Result of FASTA (omim) for pF1KE0988
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0988, 619 aa
  1>>>pF1KE0988 619 - 619 aa - 619 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.0995+/-0.000552; mu= 3.7708+/- 0.033
 mean_var=773.0982+/-180.725, 0's: 0 Z-trim(116.8): 1225  B-trim: 0 in 0/61
 Lambda= 0.046127
 statistics sampled from 26531 (28305) to 26531 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.686), E-opt: 0.2 (0.332), width:  16
 Scan time: 11.230

The best scores are:                                      opt bits E(85289)
NP_001070 (OMIM: 176947,269840,617006) tyrosine-pr ( 619) 4255 300.0 1.6e-80
XP_016860356 (OMIM: 176947,269840,617006) PREDICTE ( 742) 4255 300.1 1.7e-80
XP_016860357 (OMIM: 176947,269840,617006) PREDICTE ( 736) 4196 296.2 2.6e-79
XP_016860358 (OMIM: 176947,269840,617006) PREDICTE ( 730) 3975 281.5 7.1e-75
XP_016860359 (OMIM: 176947,269840,617006) PREDICTE ( 707) 3969 281.1 9.2e-75
NP_001128524 (OMIM: 600085) tyrosine-protein kinas ( 612) 2364 174.1 1.2e-42
NP_001167639 (OMIM: 600085) tyrosine-protein kinas ( 612) 2364 174.1 1.2e-42
NP_997402 (OMIM: 176947,269840,617006) tyrosine-pr ( 312) 2135 158.3 3.6e-38
NP_003168 (OMIM: 600085) tyrosine-protein kinase S ( 635) 1094 89.7 3.4e-17
XP_005252204 (OMIM: 600085) PREDICTED: tyrosine-pr ( 635) 1094 89.7 3.4e-17
NP_001167638 (OMIM: 600085) tyrosine-protein kinas ( 635) 1094 89.7 3.4e-17
XP_011517248 (OMIM: 600085) PREDICTED: tyrosine-pr ( 635) 1094 89.7 3.4e-17
XP_016869178 (OMIM: 600758) PREDICTED: focal adhes ( 919)  738 66.3 5.4e-10
XP_016869177 (OMIM: 600758) PREDICTED: focal adhes ( 919)  738 66.3 5.4e-10
XP_016869168 (OMIM: 600758) PREDICTED: focal adhes (1011)  738 66.4 5.7e-10
XP_016869166 (OMIM: 600758) PREDICTED: focal adhes (1032)  738 66.4 5.7e-10
XP_016869179 (OMIM: 600758) PREDICTED: focal adhes ( 913)  736 66.1   6e-10
XP_016869176 (OMIM: 600758) PREDICTED: focal adhes ( 934)  736 66.2   6e-10
XP_016869173 (OMIM: 600758) PREDICTED: focal adhes ( 949)  736 66.2 6.1e-10
XP_016869172 (OMIM: 600758) PREDICTED: focal adhes ( 955)  736 66.2 6.1e-10
NP_001303271 (OMIM: 600758) focal adhesion kinase  ( 955)  736 66.2 6.1e-10
XP_016869170 (OMIM: 600758) PREDICTED: focal adhes ( 980)  736 66.2 6.1e-10
XP_006716673 (OMIM: 600758) PREDICTED: focal adhes ( 983)  736 66.2 6.1e-10
XP_005251070 (OMIM: 600758) PREDICTED: focal adhes ( 983)  736 66.2 6.1e-10
XP_006716672 (OMIM: 600758) PREDICTED: focal adhes ( 983)  736 66.2 6.1e-10
XP_016869169 (OMIM: 600758) PREDICTED: focal adhes ( 995)  736 66.2 6.2e-10
XP_016869164 (OMIM: 600758) PREDICTED: focal adhes (1047)  736 66.2 6.3e-10
XP_016869163 (OMIM: 600758) PREDICTED: focal adhes (1047)  736 66.2 6.3e-10
XP_016869158 (OMIM: 600758) PREDICTED: focal adhes (1059)  736 66.3 6.3e-10
XP_016869156 (OMIM: 600758) PREDICTED: focal adhes (1060)  736 66.3 6.3e-10
XP_016869157 (OMIM: 600758) PREDICTED: focal adhes (1060)  736 66.3 6.3e-10
XP_016869152 (OMIM: 600758) PREDICTED: focal adhes (1062)  736 66.3 6.3e-10
XP_016869151 (OMIM: 600758) PREDICTED: focal adhes (1062)  736 66.3 6.3e-10
XP_016869149 (OMIM: 600758) PREDICTED: focal adhes (1068)  736 66.3 6.4e-10
XP_016869150 (OMIM: 600758) PREDICTED: focal adhes (1068)  736 66.3 6.4e-10
XP_016869141 (OMIM: 600758) PREDICTED: focal adhes (1075)  736 66.3 6.4e-10
XP_016869140 (OMIM: 600758) PREDICTED: focal adhes (1093)  736 66.3 6.4e-10
XP_005251069 (OMIM: 600758) PREDICTED: focal adhes (1096)  736 66.3 6.4e-10
XP_011515496 (OMIM: 600758) PREDICTED: focal adhes (1096)  736 66.3 6.4e-10
XP_006716671 (OMIM: 600758) PREDICTED: focal adhes (1096)  736 66.3 6.4e-10
XP_016869145 (OMIM: 600758) PREDICTED: focal adhes (1103)  736 66.3 6.5e-10
XP_016869144 (OMIM: 600758) PREDICTED: focal adhes (1104)  736 66.3 6.5e-10
XP_016869143 (OMIM: 600758) PREDICTED: focal adhes (1106)  736 66.3 6.5e-10
XP_016869142 (OMIM: 600758) PREDICTED: focal adhes (1112)  736 66.3 6.5e-10
XP_005251060 (OMIM: 600758) PREDICTED: focal adhes (1140)  736 66.3 6.5e-10
XP_016869175 (OMIM: 600758) PREDICTED: focal adhes ( 942)  733 66.0 6.9e-10
XP_016869174 (OMIM: 600758) PREDICTED: focal adhes ( 948)  733 66.0   7e-10
XP_016869171 (OMIM: 600758) PREDICTED: focal adhes ( 976)  733 66.0   7e-10
XP_016869167 (OMIM: 600758) PREDICTED: focal adhes (1016)  733 66.0 7.2e-10
XP_016869148 (OMIM: 600758) PREDICTED: focal adhes (1031)  733 66.0 7.2e-10


>>NP_001070 (OMIM: 176947,269840,617006) tyrosine-protei  (619 aa)
 initn: 4255 init1: 4255 opt: 4255  Z-score: 1566.5  bits: 300.0 E(85289): 1.6e-80
Smith-Waterman score: 4255; 100.0% identity (100.0% similar) in 619 aa overlap (1-619:1-619)

               10        20        30        40        50        60
pF1KE0 MPDPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVRFHHFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPDPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVRFHHFP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 IERQLNGTYAIAGGKAHCGPAELCEFYSRDPDGLPCNLRKPCNRPSGLEPQPGVFDCLRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IERQLNGTYAIAGGKAHCGPAELCEFYSRDPDGLPCNLRKPCNRPSGLEPQPGVFDCLRD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 AMVRDYVRQTWKLEGEALEQAIISQAPQVEKLIATTAHERMPWYHSSLTREEAERKLYSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AMVRDYVRQTWKLEGEALEQAIISQAPQVEKLIATTAHERMPWYHSSLTREEAERKLYSG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 AQTDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQLVEYLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQTDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQLVEYLK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 LKADGLIYCLKEACPNSSASNASGAAAPTLPAHPSTLTHPQRRIDTLNSDGYTPEPARIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKADGLIYCLKEACPNSSASNASGAAAPTLPAHPSTLTHPQRRIDTLNSDGYTPEPARIT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 SPDKPRPMPMDTSVYESPYSDPEELKDKKLFLKRDNLLIADIELGCGNFGSVRQGVYRMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPDKPRPMPMDTSVYESPYSDPEELKDKKLFLKRDNLLIADIELGCGNFGSVRQGVYRMR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE0 KKQIDVAIKVLKQGTEKADTEEMMREAQIMHQLDNPYIVRLIGVCQAEALMLVMEMAGGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKQIDVAIKVLKQGTEKADTEEMMREAQIMHQLDNPYIVRLIGVCQAEALMLVMEMAGGG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE0 PLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDF
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE0 GLSKALGADDSYYTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEALSYGQKPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLSKALGADDSYYTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEALSYGQKPY
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE0 KKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWIYKWEDRPDFLTVEQRMRACYYSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWIYKWEDRPDFLTVEQRMRACYYSL
              550       560       570       580       590       600

              610         
pF1KE0 ASKVEGPPGSTQKAEAACA
       :::::::::::::::::::
NP_001 ASKVEGPPGSTQKAEAACA
              610         

>>XP_016860356 (OMIM: 176947,269840,617006) PREDICTED: t  (742 aa)
 initn: 4255 init1: 4255 opt: 4255  Z-score: 1565.9  bits: 300.1 E(85289): 1.7e-80
Smith-Waterman score: 4255; 100.0% identity (100.0% similar) in 619 aa overlap (1-619:124-742)

                                             10        20        30
pF1KE0                               MPDPAAHLPFFYGSISRAEAEEHLKLAGMA
                                     ::::::::::::::::::::::::::::::
XP_016 WREAGKCVPGRKHPRQEGTGVHEVSGGPGAMPDPAAHLPFFYGSISRAEAEEHLKLAGMA
           100       110       120       130       140       150   

               40        50        60        70        80        90
pF1KE0 DGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIERQLNGTYAIAGGKAHCGPAELCEFYSRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIERQLNGTYAIAGGKAHCGPAELCEFYSRD
           160       170       180       190       200       210   

              100       110       120       130       140       150
pF1KE0 PDGLPCNLRKPCNRPSGLEPQPGVFDCLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDGLPCNLRKPCNRPSGLEPQPGVFDCLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVE
           220       230       240       250       260       270   

              160       170       180       190       200       210
pF1KE0 KLIATTAHERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLIATTAHERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYH
           280       290       300       310       320       330   

              220       230       240       250       260       270
pF1KE0 YLISQDKAGKYCIPEGTKFDTLWQLVEYLKLKADGLIYCLKEACPNSSASNASGAAAPTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLISQDKAGKYCIPEGTKFDTLWQLVEYLKLKADGLIYCLKEACPNSSASNASGAAAPTL
           340       350       360       370       380       390   

              280       290       300       310       320       330
pF1KE0 PAHPSTLTHPQRRIDTLNSDGYTPEPARITSPDKPRPMPMDTSVYESPYSDPEELKDKKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAHPSTLTHPQRRIDTLNSDGYTPEPARITSPDKPRPMPMDTSVYESPYSDPEELKDKKL
           400       410       420       430       440       450   

              340       350       360       370       380       390
pF1KE0 FLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLKQGTEKADTEEMMREAQIM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLKQGTEKADTEEMMREAQIM
           460       470       480       490       500       510   

              400       410       420       430       440       450
pF1KE0 HQLDNPYIVRLIGVCQAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQLDNPYIVRLIGVCQAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMK
           520       530       540       550       560       570   

              460       470       480       490       500       510
pF1KE0 YLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPEC
           580       590       600       610       620       630   

              520       530       540       550       560       570
pF1KE0 INFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYA
           640       650       660       670       680       690   

              580       590       600       610         
pF1KE0 LMSDCWIYKWEDRPDFLTVEQRMRACYYSLASKVEGPPGSTQKAEAACA
       :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMSDCWIYKWEDRPDFLTVEQRMRACYYSLASKVEGPPGSTQKAEAACA
           700       710       720       730       740  

>>XP_016860357 (OMIM: 176947,269840,617006) PREDICTED: t  (736 aa)
 initn: 2262 init1: 2186 opt: 4196  Z-score: 1544.7  bits: 296.2 E(85289): 2.6e-79
Smith-Waterman score: 4196; 99.0% identity (99.0% similar) in 619 aa overlap (1-619:124-736)

                                             10        20        30
pF1KE0                               MPDPAAHLPFFYGSISRAEAEEHLKLAGMA
                                     ::::::::::::::::::::::::::::::
XP_016 WREAGKCVPGRKHPRQEGTGVHEVSGGPGAMPDPAAHLPFFYGSISRAEAEEHLKLAGMA
           100       110       120       130       140       150   

               40        50        60        70        80        90
pF1KE0 DGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIERQLNGTYAIAGGKAHCGPAELCEFYSRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIERQLNGTYAIAGGKAHCGPAELCEFYSRD
           160       170       180       190       200       210   

              100       110       120       130       140       150
pF1KE0 PDGLPCNLRKPCNRPSGLEPQPGVFDCLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDGLPCNLRKPCNRPSGLEPQPGVFDCLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVE
           220       230       240       250       260       270   

              160       170       180       190       200       210
pF1KE0 KLIATTAHERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLIATTAHERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYH
           280       290       300       310       320       330   

              220       230       240       250       260       270
pF1KE0 YLISQDKAGKYCIPEGTKFDTLWQLVEYLKLKADGLIYCLKEACPNSSASNASGAAAPTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLISQDKAGKYCIPEGTKFDTLWQLVEYLKLKADGLIYCLKEACPNSSASNASGAAAPTL
           340       350       360       370       380       390   

              280       290       300       310       320       330
pF1KE0 PAHPSTLTHPQRRIDTLNSDGYTPEPARITSPDKPRPMPMDTSVYESPYSDPEELKDKKL
       ::::::::::::::::::::::::::      ::::::::::::::::::::::::::::
XP_016 PAHPSTLTHPQRRIDTLNSDGYTPEP------DKPRPMPMDTSVYESPYSDPEELKDKKL
           400       410             420       430       440       

              340       350       360       370       380       390
pF1KE0 FLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLKQGTEKADTEEMMREAQIM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLKQGTEKADTEEMMREAQIM
       450       460       470       480       490       500       

              400       410       420       430       440       450
pF1KE0 HQLDNPYIVRLIGVCQAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQLDNPYIVRLIGVCQAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMK
       510       520       530       540       550       560       

              460       470       480       490       500       510
pF1KE0 YLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPEC
       570       580       590       600       610       620       

              520       530       540       550       560       570
pF1KE0 INFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYA
       630       640       650       660       670       680       

              580       590       600       610         
pF1KE0 LMSDCWIYKWEDRPDFLTVEQRMRACYYSLASKVEGPPGSTQKAEAACA
       :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMSDCWIYKWEDRPDFLTVEQRMRACYYSLASKVEGPPGSTQKAEAACA
       690       700       710       720       730      

>>XP_016860358 (OMIM: 176947,269840,617006) PREDICTED: t  (730 aa)
 initn: 3975 init1: 3975 opt: 3975  Z-score: 1465.3  bits: 281.5 E(85289): 7.1e-75
Smith-Waterman score: 3975; 100.0% identity (100.0% similar) in 579 aa overlap (1-579:124-702)

                                             10        20        30
pF1KE0                               MPDPAAHLPFFYGSISRAEAEEHLKLAGMA
                                     ::::::::::::::::::::::::::::::
XP_016 WREAGKCVPGRKHPRQEGTGVHEVSGGPGAMPDPAAHLPFFYGSISRAEAEEHLKLAGMA
           100       110       120       130       140       150   

               40        50        60        70        80        90
pF1KE0 DGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIERQLNGTYAIAGGKAHCGPAELCEFYSRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIERQLNGTYAIAGGKAHCGPAELCEFYSRD
           160       170       180       190       200       210   

              100       110       120       130       140       150
pF1KE0 PDGLPCNLRKPCNRPSGLEPQPGVFDCLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDGLPCNLRKPCNRPSGLEPQPGVFDCLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVE
           220       230       240       250       260       270   

              160       170       180       190       200       210
pF1KE0 KLIATTAHERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLIATTAHERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYH
           280       290       300       310       320       330   

              220       230       240       250       260       270
pF1KE0 YLISQDKAGKYCIPEGTKFDTLWQLVEYLKLKADGLIYCLKEACPNSSASNASGAAAPTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLISQDKAGKYCIPEGTKFDTLWQLVEYLKLKADGLIYCLKEACPNSSASNASGAAAPTL
           340       350       360       370       380       390   

              280       290       300       310       320       330
pF1KE0 PAHPSTLTHPQRRIDTLNSDGYTPEPARITSPDKPRPMPMDTSVYESPYSDPEELKDKKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAHPSTLTHPQRRIDTLNSDGYTPEPARITSPDKPRPMPMDTSVYESPYSDPEELKDKKL
           400       410       420       430       440       450   

              340       350       360       370       380       390
pF1KE0 FLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLKQGTEKADTEEMMREAQIM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLKQGTEKADTEEMMREAQIM
           460       470       480       490       500       510   

              400       410       420       430       440       450
pF1KE0 HQLDNPYIVRLIGVCQAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQLDNPYIVRLIGVCQAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMK
           520       530       540       550       560       570   

              460       470       480       490       500       510
pF1KE0 YLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPEC
           580       590       600       610       620       630   

              520       530       540       550       560       570
pF1KE0 INFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYA
           640       650       660       670       680       690   

              580       590       600       610         
pF1KE0 LMSDCWIYKWEDRPDFLTVEQRMRACYYSLASKVEGPPGSTQKAEAACA
       :::::::::                                        
XP_016 LMSDCWIYKVSSAHADSPLGLCIHRCRCLESSPRPHR            
           700       710       720       730            

>>XP_016860359 (OMIM: 176947,269840,617006) PREDICTED: t  (707 aa)
 initn: 3969 init1: 3969 opt: 3969  Z-score: 1463.2  bits: 281.1 E(85289): 9.2e-75
Smith-Waterman score: 3969; 100.0% identity (100.0% similar) in 578 aa overlap (1-578:124-701)

                                             10        20        30
pF1KE0                               MPDPAAHLPFFYGSISRAEAEEHLKLAGMA
                                     ::::::::::::::::::::::::::::::
XP_016 WREAGKCVPGRKHPRQEGTGVHEVSGGPGAMPDPAAHLPFFYGSISRAEAEEHLKLAGMA
           100       110       120       130       140       150   

               40        50        60        70        80        90
pF1KE0 DGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIERQLNGTYAIAGGKAHCGPAELCEFYSRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIERQLNGTYAIAGGKAHCGPAELCEFYSRD
           160       170       180       190       200       210   

              100       110       120       130       140       150
pF1KE0 PDGLPCNLRKPCNRPSGLEPQPGVFDCLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDGLPCNLRKPCNRPSGLEPQPGVFDCLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVE
           220       230       240       250       260       270   

              160       170       180       190       200       210
pF1KE0 KLIATTAHERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLIATTAHERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYH
           280       290       300       310       320       330   

              220       230       240       250       260       270
pF1KE0 YLISQDKAGKYCIPEGTKFDTLWQLVEYLKLKADGLIYCLKEACPNSSASNASGAAAPTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLISQDKAGKYCIPEGTKFDTLWQLVEYLKLKADGLIYCLKEACPNSSASNASGAAAPTL
           340       350       360       370       380       390   

              280       290       300       310       320       330
pF1KE0 PAHPSTLTHPQRRIDTLNSDGYTPEPARITSPDKPRPMPMDTSVYESPYSDPEELKDKKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAHPSTLTHPQRRIDTLNSDGYTPEPARITSPDKPRPMPMDTSVYESPYSDPEELKDKKL
           400       410       420       430       440       450   

              340       350       360       370       380       390
pF1KE0 FLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLKQGTEKADTEEMMREAQIM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLKQGTEKADTEEMMREAQIM
           460       470       480       490       500       510   

              400       410       420       430       440       450
pF1KE0 HQLDNPYIVRLIGVCQAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQLDNPYIVRLIGVCQAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMK
           520       530       540       550       560       570   

              460       470       480       490       500       510
pF1KE0 YLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPEC
           580       590       600       610       620       630   

              520       530       540       550       560       570
pF1KE0 INFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYA
           640       650       660       670       680       690   

              580       590       600       610         
pF1KE0 LMSDCWIYKWEDRPDFLTVEQRMRACYYSLASKVEGPPGSTQKAEAACA
       ::::::::                                         
XP_016 LMSDCWIYNPSPSS                                   
           700                                          

>>NP_001128524 (OMIM: 600085) tyrosine-protein kinase SY  (612 aa)
 initn: 2251 init1: 1046 opt: 2364  Z-score: 886.5  bits: 174.1 E(85289): 1.2e-42
Smith-Waterman score: 2364; 56.2% identity (80.6% similar) in 608 aa overlap (1-602:6-612)

                    10        20        30        40        50     
pF1KE0      MPDPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVR
            : : : :::::.:.:.: :::..:  .::.:::.::::    :::..::..:  .
NP_001 MASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRK
               10        20        30        40        50        60

          60        70        80        90       100       110     
pF1KE0 FHHFPIERQLNGTYAIAGGKAHCGPAELCEFYSRDPDGLPCNLRKPCNRPSGLEPQPGVF
        ::. :::.::::::::::..: .::.::...:.. ::: : :.:: :::.:..:. : :
NP_001 AHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPF
               70        80        90       100       110       120

         120       130       140       150       160       170     
pF1KE0 DCLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVEKLIATTAHERMPWYHSSLTREEAER
       . :.. ..:.::.:::.:.:.::::::::: ::.::::::::::.:::.:....:::.:.
NP_001 EDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQ
              130       140       150       160       170       180

         180       190       200       210       220       230     
pF1KE0 KLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQL
        .  :..:.::::.: : ..:.::: :..   : :: :..::.::  :::: ::::::::
NP_001 IVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQL
              190       200       210       220       230       240

         240       250        260       270         280       290  
pF1KE0 VEYLKLKADGLIYCLKEACPN-SSASNASGAAAPTLP-AHP-STLTHPQRRIDTLNSDGY
       ::. . :::::.  :   : . .. .:.. .. : :: .:: :. .. .:. .:.. . :
NP_001 VEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPASSPAQGNRQESTVSFNPY
              250       260       270       280       290       300

            300         310       320       330       340       350
pF1KE0 TPEPARITSPDKPR--PMPMDTSVYESPYSDPEELKDKKLFLKRDNLLIADIELGCGNFG
        :: :  ..   :.   .:::: ::::::.::::.. :...: :  : . : ::: ::::
NP_001 EPELAPWAADKGPQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFG
              310       320       330       340       350       360

              360       370        380       390       400         
pF1KE0 SVRQGVYRMRKKQIDVAIKVLK-QGTEKADTEEMMREAQIMHQLDNPYIVRLIGVCQAEA
       .:..: :.:.:    ::.:.:: .... :  .:.. ::..:.:::::::::.::.:.::.
NP_001 TVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAES
              370       380       390       400       410       420

     410       420       430       440       450       460         
pF1KE0 LMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLL
        :::::::  :::.:.:  .:. .  .:. ::.::::::::::::.::::::::::::::
NP_001 WMLVMEMAELGPLNKYLQQNRH-VKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLL
              430       440        450       460       470         

     470       480       490       500       510       520         
pF1KE0 VNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTM
       :..:::::::::::::: ::..:: :.. ::::.:::::::::. ::::.:::::.:: :
NP_001 VTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLM
     480       490       500       510       520       530         

     530       540       550       560       570       580         
pF1KE0 WEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWIYKWEDRPDFLTV
       :::.:::::::. ::: :: :..:.:.:: ::  :: :.: ::. :: :  :.:: : .:
NP_001 WEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAV
     540       550       560       570       580       590         

     590       600       610         
pF1KE0 EQRMRACYYSLASKVEGPPGSTQKAEAACA
       : :.:  ::....                 
NP_001 ELRLRNYYYDVVN                 
     600       610                   

>>NP_001167639 (OMIM: 600085) tyrosine-protein kinase SY  (612 aa)
 initn: 2251 init1: 1046 opt: 2364  Z-score: 886.5  bits: 174.1 E(85289): 1.2e-42
Smith-Waterman score: 2364; 56.2% identity (80.6% similar) in 608 aa overlap (1-602:6-612)

                    10        20        30        40        50     
pF1KE0      MPDPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVR
            : : : :::::.:.:.: :::..:  .::.:::.::::    :::..::..:  .
NP_001 MASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRK
               10        20        30        40        50        60

          60        70        80        90       100       110     
pF1KE0 FHHFPIERQLNGTYAIAGGKAHCGPAELCEFYSRDPDGLPCNLRKPCNRPSGLEPQPGVF
        ::. :::.::::::::::..: .::.::...:.. ::: : :.:: :::.:..:. : :
NP_001 AHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPF
               70        80        90       100       110       120

         120       130       140       150       160       170     
pF1KE0 DCLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVEKLIATTAHERMPWYHSSLTREEAER
       . :.. ..:.::.:::.:.:.::::::::: ::.::::::::::.:::.:....:::.:.
NP_001 EDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQ
              130       140       150       160       170       180

         180       190       200       210       220       230     
pF1KE0 KLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQL
        .  :..:.::::.: : ..:.::: :..   : :: :..::.::  :::: ::::::::
NP_001 IVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQL
              190       200       210       220       230       240

         240       250        260       270         280       290  
pF1KE0 VEYLKLKADGLIYCLKEACPN-SSASNASGAAAPTLP-AHP-STLTHPQRRIDTLNSDGY
       ::. . :::::.  :   : . .. .:.. .. : :: .:: :. .. .:. .:.. . :
NP_001 VEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPASSPAQGNRQESTVSFNPY
              250       260       270       280       290       300

            300         310       320       330       340       350
pF1KE0 TPEPARITSPDKPR--PMPMDTSVYESPYSDPEELKDKKLFLKRDNLLIADIELGCGNFG
        :: :  ..   :.   .:::: ::::::.::::.. :...: :  : . : ::: ::::
NP_001 EPELAPWAADKGPQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFG
              310       320       330       340       350       360

              360       370        380       390       400         
pF1KE0 SVRQGVYRMRKKQIDVAIKVLK-QGTEKADTEEMMREAQIMHQLDNPYIVRLIGVCQAEA
       .:..: :.:.:    ::.:.:: .... :  .:.. ::..:.:::::::::.::.:.::.
NP_001 TVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAES
              370       380       390       400       410       420

     410       420       430       440       450       460         
pF1KE0 LMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLL
        :::::::  :::.:.:  .:. .  .:. ::.::::::::::::.::::::::::::::
NP_001 WMLVMEMAELGPLNKYLQQNRH-VKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLL
              430       440        450       460       470         

     470       480       490       500       510       520         
pF1KE0 VNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTM
       :..:::::::::::::: ::..:: :.. ::::.:::::::::. ::::.:::::.:: :
NP_001 VTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLM
     480       490       500       510       520       530         

     530       540       550       560       570       580         
pF1KE0 WEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWIYKWEDRPDFLTV
       :::.:::::::. ::: :: :..:.:.:: ::  :: :.: ::. :: :  :.:: : .:
NP_001 WEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAV
     540       550       560       570       580       590         

     590       600       610         
pF1KE0 EQRMRACYYSLASKVEGPPGSTQKAEAACA
       : :.:  ::....                 
NP_001 ELRLRNYYYDVVN                 
     600       610                   

>>NP_997402 (OMIM: 176947,269840,617006) tyrosine-protei  (312 aa)
 initn: 2135 init1: 2135 opt: 2135  Z-score: 806.3  bits: 158.3 E(85289): 3.6e-38
Smith-Waterman score: 2135; 100.0% identity (100.0% similar) in 312 aa overlap (308-619:1-312)

       280       290       300       310       320       330       
pF1KE0 THPQRRIDTLNSDGYTPEPARITSPDKPRPMPMDTSVYESPYSDPEELKDKKLFLKRDNL
                                     ::::::::::::::::::::::::::::::
NP_997                               MPMDTSVYESPYSDPEELKDKKLFLKRDNL
                                             10        20        30

       340       350       360       370       380       390       
pF1KE0 LIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLKQGTEKADTEEMMREAQIMHQLDNPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 LIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLKQGTEKADTEEMMREAQIMHQLDNPY
               40        50        60        70        80        90

       400       410       420       430       440       450       
pF1KE0 IVRLIGVCQAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 IVRLIGVCQAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKNF
              100       110       120       130       140       150

       460       470       480       490       500       510       
pF1KE0 VHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECINFRKFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 VHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECINFRKFS
              160       170       180       190       200       210

       520       530       540       550       560       570       
pF1KE0 SRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 SRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWI
              220       230       240       250       260       270

       580       590       600       610         
pF1KE0 YKWEDRPDFLTVEQRMRACYYSLASKVEGPPGSTQKAEAACA
       ::::::::::::::::::::::::::::::::::::::::::
NP_997 YKWEDRPDFLTVEQRMRACYYSLASKVEGPPGSTQKAEAACA
              280       290       300       310  

>>NP_003168 (OMIM: 600085) tyrosine-protein kinase SYK i  (635 aa)
 initn: 2251 init1: 1046 opt: 1094  Z-score: 429.6  bits: 89.7 E(85289): 3.4e-17
Smith-Waterman score: 2324; 54.4% identity (77.7% similar) in 631 aa overlap (1-602:6-635)

                    10        20        30        40        50     
pF1KE0      MPDPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVR
            : : : :::::.:.:.: :::..:  .::.:::.::::    :::..::..:  .
NP_003 MASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRK
               10        20        30        40        50        60

          60        70        80        90       100       110     
pF1KE0 FHHFPIERQLNGTYAIAGGKAHCGPAELCEFYSRDPDGLPCNLRKPCNRPSGLEPQPGVF
        ::. :::.::::::::::..: .::.::...:.. ::: : :.:: :::.:..:. : :
NP_003 AHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPF
               70        80        90       100       110       120

         120       130       140       150       160       170     
pF1KE0 DCLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVEKLIATTAHERMPWYHSSLTREEAER
       . :.. ..:.::.:::.:.:.::::::::: ::.::::::::::.:::.:....:::.:.
NP_003 EDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQ
              130       140       150       160       170       180

         180       190       200       210       220       230     
pF1KE0 KLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQL
        .  :..:.::::.: : ..:.::: :..   : :: :..::.::  :::: ::::::::
NP_003 IVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQL
              190       200       210       220       230       240

         240       250        260       270                    280 
pF1KE0 VEYLKLKADGLIYCLKEACPN-SSASNASGAAAPTLP-AHPST------------LTHPQ
       ::. . :::::.  :   : . .. .:.. .. : :: .::.:             . :.
NP_003 VEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPATWSAGGIISRIKSYSFPK
              250       260       270       280       290       300

                         290       300         310       320       
pF1KE0 ------------RRIDTLNSDGYTPEPARITSPDKPR--PMPMDTSVYESPYSDPEELKD
                   :. .:.. . : :: :  ..   :.   .:::: ::::::.::::.. 
NP_003 PGHRKSSPAQGNRQESTVSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRP
              310       320       330       340       350       360

       330       340       350       360       370        380      
pF1KE0 KKLFLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLK-QGTEKADTEEMMRE
       :...: :  : . : ::: ::::.:..: :.:.:    ::.:.:: .... :  .:.. :
NP_003 KEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAE
              370       380       390       400       410       420

        390       400       410       420       430       440      
pF1KE0 AQIMHQLDNPYIVRLIGVCQAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVS
       :..:.:::::::::.::.:.::. :::::::  :::.:.:  .:. .  .:. ::.::::
NP_003 ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRH-VKDKNIIELVHQVS
              430       440       450       460        470         

        450       460       470       480       490       500      
pF1KE0 MGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWY
       ::::::::.:::::::::::::::..:::::::::::::: ::..:: :.. ::::.:::
NP_003 MGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWY
     480       490       500       510       520       530         

        510       520       530       540       550       560      
pF1KE0 APECINFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPP
       ::::::. ::::.:::::.:: ::::.:::::::. ::: :: :..:.:.:: ::  :: 
NP_003 APECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPR
     540       550       560       570       580       590         

        570       580       590       600       610         
pF1KE0 ELYALMSDCWIYKWEDRPDFLTVEQRMRACYYSLASKVEGPPGSTQKAEAACA
       :.: ::. :: :  :.:: : .:: :.:  ::....                 
NP_003 EMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN                 
     600       610       620       630                      

>>XP_005252204 (OMIM: 600085) PREDICTED: tyrosine-protei  (635 aa)
 initn: 2251 init1: 1046 opt: 1094  Z-score: 429.6  bits: 89.7 E(85289): 3.4e-17
Smith-Waterman score: 2324; 54.4% identity (77.7% similar) in 631 aa overlap (1-602:6-635)

                    10        20        30        40        50     
pF1KE0      MPDPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVR
            : : : :::::.:.:.: :::..:  .::.:::.::::    :::..::..:  .
XP_005 MASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRK
               10        20        30        40        50        60

          60        70        80        90       100       110     
pF1KE0 FHHFPIERQLNGTYAIAGGKAHCGPAELCEFYSRDPDGLPCNLRKPCNRPSGLEPQPGVF
        ::. :::.::::::::::..: .::.::...:.. ::: : :.:: :::.:..:. : :
XP_005 AHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPF
               70        80        90       100       110       120

         120       130       140       150       160       170     
pF1KE0 DCLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVEKLIATTAHERMPWYHSSLTREEAER
       . :.. ..:.::.:::.:.:.::::::::: ::.::::::::::.:::.:....:::.:.
XP_005 EDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQ
              130       140       150       160       170       180

         180       190       200       210       220       230     
pF1KE0 KLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQL
        .  :..:.::::.: : ..:.::: :..   : :: :..::.::  :::: ::::::::
XP_005 IVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQL
              190       200       210       220       230       240

         240       250        260       270                    280 
pF1KE0 VEYLKLKADGLIYCLKEACPN-SSASNASGAAAPTLP-AHPST------------LTHPQ
       ::. . :::::.  :   : . .. .:.. .. : :: .::.:             . :.
XP_005 VEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPATWSAGGIISRIKSYSFPK
              250       260       270       280       290       300

                         290       300         310       320       
pF1KE0 ------------RRIDTLNSDGYTPEPARITSPDKPR--PMPMDTSVYESPYSDPEELKD
                   :. .:.. . : :: :  ..   :.   .:::: ::::::.::::.. 
XP_005 PGHRKSSPAQGNRQESTVSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRP
              310       320       330       340       350       360

       330       340       350       360       370        380      
pF1KE0 KKLFLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLK-QGTEKADTEEMMRE
       :...: :  : . : ::: ::::.:..: :.:.:    ::.:.:: .... :  .:.. :
XP_005 KEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAE
              370       380       390       400       410       420

        390       400       410       420       430       440      
pF1KE0 AQIMHQLDNPYIVRLIGVCQAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVS
       :..:.:::::::::.::.:.::. :::::::  :::.:.:  .:. .  .:. ::.::::
XP_005 ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRH-VKDKNIIELVHQVS
              430       440       450       460        470         

        450       460       470       480       490       500      
pF1KE0 MGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWY
       ::::::::.:::::::::::::::..:::::::::::::: ::..:: :.. ::::.:::
XP_005 MGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWY
     480       490       500       510       520       530         

        510       520       530       540       550       560      
pF1KE0 APECINFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPP
       ::::::. ::::.:::::.:: ::::.:::::::. ::: :: :..:.:.:: ::  :: 
XP_005 APECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPR
     540       550       560       570       580       590         

        570       580       590       600       610         
pF1KE0 ELYALMSDCWIYKWEDRPDFLTVEQRMRACYYSLASKVEGPPGSTQKAEAACA
       :.: ::. :: :  :.:: : .:: :.:  ::....                 
XP_005 EMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN                 
     600       610       620       630                      




619 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 18:03:20 2016 done: Sat Nov  5 18:03:22 2016
 Total Scan time: 11.230 Total Display time:  0.160

Function used was FASTA [36.3.4 Apr, 2011]
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