FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0964, 508 aa 1>>>pF1KE0964 508 - 508 aa - 508 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1417+/-0.00118; mu= 9.6907+/- 0.069 mean_var=161.4507+/-36.166, 0's: 0 Z-trim(105.8): 82 B-trim: 0 in 0/50 Lambda= 0.100938 statistics sampled from 8567 (8632) to 8567 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.635), E-opt: 0.2 (0.265), width: 16 Scan time: 3.090 The best scores are: opt bits E(32554) CCDS1859.1 VRK2 gene_id:7444|Hs108|chr2 ( 508) 3432 512.6 4.1e-145 CCDS46292.1 VRK2 gene_id:7444|Hs108|chr2 ( 485) 3265 488.3 8.3e-138 CCDS46291.1 VRK2 gene_id:7444|Hs108|chr2 ( 396) 2681 403.1 2.9e-112 CCDS9947.1 VRK1 gene_id:7443|Hs108|chr14 ( 396) 1151 180.3 3.4e-45 CCDS33076.1 VRK3 gene_id:51231|Hs108|chr19 ( 424) 676 111.2 2.3e-24 CCDS12791.1 VRK3 gene_id:51231|Hs108|chr19 ( 474) 676 111.2 2.5e-24 CCDS77334.1 VRK3 gene_id:51231|Hs108|chr19 ( 412) 634 105.1 1.6e-22 CCDS11806.1 CSNK1D gene_id:1453|Hs108|chr17 ( 409) 372 66.9 4.8e-11 CCDS11805.1 CSNK1D gene_id:1453|Hs108|chr17 ( 415) 372 66.9 4.9e-11 >>CCDS1859.1 VRK2 gene_id:7444|Hs108|chr2 (508 aa) initn: 3432 init1: 3432 opt: 3432 Z-score: 2718.7 bits: 512.6 E(32554): 4.1e-145 Smith-Waterman score: 3432; 99.8% identity (100.0% similar) in 508 aa overlap (1-508:1-508) 10 20 30 40 50 60 pF1KE0 MPPKRNEKYKLPIPFPEGKVLDDMEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 MPPKRNEKYKLPIPFPEGKVLDDMEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KVEYQENGPLFSELKFYQRVAKKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 KVEYQENGPLFSELKFYQRVAKKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 MERLGIDLQKISGQNGTFKKSTVLQLGIRMLDVLEYIHENEYVHGDVKAANLLLGYKNPD ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: CCDS18 MERLGIDLQKISGQNGTFKKSTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGYKNPD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 QVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 QVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 LRWLCGKLPWEQNLKDPVAVQTAKTNLLDELPQSVLKWAPSGSSCCEIAQFLVCAHSLAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 LRWLCGKLPWEQNLKDPVAVQTAKTNLLDELPQSVLKWAPSGSSCCEIAQFLVCAHSLAY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 DEKPNYQALKKILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAATKQVNKAHNRLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 DEKPNYQALKKILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAATKQVNKAHNRLI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 EKKVHSERSAESCATWKVQKEEKLIGLMNNEAAQESTRRRQKYQESQEPLNEVNSFPQKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 EKKVHSERSAESCATWKVQKEEKLIGLMNNEAAQESTRRRQKYQESQEPLNEVNSFPQKI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 SYTQFPNSFYEPHQDFTSPDIFKKSRSPSWYKYTSTVSTGITDLESSTGLWPTISQFTLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 SYTQFPNSFYEPHQDFTSPDIFKKSRSPSWYKYTSTVSTGITDLESSTGLWPTISQFTLS 430 440 450 460 470 480 490 500 pF1KE0 EETNADVYYYRIIIPVLLMLVFLALFFL :::::::::::::::::::::::::::: CCDS18 EETNADVYYYRIIIPVLLMLVFLALFFL 490 500 >>CCDS46292.1 VRK2 gene_id:7444|Hs108|chr2 (485 aa) initn: 3265 init1: 3265 opt: 3265 Z-score: 2587.6 bits: 488.3 E(32554): 8.3e-138 Smith-Waterman score: 3265; 99.8% identity (100.0% similar) in 485 aa overlap (24-508:1-485) 10 20 30 40 50 60 pF1KE0 MPPKRNEKYKLPIPFPEGKVLDDMEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVV ::::::::::::::::::::::::::::::::::::: CCDS46 MEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVV 10 20 30 70 80 90 100 110 120 pF1KE0 KVEYQENGPLFSELKFYQRVAKKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 KVEYQENGPLFSELKFYQRVAKKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMV 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 MERLGIDLQKISGQNGTFKKSTVLQLGIRMLDVLEYIHENEYVHGDVKAANLLLGYKNPD ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: CCDS46 MERLGIDLQKISGQNGTFKKSTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGYKNPD 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE0 QVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 QVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCM 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE0 LRWLCGKLPWEQNLKDPVAVQTAKTNLLDELPQSVLKWAPSGSSCCEIAQFLVCAHSLAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LRWLCGKLPWEQNLKDPVAVQTAKTNLLDELPQSVLKWAPSGSSCCEIAQFLVCAHSLAY 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE0 DEKPNYQALKKILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAATKQVNKAHNRLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 DEKPNYQALKKILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAATKQVNKAHNRLI 280 290 300 310 320 330 370 380 390 400 410 420 pF1KE0 EKKVHSERSAESCATWKVQKEEKLIGLMNNEAAQESTRRRQKYQESQEPLNEVNSFPQKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 EKKVHSERSAESCATWKVQKEEKLIGLMNNEAAQESTRRRQKYQESQEPLNEVNSFPQKI 340 350 360 370 380 390 430 440 450 460 470 480 pF1KE0 SYTQFPNSFYEPHQDFTSPDIFKKSRSPSWYKYTSTVSTGITDLESSTGLWPTISQFTLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SYTQFPNSFYEPHQDFTSPDIFKKSRSPSWYKYTSTVSTGITDLESSTGLWPTISQFTLS 400 410 420 430 440 450 490 500 pF1KE0 EETNADVYYYRIIIPVLLMLVFLALFFL :::::::::::::::::::::::::::: CCDS46 EETNADVYYYRIIIPVLLMLVFLALFFL 460 470 480 >>CCDS46291.1 VRK2 gene_id:7444|Hs108|chr2 (396 aa) initn: 2681 init1: 2681 opt: 2681 Z-score: 2129.1 bits: 403.1 E(32554): 2.9e-112 Smith-Waterman score: 2681; 99.7% identity (100.0% similar) in 394 aa overlap (1-394:1-394) 10 20 30 40 50 60 pF1KE0 MPPKRNEKYKLPIPFPEGKVLDDMEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MPPKRNEKYKLPIPFPEGKVLDDMEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KVEYQENGPLFSELKFYQRVAKKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 KVEYQENGPLFSELKFYQRVAKKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 MERLGIDLQKISGQNGTFKKSTVLQLGIRMLDVLEYIHENEYVHGDVKAANLLLGYKNPD ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: CCDS46 MERLGIDLQKISGQNGTFKKSTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGYKNPD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 QVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 QVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 LRWLCGKLPWEQNLKDPVAVQTAKTNLLDELPQSVLKWAPSGSSCCEIAQFLVCAHSLAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LRWLCGKLPWEQNLKDPVAVQTAKTNLLDELPQSVLKWAPSGSSCCEIAQFLVCAHSLAY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 DEKPNYQALKKILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAATKQVNKAHNRLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 DEKPNYQALKKILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAATKQVNKAHNRLI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 EKKVHSERSAESCATWKVQKEEKLIGLMNNEAAQESTRRRQKYQESQEPLNEVNSFPQKI :::::::::::::::::::::::::::::::::: CCDS46 EKKVHSERSAESCATWKVQKEEKLIGLMNNEAAQFR 370 380 390 430 440 450 460 470 480 pF1KE0 SYTQFPNSFYEPHQDFTSPDIFKKSRSPSWYKYTSTVSTGITDLESSTGLWPTISQFTLS >>CCDS9947.1 VRK1 gene_id:7443|Hs108|chr14 (396 aa) initn: 1182 init1: 728 opt: 1151 Z-score: 925.0 bits: 180.3 E(32554): 3.4e-45 Smith-Waterman score: 1162; 47.0% identity (71.4% similar) in 406 aa overlap (4-405:12-396) 10 20 30 40 50 pF1KE0 MPPKRNEKYKLPIPFPEGKVLDDMEGNQWVLGKKIGSGGFGLIYLAFPTNKP . . : .: : :... :: ..: .: ::.:::: :::: :. CCDS99 MPRVKAAQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLA-DMNSS 10 20 30 40 50 60 70 80 90 100 pF1KE0 EK---DARHVVKVEYQENGPLFSELKFYQRVAKKDCIKKWIERKQLDYLGIPLFYGSGLT :. :: ::::: ..:::::.:::::::.:: . :.:::. ..: :::.: ..:::: CCDS99 ESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLH 60 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 EFKGRSYRFMVMERLGIDLQKISGQNGT-FKKSTVLQLGIRMLDVLEYIHENEYVHGDVK . .:.:::::.:.:.: ::::: :. :...:::::..:.::.::::::.::::::.: CCDS99 DKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIK 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 AANLLLGYKNPDQVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALS :.::::.:::::::::.::::.:::::.: ::.:.:.:.. :.:::::::.:::.::: : CCDS99 ASNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPS 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 RRSDVEILGYCMLRWLCGKLPWEQNLKDPVAVQTAKTNLLDELPQSVLKWAPSGSSCCEI ::.:.:::::::..:: :.::::.::::: :. .: ... . . : : .. :: CCDS99 RRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEI 240 250 260 270 280 290 290 300 310 320 330 340 pF1KE0 AQFLVCAHSLAYDEKPNYQALKKILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAA :... .. : : ::: :. :. :: .: : . :. :.. CCDS99 AKYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSV---------VENGGLK 300 310 320 330 340 350 350 360 370 380 390 400 pF1KE0 TKQVNKAHNRLIEKKVHSERSAESCATWKVQKEEKLIGLMNNEAAQESTRRRQKYQESQE .: ..: ... ::.. .: ..:. . :. . : :: : .: :.. :. CCDS99 AKTITKKRKKEIEES--KEPGVED-TEWSNTQTE--------EAIQTRSRTRKRVQK 360 370 380 390 410 420 430 440 450 460 pF1KE0 PLNEVNSFPQKISYTQFPNSFYEPHQDFTSPDIFKKSRSPSWYKYTSTVSTGITDLESST >>CCDS33076.1 VRK3 gene_id:51231|Hs108|chr19 (424 aa) initn: 667 init1: 483 opt: 676 Z-score: 550.7 bits: 111.2 E(32554): 2.3e-24 Smith-Waterman score: 677; 36.8% identity (63.2% similar) in 334 aa overlap (15-322:102-424) 10 20 30 40 pF1KE0 MPPKRNEKYKLPIPFPEGKVLDDMEGNQWVLGKKIGSGGFGLIY .: : :: : : :: : . . :..: CCDS33 SPQKTSCSPQKTRQSPQTLKRSRVTTSLEALPTGTVLTDKSGRQWKLKSFQTRDNQGILY 80 90 100 110 120 130 50 60 70 80 90 pF1KE0 LAFPTNK------PEKDARHVVKVEYQENGPLFSELKFYQRVAKKDCIKKWIERKQLDYL : ::. :.:. . .:.. .. : ::.: .:.::.:: ..:: . . : CCDS33 EAAPTSTLTCDSGPQKQ-KFSLKLDAKD-GRLFNEQNFFQRAAKPLQVNKWKKLYSTPLL 140 150 160 170 180 100 110 120 130 140 150 pF1KE0 GIPLFYGSGLTEFKGRSYRFMVMERLGIDLQK---ISGQNGTFKKSTVLQLGIRMLDVLE .:: .: :. . : :::.:. :: .::. .: .. .... .:::.. :.::.:: CCDS33 AIPTCMGFGVHQDK---YRFLVLPSLGRSLQSALDVSPKH-VLSERSVLQVACRLLDALE 190 200 210 220 230 240 160 170 180 190 200 210 pF1KE0 YIHENEYVHGDVKAANLLLGYKNPDQVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIE ..::::::::.: : :... .. .:: :: ::...::::.:.: : :. :. :.: .: CCDS33 FLHENEYVHGNVTAENIFVDPEDQSQVTLAGYGFAFRYCPSGKHVAYVEGSRSPHEGDLE 250 260 270 280 290 300 220 230 240 250 260 270 pF1KE0 FTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDPVAVQTAKTNLLDELPQSV : :.: ::: . :::::.. ::::::.:: : ::: . : . .. : ...:. : CCDS33 FISMDLHKGCGPSRRSDLQSLGYCMLKWLYGFLPWTNCLPNTEDIMKQKQKFVDK-PGPF 310 320 330 340 350 360 280 290 300 310 pF1KE0 L----KWA-PSGSSCCEIAQFLVCAHSLAYDEKPNYQALKKIL------------NPHGI . .: :: . . ..: . .:.:.::: : :.. : .: :. CCDS33 VGPCGHWIRPSET----LQKYLKVVMALTYEEKPPYAMLRNNLEALLQDLRVSPYDPIGL 370 380 390 400 410 420 320 330 340 350 360 370 pF1KE0 PLGPLDFSTKGQSINVHTPNSQKVDSQKAATKQVNKAHNRLIEKKVHSERSAESCATWKV :. : CCDS33 PMVP >>CCDS12791.1 VRK3 gene_id:51231|Hs108|chr19 (474 aa) initn: 667 init1: 483 opt: 676 Z-score: 550.1 bits: 111.2 E(32554): 2.5e-24 Smith-Waterman score: 677; 36.8% identity (63.2% similar) in 334 aa overlap (15-322:152-474) 10 20 30 40 pF1KE0 MPPKRNEKYKLPIPFPEGKVLDDMEGNQWVLGKKIGSGGFGLIY .: : :: : : :: : . . :..: CCDS12 SPQKTSCSPQKTRQSPQTLKRSRVTTSLEALPTGTVLTDKSGRQWKLKSFQTRDNQGILY 130 140 150 160 170 180 50 60 70 80 90 pF1KE0 LAFPTNK------PEKDARHVVKVEYQENGPLFSELKFYQRVAKKDCIKKWIERKQLDYL : ::. :.:. . .:.. .. : ::.: .:.::.:: ..:: . . : CCDS12 EAAPTSTLTCDSGPQKQ-KFSLKLDAKD-GRLFNEQNFFQRAAKPLQVNKWKKLYSTPLL 190 200 210 220 230 100 110 120 130 140 150 pF1KE0 GIPLFYGSGLTEFKGRSYRFMVMERLGIDLQK---ISGQNGTFKKSTVLQLGIRMLDVLE .:: .: :. . : :::.:. :: .::. .: .. .... .:::.. :.::.:: CCDS12 AIPTCMGFGVHQDK---YRFLVLPSLGRSLQSALDVSPKH-VLSERSVLQVACRLLDALE 240 250 260 270 280 290 160 170 180 190 200 210 pF1KE0 YIHENEYVHGDVKAANLLLGYKNPDQVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIE ..::::::::.: : :... .. .:: :: ::...::::.:.: : :. :. :.: .: CCDS12 FLHENEYVHGNVTAENIFVDPEDQSQVTLAGYGFAFRYCPSGKHVAYVEGSRSPHEGDLE 300 310 320 330 340 350 220 230 240 250 260 270 pF1KE0 FTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDPVAVQTAKTNLLDELPQSV : :.: ::: . :::::.. ::::::.:: : ::: . : . .. : ...:. : CCDS12 FISMDLHKGCGPSRRSDLQSLGYCMLKWLYGFLPWTNCLPNTEDIMKQKQKFVDK-PGPF 360 370 380 390 400 410 280 290 300 310 pF1KE0 L----KWA-PSGSSCCEIAQFLVCAHSLAYDEKPNYQALKKIL------------NPHGI . .: :: . . ..: . .:.:.::: : :.. : .: :. CCDS12 VGPCGHWIRPSET----LQKYLKVVMALTYEEKPPYAMLRNNLEALLQDLRVSPYDPIGL 420 430 440 450 460 470 320 330 340 350 360 370 pF1KE0 PLGPLDFSTKGQSINVHTPNSQKVDSQKAATKQVNKAHNRLIEKKVHSERSAESCATWKV :. : CCDS12 PMVP >>CCDS77334.1 VRK3 gene_id:51231|Hs108|chr19 (412 aa) initn: 652 init1: 444 opt: 634 Z-score: 517.8 bits: 105.1 E(32554): 1.6e-22 Smith-Waterman score: 634; 40.5% identity (67.2% similar) in 262 aa overlap (15-267:152-407) 10 20 30 40 pF1KE0 MPPKRNEKYKLPIPFPEGKVLDDMEGNQWVLGKKIGSGGFGLIY .: : :: : : :: : . . :..: CCDS77 SPQKTSCSPQKTRQSPQTLKRSRVTTSLEALPTGTVLTDKSGRQWKLKSFQTRDNQGILY 130 140 150 160 170 180 50 60 70 80 90 pF1KE0 LAFPTNK------PEKDARHVVKVEYQENGPLFSELKFYQRVAKKDCIKKWIERKQLDYL : ::. :.:. . .:.. .. : ::.: .:.::.:: ..:: . . : CCDS77 EAAPTSTLTCDSGPQKQ-KFSLKLDAKD-GRLFNEQNFFQRAAKPLQVNKWKKLYSTPLL 190 200 210 220 230 100 110 120 130 140 150 pF1KE0 GIPLFYGSGLTEFKGRSYRFMVMERLGIDLQK---ISGQNGTFKKSTVLQLGIRMLDVLE .:: .: :. . : :::.:. :: .::. .: .. .... .:::.. :.::.:: CCDS77 AIPTCMGFGVHQDK---YRFLVLPSLGRSLQSALDVSPKH-VLSERSVLQVACRLLDALE 240 250 260 270 280 290 160 170 180 190 200 210 pF1KE0 YIHENEYVHGDVKAANLLLGYKNPDQVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIE ..::::::::.: : :... .. .:: :: ::...::::.:.: : :. :. :.: .: CCDS77 FLHENEYVHGNVTAENIFVDPEDQSQVTLAGYGFAFRYCPSGKHVAYVEGSRSPHEGDLE 300 310 320 330 340 350 220 230 240 250 260 270 pF1KE0 FTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDPVAVQTAKTNLLDELPQSV : :.: ::: . :::::.. ::::::.:: : ::: . : . .. : .: CCDS77 FISMDLHKGCGPSRRSDLQSLGYCMLKWLYGFLPWTNCLPNTEDIMKQKQKLPWDSF 360 370 380 390 400 410 280 290 300 310 320 330 pF1KE0 LKWAPSGSSCCEIAQFLVCAHSLAYDEKPNYQALKKILNPHGIPLGPLDFSTKGQSINVH >>CCDS11806.1 CSNK1D gene_id:1453|Hs108|chr17 (409 aa) initn: 378 init1: 181 opt: 372 Z-score: 311.7 bits: 66.9 E(32554): 4.8e-11 Smith-Waterman score: 426; 32.8% identity (57.4% similar) in 357 aa overlap (26-370:6-322) 10 20 30 40 50 60 pF1KE0 MPPKRNEKYKLPIPFPEGKVLDDMEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVV ::.. ::.:::::.:: :::. :. : . CCDS11 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVA---I 10 20 30 70 80 90 100 110 pF1KE0 KVE-YQENGP-LFSELKFYQRVAKKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRF :.: . . : : : :.:. . .::: . : .: .: CCDS11 KLECVKTKHPQLHIESKIYKMMQGG--------------VGIPTIRWCGA---EG-DYNV 40 50 60 70 120 130 140 150 160 170 pF1KE0 MVMERLGIDLQKISG-QNGTFKKSTVLQLGIRMLDVLEYIHENEYVHGDVKAANLLLGY- :::: :: .:. . . . :. .::: :. .:.. .:::: ....: ::: :.:.: CCDS11 MVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLG 80 90 100 110 120 130 180 190 200 210 220 230 pF1KE0 KNPDQVYLADYGLSYRYCPNGNHKQ--YQENPRKGHNGTIEFTSLDAHKGVALSRRSDVE :. . ::. :.::. .: .:.. :.:: :. .:: ...:...: :. :::.:.: CCDS11 KKGNLVYIIDFGLAKKYRDARTHQHIPYREN--KNLTGTARYASINTHLGIEQSRRDDLE 140 150 160 170 180 190 240 250 260 270 280 pF1KE0 ILGYCMLRWLCGKLPWEQNLKDPVAVQTAKTNLLDE----LPQSVL-KWAPSGSSCCEIA ::: .. . :.::: :.:: .:.. : . ..: : :: : :: :.: CCDS11 SLGYVLMYFNLGSLPW-QGLK--AATKRQKYERISEKKMSTPIEVLCKGYPS-----EFA 200 210 220 230 240 290 300 310 320 330 340 pF1KE0 QFLVCAHSLAYDEKPNYQALKKILNPHGIPLGPLDFSTKGQSIN-VHTPNSQKVDSQKAA .: .:: .:.::.:. :.... : .: : . : : : ...:: CCDS11 TYLNFCRSLRFDDKPDYSYLRQLFRNL--------FHRQGFSYDYVFDWNMLKFGASRAA 250 260 270 280 290 300 350 360 370 380 390 400 pF1KE0 TKQVNKAHNRLIEKKVHSERSAESCATWKVQKEEKLIGLMNNEAAQESTRRRQKYQESQE . ..: :. ::. : CCDS11 DDAERERRDRE-ERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPV 310 320 330 340 350 360 >>CCDS11805.1 CSNK1D gene_id:1453|Hs108|chr17 (415 aa) initn: 378 init1: 181 opt: 372 Z-score: 311.6 bits: 66.9 E(32554): 4.9e-11 Smith-Waterman score: 426; 32.8% identity (57.4% similar) in 357 aa overlap (26-370:6-322) 10 20 30 40 50 60 pF1KE0 MPPKRNEKYKLPIPFPEGKVLDDMEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVV ::.. ::.:::::.:: :::. :. : . CCDS11 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVA---I 10 20 30 70 80 90 100 110 pF1KE0 KVE-YQENGP-LFSELKFYQRVAKKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRF :.: . . : : : :.:. . .::: . : .: .: CCDS11 KLECVKTKHPQLHIESKIYKMMQGG--------------VGIPTIRWCGA---EG-DYNV 40 50 60 70 120 130 140 150 160 170 pF1KE0 MVMERLGIDLQKISG-QNGTFKKSTVLQLGIRMLDVLEYIHENEYVHGDVKAANLLLGY- :::: :: .:. . . . :. .::: :. .:.. .:::: ....: ::: :.:.: CCDS11 MVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLG 80 90 100 110 120 130 180 190 200 210 220 230 pF1KE0 KNPDQVYLADYGLSYRYCPNGNHKQ--YQENPRKGHNGTIEFTSLDAHKGVALSRRSDVE :. . ::. :.::. .: .:.. :.:: :. .:: ...:...: :. :::.:.: CCDS11 KKGNLVYIIDFGLAKKYRDARTHQHIPYREN--KNLTGTARYASINTHLGIEQSRRDDLE 140 150 160 170 180 190 240 250 260 270 280 pF1KE0 ILGYCMLRWLCGKLPWEQNLKDPVAVQTAKTNLLDE----LPQSVL-KWAPSGSSCCEIA ::: .. . :.::: :.:: .:.. : . ..: : :: : :: :.: CCDS11 SLGYVLMYFNLGSLPW-QGLK--AATKRQKYERISEKKMSTPIEVLCKGYPS-----EFA 200 210 220 230 240 290 300 310 320 330 340 pF1KE0 QFLVCAHSLAYDEKPNYQALKKILNPHGIPLGPLDFSTKGQSIN-VHTPNSQKVDSQKAA .: .:: .:.::.:. :.... : .: : . : : : ...:: CCDS11 TYLNFCRSLRFDDKPDYSYLRQLFRNL--------FHRQGFSYDYVFDWNMLKFGASRAA 250 260 270 280 290 300 350 360 370 380 390 400 pF1KE0 TKQVNKAHNRLIEKKVHSERSAESCATWKVQKEEKLIGLMNNEAAQESTRRRQKYQESQE . ..: :. ::. : CCDS11 DDAERERRDRE-ERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPV 310 320 330 340 350 360 508 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 08:07:32 2016 done: Sat Nov 5 08:07:32 2016 Total Scan time: 3.090 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]