Result of FASTA (ccds) for
pF1KE0989
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0989, 623 aa
1>>>pF1KE0989 623 - 623 aa - 623 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.5622+/-0.00134; mu= -4.2869+/- 0.079
mean_var=379.4678+/-81.849, 0's: 0 Z-trim(110.6): 606 B-trim: 391 in 1/52
Lambda= 0.065840
statistics sampled from 11051 (11753) to 11051 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.702), E-opt: 0.2 (0.361), width: 16
Scan time: 3.860
The best scores are: opt bits E(32554)
CCDS4516.1 MAK gene_id:4117|Hs108|chr6 ( 623) 4217 415.4 1.1e-115
CCDS75398.1 MAK gene_id:4117|Hs108|chr6 ( 583) 3602 356.9 4.2e-98
CCDS75399.1 MAK gene_id:4117|Hs108|chr6 ( 648) 3600 356.8 5.2e-98
CCDS4949.1 ICK gene_id:22858|Hs108|chr6 ( 632) 1916 196.8 7.2e-50
CCDS9971.1 MOK gene_id:5891|Hs108|chr14 ( 419) 761 86.9 5.8e-17
CCDS81854.1 MOK gene_id:5891|Hs108|chr14 ( 418) 757 86.5 7.5e-17
CCDS44408.1 CDK1 gene_id:983|Hs108|chr10 ( 297) 753 86.0 7.7e-17
CCDS8898.1 CDK2 gene_id:1017|Hs108|chr12 ( 298) 750 85.7 9.4e-17
CCDS11736.1 CDK3 gene_id:1018|Hs108|chr17 ( 305) 743 85.1 1.5e-16
CCDS9061.1 CDK17 gene_id:5128|Hs108|chr12 ( 523) 745 85.5 1.9e-16
CCDS53819.1 CDK17 gene_id:5128|Hs108|chr12 ( 523) 745 85.5 1.9e-16
CCDS44300.1 CDK18 gene_id:5129|Hs108|chr1 ( 474) 700 81.2 3.5e-15
CCDS1454.1 CDK18 gene_id:5129|Hs108|chr1 ( 504) 700 81.2 3.6e-15
CCDS9699.1 CDKL1 gene_id:8814|Hs108|chr14 ( 358) 689 80.0 5.9e-15
CCDS14276.1 CDK16 gene_id:5127|Hs108|chrX ( 496) 679 79.2 1.4e-14
CCDS48101.1 CDK16 gene_id:5127|Hs108|chrX ( 502) 679 79.2 1.4e-14
CCDS55408.1 CDK16 gene_id:5127|Hs108|chrX ( 570) 679 79.3 1.6e-14
CCDS35060.1 CDK20 gene_id:23552|Hs108|chr9 ( 346) 660 77.3 3.9e-14
CCDS83458.1 CDKL5 gene_id:6792|Hs108|chrX ( 960) 665 78.2 5.7e-14
CCDS14186.1 CDKL5 gene_id:6792|Hs108|chrX (1030) 665 78.2 6e-14
CCDS3999.1 CDK7 gene_id:1022|Hs108|chr5 ( 346) 649 76.2 8e-14
CCDS13795.1 MAPK1 gene_id:5594|Hs108|chr22 ( 360) 648 76.1 8.8e-14
CCDS3570.1 CDKL2 gene_id:8999|Hs108|chr4 ( 493) 645 76.0 1.3e-13
CCDS82933.1 CDKL2 gene_id:8999|Hs108|chr4 ( 570) 645 76.0 1.5e-13
CCDS33184.1 CDKL4 gene_id:344387|Hs108|chr2 ( 315) 635 74.8 1.9e-13
CCDS2350.1 CDK15 gene_id:65061|Hs108|chr2 ( 384) 637 75.1 1.9e-13
CCDS47748.1 CDK5 gene_id:1020|Hs108|chr7 ( 292) 634 74.7 1.9e-13
CCDS10984.2 CDK10 gene_id:8558|Hs108|chr16 ( 360) 636 75.0 1.9e-13
CCDS58746.1 CDK15 gene_id:65061|Hs108|chr2 ( 400) 637 75.1 2e-13
CCDS58747.1 CDK15 gene_id:65061|Hs108|chr2 ( 429) 637 75.2 2.1e-13
CCDS75627.1 CDK14 gene_id:5218|Hs108|chr7 ( 423) 626 74.1 4.2e-13
CCDS5619.1 CDK14 gene_id:5218|Hs108|chr7 ( 451) 626 74.1 4.4e-13
CCDS75626.1 CDK14 gene_id:5218|Hs108|chr7 ( 469) 626 74.2 4.5e-13
CCDS42149.1 MAPK3 gene_id:5595|Hs108|chr16 ( 357) 619 73.4 5.9e-13
CCDS44043.1 CDK11A gene_id:728642|Hs108|chr1 ( 770) 627 74.5 6e-13
CCDS81254.1 CDK11A gene_id:728642|Hs108|chr1 ( 779) 627 74.5 6e-13
CCDS44042.1 CDK11A gene_id:728642|Hs108|chr1 ( 780) 627 74.5 6e-13
CCDS81253.1 CDK11A gene_id:728642|Hs108|chr1 ( 783) 627 74.5 6e-13
CCDS10672.1 MAPK3 gene_id:5595|Hs108|chr16 ( 379) 619 73.4 6.2e-13
CCDS73637.1 CDKL1 gene_id:8814|Hs108|chr14 ( 276) 615 72.9 6.4e-13
CCDS72682.1 CDK11B gene_id:984|Hs108|chr1 ( 748) 624 74.2 7.1e-13
CCDS72684.1 CDK11B gene_id:984|Hs108|chr1 ( 782) 624 74.2 7.4e-13
CCDS72683.1 CDK11B gene_id:984|Hs108|chr1 ( 795) 624 74.2 7.4e-13
CCDS61552.1 MOK gene_id:5891|Hs108|chr14 ( 389) 611 72.7 1.1e-12
CCDS14089.1 MAPK12 gene_id:6300|Hs108|chr22 ( 367) 602 71.8 1.8e-12
CCDS4818.1 MAPK13 gene_id:5603|Hs108|chr6 ( 365) 595 71.1 2.9e-12
CCDS4816.1 MAPK14 gene_id:1432|Hs108|chr6 ( 360) 593 70.9 3.3e-12
CCDS47265.1 CDKL3 gene_id:51265|Hs108|chr5 ( 455) 591 70.8 4.4e-12
CCDS47264.1 CDKL3 gene_id:51265|Hs108|chr5 ( 592) 591 70.9 5.3e-12
CCDS4815.1 MAPK14 gene_id:1432|Hs108|chr6 ( 360) 584 70.1 6e-12
>>CCDS4516.1 MAK gene_id:4117|Hs108|chr6 (623 aa)
initn: 4217 init1: 4217 opt: 4217 Z-score: 2190.0 bits: 415.4 E(32554): 1.1e-115
Smith-Waterman score: 4217; 100.0% identity (100.0% similar) in 623 aa overlap (1-623:1-623)
10 20 30 40 50 60
pF1KE0 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 QSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 QSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 QQSQEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 QQSQEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 KKPSMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 KKPSMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 LKQSRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNAGNLGSYAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LKQSRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNAGNLGSYAT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 YNQSGYIPSFLKKEVQSAGQRIHLAPLNATASEYTWNTKTGRGQFSGRTYNPTAKNLNIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 YNQSGYIPSFLKKEVQSAGQRIHLAPLNATASEYTWNTKTGRGQFSGRTYNPTAKNLNIV
550 560 570 580 590 600
610 620
pF1KE0 NRAQPIPSVHGRTDWVAKYGGHR
:::::::::::::::::::::::
CCDS45 NRAQPIPSVHGRTDWVAKYGGHR
610 620
>>CCDS75398.1 MAK gene_id:4117|Hs108|chr6 (583 aa)
initn: 3600 init1: 3600 opt: 3602 Z-score: 1874.7 bits: 356.9 E(32554): 4.2e-98
Smith-Waterman score: 3871; 93.6% identity (93.6% similar) in 623 aa overlap (1-623:1-583)
10 20 30 40 50 60
pF1KE0 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 QSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 QSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 QQSQEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 QQSQEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 KKPSMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 KKPSMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 LKQSRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNAGNLGSYAT
::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 LKQSRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNA--------
490 500 510 520 530
550 560 570 580 590 600
pF1KE0 YNQSGYIPSFLKKEVQSAGQRIHLAPLNATASEYTWNTKTGRGQFSGRTYNPTAKNLNIV
::::::::::::::::::::::::::::
CCDS75 --------------------------------EYTWNTKTGRGQFSGRTYNPTAKNLNIV
540 550 560
610 620
pF1KE0 NRAQPIPSVHGRTDWVAKYGGHR
:::::::::::::::::::::::
CCDS75 NRAQPIPSVHGRTDWVAKYGGHR
570 580
>>CCDS75399.1 MAK gene_id:4117|Hs108|chr6 (648 aa)
initn: 4203 init1: 3600 opt: 3600 Z-score: 1873.1 bits: 356.8 E(32554): 5.2e-98
Smith-Waterman score: 4157; 96.1% identity (96.1% similar) in 648 aa overlap (1-623:1-648)
10 20 30 40 50 60
pF1KE0 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 QSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 QSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 QQSQEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 QQSQEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 KKPSMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 KKPSMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYY
430 440 450 460 470 480
490 500 510 520 530
pF1KE0 LKQSRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNA--------
::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 LKQSRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNAEESIIKPI
490 500 510 520 530 540
540 550 560 570
pF1KE0 -----------------GNLGSYATYNQSGYIPSFLKKEVQSAGQRIHLAPLNATASEYT
:::::::::::::::::::::::::::::::::::::::::::
CCDS75 EKLSCNETFPEKLEDPQGNLGSYATYNQSGYIPSFLKKEVQSAGQRIHLAPLNATASEYT
550 560 570 580 590 600
580 590 600 610 620
pF1KE0 WNTKTGRGQFSGRTYNPTAKNLNIVNRAQPIPSVHGRTDWVAKYGGHR
::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 WNTKTGRGQFSGRTYNPTAKNLNIVNRAQPIPSVHGRTDWVAKYGGHR
610 620 630 640
>>CCDS4949.1 ICK gene_id:22858|Hs108|chr6 (632 aa)
initn: 2130 init1: 1821 opt: 1916 Z-score: 1008.8 bits: 196.8 E(32554): 7.2e-50
Smith-Waterman score: 2285; 56.3% identity (77.9% similar) in 639 aa overlap (1-623:1-632)
10 20 30 40 50 60
pF1KE0 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA
::::::.::::::::::::.:.: :::::.:::.::::::::.:::::::::::::::::
CCDS49 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG
::.::::::::::::::::::::::::::.:.::::::::.:::::::::::::::::::
CCDS49 NVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP
:::::.:::::::::::::::::::::::.::.:::::::::::::::::::::. ::::
CCDS49 FFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSSP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ
::::::: ::::.: :::::::.::.: :::::::::::::.::::::::.:.::::.::
CCDS49 IDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRWPQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESK
::: ::::::::::.::.::. .::.:::::::::::::..::::::. :: ....:...
CCDS49 CVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQNLQDS
250 260 270 280 290 300
310 320 330 340 350
pF1KE0 QSLNKQLQPLESKPSLVEVEPKPLPDIIDQV-VGQPQPKTSQQPLQPIQPPQ-NLSVQQP
.. .: . . : .. : : .. ... : ..:: ::. : . ..: .
CCDS49 EKPQKGILEKAGPPPYIKPVPPAQPPAKPHTRISSRQHQASQPPLHLTYPYKAEVSRTDH
310 320 330 340 350 360
360 370 380 390 400
pF1KE0 PKQQSQEKPPQTLFPSIVKNMP-TKPNGTLSHKSG------RRRWG--QTIFKSGDSWEE
:.. ...:: ::::. .. : .: .. : ::.: ::::: . :..:.: .
CCDS49 PSHLQEDKPSPLLFPSLHNKHPQSKITAGLEHKNGEIKPKSRRRWGLISRSTKDSDDWAD
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE0 LEDYDFGASHSKKPSMGVFKEKRKKDSPF-RLPEPVPSGSNHSTGENKSLPAVTSLKSDS
:.: ::. : :. . . ..::..:. . :. . .. .: ..: :. :: . .
CCDS49 LDDLDFSPSLSR---IDLKNKKRQSDDTLCRFESVLDLKPSEPVGTGNSAPTQTSYQRRD
430 440 450 460 470
470 480 490 500 510 520
pF1KE0 ELSTAPTSKQYYLKQSRYLPGVNPKKVSLIASGKE-INPHTWSNQ-LFPKSLGPVGAELA
. ..::.:::.::::::.. .. : ::: : :. ::.. : :: : .. .
CCDS49 TPTLRSAAKQHYLKHSRYLPGISIRNGILSNPGKEFIPPNPWSSSGLSGKSSGTMS--VI
480 490 500 510 520 530
530 540 550 560 570 580
pF1KE0 FKRSNAGNLGSYATYNQSGYIPSFLKKEVQSAGQRIHLAPLNATASEYTWNTKTGRGQFS
: ...:. .. .. ..:.:::::::. :: ::.::::. . :. . :. : .
CCDS49 SKVNSVGSSSTSSSGLTGNYVPSFLKKEIGSAMQRVHLAPIPDPSPGYS-SLKAMRPH-P
540 550 560 570 580 590
590 600 610 620
pF1KE0 GRTYNPTA--KNLNIVNRAQPIPSVHGRTDWVAKYGGHR
:: . : .. ... : :::::::..::...:
CCDS49 GRPFFHTQPRSTPGLIPRPPAAQPVHGRTDWASKYASRR
600 610 620 630
>>CCDS9971.1 MOK gene_id:5891|Hs108|chr14 (419 aa)
initn: 673 init1: 297 opt: 761 Z-score: 418.1 bits: 86.9 E(32554): 5.8e-17
Smith-Waterman score: 761; 40.3% identity (71.5% similar) in 288 aa overlap (1-285:1-286)
10 20 30 40 50
pF1KE0 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLN-H
:. : .. ..:.::.. :. .: ..:. : :.::..: : .. ::::...:..:: :
CCDS99 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLNPH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 ANVIKLKEVI--RENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIH
:.. :.::. :.. : .: : : :.:.:.. : . :. : . :::. ..: ::
CCDS99 PNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIH
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 KHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVY
..:.::::.::::.: . ...:..::: : . :. :::.:.::::::::: :: .. :
CCDS99 RNGIFHRDVKPENIL-IKQDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFY
130 140 150 160 170
180 190 200 210 220 230
pF1KE0 SSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFR
. .:.:..: .. :. :.:::::..:.:.: :: .:.::: .. . .. . .:::
CCDS99 TYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTK-FKQSRAMNFD
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 FPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHL
:: .. : : : . ..:. :. .:: .: .: :::.:::::
CCDS99 FPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQEQRKTEKRALGS
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 ESKQSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQ
CCDS99 HRKAGFPEHPVAPEPLSNSCQISKEGRKQKQSLKQEEDRPKRRGPAYVMELPKLKLSGVV
300 310 320 330 340 350
>>CCDS81854.1 MOK gene_id:5891|Hs108|chr14 (418 aa)
initn: 667 init1: 297 opt: 757 Z-score: 416.0 bits: 86.5 E(32554): 7.5e-17
Smith-Waterman score: 757; 40.3% identity (71.2% similar) in 288 aa overlap (1-285:1-285)
10 20 30 40 50
pF1KE0 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLN-H
:. : .. ..:.::.. :. .: ..:. : :.::..: : .. ::::...:..:: :
CCDS81 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLNPH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 ANVIKLKEVI--RENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIH
:.. :.::. :.. : .: : : :.:.:.. : . :. : . :::. ..: ::
CCDS81 PNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIH
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 KHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVY
..:.::::.::::.: ...:..::: : . :. :::.:.::::::::: :: .. :
CCDS81 RNGIFHRDVKPENILI--KDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFY
130 140 150 160 170
180 190 200 210 220 230
pF1KE0 SSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFR
. .:.:..: .. :. :.:::::..:.:.: :: .:.::: .. . .. . .:::
CCDS81 TYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTK-FKQSRAMNFD
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 FPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHL
:: .. : : : . ..:. :. .:: .: .: :::.:::::
CCDS81 FPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQEQRKTEKRALGS
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 ESKQSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQ
CCDS81 HRKAGFPEHPVAPEPLSNSCQISKEGRKQKQSLKQEEDRPKRRGPAYVMELPKLKLSGVV
300 310 320 330 340 350
>>CCDS44408.1 CDK1 gene_id:983|Hs108|chr10 (297 aa)
initn: 491 init1: 290 opt: 753 Z-score: 415.8 bits: 86.0 E(32554): 7.7e-17
Smith-Waterman score: 753; 39.9% identity (73.5% similar) in 291 aa overlap (1-284:1-287)
10 20 30 40 50
pF1KE0 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECM---NLREVKSLKKL
:. :: ....:.:::: : :. . .:..::.:.. .. : .: . .::.. ::.:
CCDS44 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKI--RLESEEEGVPSTAIREISLLKEL
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 NHANVIKLKEVIRENDHLYFIFEYMKENLYQLMKD--RNKLFPESVIRNIMYQILQGLAF
: :...:..:. ....::.:::... .: . . . .. . :.... .::::::..:
CCDS44 RHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 IHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPP--YTDYVSTRWYRAPEVLLR
:.. .:::.::.::: .:.::::::: . . : :: : : :::.:::::
CCDS44 CHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAF-GIPIRVYTHEVVTLWYRSPEVLLG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 SSVYSSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASS
:. ::.:.:.:..:.:.::: .::: : ::.:..:.: ..::::.. ::: .: .
CCDS44 SARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDY
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 MNFRFPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPS
: ::. : .: . . : ......:...:: .:: :: ....::.::::
CCDS44 KN-TFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKK
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 SNHLESKQSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNL
CCDS44 M
>>CCDS8898.1 CDK2 gene_id:1017|Hs108|chr12 (298 aa)
initn: 503 init1: 268 opt: 750 Z-score: 414.3 bits: 85.7 E(32554): 9.4e-17
Smith-Waterman score: 750; 39.3% identity (71.7% similar) in 290 aa overlap (1-285:1-287)
10 20 30 40 50
pF1KE0 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWD-ECMNLREVKSLKKLNH
:. . ....:.:::: : .... .::.::.:... . .::.. ::.:::
CCDS88 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 ANVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKL--FPESVIRNIMYQILQGLAFIH
:..:: .::. ...::..::.....: ..: : . : .: .:.. ..:.:::::: :
CCDS88 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFM-DASALTGIPLPLIKSYLFQLLQGLAFCH
70 80 90 100 110
120 130 140 150 160 170
pF1KE0 KHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQP--PYTDYVSTRWYRAPEVLLRSS
.: .:::.::.::: .:.::::::: . . : :: : : ::::::.:: .
CCDS88 SHRVLHRDLKPQNLLINTEGAIKLADFGLARAF-GVPVRTYTHEVVTLWYRAPEILLGCK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 VYSSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMN
::. .:.:..: :.::. : :::: ::.:..:.: ..:::: . :: : ...
CCDS88 YYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWP-GVTSMPDYK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 FRFPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSN
::. . ... ..: .... .:...::..::.:: .:. :: ::.::
CCDS88 PSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLR
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 HLESKQSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSV
CCDS88 L
>>CCDS11736.1 CDK3 gene_id:1018|Hs108|chr17 (305 aa)
initn: 511 init1: 280 opt: 743 Z-score: 410.5 bits: 85.1 E(32554): 1.5e-16
Smith-Waterman score: 743; 38.5% identity (72.2% similar) in 288 aa overlap (1-284:1-286)
10 20 30 40 50
pF1KE0 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWD-ECMNLREVKSLKKLNH
:. . ....:.:::: : .:. :.:.:::.:... . .::.. ::.:.:
CCDS11 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 ANVIKLKEVIRENDHLYFIFEYMKENLYQLMKDR-NKLFPESVIRNIMYQILQGLAFIHK
:...: .:.... .::..::.....: . : . .. .: .:.. ..:.:::..: :.
CCDS11 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 HGFFHRDMKPENLLCMGPELVKIADFGLARELRSQP--PYTDYVSTRWYRAPEVLLRSSV
: .:::.::.::: .:.::::::: . . : :: : : ::::::.:: :.
CCDS11 HRVIHRDLKPQNLLINELGAIKLADFGLARAF-GVPLRTYTHEVVTLWYRAPEILLGSKF
130 140 150 160 170
180 190 200 210 220 230
pF1KE0 YSSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNF
:.. .:.:..: :.::. . :::: ::.:..:.: ..::::... :: :: . ..
CCDS11 YTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPD-YKG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 RFPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNH
::. . .:. ..:: :. .:. ..:..::..: ::. :: ::::
CCDS11 SFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEPSPAARQY
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 LESKQSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQ
CCDS11 VLQRFRH
300
>>CCDS9061.1 CDK17 gene_id:5128|Hs108|chr12 (523 aa)
initn: 733 init1: 387 opt: 745 Z-score: 408.6 bits: 85.5 E(32554): 1.9e-16
Smith-Waterman score: 745; 38.8% identity (67.5% similar) in 320 aa overlap (1-316:189-503)
10 20 30
pF1KE0 MNRYTTMRQLGDGTYGSVLMGKSNESGELV
:. : ...::.:::..: :.:. . .::
CCDS90 EKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLV
160 170 180 190 200 210
40 50 60 70 80 90
pF1KE0 AIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENDHLYFIFEYMKENLYQLM
:.:... . : .:::. :: :.:::.. :..... . : ..:::. ..: : :
CCDS90 ALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYM
220 230 240 250 260 270
100 110 120 130 140 150
pF1KE0 KDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLAREL
: .... .. ..::::.:::. :.. .:::.::.::: .:.:::::::
CCDS90 DDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARA-
280 290 300 310 320 330
160 170 180 190 200
pF1KE0 RSQPP--YTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYMLRPLFPGTSEVDE
.: : :.. : : ::: :.::: :: ::. ::.:.:: :. :. ::::::.. ::
CCDS90 KSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDE
340 350 360 370 380 390
210 220 230 240 250 260
pF1KE0 IFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCVPINLKTLIPNASNEAIQLMTEMLNWD
. : ..::::.. :: . :. ::. : : . : ..:.:.:.:..:...
CCDS90 LHLIFRLLGTPSQETWPGISSNEEFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQYE
400 410 420 430 440 450
270 280 290 300 310 320
pF1KE0 PKKRPTASQALKHPYFQVGQVLGPSSNHLESKQSLN--KQLQPLESKPSLVEVEPKPLPD
::: .: .:.:: ::. ::: . : . :. :..: :.. :..
CCDS90 SKKRVSAEEAMKHVYFRS---LGPRIHALPESVSIFSLKEIQ-LQKDPGFRNSSYPETGH
460 470 480 490 500 510
330 340 350 360 370 380
pF1KE0 IIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPKQQSQEKPPQTLFPSIVKNMPTKPNGT
CCDS90 GKNRRQSMLF
520
623 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:04:00 2016 done: Sat Nov 5 18:04:01 2016
Total Scan time: 3.860 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]