Result of FASTA (omim) for pF1KE1012
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1012, 302 aa
  1>>>pF1KE1012 302 - 302 aa - 302 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3799+/-0.000348; mu= 15.0277+/- 0.022
 mean_var=63.9657+/-13.251, 0's: 0 Z-trim(114.2): 30  B-trim: 1365 in 1/50
 Lambda= 0.160362
 statistics sampled from 23918 (23948) to 23918 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.653), E-opt: 0.2 (0.281), width:  16
 Scan time:  7.860

The best scores are:                                      opt bits E(85289)
NP_001910 (OMIM: 600305) enoyl-CoA delta isomerase ( 302) 1966 463.4 2.5e-130
NP_001171500 (OMIM: 600305) enoyl-CoA delta isomer ( 285) 1136 271.4 1.5e-72
NP_001689 (OMIM: 250950,600529) methylglutaconyl-C ( 339)  258 68.3 2.5e-11
NP_000173 (OMIM: 600890,609015,609016) trifunction ( 763)  259 68.7 4.2e-11
XP_016870338 (OMIM: 250950,600529) PREDICTED: meth ( 323)  248 65.9 1.2e-10
XP_005252123 (OMIM: 250950,600529) PREDICTED: meth ( 349)  246 65.5 1.7e-10
XP_005252126 (OMIM: 250950,600529) PREDICTED: meth ( 298)  236 63.2 7.5e-10
XP_005252124 (OMIM: 250950,600529) PREDICTED: meth ( 333)  236 63.2 8.2e-10
XP_011517104 (OMIM: 250950,600529) PREDICTED: meth ( 230)  227 61.0 2.5e-09
XP_016870339 (OMIM: 250950,600529) PREDICTED: meth ( 230)  227 61.0 2.5e-09
XP_016870340 (OMIM: 250950,600529) PREDICTED: meth ( 214)  217 58.7 1.2e-08
XP_005252129 (OMIM: 250950,600529) PREDICTED: meth ( 255)  217 58.7 1.4e-08
XP_005267105 (OMIM: 612136) PREDICTED: ethylmalony ( 301)  212 57.6 3.5e-08
XP_005267104 (OMIM: 612136) PREDICTED: ethylmalony ( 301)  212 57.6 3.5e-08
NP_001002030 (OMIM: 612136) ethylmalonyl-CoA decar ( 301)  212 57.6 3.5e-08
NP_001132982 (OMIM: 612136) ethylmalonyl-CoA decar ( 307)  212 57.6 3.6e-08
NP_001957 (OMIM: 607037,615605) peroxisomal bifunc ( 723)  213 58.0 6.4e-08
NP_004083 (OMIM: 602292,616277) enoyl-CoA hydratas ( 290)  206 56.2   9e-08
XP_011517102 (OMIM: 250950,600529) PREDICTED: meth ( 265)  205 56.0 9.7e-08
XP_016866545 (OMIM: 612136) PREDICTED: ethylmalony ( 226)  181 50.4   4e-06
NP_001099014 (OMIM: 612136) ethylmalonyl-CoA decar ( 226)  181 50.4   4e-06
XP_011534244 (OMIM: 612136) PREDICTED: ethylmalony ( 189)  149 42.9 0.00058
XP_016881937 (OMIM: 600696) PREDICTED: delta(3,5)- ( 248)  134 39.5  0.0081


>>NP_001910 (OMIM: 600305) enoyl-CoA delta isomerase 1,   (302 aa)
 initn: 1966 init1: 1966 opt: 1966  Z-score: 2460.9  bits: 463.4 E(85289): 2.5e-130
Smith-Waterman score: 1966; 100.0% identity (100.0% similar) in 302 aa overlap (1-302:1-302)

               10        20        30        40        50        60
pF1KE1 MALVASVRVPARVLLRAGARLPGAALGRTERAAGGGDGARRFGSQRVLVEPDAGAGVAVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MALVASVRVPARVLLRAGARLPGAALGRTERAAGGGDGARRFGSQRVLVEPDAGAGVAVM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 KFKNPPVNSLSLEFLTELVISLEKLENDKSFRGVILTSDRPGVFSAGLDLTEMCGRSPAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFKNPPVNSLSLEFLTELVISLEKLENDKSFRGVILTSDRPGVFSAGLDLTEMCGRSPAH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 YAGYWKAVQELWLRLYQSNLVLVSAINGACPAGGCLVALTCDYRILADNPRYCIGLNETQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YAGYWKAVQELWLRLYQSNLVLVSAINGACPAGGCLVALTCDYRILADNPRYCIGLNETQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 LGIIAPFWLKDTLENTIGHRAAERALQLGLLFPPAEALQVGIVDQVVPEEQVQSTALSAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGIIAPFWLKDTLENTIGHRAAERALQLGLLFPPAEALQVGIVDQVVPEEQVQSTALSAI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 AQWMAIPDHARQLTKAMMRKATASRLVTQRDADVQNFVSFISKDSIQKSLQMYLERLKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQWMAIPDHARQLTKAMMRKATASRLVTQRDADVQNFVSFISKDSIQKSLQMYLERLKEE
              250       260       270       280       290       300

         
pF1KE1 KG
       ::
NP_001 KG
         

>>NP_001171500 (OMIM: 600305) enoyl-CoA delta isomerase   (285 aa)
 initn: 1827 init1: 1126 opt: 1136  Z-score: 1423.5  bits: 271.4 E(85289): 1.5e-72
Smith-Waterman score: 1797; 94.4% identity (94.4% similar) in 302 aa overlap (1-302:1-285)

               10        20        30        40        50        60
pF1KE1 MALVASVRVPARVLLRAGARLPGAALGRTERAAGGGDGARRFGSQRVLVEPDAGAGVAVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MALVASVRVPARVLLRAGARLPGAALGRTERAAGGGDGARRFGSQRVLVEPDAGAGVAVM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 KFKNPPVNSLSLEFLTELVISLEKLENDKSFRGVILTSDRPGVFSAGLDLTEMCGRSPAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFKNPPVNSLSLEFLTELVISLEKLENDKSFRGVILTSDRPGVFSAGLDLTEMCGRSPAH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 YAGYWKAVQELWLRLYQSNLVLVSAINGACPAGGCLVALTCDYRILADNPRYCIGLNETQ
       :::::::::::::::::::::::::::::::::::::::::::::::::::         
NP_001 YAGYWKAVQELWLRLYQSNLVLVSAINGACPAGGCLVALTCDYRILADNPR---------
              130       140       150       160       170          

              190       200       210       220       230       240
pF1KE1 LGIIAPFWLKDTLENTIGHRAAERALQLGLLFPPAEALQVGIVDQVVPEEQVQSTALSAI
               ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --------LKDTLENTIGHRAAERALQLGLLFPPAEALQVGIVDQVVPEEQVQSTALSAI
                     180       190       200       210       220   

              250       260       270       280       290       300
pF1KE1 AQWMAIPDHARQLTKAMMRKATASRLVTQRDADVQNFVSFISKDSIQKSLQMYLERLKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQWMAIPDHARQLTKAMMRKATASRLVTQRDADVQNFVSFISKDSIQKSLQMYLERLKEE
           230       240       250       260       270       280   

         
pF1KE1 KG
       ::
NP_001 KG
         

>>NP_001689 (OMIM: 250950,600529) methylglutaconyl-CoA h  (339 aa)
 initn: 270 init1: 179 opt: 258  Z-score: 324.5  bits: 68.3 E(85289): 2.5e-11
Smith-Waterman score: 269; 25.6% identity (52.9% similar) in 308 aa overlap (18-302:33-338)

                            10        20        30                 
pF1KE1              MALVASVRVPARVLLRAGARLPGAALGRTER----------AAGGGD
                                     : ::::.  ::             ::::  
NP_001 AAVAAAPGALGSLHAGGARLVAACSAWLCPGLRLPGSLAGRRAGPAIWAQGWVPAAGGPA
             10        20        30        40        50        60  

        40               50        60         70        80         
pF1KE1 GARRFGSQ-------RVLVEPDAGAGVAVMKF-KNPPVNSLSLEFLTELVISLEKLENDK
         : ..:.       ::    . . :..:. . .    :::: ...  :  ... :..::
NP_001 PKRGYSSEMKTEDELRVRHLEEENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDK
             70        80        90       100       110       120  

      90       100       110       120       130       140         
pF1KE1 SFRGVILTSDRPGVFSAGLDLTEMCGRSPAHYAGYWKAVQELWLRLYQSNLVLVSAINGA
       . : .:. :. ::.: :: :: :    : .. . . . .. .   . .  .  ..::.: 
NP_001 KVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDIANLPVPTIAAIDGL
            130       140       150       160       170       180  

     150       160       170       180       190       200         
pF1KE1 CPAGGCLVALTCDYRILADNPRYCIGLNETQLGIIAPFWLKDTLENTIGHRAAERALQLG
         .::  .::.:: :. :.. .  .:: ::.:.::      . :  .::   :.. .  .
NP_001 ALGGGLELALACDIRVAASSAK--MGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSA
            190       200         210       220       230       240

     210       220       230           240       250       260     
pF1KE1 LLFPPAEALQVGIVDQVVPEEQ----VQSTALSAIAQWMAIPDHARQLTKAMMRKATASR
        ..   ::  ::....:. ..:    .   ::.   ...     : ...:  . ..    
NP_001 RVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVD
              250       260       270       280       290       300

         270       280        290       300   
pF1KE1 LVTQRDADVQNFVSFI-SKDSIQKSLQMYLERLKEEKG 
       :::    .   ... : .:: ..  : .  .:  . :: 
NP_001 LVTGLAIEEACYAQTIPTKDRLEGLLAFKEKRPPRYKGE
              310       320       330         

>>NP_000173 (OMIM: 600890,609015,609016) trifunctional e  (763 aa)
 initn: 233 init1: 148 opt: 259  Z-score: 320.3  bits: 68.7 E(85289): 4.2e-11
Smith-Waterman score: 259; 29.1% identity (61.7% similar) in 196 aa overlap (40-227:27-222)

      10        20        30        40         50            60    
pF1KE1 PARVLLRAGARLPGAALGRTERAAGGGDGARRF-GSQRVLVEPDAGAGV----AVMKFKN
                                     : : ::. .:..   . ::    ::.....
NP_000     MVACRAIGILSRFSAFRILRSRGYICRNFTGSSALLTRTHINYGVKGDVAVVRINS
                   10        20        30        40        50      

             70        80        90       100       110        120 
pF1KE1 P--PVNSLSLEFLTELVISLEKLENDKSFRGVILTSDRPGVFSAGLDLTEMCG-RSPAHY
       :   ::.:: :. .:.   ....  . ..:...: :..:: : :: :.. . . ..  . 
NP_000 PNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLAACKTLQEV
         60        70        80        90       100       110      

             130       140       150       160       170       180 
pF1KE1 AGYWKAVQELWLRLYQSNLVLVSAINGACPAGGCLVALTCDYRILADNPRYCIGLNETQL
       .   . .:..  .: .:.  .:.::::.: .::  ::..:.::: . . .  .:  :. :
NP_000 TQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLL
        120       130       140       150       160       170      

             190       200       210       220       230       240 
pF1KE1 GIIAPFWLKDTLENTIGHRAAERALQLGLLFPPAEALQVGIVDQVVPEEQVQSTALSAIA
       : .      . : . .:  ::   .  :  .   .: ..:.:::.:              
NP_000 GALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEPLGPGLKPPEERT
        180       190       200       210       220       230      

             250       260       270       280       290       300 
pF1KE1 QWMAIPDHARQLTKAMMRKATASRLVTQRDADVQNFVSFISKDSIQKSLQMYLERLKEEK
                                                                   
NP_000 IEYLEEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTIPFVRQQVYKKVEEKVRKQTKG
        240       250       260       270       280       290      

>>XP_016870338 (OMIM: 250950,600529) PREDICTED: methylgl  (323 aa)
 initn: 268 init1: 179 opt: 248  Z-score: 312.3  bits: 65.9 E(85289): 1.2e-10
Smith-Waterman score: 259; 28.0% identity (55.2% similar) in 232 aa overlap (18-231:33-262)

                            10        20        30                 
pF1KE1              MALVASVRVPARVLLRAGARLPGAALGRTER----------AAGGGD
                                     : ::::.  ::             ::::  
XP_016 AAVAAAPGALGSLHAGGARLVAACSAWLCPGLRLPGSLAGRRAGPAIWAQGWVPAAGGPA
             10        20        30        40        50        60  

        40               50        60         70        80         
pF1KE1 GARRFGSQ-------RVLVEPDAGAGVAVMKF-KNPPVNSLSLEFLTELVISLEKLENDK
         : ..:.       ::    . . :..:. . .    :::: ...  :  ... :..::
XP_016 PKRGYSSEMKTEDELRVRHLEEENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDK
             70        80        90       100       110       120  

      90       100       110       120       130       140         
pF1KE1 SFRGVILTSDRPGVFSAGLDLTEMCGRSPAHYAGYWKAVQELWLRLYQSNLVLVSAINGA
       . : .:. :. ::.: :: :: :    : .. . . . .. .   . .  .  ..::.: 
XP_016 KVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDIANLPVPTIAAIDGL
            130       140       150       160       170       180  

     150       160       170       180       190       200         
pF1KE1 CPAGGCLVALTCDYRILADNPRYCIGLNETQLGIIAPFWLKDTLENTIGHRAAERALQLG
         .::  .::.:: :. :.. .  .:: ::.:.::      . :  .::   :.. .  .
XP_016 ALGGGLELALACDIRVAASSAK--MGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSA
            190       200         210       220       230       240

     210       220       230       240       250       260         
pF1KE1 LLFPPAEALQVGIVDQVVPEEQVQSTALSAIAQWMAIPDHARQLTKAMMRKATASRLVTQ
        ..   ::  ::....:. ..:                                      
XP_016 RVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMETI
              250       260       270       280       290       300

>>XP_005252123 (OMIM: 250950,600529) PREDICTED: methylgl  (349 aa)
 initn: 270 init1: 179 opt: 246  Z-score: 309.3  bits: 65.5 E(85289): 1.7e-10
Smith-Waterman score: 246; 25.8% identity (56.2% similar) in 240 aa overlap (68-302:111-348)

        40        50        60        70        80        90       
pF1KE1 GARRFGSQRVLVEPDAGAGVAVMKFKNPPVNSLSLEFLTELVISLEKLENDKSFRGVILT
                                     :::: ...  :  ... :..::. : .:. 
XP_005 HLEEENRDSSSMAADHYRIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIR
               90       100       110       120       130       140

       100       110       120       130       140       150       
pF1KE1 SDRPGVFSAGLDLTEMCGRSPAHYAGYWKAVQELWLRLYQSNLVLVSAINGACPAGGCLV
       :. ::.: :: :: :    : .. . . . .. .   . .  .  ..::.:   .::  .
XP_005 SEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLEL
              150       160       170       180       190       200

       160       170       180       190       200       210       
pF1KE1 ALTCDYRILADNPRYCIGLNETQLGIIAPFWLKDTLENTIGHRAAERALQLGLLFPPAEA
       ::.:: :. :.. .  .:: ::.:.::      . :  .::   :.. .  . ..   ::
XP_005 ALACDIRVAASSAK--MGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEA
              210         220       230       240       250        

       220       230           240       250       260       270   
pF1KE1 LQVGIVDQVVPEEQ----VQSTALSAIAQWMAIPDHARQLTKAMMRKATASRLVTQRDAD
         ::....:. ..:    .   ::.   ...     : ...:  . ..    :::    .
XP_005 KAVGLISHVLEQNQEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIE
      260       270       280       290       300       310        

           280        290       300   
pF1KE1 VQNFVSFI-SKDSIQKSLQMYLERLKEEKG 
          ... : .:: ..  : .  .:  . :: 
XP_005 EACYAQTIPTKDRLEGLLAFKEKRPPRYKGE
      320       330       340         

>>XP_005252126 (OMIM: 250950,600529) PREDICTED: methylgl  (298 aa)
 initn: 268 init1: 179 opt: 236  Z-score: 297.9  bits: 63.2 E(85289): 7.5e-10
Smith-Waterman score: 236; 29.3% identity (61.0% similar) in 164 aa overlap (68-231:111-272)

        40        50        60        70        80        90       
pF1KE1 GARRFGSQRVLVEPDAGAGVAVMKFKNPPVNSLSLEFLTELVISLEKLENDKSFRGVILT
                                     :::: ...  :  ... :..::. : .:. 
XP_005 HLEEENRDSSSMAADHYRIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIR
               90       100       110       120       130       140

       100       110       120       130       140       150       
pF1KE1 SDRPGVFSAGLDLTEMCGRSPAHYAGYWKAVQELWLRLYQSNLVLVSAINGACPAGGCLV
       :. ::.: :: :: :    : .. . . . .. .   . .  .  ..::.:   .::  .
XP_005 SEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLEL
              150       160       170       180       190       200

       160       170       180       190       200       210       
pF1KE1 ALTCDYRILADNPRYCIGLNETQLGIIAPFWLKDTLENTIGHRAAERALQLGLLFPPAEA
       ::.:: :. :.. .  .:: ::.:.::      . :  .::   :.. .  . ..   ::
XP_005 ALACDIRVAASSAK--MGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEA
              210         220       230       240       250        

       220       230       240       250       260       270       
pF1KE1 LQVGIVDQVVPEEQVQSTALSAIAQWMAIPDHARQLTKAMMRKATASRLVTQRDADVQNF
         ::....:. ..:                                              
XP_005 KAVGLISHVLEQNQEGDAAYRKALDLAREFLPQVKQIRRC                    
      260       270       280       290                            

>>XP_005252124 (OMIM: 250950,600529) PREDICTED: methylgl  (333 aa)
 initn: 268 init1: 179 opt: 236  Z-score: 297.1  bits: 63.2 E(85289): 8.2e-10
Smith-Waterman score: 236; 29.3% identity (61.0% similar) in 164 aa overlap (68-231:111-272)

        40        50        60        70        80        90       
pF1KE1 GARRFGSQRVLVEPDAGAGVAVMKFKNPPVNSLSLEFLTELVISLEKLENDKSFRGVILT
                                     :::: ...  :  ... :..::. : .:. 
XP_005 HLEEENRDSSSMAADHYRIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIR
               90       100       110       120       130       140

       100       110       120       130       140       150       
pF1KE1 SDRPGVFSAGLDLTEMCGRSPAHYAGYWKAVQELWLRLYQSNLVLVSAINGACPAGGCLV
       :. ::.: :: :: :    : .. . . . .. .   . .  .  ..::.:   .::  .
XP_005 SEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLEL
              150       160       170       180       190       200

       160       170       180       190       200       210       
pF1KE1 ALTCDYRILADNPRYCIGLNETQLGIIAPFWLKDTLENTIGHRAAERALQLGLLFPPAEA
       ::.:: :. :.. .  .:: ::.:.::      . :  .::   :.. .  . ..   ::
XP_005 ALACDIRVAASSAK--MGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEA
              210         220       230       240       250        

       220       230       240       250       260       270       
pF1KE1 LQVGIVDQVVPEEQVQSTALSAIAQWMAIPDHARQLTKAMMRKATASRLVTQRDADVQNF
         ::....:. ..:                                              
XP_005 KAVGLISHVLEQNQEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMETIPTKDRLEG
      260       270       280       290       300       310        

>>XP_011517104 (OMIM: 250950,600529) PREDICTED: methylgl  (230 aa)
 initn: 207 init1: 150 opt: 227  Z-score: 288.4  bits: 61.0 E(85289): 2.5e-09
Smith-Waterman score: 227; 25.1% identity (55.9% similar) in 227 aa overlap (81-302:5-229)

               60        70        80        90       100       110
pF1KE1 PDAGAGVAVMKFKNPPVNSLSLEFLTELVISLEKLENDKSFRGVILTSDRPGVFSAGLDL
                                     ... :..::. : .:. :. ::.: :: ::
XP_011                           MLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADL
                                         10        20        30    

              120       130       140       150       160       170
pF1KE1 TEMCGRSPAHYAGYWKAVQELWLRLYQSNLVLVSAINGACPAGGCLVALTCDYRILADNP
        :    : .. . . . .. .   . .  .  ..::.:   .::  .::.:: :. :.. 
XP_011 KERAKMSSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSA
           40        50        60        70        80        90    

              180       190       200       210       220       230
pF1KE1 RYCIGLNETQLGIIAPFWLKDTLENTIGHRAAERALQLGLLFPPAEALQVGIVDQVVPEE
       .  .:: ::.:.::      . :  .::   :.. .  . ..   ::  ::....:. ..
XP_011 K--MGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQN
            100       110       120       130       140       150  

                  240       250       260       270       280      
pF1KE1 Q----VQSTALSAIAQWMAIPDHARQLTKAMMRKATASRLVTQRDADVQNFVSFI-SKDS
       :    .   ::.   ...     : ...:  . ..    :::    .   ... : .:: 
XP_011 QEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDR
            160       170       180       190       200       210  

         290       300   
pF1KE1 IQKSLQMYLERLKEEKG 
       ..  : .  .:  . :: 
XP_011 LEGLLAFKEKRPPRYKGE
            220       230

>>XP_016870339 (OMIM: 250950,600529) PREDICTED: methylgl  (230 aa)
 initn: 207 init1: 150 opt: 227  Z-score: 288.4  bits: 61.0 E(85289): 2.5e-09
Smith-Waterman score: 227; 25.1% identity (55.9% similar) in 227 aa overlap (81-302:5-229)

               60        70        80        90       100       110
pF1KE1 PDAGAGVAVMKFKNPPVNSLSLEFLTELVISLEKLENDKSFRGVILTSDRPGVFSAGLDL
                                     ... :..::. : .:. :. ::.: :: ::
XP_016                           MLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADL
                                         10        20        30    

              120       130       140       150       160       170
pF1KE1 TEMCGRSPAHYAGYWKAVQELWLRLYQSNLVLVSAINGACPAGGCLVALTCDYRILADNP
        :    : .. . . . .. .   . .  .  ..::.:   .::  .::.:: :. :.. 
XP_016 KERAKMSSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSA
           40        50        60        70        80        90    

              180       190       200       210       220       230
pF1KE1 RYCIGLNETQLGIIAPFWLKDTLENTIGHRAAERALQLGLLFPPAEALQVGIVDQVVPEE
       .  .:: ::.:.::      . :  .::   :.. .  . ..   ::  ::....:. ..
XP_016 K--MGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQN
            100       110       120       130       140       150  

                  240       250       260       270       280      
pF1KE1 Q----VQSTALSAIAQWMAIPDHARQLTKAMMRKATASRLVTQRDADVQNFVSFI-SKDS
       :    .   ::.   ...     : ...:  . ..    :::    .   ... : .:: 
XP_016 QEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDR
            160       170       180       190       200       210  

         290       300   
pF1KE1 IQKSLQMYLERLKEEKG 
       ..  : .  .:  . :: 
XP_016 LEGLLAFKEKRPPRYKGE
            220       230




302 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 20:16:23 2016 done: Sun Nov  6 20:16:24 2016
 Total Scan time:  7.860 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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