FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0947, 385 aa 1>>>pF1KE0947 385 - 385 aa - 385 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3428+/-0.00106; mu= 7.4251+/- 0.061 mean_var=231.7690+/-52.978, 0's: 0 Z-trim(110.0): 653 B-trim: 0 in 0/51 Lambda= 0.084245 statistics sampled from 10521 (11311) to 10521 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.694), E-opt: 0.2 (0.347), width: 16 Scan time: 2.870 The best scores are: opt bits E(32554) CCDS6240.1 PSKH2 gene_id:85481|Hs108|chr8 ( 385) 2546 322.8 3.3e-88 CCDS10851.1 PSKH1 gene_id:5681|Hs108|chr16 ( 424) 1583 205.8 6.1e-53 CCDS7092.1 CAMK1D gene_id:57118|Hs108|chr10 ( 357) 852 116.8 3e-26 CCDS7091.1 CAMK1D gene_id:57118|Hs108|chr10 ( 385) 852 116.9 3.2e-26 CCDS35503.2 PNCK gene_id:139728|Hs108|chrX ( 426) 836 115.0 1.3e-25 CCDS2582.1 CAMK1 gene_id:8536|Hs108|chr3 ( 370) 833 114.5 1.5e-25 CCDS48189.1 PNCK gene_id:139728|Hs108|chrX ( 360) 795 109.9 3.7e-24 CCDS1486.1 CAMK1G gene_id:57172|Hs108|chr1 ( 476) 776 107.8 2.2e-23 CCDS4103.1 CAMK4 gene_id:814|Hs108|chr5 ( 473) 762 106.0 7.1e-23 CCDS55895.1 DCLK1 gene_id:9201|Hs108|chr13 ( 433) 696 98.0 1.7e-20 CCDS81762.1 DCLK1 gene_id:9201|Hs108|chr13 ( 740) 696 98.3 2.4e-20 CCDS34076.1 DCLK2 gene_id:166614|Hs108|chr4 ( 766) 696 98.3 2.5e-20 CCDS47142.2 DCLK2 gene_id:166614|Hs108|chr4 ( 783) 696 98.3 2.5e-20 CCDS73561.1 DCLK1 gene_id:9201|Hs108|chr13 ( 422) 690 97.2 2.8e-20 CCDS82776.1 CAMKV gene_id:79012|Hs108|chr3 ( 470) 690 97.3 3e-20 CCDS33762.1 CAMKV gene_id:79012|Hs108|chr3 ( 501) 690 97.3 3.2e-20 CCDS9354.1 DCLK1 gene_id:9201|Hs108|chr13 ( 729) 690 97.5 4e-20 CCDS83147.1 RPS6KA2 gene_id:6196|Hs108|chr6 ( 644) 636 90.9 3.5e-18 CCDS43064.1 DCLK3 gene_id:85443|Hs108|chr3 ( 648) 636 90.9 3.5e-18 CCDS5294.1 RPS6KA2 gene_id:6196|Hs108|chr6 ( 733) 636 91.0 3.8e-18 CCDS34570.1 RPS6KA2 gene_id:6196|Hs108|chr6 ( 741) 636 91.0 3.8e-18 CCDS83148.1 RPS6KA2 gene_id:6196|Hs108|chr6 ( 758) 636 91.0 3.9e-18 CCDS82948.1 CAMK2D gene_id:817|Hs108|chr4 ( 512) 627 89.7 6.5e-18 CCDS82949.1 CAMK2D gene_id:817|Hs108|chr4 ( 533) 627 89.7 6.6e-18 CCDS3704.1 CAMK2D gene_id:817|Hs108|chr4 ( 478) 622 89.0 9.4e-18 CCDS43263.1 CAMK2D gene_id:817|Hs108|chr4 ( 478) 622 89.0 9.4e-18 CCDS54797.1 CAMK2D gene_id:817|Hs108|chr4 ( 489) 622 89.0 9.6e-18 CCDS47127.1 CAMK2D gene_id:817|Hs108|chr4 ( 492) 622 89.1 9.6e-18 CCDS82950.1 CAMK2D gene_id:817|Hs108|chr4 ( 498) 622 89.1 9.7e-18 CCDS3703.1 CAMK2D gene_id:817|Hs108|chr4 ( 499) 622 89.1 9.7e-18 CCDS12116.1 DAPK3 gene_id:1613|Hs108|chr19 ( 454) 620 88.8 1.1e-17 CCDS43842.1 DAPK1 gene_id:1612|Hs108|chr9 (1430) 626 90.1 1.3e-17 CCDS7336.1 CAMK2G gene_id:818|Hs108|chr10 ( 495) 618 88.6 1.4e-17 CCDS7337.1 CAMK2G gene_id:818|Hs108|chr10 ( 527) 618 88.6 1.4e-17 CCDS73153.1 CAMK2G gene_id:818|Hs108|chr10 ( 539) 618 88.6 1.4e-17 CCDS7338.1 CAMK2G gene_id:818|Hs108|chr10 ( 556) 618 88.6 1.5e-17 CCDS10188.1 DAPK2 gene_id:23604|Hs108|chr15 ( 370) 613 87.8 1.7e-17 CCDS14197.1 RPS6KA3 gene_id:6197|Hs108|chrX ( 740) 616 88.5 2e-17 CCDS34330.1 MYLK4 gene_id:340156|Hs108|chr6 ( 388) 606 87.0 3.2e-17 CCDS43386.1 CAMK2A gene_id:815|Hs108|chr5 ( 478) 607 87.2 3.3e-17 CCDS43387.1 CAMK2A gene_id:815|Hs108|chr5 ( 489) 607 87.2 3.4e-17 CCDS43141.1 MYLK gene_id:4638|Hs108|chr3 (1845) 611 88.4 5.5e-17 CCDS81286.1 RPS6KA1 gene_id:6195|Hs108|chr1 ( 719) 604 87.1 5.5e-17 CCDS284.1 RPS6KA1 gene_id:6195|Hs108|chr1 ( 735) 604 87.1 5.6e-17 CCDS46896.1 MYLK gene_id:4638|Hs108|chr3 (1914) 611 88.5 5.6e-17 CCDS30649.1 RPS6KA1 gene_id:6195|Hs108|chr1 ( 744) 604 87.1 5.7e-17 CCDS5489.1 CAMK2B gene_id:816|Hs108|chr7 ( 449) 598 86.1 6.9e-17 CCDS5488.1 CAMK2B gene_id:816|Hs108|chr7 ( 479) 598 86.1 7.1e-17 CCDS5487.1 CAMK2B gene_id:816|Hs108|chr7 ( 492) 598 86.1 7.3e-17 CCDS5486.1 CAMK2B gene_id:816|Hs108|chr7 ( 503) 598 86.1 7.4e-17 >>CCDS6240.1 PSKH2 gene_id:85481|Hs108|chr8 (385 aa) initn: 2546 init1: 2546 opt: 2546 Z-score: 1697.0 bits: 322.8 E(32554): 3.3e-88 Smith-Waterman score: 2546; 100.0% identity (100.0% similar) in 385 aa overlap (1-385:1-385) 10 20 30 40 50 60 pF1KE0 MGCGASRKVVPGPPALAWAKHEGQNQAGVGGAGPGPEAAAQAAQRIQVARFRAKFDPRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 MGCGASRKVVPGPPALAWAKHEGQNQAGVGGAGPGPEAAAQAAQRIQVARFRAKFDPRVL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ARYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACVSELSVLRRVSHRYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 ARYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACVSELSVLRRVSHRYI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 VQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQIT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 HRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 HRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 SAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 SAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 LILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAISRNLMQRASPHSQSPGSAQSSKSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 LILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAISRNLMQRASPHSQSPGSAQSSKSH 310 320 330 340 350 360 370 380 pF1KE0 YSHKSRHMWSKRNLRIVESPLSALL ::::::::::::::::::::::::: CCDS62 YSHKSRHMWSKRNLRIVESPLSALL 370 380 >>CCDS10851.1 PSKH1 gene_id:5681|Hs108|chr16 (424 aa) initn: 1610 init1: 1556 opt: 1583 Z-score: 1064.0 bits: 205.8 E(32554): 6.1e-53 Smith-Waterman score: 1583; 65.4% identity (84.6% similar) in 370 aa overlap (9-375:48-412) 10 20 30 pF1KE0 MGCGASRKVVPGPPALAWAKHEGQNQAGVGGAGPGPEA : : :: . : . .: . : : CCDS10 LDLVKKVEPFSGTKSDVYKHFITEVDSVGPVKAGFPAASQYAHPCPGPPTAGHTEP-P-- 20 30 40 50 60 70 40 50 60 70 80 90 pF1KE0 AAQAAQRIQVARFRAKFDPRVLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETRE .. .: .::..:::::::: :.:::::::: ::::::::::...:..:.:::..::. CCDS10 -SEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKY 80 90 100 110 120 130 100 110 120 130 140 150 pF1KE0 REGREACVSELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTER :::::.: ::: ::::: : :.::.:.:::...::::::::::::::::.::.:::::: CCDS10 REGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTER 140 150 160 170 180 190 160 170 180 190 200 210 pF1KE0 DAVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWT ::.:.:::: ::.:::::: ::::.:::::::::::: .:::.::::::: . ::. : CCDS10 DATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCL 200 210 220 230 240 250 220 230 240 250 260 270 pF1KE0 MKTLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGK ::: ::::::::::::.:::::..:::::::::.: :::: .::.:...:::::.::.:: CCDS10 MKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGK 260 270 280 290 300 310 280 290 300 310 320 330 pF1KE0 YNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAISR :.:.::::::.:.:::::::.:: .. : ::.: ::: ::::..:::.::::::.:.::. CCDS10 YSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHRSISQ 320 330 340 350 360 370 340 350 360 370 380 pF1KE0 NLMQRASPHSQSPGSAQS---SKSHYSHKSRHMWSKRNLRIVESPLSALL ::..::: . :: :::: :.: :.:::.. .:.:: CCDS10 NLLKRASSRCQSTKSAQSTRSSRSTRSNKSRRV-RERELRELNLRYQQQYNG 380 390 400 410 420 >>CCDS7092.1 CAMK1D gene_id:57118|Hs108|chr10 (357 aa) initn: 828 init1: 378 opt: 852 Z-score: 584.7 bits: 116.8 E(32554): 3e-26 Smith-Waterman score: 852; 46.2% identity (78.1% similar) in 279 aa overlap (63-337:23-294) 40 50 60 70 80 90 pF1KE0 GPGPEAAAQAAQRIQVARFRAKFDPRVLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIK ...: .:::.::.:: .:.:.: : ::.: CCDS70 MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVK 10 20 30 40 50 100 110 120 130 140 150 pF1KE0 VMETREREGREACV-SELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIA . . .:.:. . .:..:::...:. :: : .:.:. ...:.::.:..:::::::.. CCDS70 CIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVE 60 70 80 90 100 110 160 170 180 190 200 210 pF1KE0 QGSFTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLA-YS .: .::.:: ....: :.. ::: . :.::.::::::::: :::::.:.::::. . CCDS70 KGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKME 120 130 140 150 160 170 220 230 240 250 260 270 pF1KE0 GKKSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYALLSGFLPFDDESQTRL :: :: .:.: :::: :.::::: .:::..::: :..:::.: :: :. :: ::....: CCDS70 GK--GD-VMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKL 180 190 200 210 220 280 290 300 310 320 pF1KE0 YRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWVITMAAGSSM- ...:::..:.. . : .:: ::::: .:. . ..:.. :: :::. ::.. CCDS70 FEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI----AGDTAL 230 240 250 260 270 280 330 340 350 360 370 380 pF1KE0 -KNLQRAISRNLMQRASPHSQSPGSAQSSKSHYSHKSRHMWSKRNLRIVESPLSALL ::.....: CCDS70 NKNIHESVSAQIRKNFAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQK 290 300 310 320 330 340 >>CCDS7091.1 CAMK1D gene_id:57118|Hs108|chr10 (385 aa) initn: 828 init1: 378 opt: 852 Z-score: 584.3 bits: 116.9 E(32554): 3.2e-26 Smith-Waterman score: 852; 46.2% identity (78.1% similar) in 279 aa overlap (63-337:23-294) 40 50 60 70 80 90 pF1KE0 GPGPEAAAQAAQRIQVARFRAKFDPRVLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIK ...: .:::.::.:: .:.:.: : ::.: CCDS70 MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVK 10 20 30 40 50 100 110 120 130 140 150 pF1KE0 VMETREREGREACV-SELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIA . . .:.:. . .:..:::...:. :: : .:.:. ...:.::.:..:::::::.. CCDS70 CIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVE 60 70 80 90 100 110 160 170 180 190 200 210 pF1KE0 QGSFTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLA-YS .: .::.:: ....: :.. ::: . :.::.::::::::: :::::.:.::::. . CCDS70 KGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKME 120 130 140 150 160 170 220 230 240 250 260 270 pF1KE0 GKKSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYALLSGFLPFDDESQTRL :: :: .:.: :::: :.::::: .:::..::: :..:::.: :: :. :: ::....: CCDS70 GK--GD-VMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKL 180 190 200 210 220 280 290 300 310 320 pF1KE0 YRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWVITMAAGSSM- ...:::..:.. . : .:: ::::: .:. . ..:.. :: :::. ::.. CCDS70 FEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI----AGDTAL 230 240 250 260 270 280 330 340 350 360 370 380 pF1KE0 -KNLQRAISRNLMQRASPHSQSPGSAQSSKSHYSHKSRHMWSKRNLRIVESPLSALL ::.....: CCDS70 NKNIHESVSAQIRKNFAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQK 290 300 310 320 330 340 >>CCDS35503.2 PNCK gene_id:139728|Hs108|chrX (426 aa) initn: 717 init1: 368 opt: 836 Z-score: 573.3 bits: 115.0 E(32554): 1.3e-25 Smith-Waterman score: 836; 40.2% identity (68.9% similar) in 351 aa overlap (4-344:38-383) 10 20 30 pF1KE0 MGCGASRKVVPGP---PALAWAKHEGQNQAGVG : :.. :: :: .. .. ..:.: CCDS35 VAGSACPRRGGEGRDWKAESLADLWPKSSPGDSHRWCKGPGAGPAGPQLREAARASSGLG 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 GAGPGPEAAAQAAQRIQVARFRAKFDPRVLARYDIKALIGTGSFSRVVRVEQKTTKKPFA :.: : : .: . : . . :.:. .:.:.::.:: .... . . : CCDS35 GGGRHPSRIPAIA--LQDMLLLKKHTEDISSVYEIRERLGSGAFSEVVLAQERGSAHLVA 70 80 90 100 110 120 100 110 120 130 140 pF1KE0 IKVMETREREGREACV-SELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRL .: . . .:.:: : .:..::::.:: :: : .. :. ...:..:::.::::::::. CCDS35 LKCIPKKALRGKEALVENEIAVLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRI 130 140 150 160 170 180 150 160 170 180 190 200 pF1KE0 IAQGSFTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLAY . .::.::.:: ... .: .. :::.: :.::.:::::::: : :.:::...:::: CCDS35 MERGSYTEKDASHLVGQVLGAVSYLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGL-- 190 200 210 220 230 240 210 220 230 240 250 260 pF1KE0 SGKKSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYALLSGFLPFDDESQTR : ..:. . : :::: :.:::.: .::: .:::.::::::.: :: :. :: :::. . CCDS35 SKIQAGNM-LGTACGTPGYVAPELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPE 250 260 270 280 290 300 270 280 290 300 310 320 pF1KE0 LYRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWVITMAA---- :. .::...:.. . : .::. ::::: .:: . .:.. ::: : :. .: CCDS35 LFSQILRASYEFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQALRHLWISGDTAFDRD 310 320 330 340 350 360 330 340 350 360 370 380 pF1KE0 --GSSMKNLQRAISRNLMQRASPHSQSPGSAQSSKSHYSHKSRHMWSKRNLRIVESPLSA :: ..... ..:. .:: CCDS35 ILGSVSEQIRKNFARTHWKRAFNATSFLRHIRKLGQIPEGEGASEQGMARHSHSGLRAGQ 370 380 390 400 410 420 >>CCDS2582.1 CAMK1 gene_id:8536|Hs108|chr3 (370 aa) initn: 830 init1: 366 opt: 833 Z-score: 572.0 bits: 114.5 E(32554): 1.5e-25 Smith-Waterman score: 833; 43.6% identity (75.8% similar) in 298 aa overlap (46-340:5-294) 20 30 40 50 60 70 pF1KE0 LAWAKHEGQNQAGVGGAGPGPEAAAQAAQRIQVARFRAKFDPRVLARYDIKALIGTGSFS .. :.. : : . ::.. ..:::.:: CCDS25 MLGAVEGPRWKQAEDIRDI--YDFRDVLGTGAFS 10 20 30 80 90 100 110 120 130 pF1KE0 RVVRVEQKTTKKPFAIKVMETREREGREACV-SELSVLRRVSHRYIVQLMEIFETEDQVY .:. .:.: :.: ::: . . ::.:. . .:..::....: :: : .:.:. ..: CCDS25 EVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKIKHPNIVALDDIYESGGHLY 40 50 60 70 80 90 140 150 160 170 180 190 pF1KE0 MVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHP ..:.:..:::::::.. .: .::::: :.. .: :...::: : :.::.::::::::: CCDS25 LIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSL 100 110 120 130 140 150 200 210 220 230 240 250 pF1KE0 GEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYA :.:::.:.:::: : .. ...: :::: :.::::: .:::..::: :..:::.: CCDS25 DEDSKIMISDFGL--SKMEDPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYI 160 170 180 190 200 210 260 270 280 290 300 310 pF1KE0 LLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQA :: :. :: ::....:...:::..:.. . : .:: ::::: .:. . .:.. :: CCDS25 LLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQA 220 230 240 250 260 270 320 330 340 350 360 370 pF1KE0 LDHPWVITMAAGSSM--KNLQRAISRNLMQRASPHSQSPGSAQSSKSHYSHKSRHMWSKR :.:::. ::.. ::.....:... CCDS25 LQHPWI----AGDTALDKNIHQSVSEQIKKNFAKSKWKQAFNATAVVRHMRKLQLGTSQE 280 290 300 310 320 >>CCDS48189.1 PNCK gene_id:139728|Hs108|chrX (360 aa) initn: 718 init1: 368 opt: 795 Z-score: 547.2 bits: 109.9 E(32554): 3.7e-24 Smith-Waterman score: 795; 43.9% identity (74.0% similar) in 289 aa overlap (63-344:32-317) 40 50 60 70 80 90 pF1KE0 GPGPEAAAQAAQRIQVARFRAKFDPRVLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIK :.:. .:.:.::.:: .... . . :.: CCDS48 WRRVCGGLAGRRPSGDMLLLKKHTEDISSVYEIRERLGSGAFSEVVLAQERGSAHLVALK 10 20 30 40 50 60 100 110 120 130 140 150 pF1KE0 VMETREREGREACV-SELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIA . . .:.:: : .:..::::.:: :: : .. :. ...:..:::.::::::::.. CCDS48 CIPKKALRGKEALVENEIAVLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRIME 70 80 90 100 110 120 160 170 180 190 200 210 pF1KE0 QGSFTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLAYSG .::.::.:: ... .: .. :::.: :.::.:::::::: : :.:::...:::: : CCDS48 RGSYTEKDASHLVGQVLGAVSYLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGL--SK 130 140 150 160 170 220 230 240 250 260 270 pF1KE0 KKSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYALLSGFLPFDDESQTRLY ..:. . : :::: :.:::.: .::: .:::.::::::.: :: :. :: :::. .:. CCDS48 IQAGNM-LGTACGTPGYVAPELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPELF 180 190 200 210 220 230 280 290 300 310 320 pF1KE0 RKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWVITMAA------ .::...:.. . : .::. ::::: .:: . .:.. ::: : :. .: CCDS48 SQILRASYEFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQALRHLWISGDTAFDRDIL 240 250 260 270 280 290 330 340 350 360 370 380 pF1KE0 GSSMKNLQRAISRNLMQRASPHSQSPGSAQSSKSHYSHKSRHMWSKRNLRIVESPLSALL :: ..... ..:. .:: CCDS48 GSVSEQIRKNFARTHWKRAFNATSFLRHIRKLGQIPEGEGASEQGMARHSHSGLRAGQPP 300 310 320 330 340 350 >>CCDS1486.1 CAMK1G gene_id:57172|Hs108|chr1 (476 aa) initn: 770 init1: 408 opt: 776 Z-score: 533.4 bits: 107.8 E(32554): 2.2e-23 Smith-Waterman score: 776; 45.8% identity (75.5% similar) in 253 aa overlap (68-320:28-277) 40 50 60 70 80 90 pF1KE0 AAAQAAQRIQVARFRAKFDPRVLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETR ..:.:.::.: :.:. : : ::.: .. CCDS14 MGRKEEDDCSSWKKQTTNIRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKS 10 20 30 40 50 100 110 120 130 140 150 pF1KE0 EREGREACVSELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTE . .:..::....:. :: : .:.:. . :.::.:..:::::::.. .: .:: CCDS14 PAFRDSSLENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTE 60 70 80 90 100 110 160 170 180 190 200 210 pF1KE0 RDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDW .:: ..:.: ....::: :.::.:::::::: : :.:::.::::::. : . CCDS14 KDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLS---KMEQNG 120 130 140 150 160 170 220 230 240 250 260 270 pF1KE0 TMKTLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKG :.: :::: :.::::: .:::..::: :..::::: :: :. :: .:....:..:: .: CCDS14 IMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEG 180 190 200 210 220 230 280 290 300 310 320 330 pF1KE0 KYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAIS :.. . : .::. ::::: .:: . ..:.. .::.:::. CCDS14 YYEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWIDGNTALHRDIYPSVSLQ 240 250 260 270 280 290 340 350 360 370 380 pF1KE0 RNLMQRASPHSQSPGSAQSSKSHYSHKSRHMWSKRNLRIVESPLSALL CCDS14 IQKNFAKSKWRQAFNAAAVVHHMRKLHMNLHSPGVRPEVENRPPETQASETSRPSSPEIT 300 310 320 330 340 350 >>CCDS4103.1 CAMK4 gene_id:814|Hs108|chr5 (473 aa) initn: 622 init1: 342 opt: 762 Z-score: 524.2 bits: 106.0 E(32554): 7.1e-23 Smith-Waterman score: 762; 40.8% identity (68.8% similar) in 314 aa overlap (63-365:46-355) 40 50 60 70 80 90 pF1KE0 GPGPEAAAQAAQRIQVARFRAKFDPRVLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIK ..... .: :. : : : .:: :.::.:.: CCDS41 SVTASAAPGTASLVPDYWIDGSNRDALSDFFEVESELGRGATSIVYRCKQKGTQKPYALK 20 30 40 50 60 70 100 110 120 130 140 150 pF1KE0 VMETREREGREACVSELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQ :. .. .. .:..:: :.:: :..: ::::: .. .:.::.::::::::.. . CCDS41 VL--KKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEK 80 90 100 110 120 130 160 170 180 190 200 210 pF1KE0 GSFTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLAYSGK : ..::::. .... ... ::: :.::.:::::::: :. .. . :.:::: : CCDS41 GYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGL--SKI 140 150 160 170 180 190 220 230 240 250 260 270 pF1KE0 KSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYALLSGFLPFDDESQTR-LY . :::.:::: : :::.: : ::::..:.::: :: :: :: :: . .. CCDS41 VEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQFMF 200 210 220 230 240 250 280 290 300 310 320 pF1KE0 RKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWVITMAAG----- :.::. .: . . : .: :::.. ::..:. .:... :::.:::: ::. CCDS41 RRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWVTGKAANFVHMD 260 270 280 290 300 310 330 340 350 360 370 380 pF1KE0 SSMKNLQRAISRNLMQ---RASPHSQSPGSAQSSKS--HYSHKSRHMWSKRNLRIVESPL ...:.::. .: .. .: :. :::.::.. . :::. CCDS41 TAQKKLQEFNARRKLKAAVKAVVASSRLGSASSSHGSIQESHKASRDPSPIQDGNEDMKA 320 330 340 350 360 370 pF1KE0 SALL CCDS41 IPEGEKIQGDGAQAAVKGAQAELMKVQALEKVKGADINAEEAPKMVPKAVEDGIKVADLE 380 390 400 410 420 430 >>CCDS55895.1 DCLK1 gene_id:9201|Hs108|chr13 (433 aa) initn: 598 init1: 294 opt: 696 Z-score: 481.3 bits: 98.0 E(32554): 1.7e-20 Smith-Waterman score: 700; 35.3% identity (65.0% similar) in 357 aa overlap (33-383:63-404) 10 20 30 40 50 60 pF1KE0 CGASRKVVPGPPALAWAKHEGQNQAGVGGAGPGPEAAAQAAQRIQVARFRAKFDPRVLAR ::: :.. .. : . . : CCDS55 SLRKQRSSQHGGSSTSLASTKVCSSMDENDGPGEEVSEEGFQ----------IPATITER 40 50 60 70 80 70 80 90 100 110 120 pF1KE0 YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACV-SELSVLRRVSHRYIV : . :: :.:. : . ...: . .:.:... . .:.: . .:.:.::::.: :: CCDS55 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIV 90 100 110 120 130 140 130 140 150 160 170 180 pF1KE0 QLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQITH :.: ... ..:.::::. ::.::: . . ...::::: .: .:..:.:::.:.:.: CCDS55 LLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVH 150 160 170 180 190 200 190 200 210 220 230 240 pF1KE0 RNLKPENLLYYHPGEESKIL-ITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYT :..:::::: :. . :: : . ::::: : . :.:::: :.:::.. . : CCDS55 RDIKPENLLVYEHQDGSKSLKLGDFGLA----TIVDGPLYTVCGTPTYVAPEIIAETGYG 210 220 230 240 250 250 260 270 280 290 pF1KE0 SAVDMWALGVITYALLSGFLPF--DDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFID ::.:: ::::: :: :: :: . ..: :. .:: :. .. . : ..: ::..: CCDS55 LKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELIT 260 270 280 290 300 310 300 310 320 330 340 350 pF1KE0 KLLILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRA--ISRNLMQRASPHSQSPGSAQS .:.... .:.:: :.:.:::: . . ..:. : :.... .:.: . : . CCDS55 MMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLSVAGKIKKHFNTGPKPNSTAAGVSVI 320 330 340 350 360 370 360 370 380 pF1KE0 SKSHYSHKSRHMWSKRNLRIVESPLSALL . . . : :... .: . :.: .: CCDS55 ATTALD-KERQVFRRRRNQDVRSRYKAQPAPPELNSESEDYSPSSSETVRSPNSPF 380 390 400 410 420 430 385 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 18 17:34:51 2016 done: Fri Nov 18 17:34:52 2016 Total Scan time: 2.870 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]