FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0954, 482 aa 1>>>pF1KE0954 482 - 482 aa - 482 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.8656+/-0.000466; mu= -16.3788+/- 0.029 mean_var=584.3285+/-126.981, 0's: 0 Z-trim(123.3): 1738 B-trim: 0 in 0/56 Lambda= 0.053057 statistics sampled from 40414 (42762) to 40414 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.791), E-opt: 0.2 (0.501), width: 16 Scan time: 11.580 The best scores are: opt bits E(85289) NP_003943 (OMIM: 608939) ribosomal protein S6 kina ( 482) 3278 265.7 2e-70 XP_005274221 (OMIM: 608939) PREDICTED: ribosomal p ( 385) 2634 216.3 1.2e-55 NP_001258989 (OMIM: 608938) ribosomal protein S6 k ( 502) 2219 184.7 5.2e-46 NP_003152 (OMIM: 608938) ribosomal protein S6 kina ( 525) 2219 184.7 5.4e-46 NP_001258973 (OMIM: 608938) ribosomal protein S6 k ( 472) 2182 181.8 3.5e-45 NP_001258972 (OMIM: 608938) ribosomal protein S6 k ( 451) 2165 180.5 8.5e-45 XP_005274222 (OMIM: 608939) PREDICTED: ribosomal p ( 282) 1970 165.4 1.9e-40 XP_016873597 (OMIM: 608939) PREDICTED: ribosomal p ( 282) 1970 165.4 1.9e-40 XP_006718720 (OMIM: 608939) PREDICTED: ribosomal p ( 282) 1970 165.4 1.9e-40 XP_006718719 (OMIM: 608939) PREDICTED: ribosomal p ( 282) 1970 165.4 1.9e-40 XP_006718718 (OMIM: 608939) PREDICTED: ribosomal p ( 282) 1970 165.4 1.9e-40 NP_001258971 (OMIM: 608938) ribosomal protein S6 k ( 502) 1895 159.9 1.5e-38 XP_011523404 (OMIM: 608938) PREDICTED: ribosomal p ( 391) 1756 149.1 2e-35 XP_011523403 (OMIM: 608938) PREDICTED: ribosomal p ( 489) 1752 148.9 2.9e-35 XP_016880418 (OMIM: 608938) PREDICTED: ribosomal p ( 436) 1715 146.1 1.9e-34 XP_016880420 (OMIM: 608938) PREDICTED: ribosomal p ( 322) 1448 125.5 2.2e-28 XP_011523405 (OMIM: 608938) PREDICTED: ribosomal p ( 322) 1448 125.5 2.2e-28 XP_016880419 (OMIM: 608938) PREDICTED: ribosomal p ( 322) 1448 125.5 2.2e-28 XP_016880421 (OMIM: 608938) PREDICTED: ribosomal p ( 322) 1448 125.5 2.2e-28 NP_001305865 (OMIM: 601685) ribosomal protein S6 k ( 758) 1277 112.8 3.5e-24 NP_001006933 (OMIM: 601685) ribosomal protein S6 k ( 741) 1241 110.0 2.3e-23 NP_066958 (OMIM: 601685) ribosomal protein S6 kina ( 733) 1240 109.9 2.4e-23 NP_002944 (OMIM: 601684) ribosomal protein S6 kina ( 735) 1235 109.6 3.2e-23 XP_006715612 (OMIM: 601685) PREDICTED: ribosomal p ( 761) 1235 109.6 3.3e-23 XP_006724570 (OMIM: 300075,300844,303600) PREDICTE ( 711) 1227 108.9 4.7e-23 XP_016885208 (OMIM: 300075,300844,303600) PREDICTE ( 711) 1227 108.9 4.7e-23 XP_011543865 (OMIM: 300075,300844,303600) PREDICTE ( 712) 1227 108.9 4.8e-23 XP_016885206 (OMIM: 300075,300844,303600) PREDICTE ( 712) 1227 108.9 4.8e-23 XP_016885204 (OMIM: 300075,300844,303600) PREDICTE ( 712) 1227 108.9 4.8e-23 XP_016885202 (OMIM: 300075,300844,303600) PREDICTE ( 712) 1227 108.9 4.8e-23 XP_016885205 (OMIM: 300075,300844,303600) PREDICTE ( 712) 1227 108.9 4.8e-23 XP_016885203 (OMIM: 300075,300844,303600) PREDICTE ( 712) 1227 108.9 4.8e-23 XP_005274630 (OMIM: 300075,300844,303600) PREDICTE ( 739) 1227 108.9 4.9e-23 NP_004577 (OMIM: 300075,300844,303600) ribosomal p ( 740) 1227 108.9 4.9e-23 XP_005274634 (OMIM: 300075,300844,303600) PREDICTE ( 710) 1225 108.8 5.3e-23 XP_016885207 (OMIM: 300075,300844,303600) PREDICTE ( 711) 1225 108.8 5.3e-23 NP_001317370 (OMIM: 601684) ribosomal protein S6 k ( 719) 1225 108.8 5.3e-23 NP_001006666 (OMIM: 601684) ribosomal protein S6 k ( 744) 1223 108.6 6.1e-23 XP_011543863 (OMIM: 300075,300844,303600) PREDICTE ( 718) 1208 107.5 1.3e-22 XP_011543862 (OMIM: 300075,300844,303600) PREDICTE ( 718) 1208 107.5 1.3e-22 XP_011543861 (OMIM: 300075,300844,303600) PREDICTE ( 718) 1208 107.5 1.3e-22 XP_011543860 (OMIM: 300075,300844,303600) PREDICTE ( 718) 1208 107.5 1.3e-22 XP_011543859 (OMIM: 300075,300844,303600) PREDICTE ( 718) 1208 107.5 1.3e-22 XP_011543858 (OMIM: 300075,300844,303600) PREDICTE ( 745) 1208 107.5 1.3e-22 XP_011543857 (OMIM: 300075,300844,303600) PREDICTE ( 746) 1208 107.5 1.3e-22 XP_011543864 (OMIM: 300075,300844,303600) PREDICTE ( 717) 1206 107.3 1.5e-22 NP_055311 (OMIM: 300303) ribosomal protein S6 kina ( 745) 1200 106.9 2.1e-22 NP_001317441 (OMIM: 300303) ribosomal protein S6 k ( 745) 1197 106.6 2.4e-22 XP_011529219 (OMIM: 300303) PREDICTED: ribosomal p ( 745) 1197 106.6 2.4e-22 XP_016884913 (OMIM: 300303) PREDICTED: ribosomal p ( 762) 1197 106.7 2.4e-22 >>NP_003943 (OMIM: 608939) ribosomal protein S6 kinase b (482 aa) initn: 3278 init1: 3278 opt: 3278 Z-score: 1385.3 bits: 265.7 E(85289): 2e-70 Smith-Waterman score: 3278; 99.8% identity (100.0% similar) in 482 aa overlap (1-482:1-482) 10 20 30 40 50 60 pF1KE0 MAAVFDLDLETEEGSEGEGEPELSPADACPLAELRAAGLEPVGHYEEVELTETSVNVGPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MAAVFDLDLETEEGSEGEGEPELSPADACPLAELRAAGLEPVGHYEEVELTETSVNVGPE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 RIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAER 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 NILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 NILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 LVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 KKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 KKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFDT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 RFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. NP_003 RFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 PVSPLKFSPFEGFRPSPSLPEPTELPLPPLLPPPPPSTTAPLPIRPPSGTKKSKRGRGRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PVSPLKFSPFEGFRPSPSLPEPTELPLPPLLPPPPPSTTAPLPIRPPSGTKKSKRGRGRP 430 440 450 460 470 480 pF1KE0 GR :: NP_003 GR >>XP_005274221 (OMIM: 608939) PREDICTED: ribosomal prote (385 aa) initn: 2634 init1: 2634 opt: 2634 Z-score: 1120.1 bits: 216.3 E(85289): 1.2e-55 Smith-Waterman score: 2634; 99.7% identity (100.0% similar) in 385 aa overlap (98-482:1-385) 70 80 90 100 110 120 pF1KE0 ELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVK :::::::::::::::::::::::::::::: XP_005 MKVLRKAKIVRNAKDTAHTRAERNILESVK 10 20 30 130 140 150 160 170 180 pF1KE0 HPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHS 40 50 60 70 80 90 190 200 210 220 230 240 pF1KE0 QGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHN 100 110 120 130 140 150 250 260 270 280 290 300 pF1KE0 RAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKRN 160 170 180 190 200 210 310 320 330 340 350 360 pF1KE0 PSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFDTRFTRQTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFDTRFTRQTP 220 230 240 250 260 270 370 380 390 400 410 420 pF1KE0 VDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRVPVSPLKF ::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::: XP_005 VDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRAPVSPLKF 280 290 300 310 320 330 430 440 450 460 470 480 pF1KE0 SPFEGFRPSPSLPEPTELPLPPLLPPPPPSTTAPLPIRPPSGTKKSKRGRGRPGR ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPFEGFRPSPSLPEPTELPLPPLLPPPPPSTTAPLPIRPPSGTKKSKRGRGRPGR 340 350 360 370 380 >>NP_001258989 (OMIM: 608938) ribosomal protein S6 kinas (502 aa) initn: 2285 init1: 2167 opt: 2219 Z-score: 947.0 bits: 184.7 E(85289): 5.2e-46 Smith-Waterman score: 2244; 70.4% identity (85.3% similar) in 490 aa overlap (1-474:1-486) 10 20 30 40 50 pF1KE0 MAAVFDLDLETEEGSEGEGEPELSPADACPLAE-LRAAGLEP--VG--HYEEVELTETSV ::.:::.::. : . .: : : .. : : . .:. : .: : :. :..:::: NP_001 MAGVFDIDLDQPEDAGSEDELE----EGGQLNESMDHGGVGPYELGMEHCEKFEISETSV 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 NVGPERIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAH : :::.: :.:::::::::::::::::::::: :.: :::.:::::.:: :::::::::: NP_001 NRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAH 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 TRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYL :.::::::: :::::::.: :::::::::::::: ::::::: .:::::::.:::::::: NP_001 TKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYL 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 AEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEY :::..::::::..::::::::::::::. :::.:::::::::::::.:.::::::::::: NP_001 AEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEY 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 MAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPD ::::::.:::::::::::::::::::::::.::::.::::::.:::.. :: :::::: . NP_001 MAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQE 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 ARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDV ::::.::.:::: ..:.:.:::::..:: ::::::.::..::: .:.:::.: ::::::: NP_001 ARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDV 300 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 SQFDTRFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLN ::::..::::::::::::..:::::::.::::::::::::.:.:: :::.::.:::::. NP_001 SQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSFEPKIRSPRRFI 360 370 380 390 400 410 420 430 440 450 460 pF1KE0 SSPRVPVSPLKFSP--FEGFRPSPSL--PE-PTELPLPP-----LLPPPPPSTTAPLPIR .:::.::::.:::: : : : : :. :.: :. . ..:::::: NP_001 GSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSGIEQMDVTMSGEASAPLPIR 420 430 440 450 460 470 470 480 pF1KE0 PP-SGTKKSKRGRGRPGR : :: :.. NP_001 QPNSGPYKKQAFPMISKRPEHLRMNL 480 490 500 >>NP_003152 (OMIM: 608938) ribosomal protein S6 kinase b (525 aa) initn: 2285 init1: 2167 opt: 2219 Z-score: 946.8 bits: 184.7 E(85289): 5.4e-46 Smith-Waterman score: 2244; 70.4% identity (85.3% similar) in 490 aa overlap (1-474:24-509) 10 20 30 pF1KE0 MAAVFDLDLETEEGSEGEGEPELSPADACPLAE-LRA ::.:::.::. : . .: : : .. : : . NP_003 MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELE----EGGQLNESMDH 10 20 30 40 50 40 50 60 70 80 90 pF1KE0 AGLEP--VG--HYEEVELTETSVNVGPERIGPHCFELLRVLGKGGYGKVFQVRKVQGTNL .:. : .: : :. :..::::: :::.: :.:::::::::::::::::::::: :.: NP_003 GGVGPYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANT 60 70 80 90 100 110 100 110 120 130 140 150 pF1KE0 GKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLS :::.:::::.:: :::::::::::.::::::: :::::::.: :::::::::::::: :: NP_003 GKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLS 120 130 140 150 160 170 160 170 180 190 200 210 pF1KE0 GGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTD ::::: .:::::::.:::::::::::..::::::..::::::::::::::. :::.:::: NP_003 GGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTD 180 190 200 210 220 230 220 230 240 250 260 270 pF1KE0 FGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAE :::::::::.:.:::::::::::::::::.:::::::::::::::::::::::.::::.: NP_003 FGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGE 240 250 260 270 280 290 280 290 300 310 320 330 pF1KE0 NRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMN :::::.:::.. :: :::::: .::::.::.:::: ..:.:.:::::..:: ::::::.: NP_003 NRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHIN 300 310 320 330 340 350 340 350 360 370 380 390 pF1KE0 WDDLLAWRVDPPFRPCLQSEEDVSQFDTRFTRQTPVDSPDDTALSESANQAFLGFTYVAP :..::: .:.:::.: :::::::::::..::::::::::::..:::::::.::::::::: NP_003 WEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAP 360 370 380 390 400 410 400 410 420 430 440 pF1KE0 SVLDSIKEGFSFQPKLRSPRRLNSSPRVPVSPLKFSP--FEGFRPSPSL--PE-PTELPL :::.:.:: :::.::.:::::. .:::.::::.:::: : : : : :. :.: :. NP_003 SVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPM 420 430 440 450 460 470 450 460 470 480 pF1KE0 PP-----LLPPPPPSTTAPLPIRPP-SGTKKSKRGRGRPGR . ..:::::: : :: :.. NP_003 ETSGIEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL 480 490 500 510 520 >>NP_001258973 (OMIM: 608938) ribosomal protein S6 kinas (472 aa) initn: 2205 init1: 2167 opt: 2182 Z-score: 932.1 bits: 181.8 E(85289): 3.5e-45 Smith-Waterman score: 2207; 73.9% identity (87.9% similar) in 448 aa overlap (38-474:12-456) 10 20 30 40 50 60 pF1KE0 DLETEEGSEGEGEPELSPADACPLAELRAAGLEPVGHYEEVELTETSVNVGPERIGPHCF :.: : :. :..::::: :::.: :.:: NP_001 MDHGGVGPYELGME---HCEKFEISETSVNRGPEKIRPECF 10 20 30 70 80 90 100 110 120 pF1KE0 ELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVK :::::::::::::::::::: :.: :::.:::::.:: :::::::::::.::::::: :: NP_001 ELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVK 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 HPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHS :::::.: :::::::::::::: ::::::: .:::::::.:::::::::::..::::::. NP_001 HPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQ 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE0 QGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHN .::::::::::::::. :::.:::::::::::::.:.:::::::::::::::::.::::: NP_001 KGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHN 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE0 RAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKRN ::::::::::::::::::.::::.::::::.:::.. :: :::::: .::::.::.:::: NP_001 RAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRN 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE0 PSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFDTRFTRQTP ..:.:.:::::..:: ::::::.::..::: .:.:::.: :::::::::::..:::::: NP_001 AASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTP 280 290 300 310 320 330 370 380 390 400 410 420 pF1KE0 VDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRVPVSPLKF ::::::..:::::::.::::::::::::.:.:: :::.::.:::::. .:::.::::.:: NP_001 VDSPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKF 340 350 360 370 380 390 430 440 450 460 470 pF1KE0 SP--FEGFRPSPSL--PE-PTELPLPP-----LLPPPPPSTTAPLPIRPP-SGTKKSKRG :: : : : : :. :.: :. . ..:::::: : :: :.. NP_001 SPGDFWGRGASASTANPQTPVEYPMETSGIEQMDVTMSGEASAPLPIRQPNSGPYKKQAF 400 410 420 430 440 450 480 pF1KE0 RGRPGR NP_001 PMISKRPEHLRMNL 460 470 >>NP_001258972 (OMIM: 608938) ribosomal protein S6 kinas (451 aa) initn: 2207 init1: 2127 opt: 2165 Z-score: 925.3 bits: 180.5 E(85289): 8.5e-45 Smith-Waterman score: 2165; 75.2% identity (90.2% similar) in 428 aa overlap (1-423:24-447) 10 20 30 pF1KE0 MAAVFDLDLETEEGSEGEGEPELSPADACPLAE-LRA ::.:::.::. : . .: : : .. : : . NP_001 MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELE----EGGQLNESMDH 10 20 30 40 50 40 50 60 70 80 90 pF1KE0 AGLEP--VG--HYEEVELTETSVNVGPERIGPHCFELLRVLGKGGYGKVFQVRKVQGTNL .:. : .: : :. :..::::: :::.: :.:::::::::::::::::::::: :.: NP_001 GGVGPYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANT 60 70 80 90 100 110 100 110 120 130 140 150 pF1KE0 GKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLS :::.:::::.:: :::::::::::.::::::: :::::::.: :::::::::::::: :: NP_001 GKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLS 120 130 140 150 160 170 160 170 180 190 200 210 pF1KE0 GGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTD ::::: .:::::::.:::::::::::..::::::..::::::::::::::. :::.:::: NP_001 GGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTD 180 190 200 210 220 230 220 230 240 250 260 270 pF1KE0 FGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAE :::::::::.:.:::::::::::::::::.:::::::::::::::::::::::.::::.: NP_001 FGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGE 240 250 260 270 280 290 280 290 300 310 320 330 pF1KE0 NRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMN :::::.:::.. :: :::::: .::::.::.:::: ..:.:.:::::..:: ::::::.: NP_001 NRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHIN 300 310 320 330 340 350 340 350 360 370 380 390 pF1KE0 WDDLLAWRVDPPFRPCLQSEEDVSQFDTRFTRQTPVDSPDDTALSESANQAFLGFTYVAP :..::: .:.:::.: :::::::::::..::::::::::::..:::::::.::::::::: NP_001 WEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAP 360 370 380 390 400 410 400 410 420 430 440 450 pF1KE0 SVLDSIKEGFSFQPKLRSPRRLNSSPRVPVSPLKFSPFEGFRPSPSLPEPTELPLPPLLP :::.:.:: :::.::.:::::. .:::.::: NP_001 SVLESVKEKFSFEPKIRSPRRFIGSPRTPVSTAMC 420 430 440 450 460 470 480 pF1KE0 PPPPSTTAPLPIRPPSGTKKSKRGRGRPGR >>XP_005274222 (OMIM: 608939) PREDICTED: ribosomal prote (282 aa) initn: 1970 init1: 1970 opt: 1970 Z-score: 847.1 bits: 165.4 E(85289): 1.9e-40 Smith-Waterman score: 1970; 99.6% identity (100.0% similar) in 282 aa overlap (201-482:1-282) 180 190 200 210 220 230 pF1KE0 ACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFC :::::::::::::::::::::::::::::: XP_005 MLSSQGHIKLTDFGLCKESIHEGAVTHTFC 10 20 30 240 250 260 270 280 290 pF1KE0 GTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPP 40 50 60 70 80 90 300 310 320 330 340 350 pF1KE0 YLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQ 100 110 120 130 140 150 360 370 380 390 400 410 pF1KE0 SEEDVSQFDTRFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SEEDVSQFDTRFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRS 160 170 180 190 200 210 420 430 440 450 460 470 pF1KE0 PRRLNSSPRVPVSPLKFSPFEGFRPSPSLPEPTELPLPPLLPPPPPSTTAPLPIRPPSGT :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PRRLNSSPRAPVSPLKFSPFEGFRPSPSLPEPTELPLPPLLPPPPPSTTAPLPIRPPSGT 220 230 240 250 260 270 480 pF1KE0 KKSKRGRGRPGR :::::::::::: XP_005 KKSKRGRGRPGR 280 >>XP_016873597 (OMIM: 608939) PREDICTED: ribosomal prote (282 aa) initn: 1970 init1: 1970 opt: 1970 Z-score: 847.1 bits: 165.4 E(85289): 1.9e-40 Smith-Waterman score: 1970; 99.6% identity (100.0% similar) in 282 aa overlap (201-482:1-282) 180 190 200 210 220 230 pF1KE0 ACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFC :::::::::::::::::::::::::::::: XP_016 MLSSQGHIKLTDFGLCKESIHEGAVTHTFC 10 20 30 240 250 260 270 280 290 pF1KE0 GTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPP 40 50 60 70 80 90 300 310 320 330 340 350 pF1KE0 YLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQ 100 110 120 130 140 150 360 370 380 390 400 410 pF1KE0 SEEDVSQFDTRFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEEDVSQFDTRFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRS 160 170 180 190 200 210 420 430 440 450 460 470 pF1KE0 PRRLNSSPRVPVSPLKFSPFEGFRPSPSLPEPTELPLPPLLPPPPPSTTAPLPIRPPSGT :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PRRLNSSPRAPVSPLKFSPFEGFRPSPSLPEPTELPLPPLLPPPPPSTTAPLPIRPPSGT 220 230 240 250 260 270 480 pF1KE0 KKSKRGRGRPGR :::::::::::: XP_016 KKSKRGRGRPGR 280 >>XP_006718720 (OMIM: 608939) PREDICTED: ribosomal prote (282 aa) initn: 1970 init1: 1970 opt: 1970 Z-score: 847.1 bits: 165.4 E(85289): 1.9e-40 Smith-Waterman score: 1970; 99.6% identity (100.0% similar) in 282 aa overlap (201-482:1-282) 180 190 200 210 220 230 pF1KE0 ACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFC :::::::::::::::::::::::::::::: XP_006 MLSSQGHIKLTDFGLCKESIHEGAVTHTFC 10 20 30 240 250 260 270 280 290 pF1KE0 GTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPP 40 50 60 70 80 90 300 310 320 330 340 350 pF1KE0 YLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQ 100 110 120 130 140 150 360 370 380 390 400 410 pF1KE0 SEEDVSQFDTRFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SEEDVSQFDTRFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRS 160 170 180 190 200 210 420 430 440 450 460 470 pF1KE0 PRRLNSSPRVPVSPLKFSPFEGFRPSPSLPEPTELPLPPLLPPPPPSTTAPLPIRPPSGT :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PRRLNSSPRAPVSPLKFSPFEGFRPSPSLPEPTELPLPPLLPPPPPSTTAPLPIRPPSGT 220 230 240 250 260 270 480 pF1KE0 KKSKRGRGRPGR :::::::::::: XP_006 KKSKRGRGRPGR 280 >>XP_006718719 (OMIM: 608939) PREDICTED: ribosomal prote (282 aa) initn: 1970 init1: 1970 opt: 1970 Z-score: 847.1 bits: 165.4 E(85289): 1.9e-40 Smith-Waterman score: 1970; 99.6% identity (100.0% similar) in 282 aa overlap (201-482:1-282) 180 190 200 210 220 230 pF1KE0 ACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFC :::::::::::::::::::::::::::::: XP_006 MLSSQGHIKLTDFGLCKESIHEGAVTHTFC 10 20 30 240 250 260 270 280 290 pF1KE0 GTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPP 40 50 60 70 80 90 300 310 320 330 340 350 pF1KE0 YLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQ 100 110 120 130 140 150 360 370 380 390 400 410 pF1KE0 SEEDVSQFDTRFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SEEDVSQFDTRFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRS 160 170 180 190 200 210 420 430 440 450 460 470 pF1KE0 PRRLNSSPRVPVSPLKFSPFEGFRPSPSLPEPTELPLPPLLPPPPPSTTAPLPIRPPSGT :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PRRLNSSPRAPVSPLKFSPFEGFRPSPSLPEPTELPLPPLLPPPPPSTTAPLPIRPPSGT 220 230 240 250 260 270 480 pF1KE0 KKSKRGRGRPGR :::::::::::: XP_006 KKSKRGRGRPGR 280 482 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:42:32 2016 done: Sat Nov 5 04:42:34 2016 Total Scan time: 11.580 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]