FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1012, 302 aa 1>>>pF1KE1012 302 - 302 aa - 302 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7696+/-0.000778; mu= 12.9050+/- 0.047 mean_var=64.3914+/-13.242, 0's: 0 Z-trim(107.7): 21 B-trim: 250 in 1/49 Lambda= 0.159831 statistics sampled from 9744 (9762) to 9744 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.671), E-opt: 0.2 (0.3), width: 16 Scan time: 2.630 The best scores are: opt bits E(32554) CCDS10464.1 ECI1 gene_id:1632|Hs108|chr16 ( 302) 1966 461.8 2.8e-130 CCDS58410.1 ECI1 gene_id:1632|Hs108|chr16 ( 285) 1136 270.4 1.1e-72 CCDS6689.1 AUH gene_id:549|Hs108|chr9 ( 339) 258 68.0 1.1e-11 CCDS1721.1 HADHA gene_id:3030|Hs108|chr2 ( 763) 259 68.3 2.1e-11 >>CCDS10464.1 ECI1 gene_id:1632|Hs108|chr16 (302 aa) initn: 1966 init1: 1966 opt: 1966 Z-score: 2452.3 bits: 461.8 E(32554): 2.8e-130 Smith-Waterman score: 1966; 100.0% identity (100.0% similar) in 302 aa overlap (1-302:1-302) 10 20 30 40 50 60 pF1KE1 MALVASVRVPARVLLRAGARLPGAALGRTERAAGGGDGARRFGSQRVLVEPDAGAGVAVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MALVASVRVPARVLLRAGARLPGAALGRTERAAGGGDGARRFGSQRVLVEPDAGAGVAVM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 KFKNPPVNSLSLEFLTELVISLEKLENDKSFRGVILTSDRPGVFSAGLDLTEMCGRSPAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 KFKNPPVNSLSLEFLTELVISLEKLENDKSFRGVILTSDRPGVFSAGLDLTEMCGRSPAH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 YAGYWKAVQELWLRLYQSNLVLVSAINGACPAGGCLVALTCDYRILADNPRYCIGLNETQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 YAGYWKAVQELWLRLYQSNLVLVSAINGACPAGGCLVALTCDYRILADNPRYCIGLNETQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 LGIIAPFWLKDTLENTIGHRAAERALQLGLLFPPAEALQVGIVDQVVPEEQVQSTALSAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 LGIIAPFWLKDTLENTIGHRAAERALQLGLLFPPAEALQVGIVDQVVPEEQVQSTALSAI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 AQWMAIPDHARQLTKAMMRKATASRLVTQRDADVQNFVSFISKDSIQKSLQMYLERLKEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 AQWMAIPDHARQLTKAMMRKATASRLVTQRDADVQNFVSFISKDSIQKSLQMYLERLKEE 250 260 270 280 290 300 pF1KE1 KG :: CCDS10 KG >>CCDS58410.1 ECI1 gene_id:1632|Hs108|chr16 (285 aa) initn: 1827 init1: 1126 opt: 1136 Z-score: 1418.3 bits: 270.4 E(32554): 1.1e-72 Smith-Waterman score: 1797; 94.4% identity (94.4% similar) in 302 aa overlap (1-302:1-285) 10 20 30 40 50 60 pF1KE1 MALVASVRVPARVLLRAGARLPGAALGRTERAAGGGDGARRFGSQRVLVEPDAGAGVAVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MALVASVRVPARVLLRAGARLPGAALGRTERAAGGGDGARRFGSQRVLVEPDAGAGVAVM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 KFKNPPVNSLSLEFLTELVISLEKLENDKSFRGVILTSDRPGVFSAGLDLTEMCGRSPAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 KFKNPPVNSLSLEFLTELVISLEKLENDKSFRGVILTSDRPGVFSAGLDLTEMCGRSPAH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 YAGYWKAVQELWLRLYQSNLVLVSAINGACPAGGCLVALTCDYRILADNPRYCIGLNETQ ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 YAGYWKAVQELWLRLYQSNLVLVSAINGACPAGGCLVALTCDYRILADNPR--------- 130 140 150 160 170 190 200 210 220 230 240 pF1KE1 LGIIAPFWLKDTLENTIGHRAAERALQLGLLFPPAEALQVGIVDQVVPEEQVQSTALSAI :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 --------LKDTLENTIGHRAAERALQLGLLFPPAEALQVGIVDQVVPEEQVQSTALSAI 180 190 200 210 220 250 260 270 280 290 300 pF1KE1 AQWMAIPDHARQLTKAMMRKATASRLVTQRDADVQNFVSFISKDSIQKSLQMYLERLKEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 AQWMAIPDHARQLTKAMMRKATASRLVTQRDADVQNFVSFISKDSIQKSLQMYLERLKEE 230 240 250 260 270 280 pF1KE1 KG :: CCDS58 KG >>CCDS6689.1 AUH gene_id:549|Hs108|chr9 (339 aa) initn: 270 init1: 179 opt: 258 Z-score: 322.9 bits: 68.0 E(32554): 1.1e-11 Smith-Waterman score: 269; 25.6% identity (52.9% similar) in 308 aa overlap (18-302:33-338) 10 20 30 pF1KE1 MALVASVRVPARVLLRAGARLPGAALGRTER----------AAGGGD : ::::. :: :::: CCDS66 AAVAAAPGALGSLHAGGARLVAACSAWLCPGLRLPGSLAGRRAGPAIWAQGWVPAAGGPA 10 20 30 40 50 60 40 50 60 70 80 pF1KE1 GARRFGSQ-------RVLVEPDAGAGVAVMKF-KNPPVNSLSLEFLTELVISLEKLENDK : ..:. :: . . :..:. . . :::: ... : ... :..:: CCDS66 PKRGYSSEMKTEDELRVRHLEEENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDK 70 80 90 100 110 120 90 100 110 120 130 140 pF1KE1 SFRGVILTSDRPGVFSAGLDLTEMCGRSPAHYAGYWKAVQELWLRLYQSNLVLVSAINGA . : .:. :. ::.: :: :: : : .. . . . .. . . . . ..::.: CCDS66 KVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDIANLPVPTIAAIDGL 130 140 150 160 170 180 150 160 170 180 190 200 pF1KE1 CPAGGCLVALTCDYRILADNPRYCIGLNETQLGIIAPFWLKDTLENTIGHRAAERALQLG .:: .::.:: :. :.. . .:: ::.:.:: . : .:: :.. . . CCDS66 ALGGGLELALACDIRVAASSAK--MGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSA 190 200 210 220 230 240 210 220 230 240 250 260 pF1KE1 LLFPPAEALQVGIVDQVVPEEQ----VQSTALSAIAQWMAIPDHARQLTKAMMRKATASR .. :: ::....:. ..: . ::. ... : ...: . .. CCDS66 RVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVD 250 260 270 280 290 300 270 280 290 300 pF1KE1 LVTQRDADVQNFVSFI-SKDSIQKSLQMYLERLKEEKG ::: . ... : .:: .. : . .: . :: CCDS66 LVTGLAIEEACYAQTIPTKDRLEGLLAFKEKRPPRYKGE 310 320 330 >>CCDS1721.1 HADHA gene_id:3030|Hs108|chr2 (763 aa) initn: 233 init1: 148 opt: 259 Z-score: 318.4 bits: 68.3 E(32554): 2.1e-11 Smith-Waterman score: 259; 29.1% identity (61.7% similar) in 196 aa overlap (40-227:27-222) 10 20 30 40 50 60 pF1KE1 PARVLLRAGARLPGAALGRTERAAGGGDGARRF-GSQRVLVEPDAGAGV----AVMKFKN : : ::. .:.. . :: ::..... CCDS17 MVACRAIGILSRFSAFRILRSRGYICRNFTGSSALLTRTHINYGVKGDVAVVRINS 10 20 30 40 50 70 80 90 100 110 120 pF1KE1 P--PVNSLSLEFLTELVISLEKLENDKSFRGVILTSDRPGVFSAGLDLTEMCG-RSPAHY : ::.:: :. .:. .... . ..:...: :..:: : :: :.. . . .. . CCDS17 PNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLAACKTLQEV 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE1 AGYWKAVQELWLRLYQSNLVLVSAINGACPAGGCLVALTCDYRILADNPRYCIGLNETQL . . .:.. .: .:. .:.::::.: .:: ::..:.::: . . . .: :. : CCDS17 TQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLL 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE1 GIIAPFWLKDTLENTIGHRAAERALQLGLLFPPAEALQVGIVDQVVPEEQVQSTALSAIA : . . : . .: :: . : . .: ..:.:::.: CCDS17 GALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEPLGPGLKPPEERT 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE1 QWMAIPDHARQLTKAMMRKATASRLVTQRDADVQNFVSFISKDSIQKSLQMYLERLKEEK CCDS17 IEYLEEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTIPFVRQQVYKKVEEKVRKQTKG 240 250 260 270 280 290 302 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 20:16:22 2016 done: Sun Nov 6 20:16:23 2016 Total Scan time: 2.630 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]