Result of FASTA (ccds) for pF1KE0946
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0946, 367 aa
  1>>>pF1KE0946 367 - 367 aa - 367 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.9302+/-0.00115; mu= 0.3505+/- 0.068
 mean_var=269.0154+/-59.328, 0's: 0 Z-trim(111.7): 625  B-trim: 307 in 1/53
 Lambda= 0.078196
 statistics sampled from 11842 (12590) to 11842 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.741), E-opt: 0.2 (0.387), width:  16
 Scan time:  3.000

The best scores are:                                      opt bits E(32554)
CCDS4112.1 TSSK1B gene_id:83942|Hs108|chr5         ( 367) 2475 292.5   4e-79
CCDS13755.1 TSSK2 gene_id:23617|Hs108|chr22        ( 358) 1597 193.4 2.6e-49
CCDS362.1 TSSK3 gene_id:81629|Hs108|chr1           ( 268)  866 110.8 1.4e-24
CCDS12403.1 TSSK6 gene_id:83983|Hs108|chr19        ( 273)  817 105.3 6.6e-23
CCDS60974.1 SIK3 gene_id:23387|Hs108|chr11         (1261)  702 93.0 1.5e-18
CCDS82645.1 LOC102724428 gene_id:102724428|Hs108|c ( 783)  696 92.1 1.8e-18
CCDS33575.1 SIK1 gene_id:150094|Hs108|chr21        ( 783)  696 92.1 1.8e-18
CCDS8379.2 SIK3 gene_id:23387|Hs108|chr11          (1321)  682 90.7 7.6e-18
CCDS8347.1 SIK2 gene_id:23235|Hs108|chr11          ( 926)  662 88.3 2.8e-17
CCDS73034.1 MARK1 gene_id:4139|Hs108|chr1          ( 780)  648 86.7 7.5e-17
CCDS31029.2 MARK1 gene_id:4139|Hs108|chr1          ( 795)  648 86.7 7.6e-17
CCDS73033.1 MARK1 gene_id:4139|Hs108|chr1          ( 796)  648 86.7 7.6e-17
CCDS53651.1 MARK2 gene_id:2011|Hs108|chr11         ( 709)  645 86.3 8.9e-17
CCDS55947.1 MARK3 gene_id:4140|Hs108|chr14         ( 713)  645 86.3 8.9e-17
CCDS53650.1 MARK2 gene_id:2011|Hs108|chr11         ( 719)  645 86.3 8.9e-17
CCDS8051.2 MARK2 gene_id:2011|Hs108|chr11          ( 724)  645 86.3   9e-17
CCDS41993.1 MARK3 gene_id:4140|Hs108|chr14         ( 729)  645 86.3   9e-17
CCDS45166.1 MARK3 gene_id:4140|Hs108|chr14         ( 744)  645 86.3 9.2e-17
CCDS41665.1 MARK2 gene_id:2011|Hs108|chr11         ( 745)  645 86.3 9.2e-17
CCDS45165.1 MARK3 gene_id:4140|Hs108|chr14         ( 753)  645 86.3 9.2e-17
CCDS53649.1 MARK2 gene_id:2011|Hs108|chr11         ( 788)  645 86.4 9.5e-17
CCDS12658.1 MARK4 gene_id:57787|Hs108|chr19        ( 688)  631 84.7 2.6e-16
CCDS56097.1 MARK4 gene_id:57787|Hs108|chr19        ( 752)  631 84.8 2.8e-16
CCDS43075.1 SNRK gene_id:54861|Hs108|chr3          ( 765)  608 82.2 1.7e-15
CCDS31892.1 NUAK1 gene_id:9891|Hs108|chr12         ( 661)  604 81.6 2.1e-15
CCDS1453.2 NUAK2 gene_id:81788|Hs108|chr1          ( 672)  592 80.3 5.4e-15
CCDS3932.2 PRKAA1 gene_id:5562|Hs108|chr5          ( 559)  579 78.8 1.3e-14
CCDS605.1 PRKAA2 gene_id:5563|Hs108|chr1           ( 552)  574 78.2 1.9e-14
CCDS13610.1 HUNK gene_id:30811|Hs108|chr21         ( 714)  575 78.4 2.1e-14
CCDS41590.1 BRSK2 gene_id:9024|Hs108|chr11         ( 668)  565 77.3 4.4e-14
CCDS58106.1 BRSK2 gene_id:9024|Hs108|chr11         ( 674)  565 77.3 4.5e-14
CCDS58107.1 BRSK2 gene_id:9024|Hs108|chr11         ( 736)  565 77.3 4.7e-14
CCDS12921.1 BRSK1 gene_id:84446|Hs108|chr19        ( 778)  556 76.3   1e-13
CCDS3943.1 NIM1K gene_id:167359|Hs108|chr5         ( 436)  549 75.3 1.1e-13
CCDS58108.1 BRSK2 gene_id:9024|Hs108|chr11         ( 766)  552 75.8 1.3e-13
CCDS59123.1 MELK gene_id:9833|Hs108|chr9           ( 610)  543 74.7 2.3e-13
CCDS6606.1 MELK gene_id:9833|Hs108|chr9            ( 651)  543 74.8 2.4e-13
CCDS2582.1 CAMK1 gene_id:8536|Hs108|chr3           ( 370)  532 73.3 3.9e-13
CCDS60696.1 BRSK2 gene_id:9024|Hs108|chr11         ( 614)  514 71.5 2.3e-12
CCDS1486.1 CAMK1G gene_id:57172|Hs108|chr1         ( 476)  491 68.8 1.1e-11
CCDS13843.1 CHEK2 gene_id:11200|Hs108|chr22        ( 543)  491 68.8 1.2e-11
CCDS33629.1 CHEK2 gene_id:11200|Hs108|chr22        ( 586)  491 68.8 1.3e-11
CCDS59126.1 MELK gene_id:9833|Hs108|chr9           ( 619)  490 68.8 1.5e-11
CCDS65789.1 MARK1 gene_id:4139|Hs108|chr1          ( 758)  475 67.2 5.5e-11
CCDS73254.1 STK33 gene_id:65975|Hs108|chr11        ( 473)  468 66.2 6.9e-11
CCDS7092.1 CAMK1D gene_id:57118|Hs108|chr10        ( 357)  465 65.7 7.1e-11
CCDS7789.1 STK33 gene_id:65975|Hs108|chr11         ( 514)  468 66.2 7.3e-11
CCDS7091.1 CAMK1D gene_id:57118|Hs108|chr10        ( 385)  465 65.7 7.5e-11
CCDS10616.1 PLK1 gene_id:5347|Hs108|chr16          ( 603)  467 66.2 8.8e-11


>>CCDS4112.1 TSSK1B gene_id:83942|Hs108|chr5              (367 aa)
 initn: 2475 init1: 2475 opt: 2475  Z-score: 1534.0  bits: 292.5 E(32554): 4e-79
Smith-Waterman score: 2475; 100.0% identity (100.0% similar) in 367 aa overlap (1-367:1-367)

               10        20        30        40        50        60
pF1KE0 MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPRE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 IEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 IEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 SLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 SLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 YAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 YAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKH
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 LTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQPKARGSPSVAINKEGESSRGTEPLWTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 LTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQPKARGSPSVAINKEGESSRGTEPLWTP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 EPGSDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFPSKPSTMETEEGPPQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 EPGSDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFPSKPSTMETEEGPPQQ
              310       320       330       340       350       360

              
pF1KE0 PPETRAQ
       :::::::
CCDS41 PPETRAQ
              

>>CCDS13755.1 TSSK2 gene_id:23617|Hs108|chr22             (358 aa)
 initn: 1602 init1: 1566 opt: 1597  Z-score: 998.9  bits: 193.4 E(32554): 2.6e-49
Smith-Waterman score: 1597; 71.8% identity (89.4% similar) in 330 aa overlap (1-327:1-330)

               10        20        30        40        50        60
pF1KE0 MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPRE
       ::::.::...::..:::::.:::::::::::::::::::.:::::::.:.::.:.:::::
CCDS13 MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPRE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 IEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQL
       ..::: .:: :::::::::::: :..::.:::.:::::::.:: .:::::: ::: :.::
CCDS13 MDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 SLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPA
       : :.:::::::.:::::::.:::::::::::::::.::::::::..::. :::::::: :
CCDS13 SSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 YAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKH
       ::::::::.::::::::::::::::::::::::::::::.:.:::::::::::.:::::.
CCDS13 YAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKN
              190       200       210       220       230       240

              250       260       270        280       290         
pF1KE0 LTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQP-KARGSPSVAINKEGESSRGTEPLWT
       :: :::::::.::::::..:::::::::: :.:: : ... :.....:::..  .:    
CCDS13 LTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQPPKPKATSSASFKREGEGKYRAECKLD
              250       260       270       280       290       300

     300         310       320       330       340       350       
pF1KE0 PEPG--SDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFPSKPSTMETEEGP
        . :   :..   ::  . . .  . ::..                              
CCDS13 TKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHISGAEVGKAST  
              310       320       330       340       350          

>>CCDS362.1 TSSK3 gene_id:81629|Hs108|chr1                (268 aa)
 initn: 825 init1: 447 opt: 866  Z-score: 554.7  bits: 110.8 E(32554): 1.4e-24
Smith-Waterman score: 866; 47.4% identity (76.5% similar) in 272 aa overlap (1-272:1-265)

               10        20        30        40        50        60
pF1KE0 MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPRE
       :.:   :   :: :: ..:::.:.::: :.:.. . .::::.::.  .: .:...:::::
CCDS36 MED--FLLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRE
                 10        20        30        40        50        

               70        80        90       100       110       120
pF1KE0 IEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQL
       ..:.  :.: .::..::..:.. ::. .:::::  ::... . . : : :..:.  :.:.
CCDS36 LQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQM
       60        70        80        90       100       110        

              130       140       150       160       170       180
pF1KE0 SLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPA
         ::.:::   :.::::::.: :: . ::.::.::.:.:  .   : :  ::.::::: :
CCDS36 VEAIRYCHGCGVAHRDLKCENALL-QGFNLKLTDFGFAK--VLPKSHR-ELSQTFCGSTA
      120       130       140        150         160        170    

              190       200       210       220       230       240
pF1KE0 YAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKH
       :::::::::::.. :  :.::.::.::.:.:.:.:.::..: :::  :... :.::    
CCDS36 YAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLW-QQQKGVSFPTHLS
          180       190       200       210       220        230   

              250       260       270       280       290       300
pF1KE0 LTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQPKARGSPSVAINKEGESSRGTEPLWTP
       ....:.::. ..:.::.  :  :.:.  : :.                            
CCDS36 ISADCQDLLKRLLEPDMILRPSIEEVSWHPWLAST                         
           240       250       260                                 

              310       320       330       340       350       360
pF1KE0 EPGSDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFPSKPSTMETEEGPPQQ

>>CCDS12403.1 TSSK6 gene_id:83983|Hs108|chr19             (273 aa)
 initn: 771 init1: 302 opt: 817  Z-score: 524.8  bits: 105.3 E(32554): 6.6e-23
Smith-Waterman score: 817; 46.2% identity (72.0% similar) in 279 aa overlap (1-278:1-273)

               10        20        30        40        50        60
pF1KE0 MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPRE
       :.   .:.. :: :: ..:::::.::: : :.. : .::::..::..:: ::..::::::
CCDS12 MSGDKLLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 IEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQL
       . ::  . :  :....:..:. .::.::::: :.  :::. ..  : .   .::  : :.
CCDS12 LSILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAAT-DLLQAVQRNGRIPGVQARDLFAQI
               70        80        90        100       110         

              130       140        150       160       170         
pF1KE0 SLAIKYCHDLDVVHRDLKCDNLLLDKDFN-IKLSDFSFSKRCLRDDSGRMALSKTFCGSP
       . :..: ::  .:::::::.:.::. :   .::.::.:.    :.  :   :: :.::: 
CCDS12 AGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFG----RQAHGYPDLSTTYCGSA
     120       130       140       150           160       170     

     180       190       200       210       220       230         
pF1KE0 AYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSK
       :::.:::: ::::.:: ::.::.::.::.:: : ::.:::.:  . : ::.  : .:.. 
CCDS12 AYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQKRG-VLYPEGL
         180       190       200       210       220        230    

     240       250       260       270       280       290         
pF1KE0 HLTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQPKARGSPSVAINKEGESSRGTEPLWT
       .:. .:: :: ..:: . . :    ..  .::..    :                     
CCDS12 ELSERCKALIAELLQFSPSARPSAGQVARNCWLRAGDSG                     
          240       250       260       270                        

     300       310       320       330       340       350         
pF1KE0 PEPGSDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFPSKPSTMETEEGPPQ

>>CCDS60974.1 SIK3 gene_id:23387|Hs108|chr11              (1261 aa)
 initn: 657 init1: 245 opt: 702  Z-score: 446.3  bits: 93.0 E(32554): 1.5e-18
Smith-Waterman score: 707; 38.2% identity (65.4% similar) in 356 aa overlap (9-340:62-404)

                                     10         20        30       
pF1KE0                       MDDAAVLKRRGYL-LGINLGEGSYAKVKSAYSERLKFN
                                     : ::  .  ..:.:..: :: :     : .
CCDS60 PGSPAAPAAVSPAAGQPRPPAPASRGPMPARIGYYEIDRTIGKGNFAVVKRATHLVTKAK
              40        50        60        70        80        90 

        40        50        60        70        80        90       
pF1KE0 VAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGD
       :::::::. .   . :.:.. ::..:. :: :  ::. :...:: .  .:.: : :  :.
CCDS60 VAIKIIDKTQLDEENLKKIF-REVQIMKMLCHPHIIRLYQVMETER-MIYLVTEYASGGE
             100       110        120       130        140         

       100       110       120       130       140       150       
pF1KE0 LLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSF
       ... . ..: . : :::.::.:.  :. .::  ..:::::: .::::: ..:::..::.:
CCDS60 IFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGF
     150       160       170       180       190       200         

       160       170       180       190        200       210      
pF1KE0 SKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQ-PKVYDIWSLGVILYIMVCGSMPY
       :.       :.  : ::.:::: :::::...:  :. ::: :::::::.::..:::..:.
CCDS60 SNLFT---PGQ--LLKTWCGSPPYAAPELFEGKEYDGPKV-DIWSLGVVLYVLVCGALPF
     210            220       230       240        250       260   

        220         230       240       250       260       270    
pF1KE0 DDSNIKKM-LRIQK-EHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQP
       : :.....  :. . . :. :     .. ::. :: :::  : :.:: ...: .: ::. 
CCDS60 DGSTLQNLRARVLSGKFRIPF----FMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMK-
           270       280           290       300       310         

          280           290             300       310           320
pF1KE0 KARGSPS----VAINKEGESSRGTEPL------WTPEPGSDKKSATKLEPEGEAQ----P
        . ..:.    .:  .. .  : ..::         . : ::... . :  : :.    :
CCDS60 LGDADPNFDRLIAECQQLKEERQVDPLNEDVLLAMEDMGLDKEQTLQAEQAGTAMNISVP
      320       330       340       350       360       370        

                    330       340       350       360              
pF1KE0 QAQ---PETK---PEGTAMQMSRQSEILGFPSKPSTMETEEGPPQQPPETRAQ       
       :.:   ::..   :.::    : ..:                                  
CCDS60 QVQLINPENQIVEPDGTLNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKL
      380       390       400       410       420       430        

>>CCDS82645.1 LOC102724428 gene_id:102724428|Hs108|chr21  (783 aa)
 initn: 730 init1: 263 opt: 696  Z-score: 445.3  bits: 92.1 E(32554): 1.8e-18
Smith-Waterman score: 696; 43.5% identity (68.8% similar) in 276 aa overlap (18-291:33-299)

                            10        20        30        40       
pF1KE0              MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKK
                                     ::.:..: :: :  .  : .:::::::. .
CCDS82 IMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTR
             10        20        30        40        50        60  

        50        60        70        80        90       100       
pF1KE0 APADFLEKFLPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGA
         .. :::.  ::.... .:::  ::: :...::.   .::: :.: .:.... . . : 
CCDS82 LDSSNLEKIY-REVQLMKLLNHPHIIKLYQVMETKD-MLYIVTEFAKNGEMFDYLTSNGH
             70         80        90        100       110       120

       110       120       130       140       150       160       
pF1KE0 LHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSG
       : :.:::::: :.  :..::::  .:::::: .::::: ...:::.::.:..      ::
CCDS82 LSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFGN---FYKSG
              130       140       150       160       170          

       170       180       190       200       210       220       
pF1KE0 RMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRI
       .  :: :.:::: ::::::..:  :.    :::::::.::..::::.:.:  :.  . . 
CCDS82 E-PLS-TWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQR
        180        190       200       210       220       230     

       230       240       250       260       270         280     
pF1KE0 QKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWM--QPKARGSPSVAIN
         : :  .:    .. .:..:: .::  :  ::. : .: .: ::  .:   :    :..
CCDS82 VLEGRFRIPF--FMSQDCESLIRRMLVVDPARRITIAQIRQHRWMRAEPCLPGPACPAFS
         240         250       260       270       280       290   

         290       300       310       320       330       340     
pF1KE0 KEGESSRGTEPLWTPEPGSDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFP
        .. .:                                                      
CCDS82 AHSYTSNLGDYDEQALGIMQTLGVDRQRTVESLQNSSYNHFAAIYYLLLERLKEYRNAQC
           300       310       320       330       340       350   

>>CCDS33575.1 SIK1 gene_id:150094|Hs108|chr21             (783 aa)
 initn: 730 init1: 263 opt: 696  Z-score: 445.3  bits: 92.1 E(32554): 1.8e-18
Smith-Waterman score: 696; 43.5% identity (68.8% similar) in 276 aa overlap (18-291:33-299)

                            10        20        30        40       
pF1KE0              MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKK
                                     ::.:..: :: :  .  : .:::::::. .
CCDS33 IMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTR
             10        20        30        40        50        60  

        50        60        70        80        90       100       
pF1KE0 APADFLEKFLPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGA
         .. :::.  ::.... .:::  ::: :...::.   .::: :.: .:.... . . : 
CCDS33 LDSSNLEKIY-REVQLMKLLNHPHIIKLYQVMETKD-MLYIVTEFAKNGEMFDYLTSNGH
             70         80        90        100       110       120

       110       120       130       140       150       160       
pF1KE0 LHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSG
       : :.:::::: :.  :..::::  .:::::: .::::: ...:::.::.:..      ::
CCDS33 LSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFGN---FYKSG
              130       140       150       160       170          

       170       180       190       200       210       220       
pF1KE0 RMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRI
       .  :: :.:::: ::::::..:  :.    :::::::.::..::::.:.:  :.  . . 
CCDS33 E-PLS-TWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQR
        180        190       200       210       220       230     

       230       240       250       260       270         280     
pF1KE0 QKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWM--QPKARGSPSVAIN
         : :  .:    .. .:..:: .::  :  ::. : .: .: ::  .:   :    :..
CCDS33 VLEGRFRIPF--FMSQDCESLIRRMLVVDPARRITIAQIRQHRWMRAEPCLPGPACPAFS
         240         250       260       270       280       290   

         290       300       310       320       330       340     
pF1KE0 KEGESSRGTEPLWTPEPGSDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFP
        .. .:                                                      
CCDS33 AHSYTSNLGDYDEQALGIMQTLGVDRQRTVESLQNSSYNHFAAIYYLLLERLKEYRNAQC
           300       310       320       330       340       350   

>>CCDS8379.2 SIK3 gene_id:23387|Hs108|chr11               (1321 aa)
 initn: 682 init1: 245 opt: 682  Z-score: 433.9  bits: 90.7 E(32554): 7.6e-18
Smith-Waterman score: 682; 42.8% identity (70.6% similar) in 269 aa overlap (9-273:62-318)

                                     10         20        30       
pF1KE0                       MDDAAVLKRRGYL-LGINLGEGSYAKVKSAYSERLKFN
                                     : ::  .  ..:.:..: :: :     : .
CCDS83 PGSPAAPAAVSPAAGQPRPPAPASRGPMPARIGYYEIDRTIGKGNFAVVKRATHLVTKAK
              40        50        60        70        80        90 

        40        50        60        70        80        90       
pF1KE0 VAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGD
       :::::::. .   . :.:.. ::..:. :: :  ::. :...:: .  .:.: : :  :.
CCDS83 VAIKIIDKTQLDEENLKKIF-REVQIMKMLCHPHIIRLYQVMETER-MIYLVTEYASGGE
             100       110        120       130        140         

       100       110       120       130       140       150       
pF1KE0 LLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSF
       ... . ..: . : :::.::.:.  :. .::  ..:::::: .::::: ..:::..::.:
CCDS83 IFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGF
     150       160       170       180       190       200         

       160       170       180       190        200       210      
pF1KE0 SKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQ-PKVYDIWSLGVILYIMVCGSMPY
       :.       :.  : ::.:::: :::::...:  :. ::: :::::::.::..:::..:.
CCDS83 SNLF---TPGQ--LLKTWCGSPPYAAPELFEGKEYDGPKV-DIWSLGVVLYVLVCGALPF
     210            220       230       240        250       260   

        220         230       240       250       260       270    
pF1KE0 DDSNIKKM-LRIQK-EHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQP
       : :.....  :. . . :. :     .. ::. :: :::  : :.:: ...: .: ::. 
CCDS83 DGSTLQNLRARVLSGKFRIPF----FMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMKL
           270       280           290       300       310         

          280       290       300       310       320       330    
pF1KE0 KARGSPSVAINKEGESSRGTEPLWTPEPGSDKKSATKLEPEGEAQPQAQPETKPEGTAMQ
                                                                   
CCDS83 GDADPNFDRLIAECQQLKEERQVDPLNEDVLLAMEDMGLDKEQTLQSLRSDAYDHYSAIY
     320       330       340       350       360       370         

>>CCDS8347.1 SIK2 gene_id:23235|Hs108|chr11               (926 aa)
 initn: 762 init1: 247 opt: 662  Z-score: 423.6  bits: 88.3 E(32554): 2.8e-17
Smith-Waterman score: 662; 43.1% identity (70.2% similar) in 255 aa overlap (18-272:26-271)

                       10        20        30        40        50  
pF1KE0         MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADF
                                ::.:..: :: .  .  : .:::::::...  :  
CCDS83 MVMADGPRHLQRGPVRVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVN
               10        20        30        40        50        60

             60        70        80        90       100       110  
pF1KE0 LEKFLPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDE
       ::: . ::..:. ::.:  ::: :...::. . .:.: : : .:.... . ..: :.:.:
CCDS83 LEK-IYREVQIMKMLDHPHIIKLYQVMETK-SMLYLVTEYAKNGEIFDYLANHGRLNESE
                70        80         90       100       110        

            120       130       140       150       160       170  
pF1KE0 ARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALS
       ::.:: :.  :. :::   .:::::: .:::::...:::..::.:..      ::.  : 
CCDS83 ARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFF---KSGE--LL
      120       130       140       150       160          170     

            180       190       200       210       220       230  
pF1KE0 KTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHR
        :.:::: ::::::..:  :.    ::::.::.::..:::..:.:  ..  . .   : :
CCDS83 ATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGR
           180       190       200       210       220       230   

            240       250       260       270       280       290  
pF1KE0 VNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQPKARGSPSVAINKEGESSR
         .:    .. .:. :: .::  : ..:: : .:  : ::                    
CCDS83 FRIPY--FMSEDCEHLIRRMLVLDPSKRLTIAQIKEHKWMLIEVPVQRPVLYPQEQENEP
             240       250       260       270       280       290 

            300       310       320       330       340       350  
pF1KE0 GTEPLWTPEPGSDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFPSKPSTME
                                                                   
CCDS83 SIGEFNEQVLRLMHSLGIDQQKTIESLQNKSYNHFAAIYFLLVERLKSHRSSFPVEQRLD
             300       310       320       330       340       350 

>>CCDS73034.1 MARK1 gene_id:4139|Hs108|chr1               (780 aa)
 initn: 606 init1: 258 opt: 648  Z-score: 416.0  bits: 86.7 E(32554): 7.5e-17
Smith-Waterman score: 648; 39.9% identity (70.3% similar) in 263 aa overlap (12-272:60-311)

                                  10        20        30        40 
pF1KE0                    MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIK
                                     : :  ..:.:..:::: :       .::.:
CCDS73 QPTKSSSRQNIPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVK
      30        40        50        60        70        80         

              50        60        70        80        90       100 
pF1KE0 IIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLEL
       :::. .     :.:.. ::..:. .::: .:.: .:..:: .  .:.::: :  :.... 
CCDS73 IIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIETEK-TLYLVMEYASGGEVFDY
      90       100        110       120       130        140       

             110       120       130       140       150       160 
pF1KE0 IKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRC
       . ..: ..: ::: ::.:.  :..:::.  .:::::: .::::: :.:::..::.::.. 
CCDS73 LVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEF
       150       160       170       180       190       200       

             170       180       190       200       210       220 
pF1KE0 LRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNI
          ..       :::::: :::::..::  :.    :.:::::::: .: ::.:.: .:.
CCDS73 TVGNK-----LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNL
       210            220       230       240       250       260  

               230       240       250       260       270         
pF1KE0 KKML-RIQK-EHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQPKARGS
       :..  :. . ..:. :    ... .:..:. ..:  .  .:  ...:..  ::       
CCDS73 KELRERVLRGKYRIPF----YMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGHEEE
            270           280       290       300       310        

     280       290       300       310       320       330         
pF1KE0 PSVAINKEGESSRGTEPLWTPEPGSDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQS
                                                                   
CCDS73 ELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDEVMATYILLGRKPPEFEGG
      320       330       340       350       360       370        




367 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 04:39:53 2016 done: Sat Nov  5 04:39:53 2016
 Total Scan time:  3.000 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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