FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1003, 153 aa 1>>>pF1KE1003 153 - 153 aa - 153 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9771+/-0.000848; mu= 12.8920+/- 0.051 mean_var=59.5055+/-12.279, 0's: 0 Z-trim(106.0): 25 B-trim: 2 in 1/47 Lambda= 0.166263 statistics sampled from 8711 (8728) to 8711 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.268), width: 16 Scan time: 1.730 The best scores are: opt bits E(32554) CCDS2006.1 MAL gene_id:4118|Hs108|chr2 ( 153) 1001 248.3 1.4e-66 CCDS2007.1 MAL gene_id:4118|Hs108|chr2 ( 111) 591 149.8 4.4e-37 CCDS2008.1 MAL gene_id:4118|Hs108|chr2 ( 97) 421 109.0 7.3e-25 CCDS2085.1 MALL gene_id:7851|Hs108|chr2 ( 153) 396 103.1 6.8e-23 CCDS75780.1 MAL2 gene_id:114569|Hs108|chr8 ( 176) 293 78.5 2.1e-15 CCDS2652.1 CMTM8 gene_id:152189|Hs108|chr3 ( 173) 250 68.1 2.6e-12 >>CCDS2006.1 MAL gene_id:4118|Hs108|chr2 (153 aa) initn: 1001 init1: 1001 opt: 1001 Z-score: 1308.7 bits: 248.3 E(32554): 1.4e-66 Smith-Waterman score: 1001; 100.0% identity (100.0% similar) in 153 aa overlap (1-153:1-153) 10 20 30 40 50 60 pF1KE1 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVASSLVPWPLVQGWVMFVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVASSLVPWPLVQGWVMFVSV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 FCFVATTTLIILYIIGAHGGETSWVTLDAAYHCTAALFYLSASVLEALATITMQDGFTYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 FCFVATTTLIILYIIGAHGGETSWVTLDAAYHCTAALFYLSASVLEALATITMQDGFTYR 70 80 90 100 110 120 130 140 150 pF1KE1 HYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS ::::::::::::::::::::::::::::::::: CCDS20 HYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS 130 140 150 >>CCDS2007.1 MAL gene_id:4118|Hs108|chr2 (111 aa) initn: 581 init1: 581 opt: 591 Z-score: 779.3 bits: 149.8 E(32554): 4.4e-37 Smith-Waterman score: 637; 72.5% identity (72.5% similar) in 153 aa overlap (1-153:1-111) 10 20 30 40 50 60 pF1KE1 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVASSLVPWPLVQGWVMFVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVASSLVPWPLVQGWVMFVSV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 FCFVATTTLIILYIIGAHGGETSWVTLDAAYHCTAALFYLSASVLEALATITMQDGFTYR ::::::::::::::::::::::::::: CCDS20 FCFVATTTLIILYIIGAHGGETSWVTL--------------------------------- 70 80 130 140 150 pF1KE1 HYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS :::::::::::::::::::::::: CCDS20 ---------VFSYIATLLYVVHAVFSLIRWKSS 90 100 110 >>CCDS2008.1 MAL gene_id:4118|Hs108|chr2 (97 aa) initn: 421 init1: 421 opt: 421 Z-score: 559.8 bits: 109.0 E(32554): 7.3e-25 Smith-Waterman score: 498; 63.4% identity (63.4% similar) in 153 aa overlap (1-153:1-97) 10 20 30 40 50 60 pF1KE1 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVASSLVPWPLVQGWVMFVSV ::::::::::::::::::::::::::::::: CCDS20 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEF----------------------------- 10 20 30 70 80 90 100 110 120 pF1KE1 FCFVATTTLIILYIIGAHGGETSWVTLDAAYHCTAALFYLSASVLEALATITMQDGFTYR ::::::::::::::::::::::::::::::::: CCDS20 ---------------------------DAAYHCTAALFYLSASVLEALATITMQDGFTYR 40 50 60 130 140 150 pF1KE1 HYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS ::::::::::::::::::::::::::::::::: CCDS20 HYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS 70 80 90 >>CCDS2085.1 MALL gene_id:7851|Hs108|chr2 (153 aa) initn: 393 init1: 393 opt: 396 Z-score: 524.4 bits: 103.1 E(32554): 6.8e-23 Smith-Waterman score: 396; 42.8% identity (73.8% similar) in 145 aa overlap (3-147:7-150) 10 20 30 40 50 pF1KE1 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVASSLVPWPLVQGWVM ::.. . : .::: ..: :.: .:. :.::: ::: .::.. . .::.::::: CCDS20 MASPDPPATSYAPSDVPSGVALFLTIPFAFFLPELIFGFLVWTMVAATHIVYPLLQGWVM 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE1 FVSVFCFVATTTLIILYIIGAHGGETSWVTLDAAYHCTAALFYLSASVLEALATITMQDG .::. :. . ... :..: . :: .::. :: :....:.::.::.. :::. . CCDS20 YVSLTSFLISLMFLLSYLFGFYKRFESWRVLDSLYHGTTGILYMSAAVLQVHATIVSEKL 70 80 90 100 110 120 120 130 140 150 pF1KE1 FTYRHYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS . : :. : :: :..::::::..:: ::. CCDS20 LDPRIYYINSAASFFAFIATLLYILHA-FSIYYH 130 140 150 >>CCDS75780.1 MAL2 gene_id:114569|Hs108|chr8 (176 aa) initn: 342 init1: 210 opt: 293 Z-score: 390.0 bits: 78.5 E(32554): 2.1e-15 Smith-Waterman score: 338; 40.1% identity (64.5% similar) in 152 aa overlap (11-151:24-175) 10 20 30 40 pF1KE1 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVASSLVP :::.: ... : . .:..:::::::::::: :: CCDS75 MSAGGASVPPPPNPAVSFPPPRVTLPAGPDILRTYSGAFVCLEILFGGLVWILVASSNVP 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE1 WPLVQGWVMFVSVFCFVATTTLIILYIIGAHGG-ETSWVTLDAAYHCTAALFYLSASVLE ::.::::::::: : . .. ... : . ...: :: ::: :. .::..: .:: CCDS75 LPLLQGWVMFVSVTAFFFSLLFLGMFLSGMVAQIDANWNFLDFAYHFTVFVFYFGAFLLE 70 80 90 100 110 120 110 120 130 140 150 pF1KE1 ALAT----------ITMQDGFTYRHYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS : :: :: : .. .:. :.:: .:....: : ..: ::. CCDS75 AAATSLHDLHCNTTITGQPLLSDNQYNINVAASIFAFMTTACYGCSLGLALRRWRP 130 140 150 160 170 >>CCDS2652.1 CMTM8 gene_id:152189|Hs108|chr3 (173 aa) initn: 184 init1: 148 opt: 250 Z-score: 334.4 bits: 68.1 E(32554): 2.6e-12 Smith-Waterman score: 250; 30.2% identity (66.4% similar) in 149 aa overlap (6-152:24-169) 10 20 30 40 pF1KE1 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVA .:..:.. . ::: .:.. :...: ::: :.: CCDS26 MEEPQRARSHTVTTTASSFAENFSTSSSSFAYDREFLRTLPGFLIVAEIVLGLLVWTLIA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE1 SSLVPWPLVQGWVMFVSVFCFVATTTLIILYIIGAHG--GETSWVTLDAAYHCTAALFYL .. . ::::::.:: .: :. ..:.:: .. .. :.:. .. .: ..:: CCDS26 GTEYFRVPAFGWVMFVAVFYWVLTVFFLIIYITMTYTRIPQVPWTTVGLCFNGSAFVLYL 70 80 90 100 110 120 110 120 130 140 150 pF1KE1 SASVLEALATITMQDGFTYRHYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS ::.:..: .. .:. .. . :. :....:. :. .. ::.: :.: CCDS26 SAAVVDASSVSPERDSHNFNSW---AASSFFAFLVTICYAGNTYFSFIAWRSRTIQ 130 140 150 160 170 153 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:20:55 2016 done: Sat Nov 5 13:20:56 2016 Total Scan time: 1.730 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]