Result of FASTA (ccds) for
pF1KE1024
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1024, 808 aa
1>>>pF1KE1024 808 - 808 aa - 808 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.5107+/-0.00111; mu= -18.9141+/- 0.067
mean_var=552.8120+/-113.381, 0's: 0 Z-trim(117.3): 67 B-trim: 0 in 0/52
Lambda= 0.054549
statistics sampled from 18003 (18068) to 18003 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.805), E-opt: 0.2 (0.555), width: 16
Scan time: 5.480
The best scores are: opt bits E(32554)
CCDS10676.2 TBC1D10B gene_id:26000|Hs108|chr16 ( 808) 5468 445.2 2.1e-124
CCDS13874.1 TBC1D10A gene_id:83874|Hs108|chr22 ( 508) 1952 168.3 2.9e-41
CCDS56227.1 TBC1D10A gene_id:83874|Hs108|chr22 ( 515) 1928 166.4 1.1e-40
CCDS8162.1 TBC1D10C gene_id:374403|Hs108|chr11 ( 446) 1368 122.3 1.8e-27
>>CCDS10676.2 TBC1D10B gene_id:26000|Hs108|chr16 (808 aa)
initn: 5468 init1: 5468 opt: 5468 Z-score: 2346.9 bits: 445.2 E(32554): 2.1e-124
Smith-Waterman score: 5468; 99.9% identity (100.0% similar) in 808 aa overlap (1-808:1-808)
10 20 30 40 50 60
pF1KE1 METGTAPLVAPPRRHGAPAAPSPPPRGSRAGPVVVVAPGPPVTTATSAPVTLVAPGEARP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 METGTAPLVAPPRRHGAPAAPSPPPRGSRAGPVVVVAPGPPVTTATSAPVTLVAPGEARP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 AWVPGSAETSAPAPAPAPAPAPAVTGSTVVVLTLEASPEAPKPQLPSGPESPEPAAVAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 AWVPGSAETSAPAPAPAPAPAPAVTGSTVVVLTLEASPEAPKPQLPSGPESPEPAAVAGV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ETSRALAAGADSPKTEEARPSPAPGPGTPTGTPTRTPSRTAPGALTAKPPLAPKPGTTVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 ETSRALAAGADSPKTEEARPSPAPGPGTPTGTPTRTPSRTAPGALTAKPPLAPKPGTTVA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 SGVTARSASGQVTGGHGAAAATSASAGQAPDDPSGPGTGPSGTCEAPVAVVTVTPAPEPA
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
CCDS10 SGVTARSASGQVTGGHGAAAATSASAGQAPEDPSGPGTGPSGTCEAPVAVVTVTPAPEPA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 ENSQDLGSTSSLGPGISGPRGQAPDTLSYLDSVSLMSGTLESLADDVSSMGSDSEINGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 ENSQDLGSTSSLGPGISGPRGQAPDTLSYLDSVSLMSGTLESLADDVSSMGSDSEINGLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 LRKTDKYGFLGGSQYSGSLESSIPVDVARQRELKWLDMFSNWDKWLSRRFQKVKLRCRKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LRKTDKYGFLGGSQYSGSLESSIPVDVARQRELKWLDMFSNWDKWLSRRFQKVKLRCRKG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 IPSSLRAKAWQYLSNSKELLEQNPGKFEELERAPGDPKWLDVIEKDLHRQFPFHEMFAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 IPSSLRAKAWQYLSNSKELLEQNPGKFEELERAPGDPKWLDVIEKDLHRQFPFHEMFAAR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 GGHGQQDLYRILKAYTIYRPDEGYCQAQAPVAAVLLMHMPAEQAFWCLVQICDKYLPGYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 GGHGQQDLYRILKAYTIYRPDEGYCQAQAPVAAVLLMHMPAEQAFWCLVQICDKYLPGYY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 SAGLEAIQLDGEIFFALLRRASPLAHRHLRRQRIDPVLYMTEWFMCIFARTLPWASVLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 SAGLEAIQLDGEIFFALLRRASPLAHRHLRRQRIDPVLYMTEWFMCIFARTLPWASVLRV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 WDMFFCEGVKIIFRVALVLLRHTLGSVEKLRSCQGMYETMEQLRNLPQQCMQEDFLVHEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 WDMFFCEGVKIIFRVALVLLRHTLGSVEKLRSCQGMYETMEQLRNLPQQCMQEDFLVHEV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 TNLPVTEALIERENAAQLKKWRETRGELQYRPSRRLHGSRAIHEERRRQQPPLGPSSSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 TNLPVTEALIERENAAQLKKWRETRGELQYRPSRRLHGSRAIHEERRRQQPPLGPSSSLL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 SLPGLKSRGSRAAGGAPSPPPPVRRASAGPAPGPVVTAEGLHPSLPSPTGNSTPLGSSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 SLPGLKSRGSRAAGGAPSPPPPVRRASAGPAPGPVVTAEGLHPSLPSPTGNSTPLGSSKE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 TRKQEKERQKQEKERQKQEKEREKERQKQEKEREKQEKEREKQEKERQKQEKKAQGRKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 TRKQEKERQKQEKERQKQEKEREKERQKQEKEREKQEKEREKQEKERQKQEKKAQGRKLS
730 740 750 760 770 780
790 800
pF1KE1 LRRKADGPPGPHDGGDRPSAEARQDAYF
::::::::::::::::::::::::::::
CCDS10 LRRKADGPPGPHDGGDRPSAEARQDAYF
790 800
>>CCDS13874.1 TBC1D10A gene_id:83874|Hs108|chr22 (508 aa)
initn: 1965 init1: 1922 opt: 1952 Z-score: 854.4 bits: 168.3 E(32554): 2.9e-41
Smith-Waterman score: 1969; 59.0% identity (79.0% similar) in 505 aa overlap (255-741:6-504)
230 240 250 260 270 280
pF1KE1 EAPVAVVTVTPAPEPAENSQDLGSTSSLGPGISGPRGQAP-DTLSYLDSVSLMSGTLESL
: .:::. : ..:: :: .: .
CCDS13 MAKSNGENGPRAPAAGESLSGTRE-SLAQGPDAAT
10 20 30
290 300 310 320 330 340
pF1KE1 ADDVSSMGSDSEINGLALRKTDKYGFLGGSQYS-GSLESSIPVDVARQRELKWLDMFSNW
.:..::.::::: ::.: :. ::.::. ::: . :.:: .:..: :::: :::::..::
CCDS13 TDELSSLGSDSEANGFAERRIDKFGFIVGSQGAEGALEE-VPLEVLRQRESKWLDMLNNW
40 50 60 70 80 90
350 360 370 380 390 400
pF1KE1 DKWLSRRFQKVKLRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEELERAPGDPKWLDV
:::.... .:..:::.:::: :::..::::::..: :.::::::.::. .:::::::::
CCDS13 DKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDELDMSPGDPKWLDV
100 110 120 130 140 150
410 420 430 440 450 460
pF1KE1 IEKDLHRQFPFHEMFAARGGHGQQDLYRILKAYTIYRPDEGYCQAQAPVAAVLLMHMPAE
::.::::::::::::..:::::::::.:.:::::.:::.:::::::::.:::::::::::
CCDS13 IERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIAAVLLMHMPAE
160 170 180 190 200 210
470 480 490 500 510 520
pF1KE1 QAFWCLVQICDKYLPGYYSAGLEAIQLDGEIFFALLRRASPLAHRHLRRQRIDPVLYMTE
::::::::::.:::::::: ::::::::::.:.::...::.::.:: ::.:::.:::::
CCDS13 QAFWCLVQICEKYLPGYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLSRQKIDPLLYMTE
220 230 240 250 260 270
530 540 550 560 570 580
pF1KE1 WFMCIFARTLPWASVLRVWDMFFCEGVKIIFRVALVLLRHTLGSVEKLRSCQGMYETMEQ
:::: :.:::::.::::::::::::::::::::.::::.:.::: ::...:::.:::.:.
CCDS13 WFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLKHALGSPEKVKACQGQYETIER
280 290 300 310 320 330
590 600 610 620 630 640
pF1KE1 LRNLPQQCMQEDFLVHEVTNLPVTEALIERENAAQLKKWRETRGELQYRPSRRLHGSRAI
::.: . ::: :::.::..::::: ::::. ::..:.::::::: : ::::..::
CCDS13 LRSLSPKIMQEAFLVQEVVELPVTERQIEREHLIQLRRWQETRGELQCRSPPRLHGAKAI
340 350 360 370 380 390
650 660 670 680 690
pF1KE1 HEERRRQQPPLGPSSSLLSLP-GLKSRGSRAAGGAPSPPPPV----RRASAG-------P
. . .: : :: :. :: ::.: :.:: . :. : :
CCDS13 LDAEPGPRPALQPSPSI-RLPLDAPLPGSKAK---PKPPKQAQKEQRKQMKGRGQLEKPP
400 410 420 430 440
700 710 720 730 740
pF1KE1 APGP--VVTAEG-LHPSLPSPTGNSTPLGSS-KETRKQEKERQKQEKERQKQEKEREKER
::. ::.: : : : .:.: :. .. : . ...... .::.:
CCDS13 APNQAMVVAAAGDACPPQHVPPKDSAPKDSAPQDLAPQVSAHHRSQESLTSQESEDTYL
450 460 470 480 490 500
750 760 770 780 790 800
pF1KE1 QKQEKEREKQEKEREKQEKERQKQEKKAQGRKLSLRRKADGPPGPHDGGDRPSAEARQDA
>>CCDS56227.1 TBC1D10A gene_id:83874|Hs108|chr22 (515 aa)
initn: 1963 init1: 1775 opt: 1928 Z-score: 844.1 bits: 166.4 E(32554): 1.1e-40
Smith-Waterman score: 1945; 58.2% identity (77.9% similar) in 512 aa overlap (255-741:6-511)
230 240 250 260 270 280
pF1KE1 EAPVAVVTVTPAPEPAENSQDLGSTSSLGPGISGPRGQAP-DTLSYLDSVSLMSGTLESL
: .:::. : ..:: :: .: .
CCDS56 MAKSNGENGPRAPAAGESLSGTRE-SLAQGPDAAT
10 20 30
290 300 310 320 330
pF1KE1 ADDVSSMGSDSEINGLALRKTDKYGFLGGSQYS-GS-------LESSIPVDVARQRELKW
.:..::.::::: ::.: :. ::.::. ::: . :. :: .:..: :::: ::
CCDS56 TDELSSLGSDSEANGFAERRIDKFGFIVGSQGAEGAPCPLLHRLEE-VPLEVLRQRESKW
40 50 60 70 80 90
340 350 360 370 380 390
pF1KE1 LDMFSNWDKWLSRRFQKVKLRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEELERAPG
:::..:::::.... .:..:::.:::: :::..::::::..: :.::::::.::. .::
CCDS56 LDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDELDMSPG
100 110 120 130 140 150
400 410 420 430 440 450
pF1KE1 DPKWLDVIEKDLHRQFPFHEMFAARGGHGQQDLYRILKAYTIYRPDEGYCQAQAPVAAVL
:::::::::.::::::::::::..:::::::::.:.:::::.:::.:::::::::.::::
CCDS56 DPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIAAVL
160 170 180 190 200 210
460 470 480 490 500 510
pF1KE1 LMHMPAEQAFWCLVQICDKYLPGYYSAGLEAIQLDGEIFFALLRRASPLAHRHLRRQRID
:::::::::::::::::.:::::::: ::::::::::.:.::...::.::.:: ::.::
CCDS56 LMHMPAEQAFWCLVQICEKYLPGYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLSRQKID
220 230 240 250 260 270
520 530 540 550 560 570
pF1KE1 PVLYMTEWFMCIFARTLPWASVLRVWDMFFCEGVKIIFRVALVLLRHTLGSVEKLRSCQG
:.::::::::: :.:::::.::::::::::::::::::::.::::.:.::: ::...:::
CCDS56 PLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLKHALGSPEKVKACQG
280 290 300 310 320 330
580 590 600 610 620 630
pF1KE1 MYETMEQLRNLPQQCMQEDFLVHEVTNLPVTEALIERENAAQLKKWRETRGELQYRPSRR
.:::.:.::.: . ::: :::.::..::::: ::::. ::..:.::::::: : :
CCDS56 QYETIERLRSLSPKIMQEAFLVQEVVELPVTERQIEREHLIQLRRWQETRGELQCRSPPR
340 350 360 370 380 390
640 650 660 670 680
pF1KE1 LHGSRAIHEERRRQQPPLGPSSSLLSLP-GLKSRGSRAAGGAPSPPPPV----RRASAG-
:::..:: . . .: : :: :. :: ::.: :.:: . :. :
CCDS56 LHGAKAILDAEPGPRPALQPSPSI-RLPLDAPLPGSKAK---PKPPKQAQKEQRKQMKGR
400 410 420 430 440
690 700 710 720 730
pF1KE1 ------PAPGP--VVTAEG-LHPSLPSPTGNSTPLGSS-KETRKQEKERQKQEKERQKQE
:::. ::.: : : : .:.: :. .. : . ...... .::
CCDS56 GQLEKPPAPNQAMVVAAAGDACPPQHVPPKDSAPKDSAPQDLAPQVSAHHRSQESLTSQE
450 460 470 480 490 500
740 750 760 770 780 790
pF1KE1 KEREKERQKQEKEREKQEKEREKQEKERQKQEKKAQGRKLSLRRKADGPPGPHDGGDRPS
.:
CCDS56 SEDTYL
510
>>CCDS8162.1 TBC1D10C gene_id:374403|Hs108|chr11 (446 aa)
initn: 1308 init1: 1308 opt: 1368 Z-score: 606.8 bits: 122.3 E(32554): 1.8e-27
Smith-Waterman score: 1368; 47.1% identity (73.6% similar) in 420 aa overlap (283-694:15-431)
260 270 280 290 300 310
pF1KE1 GPGISGPRGQAPDTLSYLDSVSLMSGTLESLADDVSSMGSDSEINGLA-LRKTDKYGFLG
: :: ::.:::::..: . :..:.:::.:
CCDS81 MAQALGEDLVQPPELQDDSSSLGSDSELSGPGPYRQADRYGFIG
10 20 30 40
320 330 340 350 360 370
pF1KE1 GSQYSGSLESSIPVDVARQRELKWLDMFSNWDKWLSRRFQKVKLRCRKGIPSSLRAKAWQ
::. . . :.:. ::::.::..: :.:.: .:::..:::..:::::::.:::. :
CCDS81 GSSAEPG-PGHPPADLIRQREMKWVEMTSHWEKTMSRRYKKVKMQCRKGIPSALRARCWP
50 60 70 80 90 100
380 390 400 410 420 430
pF1KE1 YLSNSKELLEQNPGKFEELERAPGDPKWLDVIEKDLHRQFPFHEMFAARGGHGQQDLYRI
: ... ...:: ..:: .:::::.:...: .:::::::.::::.. ::::: : ..
CCDS81 LLCGAHVCQKNSPGTYQELAEAPGDPQWMETIGRDLHRQFPLHEMFVSPQGHGQQGLLQV
110 120 130 140 150 160
440 450 460 470 480 490
pF1KE1 LKAYTIYRPDEGYCQAQAPVAAVLLMHMPAEQAFWCLVQICDKYLPGYYSAGLEAIQLDG
:::::.:::..::::::.:::::::::.: :.:::::::::. ::::::. .::..::.
CCDS81 LKAYTLYRPEQGYCQAQGPVAAVLLMHLPPEEAFWCLVQICEVYLPGYYGPHMEAVRLDA
170 180 190 200 210 220
500 510 520 530 540 550
pF1KE1 EIFFALLRRASPLAHRHLRRQRIDPVLYMTEWFMCIFARTLPWASVLRVWDMFFCEGVKI
:.:.::::: : .:.::.. . :.::. :::.:.:::.::. .:::::: :. ::...
CCDS81 EVFMALLRRLLPHVHKHLQQVGVGPLLYLPEWFLCLFARSLPFPTVLRVWDAFLSEGARV
230 240 250 260 270 280
560 570 580 590 600 610
pF1KE1 IFRVALVLLRHTLGSVEKLRSCQGMYETMEQLRNLPQQCMQEDFLVHEVTNLPVTEALIE
.:::.:.:.: .::..:. .: :. ::. :: .: .::. .. .: .. ..: ..
CCDS81 LFRVGLTLVRLALGTAEQRGACPGLLETLGALRAIPPAQLQEEAFMSQVHSVVLSERDLQ
290 300 310 320 330 340
620 630 640 650 660
pF1KE1 RENAAQLKKWRETRGELQYRPSRRLHGSRAIHEER-----RRQQPPLGPSSSLLSLPGLK
:: ::: . .. ::. :: :..:: : . :: : : .. : .
CCDS81 REIKAQLAQLPDSAPGPPPRPQVRLAGAQAIFEAQQLAGVRRGAKPEVPR--IVVQPPEE
350 360 370 380 390 400
670 680 690 700 710 720
pF1KE1 SRGSRAAGGAPSPPPP--VRRASAGPAPGPVVTAEGLHPSLPSPTGNSTPLGSSKETRKQ
: : . . . :: . : ::
CCDS81 PRPPRRKPQTRGKTFHGLLTRARGPPIEGPPRPQRGSTSFLDTRF
410 420 430 440
808 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 07:27:18 2016 done: Sat Nov 5 07:27:19 2016
Total Scan time: 5.480 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]