FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0989, 623 aa 1>>>pF1KE0989 623 - 623 aa - 623 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 16.5634+/-0.00061; mu= -36.7472+/- 0.038 mean_var=705.9205+/-151.662, 0's: 0 Z-trim(118.6): 1388 B-trim: 873 in 1/57 Lambda= 0.048272 statistics sampled from 29978 (31767) to 29978 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.372), width: 16 Scan time: 11.640 The best scores are: opt bits E(85289) NP_005897 (OMIM: 154235,614181) serine/threonine-p ( 623) 4217 309.6 2e-83 XP_016866353 (OMIM: 154235,614181) PREDICTED: seri ( 623) 4217 309.6 2e-83 NP_001229314 (OMIM: 154235,614181) serine/threonin ( 583) 3602 266.8 1.5e-70 XP_011512924 (OMIM: 154235,614181) PREDICTED: seri ( 583) 3602 266.8 1.5e-70 XP_011512921 (OMIM: 154235,614181) PREDICTED: seri ( 648) 3600 266.7 1.8e-70 XP_016866352 (OMIM: 154235,614181) PREDICTED: seri ( 648) 3600 266.7 1.8e-70 NP_001229886 (OMIM: 154235,614181) serine/threonin ( 648) 3600 266.7 1.8e-70 XP_011512922 (OMIM: 154235,614181) PREDICTED: seri ( 648) 3600 266.7 1.8e-70 XP_016866354 (OMIM: 154235,614181) PREDICTED: seri ( 564) 3393 252.2 3.5e-66 XP_011512923 (OMIM: 154235,614181) PREDICTED: seri ( 629) 3391 252.1 4.3e-66 XP_016866355 (OMIM: 154235,614181) PREDICTED: seri ( 439) 2993 224.3 7e-58 XP_016865977 (OMIM: 612325,612651) PREDICTED: seri ( 632) 1916 149.4 3.6e-35 XP_016865979 (OMIM: 612325,612651) PREDICTED: seri ( 632) 1916 149.4 3.6e-35 XP_016865978 (OMIM: 612325,612651) PREDICTED: seri ( 632) 1916 149.4 3.6e-35 XP_016865981 (OMIM: 612325,612651) PREDICTED: seri ( 632) 1916 149.4 3.6e-35 XP_016865980 (OMIM: 612325,612651) PREDICTED: seri ( 632) 1916 149.4 3.6e-35 NP_057597 (OMIM: 612325,612651) serine/threonine-p ( 632) 1916 149.4 3.6e-35 NP_055735 (OMIM: 612325,612651) serine/threonine-p ( 632) 1916 149.4 3.6e-35 XP_011512723 (OMIM: 612325,612651) PREDICTED: seri ( 639) 1892 147.7 1.1e-34 XP_016865976 (OMIM: 612325,612651) PREDICTED: seri ( 639) 1892 147.7 1.1e-34 XP_016865975 (OMIM: 612325,612651) PREDICTED: seri ( 639) 1892 147.7 1.1e-34 XP_011512722 (OMIM: 612325,612651) PREDICTED: seri ( 639) 1892 147.7 1.1e-34 XP_011512721 (OMIM: 612325,612651) PREDICTED: seri ( 639) 1892 147.7 1.1e-34 XP_016865974 (OMIM: 612325,612651) PREDICTED: seri ( 639) 1892 147.7 1.1e-34 XP_011512926 (OMIM: 154235,614181) PREDICTED: seri ( 388) 1848 144.5 6.4e-34 XP_006720288 (OMIM: 605762) PREDICTED: MAPK/MAK/MR ( 293) 767 69.2 2.4e-11 XP_016877044 (OMIM: 605762) PREDICTED: MAPK/MAK/MR ( 292) 763 68.9 2.9e-11 XP_006720289 (OMIM: 605762) PREDICTED: MAPK/MAK/MR ( 292) 761 68.7 3.1e-11 XP_011535354 (OMIM: 605762) PREDICTED: MAPK/MAK/MR ( 356) 761 68.8 3.7e-11 NP_055041 (OMIM: 605762) MAPK/MAK/MRK overlapping ( 419) 761 68.8 4.2e-11 XP_005270360 (OMIM: 116940) PREDICTED: cyclin-depe ( 297) 753 68.2 4.7e-11 NP_001307847 (OMIM: 116940) cyclin-dependent kinas ( 297) 753 68.2 4.7e-11 NP_001777 (OMIM: 116940) cyclin-dependent kinase 1 ( 297) 753 68.2 4.7e-11 NP_001317163 (OMIM: 605762) MAPK/MAK/MRK overlappi ( 418) 757 68.6 5.1e-11 NP_001789 (OMIM: 116953) cyclin-dependent kinase 2 ( 298) 750 68.0 5.4e-11 NP_001249 (OMIM: 123828) cyclin-dependent kinase 3 ( 305) 743 67.5 7.8e-11 XP_016874895 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 745 67.8 1.1e-10 XP_016874894 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 745 67.8 1.1e-10 NP_002586 (OMIM: 603440) cyclin-dependent kinase 1 ( 523) 745 67.8 1.1e-10 NP_001163935 (OMIM: 603440) cyclin-dependent kinas ( 523) 745 67.8 1.1e-10 NP_997667 (OMIM: 169190) cyclin-dependent kinase 1 ( 474) 700 64.6 8.8e-10 NP_002587 (OMIM: 169190) cyclin-dependent kinase 1 ( 474) 700 64.6 8.8e-10 NP_997668 (OMIM: 169190) cyclin-dependent kinase 1 ( 504) 700 64.6 9.3e-10 XP_011507904 (OMIM: 169190) PREDICTED: cyclin-depe ( 542) 700 64.7 9.8e-10 XP_016856912 (OMIM: 169190) PREDICTED: cyclin-depe ( 572) 700 64.7 1e-09 NP_004187 (OMIM: 603441) cyclin-dependent kinase-l ( 358) 689 63.8 1.2e-09 XP_016877218 (OMIM: 603441) PREDICTED: cyclin-depe ( 358) 689 63.8 1.2e-09 XP_005268214 (OMIM: 603441) PREDICTED: cyclin-depe ( 358) 689 63.8 1.2e-09 XP_011542227 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 680 63.3 2.4e-09 XP_011542230 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 680 63.3 2.4e-09 >>NP_005897 (OMIM: 154235,614181) serine/threonine-prote (623 aa) initn: 4217 init1: 4217 opt: 4217 Z-score: 1618.6 bits: 309.6 E(85289): 2e-83 Smith-Waterman score: 4217; 100.0% identity (100.0% similar) in 623 aa overlap (1-623:1-623) 10 20 30 40 50 60 pF1KE0 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 QSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 QQSQEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QQSQEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 KKPSMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 KKPSMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 LKQSRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNAGNLGSYAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LKQSRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNAGNLGSYAT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 YNQSGYIPSFLKKEVQSAGQRIHLAPLNATASEYTWNTKTGRGQFSGRTYNPTAKNLNIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 YNQSGYIPSFLKKEVQSAGQRIHLAPLNATASEYTWNTKTGRGQFSGRTYNPTAKNLNIV 550 560 570 580 590 600 610 620 pF1KE0 NRAQPIPSVHGRTDWVAKYGGHR ::::::::::::::::::::::: NP_005 NRAQPIPSVHGRTDWVAKYGGHR 610 620 >>XP_016866353 (OMIM: 154235,614181) PREDICTED: serine/t (623 aa) initn: 4217 init1: 4217 opt: 4217 Z-score: 1618.6 bits: 309.6 E(85289): 2e-83 Smith-Waterman score: 4217; 100.0% identity (100.0% similar) in 623 aa overlap (1-623:1-623) 10 20 30 40 50 60 pF1KE0 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 QSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 QQSQEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQSQEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 KKPSMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKPSMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 LKQSRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNAGNLGSYAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKQSRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNAGNLGSYAT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 YNQSGYIPSFLKKEVQSAGQRIHLAPLNATASEYTWNTKTGRGQFSGRTYNPTAKNLNIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YNQSGYIPSFLKKEVQSAGQRIHLAPLNATASEYTWNTKTGRGQFSGRTYNPTAKNLNIV 550 560 570 580 590 600 610 620 pF1KE0 NRAQPIPSVHGRTDWVAKYGGHR ::::::::::::::::::::::: XP_016 NRAQPIPSVHGRTDWVAKYGGHR 610 620 >>NP_001229314 (OMIM: 154235,614181) serine/threonine-pr (583 aa) initn: 3600 init1: 3600 opt: 3602 Z-score: 1387.5 bits: 266.8 E(85289): 1.5e-70 Smith-Waterman score: 3871; 93.6% identity (93.6% similar) in 623 aa overlap (1-623:1-583) 10 20 30 40 50 60 pF1KE0 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 QSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 QQSQEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQSQEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 KKPSMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKPSMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 LKQSRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNAGNLGSYAT :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKQSRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNA-------- 490 500 510 520 530 550 560 570 580 590 600 pF1KE0 YNQSGYIPSFLKKEVQSAGQRIHLAPLNATASEYTWNTKTGRGQFSGRTYNPTAKNLNIV :::::::::::::::::::::::::::: NP_001 --------------------------------EYTWNTKTGRGQFSGRTYNPTAKNLNIV 540 550 560 610 620 pF1KE0 NRAQPIPSVHGRTDWVAKYGGHR ::::::::::::::::::::::: NP_001 NRAQPIPSVHGRTDWVAKYGGHR 570 580 >>XP_011512924 (OMIM: 154235,614181) PREDICTED: serine/t (583 aa) initn: 3600 init1: 3600 opt: 3602 Z-score: 1387.5 bits: 266.8 E(85289): 1.5e-70 Smith-Waterman score: 3871; 93.6% identity (93.6% similar) in 623 aa overlap (1-623:1-583) 10 20 30 40 50 60 pF1KE0 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 QSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 QQSQEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQSQEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 KKPSMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKPSMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 LKQSRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNAGNLGSYAT :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKQSRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNA-------- 490 500 510 520 530 550 560 570 580 590 600 pF1KE0 YNQSGYIPSFLKKEVQSAGQRIHLAPLNATASEYTWNTKTGRGQFSGRTYNPTAKNLNIV :::::::::::::::::::::::::::: XP_011 --------------------------------EYTWNTKTGRGQFSGRTYNPTAKNLNIV 540 550 560 610 620 pF1KE0 NRAQPIPSVHGRTDWVAKYGGHR ::::::::::::::::::::::: XP_011 NRAQPIPSVHGRTDWVAKYGGHR 570 580 >>XP_011512921 (OMIM: 154235,614181) PREDICTED: serine/t (648 aa) initn: 4203 init1: 3600 opt: 3600 Z-score: 1386.1 bits: 266.7 E(85289): 1.8e-70 Smith-Waterman score: 4157; 96.1% identity (96.1% similar) in 648 aa overlap (1-623:1-648) 10 20 30 40 50 60 pF1KE0 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 QSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 QQSQEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQSQEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 KKPSMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKPSMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYY 430 440 450 460 470 480 490 500 510 520 530 pF1KE0 LKQSRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNA-------- :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKQSRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNAEESIIKPI 490 500 510 520 530 540 540 550 560 570 pF1KE0 -----------------GNLGSYATYNQSGYIPSFLKKEVQSAGQRIHLAPLNATASEYT ::::::::::::::::::::::::::::::::::::::::::: XP_011 EKLSCNETFPEKLEDPQGNLGSYATYNQSGYIPSFLKKEVQSAGQRIHLAPLNATASEYT 550 560 570 580 590 600 580 590 600 610 620 pF1KE0 WNTKTGRGQFSGRTYNPTAKNLNIVNRAQPIPSVHGRTDWVAKYGGHR :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WNTKTGRGQFSGRTYNPTAKNLNIVNRAQPIPSVHGRTDWVAKYGGHR 610 620 630 640 >>XP_016866352 (OMIM: 154235,614181) PREDICTED: serine/t (648 aa) initn: 4203 init1: 3600 opt: 3600 Z-score: 1386.1 bits: 266.7 E(85289): 1.8e-70 Smith-Waterman score: 4157; 96.1% identity (96.1% similar) in 648 aa overlap (1-623:1-648) 10 20 30 40 50 60 pF1KE0 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 QSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 QQSQEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQSQEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 KKPSMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKPSMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYY 430 440 450 460 470 480 490 500 510 520 530 pF1KE0 LKQSRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNA-------- :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKQSRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNAEESIIKPI 490 500 510 520 530 540 540 550 560 570 pF1KE0 -----------------GNLGSYATYNQSGYIPSFLKKEVQSAGQRIHLAPLNATASEYT ::::::::::::::::::::::::::::::::::::::::::: XP_016 EKLSCNETFPEKLEDPQGNLGSYATYNQSGYIPSFLKKEVQSAGQRIHLAPLNATASEYT 550 560 570 580 590 600 580 590 600 610 620 pF1KE0 WNTKTGRGQFSGRTYNPTAKNLNIVNRAQPIPSVHGRTDWVAKYGGHR :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WNTKTGRGQFSGRTYNPTAKNLNIVNRAQPIPSVHGRTDWVAKYGGHR 610 620 630 640 >>NP_001229886 (OMIM: 154235,614181) serine/threonine-pr (648 aa) initn: 4203 init1: 3600 opt: 3600 Z-score: 1386.1 bits: 266.7 E(85289): 1.8e-70 Smith-Waterman score: 4157; 96.1% identity (96.1% similar) in 648 aa overlap (1-623:1-648) 10 20 30 40 50 60 pF1KE0 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 QSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 QQSQEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQSQEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 KKPSMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKPSMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYY 430 440 450 460 470 480 490 500 510 520 530 pF1KE0 LKQSRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNA-------- :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKQSRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNAEESIIKPI 490 500 510 520 530 540 540 550 560 570 pF1KE0 -----------------GNLGSYATYNQSGYIPSFLKKEVQSAGQRIHLAPLNATASEYT ::::::::::::::::::::::::::::::::::::::::::: NP_001 EKLSCNETFPEKLEDPQGNLGSYATYNQSGYIPSFLKKEVQSAGQRIHLAPLNATASEYT 550 560 570 580 590 600 580 590 600 610 620 pF1KE0 WNTKTGRGQFSGRTYNPTAKNLNIVNRAQPIPSVHGRTDWVAKYGGHR :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WNTKTGRGQFSGRTYNPTAKNLNIVNRAQPIPSVHGRTDWVAKYGGHR 610 620 630 640 >>XP_011512922 (OMIM: 154235,614181) PREDICTED: serine/t (648 aa) initn: 4203 init1: 3600 opt: 3600 Z-score: 1386.1 bits: 266.7 E(85289): 1.8e-70 Smith-Waterman score: 4157; 96.1% identity (96.1% similar) in 648 aa overlap (1-623:1-648) 10 20 30 40 50 60 pF1KE0 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 QSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 QQSQEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQSQEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 KKPSMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKPSMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYY 430 440 450 460 470 480 490 500 510 520 530 pF1KE0 LKQSRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNA-------- :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKQSRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNAEESIIKPI 490 500 510 520 530 540 540 550 560 570 pF1KE0 -----------------GNLGSYATYNQSGYIPSFLKKEVQSAGQRIHLAPLNATASEYT ::::::::::::::::::::::::::::::::::::::::::: XP_011 EKLSCNETFPEKLEDPQGNLGSYATYNQSGYIPSFLKKEVQSAGQRIHLAPLNATASEYT 550 560 570 580 590 600 580 590 600 610 620 pF1KE0 WNTKTGRGQFSGRTYNPTAKNLNIVNRAQPIPSVHGRTDWVAKYGGHR :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WNTKTGRGQFSGRTYNPTAKNLNIVNRAQPIPSVHGRTDWVAKYGGHR 610 620 630 640 >>XP_016866354 (OMIM: 154235,614181) PREDICTED: serine/t (564 aa) initn: 3391 init1: 3391 opt: 3393 Z-score: 1309.1 bits: 252.2 E(85289): 3.5e-66 Smith-Waterman score: 3662; 93.2% identity (93.2% similar) in 590 aa overlap (34-623:15-564) 10 20 30 40 50 60 pF1KE0 YTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVI :::::::::::::::::::::::::::::: XP_016 MKHTRRRSFTRERTRMKRKFYSWDECMNLREVKSLKKLNHANVI 10 20 30 40 70 80 90 100 110 120 pF1KE0 KLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFH 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 RDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDV 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE0 WAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCVP 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE0 INLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESKQSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 INLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESKQSL 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE0 NKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPKQQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPKQQS 290 300 310 320 330 340 370 380 390 400 410 420 pF1KE0 QEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHSKKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHSKKP 350 360 370 380 390 400 430 440 450 460 470 480 pF1KE0 SMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYYLKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYYLKQ 410 420 430 440 450 460 490 500 510 520 530 540 pF1KE0 SRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNAGNLGSYATYNQ ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNA----------- 470 480 490 500 510 550 560 570 580 590 600 pF1KE0 SGYIPSFLKKEVQSAGQRIHLAPLNATASEYTWNTKTGRGQFSGRTYNPTAKNLNIVNRA ::::::::::::::::::::::::::::::: XP_016 -----------------------------EYTWNTKTGRGQFSGRTYNPTAKNLNIVNRA 520 530 540 610 620 pF1KE0 QPIPSVHGRTDWVAKYGGHR :::::::::::::::::::: XP_016 QPIPSVHGRTDWVAKYGGHR 550 560 >>XP_011512923 (OMIM: 154235,614181) PREDICTED: serine/t (629 aa) initn: 3994 init1: 3391 opt: 3391 Z-score: 1307.6 bits: 252.1 E(85289): 4.3e-66 Smith-Waterman score: 3948; 95.9% identity (95.9% similar) in 615 aa overlap (34-623:15-629) 10 20 30 40 50 60 pF1KE0 YTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVI :::::::::::::::::::::::::::::: XP_011 MKHTRRRSFTRERTRMKRKFYSWDECMNLREVKSLKKLNHANVI 10 20 30 40 70 80 90 100 110 120 pF1KE0 KLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFH 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 RDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDV 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE0 WAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCVP 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE0 INLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESKQSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 INLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESKQSL 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE0 NKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPKQQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPKQQS 290 300 310 320 330 340 370 380 390 400 410 420 pF1KE0 QEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHSKKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHSKKP 350 360 370 380 390 400 430 440 450 460 470 480 pF1KE0 SMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYYLKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYYLKQ 410 420 430 440 450 460 490 500 510 520 530 pF1KE0 SRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNA----------- ::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNAEESIIKPIEKL 470 480 490 500 510 520 540 550 560 570 pF1KE0 --------------GNLGSYATYNQSGYIPSFLKKEVQSAGQRIHLAPLNATASEYTWNT :::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCNETFPEKLEDPQGNLGSYATYNQSGYIPSFLKKEVQSAGQRIHLAPLNATASEYTWNT 530 540 550 560 570 580 580 590 600 610 620 pF1KE0 KTGRGQFSGRTYNPTAKNLNIVNRAQPIPSVHGRTDWVAKYGGHR ::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTGRGQFSGRTYNPTAKNLNIVNRAQPIPSVHGRTDWVAKYGGHR 590 600 610 620 623 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 18:04:01 2016 done: Sat Nov 5 18:04:03 2016 Total Scan time: 11.640 Total Display time: 0.160 Function used was FASTA [36.3.4 Apr, 2011]