.3 1.7e-05 XP_005266333 (OMIM: 189973) PREDICTED: ETS-related ( 619) 395 50.3 1.7e-05 NP_001248368 (OMIM: 600711) ETS translocation vari ( 207) 380 48.5 1.9e-05 XP_011522816 (OMIM: 600711) PREDICTED: ETS translo ( 221) 380 48.5 2e-05 NP_001248367 (OMIM: 600711) ETS translocation vari ( 445) 380 48.8 3.4e-05 NP_001248366 (OMIM: 600711) ETS translocation vari ( 445) 380 48.8 3.4e-05 XP_016879838 (OMIM: 600711) PREDICTED: ETS translo ( 479) 380 48.8 3.6e-05 NP_001977 (OMIM: 600711) ETS translocation variant ( 484) 380 48.8 3.7e-05 NP_001073143 (OMIM: 600711) ETS translocation vari ( 484) 380 48.8 3.7e-05 NP_001156624 (OMIM: 600541) ETS translocation vari ( 374) 372 48.0 5e-05 NP_001156623 (OMIM: 600541) ETS translocation vari ( 419) 372 48.0 5.5e-05 NP_001156622 (OMIM: 600541) ETS translocation vari ( 437) 372 48.0 5.7e-05 NP_001156619 (OMIM: 600541) ETS translocation vari ( 454) 372 48.0 5.8e-05 NP_001156620 (OMIM: 600541) ETS translocation vari ( 459) 372 48.0 5.9e-05 NP_001156621 (OMIM: 600541) ETS translocation vari ( 459) 372 48.0 5.9e-05 NP_001230358 (OMIM: 165080) transcriptional regula ( 363) 369 47.7 5.9e-05 XP_011513472 (OMIM: 600541) PREDICTED: ETS translo ( 472) 372 48.0 6e-05 XP_005249692 (OMIM: 600541) PREDICTED: ETS translo ( 477) 372 48.0 6e-05 XP_005249693 (OMIM: 600541) PREDICTED: ETS translo ( 477) 372 48.0 6e-05 NP_004947 (OMIM: 600541) ETS translocation variant ( 477) 372 48.0 6e-05 XP_011513470 (OMIM: 600541) PREDICTED: ETS translo ( 477) 372 48.0 6e-05 XP_011513469 (OMIM: 600541) PREDICTED: ETS translo ( 491) 372 48.0 6.2e-05 NP_001129627 (OMIM: 165080) transcriptional regula ( 387) 369 47.7 6.2e-05 XP_016883778 (OMIM: 165080) PREDICTED: transcripti ( 428) 369 47.7 6.7e-05 XP_011527788 (OMIM: 165080) PREDICTED: transcripti ( 435) 369 47.7 6.8e-05 NP_001317954 (OMIM: 165080) transcriptional regula ( 455) 369 47.7 7.1e-05 XP_016883776 (OMIM: 165080) PREDICTED: transcripti ( 459) 369 47.7 7.1e-05 NP_004440 (OMIM: 165080) transcriptional regulator ( 462) 369 47.7 7.2e-05 NP_891548 (OMIM: 165080) transcriptional regulator ( 479) 369 47.8 7.4e-05 >>NP_001107595 (OMIM: 311040) ETS domain-containing prot (428 aa) initn: 2899 init1: 2899 opt: 2899 Z-score: 1475.1 bits: 282.0 E(85289): 2e-75 Smith-Waterman score: 2899; 100.0% identity (100.0% similar) in 428 aa overlap (1-428:1-428) 10 20 30 40 50 60 pF1KE0 MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SRALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQPEVSVTSTMPNVAPAAIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQPEVSVTSTMPNVAPAAIH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 AAPGDTVSGKPGTPKGAGMAGPGGLARSSRNEYMRSGLYSTFTIQSLQPQPPPHPRPAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAPGDTVSGKPGTPKGAGMAGPGGLARSSRNEYMRSGLYSTFTIQSLQPQPPPHPRPAVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LPSAAPAGAAAPPSGSRSTSPSPLEACLEAEEAGLPLQVILTPPEAPNLKSEELNVEPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPSAAPAGAAAPPSGSRSTSPSPLEACLEAEEAGLPLQVILTPPEAPNLKSEELNVEPGL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 GRALPPEVKVEGPKEELEVAGERGFVPETTKAEPEVPPQEGVPARLPAVVMDTAGQAGGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRALPPEVKVEGPKEELEVAGERGFVPETTKAEPEVPPQEGVPARLPAVVMDTAGQAGGH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 AASSPEISQPQKGRKPRDLELPLSPSLLGGPGPERTPGSGSGSGLQAPGPALTPSLLPTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AASSPEISQPQKGRKPRDLELPLSPSLLGGPGPERTPGSGSGSGLQAPGPALTPSLLPTH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 TLTPVLLTPSSLPPSIHFWSTLSPIAPRSPAKLSFQFPSSGSAQVHIPSISVDGLSTPVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLTPVLLTPSSLPPSIHFWSTLSPIAPRSPAKLSFQFPSSGSAQVHIPSISVDGLSTPVV 370 380 390 400 410 420 pF1KE0 LSPGPQKP :::::::: NP_001 LSPGPQKP >>NP_005220 (OMIM: 311040) ETS domain-containing protein (428 aa) initn: 2899 init1: 2899 opt: 2899 Z-score: 1475.1 bits: 282.0 E(85289): 2e-75 Smith-Waterman score: 2899; 100.0% identity (100.0% similar) in 428 aa overlap (1-428:1-428) 10 20 30 40 50 60 pF1KE0 MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SRALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQPEVSVTSTMPNVAPAAIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SRALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQPEVSVTSTMPNVAPAAIH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 AAPGDTVSGKPGTPKGAGMAGPGGLARSSRNEYMRSGLYSTFTIQSLQPQPPPHPRPAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 AAPGDTVSGKPGTPKGAGMAGPGGLARSSRNEYMRSGLYSTFTIQSLQPQPPPHPRPAVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LPSAAPAGAAAPPSGSRSTSPSPLEACLEAEEAGLPLQVILTPPEAPNLKSEELNVEPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LPSAAPAGAAAPPSGSRSTSPSPLEACLEAEEAGLPLQVILTPPEAPNLKSEELNVEPGL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 GRALPPEVKVEGPKEELEVAGERGFVPETTKAEPEVPPQEGVPARLPAVVMDTAGQAGGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GRALPPEVKVEGPKEELEVAGERGFVPETTKAEPEVPPQEGVPARLPAVVMDTAGQAGGH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 AASSPEISQPQKGRKPRDLELPLSPSLLGGPGPERTPGSGSGSGLQAPGPALTPSLLPTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 AASSPEISQPQKGRKPRDLELPLSPSLLGGPGPERTPGSGSGSGLQAPGPALTPSLLPTH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 TLTPVLLTPSSLPPSIHFWSTLSPIAPRSPAKLSFQFPSSGSAQVHIPSISVDGLSTPVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 TLTPVLLTPSSLPPSIHFWSTLSPIAPRSPAKLSFQFPSSGSAQVHIPSISVDGLSTPVV 370 380 390 400 410 420 pF1KE0 LSPGPQKP :::::::: NP_005 LSPGPQKP >>XP_016884828 (OMIM: 311040) PREDICTED: ETS domain-cont (428 aa) initn: 2899 init1: 2899 opt: 2899 Z-score: 1475.1 bits: 282.0 E(85289): 2e-75 Smith-Waterman score: 2899; 100.0% identity (100.0% similar) in 428 aa overlap (1-428:1-428) 10 20 30 40 50 60 pF1KE0 MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SRALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQPEVSVTSTMPNVAPAAIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQPEVSVTSTMPNVAPAAIH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 AAPGDTVSGKPGTPKGAGMAGPGGLARSSRNEYMRSGLYSTFTIQSLQPQPPPHPRPAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAPGDTVSGKPGTPKGAGMAGPGGLARSSRNEYMRSGLYSTFTIQSLQPQPPPHPRPAVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LPSAAPAGAAAPPSGSRSTSPSPLEACLEAEEAGLPLQVILTPPEAPNLKSEELNVEPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPSAAPAGAAAPPSGSRSTSPSPLEACLEAEEAGLPLQVILTPPEAPNLKSEELNVEPGL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 GRALPPEVKVEGPKEELEVAGERGFVPETTKAEPEVPPQEGVPARLPAVVMDTAGQAGGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRALPPEVKVEGPKEELEVAGERGFVPETTKAEPEVPPQEGVPARLPAVVMDTAGQAGGH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 AASSPEISQPQKGRKPRDLELPLSPSLLGGPGPERTPGSGSGSGLQAPGPALTPSLLPTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AASSPEISQPQKGRKPRDLELPLSPSLLGGPGPERTPGSGSGSGLQAPGPALTPSLLPTH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 TLTPVLLTPSSLPPSIHFWSTLSPIAPRSPAKLSFQFPSSGSAQVHIPSISVDGLSTPVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLTPVLLTPSSLPPSIHFWSTLSPIAPRSPAKLSFQFPSSGSAQVHIPSISVDGLSTPVV 370 380 390 400 410 420 pF1KE0 LSPGPQKP :::::::: XP_016 LSPGPQKP >>XP_005245008 (OMIM: 600246) PREDICTED: ETS domain-cont (431 aa) initn: 725 init1: 338 opt: 701 Z-score: 375.0 bits: 78.5 E(85289): 3.8e-14 Smith-Waterman score: 786; 37.4% identity (57.7% similar) in 463 aa overlap (1-427:1-430) 10 20 30 40 50 60 pF1KE0 MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKL :: ..::::::::::.. : :.: ::: :: .:::..:::::::::.:::: ::::::: XP_005 MDSAITLWQFLLQLLQKPQNKHMICWTSNDG-QFKLLQAEEVARLWGIRKNKPNMNYDKL 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 SRALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQPEVSVTSTMPNVAPAAIH :::::::: ::::.::.:::::::::::::. . :. . . .. . . XP_005 SRALRYYYVKNIIKKVNGQKFVYKFVSYPEIL-----NMDPMTVGRIEGDCESLNFSEVS 60 70 80 90 100 110 130 140 150 160 pF1KE0 AAPGDTVSGKPGTPKGAGMAGPGGLARSSRNEYMRSGLYSTFTIQSL------------- .. :. .: : ::. ::::.:..:::::.::..:: XP_005 SSSKDVENGGKDKPPQ-----PGA-KTSSRNDYIHSGLYSSFTLNSLNSSNVKLFKLIKT 120 130 140 150 160 170 180 190 200 210 pF1KE0 --------QPQPPPHPRPAVV----LPSAAPA--GAAAPPSGSRSTSPSPLEACLEAEEA . . : .: :.:. :: : .:: : . : ::: : ..: :. XP_005 ENPAEKLAEKKSPQEPTPSVIKFVTTPSKKPPVEPVAATISIGPSISPSS-EETIQALET 170 180 190 200 210 220 220 230 240 250 260 270 pF1KE0 GLPLQVILTPPEAPNLKSEELNVEPGLGRALPPEVKVEGPKEELEVAGERGFVPETTKAE :. :. :.:.. . . : : .. : .: : : . .. XP_005 -------LVSPKLPSLEAPTSASNVMTAFATTPPISSIPPLQE----PPRTPSPPLS-SH 230 240 250 260 270 280 290 300 310 320 pF1KE0 PEVPPQ-EGV---PARLPAVVMDTAGQAGGHAASSPEISQPQKGRKPRDLELPLSPSLLG :.. . ..: : .:: . . . . .... ....::. ::: .:.:. XP_005 PDIDTDIDSVASQPMELPENLSLEPKDQDSVLLEKDKVNNSSRSKKPKGLEL--APTLVI 280 290 300 310 320 330 330 340 350 360 370 380 pF1KE0 GPGPERTPGSGSGSGLQAPGPALTPSLLPTHTLTPVLLTPSSLPPSIHFWSTLSPIAPRS . : : : : .:::... . ::..:::: : ::::::::::.:: : XP_005 TSSDPSPLGILSPS---LPTASLTPAFF---SQTPIILTPSPLLSSIHFWSTLSPVAPLS 340 350 360 370 380 390 400 410 420 pF1KE0 PAKLS-----FQFPSSGSAQVHIPSISVDGLSTPVVLSPGPQKP ::.:. ::::: ... . ..:: ::: .:: :: XP_005 PARLQGANTLFQFPSVLNSHGPFTLSGLDGPSTPGPFSPDLQKT 390 400 410 420 430 >>NP_001964 (OMIM: 600246) ETS domain-containing protein (431 aa) initn: 725 init1: 338 opt: 701 Z-score: 375.0 bits: 78.5 E(85289): 3.8e-14 Smith-Waterman score: 786; 37.4% identity (57.7% similar) in 463 aa overlap (1-427:1-430) 10 20 30 40 50 60 pF1KE0 MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKL :: ..::::::::::.. : :.: ::: :: .:::..:::::::::.:::: ::::::: NP_001 MDSAITLWQFLLQLLQKPQNKHMICWTSNDG-QFKLLQAEEVARLWGIRKNKPNMNYDKL 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 SRALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQPEVSVTSTMPNVAPAAIH :::::::: ::::.::.:::::::::::::. . :. . . .. . . NP_001 SRALRYYYVKNIIKKVNGQKFVYKFVSYPEIL-----NMDPMTVGRIEGDCESLNFSEVS 60 70 80 90 100 110 130 140 150 160 pF1KE0 AAPGDTVSGKPGTPKGAGMAGPGGLARSSRNEYMRSGLYSTFTIQSL------------- .. :. .: : ::. ::::.:..:::::.::..:: NP_001 SSSKDVENGGKDKPPQ-----PGA-KTSSRNDYIHSGLYSSFTLNSLNSSNVKLFKLIKT 120 130 140 150 160 170 180 190 200 210 pF1KE0 --------QPQPPPHPRPAVV----LPSAAPA--GAAAPPSGSRSTSPSPLEACLEAEEA . . : .: :.:. :: : .:: : . : ::: : ..: :. NP_001 ENPAEKLAEKKSPQEPTPSVIKFVTTPSKKPPVEPVAATISIGPSISPSS-EETIQALET 170 180 190 200 210 220 220 230 240 250 260 270 pF1KE0 GLPLQVILTPPEAPNLKSEELNVEPGLGRALPPEVKVEGPKEELEVAGERGFVPETTKAE :. :. :.:.. . . : : .. : .: : : . .. NP_001 -------LVSPKLPSLEAPTSASNVMTAFATTPPISSIPPLQE----PPRTPSPPLS-SH 230 240 250 260 270 280 290 300 310 320 pF1KE0 PEVPPQ-EGV---PARLPAVVMDTAGQAGGHAASSPEISQPQKGRKPRDLELPLSPSLLG :.. . ..: : .:: . . . . .... ....::. ::: .:.:. NP_001 PDIDTDIDSVASQPMELPENLSLEPKDQDSVLLEKDKVNNSSRSKKPKGLEL--APTLVI 280 290 300 310 320 330 330 340 350 360 370 380 pF1KE0 GPGPERTPGSGSGSGLQAPGPALTPSLLPTHTLTPVLLTPSSLPPSIHFWSTLSPIAPRS . : : : : .:::... . ::..:::: : ::::::::::.:: : NP_001 TSSDPSPLGILSPS---LPTASLTPAFF---SQTPIILTPSPLLSSIHFWSTLSPVAPLS 340 350 360 370 380 390 400 410 420 pF1KE0 PAKLS-----FQFPSSGSAQVHIPSISVDGLSTPVVLSPGPQKP ::.:. ::::: ... . ..:: ::: .:: :: NP_001 PARLQGANTLFQFPSVLNSHGPFTLSGLDGPSTPGPFSPDLQKT 390 400 410 420 430 >>XP_005245007 (OMIM: 600246) PREDICTED: ETS domain-cont (431 aa) initn: 725 init1: 338 opt: 701 Z-score: 375.0 bits: 78.5 E(85289): 3.8e-14 Smith-Waterman score: 786; 37.4% identity (57.7% similar) in 463 aa overlap (1-427:1-430) 10 20 30 40 50 60 pF1KE0 MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKL :: ..::::::::::.. : :.: ::: :: .:::..:::::::::.:::: ::::::: XP_005 MDSAITLWQFLLQLLQKPQNKHMICWTSNDG-QFKLLQAEEVARLWGIRKNKPNMNYDKL 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 SRALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQPEVSVTSTMPNVAPAAIH :::::::: ::::.::.:::::::::::::. . :. . . .. . . XP_005 SRALRYYYVKNIIKKVNGQKFVYKFVSYPEIL-----NMDPMTVGRIEGDCESLNFSEVS 60 70 80 90 100 110 130 140 150 160 pF1KE0 AAPGDTVSGKPGTPKGAGMAGPGGLARSSRNEYMRSGLYSTFTIQSL------------- .. :. .: : ::. ::::.:..:::::.::..:: XP_005 SSSKDVENGGKDKPPQ-----PGA-KTSSRNDYIHSGLYSSFTLNSLNSSNVKLFKLIKT 120 130 140 150 160 170 180 190 200 210 pF1KE0 --------QPQPPPHPRPAVV----LPSAAPA--GAAAPPSGSRSTSPSPLEACLEAEEA . . : .: :.:. :: : .:: : . : ::: : ..: :. XP_005 ENPAEKLAEKKSPQEPTPSVIKFVTTPSKKPPVEPVAATISIGPSISPSS-EETIQALET 170 180 190 200 210 220 220 230 240 250 260 270 pF1KE0 GLPLQVILTPPEAPNLKSEELNVEPGLGRALPPEVKVEGPKEELEVAGERGFVPETTKAE :. :. :.:.. . . : : .. : .: : : . .. XP_005 -------LVSPKLPSLEAPTSASNVMTAFATTPPISSIPPLQE----PPRTPSPPLS-SH 230 240 250 260 270 280 290 300 310 320 pF1KE0 PEVPPQ-EGV---PARLPAVVMDTAGQAGGHAASSPEISQPQKGRKPRDLELPLSPSLLG :.. . ..: : .:: . . . . .... ....::. ::: .:.:. XP_005 PDIDTDIDSVASQPMELPENLSLEPKDQDSVLLEKDKVNNSSRSKKPKGLEL--APTLVI 280 290 300 310 320 330 330 340 350 360 370 380 pF1KE0 GPGPERTPGSGSGSGLQAPGPALTPSLLPTHTLTPVLLTPSSLPPSIHFWSTLSPIAPRS . : : : : .:::... . ::..:::: : ::::::::::.:: : XP_005 TSSDPSPLGILSPS---LPTASLTPAFF---SQTPIILTPSPLLSSIHFWSTLSPVAPLS 340 350 360 370 380 390 400 410 420 pF1KE0 PAKLS-----FQFPSSGSAQVHIPSISVDGLSTPVVLSPGPQKP ::.:. ::::: ... . ..:: ::: .:: :: XP_005 PARLQGANTLFQFPSVLNSHGPFTLSGLDGPSTPGPFSPDLQKT 390 400 410 420 430 >>XP_016856069 (OMIM: 600246) PREDICTED: ETS domain-cont (413 aa) initn: 751 init1: 338 opt: 653 Z-score: 351.3 bits: 74.0 E(85289): 7.9e-13 Smith-Waterman score: 738; 37.4% identity (57.6% similar) in 436 aa overlap (1-400:1-403) 10 20 30 40 50 60 pF1KE0 MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKL :: ..::::::::::.. : :.: ::: :: .:::..:::::::::.:::: ::::::: XP_016 MDSAITLWQFLLQLLQKPQNKHMICWTSNDG-QFKLLQAEEVARLWGIRKNKPNMNYDKL 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 SRALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQPEVSVTSTMPNVAPAAIH :::::::: ::::.::.:::::::::::::. . :. . . .. . . XP_016 SRALRYYYVKNIIKKVNGQKFVYKFVSYPEIL-----NMDPMTVGRIEGDCESLNFSEVS 60 70 80 90 100 110 130 140 150 160 pF1KE0 AAPGDTVSGKPGTPKGAGMAGPGGLARSSRNEYMRSGLYSTFTIQSL------------- .. :. .: : ::. ::::.:..:::::.::..:: XP_016 SSSKDVENGGKDKPPQ-----PGA-KTSSRNDYIHSGLYSSFTLNSLNSSNVKLFKLIKT 120 130 140 150 160 170 180 190 200 210 pF1KE0 --------QPQPPPHPRPAVV----LPSAAPA--GAAAPPSGSRSTSPSPLEACLEAEEA . . : .: :.:. :: : .:: : . : ::: : ..: :. XP_016 ENPAEKLAEKKSPQEPTPSVIKFVTTPSKKPPVEPVAATISIGPSISPSS-EETIQALET 170 180 190 200 210 220 220 230 240 250 260 270 pF1KE0 GLPLQVILTPPEAPNLKSEELNVEPGLGRALPPEVKVEGPKEELEVAGERGFVPETTKAE :. :. :.:.. . . : : .. : .: : : . .. XP_016 -------LVSPKLPSLEAPTSASNVMTAFATTPPISSIPPLQE----PPRTPSPPLS-SH 230 240 250 260 270 280 290 300 310 320 pF1KE0 PEVPPQ-EGV---PARLPAVVMDTAGQAGGHAASSPEISQPQKGRKPRDLELPLSPSLLG :.. . ..: : .:: . . . . .... ....::. ::: .:.:. XP_016 PDIDTDIDSVASQPMELPENLSLEPKDQDSVLLEKDKVNNSSRSKKPKGLEL--APTLVI 280 290 300 310 320 330 330 340 350 360 370 380 pF1KE0 GPGPERTPGSGSGSGLQAPGPALTPSLLPTHTLTPVLLTPSSLPPSIHFWSTLSPIAPRS . : : : : .:::... . ::..:::: : ::::::::::.:: : XP_016 TSSDPSPLGILSPS---LPTASLTPAFF---SQTPIILTPSPLLSSIHFWSTLSPVAPLS 340 350 360 370 380 390 400 410 420 pF1KE0 PAKLS-----FQFPSSGSAQVHIPSISVDGLSTPVVLSPGPQKP ::.:. ::. :: XP_016 PARLQGANTLFQMESSPCHPGWSAVA 390 400 410 >>NP_001244097 (OMIM: 311040) ETS domain-containing prot (95 aa) initn: 607 init1: 607 opt: 608 Z-score: 337.5 bits: 69.3 E(85289): 4.6e-12 Smith-Waterman score: 608; 95.8% identity (97.9% similar) in 95 aa overlap (1-95:1-94) 10 20 30 40 50 60 pF1KE0 MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SRALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQPEVSVTSTMPNVAPAAIH :::::::::::::::::::::::::::::: . :. NP_001 SRALRYYYDKNIIRKVSGQKFVYKFVSYPE-SHCAP 70 80 90 130 140 150 160 170 180 pF1KE0 AAPGDTVSGKPGTPKGAGMAGPGGLARSSRNEYMRSGLYSTFTIQSLQPQPPPHPRPAVV >>NP_068567 (OMIM: 600246) ETS domain-containing protein (405 aa) initn: 594 init1: 338 opt: 515 Z-score: 282.3 bits: 61.2 E(85289): 5.5e-09 Smith-Waterman score: 600; 35.1% identity (56.1% similar) in 399 aa overlap (1-368:1-359) 10 20 30 40 50 60 pF1KE0 MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKL :: ..::::::::::.. : :.: ::: :: .:::..:::::::::.:::: ::::::: NP_068 MDSAITLWQFLLQLLQKPQNKHMICWTSNDG-QFKLLQAEEVARLWGIRKNKPNMNYDKL 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 SRALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQPEVSVTSTMPNVAPAAIH :::::::: ::::.::.:::::::::::::. . :. . . .. . . NP_068 SRALRYYYVKNIIKKVNGQKFVYKFVSYPEIL-----NMDPMTVGRIEGDCESLNFSEVS 60 70 80 90 100 110 130 140 150 160 pF1KE0 AAPGDTVSGKPGTPKGAGMAGPGGLARSSRNEYMRSGLYSTFTIQSL------------- .. :. .: : ::. ::::.:..:::::.::..:: NP_068 SSSKDVENGGKDKPPQ-----PGA-KTSSRNDYIHSGLYSSFTLNSLNSSNVKLFKLIKT 120 130 140 150 160 170 180 190 200 210 pF1KE0 --------QPQPPPHPRPAVV----LPSAAPA--GAAAPPSGSRSTSPSPLEACLEAEEA . . : .: :.:. :: : .:: : . : ::: : ..: :. NP_068 ENPAEKLAEKKSPQEPTPSVIKFVTTPSKKPPVEPVAATISIGPSISPSS-EETIQALET 170 180 190 200 210 220 220 230 240 250 260 270 pF1KE0 GLPLQVILTPPEAPNLKSEELNVEPGLGRALPPEVKVEGPKEELEVAGERGFVPETTKAE :. :. :.:.. . . : : .. : .: : : . .. NP_068 -------LVSPKLPSLEAPTSASNVMTAFATTPPISSIPPLQE----PPRTPSPPLS-SH 230 240 250 260 270 280 290 300 310 320 pF1KE0 PEVPPQ-EGV---PARLPAVVMDTAGQAGGHAASSPEISQPQKGRKPRDLELPLSPSLLG :.. . ..: : .:: . . . . .... ....::. :: :.:.:. NP_068 PDIDTDIDSVASQPMELPENLSLEPKDQDSVLLEKDKVNNSSRSKKPKGLE--LAPTLV- 280 290 300 310 320 330 330 340 350 360 370 380 pF1KE0 GPGPERTPGSGSGSGLQAPGPALTPSLLPTHTLTPVLLTPSSLPPSIHFWSTLSPIAPRS :. .: :.::: :: .:::.... NP_068 -----------ITSSDPSPLGILSPSL-PTASLTPAFFSQVACSLFMVSPLLSFICPFKQ 340 350 360 370 380 390 400 410 420 pF1KE0 PAKLSFQFPSSGSAQVHIPSISVDGLSTPVVLSPGPQKP NP_068 IQNLYTQVCFLLLRFVLERLCVTVM 390 400 >>NP_005221 (OMIM: 600247) ETS domain-containing protein (407 aa) initn: 691 init1: 362 opt: 495 Z-score: 272.3 bits: 59.4 E(85289): 2e-08 Smith-Waterman score: 824; 38.6% identity (59.8% similar) in 438 aa overlap (1-427:1-406) 10 20 30 40 50 60 pF1KE0 MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKL :. ..:::::::::: .: . :.: ::: :: ::::. :::::.:::::::::::::::: NP_005 MESAITLWQFLLQLLLDQKHEHLICWTSNDG-EFKLLKAEEVAKLWGLRKNKTNMNYDKL 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 SRALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQPEVSVTSTMPNVAPAAIH :::::::::::::.:: ::::::::::.::. . : :.: : . . . . NP_005 SRALRYYYDKNIIKKVIGQKFVYKFVSFPEILKMD----PHAVEISRESLL--LQDSDCK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 AAPGDTVSGKPGTPKGAGMAGPGGLARSSRNEYMRSGLYSTFTIQSLQPQPPPHPRPAVV :.: :. . .: . .: .:::::..:::::.:::.::: :: :. NP_005 ASP----EGREAHKHGLA-----ALRSTSRNEYIHSGLYSSFTINSLQ--NPPDAFKAIK 120 130 140 150 160 190 200 210 220 230 240 pF1KE0 LPSAAPAGAAAPPSGSRSTSPSPLEACLEAEEAGLPLQVILTPPEAPNLKSEELNVEPGL . .:: : .. . . . :. : :: . : NP_005 TEKLEEPPEDSPPVEEVRTV---IRFVTNKTDKHVTRPVVSLPST-----SEAAAASAFL 170 180 190 200 210 250 260 270 280 290 pF1KE0 GRALPPEVKVEGPKEELEVAGERGFVPETTKAEPEVP-PQEGVPARLPAVVMDTAGQ--- . .. ... . ... : .. . :. : :.: : :. :. . NP_005 ASSVSAKISSLMLPNAASISSASPFSSRSPSLSPNSPLPSEHRSLFLEAACHDSDSLEPL 220 230 240 250 260 270 300 310 320 330 340 350 pF1KE0 --AGGHAASSPEISQPQKGRKPRDLELPLSPSLLGGPGPERTPGSGSGSGLQAPGPALTP ..: ..:: : : :..::. ::. : .:.: :: . .. :. .::: NP_005 NLSSGSKTKSP--SLPPKAKKPKGLEISAPPLVLSGTDI----GSIALNSPALPSGSLTP 280 290 300 310 320 360 370 380 390 400 pF1KE0 SLLPTHTLTPVLLTPSSLPPSIHFWSTLSPIAPRSPAKLS-----FQFPSSGSAQVHIPS ... ..: . .::::: : ::::::.:::.:: :::.:. ::::. .... .: NP_005 AFFTAQTPNGLLLTPSPLLSSIHFWSSLSPVAPLSPARLQGPSTLFQFPTLLNGHMPVPI 330 340 350 360 370 380 410 420 pF1KE0 ISVDGLSTPVVLSPGPQKP :.: ..::.:: . :: NP_005 PSLDRAASPVLLSSNSQKS 390 400 428 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:36:22 2016 done: Sat Nov 5 04:36:24 2016 Total Scan time: 12.280 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]