Result of FASTA (omim) for
pF1KE0959
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0959, 499 aa
1>>>pF1KE0959 499 - 499 aa - 499 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.2919+/-0.000418; mu= -7.9281+/- 0.026
mean_var=583.6108+/-128.167, 0's: 0 Z-trim(124.0): 725 B-trim: 33 in 1/57
Lambda= 0.053090
statistics sampled from 43529 (44921) to 43529 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.813), E-opt: 0.2 (0.527), width: 16
Scan time: 12.650
The best scores are: opt bits E(85289)
NP_004194 (OMIM: 602474) membrane-associated tyros ( 499) 3504 283.3 1.1e-75
XP_011521036 (OMIM: 602474) PREDICTED: membrane-as ( 499) 3504 283.3 1.1e-75
XP_011521037 (OMIM: 602474) PREDICTED: membrane-as ( 490) 3444 278.7 2.7e-74
NP_001245380 (OMIM: 602474) membrane-associated ty ( 490) 3444 278.7 2.7e-74
XP_011521038 (OMIM: 602474) PREDICTED: membrane-as ( 490) 3444 278.7 2.7e-74
NP_872629 (OMIM: 602474) membrane-associated tyros ( 480) 3107 252.9 1.5e-66
NP_001245379 (OMIM: 602474) membrane-associated ty ( 430) 2974 242.6 1.7e-63
NP_003943 (OMIM: 608939) ribosomal protein S6 kina ( 482) 400 45.5 0.0004
XP_011530307 (OMIM: 263520,604588) PREDICTED: seri ( 715) 387 44.8 0.001
NP_004064 (OMIM: 602913) serine/threonine-protein ( 646) 385 44.6 0.0011
NP_001186328 (OMIM: 263520,604588) serine/threonin (1189) 387 45.1 0.0014
NP_001186329 (OMIM: 263520,604588) serine/threonin (1214) 387 45.1 0.0014
XP_011530306 (OMIM: 263520,604588) PREDICTED: seri (1214) 387 45.1 0.0014
XP_006714291 (OMIM: 263520,604588) PREDICTED: seri (1227) 387 45.1 0.0014
NP_001186327 (OMIM: 263520,604588) serine/threonin (1242) 387 45.1 0.0014
NP_036356 (OMIM: 263520,604588) serine/threonine-p (1258) 387 45.1 0.0014
XP_011530305 (OMIM: 263520,604588) PREDICTED: seri (1258) 387 45.1 0.0014
NP_001186326 (OMIM: 263520,604588) serine/threonin (1286) 387 45.1 0.0014
XP_011523404 (OMIM: 608938) PREDICTED: ribosomal p ( 391) 370 43.1 0.0017
XP_016880418 (OMIM: 608938) PREDICTED: ribosomal p ( 436) 370 43.2 0.0019
NP_001258972 (OMIM: 608938) ribosomal protein S6 k ( 451) 370 43.2 0.0019
NP_001258973 (OMIM: 608938) ribosomal protein S6 k ( 472) 370 43.2 0.002
XP_011523403 (OMIM: 608938) PREDICTED: ribosomal p ( 489) 370 43.2 0.002
NP_001258989 (OMIM: 608938) ribosomal protein S6 k ( 502) 370 43.3 0.002
NP_003152 (OMIM: 608938) ribosomal protein S6 kina ( 525) 370 43.3 0.0021
XP_011532342 (OMIM: 601959) PREDICTED: serine/thre ( 671) 365 43.0 0.0031
NP_001139571 (OMIM: 604044) serine/threonine-prote ( 489) 361 42.6 0.0032
NP_002489 (OMIM: 604044) serine/threonine-protein ( 506) 361 42.6 0.0033
NP_689933 (OMIM: 604044) serine/threonine-protein ( 506) 361 42.6 0.0033
XP_006713373 (OMIM: 601959) PREDICTED: serine/thre ( 795) 365 43.1 0.0035
NP_598001 (OMIM: 606848) serine/threonine-protein ( 302) 354 41.7 0.0035
NP_064553 (OMIM: 608110) serine/threonine-protein ( 681) 363 42.9 0.0035
NP_001263646 (OMIM: 608110) serine/threonine-prote ( 681) 363 42.9 0.0035
XP_016862575 (OMIM: 601959) PREDICTED: serine/thre ( 824) 365 43.2 0.0036
NP_003148 (OMIM: 601959) serine/threonine-protein ( 841) 365 43.2 0.0036
XP_011532341 (OMIM: 601959) PREDICTED: serine/thre ( 842) 365 43.2 0.0036
XP_016862574 (OMIM: 601959) PREDICTED: serine/thre ( 870) 365 43.2 0.0037
NP_001159642 (OMIM: 604884) serine/threonine-prote ( 313) 345 41.1 0.0058
XP_006716999 (OMIM: 604884) PREDICTED: serine/thre ( 313) 345 41.1 0.0058
XP_005251721 (OMIM: 604884) PREDICTED: serine/thre ( 313) 345 41.1 0.0058
NP_001159640 (OMIM: 604884) serine/threonine-prote ( 313) 345 41.1 0.0058
NP_055212 (OMIM: 604884) serine/threonine-protein ( 313) 345 41.1 0.0058
NP_001159639 (OMIM: 604884) serine/threonine-prote ( 331) 345 41.1 0.006
NP_001159641 (OMIM: 604884) serine/threonine-prote ( 338) 345 41.1 0.006
NP_001138473 (OMIM: 604884) serine/threonine-prote ( 347) 345 41.1 0.0061
XP_016869706 (OMIM: 604884) PREDICTED: serine/thre ( 347) 345 41.1 0.0061
NP_001159643 (OMIM: 604884) serine/threonine-prote ( 347) 345 41.1 0.0061
XP_016883522 (OMIM: 604965,614868) PREDICTED: seri ( 388) 345 41.2 0.0066
XP_011527322 (OMIM: 604965,614868) PREDICTED: seri ( 404) 345 41.2 0.0067
XP_016869247 (OMIM: 605030) PREDICTED: serine/thre ( 456) 346 41.4 0.0068
>>NP_004194 (OMIM: 602474) membrane-associated tyrosine- (499 aa)
initn: 3504 init1: 3504 opt: 3504 Z-score: 1479.7 bits: 283.3 E(85289): 1.1e-75
Smith-Waterman score: 3504; 100.0% identity (100.0% similar) in 499 aa overlap (1-499:1-499)
10 20 30 40 50 60
pF1KE0 MLERPPALAMPMPTEGTPPPLSGTPIPVPAYFRHAEPGFSLKRPRGLSRSLPPPPPAKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MLERPPALAMPMPTEGTPPPLSGTPIPVPAYFRHAEPGFSLKRPRGLSRSLPPPPPAKGS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 IPISRLFPPRTPGWHQLQPRRVSFRGEASETLQSPGYDPSRPESFFQQSFQRLSRLGHGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IPISRLFPPRTPGWHQLQPRRVSFRGEASETLQSPGYDPSRPESFFQQSFQRLSRLGHGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 YGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVGSHEKVGQHPCCVRLEQAWEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVGSHEKVGQHPCCVRLEQAWEEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALAHLHSQGLVHLDVKPANIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALAHLHSQGLVHLDVKPANIF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LGPRGRCKLGDFGLLVELGTAGAGEVQEGDPRYMAPELLQGSYGTAADVFSLGLTILEVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LGPRGRCKLGDFGLLVELGTAGAGEVQEGDPRYMAPELLQGSYGTAADVFSLGLTILEVA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 CNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLVMMLEPDPKLRATAEALLALPVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 CNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLVMMLEPDPKLRATAEALLALPVLR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 QPRAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASWLQPLGPPATPPGSPPCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QPRAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASWLQPLGPPATPPGSPPCS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 LLLDSSLSSNWDDDSLGPSLSPEAVLARTVGSTSTPRSRCTPRDALDLSDINSEPPRGSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LLLDSSLSSNWDDDSLGPSLSPEAVLARTVGSTSTPRSRCTPRDALDLSDINSEPPRGSF
430 440 450 460 470 480
490
pF1KE0 PSFEPRNLLSLFEDTLDPT
:::::::::::::::::::
NP_004 PSFEPRNLLSLFEDTLDPT
490
>>XP_011521036 (OMIM: 602474) PREDICTED: membrane-associ (499 aa)
initn: 3504 init1: 3504 opt: 3504 Z-score: 1479.7 bits: 283.3 E(85289): 1.1e-75
Smith-Waterman score: 3504; 100.0% identity (100.0% similar) in 499 aa overlap (1-499:1-499)
10 20 30 40 50 60
pF1KE0 MLERPPALAMPMPTEGTPPPLSGTPIPVPAYFRHAEPGFSLKRPRGLSRSLPPPPPAKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLERPPALAMPMPTEGTPPPLSGTPIPVPAYFRHAEPGFSLKRPRGLSRSLPPPPPAKGS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 IPISRLFPPRTPGWHQLQPRRVSFRGEASETLQSPGYDPSRPESFFQQSFQRLSRLGHGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPISRLFPPRTPGWHQLQPRRVSFRGEASETLQSPGYDPSRPESFFQQSFQRLSRLGHGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 YGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVGSHEKVGQHPCCVRLEQAWEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVGSHEKVGQHPCCVRLEQAWEEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALAHLHSQGLVHLDVKPANIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALAHLHSQGLVHLDVKPANIF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LGPRGRCKLGDFGLLVELGTAGAGEVQEGDPRYMAPELLQGSYGTAADVFSLGLTILEVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGPRGRCKLGDFGLLVELGTAGAGEVQEGDPRYMAPELLQGSYGTAADVFSLGLTILEVA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 CNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLVMMLEPDPKLRATAEALLALPVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLVMMLEPDPKLRATAEALLALPVLR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 QPRAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASWLQPLGPPATPPGSPPCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPRAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASWLQPLGPPATPPGSPPCS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 LLLDSSLSSNWDDDSLGPSLSPEAVLARTVGSTSTPRSRCTPRDALDLSDINSEPPRGSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLLDSSLSSNWDDDSLGPSLSPEAVLARTVGSTSTPRSRCTPRDALDLSDINSEPPRGSF
430 440 450 460 470 480
490
pF1KE0 PSFEPRNLLSLFEDTLDPT
:::::::::::::::::::
XP_011 PSFEPRNLLSLFEDTLDPT
490
>>XP_011521037 (OMIM: 602474) PREDICTED: membrane-associ (490 aa)
initn: 3444 init1: 3444 opt: 3444 Z-score: 1454.9 bits: 278.7 E(85289): 2.7e-74
Smith-Waterman score: 3444; 100.0% identity (100.0% similar) in 490 aa overlap (10-499:1-490)
10 20 30 40 50 60
pF1KE0 MLERPPALAMPMPTEGTPPPLSGTPIPVPAYFRHAEPGFSLKRPRGLSRSLPPPPPAKGS
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPMPTEGTPPPLSGTPIPVPAYFRHAEPGFSLKRPRGLSRSLPPPPPAKGS
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 IPISRLFPPRTPGWHQLQPRRVSFRGEASETLQSPGYDPSRPESFFQQSFQRLSRLGHGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPISRLFPPRTPGWHQLQPRRVSFRGEASETLQSPGYDPSRPESFFQQSFQRLSRLGHGS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 YGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVGSHEKVGQHPCCVRLEQAWEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVGSHEKVGQHPCCVRLEQAWEEG
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 GILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALAHLHSQGLVHLDVKPANIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALAHLHSQGLVHLDVKPANIF
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE0 LGPRGRCKLGDFGLLVELGTAGAGEVQEGDPRYMAPELLQGSYGTAADVFSLGLTILEVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGPRGRCKLGDFGLLVELGTAGAGEVQEGDPRYMAPELLQGSYGTAADVFSLGLTILEVA
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE0 CNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLVMMLEPDPKLRATAEALLALPVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLVMMLEPDPKLRATAEALLALPVLR
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE0 QPRAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASWLQPLGPPATPPGSPPCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPRAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASWLQPLGPPATPPGSPPCS
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE0 LLLDSSLSSNWDDDSLGPSLSPEAVLARTVGSTSTPRSRCTPRDALDLSDINSEPPRGSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLLDSSLSSNWDDDSLGPSLSPEAVLARTVGSTSTPRSRCTPRDALDLSDINSEPPRGSF
420 430 440 450 460 470
490
pF1KE0 PSFEPRNLLSLFEDTLDPT
:::::::::::::::::::
XP_011 PSFEPRNLLSLFEDTLDPT
480 490
>>NP_001245380 (OMIM: 602474) membrane-associated tyrosi (490 aa)
initn: 3444 init1: 3444 opt: 3444 Z-score: 1454.9 bits: 278.7 E(85289): 2.7e-74
Smith-Waterman score: 3444; 100.0% identity (100.0% similar) in 490 aa overlap (10-499:1-490)
10 20 30 40 50 60
pF1KE0 MLERPPALAMPMPTEGTPPPLSGTPIPVPAYFRHAEPGFSLKRPRGLSRSLPPPPPAKGS
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPMPTEGTPPPLSGTPIPVPAYFRHAEPGFSLKRPRGLSRSLPPPPPAKGS
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 IPISRLFPPRTPGWHQLQPRRVSFRGEASETLQSPGYDPSRPESFFQQSFQRLSRLGHGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPISRLFPPRTPGWHQLQPRRVSFRGEASETLQSPGYDPSRPESFFQQSFQRLSRLGHGS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 YGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVGSHEKVGQHPCCVRLEQAWEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVGSHEKVGQHPCCVRLEQAWEEG
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 GILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALAHLHSQGLVHLDVKPANIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALAHLHSQGLVHLDVKPANIF
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE0 LGPRGRCKLGDFGLLVELGTAGAGEVQEGDPRYMAPELLQGSYGTAADVFSLGLTILEVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGPRGRCKLGDFGLLVELGTAGAGEVQEGDPRYMAPELLQGSYGTAADVFSLGLTILEVA
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE0 CNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLVMMLEPDPKLRATAEALLALPVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLVMMLEPDPKLRATAEALLALPVLR
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE0 QPRAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASWLQPLGPPATPPGSPPCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPRAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASWLQPLGPPATPPGSPPCS
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE0 LLLDSSLSSNWDDDSLGPSLSPEAVLARTVGSTSTPRSRCTPRDALDLSDINSEPPRGSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLLDSSLSSNWDDDSLGPSLSPEAVLARTVGSTSTPRSRCTPRDALDLSDINSEPPRGSF
420 430 440 450 460 470
490
pF1KE0 PSFEPRNLLSLFEDTLDPT
:::::::::::::::::::
NP_001 PSFEPRNLLSLFEDTLDPT
480 490
>>XP_011521038 (OMIM: 602474) PREDICTED: membrane-associ (490 aa)
initn: 3444 init1: 3444 opt: 3444 Z-score: 1454.9 bits: 278.7 E(85289): 2.7e-74
Smith-Waterman score: 3444; 100.0% identity (100.0% similar) in 490 aa overlap (10-499:1-490)
10 20 30 40 50 60
pF1KE0 MLERPPALAMPMPTEGTPPPLSGTPIPVPAYFRHAEPGFSLKRPRGLSRSLPPPPPAKGS
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPMPTEGTPPPLSGTPIPVPAYFRHAEPGFSLKRPRGLSRSLPPPPPAKGS
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 IPISRLFPPRTPGWHQLQPRRVSFRGEASETLQSPGYDPSRPESFFQQSFQRLSRLGHGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPISRLFPPRTPGWHQLQPRRVSFRGEASETLQSPGYDPSRPESFFQQSFQRLSRLGHGS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 YGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVGSHEKVGQHPCCVRLEQAWEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVGSHEKVGQHPCCVRLEQAWEEG
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 GILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALAHLHSQGLVHLDVKPANIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALAHLHSQGLVHLDVKPANIF
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE0 LGPRGRCKLGDFGLLVELGTAGAGEVQEGDPRYMAPELLQGSYGTAADVFSLGLTILEVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGPRGRCKLGDFGLLVELGTAGAGEVQEGDPRYMAPELLQGSYGTAADVFSLGLTILEVA
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE0 CNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLVMMLEPDPKLRATAEALLALPVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLVMMLEPDPKLRATAEALLALPVLR
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE0 QPRAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASWLQPLGPPATPPGSPPCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPRAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASWLQPLGPPATPPGSPPCS
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE0 LLLDSSLSSNWDDDSLGPSLSPEAVLARTVGSTSTPRSRCTPRDALDLSDINSEPPRGSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLLDSSLSSNWDDDSLGPSLSPEAVLARTVGSTSTPRSRCTPRDALDLSDINSEPPRGSF
420 430 440 450 460 470
490
pF1KE0 PSFEPRNLLSLFEDTLDPT
:::::::::::::::::::
XP_011 PSFEPRNLLSLFEDTLDPT
480 490
>>NP_872629 (OMIM: 602474) membrane-associated tyrosine- (480 aa)
initn: 3164 init1: 3107 opt: 3107 Z-score: 1315.5 bits: 252.9 E(85289): 1.5e-66
Smith-Waterman score: 3107; 99.3% identity (99.5% similar) in 442 aa overlap (1-442:1-442)
10 20 30 40 50 60
pF1KE0 MLERPPALAMPMPTEGTPPPLSGTPIPVPAYFRHAEPGFSLKRPRGLSRSLPPPPPAKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 MLERPPALAMPMPTEGTPPPLSGTPIPVPAYFRHAEPGFSLKRPRGLSRSLPPPPPAKGS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 IPISRLFPPRTPGWHQLQPRRVSFRGEASETLQSPGYDPSRPESFFQQSFQRLSRLGHGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 IPISRLFPPRTPGWHQLQPRRVSFRGEASETLQSPGYDPSRPESFFQQSFQRLSRLGHGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 YGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVGSHEKVGQHPCCVRLEQAWEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 YGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVGSHEKVGQHPCCVRLEQAWEEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALAHLHSQGLVHLDVKPANIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 GILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALAHLHSQGLVHLDVKPANIF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LGPRGRCKLGDFGLLVELGTAGAGEVQEGDPRYMAPELLQGSYGTAADVFSLGLTILEVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 LGPRGRCKLGDFGLLVELGTAGAGEVQEGDPRYMAPELLQGSYGTAADVFSLGLTILEVA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 CNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLVMMLEPDPKLRATAEALLALPVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 CNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLVMMLEPDPKLRATAEALLALPVLR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 QPRAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASWLQPLGPPATPPGSPPCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 QPRAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASWLQPLGPPATPPGSPPCS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 LLLDSSLSSNWDDDSLGPSLSPEAVLARTVGSTSTPRSRCTPRDALDLSDINSEPPRGSF
::::::::::::::::::. :
NP_872 LLLDSSLSSNWDDDSLGPGHPPCLACPPAGLHSPLRLSWPGLWGAPPPPGAGAHPGMPWT
430 440 450 460 470 480
>>NP_001245379 (OMIM: 602474) membrane-associated tyrosi (430 aa)
initn: 2974 init1: 2974 opt: 2974 Z-score: 1261.0 bits: 242.6 E(85289): 1.7e-63
Smith-Waterman score: 2974; 100.0% identity (100.0% similar) in 426 aa overlap (74-499:5-430)
50 60 70 80 90 100
pF1KE0 PRGLSRSLPPPPPAKGSIPISRLFPPRTPGWHQLQPRRVSFRGEASETLQSPGYDPSRPE
::::::::::::::::::::::::::::::
NP_001 MLERWHQLQPRRVSFRGEASETLQSPGYDPSRPE
10 20 30
110 120 130 140 150 160
pF1KE0 SFFQQSFQRLSRLGHGSYGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVGSHEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFFQQSFQRLSRLGHGSYGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVGSHEK
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE0 VGQHPCCVRLEQAWEEGGILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGQHPCCVRLEQAWEEGGILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALAH
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE0 LHSQGLVHLDVKPANIFLGPRGRCKLGDFGLLVELGTAGAGEVQEGDPRYMAPELLQGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHSQGLVHLDVKPANIFLGPRGRCKLGDFGLLVELGTAGAGEVQEGDPRYMAPELLQGSY
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE0 GTAADVFSLGLTILEVACNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLVMMLEPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTAADVFSLGLTILEVACNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLVMMLEPD
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE0 PKLRATAEALLALPVLRQPRAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKLRATAEALLALPVLRQPRAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASW
280 290 300 310 320 330
410 420 430 440 450 460
pF1KE0 LQPLGPPATPPGSPPCSLLLDSSLSSNWDDDSLGPSLSPEAVLARTVGSTSTPRSRCTPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQPLGPPATPPGSPPCSLLLDSSLSSNWDDDSLGPSLSPEAVLARTVGSTSTPRSRCTPR
340 350 360 370 380 390
470 480 490
pF1KE0 DALDLSDINSEPPRGSFPSFEPRNLLSLFEDTLDPT
::::::::::::::::::::::::::::::::::::
NP_001 DALDLSDINSEPPRGSFPSFEPRNLLSLFEDTLDPT
400 410 420 430
>>NP_003943 (OMIM: 608939) ribosomal protein S6 kinase b (482 aa)
initn: 282 init1: 189 opt: 400 Z-score: 195.0 bits: 45.5 E(85289): 0.0004
Smith-Waterman score: 400; 35.1% identity (59.2% similar) in 282 aa overlap (102-369:59-333)
80 90 100 110 120 130
pF1KE0 PGWHQLQPRRVSFRGEASETLQSPGYDPSRPESFFQQSFQRLSRLGHGSYGEVFKVRSKE
:: . . :. : ::.:.::.::.::. .
NP_003 CPLAELRAAGLEPVGHYEEVELTETSVNVGPERIGPHCFELLRVLGKGGYGKVFQVRKVQ
30 40 50 60 70 80
140 150 160 170 180
pF1KE0 D---GRLYAVK--RSMSPFRGPKDRARKLAEVGSHEKVGQHPCCVRLEQAWEEGGILYLQ
:..::.: :. . :. :: :. :: . :.: .:: :.: :.. :: :::
NP_003 GTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESV-KHPFIVELAYAFQTGGKLYLI
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE0 TE-LCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALAHLHSQGLVHLDVKPANIFLGPRG
: : : : : : : : .. . :: . :::.::::::... :.:: ::.:. .:
NP_003 LECLSGGELFTHLEREGIFLEDTACF-YLAEITLALGHLHSQGIIYRDLKPENIMLSSQG
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE0 RCKLGDFGLLVELGTAGA-GEVQEGDPRYMAPELL-QGSYGTAADVFSLGLTILEVACNM
. :: :::: : :: .. : .:::::.: ..... :.: .::: . .. .
NP_003 HIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGS
210 220 230 240 250 260
310 320 330 340 350
pF1KE0 ELPHGGEGWQQ----LRQGYL--PPEFTAGLSSELRSVLVMMLEPDPKLRATAEALLALP
: .:. .. . .: : :: :. . :... .:. .:. : . :
NP_003 P-PFTAENRKKTMDKIIRGKLALPPY----LTPDARDLVKKFLKRNPSQRIGGGPGDAAD
270 280 290 300 310 320
360 370 380 390 400 410
pF1KE0 VLRQPRAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASWLQPLGPPATPPGSP
: :.: . :
NP_003 VQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFDTRFTRQTPVDSPDDTALSESAN
330 340 350 360 370 380
>>XP_011530307 (OMIM: 263520,604588) PREDICTED: serine/t (715 aa)
initn: 281 init1: 127 opt: 387 Z-score: 187.8 bits: 44.8 E(85289): 0.001
Smith-Waterman score: 387; 29.4% identity (65.9% similar) in 255 aa overlap (108-354:2-253)
80 90 100 110 120 130
pF1KE0 QPRRVSFRGEASETLQSPGYDPSRPESFFQQSFQRLSRLGHGSYGEVFKVRSKEDGRLYA
... ::...:.::.:... :.: :::: :.
XP_011 MEKYVRLQKIGEGSFGKAILVKSTEDGRQYV
10 20 30
140 150 160 170 180 190
pF1KE0 VKRSMSPFRGPKDRARKLAEVGSHEKVGQHPCCVRLEQAWEEGGILYLQTELC-GPSLQQ
.:. . :.: .. ::. .. .:: :. ....::.: ::. . : : .: .
XP_011 IKEINISRMSSKEREESRREVAVLANM-KHPNIVQYRESFEENGSLYIVMDYCEGGDLFK
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE0 HCEAW-GASLPEAQVWGYLRDTLLALAHLHSQGLVHLDVKPANIFLGPRGRCKLGDFGLL
. .: :. . : :. .. . ::: :.:.. ..: :.: :::: : .:::::.
XP_011 RINAQKGVLFQEDQILDWFVQICLALKHVHDRKILHRDIKSQNIFLTKDGTVQLGDFGIA
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE0 VELG-TAGAGEVQEGDPRYMAPELLQGS-YGTAADVFSLGLTILEVACNMELPHGGEGWQ
:. :. ... : : :..::. ... :.. .:...:: .. :. :... . . .
XP_011 RVLNSTVELARTCIGTPYYLSPEICENKPYNNKSDIWALGCVLYEL-CTLKHAFEAGSMK
160 170 180 190 200
320 330 340 350 360
pF1KE0 QLR----QGYLPPEFTAGLSSELRSVLVMMLEPDPKLRATAEALLALPVLRQPRAWGVLW
.: .: .:: . : .:::.. .... .:. : .....:
XP_011 NLVLKIISGSFPP-VSLHYSYDLRSLVSQLFKRNPRDRPSVNSILEKGFIAKRIEKFLSP
210 220 230 240 250 260
370 380 390 400 410 420
pF1KE0 CMAAEALSRGWALWQALLALLCWLWHGLAHPASWLQPLGPPATPPGSPPCSLLLDSSLSS
XP_011 QLIAEEFCLKTFSKFGSQPIPAKRPASGQNSISVMPAQKITKPAAKYGIPLAYKKYGDKK
270 280 290 300 310 320
>>NP_004064 (OMIM: 602913) serine/threonine-protein kina (646 aa)
initn: 338 init1: 210 opt: 385 Z-score: 187.4 bits: 44.6 E(85289): 0.0011
Smith-Waterman score: 394; 30.3% identity (55.6% similar) in 333 aa overlap (36-354:2-309)
10 20 30 40 50 60
pF1KE0 PALAMPMPTEGTPPPLSGTPIPVPAYFRHAEPGFSLKRPRGLSRSLPPPPPAKGSIPISR
::. .. :: ..:. : : : :
NP_004 MEPAAGFLSPRPFQRAAAAPAPPAGPGP---
10 20
70 80 90 100 110 120
pF1KE0 LFPPRTPGWHQLQPRRVSFRGEASETLQS-PGYDPSR----PESFFQQSFQRLSRLGHGS
:: ..:: : : . : ::.: :.: ... . ::.:.
NP_004 --PPS------------ALRGPELEMLAGLPTSDPGRLITDPRS--GRTYLKGRLLGKGG
30 40 50 60 70
130 140 150 160 170
pF1KE0 YGEVFKVRSKEDGRLYAVKR-SMSPFRGPKDRARKLAEVGSHEKVGQHPCCVRLEQAWEE
... ... . : : :::: .: :..: . : :. :. . :: ::. . .:.
NP_004 FARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELHRDL-QHRHIVRFSHHFED
80 90 100 110 120 130
180 190 200 210 220 230
pF1KE0 GGILYLQTELCGPSLQQHCEAWGA--SLPEAQVWGYLRDTLLALAHLHSQGLVHLDVKPA
. .:. :::. . : : : .: : .: :::. : .: .::..:..: :.: .
NP_004 ADNIYIFLELCSRKSLAH--IWKARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLG
140 150 160 170 180
240 250 260 270 280 290
pF1KE0 NIFLGPRGRCKLGDFGLLVEL-GTAGAGEVQEGDPRYMAPE-LLQGSYGTAADVFSLGLT
:.:. . :.::::: ..: .. : : :.::: ::. ..: :::.::: .
NP_004 NFFITENMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQGHGPEADVWSLGCV
190 200 210 220 230 240
300 310 320 330 340 350
pF1KE0 ILEVACN---MELPHGGEGWQQLRQ-GYLPPEFTAGLSSELRSVLVMMLEPDPKLRATAE
. . :. .: : .. ..: : : :.:: :..:. .:. .:. : . .
NP_004 MYTLLCGSPPFETADLKETYRCIKQVHYTLP---ASLSLPARQLLAAILRASPRDRPSID
250 260 270 280 290 300
360 370 380 390 400 410
pF1KE0 ALLALPVLRQPRAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASWLQPLGPPA
.:
NP_004 QILRHDFFTKGYTPDRLPISSCVTVPDLTPPNPARSLFAKVTKSLFGRKKKSKNHAQERD
310 320 330 340 350 360
499 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 04:43:11 2016 done: Sat Nov 5 04:43:12 2016
Total Scan time: 12.650 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]