FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1004, 162 aa 1>>>pF1KE1004 162 - 162 aa - 162 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7669+/-0.000667; mu= 14.7103+/- 0.040 mean_var=56.2261+/-11.242, 0's: 0 Z-trim(109.1): 16 B-trim: 207 in 1/51 Lambda= 0.171043 statistics sampled from 10661 (10672) to 10661 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.722), E-opt: 0.2 (0.328), width: 16 Scan time: 1.600 The best scores are: opt bits E(32554) CCDS8047.1 PLA2G16 gene_id:11145|Hs108|chr11 ( 162) 1068 271.0 2.2e-73 CCDS8046.1 HRASLS2 gene_id:54979|Hs108|chr11 ( 162) 728 187.2 3.9e-48 CCDS41662.1 RARRES3 gene_id:5920|Hs108|chr11 ( 164) 543 141.5 2.2e-34 CCDS3303.2 HRASLS gene_id:57110|Hs108|chr3 ( 273) 487 127.8 4.8e-30 CCDS53646.1 HRASLS5 gene_id:117245|Hs108|chr11 ( 269) 455 119.9 1.1e-27 CCDS8044.1 HRASLS5 gene_id:117245|Hs108|chr11 ( 279) 455 119.9 1.2e-27 CCDS53647.1 HRASLS5 gene_id:117245|Hs108|chr11 ( 253) 353 94.7 4.1e-20 >>CCDS8047.1 PLA2G16 gene_id:11145|Hs108|chr11 (162 aa) initn: 1068 init1: 1068 opt: 1068 Z-score: 1431.0 bits: 271.0 E(32554): 2.2e-73 Smith-Waterman score: 1068; 100.0% identity (100.0% similar) in 162 aa overlap (1-162:1-162) 10 20 30 40 50 60 pF1KE1 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS80 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS80 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL 70 80 90 100 110 120 130 140 150 160 pF1KE1 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ :::::::::::::::::::::::::::::::::::::::::: CCDS80 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ 130 140 150 160 >>CCDS8046.1 HRASLS2 gene_id:54979|Hs108|chr11 (162 aa) initn: 729 init1: 709 opt: 728 Z-score: 977.6 bits: 187.2 E(32554): 3.9e-48 Smith-Waterman score: 728; 69.4% identity (89.8% similar) in 157 aa overlap (6-162:6-162) 10 20 30 40 50 60 pF1KE1 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV :.:. :::::: : : :::::::::::::::: ::.::::::::.::::.:::: CCDS80 MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL ::::: :::.:.:.:::::::.:.::: .::..:::::::::. :.:::.:::::::.: CCDS80 KKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHL 70 80 90 100 110 120 130 140 150 160 pF1KE1 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ ::::.::::: .. ...::. ::: ::.:....:.::..: CCDS80 RYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ 130 140 150 160 >>CCDS41662.1 RARRES3 gene_id:5920|Hs108|chr11 (164 aa) initn: 514 init1: 514 opt: 543 Z-score: 730.8 bits: 141.5 E(32554): 2.2e-34 Smith-Waterman score: 543; 51.2% identity (77.8% similar) in 162 aa overlap (1-162:1-161) 10 20 30 40 50 60 pF1KE1 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV : .: :::::::::::: :.:::.:.:::::.::::::: :::..::.:.:...: : CCDS41 MASPHQEPKPGDLIEIFRLGYEHWALYIGDGYVIHLAPPSEYPGAGSSSVFSVLSNSAEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL :.: : ::.:. :.:::. : .:.: : ::. :.:.:::.. :...:.::::::..: CCDS41 KRERLEDVVGGCCYRVNNSLDHEYQPRPVEVIISSAKEMVGQKMKYSIVSRNCEHFVTQL 70 80 90 100 110 120 130 140 150 160 pF1KE1 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ ::: .: ::. . . ..:: .:. . . : :. . ::. CCDS41 RYGKSRCKQVEKAKVEVGVA-TALGILVVAGCSFAIRRYQKKATA 130 140 150 160 >>CCDS3303.2 HRASLS gene_id:57110|Hs108|chr3 (273 aa) initn: 454 init1: 285 opt: 487 Z-score: 652.9 bits: 127.8 E(32554): 4.8e-30 Smith-Waterman score: 487; 46.8% identity (79.2% similar) in 154 aa overlap (8-161:120-271) 10 20 30 pF1KE1 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLA : ::::::.::: :.:::.:.:::::...: CCDS33 TQLPPGARRRPRLESEMAFNDCFSLNYPGNPCPGDLIEVFRPGYQHWALYLGDGYVINIA 90 100 110 120 130 140 40 50 60 70 80 90 pF1KE1 PPSEVAGAGAASVMSALTDKAIVKKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAE : . . :. .:. :....::.:: .:: ::.:.: :..:::.:. : ::: .::.:.: CCDS33 PVDGIP-ASFTSAKSVFSSKALVKMQLLKDVVGNDTYRINNKYDETYPPLPVEEIIKRSE 150 160 170 180 190 200 100 110 120 130 140 150 pF1KE1 ELVGQEVLYKLTSENCEHFVNELRYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRN ..:::: :.: .::::::. :::: . :.:. .: .. . .....:..: .: .. CCDS33 FVIGQEVAYNLLVNNCEHFVTLLRYGEGVSEQANRAISTVEFVTAAVGVFSFLG-LFPKG 210 220 230 240 250 260 160 pF1KE1 KRQKQ .: : CCDS33 QRAKYY 270 >>CCDS53646.1 HRASLS5 gene_id:117245|Hs108|chr11 (269 aa) initn: 419 init1: 237 opt: 455 Z-score: 610.3 bits: 119.9 E(32554): 1.1e-27 Smith-Waterman score: 455; 52.4% identity (75.5% similar) in 143 aa overlap (6-147:118-258) 10 20 30 pF1KE1 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVH :.:.::::::::: :.:::::: : ::: CCDS53 ETTPSQKADWSSIPKPENEGKLIKQAAEGKPRPRPGDLIEIFRIGYEHWAIYVEDDCVVH 90 100 110 120 130 140 40 50 60 70 80 90 pF1KE1 LAPPSEVAGAGAASVMSALTDKAIVKKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQR :::::: .: :. : ....:.:: : :: . ...:::: : : ::: .::::: CCDS53 LAPPSEEFEVG--SITSIFSNRAVVKYSRLEDVLHGCSWKVNNKLDGTYLPLPVDKIIQR 150 160 170 180 190 200 100 110 120 130 140 150 pF1KE1 AEELVGQEVLYKLTSENCEHFVNELRYGVARSDQVRDVII-AASVAGMGLAAMSLIGVMF ....:.. : :.: ::::::: ::::: ::.::. ... .:..:: ..:. CCDS53 TKKMVNKIVQYSLIEGNCEHFVNGLRYGVPRSQQVEHALMEGAKAAGAVISAVVDSIKPK 210 220 230 240 250 260 160 pF1KE1 SRNKRQKQ CCDS53 PITA >>CCDS8044.1 HRASLS5 gene_id:117245|Hs108|chr11 (279 aa) initn: 419 init1: 237 opt: 455 Z-score: 610.1 bits: 119.9 E(32554): 1.2e-27 Smith-Waterman score: 455; 52.4% identity (75.5% similar) in 143 aa overlap (6-147:128-268) 10 20 30 pF1KE1 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVH :.:.::::::::: :.:::::: : ::: CCDS80 ETTPSQKADWSSIPKPENEGKLIKQAAEGKPRPRPGDLIEIFRIGYEHWAIYVEDDCVVH 100 110 120 130 140 150 40 50 60 70 80 90 pF1KE1 LAPPSEVAGAGAASVMSALTDKAIVKKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQR :::::: .: :. : ....:.:: : :: . ...:::: : : ::: .::::: CCDS80 LAPPSEEFEVG--SITSIFSNRAVVKYSRLEDVLHGCSWKVNNKLDGTYLPLPVDKIIQR 160 170 180 190 200 210 100 110 120 130 140 150 pF1KE1 AEELVGQEVLYKLTSENCEHFVNELRYGVARSDQVRDVII-AASVAGMGLAAMSLIGVMF ....:.. : :.: ::::::: ::::: ::.::. ... .:..:: ..:. CCDS80 TKKMVNKIVQYSLIEGNCEHFVNGLRYGVPRSQQVEHALMEGAKAAGAVISAVVDSIKPK 220 230 240 250 260 270 160 pF1KE1 SRNKRQKQ CCDS80 PITA >>CCDS53647.1 HRASLS5 gene_id:117245|Hs108|chr11 (253 aa) initn: 354 init1: 196 opt: 353 Z-score: 474.7 bits: 94.7 E(32554): 4.1e-20 Smith-Waterman score: 353; 52.8% identity (73.1% similar) in 108 aa overlap (6-113:128-233) 10 20 30 pF1KE1 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVH :.:.::::::::: :.:::::: : ::: CCDS53 ETTPSQKADWSSIPKPENEGKLIKQAAEGKPRPRPGDLIEIFRIGYEHWAIYVEDDCVVH 100 110 120 130 140 150 40 50 60 70 80 90 pF1KE1 LAPPSEVAGAGAASVMSALTDKAIVKKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQR :::::: .: :. : ....:.:: : :: . ...:::: : : ::: .::::: CCDS53 LAPPSEEFEVG--SITSIFSNRAVVKYSRLEDVLHGCSWKVNNKLDGTYLPLPVDKIIQR 160 170 180 190 200 210 100 110 120 130 140 150 pF1KE1 AEELVGQEVLYKLTSENCEHFVNELRYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFS ....:.. : :.: :: CCDS53 TKKMVNKIVQYSLIEGNCRARPDGRSEGCWSSYFSCSG 220 230 240 250 162 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:21:23 2016 done: Sat Nov 5 13:21:23 2016 Total Scan time: 1.600 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]