FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0977, 571 aa 1>>>pF1KE0977 571 - 571 aa - 571 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.1218+/-0.000943; mu= 6.0002+/- 0.055 mean_var=258.5495+/-56.364, 0's: 0 Z-trim(112.3): 622 B-trim: 0 in 0/52 Lambda= 0.079763 statistics sampled from 12339 (13089) to 12339 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.749), E-opt: 0.2 (0.402), width: 16 Scan time: 3.950 The best scores are: opt bits E(32554) CCDS41323.1 TESK2 gene_id:10420|Hs108|chr1 ( 571) 3899 462.5 6.2e-130 CCDS6580.1 TESK1 gene_id:7016|Hs108|chr9 ( 626) 1336 167.6 4e-41 >>CCDS41323.1 TESK2 gene_id:10420|Hs108|chr1 (571 aa) initn: 3899 init1: 3899 opt: 3899 Z-score: 2446.1 bits: 462.5 E(32554): 6.2e-130 Smith-Waterman score: 3899; 100.0% identity (100.0% similar) in 571 aa overlap (1-571:1-571) 10 20 30 40 50 60 pF1KE0 MDRSKRNSIAGFPPRVERLEEFEGGGGGEGNVSQVGRVWPSSYRALISAFSRLTRLDDFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 MDRSKRNSIAGFPPRVERLEEFEGGGGGEGNVSQVGRVWPSSYRALISAFSRLTRLDDFT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 CEKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNRLSHPNILRFMGVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 CEKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNRLSHPNILRFMGVC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VHQGQLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 VHQGQLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 NCLIKRDENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDEPYNEKADVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 NCLIKRDENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDEPYNEKADVF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 SYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCNMDPKLRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCNMDPKLRP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 SFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPHKSPCPRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPHKSPCPRR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 TIWLSRSQSDIFSRKPPRTVSVLDPYYRPRDGAARTPKVNPFSARQDLMGGKIKFFDLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 TIWLSRSQSDIFSRKPPRTVSVLDPYYRPRDGAARTPKVNPFSARQDLMGGKIKFFDLPS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 KSVISLVFDLDAPGPGTMPLADWQEPLAPPIRRWRSLPGSPEFLHQEACPFVGREESLSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 KSVISLVFDLDAPGPGTMPLADWQEPLAPPIRRWRSLPGSPEFLHQEACPFVGREESLSD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 GPPPRLSSLKYRVKEIPPFRASALPAAQAHEAMDCSILQEENGFGSRPQGTSPCPAGASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 GPPPRLSSLKYRVKEIPPFRASALPAAQAHEAMDCSILQEENGFGSRPQGTSPCPAGASE 490 500 510 520 530 540 550 560 570 pF1KE0 EMEVEERPAGSTPATFSTSGIGLQTQGKQDG ::::::::::::::::::::::::::::::: CCDS41 EMEVEERPAGSTPATFSTSGIGLQTQGKQDG 550 560 570 >>CCDS6580.1 TESK1 gene_id:7016|Hs108|chr9 (626 aa) initn: 1189 init1: 752 opt: 1336 Z-score: 851.7 bits: 167.6 E(32554): 4e-41 Smith-Waterman score: 1547; 54.2% identity (68.8% similar) in 509 aa overlap (25-516:25-500) 10 20 30 40 50 60 pF1KE0 MDRSKRNSIAGFPPRVERLEEFEGGGGGEGNVSQVGRVWPSSYRALISAFSRLTRLDDFT : :: :. :: ::::::: :: : :.:.::: CCDS65 MAGERPPLRGPGPGPGEVPGEGPPGPGGTGGGPGRGR--PSSYRALRSAVSSLARVDDFH 10 20 30 40 50 70 80 90 100 110 pF1KE0 C-EKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNRLSHPNILRFMGV : ::::.::::::.::::: :::::.:::: : :::.: :.:::::::: :::::::::: CCDS65 CAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRGNTLREVQLMNRLRHPNILRFMGV 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 CVHQGQLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTS :::::::::::::.:.:.:::::.: : : ::..:: ::: :: ::: ::.::::::: CCDS65 CVHQGQLHALTEYMNGGTLEQLLSSPEPLSWPVRLHLALDIARGLRYLHSKGVFHRDLTS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 KNCLIKRDENGYSAVVADFGLAEKIPDVSMGSEK--LAVVGSPFWMAPEVLRDEPYNEKA ::::..:.. :..:::.::::::::: :..: :::::::.:::::::: : :.::: CCDS65 KNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGELYDEKA 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 DVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGD-CPPDFLQLTFNCCNMDP :::..::.:::.:::. ::::::::::.:::: ::. .::: :: :: :...:::..: CCDS65 DVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVGDDCPLPFLLLAIHCCNLEP 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 KLRPSFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPHKSP . : :.:: . :: :: .: : : .: : . : .. . .:. : CCDS65 STRAPFTEITQHLEWILEQLPEPA--------PLTRTALTHNQGSVARGGPSATLPR--P 300 310 320 330 340 360 370 380 390 400 410 pF1KE0 CPRRTIWLSRSQSDIFSRKPPRTVSVLDPYYRPRDGAARTPKVNPFSARQDLMGGKIKFF :: ::::.::.: :: .: : : : .::::: :.:: :::::.. CCDS65 DPR----LSRSRSDLFL--PP------SPESPPNWGDNLT-RVNPFSLREDLRGGKIKLL 350 360 370 380 390 420 430 440 450 460 470 pF1KE0 DLPSKSVISLVFDLDAPGPGT-MPLADWQEPLA-P--PIRRWRSLPGSPEFLHQEACPFV : ::: :. :: .: :.: .::. : :. : : :: ::::.:::. .. . CCDS65 DTPSKPVLPLVP--PSPFPSTQLPLVTTPETLVQPGTPARRCRSLPSSPELPRRMETALP 400 410 420 430 440 450 480 490 500 510 520 pF1KE0 GREESLSDGPPPRLSSLKYRVK-------EIPPFRASALPAAQAHEAM--DCSILQEENG : ::: : . ... :: : :: : : . . :: CCDS65 G------PGPPAVGPSAEEKMECEGSSPEPEPPGPAPQLPLAVATDNFISTCSSASQPWS 460 470 480 490 500 530 540 550 560 570 pF1KE0 FGSRPQGTSPCPAGASEEMEVEERPAGSTPATFSTSGIGLQTQGKQDG CCDS65 PRSGPVLNNNPPAVVVNSPQGWAGEPWNRAQHSLPRAAALERTEPSPPPSAPREPDEGLP 510 520 530 540 550 560 571 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:46:22 2016 done: Sat Nov 5 04:46:22 2016 Total Scan time: 3.950 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]