FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0951, 473 aa 1>>>pF1KE0951 473 - 473 aa - 473 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.0216+/-0.00123; mu= 4.3799+/- 0.070 mean_var=225.9722+/-51.873, 0's: 0 Z-trim(108.2): 667 B-trim: 133 in 1/49 Lambda= 0.085319 statistics sampled from 9277 (10030) to 9277 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.308), width: 16 Scan time: 2.870 The best scores are: opt bits E(32554) CCDS4103.1 CAMK4 gene_id:814|Hs108|chr5 ( 473) 3092 394.3 1.5e-109 CCDS48189.1 PNCK gene_id:139728|Hs108|chrX ( 360) 935 128.6 1e-29 CCDS35503.2 PNCK gene_id:139728|Hs108|chrX ( 426) 935 128.7 1.2e-29 CCDS2582.1 CAMK1 gene_id:8536|Hs108|chr3 ( 370) 927 127.7 2.1e-29 CCDS7092.1 CAMK1D gene_id:57118|Hs108|chr10 ( 357) 921 126.9 3.4e-29 CCDS7091.1 CAMK1D gene_id:57118|Hs108|chr10 ( 385) 921 127.0 3.6e-29 CCDS1486.1 CAMK1G gene_id:57172|Hs108|chr1 ( 476) 886 122.7 8.2e-28 CCDS54797.1 CAMK2D gene_id:817|Hs108|chr4 ( 489) 852 118.6 1.5e-26 CCDS47127.1 CAMK2D gene_id:817|Hs108|chr4 ( 492) 851 118.4 1.7e-26 CCDS43263.1 CAMK2D gene_id:817|Hs108|chr4 ( 478) 847 117.9 2.3e-26 CCDS3704.1 CAMK2D gene_id:817|Hs108|chr4 ( 478) 847 117.9 2.3e-26 CCDS3703.1 CAMK2D gene_id:817|Hs108|chr4 ( 499) 847 118.0 2.4e-26 CCDS82950.1 CAMK2D gene_id:817|Hs108|chr4 ( 498) 843 117.5 3.3e-26 CCDS7336.1 CAMK2G gene_id:818|Hs108|chr10 ( 495) 836 116.6 6e-26 CCDS82948.1 CAMK2D gene_id:817|Hs108|chr4 ( 512) 835 116.5 6.7e-26 CCDS82949.1 CAMK2D gene_id:817|Hs108|chr4 ( 533) 835 116.5 6.9e-26 CCDS43387.1 CAMK2A gene_id:815|Hs108|chr5 ( 489) 827 115.5 1.3e-25 CCDS43386.1 CAMK2A gene_id:815|Hs108|chr5 ( 478) 822 114.9 1.9e-25 CCDS73153.1 CAMK2G gene_id:818|Hs108|chr10 ( 539) 817 114.3 3.2e-25 CCDS5488.1 CAMK2B gene_id:816|Hs108|chr7 ( 479) 812 113.6 4.6e-25 CCDS7338.1 CAMK2G gene_id:818|Hs108|chr10 ( 556) 813 113.8 4.6e-25 CCDS7337.1 CAMK2G gene_id:818|Hs108|chr10 ( 527) 810 113.4 5.8e-25 CCDS10851.1 PSKH1 gene_id:5681|Hs108|chr16 ( 424) 801 112.2 1.1e-24 CCDS43573.1 CAMK2B gene_id:816|Hs108|chr7 ( 517) 802 112.4 1.1e-24 CCDS5486.1 CAMK2B gene_id:816|Hs108|chr7 ( 503) 800 112.2 1.3e-24 CCDS5485.1 CAMK2B gene_id:816|Hs108|chr7 ( 518) 800 112.2 1.3e-24 CCDS55895.1 DCLK1 gene_id:9201|Hs108|chr13 ( 433) 797 111.7 1.5e-24 CCDS43064.1 DCLK3 gene_id:85443|Hs108|chr3 ( 648) 799 112.2 1.7e-24 CCDS5489.1 CAMK2B gene_id:816|Hs108|chr7 ( 449) 794 111.4 2e-24 CCDS81762.1 DCLK1 gene_id:9201|Hs108|chr13 ( 740) 797 112.0 2.2e-24 CCDS5487.1 CAMK2B gene_id:816|Hs108|chr7 ( 492) 792 111.2 2.6e-24 CCDS73561.1 DCLK1 gene_id:9201|Hs108|chr13 ( 422) 790 110.9 2.7e-24 CCDS5484.1 CAMK2B gene_id:816|Hs108|chr7 ( 542) 792 111.2 2.7e-24 CCDS5483.1 CAMK2B gene_id:816|Hs108|chr7 ( 666) 792 111.3 3.2e-24 CCDS9354.1 DCLK1 gene_id:9201|Hs108|chr13 ( 729) 790 111.1 4e-24 CCDS33762.1 CAMKV gene_id:79012|Hs108|chr3 ( 501) 766 108.0 2.4e-23 CCDS6240.1 PSKH2 gene_id:85481|Hs108|chr8 ( 385) 762 107.4 2.8e-23 CCDS82776.1 CAMKV gene_id:79012|Hs108|chr3 ( 470) 759 107.1 4.1e-23 CCDS34076.1 DCLK2 gene_id:166614|Hs108|chr4 ( 766) 761 107.6 4.9e-23 CCDS47142.2 DCLK2 gene_id:166614|Hs108|chr4 ( 783) 761 107.6 5e-23 CCDS43842.1 DAPK1 gene_id:1612|Hs108|chr9 (1430) 733 104.4 8.2e-22 CCDS12116.1 DAPK3 gene_id:1613|Hs108|chr19 ( 454) 718 102.0 1.3e-21 CCDS83147.1 RPS6KA2 gene_id:6196|Hs108|chr6 ( 644) 683 97.9 3.4e-20 CCDS5294.1 RPS6KA2 gene_id:6196|Hs108|chr6 ( 733) 683 98.0 3.7e-20 CCDS34570.1 RPS6KA2 gene_id:6196|Hs108|chr6 ( 741) 683 98.0 3.7e-20 CCDS83148.1 RPS6KA2 gene_id:6196|Hs108|chr6 ( 758) 683 98.0 3.8e-20 CCDS10188.1 DAPK2 gene_id:23604|Hs108|chr15 ( 370) 676 96.8 4.2e-20 CCDS43141.1 MYLK gene_id:4638|Hs108|chr3 (1845) 686 98.7 5.4e-20 CCDS46896.1 MYLK gene_id:4638|Hs108|chr3 (1914) 686 98.8 5.5e-20 CCDS13843.1 CHEK2 gene_id:11200|Hs108|chr22 ( 543) 665 95.6 1.4e-19 >>CCDS4103.1 CAMK4 gene_id:814|Hs108|chr5 (473 aa) initn: 3092 init1: 3092 opt: 3092 Z-score: 2080.3 bits: 394.3 E(32554): 1.5e-109 Smith-Waterman score: 3092; 100.0% identity (100.0% similar) in 473 aa overlap (1-473:1-473) 10 20 30 40 50 60 pF1KE0 MLKVTVPSCSASSCSSVTASAAPGTASLVPDYWIDGSNRDALSDFFEVESELGRGATSIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 MLKVTVPSCSASSCSSVTASAAPGTASLVPDYWIDGSNRDALSDFFEVESELGRGATSIV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 YRCKQKGTQKPYALKVLKKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 YRCKQKGTQKPYALKVLKKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLEL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 VTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 FYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 FYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 TGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSRLGSASSSHGSIQESHKASRDPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 TGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSRLGSASSSHGSIQESHKASRDPS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 PIQDGNEDMKAIPEGEKIQGDGAQAAVKGAQAELMKVQALEKVKGADINAEEAPKMVPKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 PIQDGNEDMKAIPEGEKIQGDGAQAAVKGAQAELMKVQALEKVKGADINAEEAPKMVPKA 370 380 390 400 410 420 430 440 450 460 470 pF1KE0 VEDGIKVADLELEEGLAEEKLKTVEEAAAPREGQGSSAVGFEVPQQDVILPEY ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 VEDGIKVADLELEEGLAEEKLKTVEEAAAPREGQGSSAVGFEVPQQDVILPEY 430 440 450 460 470 >>CCDS48189.1 PNCK gene_id:139728|Hs108|chrX (360 aa) initn: 885 init1: 449 opt: 935 Z-score: 646.8 bits: 128.6 E(32554): 1e-29 Smith-Waterman score: 935; 43.8% identity (71.6% similar) in 352 aa overlap (24-361:8-357) 10 20 30 40 50 pF1KE0 MLKVTVPSCSASSCSSVTASAAPGTASLVP--DYWIDGSNRDALSDFFEVESELGRGATS : :. : :. . .. . .:. .:.. .:: :: : CCDS48 MWRRVCGGLAGRRPSGDMLLLKKHTEDISSVYEIRERLGSGAFS 10 20 30 40 60 70 80 90 100 110 pF1KE0 IVYRCKQKGTQKPYALKVL-KKTVDKK--IVRTEIGVLLRLSHPNIIKLKEIFETPTEIS : ...:. . ::: . ::.. : .:..::.:: :.:::::. :... :.:... CCDS48 EVVLAQERGSAHLVALKCIPKKALRGKEALVENEIAVLRRISHPNIVALEDVHESPSHLY 50 60 70 80 90 100 120 130 140 150 160 170 pF1KE0 LVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATP :..::::::::::::.:.: :.:.::. : :.: ::.::: ::::::::::::::::: CCDS48 LAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIVHRDLKPENLLYATP 110 120 130 140 150 160 180 190 200 210 220 230 pF1KE0 APDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILL :. . ..::::::: . .. :.:::::: :::.:. :: ::.:..:.:.:::: CCDS48 FEDSKIMVSDFGLSKI-QAGNMLGTACGTPGYVAPELLEQKPYGKAVDVWALGVISYILL 170 180 190 200 210 220 240 250 260 270 280 290 pF1KE0 CGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQAL ::. ::::: .: .: .:: : : ::.::..: .:::..:.:. ::.::.: ::: CCDS48 CGYPPFYDE-SDPELFSQILRASYEFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQAL 230 240 250 260 270 280 300 310 320 330 340 pF1KE0 QHPWVTGKAA-NFVHMDTAQKKLQEFNARRKLKAAVKAVVASSRL--------GSASSSH .: :..: .: . . ........ :: . : : .:. .. : ..: . CCDS48 RHLWISGDTAFDRDILGSVSEQIRKNFARTHWKRAFNATSFLRHIRKLGQIPEGEGASEQ 290 300 310 320 330 340 350 360 370 380 390 400 pF1KE0 GSIQESHKASRDPSPIQDGNEDMKAIPEGEKIQGDGAQAAVKGAQAELMKVQALEKVKGA : ..::.. : .: CCDS48 GMARHSHSGLRAGQPPKW 350 360 >>CCDS35503.2 PNCK gene_id:139728|Hs108|chrX (426 aa) initn: 885 init1: 449 opt: 935 Z-score: 645.9 bits: 128.7 E(32554): 1.2e-29 Smith-Waterman score: 935; 43.5% identity (71.5% similar) in 354 aa overlap (20-361:74-423) 10 20 30 40 pF1KE0 MLKVTVPSCSASSCSSVTASAAPGTASLVPDYWIDGSNRDALSDFFEVE : :. : . :. . .. . .:. .:.. CCDS35 CKGPGAGPAGPQLREAARASSGLGGGGRHPSRIPAIA--LQDMLLLKKHTEDISSVYEIR 50 60 70 80 90 100 50 60 70 80 90 100 pF1KE0 SELGRGATSIVYRCKQKGTQKPYALKVL-KKTVDKK--IVRTEIGVLLRLSHPNIIKLKE .:: :: : : ...:. . ::: . ::.. : .:..::.:: :.:::::. :.. CCDS35 ERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKEALVENEIAVLRRISHPNIVALED 110 120 130 140 150 160 110 120 130 140 150 160 pF1KE0 IFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLK . :.:... :..::::::::::::.:.: :.:.::. : :.: ::.::: :::::::: CCDS35 VHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIVHRDLK 170 180 190 200 210 220 170 180 190 200 210 220 pF1KE0 PENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWS ::::::::: :. . ..::::::: . .. :.:::::: :::.:. :: ::.:. CCDS35 PENLLYATPFEDSKIMVSDFGLSKI-QAGNMLGTACGTPGYVAPELLEQKPYGKAVDVWA 230 240 250 260 270 280 230 240 250 260 270 280 pF1KE0 VGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPK .:.:.::::::. ::::: .: .: .:: : : ::.::..: .:::..:.:. ::. CCDS35 LGVISYILLCGYPPFYDE-SDPELFSQILRASYEFDSPFWDDISESAKDFIRHLLERDPQ 290 300 310 320 330 290 300 310 320 330 pF1KE0 KRLTTFQALQHPWVTGKAA-NFVHMDTAQKKLQEFNARRKLKAAVKAVVASSRL------ ::.: :::.: :..: .: . . ........ :: . : : .:. .. CCDS35 KRFTCQQALRHLWISGDTAFDRDILGSVSEQIRKNFARTHWKRAFNATSFLRHIRKLGQI 340 350 360 370 380 390 340 350 360 370 380 390 pF1KE0 --GSASSSHGSIQESHKASRDPSPIQDGNEDMKAIPEGEKIQGDGAQAAVKGAQAELMKV : ..: .: ..::.. : .: CCDS35 PEGEGASEQGMARHSHSGLRAGQPPKW 400 410 420 >>CCDS2582.1 CAMK1 gene_id:8536|Hs108|chr3 (370 aa) initn: 923 init1: 633 opt: 927 Z-score: 641.4 bits: 127.7 E(32554): 2.1e-29 Smith-Waterman score: 927; 46.6% identity (74.5% similar) in 322 aa overlap (42-353:16-334) 20 30 40 50 60 70 pF1KE0 SSCSSVTASAAPGTASLVPDYWIDGSNRDALSDFFEVESELGRGATSIVYRCKQKGTQKP . :... .. :: :: : : ..: ::: CCDS25 MLGAVEGPRWKQAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKL 10 20 30 40 80 90 100 110 120 pF1KE0 YALK-VLKKTVDKK--IVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFD :.: . :.... : ...::.:: ...::::. : .:.:. .. :...::.:::::: CCDS25 VAIKCIAKEALEGKEGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFD 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 RIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGL ::::::.:.::::. . :.:.:: :::. :::::::::::::: . :. . :.:::: CCDS25 RIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGL 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE0 SKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQ ::. . ...:.:::::: :::.: :. :: ::.:.:.::::::. ::::: .: CCDS25 SKMEDPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDE-NDA 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE0 FMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWVTGKAA--N .:..::. :: : ::.::..: .:::..:.:. ::.::.: :::::::..: .: . CCDS25 KLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIAGDTALDK 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE0 FVHMDTAQKKLQEFNARRKLKAAVKA--VVASSR---LGSASSSHGSIQESHKASRDPSP .:...... ..: :. : : : .: :: : ::... ..:. :: CCDS25 NIHQSVSEQIKKNF-AKSKWKQAFNATAVVRHMRKLQLGTSQEGQGQTA-SHGELLTPVA 290 300 310 320 330 340 370 380 390 400 410 420 pF1KE0 IQDGNEDMKAIPEGEKIQGDGAQAAVKGAQAELMKVQALEKVKGADINAEEAPKMVPKAV CCDS25 GGPAAGCCCRDCCVEPGTELSPTLPHQL 350 360 370 >>CCDS7092.1 CAMK1D gene_id:57118|Hs108|chr10 (357 aa) initn: 853 init1: 642 opt: 921 Z-score: 637.6 bits: 126.9 E(32554): 3.4e-29 Smith-Waterman score: 921; 46.3% identity (74.5% similar) in 322 aa overlap (42-352:19-338) 20 30 40 50 60 70 pF1KE0 SSCSSVTASAAPGTASLVPDYWIDGSNRDALSDFFEVESELGRGATSIVYRCKQKGTQKP .. .:: . :: :: : : ..:.: : CCDS70 MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKL 10 20 30 40 80 90 100 110 120 pF1KE0 YALKVLKKTVDK---KIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFD .:.: . : . : . ...::.:: ...: ::. :..:.:.:... ::..::.:::::: CCDS70 FAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFD 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 RIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGL ::::::.:.:.::. ..:.:.:: :::. :::::::::::::: . .. . :.:::: CCDS70 RIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGL 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE0 SKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQ ::. . .:.:.:::::: :::.: :. :: ::.:.:.::::::. ::::: .:. CCDS70 SKMEGKGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDE-NDS 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE0 FMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWVTGKAA--N .:..::. :: : ::.::..: .:::..:.:. ::.:: : :: .:::..: .: . CCDS70 KLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNK 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE0 FVHMDTAQKKLQEFNARRKLKAAVKA--VVASSR---LGSA-SSSHGSIQESHKASRDPS .: ... . ..: :. : . : .: :: : :::. .::..:.. : CCDS70 NIHESVSAQIRKNF-AKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQKD 290 300 310 320 330 340 370 380 390 400 410 420 pF1KE0 PIQDGNEDMKAIPEGEKIQGDGAQAAVKGAQAELMKVQALEKVKGADINAEEAPKMVPKA CCDS70 CAYVAKPESLS 350 >>CCDS7091.1 CAMK1D gene_id:57118|Hs108|chr10 (385 aa) initn: 849 init1: 638 opt: 921 Z-score: 637.2 bits: 127.0 E(32554): 3.6e-29 Smith-Waterman score: 921; 46.3% identity (74.5% similar) in 322 aa overlap (42-352:19-338) 20 30 40 50 60 70 pF1KE0 SSCSSVTASAAPGTASLVPDYWIDGSNRDALSDFFEVESELGRGATSIVYRCKQKGTQKP .. .:: . :: :: : : ..:.: : CCDS70 MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKL 10 20 30 40 80 90 100 110 120 pF1KE0 YALKVLKKTVDK---KIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFD .:.: . : . : . ...::.:: ...: ::. :..:.:.:... ::..::.:::::: CCDS70 FAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFD 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 RIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGL ::::::.:.:.::. ..:.:.:: :::. :::::::::::::: . .. . :.:::: CCDS70 RIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGL 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE0 SKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQ ::. . .:.:.:::::: :::.: :. :: ::.:.:.::::::. ::::: .:. CCDS70 SKMEGKGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDE-NDS 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE0 FMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWVTGKAA--N .:..::. :: : ::.::..: .:::..:.:. ::.:: : :: .:::..: .: . CCDS70 KLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNK 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE0 FVHMDTAQKKLQEFNARRKLKAAVKA--VVASSR---LGSA-SSSHGSIQESHKASRDPS .: ... . ..: :. : . : .: :: : :::. .::..:.. : CCDS70 NIHESVSAQIRKNF-AKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQKD 290 300 310 320 330 340 370 380 390 400 410 420 pF1KE0 PIQDGNEDMKAIPEGEKIQGDGAQAAVKGAQAELMKVQALEKVKGADINAEEAPKMVPKA CCDS70 CLAPSTLCSFISSSSGVSGVGAERRPRPTTVTAVHSGSK 350 360 370 380 >>CCDS1486.1 CAMK1G gene_id:57172|Hs108|chr1 (476 aa) initn: 666 init1: 427 opt: 886 Z-score: 612.8 bits: 122.7 E(32554): 8.2e-28 Smith-Waterman score: 886; 43.6% identity (71.0% similar) in 335 aa overlap (45-374:25-352) 20 30 40 50 60 70 pF1KE0 SSVTASAAPGTASLVPDYWIDGSNRDALSDFFEVESELGRGATSIVYRCKQKGTQKPYAL :.:: :: :: : :. ::. : : .:: CCDS14 MGRKEEDDCSSWKKQTTNIRKTFIFMEV---LGSGAFSEVFLVKQRLTGKLFAL 10 20 30 40 50 80 90 100 110 120 130 pF1KE0 KVLKKT--VDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVE : .::. . ...::.:: ...: ::. :..:.:. :. ::..::.::::::::.: CCDS14 KCIKKSPAFRDSSLENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILE 60 70 80 90 100 110 140 150 160 170 180 190 pF1KE0 KGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIV .: :.:.::. ...:.: :: ::::::::::::::::::: :: .. . :.::::::. CCDS14 RGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKM- 120 130 140 150 160 170 200 210 220 230 240 250 pF1KE0 EHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQFMFR :.. .:.:.:::::: :::.: :. :: ::.:.::::::::. :::.: .. .:. CCDS14 EQNGIMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETESK-LFE 180 190 200 210 220 260 270 280 290 300 310 pF1KE0 RILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWVTGKAANFVHMD- .: . : : ::.::..: .:::.. .:. ::..: : .::.:::. :..: .: : CCDS14 KIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWIDGNTA--LHRDI 230 240 250 260 270 280 320 330 340 350 360 pF1KE0 --TAQKKLQEFNARRKLKAAVKAVVASSRLGSASSSHGSIQESHKASRDPSPIQDGNEDM ... ..:. :. : . : .:... .. . . : .. : : .. . CCDS14 YPSVSLQIQKNFAKSKWRQAFNAAAVVHHMRKLHMNLHSPGVRPEVENRPPETQASETSR 290 300 310 320 330 340 370 380 390 400 410 420 pF1KE0 KAIPEGEKIQGDGAQAAVKGAQAELMKVQALEKVKGADINAEEAPKMVPKAVEDGIKVAD . :: CCDS14 PSSPEITITEAPVLDHSVALPALTQLPCQHGRRPTAPGGRSLNCLVNGSLHISSSLVPMH 350 360 370 380 390 400 >>CCDS54797.1 CAMK2D gene_id:817|Hs108|chr4 (489 aa) initn: 748 init1: 422 opt: 852 Z-score: 590.0 bits: 118.6 E(32554): 1.5e-26 Smith-Waterman score: 852; 40.2% identity (66.7% similar) in 381 aa overlap (42-410:10-379) 20 30 40 50 60 70 pF1KE0 SSCSSVTASAAPGTASLVPDYWIDGSNRDALSDFFEVESELGRGATSIVYRCKQKGTQKP ..: ... :::.:: :.: :: . : . CCDS54 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQE 10 20 30 80 90 100 110 120 pF1KE0 YALKVL--KKTV--DKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELF :: :.. :: :.. .. : . :.::::..:.. . ::..:::::::: CCDS54 YAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELF 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 DRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFG . :: . :::: ::. ..::::.: . : :::::::::::::: :. . : .:.:::: CCDS54 EDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFG 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE0 LSKIVE-HQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERG :. :. : ::::: .::.:: :: ::::. :.: :::: :. ::.:: CCDS54 LAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDE-- 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE0 DQF-MFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWVTGKA- :: ....: : : :: :: :. .::::. :.....: ::.:. .::.:::. .. CCDS54 DQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRST 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE0 -ANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSRLGSASSSHGSIQESHKASRDPSPIQ :...: . . :..::::::::.:. ... ..: ::..: . .. : .. : .: CCDS54 VASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAAKSLLKKPDGVKKRKSSSSVQ 280 290 300 310 320 330 370 380 390 400 410 pF1KE0 --DGNEDMKAIPEGEKIQGDGAQAAVKGAQAELMKV--QALEKVKGADINAEEAPKMVPK ...:. .. : : ::. . :..:: : .: ....:..: CCDS54 MMESTESSNTTIEDED---------VKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGL 340 350 360 370 380 420 430 440 450 460 470 pF1KE0 AVEDGIKVADLELEEGLAEEKLKTVEEAAAPREGQGSSAVGFEVPQQDVILPEY CCDS54 TAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQY 390 400 410 420 430 440 >>CCDS47127.1 CAMK2D gene_id:817|Hs108|chr4 (492 aa) initn: 748 init1: 422 opt: 851 Z-score: 589.3 bits: 118.4 E(32554): 1.7e-26 Smith-Waterman score: 851; 39.3% identity (66.7% similar) in 384 aa overlap (42-410:10-382) 20 30 40 50 60 70 pF1KE0 SSCSSVTASAAPGTASLVPDYWIDGSNRDALSDFFEVESELGRGATSIVYRCKQKGTQKP ..: ... :::.:: :.: :: . : . CCDS47 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQE 10 20 30 80 90 100 110 120 pF1KE0 YALKVL--KKTV--DKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELF :: :.. :: :.. .. : . :.::::..:.. . ::..:::::::: CCDS47 YAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELF 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 DRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFG . :: . :::: ::. ..::::.: . : :::::::::::::: :. . : .:.:::: CCDS47 EDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFG 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE0 LSKIVE-HQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERG :. :. : ::::: .::.:: :: ::::. :.: :::: :. ::.:: CCDS47 LAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDE-- 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE0 DQF-MFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWVTGKA- :: ....: : : :: :: :. .::::. :.....: ::.:. .::.:::. .. CCDS47 DQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRST 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE0 -ANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSRLGSASSSHGSIQESHKASRDPSPIQ :...: . . :..::::::::.:. ... ..: ::..: . :. .. CCDS47 VASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAAKS---------LLKKPDGVK 280 290 300 310 320 370 380 390 400 410 pF1KE0 DGNEDMKAIPEGEKIQGDGAQAA-----VKGAQAELMKV--QALEKVKGADINAEEAPKM . . . :.:.: . ...... ::. . :..:: : .: ....:..: CCDS47 EPQTTVIHNPDGNKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICD 330 340 350 360 370 380 420 430 440 450 460 470 pF1KE0 VPKAVEDGIKVADLELEEGLAEEKLKTVEEAAAPREGQGSSAVGFEVPQQDVILPEY CCDS47 PGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRL 390 400 410 420 430 440 >>CCDS43263.1 CAMK2D gene_id:817|Hs108|chr4 (478 aa) initn: 599 init1: 427 opt: 847 Z-score: 586.8 bits: 117.9 E(32554): 2.3e-26 Smith-Waterman score: 847; 42.9% identity (67.8% similar) in 338 aa overlap (42-371:10-345) 20 30 40 50 60 70 pF1KE0 SSCSSVTASAAPGTASLVPDYWIDGSNRDALSDFFEVESELGRGATSIVYRCKQKGTQKP ..: ... :::.:: :.: :: . : . CCDS43 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQE 10 20 30 80 90 100 110 120 pF1KE0 YALKVL--KKTV--DKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELF :: :.. :: :.. .. : . :.::::..:.. . ::..:::::::: CCDS43 YAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELF 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 DRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFG . :: . :::: ::. ..::::.: . : :::::::::::::: :. . : .:.:::: CCDS43 EDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFG 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE0 LSKIVE-HQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERG :. :. : ::::: .::.:: :: ::::. :.: :::: :. ::.:: CCDS43 LAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDE-- 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE0 DQF-MFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWVTGKA- :: ....: : : :: :: :. .::::. :.....: ::.:. .::.:::. .. CCDS43 DQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRST 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE0 -ANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSRLGSASSSHGSIQESHKASRDPSPIQ :...: . . :..::::::::.:. ... ..: ::..: . .. : : . : CCDS43 VASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTT 280 290 300 310 320 330 370 380 390 400 410 420 pF1KE0 DGNEDMKAIPEGEKIQGDGAQAAVKGAQAELMKVQALEKVKGADINAEEAPKMVPKAVED .::.:: CCDS43 IEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRF 340 350 360 370 380 390 473 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:41:07 2016 done: Sat Nov 5 04:41:07 2016 Total Scan time: 2.870 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]