FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0983, 588 aa 1>>>pF1KE0983 588 - 588 aa - 588 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.7346+/-0.000451; mu= 4.1143+/- 0.028 mean_var=520.5334+/-118.098, 0's: 0 Z-trim(120.2): 1210 B-trim: 746 in 1/56 Lambda= 0.056215 statistics sampled from 33202 (35085) to 33202 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.738), E-opt: 0.2 (0.411), width: 16 Scan time: 10.750 The best scores are: opt bits E(85289) NP_003573 (OMIM: 603497) dual specificity tyrosine ( 588) 4014 341.2 5.7e-93 NP_001004023 (OMIM: 603497) dual specificity tyros ( 568) 3825 325.8 2.3e-88 XP_005273372 (OMIM: 603497) PREDICTED: dual specif ( 568) 3825 325.8 2.3e-88 XP_011508363 (OMIM: 603497) PREDICTED: dual specif ( 553) 3757 320.3 1e-86 NP_006473 (OMIM: 603496) dual specificity tyrosine ( 601) 2323 204.1 1.1e-51 XP_016875521 (OMIM: 603496) PREDICTED: dual specif ( 528) 2321 203.8 1.2e-51 NP_003574 (OMIM: 603496) dual specificity tyrosine ( 528) 2321 203.8 1.2e-51 NP_003836 (OMIM: 609181) dual specificity tyrosine ( 520) 1237 115.9 3.4e-25 XP_011527787 (OMIM: 600855,614104) PREDICTED: dual ( 725) 975 94.9 9.9e-19 NP_569122 (OMIM: 600855,614104) dual specificity t ( 529) 972 94.4 1e-18 XP_006724042 (OMIM: 600855,614104) PREDICTED: dual ( 754) 975 94.9 1e-18 XP_016883774 (OMIM: 600855,614104) PREDICTED: dual ( 754) 975 94.9 1e-18 XP_016883773 (OMIM: 600855,614104) PREDICTED: dual ( 754) 975 94.9 1e-18 NP_569120 (OMIM: 600855,614104) dual specificity t ( 754) 975 94.9 1e-18 XP_011527786 (OMIM: 600855,614104) PREDICTED: dual ( 761) 975 94.9 1e-18 NP_567824 (OMIM: 600855,614104) dual specificity t ( 584) 972 94.5 1.1e-18 XP_016883775 (OMIM: 600855,614104) PREDICTED: dual ( 734) 972 94.7 1.2e-18 XP_006724040 (OMIM: 600855,614104) PREDICTED: dual ( 763) 972 94.7 1.2e-18 NP_001387 (OMIM: 600855,614104) dual specificity t ( 763) 972 94.7 1.2e-18 XP_006724041 (OMIM: 600855,614104) PREDICTED: dual ( 763) 972 94.7 1.2e-18 XP_011527785 (OMIM: 600855,614104) PREDICTED: dual ( 763) 972 94.7 1.2e-18 XP_006724039 (OMIM: 600855,614104) PREDICTED: dual ( 763) 972 94.7 1.2e-18 XP_011527784 (OMIM: 600855,614104) PREDICTED: dual ( 770) 972 94.7 1.2e-18 NP_004705 (OMIM: 604556,615812) dual specificity t ( 629) 951 92.8 3.6e-18 XP_005259455 (OMIM: 604556,615812) PREDICTED: dual ( 629) 951 92.8 3.6e-18 NP_006474 (OMIM: 604556,615812) dual specificity t ( 589) 871 86.3 3.1e-16 NP_006475 (OMIM: 604556,615812) dual specificity t ( 601) 871 86.3 3.1e-16 XP_005260990 (OMIM: 600855,614104) PREDICTED: dual ( 535) 715 73.6 1.9e-12 XP_016856095 (OMIM: 608003) PREDICTED: homeodomain ( 605) 626 66.5 3e-10 NP_001106710 (OMIM: 606868) homeodomain-interactin (1171) 627 67.0 3.9e-10 XP_006715998 (OMIM: 606868) PREDICTED: homeodomain (1191) 627 67.0 4e-10 XP_016867558 (OMIM: 606868) PREDICTED: homeodomain (1191) 627 67.0 4e-10 NP_073577 (OMIM: 606868) homeodomain-interacting p (1198) 627 67.0 4e-10 NP_689909 (OMIM: 608003) homeodomain-interacting p (1075) 626 66.9 4e-10 XP_011514383 (OMIM: 606868) PREDICTED: homeodomain (1206) 627 67.0 4e-10 XP_011514382 (OMIM: 606868) PREDICTED: homeodomain (1349) 627 67.1 4.2e-10 XP_011514381 (OMIM: 606868) PREDICTED: homeodomain (1350) 627 67.1 4.2e-10 XP_016856094 (OMIM: 608003) PREDICTED: homeodomain (1209) 626 67.0 4.2e-10 NP_938009 (OMIM: 608003) homeodomain-interacting p (1210) 626 67.0 4.2e-10 XP_005270669 (OMIM: 608003) PREDICTED: homeodomain (1210) 626 67.0 4.2e-10 XP_005270670 (OMIM: 608003) PREDICTED: homeodomain (1210) 626 67.0 4.2e-10 XP_011514380 (OMIM: 606868) PREDICTED: homeodomain (1376) 627 67.1 4.3e-10 XP_011514379 (OMIM: 606868) PREDICTED: homeodomain (1377) 627 67.1 4.3e-10 XP_006710506 (OMIM: 608003) PREDICTED: homeodomain (1247) 626 67.0 4.3e-10 XP_005270668 (OMIM: 608003) PREDICTED: homeodomain (1256) 626 67.0 4.3e-10 XP_005270667 (OMIM: 608003) PREDICTED: homeodomain (1280) 626 67.0 4.3e-10 XP_005270666 (OMIM: 608003) PREDICTED: homeodomain (1281) 626 67.0 4.3e-10 NP_001041665 (OMIM: 604424) homeodomain-interactin (1194) 615 66.1 7.8e-10 NP_001265092 (OMIM: 604424) homeodomain-interactin (1194) 615 66.1 7.8e-10 XP_016872566 (OMIM: 604424) PREDICTED: homeodomain (1194) 615 66.1 7.8e-10 >>NP_003573 (OMIM: 603497) dual specificity tyrosine-pho (588 aa) initn: 4014 init1: 4014 opt: 4014 Z-score: 1790.1 bits: 341.2 E(85289): 5.7e-93 Smith-Waterman score: 4014; 100.0% identity (100.0% similar) in 588 aa overlap (1-588:1-588) 10 20 30 40 50 60 pF1KE0 MGGTARGPGRKDAGPPGAGLPPQQRRLGDGVYDTFMMIDETKCPPCSNVLCNPSEPPPPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MGGTARGPGRKDAGPPGAGLPPQQRRLGDGVYDTFMMIDETKCPPCSNVLCNPSEPPPPR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RLNMTTEQFTGDHTQHFLDGGEMKVEQLFQEFGNRKSNTIQSDGISDSEKCSPTVSQGKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 RLNMTTEQFTGDHTQHFLDGGEMKVEQLFQEFGNRKSNTIQSDGISDSEKCSPTVSQGKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SDCLNTVKSNSSSKAPKVVPLTPEQALKQYKHHLTAYEKLEIINYPEIYFVGPNAKKRHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 SDCLNTVKSNSSSKAPKVVPLTPEQALKQYKHHLTAYEKLEIINYPEIYFVGPNAKKRHG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 VIGGPNNGGYDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VIGGPNNGGYDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 RNEKRFHRQAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 RNEKRFHRQAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 KNKFQGFSVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGSSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 KNKFQGFSVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGSSC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FEYQKLYTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 FEYQKLYTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLAC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 MMELLGMPPPKLLEQSKRAKYFINSKGIPRYCSVTTQADGRVVLVGGRSRRGKKRGPPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MMELLGMPPPKLLEQSKRAKYFINSKGIPRYCSVTTQADGRVVLVGGRSRRGKKRGPPGS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 KDWGTALKGCDDYLFIEFLKRCLHWDPSARLTPAQALRHPWISKSVPRPLTTIDKVSGKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 KDWGTALKGCDDYLFIEFLKRCLHWDPSARLTPAQALRHPWISKSVPRPLTTIDKVSGKR 490 500 510 520 530 540 550 560 570 580 pF1KE0 VVNPASAFQGLGSKLPPVVGIANKLKANLMSETNGSIPLCSVLPKLIS :::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VVNPASAFQGLGSKLPPVVGIANKLKANLMSETNGSIPLCSVLPKLIS 550 560 570 580 >>NP_001004023 (OMIM: 603497) dual specificity tyrosine- (568 aa) initn: 3825 init1: 3825 opt: 3825 Z-score: 1707.4 bits: 325.8 E(85289): 2.3e-88 Smith-Waterman score: 3825; 99.5% identity (100.0% similar) in 565 aa overlap (24-588:4-568) 10 20 30 40 50 60 pF1KE0 MGGTARGPGRKDAGPPGAGLPPQQRRLGDGVYDTFMMIDETKCPPCSNVLCNPSEPPPPR ...:::::::::::::::::::::::::::::::::: NP_001 MKWKEKLGDGVYDTFMMIDETKCPPCSNVLCNPSEPPPPR 10 20 30 40 70 80 90 100 110 120 pF1KE0 RLNMTTEQFTGDHTQHFLDGGEMKVEQLFQEFGNRKSNTIQSDGISDSEKCSPTVSQGKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLNMTTEQFTGDHTQHFLDGGEMKVEQLFQEFGNRKSNTIQSDGISDSEKCSPTVSQGKS 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 SDCLNTVKSNSSSKAPKVVPLTPEQALKQYKHHLTAYEKLEIINYPEIYFVGPNAKKRHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDCLNTVKSNSSSKAPKVVPLTPEQALKQYKHHLTAYEKLEIINYPEIYFVGPNAKKRHG 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE0 VIGGPNNGGYDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VIGGPNNGGYDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMV 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE0 RNEKRFHRQAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RNEKRFHRQAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIK 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE0 KNKFQGFSVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGSSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KNKFQGFSVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGSSC 290 300 310 320 330 340 370 380 390 400 410 420 pF1KE0 FEYQKLYTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FEYQKLYTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLAC 350 360 370 380 390 400 430 440 450 460 470 480 pF1KE0 MMELLGMPPPKLLEQSKRAKYFINSKGIPRYCSVTTQADGRVVLVGGRSRRGKKRGPPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MMELLGMPPPKLLEQSKRAKYFINSKGIPRYCSVTTQADGRVVLVGGRSRRGKKRGPPGS 410 420 430 440 450 460 490 500 510 520 530 540 pF1KE0 KDWGTALKGCDDYLFIEFLKRCLHWDPSARLTPAQALRHPWISKSVPRPLTTIDKVSGKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDWGTALKGCDDYLFIEFLKRCLHWDPSARLTPAQALRHPWISKSVPRPLTTIDKVSGKR 470 480 490 500 510 520 550 560 570 580 pF1KE0 VVNPASAFQGLGSKLPPVVGIANKLKANLMSETNGSIPLCSVLPKLIS :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVNPASAFQGLGSKLPPVVGIANKLKANLMSETNGSIPLCSVLPKLIS 530 540 550 560 >>XP_005273372 (OMIM: 603497) PREDICTED: dual specificit (568 aa) initn: 3825 init1: 3825 opt: 3825 Z-score: 1707.4 bits: 325.8 E(85289): 2.3e-88 Smith-Waterman score: 3825; 99.5% identity (100.0% similar) in 565 aa overlap (24-588:4-568) 10 20 30 40 50 60 pF1KE0 MGGTARGPGRKDAGPPGAGLPPQQRRLGDGVYDTFMMIDETKCPPCSNVLCNPSEPPPPR ...:::::::::::::::::::::::::::::::::: XP_005 MKWKEKLGDGVYDTFMMIDETKCPPCSNVLCNPSEPPPPR 10 20 30 40 70 80 90 100 110 120 pF1KE0 RLNMTTEQFTGDHTQHFLDGGEMKVEQLFQEFGNRKSNTIQSDGISDSEKCSPTVSQGKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLNMTTEQFTGDHTQHFLDGGEMKVEQLFQEFGNRKSNTIQSDGISDSEKCSPTVSQGKS 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 SDCLNTVKSNSSSKAPKVVPLTPEQALKQYKHHLTAYEKLEIINYPEIYFVGPNAKKRHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SDCLNTVKSNSSSKAPKVVPLTPEQALKQYKHHLTAYEKLEIINYPEIYFVGPNAKKRHG 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE0 VIGGPNNGGYDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VIGGPNNGGYDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMV 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE0 RNEKRFHRQAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RNEKRFHRQAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIK 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE0 KNKFQGFSVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGSSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KNKFQGFSVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGSSC 290 300 310 320 330 340 370 380 390 400 410 420 pF1KE0 FEYQKLYTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FEYQKLYTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLAC 350 360 370 380 390 400 430 440 450 460 470 480 pF1KE0 MMELLGMPPPKLLEQSKRAKYFINSKGIPRYCSVTTQADGRVVLVGGRSRRGKKRGPPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MMELLGMPPPKLLEQSKRAKYFINSKGIPRYCSVTTQADGRVVLVGGRSRRGKKRGPPGS 410 420 430 440 450 460 490 500 510 520 530 540 pF1KE0 KDWGTALKGCDDYLFIEFLKRCLHWDPSARLTPAQALRHPWISKSVPRPLTTIDKVSGKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KDWGTALKGCDDYLFIEFLKRCLHWDPSARLTPAQALRHPWISKSVPRPLTTIDKVSGKR 470 480 490 500 510 520 550 560 570 580 pF1KE0 VVNPASAFQGLGSKLPPVVGIANKLKANLMSETNGSIPLCSVLPKLIS :::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VVNPASAFQGLGSKLPPVVGIANKLKANLMSETNGSIPLCSVLPKLIS 530 540 550 560 >>XP_011508363 (OMIM: 603497) PREDICTED: dual specificit (553 aa) initn: 3757 init1: 3757 opt: 3757 Z-score: 1677.7 bits: 320.3 E(85289): 1e-86 Smith-Waterman score: 3757; 100.0% identity (100.0% similar) in 553 aa overlap (36-588:1-553) 10 20 30 40 50 60 pF1KE0 RGPGRKDAGPPGAGLPPQQRRLGDGVYDTFMMIDETKCPPCSNVLCNPSEPPPPRRLNMT :::::::::::::::::::::::::::::: XP_011 MMIDETKCPPCSNVLCNPSEPPPPRRLNMT 10 20 30 70 80 90 100 110 120 pF1KE0 TEQFTGDHTQHFLDGGEMKVEQLFQEFGNRKSNTIQSDGISDSEKCSPTVSQGKSSDCLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TEQFTGDHTQHFLDGGEMKVEQLFQEFGNRKSNTIQSDGISDSEKCSPTVSQGKSSDCLN 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 TVKSNSSSKAPKVVPLTPEQALKQYKHHLTAYEKLEIINYPEIYFVGPNAKKRHGVIGGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVKSNSSSKAPKVVPLTPEQALKQYKHHLTAYEKLEIINYPEIYFVGPNAKKRHGVIGGP 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE0 NNGGYDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMVRNEKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NNGGYDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMVRNEKR 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE0 FHRQAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIKKNKFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FHRQAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIKKNKFQ 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE0 GFSVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGSSCFEYQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GFSVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGSSCFEYQK 280 290 300 310 320 330 370 380 390 400 410 420 pF1KE0 LYTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLACMMELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LYTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLACMMELL 340 350 360 370 380 390 430 440 450 460 470 480 pF1KE0 GMPPPKLLEQSKRAKYFINSKGIPRYCSVTTQADGRVVLVGGRSRRGKKRGPPGSKDWGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GMPPPKLLEQSKRAKYFINSKGIPRYCSVTTQADGRVVLVGGRSRRGKKRGPPGSKDWGT 400 410 420 430 440 450 490 500 510 520 530 540 pF1KE0 ALKGCDDYLFIEFLKRCLHWDPSARLTPAQALRHPWISKSVPRPLTTIDKVSGKRVVNPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALKGCDDYLFIEFLKRCLHWDPSARLTPAQALRHPWISKSVPRPLTTIDKVSGKRVVNPA 460 470 480 490 500 510 550 560 570 580 pF1KE0 SAFQGLGSKLPPVVGIANKLKANLMSETNGSIPLCSVLPKLIS ::::::::::::::::::::::::::::::::::::::::::: XP_011 SAFQGLGSKLPPVVGIANKLKANLMSETNGSIPLCSVLPKLIS 520 530 540 550 >>NP_006473 (OMIM: 603496) dual specificity tyrosine-pho (601 aa) initn: 2225 init1: 2174 opt: 2323 Z-score: 1048.8 bits: 204.1 E(85289): 1.1e-51 Smith-Waterman score: 2333; 61.7% identity (83.2% similar) in 564 aa overlap (47-588:40-601) 20 30 40 50 60 70 pF1KE0 GAGLPPQQRRLGDGVYDTFMMIDETKCPPCSNVLCNPSEP---PPPRRLNMTTEQFTGDH :.: .: : :: : : .. : NP_006 APAAYPTGRGGDSAVRQLQASPGLGAGATRSGVGTGPPSPIALPPLRASNAAAAAHTIGG 10 20 30 40 50 60 80 90 100 110 120 pF1KE0 TQHFLDG---------GEMKVEQLFQEFGNRKSN-TIQSDGISDSEKCSPTVSQGKSSDC ..: .. :...:.:::.. .:... : : .:.. : . : .. : NP_006 SKHTMNDHLHVGSHAHGQIQVQQLFEDNSNKRTVLTTQPNGLTTVGKTGLPVVPERQLDS 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 LNTVKSNSSSKAP-------KVVPLTPEQALKQYKHHLTAYEKLEIINYPEIYFVGPNAK .. ...:.: :..:.:::::.::: ..:::.:. ::..::::::.: ::: NP_006 IHRRQGSSTSLKSMEGMGKVKATPMTPEQAMKQYMQKLTAFEHHEIFSYPEIYFLGLNAK 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 KRHGVIGGPNNGGYDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQYVA ::.:. :::::::::: .:.:..::.::.::::::::.:::::::::...::::..:.:: NP_006 KRQGMTGGPNNGGYDDDQGSYVQVPHDHVAYRYEVLKVIGKGSFGQVVKAYDHKVHQHVA 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE0 LKMVRNEKRFHRQAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLY ::::::::::::::::::::::::.:::: ..::::::::.::::::.::.:::::..:: NP_006 LKMVRNEKRFHRQAAEEIRILEHLRKQDKDNTMNVIHMLENFTFRNHICMTFELLSMNLY 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE0 ELIKKNKFQGFSVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDF ::::::::::::. ::::::.:::: :::::::.::::::::::::::..:::. ::::: NP_006 ELIKKNKFQGFSLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILLKQQGRSGIKVIDF 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE0 GSSCFEYQKLYTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGD ::::.:.:..:::::::::::::.:::.::. :::.::.:::::::::: ::.::::::: NP_006 GSSCYEHQRVYTYIQSRFYRAPEVILGARYGMPIDMWSLGCILAELLTGYPLLPGEDEGD 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE0 QLACMMELLGMPPPKLLEQSKRAKYFINSKGIPRYCSVTTQADGRVVLVGGRSRRGKKRG :::::.:::::: :::. ::::: :..::: ::::.::: .:: ::: :::::::: :: NP_006 QLACMIELLGMPSQKLLDASKRAKNFVSSKGYPRYCTVTTLSDGSVVLNGGRSRRGKLRG 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE0 PPGSKDWGTALKGCDDYLFIEFLKRCLHWDPSARLTPAQALRHPWISKSVPRPLTTIDKV :: :..::.::::::: ::..:::.::.:::..:.::.:::::::. . .:.: : .:. NP_006 PPESREWGNALKGCDDPLFLDFLKQCLEWDPAVRMTPGQALRHPWLRRRLPKP-PTGEKT 490 500 510 520 530 540 540 550 560 570 580 pF1KE0 SGKRVVNPASAFQGLGSKLPPVVGIANKLKANL--MSETNGSIPLCSVLPKLIS : ::... ..:. .. ::::: . :.::..:: :...::.: .:::::.: NP_006 SVKRITESTGAITSI-SKLPPPSSSASKLRTNLAQMTDANGNIQQRTVLPKLVS 550 560 570 580 590 600 >>XP_016875521 (OMIM: 603496) PREDICTED: dual specificit (528 aa) initn: 2249 init1: 2174 opt: 2321 Z-score: 1048.4 bits: 203.8 E(85289): 1.2e-51 Smith-Waterman score: 2321; 63.7% identity (86.0% similar) in 535 aa overlap (64-588:1-528) 40 50 60 70 80 90 pF1KE0 TFMMIDETKCPPCSNVLCNPSEPPPPRRLNMTTEQFTGDHTQHFLDGGEMKVEQLFQEFG :. . .:.:.. :...:.:::.. . XP_016 MNDHLHVGSHAH-----GQIQVQQLFEDNS 10 20 100 110 120 130 140 pF1KE0 NRKSN-TIQSDGISDSEKCSPTVSQGKSSDCLNTVKSNSSSKAP-------KVVPLTPEQ :... : : .:.. : . : .. : .. ...:.: :..:.:::: XP_016 NKRTVLTTQPNGLTTVGKTGLPVVPERQLDSIHRRQGSSTSLKSMEGMGKVKATPMTPEQ 30 40 50 60 70 80 150 160 170 180 190 200 pF1KE0 ALKQYKHHLTAYEKLEIINYPEIYFVGPNAKKRHGVIGGPNNGGYDDADGAYIHVPRDHL :.::: ..:::.:. ::..::::::.: :::::.:. :::::::::: .:.:..::.::. XP_016 AMKQYMQKLTAFEHHEIFSYPEIYFLGLNAKKRQGMTGGPNNGGYDDDQGSYVQVPHDHV 90 100 110 120 130 140 210 220 230 240 250 260 pF1KE0 AYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMVRNEKRFHRQAAEEIRILEHLKKQDK ::::::::.:::::::::...::::..:.::::::::::::::::::::::::::.:::: XP_016 AYRYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDK 150 160 170 180 190 200 270 280 290 300 310 320 pF1KE0 TGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIKKNKFQGFSVQLVRKFAQSILQSLDA ..::::::::.::::::.::.:::::..::::::::::::::. ::::::.:::: ::: XP_016 DNTMNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDA 210 220 230 240 250 260 330 340 350 360 370 380 pF1KE0 LHKNKIIHCDLKPENILLKHHGRSSTKVIDFGSSCFEYQKLYTYIQSRFYRAPEIILGSR ::::.::::::::::::::..:::. :::::::::.:.:..:::::::::::::.:::.: XP_016 LHKNRIIHCDLKPENILLKQQGRSGIKVIDFGSSCYEHQRVYTYIQSRFYRAPEVILGAR 270 280 290 300 310 320 390 400 410 420 430 440 pF1KE0 YSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLACMMELLGMPPPKLLEQSKRAKYFINS :. :::.::.:::::::::: ::.::::::::::::.:::::: :::. ::::: :..: XP_016 YGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQKLLDASKRAKNFVSS 330 340 350 360 370 380 450 460 470 480 490 500 pF1KE0 KGIPRYCSVTTQADGRVVLVGGRSRRGKKRGPPGSKDWGTALKGCDDYLFIEFLKRCLHW :: ::::.::: .:: ::: :::::::: :::: :..::.::::::: ::..:::.::.: XP_016 KGYPRYCTVTTLSDGSVVLNGGRSRRGKLRGPPESREWGNALKGCDDPLFLDFLKQCLEW 390 400 410 420 430 440 510 520 530 540 550 560 pF1KE0 DPSARLTPAQALRHPWISKSVPRPLTTIDKVSGKRVVNPASAFQGLGSKLPPVVGIANKL ::..:.::.:::::::. . .:.: : .:.: ::... ..:. .. ::::: . :.:: XP_016 DPAVRMTPGQALRHPWLRRRLPKP-PTGEKTSVKRITESTGAITSI-SKLPPPSSSASKL 450 460 470 480 490 500 570 580 pF1KE0 KANL--MSETNGSIPLCSVLPKLIS ..:: :...::.: .:::::.: XP_016 RTNLAQMTDANGNIQQRTVLPKLVS 510 520 >>NP_003574 (OMIM: 603496) dual specificity tyrosine-pho (528 aa) initn: 2249 init1: 2174 opt: 2321 Z-score: 1048.4 bits: 203.8 E(85289): 1.2e-51 Smith-Waterman score: 2321; 63.7% identity (86.0% similar) in 535 aa overlap (64-588:1-528) 40 50 60 70 80 90 pF1KE0 TFMMIDETKCPPCSNVLCNPSEPPPPRRLNMTTEQFTGDHTQHFLDGGEMKVEQLFQEFG :. . .:.:.. :...:.:::.. . NP_003 MNDHLHVGSHAH-----GQIQVQQLFEDNS 10 20 100 110 120 130 140 pF1KE0 NRKSN-TIQSDGISDSEKCSPTVSQGKSSDCLNTVKSNSSSKAP-------KVVPLTPEQ :... : : .:.. : . : .. : .. ...:.: :..:.:::: NP_003 NKRTVLTTQPNGLTTVGKTGLPVVPERQLDSIHRRQGSSTSLKSMEGMGKVKATPMTPEQ 30 40 50 60 70 80 150 160 170 180 190 200 pF1KE0 ALKQYKHHLTAYEKLEIINYPEIYFVGPNAKKRHGVIGGPNNGGYDDADGAYIHVPRDHL :.::: ..:::.:. ::..::::::.: :::::.:. :::::::::: .:.:..::.::. NP_003 AMKQYMQKLTAFEHHEIFSYPEIYFLGLNAKKRQGMTGGPNNGGYDDDQGSYVQVPHDHV 90 100 110 120 130 140 210 220 230 240 250 260 pF1KE0 AYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMVRNEKRFHRQAAEEIRILEHLKKQDK ::::::::.:::::::::...::::..:.::::::::::::::::::::::::::.:::: NP_003 AYRYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDK 150 160 170 180 190 200 270 280 290 300 310 320 pF1KE0 TGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIKKNKFQGFSVQLVRKFAQSILQSLDA ..::::::::.::::::.::.:::::..::::::::::::::. ::::::.:::: ::: NP_003 DNTMNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDA 210 220 230 240 250 260 330 340 350 360 370 380 pF1KE0 LHKNKIIHCDLKPENILLKHHGRSSTKVIDFGSSCFEYQKLYTYIQSRFYRAPEIILGSR ::::.::::::::::::::..:::. :::::::::.:.:..:::::::::::::.:::.: NP_003 LHKNRIIHCDLKPENILLKQQGRSGIKVIDFGSSCYEHQRVYTYIQSRFYRAPEVILGAR 270 280 290 300 310 320 390 400 410 420 430 440 pF1KE0 YSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLACMMELLGMPPPKLLEQSKRAKYFINS :. :::.::.:::::::::: ::.::::::::::::.:::::: :::. ::::: :..: NP_003 YGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQKLLDASKRAKNFVSS 330 340 350 360 370 380 450 460 470 480 490 500 pF1KE0 KGIPRYCSVTTQADGRVVLVGGRSRRGKKRGPPGSKDWGTALKGCDDYLFIEFLKRCLHW :: ::::.::: .:: ::: :::::::: :::: :..::.::::::: ::..:::.::.: NP_003 KGYPRYCTVTTLSDGSVVLNGGRSRRGKLRGPPESREWGNALKGCDDPLFLDFLKQCLEW 390 400 410 420 430 440 510 520 530 540 550 560 pF1KE0 DPSARLTPAQALRHPWISKSVPRPLTTIDKVSGKRVVNPASAFQGLGSKLPPVVGIANKL ::..:.::.:::::::. . .:.: : .:.: ::... ..:. .. ::::: . :.:: NP_003 DPAVRMTPGQALRHPWLRRRLPKP-PTGEKTSVKRITESTGAITSI-SKLPPPSSSASKL 450 460 470 480 490 500 570 580 pF1KE0 KANL--MSETNGSIPLCSVLPKLIS ..:: :...::.: .:::::.: NP_003 RTNLAQMTDANGNIQQRTVLPKLVS 510 520 >>NP_003836 (OMIM: 609181) dual specificity tyrosine-pho (520 aa) initn: 1395 init1: 1237 opt: 1237 Z-score: 573.4 bits: 115.9 E(85289): 3.4e-25 Smith-Waterman score: 1402; 52.6% identity (76.8% similar) in 409 aa overlap (128-531:23-414) 100 110 120 130 140 150 pF1KE0 NTIQSDGISDSEKCSPTVSQGKSSDCLNTVKSNSSSKAPKVVPLTPEQALKQYKHHLTAY :.. .: . : :: .::: .:..:. : NP_003 MPASELKASEIPFHPSIKTQDPKAEEKSPKKQKVTLTAAEALKLFKNQLSPY 10 20 30 40 50 160 170 180 190 200 210 pF1KE0 EKLEIINYPEIYFVGPNAKKRHGVIGGPNNGGYDDADGAYIHVPRDHLAYRYEVLKIIGK :. ::..: :..:.: .::: . .. ..:: : :..: .::.:::::::. ::: NP_003 EQSEILGYAELWFLGLEAKKLDTAPEKFSKTSFDDEHGFYLKVLHDHIAYRYEVLETIGK 60 70 80 90 100 110 220 230 240 250 260 270 pF1KE0 GSFGQVARVYDHKLRQYVALKMVRNEKRFHRQAAEEIRILEHLKKQDKTGSMNVIHMLES :::::::. ::: . ::::..::.::::.:: :..::: :.:.:: ...::.:: . NP_003 GSFGQVAKCLDHKNNELVALKIIRNKKRFHQQALMELKILEALRKKDKDNTYNVVHMKDF 120 130 140 150 160 170 280 290 300 310 320 330 pF1KE0 FTFRNHVCMAFELLSIDLYELIKKNKFQGFSVQLVRKFAQSILQSLDALHKNKIIHCDLK : :::: :..::::.:.::::.:.:.:::::...::.:. :.:. :. : .:::::::: NP_003 FYFRNHFCITFELLGINLYELMKNNNFQGFSLSIVRRFTLSVLKCLQMLSVEKIIHCDLK 180 190 200 210 220 230 340 350 360 370 380 390 pF1KE0 PENILLKHHGRSSTKVIDFGSSCFEYQKLYTYIQSRFYRAPEIILGSRYSTPIDIWSFGC ::::.: ..:..:.:::::::::.:.::.::::::::::.::.::: :.. ::.::.:: NP_003 PENIVLYQKGQASVKVIDFGSSCYEHQKVYTYIQSRFYRSPEVILGHPYDVAIDMWSLGC 240 250 260 270 280 290 400 410 420 430 440 450 pF1KE0 ILAELLTGQPLFPGEDEGDQLACMMELLGMPPPKLLEQSKRAKYFINSKGIPRYCSVTTQ : ::: :: ::::::.: .::::.::.::.:: ... ..: . :..:::.:. ..:.. NP_003 ITAELYTGYPLFPGENEVEQLACIMEVLGLPPAGFIQTASRRQTFFDSKGFPK--NITNN 300 310 320 330 340 350 460 470 480 490 500 510 pF1KE0 ADGRVVLVGGRSRRGKKRGPPGSKDWGTALKGCDDYLFIEFLKRCLHWDPSARLTPAQAL ::::: : ::: .:: : :..::.::: :.:: :.:: ::: NP_003 -------------RGKKRYPD-SKDLTMVLKTYDTS-FLDFLRRCLVWEPSLRMTPDQAL 360 370 380 390 520 530 540 550 560 570 pF1KE0 RHPWISKSV-----PRPLTTIDKVSGKRVVNPASAFQGLGSKLPPVVGIANKLKANLMSE .: :: .: ::: : NP_003 KHAWIHQSRNLKPQPRPQTLRKSNSFFPSETRKDKVQGCHHSSRKADEITKETTEKTKDS 400 410 420 430 440 450 >>XP_011527787 (OMIM: 600855,614104) PREDICTED: dual spe (725 aa) initn: 925 init1: 470 opt: 975 Z-score: 457.3 bits: 94.9 E(85289): 9.9e-19 Smith-Waterman score: 975; 37.4% identity (66.7% similar) in 444 aa overlap (105-537:19-456) 80 90 100 110 120 130 pF1KE0 QHFLDGGEMKVEQLFQEFGNRKSNTIQSDGISDSEKCSPTVSQGKSSDCLNTVKSNSSSK :::.. . . :. .. : . .. . XP_011 MAGQMPHSHQYSDRRQPNISDQQVSALSYSDQIQQPLTNQRRMPQTFR 10 20 30 40 140 150 160 170 180 190 pF1KE0 APKVVPLTPEQA--LKQYKHHLTAYEKLEIINYPEIYFVGPNAKKRHGVIGGPNNGGYDD : ..:: .. .: ::: .: . . . . ::.. : : :::: XP_011 DPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVY----NDGYDD 50 60 70 80 90 100 200 210 220 230 240 250 pF1KE0 ADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMVRNEKRFHRQAAE . :: .. :::. ..:::::::::...::. ...::.:...:.: : :: XP_011 DNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQI 110 120 130 140 150 160 260 270 280 290 300 310 pF1KE0 EIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIKKNKFQGFSVQLV :.:.:: ..:.: .. ..:. . : ::::.:..::.:: .::.:.....:.: :..:. XP_011 EVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLT 170 180 190 200 210 220 320 330 340 350 360 370 pF1KE0 RKFAQSILQSLD--ALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGSSCFEYQKLYTYI :::::.. .: : . .::::::::::::: . ::. :..:::::: :..: :: XP_011 RKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYI 230 240 250 260 270 280 380 390 400 410 420 430 pF1KE0 QSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLACMMELLGMPPP ::::::.::..:: :. ::.::.::::.:. ::.::: : .: ::. ..:.::.:: XP_011 QSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPA 290 300 310 320 330 340 440 450 460 470 480 pF1KE0 KLLEQSKRAKYFINSKGIPRYC-SVTTQADGRVVLVGGRSRR-----GKKRGPPGSKDWG ..:.:. .:. :... .: .. ::. .:. : . : ::.. : XP_011 HILDQAPKARKFFEK--LPDGTWNLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAG 350 360 370 380 390 400 490 500 510 520 530 540 pF1KE0 TALKGCDDYL-FIEFLKRCLHWDPSARLTPAQALRHPWISKSVPRPLTTIDKVSGKRVVN . . ::: : ... : : .::..:. : ::.: ...:.. . .: ..:: XP_011 ESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEGTNTSNSVSTSPAME 410 420 430 440 450 460 550 560 570 580 pF1KE0 PASAFQGLGSKLPPVVGIANKLKANLMSETNGSIPLCSVLPKLIS XP_011 QSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQHRHSGGHFTAAVQAMDCETHSPQVRQ 470 480 490 500 510 520 >>NP_569122 (OMIM: 600855,614104) dual specificity tyros (529 aa) initn: 980 init1: 470 opt: 972 Z-score: 457.1 bits: 94.4 E(85289): 1e-18 Smith-Waterman score: 972; 36.4% identity (66.0% similar) in 473 aa overlap (90-537:38-494) 60 70 80 90 100 110 pF1KE0 RRLNMTTEQFTGDHTQHFLDGGEMKVEQLFQEFGNRKSNTI---QSDGISDSEKCS-PTV .....:.. .: : ...: :.. . : . NP_569 SACKPSSVRLAPSFSFHAAGLQMAGQMPHSHQYSDRRQPNISDQQVSALSYSDQIQQPLT 10 20 30 40 50 60 120 130 140 150 160 170 pF1KE0 SQGKSSDCLNTVKSNSSSKAPKVVPLTPEQA--LKQYKHHLTAYEKLEIINYPEIYFVGP .: . . . .. . : ..:: .. .: ::: :: :.:.. NP_569 NQVMPDIVMLQRRMPQTFRDPATAPLRKLSVDLIKTYKH----------IN--EVYYA-- 70 80 90 100 110 180 190 200 210 220 pF1KE0 NAKKRHGVIGGPN----------NGGYDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQV . :.:: : . : :::: . :: .. :::. ..::::::::: NP_569 KKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQV 120 130 140 150 160 170 230 240 250 260 270 280 pF1KE0 ARVYDHKLRQYVALKMVRNEKRFHRQAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNH ...::. ...::.:...:.: : :: :.:.:: ..:.: .. ..:. . : :::: NP_569 VKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNH 180 190 200 210 220 230 290 300 310 320 330 340 pF1KE0 VCMAFELLSIDLYELIKKNKFQGFSVQLVRKFAQSILQSLD--ALHKNKIIHCDLKPENI .:..::.:: .::.:.....:.: :..:.:::::.. .: : . .::::::::::: NP_569 LCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENI 240 250 260 270 280 290 350 360 370 380 390 400 pF1KE0 LLKHHGRSSTKVIDFGSSCFEYQKLYTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAE :: . ::. :..:::::: :..: ::::::::.::..:: :. ::.::.::::.: NP_569 LLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVE 300 310 320 330 340 350 410 420 430 440 450 460 pF1KE0 LLTGQPLFPGEDEGDQLACMMELLGMPPPKLLEQSKRAKYFINSKGIPRYC-SVTTQADG . ::.::: : .: ::. ..:.::.:: ..:.:. .:. :... .: .. :: NP_569 MHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEK--LPDGTWNLKKTKDG 360 370 380 390 400 410 470 480 490 500 510 pF1KE0 RVVLVGGRSRR-----GKKRGPPGSKDWGTALKGCDDYL-FIEFLKRCLHWDPSARLTPA . .:. : . : ::.. : . . ::: : ... : : .::..:. : NP_569 KREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPY 420 430 440 450 460 470 520 530 540 550 560 570 pF1KE0 QALRHPWISKSVPRPLTTIDKVSGKRVVNPASAFQGLGSKLPPVVGIANKLKANLMSETN ::.: ...:.. . .: ..:: NP_569 YALQHSFFKKTADEGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGASAISCSSWLVRH 480 490 500 510 520 588 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:47:44 2016 done: Sat Nov 5 04:47:45 2016 Total Scan time: 10.750 Total Display time: 0.120 Function used was FASTA [36.3.4 Apr, 2011]