FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1002, 149 aa 1>>>pF1KE1002 149 - 149 aa - 149 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5815+/-0.00106; mu= 11.2883+/- 0.064 mean_var=113.1007+/-22.111, 0's: 0 Z-trim(107.2): 133 B-trim: 5 in 1/50 Lambda= 0.120598 statistics sampled from 9265 (9430) to 9265 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.659), E-opt: 0.2 (0.29), width: 16 Scan time: 1.660 The best scores are: opt bits E(32554) CCDS9892.1 CALM1 gene_id:801|Hs108|chr14 ( 149) 959 177.1 3.5e-45 CCDS1832.1 CALM2 gene_id:805|Hs108|chr2 ( 149) 959 177.1 3.5e-45 CCDS33061.1 CALM3 gene_id:808|Hs108|chr19 ( 149) 959 177.1 3.5e-45 CCDS7069.1 CALML3 gene_id:810|Hs108|chr10 ( 149) 855 159.0 9.9e-40 CCDS13375.1 TNNC2 gene_id:7125|Hs108|chr20 ( 160) 532 102.8 8.6e-23 CCDS2857.1 TNNC1 gene_id:7134|Hs108|chr3 ( 161) 512 99.4 9.6e-22 CCDS11820.1 CETN1 gene_id:1068|Hs108|chr18 ( 172) 502 97.6 3.4e-21 CCDS14716.1 CETN2 gene_id:1069|Hs108|chrX ( 172) 496 96.6 6.9e-21 CCDS7068.1 CALML5 gene_id:51806|Hs108|chr10 ( 146) 494 96.2 7.9e-21 CCDS30566.1 CALML6 gene_id:163688|Hs108|chr1 ( 181) 440 86.9 6.2e-18 CCDS81255.1 CALML6 gene_id:163688|Hs108|chr1 ( 164) 436 86.1 9.3e-18 CCDS31834.1 MYL6 gene_id:4637|Hs108|chr12 ( 151) 435 85.9 1e-17 CCDS10226.2 CALML4 gene_id:91860|Hs108|chr15 ( 196) 434 85.9 1.3e-17 CCDS8906.1 MYL6 gene_id:4637|Hs108|chr12 ( 151) 428 84.7 2.3e-17 CCDS12709.1 CABP5 gene_id:56344|Hs108|chr19 ( 173) 422 83.7 5.2e-17 CCDS9204.1 CABP1 gene_id:9478|Hs108|chr12 ( 167) 418 83.0 8.3e-17 CCDS9205.1 CABP1 gene_id:9478|Hs108|chr12 ( 227) 418 83.2 1e-16 CCDS31913.1 CABP1 gene_id:9478|Hs108|chr12 ( 370) 418 83.4 1.4e-16 CCDS13276.1 MYL9 gene_id:10398|Hs108|chr20 ( 172) 411 81.8 2e-16 CCDS11831.1 MYL12B gene_id:103910|Hs108|chr18 ( 172) 407 81.1 3.2e-16 CCDS8905.1 MYL6B gene_id:140465|Hs108|chr12 ( 208) 406 81.0 4.1e-16 CCDS2391.1 MYL1 gene_id:4632|Hs108|chr2 ( 150) 402 80.2 5.3e-16 CCDS8170.1 CABP2 gene_id:51475|Hs108|chr11 ( 220) 403 80.5 6.1e-16 CCDS11830.1 MYL12A gene_id:10627|Hs108|chr18 ( 171) 401 80.1 6.5e-16 CCDS77145.1 MYL12A gene_id:10627|Hs108|chr18 ( 177) 401 80.1 6.7e-16 CCDS73333.1 CABP4 gene_id:57010|Hs108|chr11 ( 170) 398 79.5 9.4e-16 CCDS8166.1 CABP4 gene_id:57010|Hs108|chr11 ( 275) 398 79.8 1.3e-15 CCDS2390.1 MYL1 gene_id:4632|Hs108|chr2 ( 194) 395 79.1 1.5e-15 CCDS4066.1 CETN3 gene_id:1070|Hs108|chr5 ( 167) 385 77.3 4.4e-15 CCDS2746.1 MYL3 gene_id:4634|Hs108|chr3 ( 195) 382 76.8 7.1e-15 CCDS11510.1 MYL4 gene_id:4635|Hs108|chr17 ( 197) 360 73.0 1e-13 CCDS75274.1 CETN3 gene_id:1070|Hs108|chr5 ( 191) 342 69.9 8.7e-13 CCDS66808.1 CALML4 gene_id:91860|Hs108|chr15 ( 120) 338 68.9 1e-12 CCDS31082.1 EFCAB2 gene_id:84288|Hs108|chr1 ( 162) 322 66.3 8.7e-12 CCDS31901.1 MYL2 gene_id:4633|Hs108|chr12 ( 166) 318 65.6 1.4e-11 CCDS43197.1 MYL5 gene_id:4636|Hs108|chr4 ( 173) 314 64.9 2.4e-11 CCDS42052.1 CALML4 gene_id:91860|Hs108|chr15 ( 149) 306 63.5 5.6e-11 CCDS46310.1 PPP3R1 gene_id:5534|Hs108|chr2 ( 170) 302 62.8 1e-10 >>CCDS9892.1 CALM1 gene_id:801|Hs108|chr14 (149 aa) initn: 959 init1: 959 opt: 959 Z-score: 924.5 bits: 177.1 E(32554): 3.5e-45 Smith-Waterman score: 959; 100.0% identity (100.0% similar) in 149 aa overlap (1-149:1-149) 10 20 30 40 50 60 pF1KE1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS98 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS98 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE 70 80 90 100 110 120 130 140 pF1KE1 EVDEMIREADIDGDGQVNYEEFVQMMTAK ::::::::::::::::::::::::::::: CCDS98 EVDEMIREADIDGDGQVNYEEFVQMMTAK 130 140 >>CCDS1832.1 CALM2 gene_id:805|Hs108|chr2 (149 aa) initn: 959 init1: 959 opt: 959 Z-score: 924.5 bits: 177.1 E(32554): 3.5e-45 Smith-Waterman score: 959; 100.0% identity (100.0% similar) in 149 aa overlap (1-149:1-149) 10 20 30 40 50 60 pF1KE1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS18 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE 70 80 90 100 110 120 130 140 pF1KE1 EVDEMIREADIDGDGQVNYEEFVQMMTAK ::::::::::::::::::::::::::::: CCDS18 EVDEMIREADIDGDGQVNYEEFVQMMTAK 130 140 >>CCDS33061.1 CALM3 gene_id:808|Hs108|chr19 (149 aa) initn: 959 init1: 959 opt: 959 Z-score: 924.5 bits: 177.1 E(32554): 3.5e-45 Smith-Waterman score: 959; 100.0% identity (100.0% similar) in 149 aa overlap (1-149:1-149) 10 20 30 40 50 60 pF1KE1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE 70 80 90 100 110 120 130 140 pF1KE1 EVDEMIREADIDGDGQVNYEEFVQMMTAK ::::::::::::::::::::::::::::: CCDS33 EVDEMIREADIDGDGQVNYEEFVQMMTAK 130 140 >>CCDS7069.1 CALML3 gene_id:810|Hs108|chr10 (149 aa) initn: 1059 init1: 855 opt: 855 Z-score: 826.7 bits: 159.0 E(32554): 9.9e-40 Smith-Waterman score: 855; 84.6% identity (96.0% similar) in 149 aa overlap (1-149:1-149) 10 20 30 40 50 60 pF1KE1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG :::::::::..::::::::::::::: :::.::::::::::::::::::.::..:.: :: CCDS70 MADQLTEEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE :::.:::::: ::::::::::.:::::::::::::::::..:::::::::: :::::.:: CCDS70 NGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDE 70 80 90 100 110 120 130 140 pF1KE1 EVDEMIREADIDGDGQVNYEEFVQMMTAK ::::::: :: ::::::::::::.....: CCDS70 EVDEMIRAADTDGDGQVNYEEFVRVLVSK 130 140 >>CCDS13375.1 TNNC2 gene_id:7125|Hs108|chr20 (160 aa) initn: 529 init1: 324 opt: 532 Z-score: 522.7 bits: 102.8 E(32554): 8.6e-23 Smith-Waterman score: 532; 53.1% identity (83.4% similar) in 145 aa overlap (5-146:12-156) 10 20 30 40 50 pF1KE1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMI :.::.::::: ::..:: :: : :..:::::::: :::.::. ::. .: CCDS13 MTDQQAEARSYLSEEMIAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAII 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE1 NEVDADGNGTIDFPEFLTMMARKMKDT---DSEEEIREAFRVFDKDGNGYISAAELRHVM .::: ::.::::: :::.::.:.::. ::::. : ::.::....:::. :: ... CCDS13 EEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELAECFRIFDRNADGYIDPEELAEIF 70 80 90 100 110 120 120 130 140 pF1KE1 TNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK ::..::::.. .....: ..::.....::..:: CCDS13 RASGEHVTDEEIESLMKDGDKNNDGRIDFDEFLKMMEGVQ 130 140 150 160 >>CCDS2857.1 TNNC1 gene_id:7134|Hs108|chr3 (161 aa) initn: 521 init1: 267 opt: 512 Z-score: 503.8 bits: 99.4 E(32554): 9.6e-22 Smith-Waterman score: 512; 52.0% identity (80.4% similar) in 148 aa overlap (3-146:10-157) 10 20 30 40 50 pF1KE1 MADQLTEEQIAEFKEAFSLFDKDG-DGTITTKELGTVMRSLGQNPTEAELQDM .:::::: ::: ::..: . :: :.::::: ::: :::::: :::.: CCDS28 MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEM 10 20 30 40 50 60 60 70 80 90 100 pF1KE1 INEVDADGNGTIDFPEFLTMMARKMKDTD---SEEEIREAFRVFDKDGNGYISAAELRHV :.::: ::.::.:: :::.::.: ::: . ::::. . ::.:::...:::. ::. . CCDS28 IDEVDEDGSGTVDFDEFLVMMVRCMKDDSKGKSEEELSDLFRMFDKNADGYIDLDELKIM 70 80 90 100 110 120 110 120 130 140 pF1KE1 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK . :: .:.....:.....: ..::...:.::...: CCDS28 LQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKGVE 130 140 150 160 >>CCDS11820.1 CETN1 gene_id:1068|Hs108|chr18 (172 aa) initn: 601 init1: 500 opt: 502 Z-score: 494.1 bits: 97.6 E(32554): 3.4e-21 Smith-Waterman score: 502; 54.5% identity (83.2% similar) in 143 aa overlap (4-146:24-166) 10 20 30 40 pF1KE1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL .:::.: : .:::.::: ::.::: .::: ..::.: CCDS11 MASGFKKPSAASTGQKRKVAPKPELTEDQKQEVREAFDLFDVDGSGTIDAKELKVAMRAL 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE1 GQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGY : .: . :.. ::.::: .:.: :.: .::..:..::.. :..::: .:::.:: : .: CCDS11 GFEPRKEEMKKMISEVDREGTGKISFNDFLAVMTQKMSEKDTKEEILKAFRLFDDDETGK 70 80 90 100 110 120 110 120 130 140 pF1KE1 ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK :: .:..: ..:::.:::::..::: ::: ::::.:: :::...: CCDS11 ISFKNLKRVANELGENLTDEELQEMIDEADRDGDGEVNEEEFLRIMKKTSLY 130 140 150 160 170 >>CCDS14716.1 CETN2 gene_id:1069|Hs108|chrX (172 aa) initn: 599 init1: 494 opt: 496 Z-score: 488.4 bits: 96.6 E(32554): 6.9e-21 Smith-Waterman score: 496; 52.4% identity (82.5% similar) in 143 aa overlap (4-146:24-166) 10 20 30 40 pF1KE1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL .::::: :..:::.::: :: ::: .::: ..::.: CCDS14 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE1 GQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGY : .: . :.. ::.:.: .:.: ..: .:::.:..::.. :..::: .::..:: : .: CCDS14 GFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGK 70 80 90 100 110 120 110 120 130 140 pF1KE1 ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK :: .:..: .:::.:::::..::: ::: ::::.:. .::...: CCDS14 ISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY 130 140 150 160 170 >>CCDS7068.1 CALML5 gene_id:51806|Hs108|chr10 (146 aa) initn: 524 init1: 253 opt: 494 Z-score: 487.4 bits: 96.2 E(32554): 7.9e-21 Smith-Waterman score: 494; 51.4% identity (83.6% similar) in 146 aa overlap (1-146:1-143) 10 20 30 40 50 60 pF1KE1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG :: .:: :. :..:.::: : ::.:::...:::..... :.: .::.:. .:.:::.:: CCDS70 MAGELTPEEEAQYKKAFSAVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISEVDSDG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE .: :.: :::: :.: . . :... :::.::.::.:.:.. :::..:..::. : .: CCDS70 DGEISFQEFLTA-AKKARA--GLEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQE 70 80 90 100 110 130 140 pF1KE1 EVDEMIREADIDGDGQVNYEEFVQMMTAK :.: ::::::.: ::.::::::..:. CCDS70 ELDAMIREADVDQDGRVNYEEFARMLAQE 120 130 140 >>CCDS30566.1 CALML6 gene_id:163688|Hs108|chr1 (181 aa) initn: 415 init1: 228 opt: 440 Z-score: 435.5 bits: 86.9 E(32554): 6.2e-18 Smith-Waterman score: 440; 45.3% identity (75.3% similar) in 150 aa overlap (1-149:26-175) 10 20 30 pF1KE1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGT :...:. ::: :.: .: .::..:.: . : :: CCDS30 MGLQQEISLQPWCHHPAESCQTTTDMTERLSAEQIKEYKGVFEMFDEEGNGEVKTGELEW 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE1 VMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMA-RKMKDTDSEEEIREAFRVFD .: :: :::..:: .: ..:: :..: .. ::..:. . : ..: :.: :::::: CCDS30 LMSLLGINPTKSELASMAKDVDRDNKGFFNCDGFLALMGVYHEKAQNQESELRAAFRVFD 70 80 90 100 110 120 100 110 120 130 140 pF1KE1 KDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK :.:.:::. :..:. : :: :.. :...:..::: ::: ..::::: :::.. CCDS30 KEGKGYIDWNTLKYVLMNAGEPLNEVEAEQMMKEADKDGDRTIDYEEFVAMMTGESFKLI 130 140 150 160 170 180 CCDS30 Q 149 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:20:07 2016 done: Sat Nov 5 13:20:08 2016 Total Scan time: 1.660 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]