FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0959, 499 aa 1>>>pF1KE0959 499 - 499 aa - 499 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.0886+/-0.000916; mu= 2.9002+/- 0.055 mean_var=315.3713+/-68.593, 0's: 0 Z-trim(116.2): 451 B-trim: 481 in 1/53 Lambda= 0.072221 statistics sampled from 16237 (16781) to 16237 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.812), E-opt: 0.2 (0.515), width: 16 Scan time: 3.920 The best scores are: opt bits E(32554) CCDS10486.1 PKMYT1 gene_id:9088|Hs108|chr16 ( 499) 3504 378.6 8.6e-105 CCDS58414.1 PKMYT1 gene_id:9088|Hs108|chr16 ( 490) 3444 372.4 6.4e-103 CCDS45391.1 PKMYT1 gene_id:9088|Hs108|chr16 ( 480) 3107 337.2 2.4e-92 CCDS58415.1 PKMYT1 gene_id:9088|Hs108|chr16 ( 430) 2974 323.3 3.3e-88 >>CCDS10486.1 PKMYT1 gene_id:9088|Hs108|chr16 (499 aa) initn: 3504 init1: 3504 opt: 3504 Z-score: 1994.9 bits: 378.6 E(32554): 8.6e-105 Smith-Waterman score: 3504; 100.0% identity (100.0% similar) in 499 aa overlap (1-499:1-499) 10 20 30 40 50 60 pF1KE0 MLERPPALAMPMPTEGTPPPLSGTPIPVPAYFRHAEPGFSLKRPRGLSRSLPPPPPAKGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MLERPPALAMPMPTEGTPPPLSGTPIPVPAYFRHAEPGFSLKRPRGLSRSLPPPPPAKGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 IPISRLFPPRTPGWHQLQPRRVSFRGEASETLQSPGYDPSRPESFFQQSFQRLSRLGHGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 IPISRLFPPRTPGWHQLQPRRVSFRGEASETLQSPGYDPSRPESFFQQSFQRLSRLGHGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 YGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVGSHEKVGQHPCCVRLEQAWEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 YGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVGSHEKVGQHPCCVRLEQAWEEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 GILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALAHLHSQGLVHLDVKPANIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 GILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALAHLHSQGLVHLDVKPANIF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 LGPRGRCKLGDFGLLVELGTAGAGEVQEGDPRYMAPELLQGSYGTAADVFSLGLTILEVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 LGPRGRCKLGDFGLLVELGTAGAGEVQEGDPRYMAPELLQGSYGTAADVFSLGLTILEVA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 CNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLVMMLEPDPKLRATAEALLALPVLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 CNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLVMMLEPDPKLRATAEALLALPVLR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 QPRAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASWLQPLGPPATPPGSPPCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 QPRAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASWLQPLGPPATPPGSPPCS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 LLLDSSLSSNWDDDSLGPSLSPEAVLARTVGSTSTPRSRCTPRDALDLSDINSEPPRGSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 LLLDSSLSSNWDDDSLGPSLSPEAVLARTVGSTSTPRSRCTPRDALDLSDINSEPPRGSF 430 440 450 460 470 480 490 pF1KE0 PSFEPRNLLSLFEDTLDPT ::::::::::::::::::: CCDS10 PSFEPRNLLSLFEDTLDPT 490 >>CCDS58414.1 PKMYT1 gene_id:9088|Hs108|chr16 (490 aa) initn: 3444 init1: 3444 opt: 3444 Z-score: 1961.2 bits: 372.4 E(32554): 6.4e-103 Smith-Waterman score: 3444; 100.0% identity (100.0% similar) in 490 aa overlap (10-499:1-490) 10 20 30 40 50 60 pF1KE0 MLERPPALAMPMPTEGTPPPLSGTPIPVPAYFRHAEPGFSLKRPRGLSRSLPPPPPAKGS ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MPMPTEGTPPPLSGTPIPVPAYFRHAEPGFSLKRPRGLSRSLPPPPPAKGS 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 IPISRLFPPRTPGWHQLQPRRVSFRGEASETLQSPGYDPSRPESFFQQSFQRLSRLGHGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 IPISRLFPPRTPGWHQLQPRRVSFRGEASETLQSPGYDPSRPESFFQQSFQRLSRLGHGS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 YGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVGSHEKVGQHPCCVRLEQAWEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 YGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVGSHEKVGQHPCCVRLEQAWEEG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 GILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALAHLHSQGLVHLDVKPANIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 GILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALAHLHSQGLVHLDVKPANIF 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE0 LGPRGRCKLGDFGLLVELGTAGAGEVQEGDPRYMAPELLQGSYGTAADVFSLGLTILEVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LGPRGRCKLGDFGLLVELGTAGAGEVQEGDPRYMAPELLQGSYGTAADVFSLGLTILEVA 240 250 260 270 280 290 310 320 330 340 350 360 pF1KE0 CNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLVMMLEPDPKLRATAEALLALPVLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 CNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLVMMLEPDPKLRATAEALLALPVLR 300 310 320 330 340 350 370 380 390 400 410 420 pF1KE0 QPRAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASWLQPLGPPATPPGSPPCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 QPRAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASWLQPLGPPATPPGSPPCS 360 370 380 390 400 410 430 440 450 460 470 480 pF1KE0 LLLDSSLSSNWDDDSLGPSLSPEAVLARTVGSTSTPRSRCTPRDALDLSDINSEPPRGSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LLLDSSLSSNWDDDSLGPSLSPEAVLARTVGSTSTPRSRCTPRDALDLSDINSEPPRGSF 420 430 440 450 460 470 490 pF1KE0 PSFEPRNLLSLFEDTLDPT ::::::::::::::::::: CCDS58 PSFEPRNLLSLFEDTLDPT 480 490 >>CCDS45391.1 PKMYT1 gene_id:9088|Hs108|chr16 (480 aa) initn: 3164 init1: 3107 opt: 3107 Z-score: 1771.5 bits: 337.2 E(32554): 2.4e-92 Smith-Waterman score: 3107; 99.3% identity (99.5% similar) in 442 aa overlap (1-442:1-442) 10 20 30 40 50 60 pF1KE0 MLERPPALAMPMPTEGTPPPLSGTPIPVPAYFRHAEPGFSLKRPRGLSRSLPPPPPAKGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MLERPPALAMPMPTEGTPPPLSGTPIPVPAYFRHAEPGFSLKRPRGLSRSLPPPPPAKGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 IPISRLFPPRTPGWHQLQPRRVSFRGEASETLQSPGYDPSRPESFFQQSFQRLSRLGHGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 IPISRLFPPRTPGWHQLQPRRVSFRGEASETLQSPGYDPSRPESFFQQSFQRLSRLGHGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 YGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVGSHEKVGQHPCCVRLEQAWEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 YGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVGSHEKVGQHPCCVRLEQAWEEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 GILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALAHLHSQGLVHLDVKPANIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 GILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALAHLHSQGLVHLDVKPANIF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 LGPRGRCKLGDFGLLVELGTAGAGEVQEGDPRYMAPELLQGSYGTAADVFSLGLTILEVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 LGPRGRCKLGDFGLLVELGTAGAGEVQEGDPRYMAPELLQGSYGTAADVFSLGLTILEVA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 CNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLVMMLEPDPKLRATAEALLALPVLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 CNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLVMMLEPDPKLRATAEALLALPVLR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 QPRAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASWLQPLGPPATPPGSPPCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 QPRAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASWLQPLGPPATPPGSPPCS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 LLLDSSLSSNWDDDSLGPSLSPEAVLARTVGSTSTPRSRCTPRDALDLSDINSEPPRGSF ::::::::::::::::::. : CCDS45 LLLDSSLSSNWDDDSLGPGHPPCLACPPAGLHSPLRLSWPGLWGAPPPPGAGAHPGMPWT 430 440 450 460 470 480 >>CCDS58415.1 PKMYT1 gene_id:9088|Hs108|chr16 (430 aa) initn: 2974 init1: 2974 opt: 2974 Z-score: 1697.2 bits: 323.3 E(32554): 3.3e-88 Smith-Waterman score: 2974; 100.0% identity (100.0% similar) in 426 aa overlap (74-499:5-430) 50 60 70 80 90 100 pF1KE0 PRGLSRSLPPPPPAKGSIPISRLFPPRTPGWHQLQPRRVSFRGEASETLQSPGYDPSRPE :::::::::::::::::::::::::::::: CCDS58 MLERWHQLQPRRVSFRGEASETLQSPGYDPSRPE 10 20 30 110 120 130 140 150 160 pF1KE0 SFFQQSFQRLSRLGHGSYGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVGSHEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SFFQQSFQRLSRLGHGSYGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVGSHEK 40 50 60 70 80 90 170 180 190 200 210 220 pF1KE0 VGQHPCCVRLEQAWEEGGILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VGQHPCCVRLEQAWEEGGILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALAH 100 110 120 130 140 150 230 240 250 260 270 280 pF1KE0 LHSQGLVHLDVKPANIFLGPRGRCKLGDFGLLVELGTAGAGEVQEGDPRYMAPELLQGSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LHSQGLVHLDVKPANIFLGPRGRCKLGDFGLLVELGTAGAGEVQEGDPRYMAPELLQGSY 160 170 180 190 200 210 290 300 310 320 330 340 pF1KE0 GTAADVFSLGLTILEVACNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLVMMLEPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 GTAADVFSLGLTILEVACNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLVMMLEPD 220 230 240 250 260 270 350 360 370 380 390 400 pF1KE0 PKLRATAEALLALPVLRQPRAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PKLRATAEALLALPVLRQPRAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASW 280 290 300 310 320 330 410 420 430 440 450 460 pF1KE0 LQPLGPPATPPGSPPCSLLLDSSLSSNWDDDSLGPSLSPEAVLARTVGSTSTPRSRCTPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LQPLGPPATPPGSPPCSLLLDSSLSSNWDDDSLGPSLSPEAVLARTVGSTSTPRSRCTPR 340 350 360 370 380 390 470 480 490 pF1KE0 DALDLSDINSEPPRGSFPSFEPRNLLSLFEDTLDPT :::::::::::::::::::::::::::::::::::: CCDS58 DALDLSDINSEPPRGSFPSFEPRNLLSLFEDTLDPT 400 410 420 430 499 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:43:10 2016 done: Sat Nov 5 04:43:10 2016 Total Scan time: 3.920 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]