FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1006, 187 aa 1>>>pF1KE1006 187 - 187 aa - 187 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0281+/-0.000294; mu= 14.4555+/- 0.018 mean_var=63.8296+/-12.952, 0's: 0 Z-trim(117.4): 22 B-trim: 0 in 0/52 Lambda= 0.160533 statistics sampled from 29269 (29291) to 29269 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.742), E-opt: 0.2 (0.343), width: 16 Scan time: 5.990 The best scores are: opt bits E(85289) NP_002558 (OMIM: 604591) phosphatidylethanolamine- ( 187) 1303 309.8 1.6e-84 NP_115867 (OMIM: 611844) 39S ribosomal protein L38 ( 380) 276 72.1 1.2e-12 XP_011542716 (OMIM: 612473) PREDICTED: phosphatidy ( 227) 273 71.3 1.2e-12 NP_659399 (OMIM: 612473) phosphatidylethanolamine- ( 227) 273 71.3 1.2e-12 >>NP_002558 (OMIM: 604591) phosphatidylethanolamine-bind (187 aa) initn: 1303 init1: 1303 opt: 1303 Z-score: 1638.2 bits: 309.8 E(85289): 1.6e-84 Smith-Waterman score: 1303; 100.0% identity (100.0% similar) in 187 aa overlap (1-187:1-187) 10 20 30 40 50 60 pF1KE1 MPVDLSKWSGPLSLQEVDEQPQHPLHVTYAGAAVDELGKVLTPTQVKNRPTSISWDGLDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MPVDLSKWSGPLSLQEVDEQPQHPLHVTYAGAAVDELGKVLTPTQVKNRPTSISWDGLDS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 GKLYTLVLTDPDAPSRKDPKYREWHHFLVVNMKGNDISSGTVLSDYVGSGPPKGTGLHRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GKLYTLVLTDPDAPSRKDPKYREWHHFLVVNMKGNDISSGTVLSDYVGSGPPKGTGLHRY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 VWLVYEQDRPLKCDEPILSNRSGDHRGKFKVASFRKKYELRAPVAGTCYQAEWDDYVPKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VWLVYEQDRPLKCDEPILSNRSGDHRGKFKVASFRKKYELRAPVAGTCYQAEWDDYVPKL 130 140 150 160 170 180 pF1KE1 YEQLSGK ::::::: NP_002 YEQLSGK >>NP_115867 (OMIM: 611844) 39S ribosomal protein L38, mi (380 aa) initn: 215 init1: 149 opt: 276 Z-score: 348.3 bits: 72.1 E(85289): 1.2e-12 Smith-Waterman score: 276; 31.2% identity (64.1% similar) in 170 aa overlap (21-184:169-334) 10 20 30 40 pF1KE1 MPVDLSKWSGPLSLQEVDEQPQHPLHVTYAGAAVDEL----GKVLTPTQV :. ::::.:: . : . :. .:::.. NP_115 WERTCGPYHKQRLAEYYGLYRDLFHGATFVPRVPLHVAYAVGEDDLMPVYCGNEVTPTEA 140 150 160 170 180 190 50 60 70 80 90 100 pF1KE1 KNRPTSISWDGLDSGKLYTLVLTDPDAPSRKDPKYREWHHFLVVNMKGNDISSGTVLSDY . : ..... . :.:.::.::. :. .: :. :.:..:. :: .. : : : NP_115 AQAPE-VTYEA-EEGSLWTLLLTSLDG-HLLEPDA-EYLHWLLTNIPGNRVAEGQVTCPY 200 210 220 230 240 250 110 120 130 140 150 160 pF1KE1 VGSGPPKGTGLHRYVWLVYEQDRPLKCDEPILSNRSGDHRGK-FKVASFRKKY-ELRAPV . : .:.:.:: ..:...::.:. .: . . . :.. .: ::. : .:. NP_115 LPPFPARGSGIHRLAFLLFKQDQPIDFSEDARPSPCYQLAQRTFRTFDFYKKHQETMTPA 260 270 280 290 300 310 170 180 pF1KE1 AGTCYQAEWDDYVPKLYEQLSGK . . .: .::: : ...:: NP_115 GLSFFQCRWDDSVTYIFHQLLDMREPVFEFVRPPPYHPKQKRFPHRQPLRYLDRYRDSHE 320 330 340 350 360 370 >>XP_011542716 (OMIM: 612473) PREDICTED: phosphatidyleth (227 aa) initn: 239 init1: 170 opt: 273 Z-score: 347.8 bits: 71.3 E(85289): 1.2e-12 Smith-Waterman score: 274; 32.7% identity (59.1% similar) in 159 aa overlap (36-180:52-206) 10 20 30 40 50 pF1KE1 SKWSGPLSLQEVDEQPQHPLHVTYAGAAVDELGKV---LTPTQVKNRPTSISW------- :::.. ..: . : :: XP_011 GDEDENSPCAHEALLDEDTLFCQGLEVFYPELGNIGCKVVPDCNNYRQKITSWMEPIVKF 30 40 50 60 70 80 60 70 80 90 100 110 pF1KE1 DGLDSGKLYTLVLTDPDAPSRKDPKYREWHHFLVVNMKGNDISSGTV----LSDYVGSGP : .: : ::..::::::: .:. : :.:.::...:: :...: . :: : . .: XP_011 PGAVDGATYILVMVDPDAPSRAEPRQRFWRHWLVTDIKGADLKKGKIQGQELSAYQAPSP 90 100 110 120 130 140 120 130 140 150 160 170 pF1KE1 PKGTGLHRYVWLVYEQDRPLKCDEPILSNRSGDHRGKFKVASFRKKYELRAPVAGTCYQA : .:.::: ..:: :. . : . . ::..:. : ....: : :.: ... XP_011 PAHSGFHRYQFFVYLQEGKVISLLP----KENKTRGSWKMDRFLNRFHLGEPEASTQFMT 150 160 170 180 190 180 pF1KE1 EWDDYVPKLYEQLSGK . . : : XP_011 QNYQDSPTLQAPRERASEPKHKNQAEIAAC 200 210 220 >>NP_659399 (OMIM: 612473) phosphatidylethanolamine-bind (227 aa) initn: 239 init1: 170 opt: 273 Z-score: 347.8 bits: 71.3 E(85289): 1.2e-12 Smith-Waterman score: 274; 32.7% identity (59.1% similar) in 159 aa overlap (36-180:52-206) 10 20 30 40 50 pF1KE1 SKWSGPLSLQEVDEQPQHPLHVTYAGAAVDELGKV---LTPTQVKNRPTSISW------- :::.. ..: . : :: NP_659 GDEDENSPCAHEALLDEDTLFCQGLEVFYPELGNIGCKVVPDCNNYRQKITSWMEPIVKF 30 40 50 60 70 80 60 70 80 90 100 110 pF1KE1 DGLDSGKLYTLVLTDPDAPSRKDPKYREWHHFLVVNMKGNDISSGTV----LSDYVGSGP : .: : ::..::::::: .:. : :.:.::...:: :...: . :: : . .: NP_659 PGAVDGATYILVMVDPDAPSRAEPRQRFWRHWLVTDIKGADLKKGKIQGQELSAYQAPSP 90 100 110 120 130 140 120 130 140 150 160 170 pF1KE1 PKGTGLHRYVWLVYEQDRPLKCDEPILSNRSGDHRGKFKVASFRKKYELRAPVAGTCYQA : .:.::: ..:: :. . : . . ::..:. : ....: : :.: ... NP_659 PAHSGFHRYQFFVYLQEGKVISLLP----KENKTRGSWKMDRFLNRFHLGEPEASTQFMT 150 160 170 180 190 180 pF1KE1 EWDDYVPKLYEQLSGK . . : : NP_659 QNYQDSPTLQAPRERASEPKHKNQAEIAAC 200 210 220 187 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:22:24 2016 done: Sat Nov 5 13:22:25 2016 Total Scan time: 5.990 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]