FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0993, 645 aa 1>>>pF1KE0993 645 - 645 aa - 645 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.8217+/-0.000651; mu= -4.8649+/- 0.040 mean_var=593.4779+/-131.769, 0's: 0 Z-trim(116.5): 1894 B-trim: 557 in 1/52 Lambda= 0.052647 statistics sampled from 25319 (27796) to 25319 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.664), E-opt: 0.2 (0.326), width: 16 Scan time: 10.100 The best scores are: opt bits E(85289) XP_011511469 (OMIM: 609779) PREDICTED: serine/thre ( 645) 4242 338.4 4.9e-92 NP_001308149 (OMIM: 609779) serine/threonine-prote ( 645) 4242 338.4 4.9e-92 NP_079076 (OMIM: 609779) serine/threonine-protein ( 645) 4242 338.4 4.9e-92 XP_016862703 (OMIM: 609779) PREDICTED: serine/thre ( 599) 3566 287.0 1.4e-76 NP_001139475 (OMIM: 609779) serine/threonine-prote ( 599) 3566 287.0 1.4e-76 XP_016862702 (OMIM: 609779) PREDICTED: serine/thre ( 599) 3566 287.0 1.4e-76 XP_016862708 (OMIM: 609779) PREDICTED: serine/thre ( 539) 3531 284.2 8e-76 XP_016862707 (OMIM: 609779) PREDICTED: serine/thre ( 539) 3531 284.2 8e-76 XP_016862698 (OMIM: 609779) PREDICTED: serine/thre ( 687) 3532 284.5 8.7e-76 XP_016862697 (OMIM: 609779) PREDICTED: serine/thre ( 687) 3532 284.5 8.7e-76 XP_016862699 (OMIM: 609779) PREDICTED: serine/thre ( 687) 3532 284.5 8.7e-76 XP_016862694 (OMIM: 609779) PREDICTED: serine/thre ( 687) 3532 284.5 8.7e-76 XP_016862696 (OMIM: 609779) PREDICTED: serine/thre ( 687) 3532 284.5 8.7e-76 XP_016862695 (OMIM: 609779) PREDICTED: serine/thre ( 687) 3532 284.5 8.7e-76 NP_001308150 (OMIM: 609779) serine/threonine-prote ( 687) 3532 284.5 8.7e-76 XP_016862713 (OMIM: 609779) PREDICTED: serine/thre ( 497) 3284 265.4 3.4e-70 XP_016862715 (OMIM: 609779) PREDICTED: serine/thre ( 497) 3284 265.4 3.4e-70 XP_016862717 (OMIM: 609779) PREDICTED: serine/thre ( 497) 3284 265.4 3.4e-70 XP_011511477 (OMIM: 609779) PREDICTED: serine/thre ( 497) 3284 265.4 3.4e-70 XP_011511475 (OMIM: 609779) PREDICTED: serine/thre ( 497) 3284 265.4 3.4e-70 XP_016862716 (OMIM: 609779) PREDICTED: serine/thre ( 497) 3284 265.4 3.4e-70 XP_011511476 (OMIM: 609779) PREDICTED: serine/thre ( 497) 3284 265.4 3.4e-70 XP_016862714 (OMIM: 609779) PREDICTED: serine/thre ( 497) 3284 265.4 3.4e-70 NP_665917 (OMIM: 609779) serine/threonine-protein ( 470) 3067 248.9 3e-65 NP_001308152 (OMIM: 609779) serine/threonine-prote ( 482) 3067 248.9 3.1e-65 XP_011511483 (OMIM: 609779) PREDICTED: serine/thre ( 463) 3065 248.8 3.3e-65 XP_016862700 (OMIM: 609779) PREDICTED: serine/thre ( 641) 2856 233.1 2.4e-60 XP_016862721 (OMIM: 609779) PREDICTED: serine/thre ( 451) 2608 214.0 9.2e-55 XP_016862722 (OMIM: 609779) PREDICTED: serine/thre ( 451) 2608 214.0 9.2e-55 XP_016862704 (OMIM: 609779) PREDICTED: serine/thre ( 563) 2581 212.1 4.3e-54 XP_016862705 (OMIM: 609779) PREDICTED: serine/thre ( 563) 2581 212.1 4.3e-54 XP_016862701 (OMIM: 609779) PREDICTED: serine/thre ( 609) 2581 212.2 4.5e-54 XP_016862711 (OMIM: 609779) PREDICTED: serine/thre ( 512) 2357 195.0 5.4e-49 XP_016862710 (OMIM: 609779) PREDICTED: serine/thre ( 524) 2357 195.1 5.5e-49 XP_016862709 (OMIM: 609779) PREDICTED: serine/thre ( 526) 2357 195.1 5.5e-49 XP_016862706 (OMIM: 609779) PREDICTED: serine/thre ( 540) 2125 177.5 1.1e-43 NP_001308151 (OMIM: 609779) serine/threonine-prote ( 540) 2125 177.5 1.1e-43 XP_016862720 (OMIM: 609779) PREDICTED: serine/thre ( 461) 1623 139.2 3.1e-32 NP_001308153 (OMIM: 609779) serine/threonine-prote ( 461) 1623 139.2 3.1e-32 XP_016862719 (OMIM: 609779) PREDICTED: serine/thre ( 494) 1449 126.1 3.1e-28 XP_016862718 (OMIM: 609779) PREDICTED: serine/thre ( 494) 1449 126.1 3.1e-28 XP_016862712 (OMIM: 609779) PREDICTED: serine/thre ( 504) 1444 125.7 4e-28 XP_006713373 (OMIM: 601959) PREDICTED: serine/thre ( 795) 790 76.3 4.7e-13 XP_011532342 (OMIM: 601959) PREDICTED: serine/thre ( 671) 788 76.0 4.7e-13 XP_016862575 (OMIM: 601959) PREDICTED: serine/thre ( 824) 790 76.3 4.8e-13 NP_003148 (OMIM: 601959) serine/threonine-protein ( 841) 788 76.2 5.4e-13 XP_011532341 (OMIM: 601959) PREDICTED: serine/thre ( 842) 788 76.2 5.4e-13 XP_016862574 (OMIM: 601959) PREDICTED: serine/thre ( 870) 788 76.2 5.5e-13 NP_001139571 (OMIM: 604044) serine/threonine-prote ( 489) 750 73.0 2.9e-12 NP_689933 (OMIM: 604044) serine/threonine-protein ( 506) 750 73.0 3e-12 >>XP_011511469 (OMIM: 609779) PREDICTED: serine/threonin (645 aa) initn: 4242 init1: 4242 opt: 4242 Z-score: 1773.3 bits: 338.4 E(85289): 4.9e-92 Smith-Waterman score: 4242; 100.0% identity (100.0% similar) in 645 aa overlap (1-645:1-645) 10 20 30 40 50 60 pF1KE0 MLKFQEAAKCVSGSTAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLKFQEAAKCVSGSTAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 QEYKQAGKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNVFLKNNLLKIGDFGVSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QEYKQAGKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNVFLKNNLLKIGDFGVSR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 VLKIVEGDTPSLPERYPKELNAIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLKIVEGDTPSLPERYPKELNAIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 MTLEDKNLDCQKEAAHIINAMQKRIHLQTLRALSEVQKMTPRERMRLRKLQAADEKARKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTLEDKNLDCQKEAAHIINAMQKRIHLQTLRALSEVQKMTPRERMRLRKLQAADEKARKL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 KKIVEEKYEENSKRMQELRSRNFQQLSVDVLHEKTHLKGMEEKEEQPEGRLSCSPQDEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKIVEEKYEENSKRMQELRSRNFQQLSVDVLHEKTHLKGMEEKEEQPEGRLSCSPQDEDE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 ERWQGREEESDEPTLENLPESQPIPSMDLHELESIVEDATSDLGYHEIPEDPLVAEEYYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERWQGREEESDEPTLENLPESQPIPSMDLHELESIVEDATSDLGYHEIPEDPLVAEEYYA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 DAFDSYCEESDEEEEEIALERPEKEIRNEGSQPAYRTNQQDSDIEALARCLENVLGCTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DAFDSYCEESDEEEEEIALERPEKEIRNEGSQPAYRTNQQDSDIEALARCLENVLGCTSL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 DTKTITTMAEDMSPGPPIFNSVMARTKMKRMRESAMQKLGTEVFEEVYNYLKRARHQNAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTKTITTMAEDMSPGPPIFNSVMARTKMKRMRESAMQKLGTEVFEEVYNYLKRARHQNAS 550 560 570 580 590 600 610 620 630 640 pF1KE0 EAEIRECLEKVVPQASDCFEVDQLLYFEEQLLITMGKEPTLQNHL ::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAEIRECLEKVVPQASDCFEVDQLLYFEEQLLITMGKEPTLQNHL 610 620 630 640 >>NP_001308149 (OMIM: 609779) serine/threonine-protein k (645 aa) initn: 4242 init1: 4242 opt: 4242 Z-score: 1773.3 bits: 338.4 E(85289): 4.9e-92 Smith-Waterman score: 4242; 100.0% identity (100.0% similar) in 645 aa overlap (1-645:1-645) 10 20 30 40 50 60 pF1KE0 MLKFQEAAKCVSGSTAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLKFQEAAKCVSGSTAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 QEYKQAGKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNVFLKNNLLKIGDFGVSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEYKQAGKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNVFLKNNLLKIGDFGVSR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 VLKIVEGDTPSLPERYPKELNAIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLKIVEGDTPSLPERYPKELNAIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 MTLEDKNLDCQKEAAHIINAMQKRIHLQTLRALSEVQKMTPRERMRLRKLQAADEKARKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTLEDKNLDCQKEAAHIINAMQKRIHLQTLRALSEVQKMTPRERMRLRKLQAADEKARKL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 KKIVEEKYEENSKRMQELRSRNFQQLSVDVLHEKTHLKGMEEKEEQPEGRLSCSPQDEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKIVEEKYEENSKRMQELRSRNFQQLSVDVLHEKTHLKGMEEKEEQPEGRLSCSPQDEDE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 ERWQGREEESDEPTLENLPESQPIPSMDLHELESIVEDATSDLGYHEIPEDPLVAEEYYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERWQGREEESDEPTLENLPESQPIPSMDLHELESIVEDATSDLGYHEIPEDPLVAEEYYA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 DAFDSYCEESDEEEEEIALERPEKEIRNEGSQPAYRTNQQDSDIEALARCLENVLGCTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DAFDSYCEESDEEEEEIALERPEKEIRNEGSQPAYRTNQQDSDIEALARCLENVLGCTSL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 DTKTITTMAEDMSPGPPIFNSVMARTKMKRMRESAMQKLGTEVFEEVYNYLKRARHQNAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DTKTITTMAEDMSPGPPIFNSVMARTKMKRMRESAMQKLGTEVFEEVYNYLKRARHQNAS 550 560 570 580 590 600 610 620 630 640 pF1KE0 EAEIRECLEKVVPQASDCFEVDQLLYFEEQLLITMGKEPTLQNHL ::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAEIRECLEKVVPQASDCFEVDQLLYFEEQLLITMGKEPTLQNHL 610 620 630 640 >>NP_079076 (OMIM: 609779) serine/threonine-protein kina (645 aa) initn: 4242 init1: 4242 opt: 4242 Z-score: 1773.3 bits: 338.4 E(85289): 4.9e-92 Smith-Waterman score: 4242; 100.0% identity (100.0% similar) in 645 aa overlap (1-645:1-645) 10 20 30 40 50 60 pF1KE0 MLKFQEAAKCVSGSTAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 MLKFQEAAKCVSGSTAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 KEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 QEYKQAGKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNVFLKNNLLKIGDFGVSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 QEYKQAGKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNVFLKNNLLKIGDFGVSR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 LLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 VLKIVEGDTPSLPERYPKELNAIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 VLKIVEGDTPSLPERYPKELNAIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 MTLEDKNLDCQKEAAHIINAMQKRIHLQTLRALSEVQKMTPRERMRLRKLQAADEKARKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 MTLEDKNLDCQKEAAHIINAMQKRIHLQTLRALSEVQKMTPRERMRLRKLQAADEKARKL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 KKIVEEKYEENSKRMQELRSRNFQQLSVDVLHEKTHLKGMEEKEEQPEGRLSCSPQDEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 KKIVEEKYEENSKRMQELRSRNFQQLSVDVLHEKTHLKGMEEKEEQPEGRLSCSPQDEDE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 ERWQGREEESDEPTLENLPESQPIPSMDLHELESIVEDATSDLGYHEIPEDPLVAEEYYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 ERWQGREEESDEPTLENLPESQPIPSMDLHELESIVEDATSDLGYHEIPEDPLVAEEYYA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 DAFDSYCEESDEEEEEIALERPEKEIRNEGSQPAYRTNQQDSDIEALARCLENVLGCTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 DAFDSYCEESDEEEEEIALERPEKEIRNEGSQPAYRTNQQDSDIEALARCLENVLGCTSL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 DTKTITTMAEDMSPGPPIFNSVMARTKMKRMRESAMQKLGTEVFEEVYNYLKRARHQNAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 DTKTITTMAEDMSPGPPIFNSVMARTKMKRMRESAMQKLGTEVFEEVYNYLKRARHQNAS 550 560 570 580 590 600 610 620 630 640 pF1KE0 EAEIRECLEKVVPQASDCFEVDQLLYFEEQLLITMGKEPTLQNHL ::::::::::::::::::::::::::::::::::::::::::::: NP_079 EAEIRECLEKVVPQASDCFEVDQLLYFEEQLLITMGKEPTLQNHL 610 620 630 640 >>XP_016862703 (OMIM: 609779) PREDICTED: serine/threonin (599 aa) initn: 3566 init1: 3566 opt: 3566 Z-score: 1496.1 bits: 287.0 E(85289): 1.4e-76 Smith-Waterman score: 3566; 100.0% identity (100.0% similar) in 541 aa overlap (1-541:1-541) 10 20 30 40 50 60 pF1KE0 MLKFQEAAKCVSGSTAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLKFQEAAKCVSGSTAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 QEYKQAGKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNVFLKNNLLKIGDFGVSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEYKQAGKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNVFLKNNLLKIGDFGVSR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 VLKIVEGDTPSLPERYPKELNAIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLKIVEGDTPSLPERYPKELNAIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 MTLEDKNLDCQKEAAHIINAMQKRIHLQTLRALSEVQKMTPRERMRLRKLQAADEKARKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTLEDKNLDCQKEAAHIINAMQKRIHLQTLRALSEVQKMTPRERMRLRKLQAADEKARKL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 KKIVEEKYEENSKRMQELRSRNFQQLSVDVLHEKTHLKGMEEKEEQPEGRLSCSPQDEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKIVEEKYEENSKRMQELRSRNFQQLSVDVLHEKTHLKGMEEKEEQPEGRLSCSPQDEDE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 ERWQGREEESDEPTLENLPESQPIPSMDLHELESIVEDATSDLGYHEIPEDPLVAEEYYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERWQGREEESDEPTLENLPESQPIPSMDLHELESIVEDATSDLGYHEIPEDPLVAEEYYA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 DAFDSYCEESDEEEEEIALERPEKEIRNEGSQPAYRTNQQDSDIEALARCLENVLGCTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DAFDSYCEESDEEEEEIALERPEKEIRNEGSQPAYRTNQQDSDIEALARCLENVLGCTSL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 DTKTITTMAEDMSPGPPIFNSVMARTKMKRMRESAMQKLGTEVFEEVYNYLKRARHQNAS : XP_016 DQPCRSWGQKYLKRSIITSREQGIRMLAKQRSASVWKKWCLKPATVLKWTSSCTLKSSC 550 560 570 580 590 >>NP_001139475 (OMIM: 609779) serine/threonine-protein k (599 aa) initn: 3566 init1: 3566 opt: 3566 Z-score: 1496.1 bits: 287.0 E(85289): 1.4e-76 Smith-Waterman score: 3566; 100.0% identity (100.0% similar) in 541 aa overlap (1-541:1-541) 10 20 30 40 50 60 pF1KE0 MLKFQEAAKCVSGSTAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLKFQEAAKCVSGSTAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 QEYKQAGKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNVFLKNNLLKIGDFGVSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEYKQAGKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNVFLKNNLLKIGDFGVSR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 VLKIVEGDTPSLPERYPKELNAIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLKIVEGDTPSLPERYPKELNAIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 MTLEDKNLDCQKEAAHIINAMQKRIHLQTLRALSEVQKMTPRERMRLRKLQAADEKARKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTLEDKNLDCQKEAAHIINAMQKRIHLQTLRALSEVQKMTPRERMRLRKLQAADEKARKL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 KKIVEEKYEENSKRMQELRSRNFQQLSVDVLHEKTHLKGMEEKEEQPEGRLSCSPQDEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKIVEEKYEENSKRMQELRSRNFQQLSVDVLHEKTHLKGMEEKEEQPEGRLSCSPQDEDE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 ERWQGREEESDEPTLENLPESQPIPSMDLHELESIVEDATSDLGYHEIPEDPLVAEEYYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERWQGREEESDEPTLENLPESQPIPSMDLHELESIVEDATSDLGYHEIPEDPLVAEEYYA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 DAFDSYCEESDEEEEEIALERPEKEIRNEGSQPAYRTNQQDSDIEALARCLENVLGCTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DAFDSYCEESDEEEEEIALERPEKEIRNEGSQPAYRTNQQDSDIEALARCLENVLGCTSL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 DTKTITTMAEDMSPGPPIFNSVMARTKMKRMRESAMQKLGTEVFEEVYNYLKRARHQNAS : NP_001 DQPCRSWGQKYLKRSIITSREQGIRMLAKQRSASVWKKWCLKPATVLKWTSSCTLKSSC 550 560 570 580 590 >>XP_016862702 (OMIM: 609779) PREDICTED: serine/threonin (599 aa) initn: 3566 init1: 3566 opt: 3566 Z-score: 1496.1 bits: 287.0 E(85289): 1.4e-76 Smith-Waterman score: 3566; 100.0% identity (100.0% similar) in 541 aa overlap (1-541:1-541) 10 20 30 40 50 60 pF1KE0 MLKFQEAAKCVSGSTAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLKFQEAAKCVSGSTAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 QEYKQAGKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNVFLKNNLLKIGDFGVSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEYKQAGKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNVFLKNNLLKIGDFGVSR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 VLKIVEGDTPSLPERYPKELNAIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLKIVEGDTPSLPERYPKELNAIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 MTLEDKNLDCQKEAAHIINAMQKRIHLQTLRALSEVQKMTPRERMRLRKLQAADEKARKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTLEDKNLDCQKEAAHIINAMQKRIHLQTLRALSEVQKMTPRERMRLRKLQAADEKARKL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 KKIVEEKYEENSKRMQELRSRNFQQLSVDVLHEKTHLKGMEEKEEQPEGRLSCSPQDEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKIVEEKYEENSKRMQELRSRNFQQLSVDVLHEKTHLKGMEEKEEQPEGRLSCSPQDEDE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 ERWQGREEESDEPTLENLPESQPIPSMDLHELESIVEDATSDLGYHEIPEDPLVAEEYYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERWQGREEESDEPTLENLPESQPIPSMDLHELESIVEDATSDLGYHEIPEDPLVAEEYYA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 DAFDSYCEESDEEEEEIALERPEKEIRNEGSQPAYRTNQQDSDIEALARCLENVLGCTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DAFDSYCEESDEEEEEIALERPEKEIRNEGSQPAYRTNQQDSDIEALARCLENVLGCTSL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 DTKTITTMAEDMSPGPPIFNSVMARTKMKRMRESAMQKLGTEVFEEVYNYLKRARHQNAS : XP_016 DQPCRSWGQKYLKRSIITSREQGIRMLAKQRSASVWKKWCLKPATVLKWTSSCTLKSSC 550 560 570 580 590 >>XP_016862708 (OMIM: 609779) PREDICTED: serine/threonin (539 aa) initn: 3531 init1: 3531 opt: 3531 Z-score: 1482.2 bits: 284.2 E(85289): 8e-76 Smith-Waterman score: 3531; 99.8% identity (100.0% similar) in 534 aa overlap (112-645:6-539) 90 100 110 120 130 140 pF1KE0 LLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKIQEYKQAGKIFPENQIIEWFIQ .::::::::::::::::::::::::::::: XP_016 MAILPKGRDLDDKIQEYKQAGKIFPENQIIEWFIQ 10 20 30 150 160 170 180 190 200 pF1KE0 LLLGVDYMHERRILHRDLKSKNVFLKNNLLKIGDFGVSRLLMGSCDLATTLTGTPHYMSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLLGVDYMHERRILHRDLKSKNVFLKNNLLKIGDFGVSRLLMGSCDLATTLTGTPHYMSP 40 50 60 70 80 90 210 220 230 240 250 260 pF1KE0 EALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSIVLKIVEGDTPSLPERYPKELN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSIVLKIVEGDTPSLPERYPKELN 100 110 120 130 140 150 270 280 290 300 310 320 pF1KE0 AIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSEMTLEDKNLDCQKEAAHIINAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSEMTLEDKNLDCQKEAAHIINAM 160 170 180 190 200 210 330 340 350 360 370 380 pF1KE0 QKRIHLQTLRALSEVQKMTPRERMRLRKLQAADEKARKLKKIVEEKYEENSKRMQELRSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKRIHLQTLRALSEVQKMTPRERMRLRKLQAADEKARKLKKIVEEKYEENSKRMQELRSR 220 230 240 250 260 270 390 400 410 420 430 440 pF1KE0 NFQQLSVDVLHEKTHLKGMEEKEEQPEGRLSCSPQDEDEERWQGREEESDEPTLENLPES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NFQQLSVDVLHEKTHLKGMEEKEEQPEGRLSCSPQDEDEERWQGREEESDEPTLENLPES 280 290 300 310 320 330 450 460 470 480 490 500 pF1KE0 QPIPSMDLHELESIVEDATSDLGYHEIPEDPLVAEEYYADAFDSYCEESDEEEEEIALER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPIPSMDLHELESIVEDATSDLGYHEIPEDPLVAEEYYADAFDSYCEESDEEEEEIALER 340 350 360 370 380 390 510 520 530 540 550 560 pF1KE0 PEKEIRNEGSQPAYRTNQQDSDIEALARCLENVLGCTSLDTKTITTMAEDMSPGPPIFNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEKEIRNEGSQPAYRTNQQDSDIEALARCLENVLGCTSLDTKTITTMAEDMSPGPPIFNS 400 410 420 430 440 450 570 580 590 600 610 620 pF1KE0 VMARTKMKRMRESAMQKLGTEVFEEVYNYLKRARHQNASEAEIRECLEKVVPQASDCFEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VMARTKMKRMRESAMQKLGTEVFEEVYNYLKRARHQNASEAEIRECLEKVVPQASDCFEV 460 470 480 490 500 510 630 640 pF1KE0 DQLLYFEEQLLITMGKEPTLQNHL :::::::::::::::::::::::: XP_016 DQLLYFEEQLLITMGKEPTLQNHL 520 530 >>XP_016862707 (OMIM: 609779) PREDICTED: serine/threonin (539 aa) initn: 3531 init1: 3531 opt: 3531 Z-score: 1482.2 bits: 284.2 E(85289): 8e-76 Smith-Waterman score: 3531; 99.8% identity (100.0% similar) in 534 aa overlap (112-645:6-539) 90 100 110 120 130 140 pF1KE0 LLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKIQEYKQAGKIFPENQIIEWFIQ .::::::::::::::::::::::::::::: XP_016 MAILPKGRDLDDKIQEYKQAGKIFPENQIIEWFIQ 10 20 30 150 160 170 180 190 200 pF1KE0 LLLGVDYMHERRILHRDLKSKNVFLKNNLLKIGDFGVSRLLMGSCDLATTLTGTPHYMSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLLGVDYMHERRILHRDLKSKNVFLKNNLLKIGDFGVSRLLMGSCDLATTLTGTPHYMSP 40 50 60 70 80 90 210 220 230 240 250 260 pF1KE0 EALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSIVLKIVEGDTPSLPERYPKELN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSIVLKIVEGDTPSLPERYPKELN 100 110 120 130 140 150 270 280 290 300 310 320 pF1KE0 AIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSEMTLEDKNLDCQKEAAHIINAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSEMTLEDKNLDCQKEAAHIINAM 160 170 180 190 200 210 330 340 350 360 370 380 pF1KE0 QKRIHLQTLRALSEVQKMTPRERMRLRKLQAADEKARKLKKIVEEKYEENSKRMQELRSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKRIHLQTLRALSEVQKMTPRERMRLRKLQAADEKARKLKKIVEEKYEENSKRMQELRSR 220 230 240 250 260 270 390 400 410 420 430 440 pF1KE0 NFQQLSVDVLHEKTHLKGMEEKEEQPEGRLSCSPQDEDEERWQGREEESDEPTLENLPES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NFQQLSVDVLHEKTHLKGMEEKEEQPEGRLSCSPQDEDEERWQGREEESDEPTLENLPES 280 290 300 310 320 330 450 460 470 480 490 500 pF1KE0 QPIPSMDLHELESIVEDATSDLGYHEIPEDPLVAEEYYADAFDSYCEESDEEEEEIALER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPIPSMDLHELESIVEDATSDLGYHEIPEDPLVAEEYYADAFDSYCEESDEEEEEIALER 340 350 360 370 380 390 510 520 530 540 550 560 pF1KE0 PEKEIRNEGSQPAYRTNQQDSDIEALARCLENVLGCTSLDTKTITTMAEDMSPGPPIFNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEKEIRNEGSQPAYRTNQQDSDIEALARCLENVLGCTSLDTKTITTMAEDMSPGPPIFNS 400 410 420 430 440 450 570 580 590 600 610 620 pF1KE0 VMARTKMKRMRESAMQKLGTEVFEEVYNYLKRARHQNASEAEIRECLEKVVPQASDCFEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VMARTKMKRMRESAMQKLGTEVFEEVYNYLKRARHQNASEAEIRECLEKVVPQASDCFEV 460 470 480 490 500 510 630 640 pF1KE0 DQLLYFEEQLLITMGKEPTLQNHL :::::::::::::::::::::::: XP_016 DQLLYFEEQLLITMGKEPTLQNHL 520 530 >>XP_016862698 (OMIM: 609779) PREDICTED: serine/threonin (687 aa) initn: 3531 init1: 3531 opt: 3532 Z-score: 1481.6 bits: 284.5 E(85289): 8.7e-76 Smith-Waterman score: 4080; 93.8% identity (93.8% similar) in 677 aa overlap (11-645:11-687) 10 20 30 40 50 60 pF1KE0 MLKFQEAAKCVSGSTAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVL :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLKFQEAAKCVSGSTAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVL 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 KEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCE-------- :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEDLSKENCK 70 80 90 100 110 120 120 130 pF1KE0 ----------------------------------GRDLDDKIQEYKQAGKIFPENQIIEW :::::::::::::::::::::::::: XP_016 PLLNEIKEDTNKWKNIPCSWVGRINIVKMAILPKGRDLDDKIQEYKQAGKIFPENQIIEW 130 140 150 160 170 180 140 150 160 170 180 190 pF1KE0 FIQLLLGVDYMHERRILHRDLKSKNVFLKNNLLKIGDFGVSRLLMGSCDLATTLTGTPHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FIQLLLGVDYMHERRILHRDLKSKNVFLKNNLLKIGDFGVSRLLMGSCDLATTLTGTPHY 190 200 210 220 230 240 200 210 220 230 240 250 pF1KE0 MSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSIVLKIVEGDTPSLPERYPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSIVLKIVEGDTPSLPERYPK 250 260 270 280 290 300 260 270 280 290 300 310 pF1KE0 ELNAIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSEMTLEDKNLDCQKEAAHII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELNAIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSEMTLEDKNLDCQKEAAHII 310 320 330 340 350 360 320 330 340 350 360 370 pF1KE0 NAMQKRIHLQTLRALSEVQKMTPRERMRLRKLQAADEKARKLKKIVEEKYEENSKRMQEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NAMQKRIHLQTLRALSEVQKMTPRERMRLRKLQAADEKARKLKKIVEEKYEENSKRMQEL 370 380 390 400 410 420 380 390 400 410 420 430 pF1KE0 RSRNFQQLSVDVLHEKTHLKGMEEKEEQPEGRLSCSPQDEDEERWQGREEESDEPTLENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSRNFQQLSVDVLHEKTHLKGMEEKEEQPEGRLSCSPQDEDEERWQGREEESDEPTLENL 430 440 450 460 470 480 440 450 460 470 480 490 pF1KE0 PESQPIPSMDLHELESIVEDATSDLGYHEIPEDPLVAEEYYADAFDSYCEESDEEEEEIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PESQPIPSMDLHELESIVEDATSDLGYHEIPEDPLVAEEYYADAFDSYCEESDEEEEEIA 490 500 510 520 530 540 500 510 520 530 540 550 pF1KE0 LERPEKEIRNEGSQPAYRTNQQDSDIEALARCLENVLGCTSLDTKTITTMAEDMSPGPPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LERPEKEIRNEGSQPAYRTNQQDSDIEALARCLENVLGCTSLDTKTITTMAEDMSPGPPI 550 560 570 580 590 600 560 570 580 590 600 610 pF1KE0 FNSVMARTKMKRMRESAMQKLGTEVFEEVYNYLKRARHQNASEAEIRECLEKVVPQASDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNSVMARTKMKRMRESAMQKLGTEVFEEVYNYLKRARHQNASEAEIRECLEKVVPQASDC 610 620 630 640 650 660 620 630 640 pF1KE0 FEVDQLLYFEEQLLITMGKEPTLQNHL ::::::::::::::::::::::::::: XP_016 FEVDQLLYFEEQLLITMGKEPTLQNHL 670 680 >>XP_016862697 (OMIM: 609779) PREDICTED: serine/threonin (687 aa) initn: 3531 init1: 3531 opt: 3532 Z-score: 1481.6 bits: 284.5 E(85289): 8.7e-76 Smith-Waterman score: 4080; 93.8% identity (93.8% similar) in 677 aa overlap (11-645:11-687) 10 20 30 40 50 60 pF1KE0 MLKFQEAAKCVSGSTAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVL :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLKFQEAAKCVSGSTAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVL 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 KEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCE-------- :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEDLSKENCK 70 80 90 100 110 120 120 130 pF1KE0 ----------------------------------GRDLDDKIQEYKQAGKIFPENQIIEW :::::::::::::::::::::::::: XP_016 PLLNEIKEDTNKWKNIPCSWVGRINIVKMAILPKGRDLDDKIQEYKQAGKIFPENQIIEW 130 140 150 160 170 180 140 150 160 170 180 190 pF1KE0 FIQLLLGVDYMHERRILHRDLKSKNVFLKNNLLKIGDFGVSRLLMGSCDLATTLTGTPHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FIQLLLGVDYMHERRILHRDLKSKNVFLKNNLLKIGDFGVSRLLMGSCDLATTLTGTPHY 190 200 210 220 230 240 200 210 220 230 240 250 pF1KE0 MSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSIVLKIVEGDTPSLPERYPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSIVLKIVEGDTPSLPERYPK 250 260 270 280 290 300 260 270 280 290 300 310 pF1KE0 ELNAIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSEMTLEDKNLDCQKEAAHII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELNAIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSEMTLEDKNLDCQKEAAHII 310 320 330 340 350 360 320 330 340 350 360 370 pF1KE0 NAMQKRIHLQTLRALSEVQKMTPRERMRLRKLQAADEKARKLKKIVEEKYEENSKRMQEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NAMQKRIHLQTLRALSEVQKMTPRERMRLRKLQAADEKARKLKKIVEEKYEENSKRMQEL 370 380 390 400 410 420 380 390 400 410 420 430 pF1KE0 RSRNFQQLSVDVLHEKTHLKGMEEKEEQPEGRLSCSPQDEDEERWQGREEESDEPTLENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSRNFQQLSVDVLHEKTHLKGMEEKEEQPEGRLSCSPQDEDEERWQGREEESDEPTLENL 430 440 450 460 470 480 440 450 460 470 480 490 pF1KE0 PESQPIPSMDLHELESIVEDATSDLGYHEIPEDPLVAEEYYADAFDSYCEESDEEEEEIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PESQPIPSMDLHELESIVEDATSDLGYHEIPEDPLVAEEYYADAFDSYCEESDEEEEEIA 490 500 510 520 530 540 500 510 520 530 540 550 pF1KE0 LERPEKEIRNEGSQPAYRTNQQDSDIEALARCLENVLGCTSLDTKTITTMAEDMSPGPPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LERPEKEIRNEGSQPAYRTNQQDSDIEALARCLENVLGCTSLDTKTITTMAEDMSPGPPI 550 560 570 580 590 600 560 570 580 590 600 610 pF1KE0 FNSVMARTKMKRMRESAMQKLGTEVFEEVYNYLKRARHQNASEAEIRECLEKVVPQASDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNSVMARTKMKRMRESAMQKLGTEVFEEVYNYLKRARHQNASEAEIRECLEKVVPQASDC 610 620 630 640 650 660 620 630 640 pF1KE0 FEVDQLLYFEEQLLITMGKEPTLQNHL ::::::::::::::::::::::::::: XP_016 FEVDQLLYFEEQLLITMGKEPTLQNHL 670 680 645 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 18:05:18 2016 done: Sat Nov 5 18:05:19 2016 Total Scan time: 10.100 Total Display time: 0.170 Function used was FASTA [36.3.4 Apr, 2011]