FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0941, 268 aa 1>>>pF1KE0941 268 - 268 aa - 268 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.4253+/-0.00109; mu= 3.5810+/- 0.062 mean_var=185.6042+/-42.063, 0's: 0 Z-trim(108.8): 649 B-trim: 197 in 1/49 Lambda= 0.094141 statistics sampled from 9696 (10432) to 9696 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.701), E-opt: 0.2 (0.32), width: 16 Scan time: 2.180 The best scores are: opt bits E(32554) CCDS362.1 TSSK3 gene_id:81629|Hs108|chr1 ( 268) 1825 260.3 9.9e-70 CCDS13755.1 TSSK2 gene_id:23617|Hs108|chr22 ( 358) 893 133.9 1.5e-31 CCDS4112.1 TSSK1B gene_id:83942|Hs108|chr5 ( 367) 866 130.2 2e-30 CCDS12403.1 TSSK6 gene_id:83983|Hs108|chr19 ( 273) 820 123.9 1.2e-28 CCDS73034.1 MARK1 gene_id:4139|Hs108|chr1 ( 780) 665 103.3 5.6e-22 CCDS31029.2 MARK1 gene_id:4139|Hs108|chr1 ( 795) 665 103.3 5.7e-22 CCDS73033.1 MARK1 gene_id:4139|Hs108|chr1 ( 796) 665 103.3 5.7e-22 CCDS55947.1 MARK3 gene_id:4140|Hs108|chr14 ( 713) 644 100.4 3.8e-21 CCDS41993.1 MARK3 gene_id:4140|Hs108|chr14 ( 729) 644 100.4 3.8e-21 CCDS45166.1 MARK3 gene_id:4140|Hs108|chr14 ( 744) 644 100.4 3.9e-21 CCDS45165.1 MARK3 gene_id:4140|Hs108|chr14 ( 753) 644 100.4 3.9e-21 CCDS33575.1 SIK1 gene_id:150094|Hs108|chr21 ( 783) 638 99.6 7.1e-21 CCDS82645.1 LOC102724428 gene_id:102724428|Hs108|c ( 783) 638 99.6 7.1e-21 CCDS53651.1 MARK2 gene_id:2011|Hs108|chr11 ( 709) 634 99.0 9.7e-21 CCDS53650.1 MARK2 gene_id:2011|Hs108|chr11 ( 719) 634 99.0 9.8e-21 CCDS8051.2 MARK2 gene_id:2011|Hs108|chr11 ( 724) 634 99.0 9.8e-21 CCDS41665.1 MARK2 gene_id:2011|Hs108|chr11 ( 745) 634 99.0 1e-20 CCDS53649.1 MARK2 gene_id:2011|Hs108|chr11 ( 788) 634 99.1 1e-20 CCDS60974.1 SIK3 gene_id:23387|Hs108|chr11 (1261) 637 99.7 1.1e-20 CCDS8379.2 SIK3 gene_id:23387|Hs108|chr11 (1321) 637 99.7 1.1e-20 CCDS12658.1 MARK4 gene_id:57787|Hs108|chr19 ( 688) 624 97.6 2.4e-20 CCDS56097.1 MARK4 gene_id:57787|Hs108|chr19 ( 752) 624 97.7 2.6e-20 CCDS8347.1 SIK2 gene_id:23235|Hs108|chr11 ( 926) 623 97.6 3.3e-20 CCDS59123.1 MELK gene_id:9833|Hs108|chr9 ( 610) 598 94.1 2.6e-19 CCDS6606.1 MELK gene_id:9833|Hs108|chr9 ( 651) 598 94.1 2.7e-19 CCDS31892.1 NUAK1 gene_id:9891|Hs108|chr12 ( 661) 591 93.1 5.3e-19 CCDS43075.1 SNRK gene_id:54861|Hs108|chr3 ( 765) 592 93.3 5.3e-19 CCDS12921.1 BRSK1 gene_id:84446|Hs108|chr19 ( 778) 579 91.6 1.8e-18 CCDS3932.2 PRKAA1 gene_id:5562|Hs108|chr5 ( 559) 575 90.9 2.1e-18 CCDS41590.1 BRSK2 gene_id:9024|Hs108|chr11 ( 668) 576 91.1 2.2e-18 CCDS58106.1 BRSK2 gene_id:9024|Hs108|chr11 ( 674) 576 91.1 2.2e-18 CCDS58107.1 BRSK2 gene_id:9024|Hs108|chr11 ( 736) 576 91.2 2.3e-18 CCDS605.1 PRKAA2 gene_id:5563|Hs108|chr1 ( 552) 568 89.9 4.1e-18 CCDS1453.2 NUAK2 gene_id:81788|Hs108|chr1 ( 672) 562 89.2 8.2e-18 CCDS58108.1 BRSK2 gene_id:9024|Hs108|chr11 ( 766) 546 87.1 4e-17 CCDS59126.1 MELK gene_id:9833|Hs108|chr9 ( 619) 536 85.6 8.9e-17 CCDS13610.1 HUNK gene_id:30811|Hs108|chr21 ( 714) 526 84.3 2.5e-16 CCDS60696.1 BRSK2 gene_id:9024|Hs108|chr11 ( 614) 517 83.1 5.3e-16 CCDS3943.1 NIM1K gene_id:167359|Hs108|chr5 ( 436) 510 82.0 8.1e-16 CCDS7092.1 CAMK1D gene_id:57118|Hs108|chr10 ( 357) 500 80.5 1.8e-15 CCDS7091.1 CAMK1D gene_id:57118|Hs108|chr10 ( 385) 500 80.5 1.9e-15 CCDS13843.1 CHEK2 gene_id:11200|Hs108|chr22 ( 543) 497 80.3 3.2e-15 CCDS33629.1 CHEK2 gene_id:11200|Hs108|chr22 ( 586) 497 80.3 3.4e-15 CCDS2582.1 CAMK1 gene_id:8536|Hs108|chr3 ( 370) 491 79.3 4.3e-15 CCDS10851.1 PSKH1 gene_id:5681|Hs108|chr16 ( 424) 490 79.2 5.2e-15 CCDS34076.1 DCLK2 gene_id:166614|Hs108|chr4 ( 766) 486 78.9 1.1e-14 CCDS47142.2 DCLK2 gene_id:166614|Hs108|chr4 ( 783) 486 79.0 1.2e-14 CCDS43064.1 DCLK3 gene_id:85443|Hs108|chr3 ( 648) 484 78.6 1.2e-14 CCDS65789.1 MARK1 gene_id:4139|Hs108|chr1 ( 758) 474 77.3 3.5e-14 CCDS76779.1 ULK3 gene_id:25989|Hs108|chr15 ( 470) 469 76.4 4e-14 >>CCDS362.1 TSSK3 gene_id:81629|Hs108|chr1 (268 aa) initn: 1825 init1: 1825 opt: 1825 Z-score: 1365.4 bits: 260.3 E(32554): 9.9e-70 Smith-Waterman score: 1825; 100.0% identity (100.0% similar) in 268 aa overlap (1-268:1-268) 10 20 30 40 50 60 pF1KE0 MEDFLLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS36 MEDFLLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 IVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS36 IVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 AIRYCHGCGVAHRDLKCENALLQGFNLKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS36 AIRYCHGCGVAHRDLKCENALLQGFNLKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS36 LQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQD 190 200 210 220 230 240 250 260 pF1KE0 LLKRLLEPDMILRPSIEEVSWHPWLAST :::::::::::::::::::::::::::: CCDS36 LLKRLLEPDMILRPSIEEVSWHPWLAST 250 260 >>CCDS13755.1 TSSK2 gene_id:23617|Hs108|chr22 (358 aa) initn: 843 init1: 458 opt: 893 Z-score: 679.7 bits: 133.9 E(32554): 1.5e-31 Smith-Waterman score: 893; 47.4% identity (77.9% similar) in 272 aa overlap (1-265:1-272) 10 20 30 40 50 pF1KE0 MED--FLLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRE :.: : ..:: .: ..:.:.:.::: :.:.. . .::.:.::. : .:..:::::: CCDS13 MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPRE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 LQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQM ..:. :..: .::..::..:..::.: ..:::. ::... . : : :. :. .:::. CCDS13 MDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 VEAIRYCHGCGVAHRDLKCENALL-QGFNLKLTDFGFAK-VLPKSHRE--LSQTFCGSTA :..::: ..:::::::: :: . ::.::.::::.: : :. . ::.:::::.: CCDS13 SSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAA 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 YAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLW-QQQKGVSFPTHLS ::::::::.::.. : :.::.::.::.:.:.:.:.::.:: ::: :... :.:: . CCDS13 YAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKN 190 200 210 220 230 240 240 250 260 pF1KE0 ISADCQDLLKRLLEPDMILRPSIEEVSWHPWLAST .. .:.::. :.:.::. : :.:. : :: CCDS13 LTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQPPKPKATSSASFKREGEGKYRAECKLD 250 260 270 280 290 300 CCDS13 TKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHISGAEVGKAST 310 320 330 340 350 >>CCDS4112.1 TSSK1B gene_id:83942|Hs108|chr5 (367 aa) initn: 825 init1: 447 opt: 866 Z-score: 659.7 bits: 130.2 E(32554): 2e-30 Smith-Waterman score: 866; 47.4% identity (76.5% similar) in 272 aa overlap (1-265:1-272) 10 20 30 40 50 pF1KE0 MED--FLLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRE :.: : :: :: ..:::.:.::: :.:.. . .::::.::. .: .:...::::: CCDS41 MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPRE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 LQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQM ..:. :.: .::..::..:.. ::. .::::: ::... . . : : :..:. :.:. CCDS41 IEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 VEAIRYCHGCGVAHRDLKCENALL-QGFNLKLTDFGFAK--VLPKSHR-ELSQTFCGSTA ::.::: :.::::::.: :: . ::.::.::.:.: . : : ::.::::: : CCDS41 SLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPA 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 YAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLW-QQQKGVSFPTHLS :::::::::::.. : :.::.::.::.:.:.:.:.::..: ::: :... :.:: CCDS41 YAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKH 190 200 210 220 230 240 240 250 260 pF1KE0 ISADCQDLLKRLLEPDMILRPSIEEVSWHPWLAST ....:.::. ..:.::. : :.:. : :. CCDS41 LTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQPKARGSPSVAINKEGESSRGTEPLWTP 250 260 270 280 290 300 CCDS41 EPGSDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFPSKPSTMETEEGPPQQ 310 320 330 340 350 360 >>CCDS12403.1 TSSK6 gene_id:83983|Hs108|chr19 (273 aa) initn: 551 init1: 551 opt: 820 Z-score: 627.6 bits: 123.9 E(32554): 1.2e-28 Smith-Waterman score: 820; 49.2% identity (75.2% similar) in 266 aa overlap (3-265:4-267) 10 20 30 40 50 pF1KE0 MEDFLLSN-GYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRE : :::. ::.::.:::::.::::: : :::.. :::::.:. .: .:...::::: CCDS12 MSGDKLLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 LQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQM :.:.: . : .:..:.:..: .::. .::: : . :... : .: .: .:. :: :. CCDS12 LSILRGVRHPHIVHVFEFIEVCNGKLYIVME-AAATDLLQAVQRNGRIPGVQARDLFAQI 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 VEAIRYCHGCGVAHRDLKCENALLQG--FNLKLTDFGFAKVLPKSHRELSQTFCGSTAYA . :.:: : ..::::::::.::. .:::::::.. ... .:: :.:::.::: CCDS12 AGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGR-QAHGYPDLSTTYCGSAAYA 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 APEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISA .:::: :::.: :: ::::::::::::. . .::::.:: . .:..:: .: : .: CCDS12 SPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQKRGVLYPEGLELSE 180 190 200 210 220 230 240 250 260 pF1KE0 DCQDLLKRLLEPDMILRPSIEEVSWHPWLAST :. :. .::. . ::: .:. . :: CCDS12 RCKALIAELLQFSPSARPSAGQVARNCWLRAGDSG 240 250 260 270 >>CCDS73034.1 MARK1 gene_id:4139|Hs108|chr1 (780 aa) initn: 538 init1: 213 opt: 665 Z-score: 508.1 bits: 103.3 E(32554): 5.6e-22 Smith-Waterman score: 665; 41.2% identity (72.4% similar) in 257 aa overlap (10-265:60-311) 10 20 30 pF1KE0 MEDFLLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIK :.: ::::.:...::: : :.::.: CCDS73 QPTKSSSRQNIPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVK 30 40 50 60 70 80 40 50 60 70 80 90 pF1KE0 VIDKMGGPEEFIQRFLPRELQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDC .::: .:... ::..:.. :.: ::....:..:. . . :::: : ::.::: CCDS73 IIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIET-EKTLYLVMEYASGGEVFDY 90 100 110 120 130 140 100 110 120 130 140 150 pF1KE0 VLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQG-FNLKLTDFGFAKVL .. : . :..:.: :::.: :..::: ..::::: :: ::.: .:.:..::::.. . CCDS73 LVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEF 150 160 170 180 190 200 160 170 180 190 200 210 pF1KE0 PKSHRELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKM ... .::::: :::::..:: .:. . ::::.::.::... .::::: .. .. CCDS73 TVGNK--LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKEL 210 220 230 240 250 260 220 230 240 250 260 pF1KE0 LWQQQKGVSFPTHLSISADCQDLLKRLLEPDMILRPSIEEVSWHPWLAST . .: .. . .:.::..:::.:: . : : :.:.. :. CCDS73 RERVLRG-KYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGHEEEELKPYT 270 280 290 300 310 320 CCDS73 EPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDEVMATYILLGRKPPEFEGGESLSSG 330 340 350 360 370 380 >>CCDS31029.2 MARK1 gene_id:4139|Hs108|chr1 (795 aa) initn: 538 init1: 213 opt: 665 Z-score: 508.0 bits: 103.3 E(32554): 5.7e-22 Smith-Waterman score: 665; 41.2% identity (72.4% similar) in 257 aa overlap (10-265:60-311) 10 20 30 pF1KE0 MEDFLLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIK :.: ::::.:...::: : :.::.: CCDS31 QPTKSSSRQNIPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVK 30 40 50 60 70 80 40 50 60 70 80 90 pF1KE0 VIDKMGGPEEFIQRFLPRELQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDC .::: .:... ::..:.. :.: ::....:..:. . . :::: : ::.::: CCDS31 IIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIET-EKTLYLVMEYASGGEVFDY 90 100 110 120 130 140 100 110 120 130 140 150 pF1KE0 VLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQG-FNLKLTDFGFAKVL .. : . :..:.: :::.: :..::: ..::::: :: ::.: .:.:..::::.. . CCDS31 LVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEF 150 160 170 180 190 200 160 170 180 190 200 210 pF1KE0 PKSHRELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKM ... .::::: :::::..:: .:. . ::::.::.::... .::::: .. .. CCDS31 TVGNK--LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKEL 210 220 230 240 250 260 220 230 240 250 260 pF1KE0 LWQQQKGVSFPTHLSISADCQDLLKRLLEPDMILRPSIEEVSWHPWLAST . .: .. . .:.::..:::.:: . : : :.:.. :. CCDS31 RERVLRG-KYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGHEEEELKPYT 270 280 290 300 310 320 CCDS31 EPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDEVMATYILLGRKPPEFEGGESLSSG 330 340 350 360 370 380 >>CCDS73033.1 MARK1 gene_id:4139|Hs108|chr1 (796 aa) initn: 538 init1: 213 opt: 665 Z-score: 508.0 bits: 103.3 E(32554): 5.7e-22 Smith-Waterman score: 665; 41.2% identity (72.4% similar) in 257 aa overlap (10-265:60-311) 10 20 30 pF1KE0 MEDFLLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIK :.: ::::.:...::: : :.::.: CCDS73 QPTKSSSRQNIPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVK 30 40 50 60 70 80 40 50 60 70 80 90 pF1KE0 VIDKMGGPEEFIQRFLPRELQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDC .::: .:... ::..:.. :.: ::....:..:. . . :::: : ::.::: CCDS73 IIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIET-EKTLYLVMEYASGGEVFDY 90 100 110 120 130 140 100 110 120 130 140 150 pF1KE0 VLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQG-FNLKLTDFGFAKVL .. : . :..:.: :::.: :..::: ..::::: :: ::.: .:.:..::::.. . CCDS73 LVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEF 150 160 170 180 190 200 160 170 180 190 200 210 pF1KE0 PKSHRELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKM ... .::::: :::::..:: .:. . ::::.::.::... .::::: .. .. CCDS73 TVGNK--LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKEL 210 220 230 240 250 260 220 230 240 250 260 pF1KE0 LWQQQKGVSFPTHLSISADCQDLLKRLLEPDMILRPSIEEVSWHPWLAST . .: .. . .:.::..:::.:: . : : :.:.. :. CCDS73 RERVLRG-KYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGHEEEELKPYT 270 280 290 300 310 320 CCDS73 EPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDEVMATYILLGRKPPEFEGGESLSSG 330 340 350 360 370 380 >>CCDS55947.1 MARK3 gene_id:4140|Hs108|chr14 (713 aa) initn: 517 init1: 200 opt: 644 Z-score: 493.1 bits: 100.4 E(32554): 3.8e-21 Smith-Waterman score: 644; 40.1% identity (72.0% similar) in 257 aa overlap (10-265:56-307) 10 20 30 pF1KE0 MEDFLLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIK :.: ::::.:...::: : :.:::: CCDS55 QEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIK 30 40 50 60 70 80 40 50 60 70 80 90 pF1KE0 VIDKMGGPEEFIQRFLPRELQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDC .::: .:... ::..:.. :.: ::....:..:. . . :.:: : ::.::: CCDS55 IIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIET-EKTLYLIMEYASGGEVFDY 90 100 110 120 130 140 100 110 120 130 140 150 pF1KE0 VLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQG-FNLKLTDFGFAKVL .. : . :..:.. :::.: :..::: ..::::: :: ::.. .:.:..::::.. . CCDS55 LVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEF 150 160 170 180 190 200 160 170 180 190 200 210 pF1KE0 PKSHRELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKM . . .::::: :::::..:: .:. . ::::.::.::... .::::: .. .. CCDS55 TVGGK--LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKEL 210 220 230 240 250 260 220 230 240 250 260 pF1KE0 LWQQQKGVSFPTHLSISADCQDLLKRLLEPDMILRPSIEEVSWHPWLAST . .: .. . .:.::..::::.: . : : ..:.. :. CCDS55 RERVLRG-KYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFV 270 280 290 300 310 320 CCDS55 EPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLLGRKSSEVRPSSDLNNS 330 340 350 360 370 380 >>CCDS41993.1 MARK3 gene_id:4140|Hs108|chr14 (729 aa) initn: 517 init1: 200 opt: 644 Z-score: 493.0 bits: 100.4 E(32554): 3.8e-21 Smith-Waterman score: 644; 40.1% identity (72.0% similar) in 257 aa overlap (10-265:56-307) 10 20 30 pF1KE0 MEDFLLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIK :.: ::::.:...::: : :.:::: CCDS41 QEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIK 30 40 50 60 70 80 40 50 60 70 80 90 pF1KE0 VIDKMGGPEEFIQRFLPRELQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDC .::: .:... ::..:.. :.: ::....:..:. . . :.:: : ::.::: CCDS41 IIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIET-EKTLYLIMEYASGGEVFDY 90 100 110 120 130 140 100 110 120 130 140 150 pF1KE0 VLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQG-FNLKLTDFGFAKVL .. : . :..:.. :::.: :..::: ..::::: :: ::.. .:.:..::::.. . CCDS41 LVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEF 150 160 170 180 190 200 160 170 180 190 200 210 pF1KE0 PKSHRELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKM . . .::::: :::::..:: .:. . ::::.::.::... .::::: .. .. CCDS41 TVGGK--LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKEL 210 220 230 240 250 260 220 230 240 250 260 pF1KE0 LWQQQKGVSFPTHLSISADCQDLLKRLLEPDMILRPSIEEVSWHPWLAST . .: .. . .:.::..::::.: . : : ..:.. :. CCDS41 RERVLRG-KYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFV 270 280 290 300 310 320 CCDS41 EPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLLGRKSSELDASDSSSSS 330 340 350 360 370 380 >>CCDS45166.1 MARK3 gene_id:4140|Hs108|chr14 (744 aa) initn: 517 init1: 200 opt: 644 Z-score: 492.9 bits: 100.4 E(32554): 3.9e-21 Smith-Waterman score: 644; 40.1% identity (72.0% similar) in 257 aa overlap (10-265:56-307) 10 20 30 pF1KE0 MEDFLLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIK :.: ::::.:...::: : :.:::: CCDS45 QEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIK 30 40 50 60 70 80 40 50 60 70 80 90 pF1KE0 VIDKMGGPEEFIQRFLPRELQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDC .::: .:... ::..:.. :.: ::....:..:. . . :.:: : ::.::: CCDS45 IIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIET-EKTLYLIMEYASGGEVFDY 90 100 110 120 130 140 100 110 120 130 140 150 pF1KE0 VLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQG-FNLKLTDFGFAKVL .. : . :..:.. :::.: :..::: ..::::: :: ::.. .:.:..::::.. . CCDS45 LVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEF 150 160 170 180 190 200 160 170 180 190 200 210 pF1KE0 PKSHRELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKM . . .::::: :::::..:: .:. . ::::.::.::... .::::: .. .. CCDS45 TVGGK--LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKEL 210 220 230 240 250 260 220 230 240 250 260 pF1KE0 LWQQQKGVSFPTHLSISADCQDLLKRLLEPDMILRPSIEEVSWHPWLAST . .: .. . .:.::..::::.: . : : ..:.. :. CCDS45 RERVLRG-KYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFV 270 280 290 300 310 320 CCDS45 EPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLLGRKSSELDASDSSSSS 330 340 350 360 370 380 268 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:36:57 2016 done: Sat Nov 5 04:36:58 2016 Total Scan time: 2.180 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]