Result of FASTA (omim) for
pF1KE1023
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1023, 774 aa
1>>>pF1KE1023 774 - 774 aa - 774 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 18.4935+/-0.000467; mu= -44.4790+/- 0.029
mean_var=682.5597+/-140.961, 0's: 0 Z-trim(124.3): 22 B-trim: 0 in 0/62
Lambda= 0.049091
statistics sampled from 45606 (45632) to 45606 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.801), E-opt: 0.2 (0.535), width: 16
Scan time: 12.490
The best scores are: opt bits E(85289)
NP_005482 (OMIM: 300120,300758) mastermind-like do ( 774) 5270 388.6 5.3e-107
XP_006724865 (OMIM: 300120,300758) PREDICTED: mast ( 774) 5270 388.6 5.3e-107
XP_006724866 (OMIM: 300120,300758) PREDICTED: mast ( 749) 4875 360.6 1.4e-98
NP_001170937 (OMIM: 300120,300758) mastermind-like ( 749) 4875 360.6 1.4e-98
XP_016884677 (OMIM: 300120,300758) PREDICTED: mast ( 749) 4875 360.6 1.4e-98
XP_011529397 (OMIM: 300120,300758) PREDICTED: mast ( 733) 4312 320.8 1.3e-86
XP_011529395 (OMIM: 300120,300758) PREDICTED: mast (1023) 4310 320.7 2e-86
XP_011529394 (OMIM: 300120,300758) PREDICTED: mast (1023) 4310 320.7 2e-86
XP_016884678 (OMIM: 300120,300758) PREDICTED: mast ( 708) 3917 292.8 3.4e-78
NP_001170936 (OMIM: 300120,300758) mastermind-like ( 998) 3915 292.7 5.2e-78
XP_011541327 (OMIM: 607537) PREDICTED: mastermind- ( 735) 385 42.6 0.0071
>>NP_005482 (OMIM: 300120,300758) mastermind-like domain (774 aa)
initn: 5270 init1: 5270 opt: 5270 Z-score: 2042.0 bits: 388.6 E(85289): 5.3e-107
Smith-Waterman score: 5270; 99.9% identity (100.0% similar) in 774 aa overlap (1-774:1-774)
10 20 30 40 50 60
pF1KE1 MDDWKSRLVIKSMLPHFAMVGNRQEPRKLQESGKKPSWMEEEDLSFLYKSSPGRKHQGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MDDWKSRLVIKSMLPHFAMVGNRQEPRKLQESGKKPSWMEEEDLSFLYKSSPGRKHQGTV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KRRQEEDHFQFPDMADGGYPNKIKRPCLEDVTLAMGPGAHPSTACAELQVPPLTINPSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KRRQEEDHFQFPDMADGGYPNKIKRPCLEDVTLAMGPGAHPSTACAELQVPPLTINPSPA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AMGVAGQSLLLENNPMNGNIMGSPFVVPQTTEVGLKGPTVPYYEKINSVPAVDQELQELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AMGVAGQSLLLENNPMNGNIMGSPFVVPQTTEVGLKGPTVPYYEKINSVPAVDQELQELL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 EELTKIQDPSPNELDLEKILGTKPEEPLVLDHPQATLSTTPKPSVQMSHLESLASSKEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EELTKIQDPSPNELDLEKILGTKPEEPLVLDHPQATLSTTPKPSVQMSHLESLASSKEFA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 SSCSQVTGMSLQIPSSSTGISYSIPSTSKQIVSPSSSMAQSKSQVQAMLPVALPPLPVPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SSCSQVTGMSLQIPSSSTGISYSIPSTSKQIVSPSSSMAQSKSQVQAMLPVALPPLPVPQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 WHHAHQLKALAASKQGSATKQQGPTPSWSGLPPPGLSPPYRPVPSPHPPPLPLPPPPPPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 WHHAHQLKALAASKQGSATKQQGPTPSWSGLPPPGLSPPYRPVPSPHPPPLPLPPPPPPF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 SPQSLMVSCMSSNTLSGSTLRGSPNALLSSMTSSSNAALGPAMPYAPEKLPSPALTQQPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SPQSLMVSCMSSNTLSGSTLRGSPNALLSSMTSSSNAALGPAMPYAPEKLPSPALTQQPQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 FGPQSSILANLMSSTIKTPQGHLMSALPASNPGPSPPYRPEKLSSPGLPQQSFTPQCSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FGPQSSILANLMSSTIKTPQGHLMSALPASNPGPSPPYRPEKLSSPGLPQQSFTPQCSLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 RSLTPTSNLLSQQQQQQQQQQQANVIFKPISSNSSKTLSMIMQQGMASSSPGATEPFTFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RSLTPTSNLLSQQQQQQQQQQQANVIFKPISSNSSKTLSMIMQQGMASSSPGATEPFTFG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 NTKPLSHFVSEPGPQKMPSMPTTSRQPSLLHYLQQPTPTQASSATASSTATATLQLQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NTKPLSHFVSEPGPQKMPSMPTTSRQPSLLHYLQQPTPTQASSATASSTATATLQLQQQQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 QQQQQQPDHSSFLLQQMMQQPQRFQRSVASDSMPALPRQGCCHLFAWTSAASSVKPQHQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QQQQQQPDHSSFLLQQMMQQPQRFQRSVASDSMPALPRQGCCHLFAWTSAASSVKPQHQH
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 GSSFTSRQDPQPGDVSPSNITHVDKACKLGEARHPQVSLGRQPPSCQALGSESFLPGSSF
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GNSFTSRQDPQPGDVSPSNITHVDKACKLGEARHPQVSLGRQPPSCQALGSESFLPGSSF
670 680 690 700 710 720
730 740 750 760 770
pF1KE1 AHELARVTSSYSTSEAAPWGSWDPKAWRQVPAPLLPSCDATARGTEIRSYGNDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AHELARVTSSYSTSEAAPWGSWDPKAWRQVPAPLLPSCDATARGTEIRSYGNDP
730 740 750 760 770
>>XP_006724865 (OMIM: 300120,300758) PREDICTED: mastermi (774 aa)
initn: 5270 init1: 5270 opt: 5270 Z-score: 2042.0 bits: 388.6 E(85289): 5.3e-107
Smith-Waterman score: 5270; 99.9% identity (100.0% similar) in 774 aa overlap (1-774:1-774)
10 20 30 40 50 60
pF1KE1 MDDWKSRLVIKSMLPHFAMVGNRQEPRKLQESGKKPSWMEEEDLSFLYKSSPGRKHQGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MDDWKSRLVIKSMLPHFAMVGNRQEPRKLQESGKKPSWMEEEDLSFLYKSSPGRKHQGTV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KRRQEEDHFQFPDMADGGYPNKIKRPCLEDVTLAMGPGAHPSTACAELQVPPLTINPSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KRRQEEDHFQFPDMADGGYPNKIKRPCLEDVTLAMGPGAHPSTACAELQVPPLTINPSPA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AMGVAGQSLLLENNPMNGNIMGSPFVVPQTTEVGLKGPTVPYYEKINSVPAVDQELQELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AMGVAGQSLLLENNPMNGNIMGSPFVVPQTTEVGLKGPTVPYYEKINSVPAVDQELQELL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 EELTKIQDPSPNELDLEKILGTKPEEPLVLDHPQATLSTTPKPSVQMSHLESLASSKEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EELTKIQDPSPNELDLEKILGTKPEEPLVLDHPQATLSTTPKPSVQMSHLESLASSKEFA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 SSCSQVTGMSLQIPSSSTGISYSIPSTSKQIVSPSSSMAQSKSQVQAMLPVALPPLPVPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSCSQVTGMSLQIPSSSTGISYSIPSTSKQIVSPSSSMAQSKSQVQAMLPVALPPLPVPQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 WHHAHQLKALAASKQGSATKQQGPTPSWSGLPPPGLSPPYRPVPSPHPPPLPLPPPPPPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WHHAHQLKALAASKQGSATKQQGPTPSWSGLPPPGLSPPYRPVPSPHPPPLPLPPPPPPF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 SPQSLMVSCMSSNTLSGSTLRGSPNALLSSMTSSSNAALGPAMPYAPEKLPSPALTQQPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SPQSLMVSCMSSNTLSGSTLRGSPNALLSSMTSSSNAALGPAMPYAPEKLPSPALTQQPQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 FGPQSSILANLMSSTIKTPQGHLMSALPASNPGPSPPYRPEKLSSPGLPQQSFTPQCSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FGPQSSILANLMSSTIKTPQGHLMSALPASNPGPSPPYRPEKLSSPGLPQQSFTPQCSLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 RSLTPTSNLLSQQQQQQQQQQQANVIFKPISSNSSKTLSMIMQQGMASSSPGATEPFTFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RSLTPTSNLLSQQQQQQQQQQQANVIFKPISSNSSKTLSMIMQQGMASSSPGATEPFTFG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 NTKPLSHFVSEPGPQKMPSMPTTSRQPSLLHYLQQPTPTQASSATASSTATATLQLQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NTKPLSHFVSEPGPQKMPSMPTTSRQPSLLHYLQQPTPTQASSATASSTATATLQLQQQQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 QQQQQQPDHSSFLLQQMMQQPQRFQRSVASDSMPALPRQGCCHLFAWTSAASSVKPQHQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QQQQQQPDHSSFLLQQMMQQPQRFQRSVASDSMPALPRQGCCHLFAWTSAASSVKPQHQH
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 GSSFTSRQDPQPGDVSPSNITHVDKACKLGEARHPQVSLGRQPPSCQALGSESFLPGSSF
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GNSFTSRQDPQPGDVSPSNITHVDKACKLGEARHPQVSLGRQPPSCQALGSESFLPGSSF
670 680 690 700 710 720
730 740 750 760 770
pF1KE1 AHELARVTSSYSTSEAAPWGSWDPKAWRQVPAPLLPSCDATARGTEIRSYGNDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AHELARVTSSYSTSEAAPWGSWDPKAWRQVPAPLLPSCDATARGTEIRSYGNDP
730 740 750 760 770
>>XP_006724866 (OMIM: 300120,300758) PREDICTED: mastermi (749 aa)
initn: 4874 init1: 4874 opt: 4875 Z-score: 1891.0 bits: 360.6 E(85289): 1.4e-98
Smith-Waterman score: 5032; 96.6% identity (96.8% similar) in 774 aa overlap (1-774:1-749)
10 20 30 40 50 60
pF1KE1 MDDWKSRLVIKSMLPHFAMVGNRQEPRKLQESGKKPSWMEEEDLSFLYKSSPGRKHQGTV
::::::::::::::::::::::::::::::::: ::
XP_006 MDDWKSRLVIKSMLPHFAMVGNRQEPRKLQESG-------------------------TV
10 20 30
70 80 90 100 110 120
pF1KE1 KRRQEEDHFQFPDMADGGYPNKIKRPCLEDVTLAMGPGAHPSTACAELQVPPLTINPSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KRRQEEDHFQFPDMADGGYPNKIKRPCLEDVTLAMGPGAHPSTACAELQVPPLTINPSPA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 AMGVAGQSLLLENNPMNGNIMGSPFVVPQTTEVGLKGPTVPYYEKINSVPAVDQELQELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AMGVAGQSLLLENNPMNGNIMGSPFVVPQTTEVGLKGPTVPYYEKINSVPAVDQELQELL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 EELTKIQDPSPNELDLEKILGTKPEEPLVLDHPQATLSTTPKPSVQMSHLESLASSKEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EELTKIQDPSPNELDLEKILGTKPEEPLVLDHPQATLSTTPKPSVQMSHLESLASSKEFA
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE1 SSCSQVTGMSLQIPSSSTGISYSIPSTSKQIVSPSSSMAQSKSQVQAMLPVALPPLPVPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSCSQVTGMSLQIPSSSTGISYSIPSTSKQIVSPSSSMAQSKSQVQAMLPVALPPLPVPQ
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 WHHAHQLKALAASKQGSATKQQGPTPSWSGLPPPGLSPPYRPVPSPHPPPLPLPPPPPPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WHHAHQLKALAASKQGSATKQQGPTPSWSGLPPPGLSPPYRPVPSPHPPPLPLPPPPPPF
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE1 SPQSLMVSCMSSNTLSGSTLRGSPNALLSSMTSSSNAALGPAMPYAPEKLPSPALTQQPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SPQSLMVSCMSSNTLSGSTLRGSPNALLSSMTSSSNAALGPAMPYAPEKLPSPALTQQPQ
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE1 FGPQSSILANLMSSTIKTPQGHLMSALPASNPGPSPPYRPEKLSSPGLPQQSFTPQCSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FGPQSSILANLMSSTIKTPQGHLMSALPASNPGPSPPYRPEKLSSPGLPQQSFTPQCSLI
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE1 RSLTPTSNLLSQQQQQQQQQQQANVIFKPISSNSSKTLSMIMQQGMASSSPGATEPFTFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RSLTPTSNLLSQQQQQQQQQQQANVIFKPISSNSSKTLSMIMQQGMASSSPGATEPFTFG
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE1 NTKPLSHFVSEPGPQKMPSMPTTSRQPSLLHYLQQPTPTQASSATASSTATATLQLQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NTKPLSHFVSEPGPQKMPSMPTTSRQPSLLHYLQQPTPTQASSATASSTATATLQLQQQQ
520 530 540 550 560 570
610 620 630 640 650 660
pF1KE1 QQQQQQPDHSSFLLQQMMQQPQRFQRSVASDSMPALPRQGCCHLFAWTSAASSVKPQHQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QQQQQQPDHSSFLLQQMMQQPQRFQRSVASDSMPALPRQGCCHLFAWTSAASSVKPQHQH
580 590 600 610 620 630
670 680 690 700 710 720
pF1KE1 GSSFTSRQDPQPGDVSPSNITHVDKACKLGEARHPQVSLGRQPPSCQALGSESFLPGSSF
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GNSFTSRQDPQPGDVSPSNITHVDKACKLGEARHPQVSLGRQPPSCQALGSESFLPGSSF
640 650 660 670 680 690
730 740 750 760 770
pF1KE1 AHELARVTSSYSTSEAAPWGSWDPKAWRQVPAPLLPSCDATARGTEIRSYGNDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AHELARVTSSYSTSEAAPWGSWDPKAWRQVPAPLLPSCDATARGTEIRSYGNDP
700 710 720 730 740
>>NP_001170937 (OMIM: 300120,300758) mastermind-like dom (749 aa)
initn: 4874 init1: 4874 opt: 4875 Z-score: 1891.0 bits: 360.6 E(85289): 1.4e-98
Smith-Waterman score: 5032; 96.6% identity (96.8% similar) in 774 aa overlap (1-774:1-749)
10 20 30 40 50 60
pF1KE1 MDDWKSRLVIKSMLPHFAMVGNRQEPRKLQESGKKPSWMEEEDLSFLYKSSPGRKHQGTV
::::::::::::::::::::::::::::::::: ::
NP_001 MDDWKSRLVIKSMLPHFAMVGNRQEPRKLQESG-------------------------TV
10 20 30
70 80 90 100 110 120
pF1KE1 KRRQEEDHFQFPDMADGGYPNKIKRPCLEDVTLAMGPGAHPSTACAELQVPPLTINPSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRRQEEDHFQFPDMADGGYPNKIKRPCLEDVTLAMGPGAHPSTACAELQVPPLTINPSPA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 AMGVAGQSLLLENNPMNGNIMGSPFVVPQTTEVGLKGPTVPYYEKINSVPAVDQELQELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AMGVAGQSLLLENNPMNGNIMGSPFVVPQTTEVGLKGPTVPYYEKINSVPAVDQELQELL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 EELTKIQDPSPNELDLEKILGTKPEEPLVLDHPQATLSTTPKPSVQMSHLESLASSKEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EELTKIQDPSPNELDLEKILGTKPEEPLVLDHPQATLSTTPKPSVQMSHLESLASSKEFA
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE1 SSCSQVTGMSLQIPSSSTGISYSIPSTSKQIVSPSSSMAQSKSQVQAMLPVALPPLPVPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSCSQVTGMSLQIPSSSTGISYSIPSTSKQIVSPSSSMAQSKSQVQAMLPVALPPLPVPQ
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 WHHAHQLKALAASKQGSATKQQGPTPSWSGLPPPGLSPPYRPVPSPHPPPLPLPPPPPPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WHHAHQLKALAASKQGSATKQQGPTPSWSGLPPPGLSPPYRPVPSPHPPPLPLPPPPPPF
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE1 SPQSLMVSCMSSNTLSGSTLRGSPNALLSSMTSSSNAALGPAMPYAPEKLPSPALTQQPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPQSLMVSCMSSNTLSGSTLRGSPNALLSSMTSSSNAALGPAMPYAPEKLPSPALTQQPQ
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE1 FGPQSSILANLMSSTIKTPQGHLMSALPASNPGPSPPYRPEKLSSPGLPQQSFTPQCSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGPQSSILANLMSSTIKTPQGHLMSALPASNPGPSPPYRPEKLSSPGLPQQSFTPQCSLI
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE1 RSLTPTSNLLSQQQQQQQQQQQANVIFKPISSNSSKTLSMIMQQGMASSSPGATEPFTFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSLTPTSNLLSQQQQQQQQQQQANVIFKPISSNSSKTLSMIMQQGMASSSPGATEPFTFG
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE1 NTKPLSHFVSEPGPQKMPSMPTTSRQPSLLHYLQQPTPTQASSATASSTATATLQLQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTKPLSHFVSEPGPQKMPSMPTTSRQPSLLHYLQQPTPTQASSATASSTATATLQLQQQQ
520 530 540 550 560 570
610 620 630 640 650 660
pF1KE1 QQQQQQPDHSSFLLQQMMQQPQRFQRSVASDSMPALPRQGCCHLFAWTSAASSVKPQHQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQQQQQPDHSSFLLQQMMQQPQRFQRSVASDSMPALPRQGCCHLFAWTSAASSVKPQHQH
580 590 600 610 620 630
670 680 690 700 710 720
pF1KE1 GSSFTSRQDPQPGDVSPSNITHVDKACKLGEARHPQVSLGRQPPSCQALGSESFLPGSSF
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNSFTSRQDPQPGDVSPSNITHVDKACKLGEARHPQVSLGRQPPSCQALGSESFLPGSSF
640 650 660 670 680 690
730 740 750 760 770
pF1KE1 AHELARVTSSYSTSEAAPWGSWDPKAWRQVPAPLLPSCDATARGTEIRSYGNDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHELARVTSSYSTSEAAPWGSWDPKAWRQVPAPLLPSCDATARGTEIRSYGNDP
700 710 720 730 740
>>XP_016884677 (OMIM: 300120,300758) PREDICTED: mastermi (749 aa)
initn: 4874 init1: 4874 opt: 4875 Z-score: 1891.0 bits: 360.6 E(85289): 1.4e-98
Smith-Waterman score: 5032; 96.6% identity (96.8% similar) in 774 aa overlap (1-774:1-749)
10 20 30 40 50 60
pF1KE1 MDDWKSRLVIKSMLPHFAMVGNRQEPRKLQESGKKPSWMEEEDLSFLYKSSPGRKHQGTV
::::::::::::::::::::::::::::::::: ::
XP_016 MDDWKSRLVIKSMLPHFAMVGNRQEPRKLQESG-------------------------TV
10 20 30
70 80 90 100 110 120
pF1KE1 KRRQEEDHFQFPDMADGGYPNKIKRPCLEDVTLAMGPGAHPSTACAELQVPPLTINPSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRRQEEDHFQFPDMADGGYPNKIKRPCLEDVTLAMGPGAHPSTACAELQVPPLTINPSPA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 AMGVAGQSLLLENNPMNGNIMGSPFVVPQTTEVGLKGPTVPYYEKINSVPAVDQELQELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AMGVAGQSLLLENNPMNGNIMGSPFVVPQTTEVGLKGPTVPYYEKINSVPAVDQELQELL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 EELTKIQDPSPNELDLEKILGTKPEEPLVLDHPQATLSTTPKPSVQMSHLESLASSKEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EELTKIQDPSPNELDLEKILGTKPEEPLVLDHPQATLSTTPKPSVQMSHLESLASSKEFA
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE1 SSCSQVTGMSLQIPSSSTGISYSIPSTSKQIVSPSSSMAQSKSQVQAMLPVALPPLPVPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSCSQVTGMSLQIPSSSTGISYSIPSTSKQIVSPSSSMAQSKSQVQAMLPVALPPLPVPQ
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 WHHAHQLKALAASKQGSATKQQGPTPSWSGLPPPGLSPPYRPVPSPHPPPLPLPPPPPPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WHHAHQLKALAASKQGSATKQQGPTPSWSGLPPPGLSPPYRPVPSPHPPPLPLPPPPPPF
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE1 SPQSLMVSCMSSNTLSGSTLRGSPNALLSSMTSSSNAALGPAMPYAPEKLPSPALTQQPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPQSLMVSCMSSNTLSGSTLRGSPNALLSSMTSSSNAALGPAMPYAPEKLPSPALTQQPQ
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE1 FGPQSSILANLMSSTIKTPQGHLMSALPASNPGPSPPYRPEKLSSPGLPQQSFTPQCSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGPQSSILANLMSSTIKTPQGHLMSALPASNPGPSPPYRPEKLSSPGLPQQSFTPQCSLI
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE1 RSLTPTSNLLSQQQQQQQQQQQANVIFKPISSNSSKTLSMIMQQGMASSSPGATEPFTFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSLTPTSNLLSQQQQQQQQQQQANVIFKPISSNSSKTLSMIMQQGMASSSPGATEPFTFG
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE1 NTKPLSHFVSEPGPQKMPSMPTTSRQPSLLHYLQQPTPTQASSATASSTATATLQLQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTKPLSHFVSEPGPQKMPSMPTTSRQPSLLHYLQQPTPTQASSATASSTATATLQLQQQQ
520 530 540 550 560 570
610 620 630 640 650 660
pF1KE1 QQQQQQPDHSSFLLQQMMQQPQRFQRSVASDSMPALPRQGCCHLFAWTSAASSVKPQHQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQQQQQPDHSSFLLQQMMQQPQRFQRSVASDSMPALPRQGCCHLFAWTSAASSVKPQHQH
580 590 600 610 620 630
670 680 690 700 710 720
pF1KE1 GSSFTSRQDPQPGDVSPSNITHVDKACKLGEARHPQVSLGRQPPSCQALGSESFLPGSSF
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNSFTSRQDPQPGDVSPSNITHVDKACKLGEARHPQVSLGRQPPSCQALGSESFLPGSSF
640 650 660 670 680 690
730 740 750 760 770
pF1KE1 AHELARVTSSYSTSEAAPWGSWDPKAWRQVPAPLLPSCDATARGTEIRSYGNDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHELARVTSSYSTSEAAPWGSWDPKAWRQVPAPLLPSCDATARGTEIRSYGNDP
700 710 720 730 740
>>XP_011529397 (OMIM: 300120,300758) PREDICTED: mastermi (733 aa)
initn: 4960 init1: 4310 opt: 4312 Z-score: 1675.7 bits: 320.8 E(85289): 1.3e-86
Smith-Waterman score: 4882; 94.7% identity (94.7% similar) in 774 aa overlap (1-774:1-733)
10 20 30 40 50 60
pF1KE1 MDDWKSRLVIKSMLPHFAMVGNRQEPRKLQESGKKPSWMEEEDLSFLYKSSPGRKHQGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDDWKSRLVIKSMLPHFAMVGNRQEPRKLQESGKKPSWMEEEDLSFLYKSSPGRKHQGTV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KRRQEEDHFQFPDMADGGYPNKIKRPCLEDVTLAMGPGAHPSTACAELQVPPLTINPSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRRQEEDHFQFPDMADGGYPNKIKRPCLEDVTLAMGPGAHPSTACAELQVPPLTINPSPA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AMGVAGQSLLLENNPMNGNIMGSPFVVPQTTEVGLKGPTVPYYEKINSVPAVDQELQELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AMGVAGQSLLLENNPMNGNIMGSPFVVPQTTEVGLKGPTVPYYEKINSVPAVDQELQELL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 EELTKIQDPSPNELDLEKILGTKPEEPLVLDHPQATLSTTPKPSVQMSHLESLASSKEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELTKIQDPSPNELDLEKILGTKPEEPLVLDHPQATLSTTPKPSVQMSHLESLASSKEFA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 SSCSQVTGMSLQIPSSSTGISYSIPSTSKQIVSPSSSMAQSKSQVQAMLPVALPPLPVPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSCSQVTGMSLQIPSSSTGISYSIPSTSKQIVSPSSSMAQSKSQVQAMLPVALPPLPVPQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 WHHAHQLKALAASKQGSATKQQGPTPSWSGLPPPGLSPPYRPVPSPHPPPLPLPPPPPPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WHHAHQLKALAASKQGSATKQQGPTPSWSGLPPPGLSPPYRPVPSPHPPPLPLPPPPPPF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 SPQSLMVSCMSSNTLSGSTLRGSPNALLSSMTSSSNAALGPAMPYAPEKLPSPALTQQPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPQSLMVSCMSSNTLSGSTLRGSPNALLSSMTSSSNAALGPAMPYAPEKLPSPALTQQPQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 FGPQSSILANLMSSTIKTPQGHLMSALPASNPGPSPPYRPEKLSSPGLPQQSFTPQCSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGPQSSILANLMSSTIKTPQGHLMSALPASNPGPSPPYRPEKLSSPGLPQQSFTPQCSLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 RSLTPTSNLLSQQQQQQQQQQQANVIFKPISSNSSKTLSMIMQQGMASSSPGATEPFTFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSLTPTSNLLSQQQQQQQQQQQANVIFKPISSNSSKTLSMIMQQGMASSSPGATEPFTFG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 NTKPLSHFVSEPGPQKMPSMPTTSRQPSLLHYLQQPTPTQASSATASSTATATLQLQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTKPLSHFVSEPGPQKMPSMPTTSRQPSLLHYLQQPTPTQASSATASSTATATLQLQQQQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 QQQQQQPDHSSFLLQQMMQQPQRFQRSVASDSMPALPRQGCCHLFAWTSAASSVKPQHQH
:::::::::::::::::::::::::::::::::::::::
XP_011 QQQQQQPDHSSFLLQQMMQQPQRFQRSVASDSMPALPRQ---------------------
610 620 630
670 680 690 700 710 720
pF1KE1 GSSFTSRQDPQPGDVSPSNITHVDKACKLGEARHPQVSLGRQPPSCQALGSESFLPGSSF
::::::::::::::::::::::::::::::::::::::::
XP_011 --------------------THVDKACKLGEARHPQVSLGRQPPSCQALGSESFLPGSSF
640 650 660 670
730 740 750 760 770
pF1KE1 AHELARVTSSYSTSEAAPWGSWDPKAWRQVPAPLLPSCDATARGTEIRSYGNDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHELARVTSSYSTSEAAPWGSWDPKAWRQVPAPLLPSCDATARGTEIRSYGNDP
680 690 700 710 720 730
>>XP_011529395 (OMIM: 300120,300758) PREDICTED: mastermi (1023 aa)
initn: 4310 init1: 4310 opt: 4310 Z-score: 1672.6 bits: 320.7 E(85289): 2e-86
Smith-Waterman score: 4318; 91.4% identity (94.8% similar) in 717 aa overlap (1-717:1-705)
10 20 30 40 50 60
pF1KE1 MDDWKSRLVIKSMLPHFAMVGNRQEPRKLQESGKKPSWMEEEDLSFLYKSSPGRKHQGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDDWKSRLVIKSMLPHFAMVGNRQEPRKLQESGKKPSWMEEEDLSFLYKSSPGRKHQGTV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KRRQEEDHFQFPDMADGGYPNKIKRPCLEDVTLAMGPGAHPSTACAELQVPPLTINPSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRRQEEDHFQFPDMADGGYPNKIKRPCLEDVTLAMGPGAHPSTACAELQVPPLTINPSPA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AMGVAGQSLLLENNPMNGNIMGSPFVVPQTTEVGLKGPTVPYYEKINSVPAVDQELQELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AMGVAGQSLLLENNPMNGNIMGSPFVVPQTTEVGLKGPTVPYYEKINSVPAVDQELQELL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 EELTKIQDPSPNELDLEKILGTKPEEPLVLDHPQATLSTTPKPSVQMSHLESLASSKEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELTKIQDPSPNELDLEKILGTKPEEPLVLDHPQATLSTTPKPSVQMSHLESLASSKEFA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 SSCSQVTGMSLQIPSSSTGISYSIPSTSKQIVSPSSSMAQSKSQVQAMLPVALPPLPVPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSCSQVTGMSLQIPSSSTGISYSIPSTSKQIVSPSSSMAQSKSQVQAMLPVALPPLPVPQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 WHHAHQLKALAASKQGSATKQQGPTPSWSGLPPPGLSPPYRPVPSPHPPPLPLPPPPPPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WHHAHQLKALAASKQGSATKQQGPTPSWSGLPPPGLSPPYRPVPSPHPPPLPLPPPPPPF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 SPQSLMVSCMSSNTLSGSTLRGSPNALLSSMTSSSNAALGPAMPYAPEKLPSPALTQQPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPQSLMVSCMSSNTLSGSTLRGSPNALLSSMTSSSNAALGPAMPYAPEKLPSPALTQQPQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 FGPQSSILANLMSSTIKTPQGHLMSALPASNPGPSPPYRPEKLSSPGLPQQSFTPQCSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGPQSSILANLMSSTIKTPQGHLMSALPASNPGPSPPYRPEKLSSPGLPQQSFTPQCSLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 RSLTPTSNLLSQQQQQQQQQQQANVIFKPISSNSSKTLSMIMQQGMASSSPGATEPFTFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSLTPTSNLLSQQQQQQQQQQQANVIFKPISSNSSKTLSMIMQQGMASSSPGATEPFTFG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 NTKPLSHFVSEPGPQKMPSMPTTSRQPSLLHYLQQPTPTQASSATASSTATATLQLQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTKPLSHFVSEPGPQKMPSMPTTSRQPSLLHYLQQPTPTQASSATASSTATATLQLQQQQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 QQQQQQPDHSSFLLQQMMQQPQRFQRSVASDSMPALPRQGCCHLFAWTSAASSVKPQHQH
::::::::::::::::::::::::::::::::::::::: . :. .. :..:.
XP_011 QQQQQQPDHSSFLLQQMMQQPQRFQRSVASDSMPALPRQQEEQ----RSGLMAMTPERQN
610 620 630 640 650
670 680 690 700 710 720
pF1KE1 GSSFTSRQDPQPGDVSPSNITHVDKACKLGEARHPQVSLGRQPPSCQALGSESFLPGSSF
.. :.: .: .. ..: . :. .: :. : .:: .: .... ::
XP_011 --AYISQQ-MSPFEAVQEQVT---SKCSRIKASPPS-SKHLMPPRT-GLLQNNLSPGMIP
660 670 680 690 700
730 740 750 760 770
pF1KE1 AHELARVTSSYSTSEAAPWGSWDPKAWRQVPAPLLPSCDATARGTEIRSYGNDP
XP_011 LTRHQSCEGMGVISPTLGKRQGIFTSSPQCPILSHSGQTPLGRLDSVCQHMQSPKATPPE
710 720 730 740 750 760
>>XP_011529394 (OMIM: 300120,300758) PREDICTED: mastermi (1023 aa)
initn: 4310 init1: 4310 opt: 4310 Z-score: 1672.6 bits: 320.7 E(85289): 2e-86
Smith-Waterman score: 4318; 91.4% identity (94.8% similar) in 717 aa overlap (1-717:1-705)
10 20 30 40 50 60
pF1KE1 MDDWKSRLVIKSMLPHFAMVGNRQEPRKLQESGKKPSWMEEEDLSFLYKSSPGRKHQGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDDWKSRLVIKSMLPHFAMVGNRQEPRKLQESGKKPSWMEEEDLSFLYKSSPGRKHQGTV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KRRQEEDHFQFPDMADGGYPNKIKRPCLEDVTLAMGPGAHPSTACAELQVPPLTINPSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRRQEEDHFQFPDMADGGYPNKIKRPCLEDVTLAMGPGAHPSTACAELQVPPLTINPSPA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AMGVAGQSLLLENNPMNGNIMGSPFVVPQTTEVGLKGPTVPYYEKINSVPAVDQELQELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AMGVAGQSLLLENNPMNGNIMGSPFVVPQTTEVGLKGPTVPYYEKINSVPAVDQELQELL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 EELTKIQDPSPNELDLEKILGTKPEEPLVLDHPQATLSTTPKPSVQMSHLESLASSKEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELTKIQDPSPNELDLEKILGTKPEEPLVLDHPQATLSTTPKPSVQMSHLESLASSKEFA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 SSCSQVTGMSLQIPSSSTGISYSIPSTSKQIVSPSSSMAQSKSQVQAMLPVALPPLPVPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSCSQVTGMSLQIPSSSTGISYSIPSTSKQIVSPSSSMAQSKSQVQAMLPVALPPLPVPQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 WHHAHQLKALAASKQGSATKQQGPTPSWSGLPPPGLSPPYRPVPSPHPPPLPLPPPPPPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WHHAHQLKALAASKQGSATKQQGPTPSWSGLPPPGLSPPYRPVPSPHPPPLPLPPPPPPF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 SPQSLMVSCMSSNTLSGSTLRGSPNALLSSMTSSSNAALGPAMPYAPEKLPSPALTQQPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPQSLMVSCMSSNTLSGSTLRGSPNALLSSMTSSSNAALGPAMPYAPEKLPSPALTQQPQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 FGPQSSILANLMSSTIKTPQGHLMSALPASNPGPSPPYRPEKLSSPGLPQQSFTPQCSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGPQSSILANLMSSTIKTPQGHLMSALPASNPGPSPPYRPEKLSSPGLPQQSFTPQCSLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 RSLTPTSNLLSQQQQQQQQQQQANVIFKPISSNSSKTLSMIMQQGMASSSPGATEPFTFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSLTPTSNLLSQQQQQQQQQQQANVIFKPISSNSSKTLSMIMQQGMASSSPGATEPFTFG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 NTKPLSHFVSEPGPQKMPSMPTTSRQPSLLHYLQQPTPTQASSATASSTATATLQLQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTKPLSHFVSEPGPQKMPSMPTTSRQPSLLHYLQQPTPTQASSATASSTATATLQLQQQQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 QQQQQQPDHSSFLLQQMMQQPQRFQRSVASDSMPALPRQGCCHLFAWTSAASSVKPQHQH
::::::::::::::::::::::::::::::::::::::: . :. .. :..:.
XP_011 QQQQQQPDHSSFLLQQMMQQPQRFQRSVASDSMPALPRQQEEQ----RSGLMAMTPERQN
610 620 630 640 650
670 680 690 700 710 720
pF1KE1 GSSFTSRQDPQPGDVSPSNITHVDKACKLGEARHPQVSLGRQPPSCQALGSESFLPGSSF
.. :.: .: .. ..: . :. .: :. : .:: .: .... ::
XP_011 --AYISQQ-MSPFEAVQEQVT---SKCSRIKASPPS-SKHLMPPRT-GLLQNNLSPGMIP
660 670 680 690 700
730 740 750 760 770
pF1KE1 AHELARVTSSYSTSEAAPWGSWDPKAWRQVPAPLLPSCDATARGTEIRSYGNDP
XP_011 LTRHQSCEGMGVISPTLGKRQGIFTSSPQCPILSHSGQTPLGRLDSVCQHMQSPKATPPE
710 720 730 740 750 760
>>XP_016884678 (OMIM: 300120,300758) PREDICTED: mastermi (708 aa)
initn: 4564 init1: 3914 opt: 3917 Z-score: 1524.7 bits: 292.8 E(85289): 3.4e-78
Smith-Waterman score: 4644; 91.5% identity (91.5% similar) in 774 aa overlap (1-774:1-708)
10 20 30 40 50 60
pF1KE1 MDDWKSRLVIKSMLPHFAMVGNRQEPRKLQESGKKPSWMEEEDLSFLYKSSPGRKHQGTV
::::::::::::::::::::::::::::::::: ::
XP_016 MDDWKSRLVIKSMLPHFAMVGNRQEPRKLQESG-------------------------TV
10 20 30
70 80 90 100 110 120
pF1KE1 KRRQEEDHFQFPDMADGGYPNKIKRPCLEDVTLAMGPGAHPSTACAELQVPPLTINPSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRRQEEDHFQFPDMADGGYPNKIKRPCLEDVTLAMGPGAHPSTACAELQVPPLTINPSPA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 AMGVAGQSLLLENNPMNGNIMGSPFVVPQTTEVGLKGPTVPYYEKINSVPAVDQELQELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AMGVAGQSLLLENNPMNGNIMGSPFVVPQTTEVGLKGPTVPYYEKINSVPAVDQELQELL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 EELTKIQDPSPNELDLEKILGTKPEEPLVLDHPQATLSTTPKPSVQMSHLESLASSKEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EELTKIQDPSPNELDLEKILGTKPEEPLVLDHPQATLSTTPKPSVQMSHLESLASSKEFA
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE1 SSCSQVTGMSLQIPSSSTGISYSIPSTSKQIVSPSSSMAQSKSQVQAMLPVALPPLPVPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSCSQVTGMSLQIPSSSTGISYSIPSTSKQIVSPSSSMAQSKSQVQAMLPVALPPLPVPQ
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 WHHAHQLKALAASKQGSATKQQGPTPSWSGLPPPGLSPPYRPVPSPHPPPLPLPPPPPPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WHHAHQLKALAASKQGSATKQQGPTPSWSGLPPPGLSPPYRPVPSPHPPPLPLPPPPPPF
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE1 SPQSLMVSCMSSNTLSGSTLRGSPNALLSSMTSSSNAALGPAMPYAPEKLPSPALTQQPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPQSLMVSCMSSNTLSGSTLRGSPNALLSSMTSSSNAALGPAMPYAPEKLPSPALTQQPQ
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE1 FGPQSSILANLMSSTIKTPQGHLMSALPASNPGPSPPYRPEKLSSPGLPQQSFTPQCSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGPQSSILANLMSSTIKTPQGHLMSALPASNPGPSPPYRPEKLSSPGLPQQSFTPQCSLI
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE1 RSLTPTSNLLSQQQQQQQQQQQANVIFKPISSNSSKTLSMIMQQGMASSSPGATEPFTFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSLTPTSNLLSQQQQQQQQQQQANVIFKPISSNSSKTLSMIMQQGMASSSPGATEPFTFG
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE1 NTKPLSHFVSEPGPQKMPSMPTTSRQPSLLHYLQQPTPTQASSATASSTATATLQLQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTKPLSHFVSEPGPQKMPSMPTTSRQPSLLHYLQQPTPTQASSATASSTATATLQLQQQQ
520 530 540 550 560 570
610 620 630 640 650 660
pF1KE1 QQQQQQPDHSSFLLQQMMQQPQRFQRSVASDSMPALPRQGCCHLFAWTSAASSVKPQHQH
:::::::::::::::::::::::::::::::::::::::
XP_016 QQQQQQPDHSSFLLQQMMQQPQRFQRSVASDSMPALPRQ---------------------
580 590 600 610
670 680 690 700 710 720
pF1KE1 GSSFTSRQDPQPGDVSPSNITHVDKACKLGEARHPQVSLGRQPPSCQALGSESFLPGSSF
::::::::::::::::::::::::::::::::::::::::
XP_016 --------------------THVDKACKLGEARHPQVSLGRQPPSCQALGSESFLPGSSF
620 630 640 650
730 740 750 760 770
pF1KE1 AHELARVTSSYSTSEAAPWGSWDPKAWRQVPAPLLPSCDATARGTEIRSYGNDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHELARVTSSYSTSEAAPWGSWDPKAWRQVPAPLLPSCDATARGTEIRSYGNDP
660 670 680 690 700
>>NP_001170936 (OMIM: 300120,300758) mastermind-like dom (998 aa)
initn: 3914 init1: 3914 opt: 3915 Z-score: 1521.5 bits: 292.7 E(85289): 5.2e-78
Smith-Waterman score: 4080; 87.9% identity (91.4% similar) in 717 aa overlap (1-717:1-680)
10 20 30 40 50 60
pF1KE1 MDDWKSRLVIKSMLPHFAMVGNRQEPRKLQESGKKPSWMEEEDLSFLYKSSPGRKHQGTV
::::::::::::::::::::::::::::::::: ::
NP_001 MDDWKSRLVIKSMLPHFAMVGNRQEPRKLQESG-------------------------TV
10 20 30
70 80 90 100 110 120
pF1KE1 KRRQEEDHFQFPDMADGGYPNKIKRPCLEDVTLAMGPGAHPSTACAELQVPPLTINPSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRRQEEDHFQFPDMADGGYPNKIKRPCLEDVTLAMGPGAHPSTACAELQVPPLTINPSPA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 AMGVAGQSLLLENNPMNGNIMGSPFVVPQTTEVGLKGPTVPYYEKINSVPAVDQELQELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AMGVAGQSLLLENNPMNGNIMGSPFVVPQTTEVGLKGPTVPYYEKINSVPAVDQELQELL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 EELTKIQDPSPNELDLEKILGTKPEEPLVLDHPQATLSTTPKPSVQMSHLESLASSKEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EELTKIQDPSPNELDLEKILGTKPEEPLVLDHPQATLSTTPKPSVQMSHLESLASSKEFA
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE1 SSCSQVTGMSLQIPSSSTGISYSIPSTSKQIVSPSSSMAQSKSQVQAMLPVALPPLPVPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSCSQVTGMSLQIPSSSTGISYSIPSTSKQIVSPSSSMAQSKSQVQAMLPVALPPLPVPQ
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 WHHAHQLKALAASKQGSATKQQGPTPSWSGLPPPGLSPPYRPVPSPHPPPLPLPPPPPPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WHHAHQLKALAASKQGSATKQQGPTPSWSGLPPPGLSPPYRPVPSPHPPPLPLPPPPPPF
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE1 SPQSLMVSCMSSNTLSGSTLRGSPNALLSSMTSSSNAALGPAMPYAPEKLPSPALTQQPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPQSLMVSCMSSNTLSGSTLRGSPNALLSSMTSSSNAALGPAMPYAPEKLPSPALTQQPQ
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE1 FGPQSSILANLMSSTIKTPQGHLMSALPASNPGPSPPYRPEKLSSPGLPQQSFTPQCSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGPQSSILANLMSSTIKTPQGHLMSALPASNPGPSPPYRPEKLSSPGLPQQSFTPQCSLI
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE1 RSLTPTSNLLSQQQQQQQQQQQANVIFKPISSNSSKTLSMIMQQGMASSSPGATEPFTFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSLTPTSNLLSQQQQQQQQQQQANVIFKPISSNSSKTLSMIMQQGMASSSPGATEPFTFG
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE1 NTKPLSHFVSEPGPQKMPSMPTTSRQPSLLHYLQQPTPTQASSATASSTATATLQLQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTKPLSHFVSEPGPQKMPSMPTTSRQPSLLHYLQQPTPTQASSATASSTATATLQLQQQQ
520 530 540 550 560 570
610 620 630 640 650 660
pF1KE1 QQQQQQPDHSSFLLQQMMQQPQRFQRSVASDSMPALPRQGCCHLFAWTSAASSVKPQHQH
::::::::::::::::::::::::::::::::::::::: . :. .. :..:.
NP_001 QQQQQQPDHSSFLLQQMMQQPQRFQRSVASDSMPALPRQQEEQ----RSGLMAMTPERQN
580 590 600 610 620 630
670 680 690 700 710 720
pF1KE1 GSSFTSRQDPQPGDVSPSNITHVDKACKLGEARHPQVSLGRQPPSCQALGSESFLPGSSF
.. :.: .: .. ..: . :. .: :. : .:: .: .... ::
NP_001 --AYISQQ-MSPFEAVQEQVT---SKCSRIKASPPS-SKHLMPPRT-GLLQNNLSPGMIP
640 650 660 670 680
730 740 750 760 770
pF1KE1 AHELARVTSSYSTSEAAPWGSWDPKAWRQVPAPLLPSCDATARGTEIRSYGNDP
NP_001 LTRHQSCEGMGVISPTLGKRQGIFTSSPQCPILSHSGQTPLGRLDSVCQHMQSPKATPPE
690 700 710 720 730 740
774 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 07:26:38 2016 done: Sat Nov 5 07:26:40 2016
Total Scan time: 12.490 Total Display time: 0.220
Function used was FASTA [36.3.4 Apr, 2011]